id: gomodel:665912ed00002626
title: nitrogen cycle metabolic process (GO:0071941)
taxon: NCBITaxon:4896
status: production
date_modified: '2025-09-22'
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- id: gomodel:665912ed00002626/666b894f00001968
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000144486
      - TAIR:locus:2138743
      - TAIR:locus:2138718
      - CGD:CAL0000194495
      - UniProtKB:P60651
      - UniProtKB:Q5JI38
      provenances:
      - contributor:
        - https://orcid.org/0009-0003-9059-1333
        date: '2024-06-24'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2024-06-24'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPAC11D3.09
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0008783
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000305
      reference: GO_REF:0000111
      with_objects:
      - GO:0008783
      provenances:
      - contributor:
        - https://orcid.org/0009-0003-9059-1333
        date: '2024-06-24'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2024-06-24'
      provided_by:
      - http://www.pombase.org
    term: GO:0019627
  has_input:
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000144486
      - TAIR:locus:2138743
      - TAIR:locus:2138718
      - CGD:CAL0000194495
      - UniProtKB:P60651
      - UniProtKB:Q5JI38
      provenances:
      - contributor:
        - https://orcid.org/0009-0003-9059-1333
        date: '2024-06-24'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2024-06-24'
      provided_by:
      - http://www.pombase.org
    term: CHEBI:58145
  has_output:
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000144486
      - TAIR:locus:2138743
      - TAIR:locus:2138718
      - CGD:CAL0000194495
      - UniProtKB:P60651
      - UniProtKB:Q5JI38
      provenances:
      - contributor:
        - https://orcid.org/0009-0003-9059-1333
        date: '2024-06-24'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2024-06-24'
      provided_by:
      - http://www.pombase.org
    term: CHEBI:16199
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000144486
      - TAIR:locus:2138743
      - TAIR:locus:2138718
      - CGD:CAL0000194495
      - UniProtKB:P60651
      - UniProtKB:Q5JI38
      provenances:
      - contributor:
        - https://orcid.org/0009-0003-9059-1333
        date: '2025-04-07'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2025-04-07'
      provided_by:
      - http://www.pombase.org
    term: CHEBI:326268
objects:
- id: GO:0004038
  label: allantoinase activity
  type: gocam:Object
- id: CHEBI:36080
  label: protein
  type: gocam:Object
- id: GO:0019627
  label: urea metabolic process
  type: gocam:Object
- id: GO:0004087
  label: carbamoyl-phosphate synthase (ammonia) activity
  type: gocam:Object
- id: PomBase:SPBC215.08c
  label: arg4 Spom
  type: gocam:Object
- id: GO:0000050
  label: urea cycle
  type: gocam:Object
- id: ECO:0000501
  label: evidence used in automatic assertion
  type: gocam:Object
- id: ECO:0000305
  label: curator inference used in manual assertion
  type: gocam:Object
- id: PomBase:SPBC56F2.09c
  label: arg5 Spom
  type: gocam:Object
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: GO:0004585
  label: ornithine carbamoyltransferase activity
  type: gocam:Object
- id: PomBase:SPAC4G9.10
  label: arg3 Spom
  type: gocam:Object
- id: ECO:0000315
  label: mutant phenotype evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: GO:0004055
  label: argininosuccinate synthase activity
  type: gocam:Object
- id: PomBase:SPBC428.05c
  label: arg12 Spom
  type: gocam:Object
- id: GO:0004056
  label: argininosuccinate lyase activity
  type: gocam:Object
- id: PomBase:SPBC1539.03c
  label: arg41 Spom
  type: gocam:Object
- id: PomBase:SPBC1773.14
  label: arg7 Spom
  type: gocam:Object
- id: CHEBI:29806
  label: fumarate(2-)
  type: gocam:Object
- id: GO:0004053
  label: arginase activity
  type: gocam:Object
- id: PomBase:SPAC3H1.07
  label: aru1 Spom
  type: gocam:Object
- id: PomBase:SPBP26C9.02c
  label: car1 Spom
  type: gocam:Object
- id: ECO:0000316
  label: genetic interaction evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:16199
  label: urea
  type: gocam:Object
- id: GO:0009039
  label: urease activity
  type: gocam:Object
- id: PomBase:SPAC1952.11c
  label: ure2 Spom
  type: gocam:Object
- id: GO:0043419
  label: urea catabolic process
  type: gocam:Object
- id: ECO:0000269
  label: experimental evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000314
  label: direct assay evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:17775
  label: 7,9-dihydro-1H-purine-2,6,8(3H)-trione
  type: gocam:Object
- id: GO:0004846
  label: urate oxidase activity
  type: gocam:Object
- id: PomBase:SPCC1223.09
  label: uro1 Spom
  type: gocam:Object
- id: GO:0004037
  label: allantoicase activity
  type: gocam:Object
- id: PomBase:SPAC1F7.09c
  label: dal2 Spom
  type: gocam:Object
- id: CHEBI:28938
  label: ammonium
  type: gocam:Object
- id: GO:0008783
  label: agmatinase activity
  type: gocam:Object
- id: PomBase:SPAC11D3.09
  label: agm1 Spom
  type: gocam:Object
- id: CHEBI:58145
  label: agmatinium(2+)
  type: gocam:Object
- id: PomBase:SPAPB24D3.03
  label: agm2 Spom
  type: gocam:Object
- id: PomBase:SPBC8E4.03
  label: agm3 Spom
  type: gocam:Object
- id: CHEBI:18072
  label: 5-hydroxyisouric acid
  type: gocam:Object
- id: CHEBI:15678
  label: (S)-(+)-allantoin
  type: gocam:Object
- id: CHEBI:17536
  label: allantoate
  type: gocam:Object
- id: CHEBI:29991
  label: L-aspartate(1-)
  type: gocam:Object
- id: GO:0005829
  label: cytosol
  type: gocam:Object
- id: ECO:0007005
  label: high throughput direct assay evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:17544
  label: hydrogencarbonate
  type: gocam:Object
- id: CHEBI:43474
  label: hydrogenphosphate
  type: gocam:Object
- id: GO:0005739
  label: mitochondrion
  type: gocam:Object
- id: GO:0000064
  label: L-ornithine transmembrane transporter activity
  type: gocam:Object
- id: PomBase:SPBC29A3.11c
  label: ort1 Spom
  type: gocam:Object
- id: GO:1990575
  label: mitochondrial L-ornithine transmembrane transport
  type: gocam:Object
- id: GO:0005743
  label: mitochondrial inner membrane
  type: gocam:Object
- id: ECO:0000250
  label: sequence similarity evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:57743
  label: L-citrulline zwitterion
  type: gocam:Object
- id: GO:0005759
  label: mitochondrial matrix
  type: gocam:Object
- id: GO:0022857
  label: transmembrane transporter activity
  type: gocam:Object
- id: GO:0055085
  label: transmembrane transport
  type: gocam:Object
- id: CHEBI:16240
  label: hydrogen peroxide
  type: gocam:Object
- id: CHEBI:57296
  label: (-)-ureidoglycolate
  type: gocam:Object
- id: CHEBI:326268
  label: 1,4-butanediammonium
  type: gocam:Object
- id: GO:0004766
  label: spermidine synthase activity
  type: gocam:Object
- id: PomBase:SPBC12C2.07c
  label: srm1 Spom
  type: gocam:Object
- id: GO:0008295
  label: spermidine biosynthetic process
  type: gocam:Object
- id: CHEBI:57443
  label: S-adenosylmethioninaminium
  type: gocam:Object
- id: CHEBI:17509
  label: 5'-S-methyl-5'-thioadenosine
  type: gocam:Object
- id: CHEBI:57834
  label: spermidine(3+)
  type: gocam:Object
- id: CHEBI:46911
  label: L-ornithinium(1+)
  type: gocam:Object
- id: GO:0170061
  label: nickel chaperone activity
  type: gocam:Object
- id: GO:0150006
  label: urease activator complex
  type: gocam:Object
- id: ECO:0000304
  label: author statement supported by traceable reference used in manual assertion
  type: gocam:Object
- id: PomBase:SPAC3A12.09c
  label: ure4 Spom
  type: gocam:Object
- id: PomBase:SPAC29A4.13
  label: ure6 Spom
  type: gocam:Object
- id: PomBase:SPCPB16A4.05c
  label: ure7 Spom
  type: gocam:Object
- id: CHEBI:16467
  label: L-arginine
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0000-0001-6330-7526
  - https://orcid.org/0009-0003-9059-1333
  date: '2025-09-22'
  provided_by:
  - http://www.pombase.org
