id: gomodel:6870555700003085
title: pteridine-containing compound metabolic process (GO:0042558) - cytosolic
taxon: NCBITaxon:4896
status: production
activities:
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- id: gomodel:6870555700003085/6870555700003258
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    term: GO:0006729
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    evidence:
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      provided_by:
      - http://www.pombase.org
    term: CHEBI:43120
- id: gomodel:6870555700003085/6870555700003265
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    term: CHEBI:36080
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      - http://www.pombase.org
    term: GO:0005829
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    evidence: []
    provenances:
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      - https://orcid.org/0009-0003-9059-1333
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    term: GO:0006729
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      - http://www.pombase.org
    term: CHEBI:58462
  has_output:
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    term: CHEBI:136564
objects:
- id: GO:0004372
  label: glycine hydroxymethyltransferase activity
  type: gocam:Object
- id: CHEBI:36080
  label: protein
  type: gocam:Object
- id: GO:0046653
  label: tetrahydrofolate metabolic process
  type: gocam:Object
- id: CHEBI:57453
  label: (6S)-5,6,7,8-tetrahydrofolate(2-)
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: GO:0005829
  label: cytosol
  type: gocam:Object
- id: GO:0004146
  label: dihydrofolate reductase activity
  type: gocam:Object
- id: PomBase:SPCC1223.08c
  label: dfr1 Spom
  type: gocam:Object
- id: GO:0046655
  label: folic acid metabolic process
  type: gocam:Object
- id: ECO:0000316
  label: genetic interaction evidence used in manual assertion
  type: gocam:Object
- id: GO:0004488
  label: methylenetetrahydrofolate dehydrogenase (NADP+) activity
  type: gocam:Object
- id: PomBase:SPBC2G2.08
  label: ade9 Spom
  type: gocam:Object
- id: GO:0009257
  label: 10-formyltetrahydrofolate biosynthetic process
  type: gocam:Object
- id: ECO:0000250
  label: sequence similarity evidence used in manual assertion
  type: gocam:Object
- id: GO:0004477
  label: methenyltetrahydrofolate cyclohydrolase activity
  type: gocam:Object
- id: PomBase:SPBC839.16
  label: thf1 Spom
  type: gocam:Object
- id: ECO:0000314
  label: direct assay evidence used in manual assertion
  type: gocam:Object
- id: ECO:0007005
  label: high throughput direct assay evidence used in manual assertion
  type: gocam:Object
- id: GO:0004487
  label: methylenetetrahydrofolate dehydrogenase (NAD+) activity
  type: gocam:Object
- id: PomBase:SPBC1711.04
  label: mtd1 Spom
  type: gocam:Object
- id: GO:0046656
  label: folic acid biosynthetic process
  type: gocam:Object
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: GO:0004489
  label: methylenetetrahydrofolate reductase [NAD(P)H] activity
  type: gocam:Object
- id: PomBase:SPAC56F8.10
  label: met9 Spom
  type: gocam:Object
- id: GO:0035999
  label: tetrahydrofolate interconversion
  type: gocam:Object
- id: ECO:0000315
  label: mutant phenotype evidence used in manual assertion
  type: gocam:Object
- id: PomBase:SPAC343.10
  label: met11 Spom
  type: gocam:Object
- id: GO:0004326
  label: tetrahydrofolylpolyglutamate synthase activity
  type: gocam:Object
- id: PomBase:SPBC1709.17
  label: met7 Spom
  type: gocam:Object
- id: GO:0046901
  label: tetrahydrofolylpolyglutamate biosynthetic process
  type: gocam:Object
- id: PomBase:SPAC227.09
  label: fol3 Spom
  type: gocam:Object
- id: ECO:0000501
  label: evidence used in automatic assertion
  type: gocam:Object
- id: GO:0004329
  label: formate-tetrahydrofolate ligase activity
  type: gocam:Object
- id: GO:0003934
  label: GTP cyclohydrolase I activity
  type: gocam:Object
- id: PomBase:SPAC17A5.13
  label: fol2 Spom
  type: gocam:Object
- id: GO:0046654
  label: tetrahydrofolate biosynthetic process
  type: gocam:Object
- id: GO:0008841
  label: dihydrofolate synthase activity
  type: gocam:Object
- id: GO:0009396
  label: folic acid-containing compound biosynthetic process
  type: gocam:Object
- id: GO:0004156
  label: dihydropteroate synthase activity
  type: gocam:Object
- id: PomBase:SPBC1734.03
  label: fol1 Spom
  type: gocam:Object
- id: GO:0008696
  label: 4-amino-4-deoxychorismate lyase activity
  type: gocam:Object
- id: PomBase:SPBC19G7.02
  label: abz2 Spom
  type: gocam:Object
- id: GO:0046820
  label: 4-amino-4-deoxychorismate synthase activity
  type: gocam:Object
- id: PomBase:SPBP8B7.29
  label: abz1 Spom
  type: gocam:Object
- id: CHEBI:29748
  label: chorismate(2-)
  type: gocam:Object
- id: GO:0004757
  label: sepiapterin reductase (NADP+) activity
  type: gocam:Object
- id: PomBase:SPBC30D10.05c
  label: nre1 Spom
  type: gocam:Object
- id: GO:0006729
  label: tetrahydrobiopterin biosynthetic process
  type: gocam:Object
- id: CHEBI:15642
  label: 4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin
  type: gocam:Object
- id: GO:0008124
  label: 4-alpha-hydroxytetrahydrobiopterin dehydratase activity
  type: gocam:Object
- id: PomBase:SPAC27D7.04
  label: omt2 Spom
  type: gocam:Object
- id: CHEBI:43120
  label: (6R)-L-erythro-6,7-dihydrobiopterin
  type: gocam:Object
- id: GO:0003874
  label: 6-pyruvoyltetrahydropterin synthase activity
  type: gocam:Object
- id: CHEBI:58462
  label: 7,8-dihydroneopterin 3'-triphosphate(4-)
  type: gocam:Object
- id: CHEBI:136564
  label: (R)-dyspropterin
  type: gocam:Object
- id: GO:0004644
  label: phosphoribosylglycinamide formyltransferase activity
  type: gocam:Object
- id: PomBase:SPCC569.08c
  label: ade5 Spom
  type: gocam:Object
- id: GO:0006189
  label: '''de novo'' IMP biosynthetic process'
  type: gocam:Object
- id: CHEBI:195366
  label: (6R)-10-formyltetrahydrofolate(2-)
  type: gocam:Object
- id: GO:0004643
  label: phosphoribosylaminoimidazolecarboxamide formyltransferase activity
  type: gocam:Object
- id: PomBase:SPCPB16A4.03c
  label: ade10 Spom
  type: gocam:Object
- id: CHEBI:143788
  label: N(1)-(5-phospho-beta-D-ribosyl)glycinamide(1-)
  type: gocam:Object
- id: CHEBI:147286
  label: N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide(2-)
  type: gocam:Object
- id: CHEBI:58475
  label: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide(2-)
  type: gocam:Object
- id: CHEBI:58467
  label: 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide(2-)
  type: gocam:Object
- id: CHEBI:58359
  label: L-glutamine zwitterion
  type: gocam:Object
- id: CHEBI:29985
  label: L-glutamate(1-)
  type: gocam:Object
- id: CHEBI:15361
  label: pyruvate
  type: gocam:Object
- id: CHEBI:72950
  label: (7,8-dihydropterin-6-yl)methyl diphosphate(3-)
  type: gocam:Object
- id: CHEBI:33384
  label: L-serine zwitterion
  type: gocam:Object
- id: CHEBI:57305
  label: glycine zwitterion
  type: gocam:Object
- id: CHEBI:15636
  label: (6R)-5,10-methylenetetrahydrofolate(2-)
  type: gocam:Object
- id: CHEBI:18608
  label: (6S)-5-methyltetrahydrofolate(2-)
  type: gocam:Object
- id: CHEBI:141005
  label: (6S)-5,6,7,8-tetrahydrofolyl-poly(gamma-glutamate) macromolecule
  type: gocam:Object
- id: CHEBI:57455
  label: (6R)-5,10-methenyltetrahydrofolate
  type: gocam:Object
- id: CHEBI:15740
  label: formate
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0009-0003-9059-1333
  date: '2025-07-21'
  provided_by:
  - http://www.pombase.org
