Last updated: 2025-03-13 429297 annotations 4738 curated publications
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Ontology term: decreased protein localization to nucleus (FYPO:0004455)
Definition Parents
A cell phenotype in which the localization of a protein to the nucleus is decreased.
External links: BioPortal
Single locus phenotype annotations for FYPO:0004455 and its descendants
Cell
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+ decreased protein localization to nucleus
ssp2Δ affecting sre1
tor2-L2048S(aa) affecting crf1
+ decreased protein import into nucleus
imp1Δ affecting mid1
klp6Δ affecting klp5
+ decreased protein localization to nuclear envelope during vegetative growth
bqt4-C394-432(1-393 Δaa) affecting bqt4
bqt4-C414-432(1-413 Δaa) affecting bqt4
+ decreased protein localization to nuclear periphery
pmt3-KallR(K14R,K30R,K39R,K51R,K53R,K54R,K60R,K63R,K71R aa)
alm1Δ affecting cut11 , cut8 , mts4 , nup211 , rpt2
bqt4Δ affecting lem2
dcr1-N1344A(aa) affecting dcr1
dcr1-R1322A,Δ-C33(R1322A,1342-1374 aa) affecting dcr1
dcr1-S1349A(aa) affecting dcr1
dcr1-SHSS(C1275S,C1350S,C1352S aa) affecting dcr1
dcr1-Y1348A(aa) affecting dcr1
dsh1Δ affecting taz1
lem2Δ affecting taz1
+ decreased protein localization to nuclear periphery during mitotic interphase
alm1Δ affecting mad2
+ decreased protein localization to nucleoplasm during cellular response to DNA damage
nse1-ΔRING(184-219 Δaa) affecting nse4
rtt109Δ affecting pku70
set9Δ affecting crb2
+ decreased protein localization to nucleoplasm during cellular response to hydrogen peroxide
clp1-3A(T363A,T382A,T453A aa) affecting clp1
clp1-6A-b(S396A,S408A,S467A,S468A,S493A,S513A aa) affecting clp1
rad3Δ affecting clp1
+ decreased protein localization to nucleoplasm during cellular response to hydroxyurea
clp1-3A(T363A,T382A,T453A aa) affecting clp1
+ decreased protein localization to nucleus during cellular response to calcium ion
cmk1+[Overexpression] affecting prz1
+ decreased protein localization to nucleus during cellular response to hydrogen peroxide
cut15-85(G419S,G450S aa) affecting pap1
ptc4-R8A,R10A,R27A(aa) affecting sty1
+ decreased protein localization to nucleus during cellular response to hydroxyurea
cds1-FHA(S78A,H81A aa) affecting tos4
cds1Δ affecting tos4
pcf1Δ affecting cds1
rgf1-ΔNterm(1-303 Δaa) affecting rgf1
rgf1-NLS*(R408A,R409A,R410A,R411A aa) affecting rgf1
+ decreased protein localization to nucleus during cellular response to osmotic stress
crm1-467(H467Y aa) affecting sty1
+ decreased protein localization to nucleus during cellular response to salt stress
pcr1Δ affecting sty1
sin1Δ affecting sty1
+ decreased protein localization to nucleus during mitosis
cdc2-as(F84G aa) affecting alp7
+ decreased protein localization to nucleus during mitotic interphase
ago1-NT(427-834 Δaa)[Overexpression] affecting cdc25
klp9-Δ38C(596-633 Δaa) affecting klp9
+ decreased protein localization to nucleus during nitrogen starvation
gtr1Δ affecting gaf1
gtr2Δ affecting gaf1
lam2Δ affecting gaf1
npr2Δ affecting gaf1
npr3Δ affecting gaf1
ppe1Δ affecting gaf1
ssp2Δ affecting ste11
+ decreased protein localization to nucleus during prophase I
cdc2-as(F84G aa) affecting alp7
mug20Δ/mug20Δ affecting rec25
rec10Δ/rec10Δ affecting mug20
+ decreased protein localization to nucleus during stationary phase
cdc2-K33R(aa) affecting cdc2
cdc2-Y15E(aa) affecting cdc2
+ decreased protein localization to nucleus during vegetative growth
ssl3-29(unknown)
acr1-936(unknown) affecting nuc1
alp7Δ affecting alp14
cdc17-1-175/M20A(176-768,M20A aa) affecting cdc17
cdt2+[Overexpression] affecting spd1
cut11-1(L521F aa) affecting cut11
cut11-2(C525R aa) affecting cut11
cut11-6(T498I aa) affecting cut11
cyr1Δ affecting cgs1 , pka1
epe1Δ affecting ssp2
imp1Δ affecting cdc48 , rpn8
lem2+[Overexpression] affecting nsp1
lem2Δ affecting nsp1
man1+[Overexpression] affecting nsp1
mid1-NLS*(R691Q,K692N,K693S,R694Q,K695S aa)[Overexpression] affecting mid1
pat1+[Overexpression] affecting ste11
pcf1Δ affecting pcf2 , pcf3
pfh1-m21(M21A aa)[Knockdown] affecting pfh1
pim1-d1(unknown) affecting nsp1
pim1-F201S(aa) affecting alp7
rad1Δ affecting hus1
slm9Δ affecting hip1
ssl3-29(unknown) affecting mis4
+ decreased protein localization to nucleus, with protein mislocalized to cytoplasm
cbf12-395-465(1-394,466-963 Δaa)[Overexpression] affecting cbf12
ccq1-KR54AA(aa) affecting ccq1
cdc17-1-175/ΔNLS(176-768,K62A,R63A,K64A aa) affecting cdc17
cdc17-66-175(1-65,176-768 Δaa) affecting cdc17
cpc2Δ affecting pat1
cut15-122(C395R aa)[Knockdown] affecting cut15
cut8-563(S201P aa) affecting mts4
cyr1Δ affecting pka1
dsk1Δ affecting srp2
fep1-5-261(aa) affecting fep1
hsk1-1312(S314I aa) affecting hsk1
int6Δ affecting rpn501 , rpn502
moe1Δ affecting rpn501 , rpn502
pcr1Δ affecting atf1
rad21-K1(unknown) affecting pds5
saf5+[Overexpression] affecting smb1
sla1-R256E,R257L(aa) affecting sla1
sla1ΔC229-298(aa) affecting sla1
swi3Δ affecting swi1
top2-1-40/SV-Δ-Sph(2-41,M1MPKKKRKV,1200-1485) affecting top2
top2-1-40/SV-Δ-Xba(2-41,M1MPKKKRKV,1221-1485) affecting top2
top2-1-74/SV-Δ-Sph(2-75,M1MPKKKRKV,1200-1485) affecting top2
top2-1-74/SV-Δ-Xba(2-75,M1MPKKKRKV,1221-1485) affecting top2
top2-26-40/SV-Δ-Sph(27-41,T26TPKKKRKV,1200-1485) affecting top2
top2Δ(1-17)-Δ-Sph(1-18,1200-1485 Δaa) affecting top2
top2Δ(1-17)-Δ-Xba(1-18,1221-1485 Δaa) affecting top2
top2Δ(42-74)-Δ-Sph(43-75,1200-1485 Δaa) affecting top2
top2Δ(42-74)-Δ-Xba(43-75,1221-1485 Δaa) affecting top2
top2Δ-Sph(1200-1485 Δaa) affecting top2
yip11+[Overexpression] affecting smb1
+ decreased protein localization to nucleus, with protein mislocalized to cytoplasm during mitosis
alp7-5A-a(S50A,S51A,T100A,T116A,T131A aa) affecting alp7
alp7-RARA(R122A,R124A aa) affecting alp14 , alp7
alp7Δ61-116(aa) affecting alp7
+ decreased protein localization to nucleus, with protein mislocalized to cytoplasmic foci
hsp104Δ affecting dcr1
Multi-locus phenotype annotations for FYPO:0004455 and its descendants
Cell
Show details ...
Filters:
+ decreased protein localization to nucleus
gsk31Δ gsk3Δ affecting sre1
gsk31Δ gsk3Δ ssp2Δ affecting sre1
gsk31Δ ssp2Δ affecting sre1
gsk3Δ ssp2Δ affecting sre1
+ decreased protein import into nucleus
cdc13+[Knockdown] cig1Δ affecting cdc2
cdc13+[Knockdown] cig2Δ affecting cdc2
nro1Δ sre1-N(441-900 Δaa) affecting ofd1
+ decreased protein localization to nuclear periphery
dsh1Δ lem2Δ affecting taz1
+ decreased protein localization to nucleoplasm during cellular response to hydrogen peroxide
cds1Δ chk1Δ affecting clp1
pmk1Δ rad3Δ affecting clp1
+ decreased protein localization to nucleus during cellular response to hydroxyurea
cdc21-M68(unknown) cds1Δ affecting tos4
cdc22-M45(unknown) cds1Δ affecting tos4
+ decreased protein localization to nucleus during mitosis
cdc25-3A(S99A,S192A,S359A aa) rad24+[Overexpression] affecting cdc25
+ decreased protein localization to nucleus during vegetative growth
cdc24+[Overexpression] dna2-L1097S(aa)[Overexpression] affecting cdc24 , dna2
+ decreased protein localization to nucleus, with protein mislocalized to cytoplasm
rad24Δ sal3Δ
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