id: gomodel:6690711d00000916
title: L-arginine biosynthetic process (GO:0006526)
taxon: NCBITaxon:4896
status: production
date_modified: '2025-08-27'
comments:
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645267/ shows that arg3 operates in
  mitochondira and cittruline is exported (unliek S. cerevisiae where ornithine is
  exported)
- https://www.researchgate.net/publication/370669123_Generation_of_a_Yeast_Cell_Model_Potentially_Useful_to_Identify_the_Mammalian_Mitochondrial_N-Acetylglutamate_Transporter/figures?lo=1
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objects:
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  label: mitochondrial membrane
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  label: author statement without traceable support used in manual assertion
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  label: biological aspect of ancestor evidence used in manual assertion
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  label: L-glutamate N-acetyltransferase activity
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  label: L-arginine biosynthetic process via ornithine
  type: gocam:Object
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  label: mitochondrial matrix
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- id: ECO:0000269
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  label: N-acetyl-gamma-glutamyl-phosphate reductase activity
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- id: ECO:0000314
  label: direct assay evidence used in manual assertion
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  label: acetylglutamate kinase activity
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- id: ECO:0000305
  label: curator inference used in manual assertion
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  label: N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
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- id: ECO:0000250
  label: sequence similarity evidence used in manual assertion
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    donor
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- id: CHEBI:15729
  label: L-ornithine
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  label: cytosol
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  label: high throughput direct assay evidence used in manual assertion
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  label: argininosuccinate lyase activity
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  label: L-citrulline zwitterion
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  label: L-arginine transmembrane transporter activity
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  label: protein
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- id: CHEBI:18366
  label: Arg-tRNA(Arg)
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  label: acetyl-CoA(4-)
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- id: PomBase:SPMITTRNAARG.01
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provenances:
- contributor:
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  date: '2025-08-27'
  provided_by:
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