id: gomodel:67369e7600004623
title: aromatic amino acid biosynthetic process (GO:0009073)
taxon: NCBITaxon:4896
status: production
comments:
- 'source: https://www.researchgate.net/publication/237086259_Shikimate_pathway_in_yeast_cells_Enzymes_functioning_regulation_-_A_review/figures'
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    term: PomBase:SPAC1834.02
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    term: GO:0004764
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    evidence:
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      provenances:
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    term: GO:0005829
  part_of:
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    evidence:
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      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000472635
      - TAIR:locus:2050812
      - UniProtKB:P9WPY5
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    term: GO:0009423
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    term: CHEBI:16630
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    evidence: []
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    term: CHEBI:36208
- id: gomodel:67369e7600004623/67369e7600004624
  enabled_by:
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    evidence:
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      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000476971
      - UniProtKB:P00887
      - UniProtKB:P0AB91
      - UniProtKB:P00888
      - CGD:CAL0000182853
      - CGD:CAL0000176586
      - SGD:S000000453
      - UniProtKB:C8VTT5
      - SGD:S000002442
      - UniProtKB:G5EB34
      provenances:
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    provenances:
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      date: '2024-12-06'
      provided_by:
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    term: PomBase:SPAC24H6.10c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0003849
  occurs_in:
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    evidence:
    - term: ECO:0007005
      reference: '

        PMID:16823372'
      provenances:
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    provenances:
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      date: '2024-12-06'
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      - http://www.pombase.org
    term: GO:0005829
  part_of:
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    evidence:
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      reference: GO_REF:0000111
      with_objects:
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    term: GO:0009423
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    evidence:
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      reference: GO_REF:0000033
      with_objects:
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      - CGD:CAL0000182853
      - CGD:CAL0000176586
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      provenances:
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      - http://www.pombase.org
    term: CHEBI:58394
- id: gomodel:67369e7600004623/67369e7600004761
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    evidence:
    - term: ECO:0000315
      reference: PMID:24186364
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      - contributor:
        - https://orcid.org/0000-0001-6330-7526
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      - https://orcid.org/0000-0001-6330-7526
      date: '2024-12-07'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPBC1539.09c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0004425
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    type: CellularAnatomicalEntityAssociation
    evidence:
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      reference: PMID:16823372
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      date: '2024-12-07'
      provided_by:
      - http://www.pombase.org
    term: GO:0005829
  part_of:
    type: BiologicalProcessAssociation
    evidence:
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      reference: PMID:24186364
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
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        provided_by:
        - http://www.pombase.org
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
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      - UniProtKB:P20576
      - UniProtKB:Q764B9
      - PomBase:SPBC1539.09c
      - UniProtKB:P00904
      - UniProtKB:P28819
      - TAIR:locus:2033025
      - UniProtKB:Q7XUS2
      - SGD:S000001694
      provenances:
      - contributor:
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      - https://orcid.org/0000-0001-6330-7526
      date: '2024-12-07'
      provided_by:
      - http://www.pombase.org
    term: GO:0000162
  has_input:
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    evidence:
    - term: ECO:0000315
      reference: PMID:24186364
      provenances:
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        - https://orcid.org/0000-0001-6330-7526
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    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2024-12-07'
      provided_by:
      - http://www.pombase.org
    term: CHEBI:58613
  has_output:
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2024-12-07'
      provided_by:
      - http://www.pombase.org
    term: CHEBI:58866
objects:
- id: GO:0004664
  label: prephenate dehydratase activity
  type: gocam:Object
- id: PomBase:SPBC30D10.16
  label: pha2 Spom
  type: gocam:Object
- id: GO:0009094
  label: L-phenylalanine biosynthetic process
  type: gocam:Object
- id: GO:0005829
  label: cytosol
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000315
  label: mutant phenotype evidence used in manual assertion
  type: gocam:Object
- id: ECO:0007005
  label: high throughput direct assay evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:18005
  label: keto-phenylpyruvate
  type: gocam:Object
- id: GO:0080130
  label: L-phenylalanine-2-oxoglutarate transaminase activity
  type: gocam:Object
- id: PomBase:SPAC56E4.03
  label: SPAC56E4.03 Spom
  type: gocam:Object
- id: ECO:0000501
  label: evidence used in automatic assertion
  type: gocam:Object
- id: ECO:0000305
  label: curator inference used in manual assertion
  type: gocam:Object
- id: CHEBI:58095
  label: L-phenylalanine zwitterion
  type: gocam:Object
- id: GO:0008977
  label: prephenate dehydrogenase (NAD+) activity
  type: gocam:Object
- id: PomBase:SPCC1494.04c
  label: tyr1 Spom
  type: gocam:Object
- id: GO:0006571
  label: tyrosine biosynthetic process
  type: gocam:Object
- id: ECO:0000269
  label: experimental evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:36242
  label: 3-(4-hydroxyphenyl)pyruvate
  type: gocam:Object
- id: GO:0004838
  label: L-tyrosine-2-oxoglutarate transaminase activity
  type: gocam:Object
- id: ECO:0000303
  label: author statement without traceable support used in manual assertion
  type: gocam:Object
- id: CHEBI:58315
  label: L-tyrosine zwitterion
  type: gocam:Object
- id: GO:0004422
  label: hypoxanthine phosphoribosyltransferase activity
  type: gocam:Object
- id: PomBase:SPAC23C11.13c
  label: hpt1 Spom
  type: gocam:Object
- id: GO:0046100
  label: hypoxanthine metabolic process
  type: gocam:Object
- id: ECO:0000314
  label: direct assay evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:58702
  label: phosphonatoenolpyruvate
  type: gocam:Object
- id: CHEBI:16897
  label: D-erythrose 4-phosphate(2-)
  type: gocam:Object
- id: GO:0015171
  label: amino acid transmembrane transporter activity
  type: gocam:Object
- id: CHEBI:36080
  label: protein
  type: gocam:Object
- id: GO:0015823
  label: phenylalanine transport
  type: gocam:Object
- id: GO:0005743
  label: mitochondrial inner membrane
  type: gocam:Object
- id: GO:0015173
  label: aromatic amino acid transmembrane transporter activity
  type: gocam:Object
- id: GO:1904556
  label: L-tryptophan transmembrane transport
  type: gocam:Object
- id: GO:0004830
  label: tryptophan-tRNA ligase activity
  type: gocam:Object
- id: PomBase:SPAC3G9.13c
  label: msw1 Spom
  type: gocam:Object
- id: GO:0043038
  label: amino acid activation
  type: gocam:Object
- id: GO:0005759
  label: mitochondrial matrix
  type: gocam:Object
- id: CHEBI:57912
  label: L-tryptophan zwitterion
  type: gocam:Object
- id: GO:0004826
  label: phenylalanine-tRNA ligase activity
  type: gocam:Object
- id: PomBase:SPCC736.03c
  label: msf1 Spom
  type: gocam:Object
- id: GO:0005302
  label: L-tyrosine transmembrane transporter activity
  type: gocam:Object
- id: GO:0015828
  label: tyrosine transport
  type: gocam:Object
- id: GO:0004831
  label: tyrosine-tRNA ligase activity
  type: gocam:Object
- id: PomBase:SPCC576.06c
  label: SPCC576.06c Spom
  type: gocam:Object
- id: GO:0043039
  label: tRNA aminoacylation
  type: gocam:Object
- id: CHEBI:29153
  label: Phe-tRNA(Phe)
  type: gocam:Object
- id: PomBase:SPMITTRNAPHE.01
  label: SPMITTRNAPHE.01 Spom
  type: gocam:Object
- id: CHEBI:29159
  label: Trp-tRNA(Trp)
  type: gocam:Object
- id: PomBase:SPMITTRNATRP.01
  label: SPMITTRNATRP.01 Spom
  type: gocam:Object
- id: GO:0003849
  label: 3-deoxy-7-phosphoheptulonate synthase activity
  type: gocam:Object
- id: PomBase:SPAC24H6.10c
  label: aro4 Spom
  type: gocam:Object
- id: GO:0009423
  label: chorismate biosynthetic process
  type: gocam:Object
- id: PomBase:SPAP8A3.07c
  label: aro3 Spom
  type: gocam:Object
- id: CHEBI:58394
  label: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate
  type: gocam:Object
- id: GO:0004107
  label: chorismate synthase activity
  type: gocam:Object
- id: PomBase:SPCC1223.14
  label: aro2 Spom
  type: gocam:Object
- id: GO:0003855
  label: 3-dehydroquinate dehydratase activity
  type: gocam:Object
- id: PomBase:SPAC1834.02
  label: aro1 Spom
  type: gocam:Object
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: GO:0003856
  label: 3-dehydroquinate synthase activity
  type: gocam:Object
- id: GO:0003866
  label: 3-phosphoshikimate 1-carboxyvinyltransferase activity
  type: gocam:Object
- id: GO:0004764
  label: shikimate 3-dehydrogenase (NADP+) activity
  type: gocam:Object
- id: GO:0004765
  label: shikimate kinase activity
  type: gocam:Object
- id: CHEBI:32364
  label: 3-dehydroquinate
  type: gocam:Object
- id: CHEBI:16630
  label: 3-dehydroshikimate
  type: gocam:Object
- id: CHEBI:36208
  label: shikimate
  type: gocam:Object
- id: CHEBI:145989
  label: 3-phosphonatoshikimate(3-)
  type: gocam:Object
- id: CHEBI:57701
  label: 5-O-(1-carboxylatovinyl)-3-phosphonatoshikimate
  type: gocam:Object
- id: CHEBI:29748
  label: chorismate(2-)
  type: gocam:Object
- id: GO:0004106
  label: chorismate mutase activity
  type: gocam:Object
- id: PomBase:SPAC16E8.04c
  label: aro7 Spom
  type: gocam:Object
- id: CHEBI:29934
  label: (1s,4s)-prephenate(2-)
  type: gocam:Object
- id: GO:0004049
  label: anthranilate synthase activity
  type: gocam:Object
- id: PomBase:SPCC1442.09
  label: trp3 Spom
  type: gocam:Object
- id: GO:0000162
  label: L-tryptophan biosynthetic process
  type: gocam:Object
- id: CHEBI:18050
  label: L-glutamine
  type: gocam:Object
- id: CHEBI:16567
  label: anthranilate
  type: gocam:Object
- id: CHEBI:15361
  label: pyruvate
  type: gocam:Object
- id: CHEBI:29985
  label: L-glutamate(1-)
  type: gocam:Object
- id: GO:0004048
  label: anthranilate phosphoribosyltransferase activity
  type: gocam:Object
- id: PomBase:SPBC16G5.08
  label: trp4 Spom
  type: gocam:Object
- id: CHEBI:58017
  label: 5-O-phosphonato-alpha-D-ribofuranosyl diphosphate(5-)
  type: gocam:Object
- id: GO:0004425
  label: indole-3-glycerol-phosphate synthase activity
  type: gocam:Object
- id: PomBase:SPBC1539.09c
  label: trp1 Spom
  type: gocam:Object
- id: CHEBI:18277
  label: N-(5-phosphonato-beta-D-ribosyl)anthranilate
  type: gocam:Object
- id: GO:0004640
  label: phosphoribosylanthranilate isomerase activity
  type: gocam:Object
- id: CHEBI:58613
  label: 1-(2-carboxylatophenylamino)-1-deoxy-D-ribulose 5-phosphate(3-)
  type: gocam:Object
- id: CHEBI:58866
  label: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate(2-)
  type: gocam:Object
- id: GO:0004834
  label: tryptophan synthase activity
  type: gocam:Object
- id: PomBase:SPAC19A8.15
  label: trp2 Spom
  type: gocam:Object
- id: CHEBI:17115
  label: L-serine
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0000-0001-6330-7526
  date: '2025-04-23'
  provided_by:
  - http://www.pombase.org
