id: gomodel:67c10cc400001835
title: FAD biosynthetic process (GO:0006747) and protein maturation (GO:0051604),
  (specifically FMNylation of mitochondrial proteins)
taxon: NCBITaxon:4896
status: development
date_modified: '2025-08-27'
comments:
- Also need to check cir2, ndi1, nde1, trr1, erv1, aif1, obr1?, opst2, phr1? cyc2,
  fas1(mitochondrial?)
activities:
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      date: '2025-03-07'
      provided_by:
      - http://www.pombase.org
    term: GO:0005739
  has_input:
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-07'
      provided_by:
      - http://www.pombase.org
    term: CHEBI:16238
- id: gomodel:67c10cc400001835/67c10cc400002001
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000530299
      - UniProtKB:P9WHH3
      - UniProtKB:P9WHH9
      - UniProtKB:P27306
      - RGD:735073
      - UniProtKB:P0A9P0
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-07'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-07'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPAC1002.09c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0050660
  has_input:
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-07'
      provided_by:
      - http://www.pombase.org
    term: CHEBI:16238
- id: gomodel:67c10cc400001835/67c10cc400001855
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000641020
      - SGD:S000001396
      - MGI:MGI:1917156
      - UniProtKB:Q9H2D1
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-07'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-07'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPBC27B12.09c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0015230
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000255
      reference: GO_REF:0000050
      with_objects:
      - Pfam:PF00153
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-07'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-07'
      provided_by:
      - http://www.pombase.org
    term: GO:0005743
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000250
      reference: GO_REF:0000024
      with_objects:
      - UniProtKB:P40464
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-07'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-07'
      provided_by:
      - http://www.pombase.org
    term: GO:1990548
  has_input:
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000641020
      - SGD:S000001396
      - MGI:MGI:1917156
      - UniProtKB:Q9H2D1
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-07'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000641020
      - SGD:S000001396
      - MGI:MGI:1917156
      - UniProtKB:Q9H2D1
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-07'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-07'
      provided_by:
      - http://www.pombase.org
    term: CHEBI:16238
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-07'
      provided_by:
      - http://www.pombase.org
    term: CHEBI:16238
  has_output:
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-07'
      provided_by:
      - http://www.pombase.org
    term: CHEBI:16238
objects:
- id: GO:0008531
  label: riboflavin kinase activity
  type: gocam:Object
- id: PomBase:SPCC18.16c
  label: fmn1 Spom
  type: gocam:Object
- id: GO:0009398
  label: FMN biosynthetic process
  type: gocam:Object
- id: GO:0005829
  label: cytosol
  type: gocam:Object
- id: ECO:0000314
  label: direct assay evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: GO:0003919
  label: FMN adenylyltransferase activity
  type: gocam:Object
- id: PomBase:SPCC1235.04c
  label: nad1 Spom
  type: gocam:Object
- id: GO:0006747
  label: FAD biosynthetic process
  type: gocam:Object
- id: CHEBI:16238
  label: FAD
  type: gocam:Object
- id: CHEBI:58210
  label: FMN(3-)
  type: gocam:Object
- id: GO:0015230
  label: FAD transmembrane transporter activity
  type: gocam:Object
- id: PomBase:SPBC27B12.09c
  label: flx1 Spom
  type: gocam:Object
- id: GO:1990548
  label: mitochondrial FAD transmembrane transport
  type: gocam:Object
- id: GO:0005743
  label: mitochondrial inner membrane
  type: gocam:Object
- id: ECO:0000250
  label: sequence similarity evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000255
  label: match to sequence model evidence used in manual assertion
  type: gocam:Object
- id: GO:0005759
  label: mitochondrial matrix
  type: gocam:Object
- id: GO:0071949
  label: FAD binding
  type: gocam:Object
- id: PomBase:SPBC713.03
  label: dld2 Spom
  type: gocam:Object
- id: ECO:0000501
  label: evidence used in automatic assertion
  type: gocam:Object
- id: PomBase:SPAPB1A10.12c
  label: alo1 Spom
  type: gocam:Object
- id: PomBase:SPAC1F5.07c
  label: hem14 Spom
  type: gocam:Object
- id: GO:0050660
  label: flavin adenine dinucleotide binding
  type: gocam:Object
- id: PomBase:SPAC1556.02c
  label: sdh1 Spom
  type: gocam:Object
- id: GO:0005739
  label: mitochondrion
  type: gocam:Object
- id: PomBase:SPBC3B8.01c
  label: arh1 Spom
  type: gocam:Object
- id: PomBase:SPAC27D7.06
  label: etf1 Spom
  type: gocam:Object
- id: PomBase:SPCC70.03c
  label: put1 Spom
  type: gocam:Object
- id: PomBase:SPCC970.03
  label: cbr1 Spom
  type: gocam:Object
- id: PomBase:SPAC1296.06
  label: tah18 Spom
  type: gocam:Object
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: PomBase:SPBC30B4.06c
  label: ips1 Spom
  type: gocam:Object
- id: PomBase:SPAC1002.09c
  label: dld1 Spom
  type: gocam:Object
- id: PomBase:SPAC869.02c
  label: yhb1 Spom
  type: gocam:Object
- id: ECO:0000305
  label: curator inference used in manual assertion
  type: gocam:Object
- id: PomBase:SPBC146.12
  label: coq6 Spom
  type: gocam:Object
- id: ECO:0007005
  label: high throughput direct assay evidence used in manual assertion
  type: gocam:Object
- id: PomBase:SPBP35G2.07
  label: ilv1 Spom
  type: gocam:Object
- id: GO:0005741
  label: mitochondrial outer membrane
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0000-0001-6330-7526
  date: '2025-08-27'
  provided_by:
  - http://www.pombase.org
