Last updated: 2025-03-13 429297 annotations 4738 curated publications
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Ontology term: increased protein-protein interaction (FYPO:0001571)
Definition Parents
A molecular function phenotype in which the binding of one protein to another occurs to a greater extent than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes.
External links: BioPortal
Single locus phenotype annotations for FYPO:0001571 and its descendants
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+ increased protein-protein interaction
ain1-R216E(aa) affecting ain1 and act1
apc14Δ affecting mad2 and cut20
byr2-ΔC-terminus(392-659 Δaa) affecting byr2 and byr2 , byr2 and ras1
byr2-S87A,T94A,S136A,S402A,S566A,S650A(aa)[Ectopic] affecting byr2 and rad24
byr2-S87A,T94A,S136A,S402A,S566A,S654A(aa)[Ectopic] affecting byr2 and rad24
ccq1(1-441)(442-735 Δaa) affecting ccq1 and clr3
ccq1(501-735)(1-500 Δaa) affecting ccq1 and clr3
cdc1-CΔ453-462(aa) affecting cdc1 and cdc27
cdc1-J8(K83KGVPLK) affecting cdc1 and cdc27
cdc1-NΔ2-25(aa) affecting cdc1 and cdc27
cdc27(1-169)(170-372 Δaa)[Overexpression] affecting cdc27 and cdc1
cdc27-D1(160-372 Δaa)[Overexpression] affecting cdc27 and cdc1
cdc42-G12V(aa) affecting cdc42 and shk2 , shk1 and cdc42
cdc48-A360D(aa) affecting cdc48 and ufd1
cdc48-A580V(aa) affecting cdc48 and ufd1
cdc48-E319K(aa) affecting cdc48 and ufd1
cdc48-N552I(aa) affecting cdc48 and ufd1
cdc48-R758C(aa) affecting cdc48 and ufd1
cnp20-14A(S3A,T8A,S12A,S13A,S14A,T21A,S23A,T29A,S31A,S33A,T36A,S39A,T43A,T45A aa) affecting ccp1
cnp20-14D(S3D,T8D,S12D,S13D,S14D,T21D,S23D,T29D,S31D,S33D,T36D,S39D,T43D,T45D aa) affecting ndc80
csn5Δ affecting cul1 and ned8
cut12-1(R536*) affecting dis2 and cut12
cut12-F87L(aa) affecting plo1 and cut12
cut12-G71V,F87L(aa) affecting plo1 and cut12
cut12-G71V,T75A,T78A(aa) affecting plo1 and cut12
cut12-G71V,T75D,T78D(aa) affecting plo1 and cut12
cut12-PDSA(G71V,I72A,L73A,K83A,V85A,F87A aa) affecting plo1 and cut12
cut12-PDswap(GILKTPGTLQIKKTVNF71ILGHKLEYNYNSHMVYI aa) affecting plo1 and cut12
cut12-T75D,T78D(aa) affecting plo1 and cut12
cut12-T78D(aa) affecting plo1 and cut12
cut12-V85A,F87A(aa) affecting plo1 and cut12
cut12.s11(G71V aa) affecting plo1 and cut12
dis2Δ affecting bub1 and mad1 , bub1 and mad2
dma1Δ affecting tea4 and tip1
dni1-TMD4sL(G192L,S196L aa) affecting dni1 and dni1
dni1Δ affecting dni2 and dni2
dni2Δ affecting dni1 and dni1
dsn1-DD(S68D,S77D aa) affecting cnp3 and mis12
gpa2-R176H(aa) affecting cyr1 and gpa2
hht1-Y41F(Y42F aa) affecting hht1 and swi6
hht2-Y41F(Y42F aa) affecting swi6 and hht2
hht3-K9M(K10M aa) affecting hht3 and clr4
hht3-Y41F(Y42F aa) affecting swi6 and hht3
mad3(1-281)(282-310 Δaa) affecting mad3 and mad2 , mad3 and slp1
mad3-KEN2-AAA(K271A,E272A,N273A aa) affecting mad3 and mad2 , mad3 and slp1
mad3Δ affecting mad2 and slp1
mei2-F644A(aa) affecting mei2 and rad24
mes1-K0(K7R,K16R,K46R,K54R,K86R,K57R,K58R,K90R,K55R aa) affecting mes1 and nuc2 , mes1 and slp1
mes1-K1(K16R,K46R,K54R,K55R,K57R,K58R,K86R,K90R aa) affecting mes1 and nuc2 , mes1 and slp1
mid1-9A(S110A,S127A,S218A,S227A,S329A,S432A,S452A,S464A,S531A aa) affecting cdr2 and mid1
pcf1-ED*(Y340A,W348A aa) affecting pcn1 and pcf1
pek1-A(T238A aa) affecting pek1 and pmk1
pmt3-tpz1(243-420) affecting tpz1 and stn1
pyp1-C470S(aa) affecting sty1 and pyp1
rap1-5A(S213A,T378A,S422A,S456A,S513A aa) affecting rap1 and bqt4
rga2Δ affecting pck2 and rho2
rhb1-K120R(aa) affecting rhb1 and tor2
rhb1-N153T(aa) affecting rhb1 and tor2
rhb1-V17G(aa) affecting rhb1 and tor2
rho1-G15V,C199R(aa) affecting rho1 and pck1 , rho1 and pck2
rho2-G17V,C197S(aa) affecting rho2 and pck1 , rho2 and pck2
rho4-G23V(aa) affecting sec8 and rho4
rpn15-Δhelix(D54*) affecting dss1 and acl1 , dss1 and acl2 , dss1 and SPCC1739.08c
rum1+[Overexpression] affecting cdc13 and rum1 , rum1 and cdc2
ryh1-G23A(aa) affecting ryh1 and ric1
ryh1-Q70L(aa) affecting sin1 and gad8
sdj1-L169P(aa) affecting sdj1 and ssa1 , sdj1 and ssa2
sfr1-5A(S26A,S33A,S109A,S155A,S165A aa) affecting dmc1 and sfr1
sid2-250(E314K aa) affecting mid1 and cdr2
spc7-12TA(T77A,S221A,T257A,T338A,T366A,T395A,T413A,T422A,T453A,T507A,T529A,T552A aa) affecting bub1 and mad1
spc7-9TE(T257E,T338E,T366E,T395E,T422E,T453E,T507E,T529E,T552E aa) affecting spc7 and bub1
swi1-(750-971)(1-749 Δaa) affecting swi1 and swi3
tdk1-1L(G119GSGGGSSG) affecting bdf1 and tdk1
tdk1-2L(K184KSGGGSSG) affecting bdf1 and tdk1
tdk1-3L(F275FSGGGSSG) affecting bdf1 and tdk1
tdk1-L229P(aa) affecting bdf1 and tdk1
tea4-SH3(W167A,W168A aa) affecting tea4 and tea1
tpz1-K75A(aa) affecting tpz1 and trt1 , trt1 and ccq1
trr1Δ affecting pap1 and prr1
tsc2Δ affecting rhb1 and tor2
+ increased actin filament binding
ain1-R216E(aa) affecting act1 and ain1
+ increased anaphase-promoting complex binding
ubc11-P93L(aa) affecting mad2 , slp1
+ increased histone binding
htb1-K119R(K120R aa) affecting pob3 , spt16
+ increased histone H3-K9Me binding
swi6-V82E(aa)
+ increased microtubule binding
mal3-Q89R(aa) affecting mal3
+ increased protein-protein interaction during cellular response to oxidative stress
pin1Δ affecting rpb1 and sty1
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