ID   X54421     standard; circular DNA; ORG; 19431 BP.
XX
AC   X54421;
XX
SV   X54421.1
XX
DT   28-NOV-1990 (Rel. 26, Created)
DT   14-MAR-2001 (Rel. 67, Last updated, Version 13)
XX
DE   Schizosaccharomyces pombe complete mitochondrial genome
XX
KW   apocytochrome b; ATPase; cob gene; cox gene; cytochrome b;
KW   cytochrome oxidase; large ribosomal RNA; mitochondrial genome; oxidase;
KW   ribosomal DNA; ribosomal RNA; small ribosomal RNA; transfer RNA.
XX
OS   Schizosaccharomyces pombe (fission yeast)
OC   Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes;
OC   Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
OG   Mitochondrion
XX
RN   [1]
RP   1-19431
RA   Lang B.F.;
RT   ;
RL   Submitted (16-AUG-1990) to the EMBL/GenBank/dictyBaseJ databases.
RL   Lang B.F., Departement de Biochemie, Universite de Montreal, C.P. 6128 ,
RL   Montreal, Quebec H3C 3J7, Canada.
XX
RN   [2]
RP   1-2900
RX   MEDLINE; 88082786.
RA   Lang B.F., Cedergren R.J., Gray M.W.;
RT   "The mitochondrial genome of the fission yeast, Schizosaccharomyces pombe.
RT   Sequence of the large.subunit ribosomal RNA gene, comparison of potential
RT   secondary structure in fungal mitochondrial large.subunit rRNAs and
RT   evolutionary considerations";
RL   Eur. J. Biochem. 169:527-537(1987).
XX
RN   [3]
RP   3131-4580
RX   MEDLINE; 89386004.
RA   Trinkl H., Lang B.F., Wolf K.;
RT   "Nucleotide sequence of the gene encoding the small ribosomal RNA in the
RT   mitochondrial genome of the fission yeast Schizosaccharomyces pombe";
RL   Nucleic Acids Res. 17:6730-6730(1989).
XX
RN   [4]
RP   4666-8923
RX   MEDLINE; 85027166.
RA   Lang B.F.;
RT   "The mitochondrial genome of the fission yeast Schizosaccharomyces pombe:
RT   IV. Highly homologous introns are inserted at the same position of the
RT   otherwise less conserved cox1 genes in Schizosaccharomyces pombe and
RT   Aspergillus nidulans";
RL   EMBO J. 3:2129-2136(1984).
XX
RN   [5]
RP   9973-13974
RX   MEDLINE; 86011547.
RA   Lang B.F., Ahne F., Bonen L.;
RT   "The mitochondrial genome of the fission yeast Schizosaccharomyces pombe:
RT   The cytochrome b gene has an intron closely related to the first two
RT   introns in the Saccharomyces cerevisiae cox1 gene";
RL   J. Mol. Biol. 184:353-366(1985).
XX
RN   [6]
RP   14275-14508, 15464-15629
RA   Lang B.F., Ahne F., Distler S., Trinkl H., Kaudewitz F., Wolf K.;
RT   ;
RL   Unpublished.
XX
DR   SWISS-PROT; P05501; CYB_SCHPO.
DR   SWISS-PROT; P05511; YM91_SCHPO.
DR   SWISS-PROT; P07657; COX1_SCHPO.
DR   SWISS-PROT; P14575; COX3_SCHPO.
DR   SWISS-PROT; P21534; COX2_SCHPO.
DR   SWISS-PROT; P21535; ATP6_SCHPO.
DR   SWISS-PROT; P21536; ATP8_SCHPO.
DR   SWISS-PROT; P21537; ATP9_SCHPO.
DR   SWISS-PROT; P21547; YM25_SCHPO.
DR   SWISS-PROT; P22190; YMC2_SCHPO.
DR   SWISS-PROT; P22191; YMC1_SCHPO.
XX
CC   See <X06597> for overlapping sequence ([2]).
XX
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..19431
FT                   /db_xref="taxon:4896"
FT                   /organelle=mitochondrion
FT                   /organism="Schizosaccharomyces pombe"
FT                   /allele="ad7-50h-."
FT   rRNA            1..2822
FT                   /product="21S rRNA"
FT                   /gene="21S_rRNA"
FT                   /primary_name="21S_rRNA"
FT                   /systematic_id="SPRRNA.01"
FT   misc_difference complement(2091)
FT                   /note="conflict"
FT                   /replace="c"
FT                   /db_xref="PMID:2446871"
FT   tRNA            2857..2929
FT                   /gene="SPMITTRNALYS.01"
FT                   /product="tRNA Lysine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033443;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=AAA codon-amino acid adaptor activity;
FT                   GOid=GO:0033443; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20150206"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033443; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNALYS.01"
FT   tRNA            2968..3050
FT                   /gene="SPMITTRNASER.01"
FT                   /product="tRNA Serine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033446;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=AGC codon-amino acid adaptor activity;
FT                   GOid=GO:0033446; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20150206"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033446; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNASER.01"
FT   tRNA            3060..3130
FT                   /gene="SPMITTRNAASN.01"
FT                   /product="tRNA Asparagine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033442;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=AAC codon-amino acid adaptor activity;
FT                   GOid=GO:0033442; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20150206"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033442; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNAASN.01"
FT   rRNA            3131..4552
FT                   /product="15S rRNA"
FT                   /gene="15S_rRNA"
FT                   /primary_name="15S_rRNA"
FT                   /systematic_id="SPRRNA.02"
FT   misc_difference complement(4102)
FT                   /note="conflict"
FT                   /replace="g"
FT                   /db_xref="PMID:2780299"
FT   tRNA            4591..4665
FT                   /gene="SPMITTRNAMET.01"
FT                   /product="tRNA Methionine, mitochondrial"
FT                   /GO="aspect=P; term=translation; GOid=GO:0006412;
FT                   evidence=ISM; from=GO:0033436; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /GO="aspect=F; term=ATG codon-amino acid adaptor activity;
FT                   GOid=GO:0033436; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20070713"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033436; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNAMET.01"
FT   CDS             join(4886..5289,6500..6844,7926..8790)
FT                   /transl_table=4
FT                   /gene="cox1"
FT                   /primary_name="cox1"
FT                   /systematic_id="SPMIT.01"
FT                   /product="cytochrome c oxidase 1 (predicted)"
FT                   /colour=2
FT                   /GO="aspect=C; term=respiratory chain complex IV (sensu
FT                   Eukaryota); GOid=GO:0005751; evidence=ISS;
FT                   db_xref=GO_REF:0000024; with=SGD:S000007260;
FT                   date=20040629"
FT                   /GO="aspect=F; term=cytochrome-c oxidase activity;
FT                   GOid=GO:0004129; evidence=ISS; db_xref=GO_REF:0000024;
FT                   with=SGD:S000007260; date=20040629"
FT                   /GO="aspect=P; term=aerobic respiration; GOid=GO:0009060;
FT                   evidence=ISS; db_xref=GO_REF:0000024; with=SGD:S000007260;
FT                   date=20040629"
FT                   /GO="aspect=P; term=mitochondrial electron transport,
FT                   cytochrome c to oxygen; GOid=GO:0006123; evidence=ISS;
FT                   db_xref=GO_REF:0000024; with=SGD:S000007260;
FT                   date=20160216"
FT                   /fasta_file="fasta/pMIT.tab.seq.00048.out"
FT                   /controlled_curation="term=orthologous to S. cerevisiae
FT                   Q0045; date=20070727"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in bacteria; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in fungi; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in eukaryotes; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in metazoa; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in vertebrates; date=20100820"
FT                   /controlled_curation="term=species distribution,
FT                   predominantly single copy (one to one); date=20100820"
FT   intron          5290..6499
FT                   /systematic_id="SPMIT.01"
FT   CDS             5291..6445
FT                   /systematic_id="SPMIT.02"
FT                   /product="mitochondrial DNA binding endonuclease
FT                   (predicted)"
FT                   /transl_table=4
FT                   /colour=7
FT                   /fasta_file="fasta/pMIT.tab.seq.00049.out"
FT                   /GO="aspect=P; term=intron homing; GOid=GO:0006314;
FT                   evidence=ISM; db_xref=GO_REF:0000050; with=Pfam:PF00961;
FT                   date=20060209"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; db_xref=GO_REF:0000111; from=GO:0006314;
FT                   date=20060209"
FT                   /GO="aspect=F; term=DNA binding; GOid=GO:0003677;
FT                   evidence=ISM; db_xref=GO_REF:0000050; with=Pfam:PF00961;
FT                   date=20060209"
FT                   /GO="aspect=F; term=endonuclease activity;
FT                   GOid=GO:0004519; evidence=ISM; db_xref=GO_REF:0000050;
FT                   with=Pfam:PF00961; date=20060209"
FT                   /controlled_curation="term=genome organization, protein in
FT                   cox1 intron-1; cv=genome_org; date=20070727"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in fungi; date=20100827"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in eukaryotes; date=20100827"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in archaea; date=20100827"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in metazoa; date=20100827"
FT                   /controlled_curation="term=species distribution,
FT                   predominantly single copy (one to one); date=20100827"
FT                   /controlled_curation="term=orthologous to S. cerevisiae
FT                   Q0110 and Q0115 and Q0120 and Q0255; date=20110719"
FT                   /controlled_curation="term=warning, intronic ORF;
FT                   date=20110719"
FT   intron          6845..7925
FT                   /systematic_id="SPMIT.01"
FT   CDS             <6966..7718
FT                   /systematic_id="SPMIT.03"
FT                   /product="mitochondrial DNA binding endonuclease
FT                   (predicted)"
FT                   /transl_table=4
FT                   /colour=7
FT                   /fasta_file="fasta/pMIT.tab.seq.00050.out"
FT                   /GO="aspect=P; term=intron homing; GOid=GO:0006314;
FT                   evidence=ISM; db_xref=GO_REF:0000050; with=Pfam:PF00961;
FT                   date=20060209"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; db_xref=GO_REF:0000024; from=GO:0006314;
FT                   date=20060209"
FT                   /GO="aspect=F; term=DNA binding; GOid=GO:0003677;
FT                   evidence=ISM; db_xref=GO_REF:0000050; with=Pfam:PF00961;
FT                   date=20060209"
FT                   /GO="aspect=F; term=endonuclease activity;
FT                   GOid=GO:0004519; evidence=ISM; db_xref=GO_REF:0000050;
FT                   with=Pfam:PF00961; date=20060209"
FT                   /controlled_curation="term=gene expression, RNA level;
FT                   annotation_extension=during(GO:0034605);
FT                   qualifier=increased; evidence=ECO:0000058;
FT                   db_xref=PMID:12529438; date=20130503"
FT                   /controlled_curation="term=genome organization, protein in
FT                   cox1 intron-2; cv=genome_org; date=20070727"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in fungi; date=20100827"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in eukaryotes; date=20100827"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in archaea; date=20100827"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in metazoa; date=20100827"
FT                   /controlled_curation="term=species distribution,
FT                   predominantly single copy (one to one); date=20100827"
FT                   /controlled_curation="term=orthologous to S. cerevisiae
FT                   Q0060 and Q0065 and Q0075; date=20110719"
FT                   /controlled_curation="term=warning, intronic ORF;
FT                   date=20110719"
FT   CDS             8947..9765
FT                   /EC_number="1.9.3.1"
FT                   /gene="cox3"
FT                   /primary_name="cox3"
FT                   /systematic_id="SPMIT.04"
FT                   /product="cytochrome c oxidase 3"
FT                   /colour=2
FT                   /GO="aspect=C; term=respiratory chain complex IV (sensu
FT                   Eukaryota); GOid=GO:0005751; evidence=ISS;
FT                   db_xref=GO_REF:0000024; with=SGD:S000007283;
FT                   date=20040629"
FT                   /transl_table=4
FT                   /controlled_curation="term=orthologous to S. cerevisiae
FT                   Q0275; date=20070727"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in bacteria; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in fungi; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in eukaryotes; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in metazoa; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in vertebrates; date=20100820"
FT                   /controlled_curation="term=species distribution,
FT                   predominantly single copy (one to one); date=20100820"
FT   tRNA            9818..9894
FT                   /gene="SPMITTRNAARG.01"
FT                   /product="tRNA Arginine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033447;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=AGA codon-amino acid adaptor activity;
FT                   GOid=GO:0033447; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20150206"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033447; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNAARG.01"
FT   tRNA            9920..9992
FT                   /note="anticodon=ugu, thr"
FT                   /gene="SPMITTRNATHR.01"
FT                   /systematic_id="SPMITTRNATHR.01"
FT                   /product="tRNA Threonine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033439;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=ACA codon-amino acid adaptor activity;
FT                   GOid=GO:0033439; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20150206"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033439; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT   CDS             join(10173..10856,13383..13862)
FT                   /transl_table=4
FT                   /gene="cob1"
FT                   /gene="cob"
FT                   /gene="SPMIT.05"
FT                   /primary_name="cob1"
FT                   /synonym="cob"
FT                   /synonym="cytb"
FT                   /systematic_id="SPMIT.05"
FT                   /product="cytochrome b, Cob1 (predicted)"
FT                   /colour=7
FT                   /GO="aspect=C; term=mitochondrial respiratory chain
FT                   complex III; GOid=GO:0005750; evidence=TAS;
FT                   db_xref=PMID:6094974; date=20040505"
FT                   /GO="aspect=F; term=ubiquinol-cytochrome-c reductase
FT                   activity; GOid=GO:0008121; evidence=TAS;
FT                   db_xref=PMID:6094974; date=20040505"
FT                   /GO="aspect=P; term=mitochondrial electron transport,
FT                   ubiquinol to cytochrome c; GOid=GO:0006122; evidence=TAS;
FT                   db_xref=PMID:6094974; date=20040505"
FT                   /controlled_curation="term=orthologous to S. cerevisiae
FT                   Q0105; date=20070727"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in eukaryotes; date=20070727"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in bacteria; date=20070727"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in metazoa; date=20090507"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in vertebrates; date=20090507"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in fungi; date=20140321"
FT                   /controlled_curation="term=disease associated, metabolic
FT                   disorders; date=20160106"
FT                   /controlled_curation="term=disease associated,
FT                   mitochondrial disorders; date=20160106"
FT                   /controlled_curation="term=disease associated,
FT                   mitochondrial complex III deficiency; date=20160106"
FT   CDS             10857..13280
FT                   /note="intronic ORF"
FT                   /transl_table=4
FT                   /systematic_id="SPMIT.06"
FT                   /product="mitochondrial DNA binding endonuclease
FT                   (predicted)"
FT                   /colour=7
FT                   /fasta_file="fasta/pMIT.tab.seq.00053.out"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=ISS; db_xref=GO_REF:0000024; with=SGD:S000007261;
FT                   date=20040906"
FT                   /GO="aspect=F; term=DNA binding; GOid=GO:0003677;
FT                   evidence=ISS; db_xref=GO_REF:0000024; with=SGD:S000007261;
FT                   date=20040906"
FT                   /GO="aspect=F; term=endonuclease activity;
FT                   GOid=GO:0004519; evidence=ISS; db_xref=GO_REF:0000024;
FT                   with=SGD:S000007261; date=20040906"
FT                   /GO="aspect=P; term=homing of group II introns;
FT                   GOid=GO:0006315; evidence=ISS; db_xref=GO_REF:0000024;
FT                   with=SGD:S000007261; date=20040906"
FT                   /controlled_curation="term=genome organization, protein in
FT                   cob intron; cv=genome_org; date=20070727"
FT                   /controlled_curation="term=orthologous to S. cerevisiae
FT                   Q0050 and Q0055; date=20070727"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in fungi; date=20070727"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in bacteria; date=20070727"
FT   intron          10857..13382
FT                   /systematic_id="SPMIT.05"
FT   tRNA            14081..14153
FT                   /gene="SPMITTRNAMET.02"
FT                   /product="tRNA Methionine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033436;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=ATG codon-amino acid adaptor activity;
FT                   GOid=GO:0033436; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20070713"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033436; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNAMET.02"
FT   tRNA            14159..14230
FT                   /gene="SPMITTRNAPHE.01"
FT                   /product="tRNA Phenylalanine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033402;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=UUC codon-amino acid adaptor activity;
FT                   GOid=GO:0033402; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20150206"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033402; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNAPHE.01"
FT   tRNA            14238..14308
FT                   /gene="SPMITTRNAASP.01"
FT                   /product="tRNA Aspartic acid, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033458;
FT                   db_xref=GO_REF:0000050; date=20070713"
FT                   /GO="aspect=F; term=GAC codon-amino acid adaptor activity;
FT                   GOid=GO:0033458; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20150206"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033458; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNAASP.01"
FT   tRNA            14314..14385
FT                   /gene="SPMITTRNAGLY.01"
FT                   /product="tRNA Glycine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033463;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=GGA codon-amino acid adaptor activity;
FT                   GOid=GO:0033463; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20150206"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033463; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNAGLY.01"
FT   tRNA            14394..14476
FT                   /gene="SPMITTRNALEU.01"
FT                   /product="tRNA Leucine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033403;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=UUA codon-amino acid adaptor activity;
FT                   GOid=GO:0033403; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20150206"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033403; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNALEU.01"
FT   tRNA            14492..14563
FT                   /gene="SPMITTRNATRP.01"
FT                   /product="tRNA Tryptophan, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033416;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=UGG codon-amino acid adaptor activity;
FT                   GOid=GO:0033416; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20070713"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033416; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNATRP.01"
FT   tRNA            14596..14669
FT                   /gene="SPMITTRNALEU.02"
FT                   /product="tRNA Leucine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033419;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=CUA codon-amino acid adaptor activity;
FT                   GOid=GO:0033419; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20070713"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033419; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNALEU.02"
FT   CDS             14756..15529
FT                   /transl_table=4
FT                   /gene="atp6"
FT                   /primary_name="atp6"
FT                   /systematic_id="SPMIT.07"
FT                   /product="F1-FO ATP synthase subunit 6 (predicted)"
FT                   /colour=7
FT                   /GO="aspect=C; term=proton-transporting ATP synthase
FT                   complex, coupling factor F(o) (sensu Eukaryota);
FT                   GOid=GO:0000276; evidence=ISS; db_xref=GO_REF:0000024;
FT                   with=SGD:S000007268; date=20040810"
FT                   /GO="aspect=F; term=hydrogen-transporting ATP synthase
FT                   activity, rotational mechanism; qualifier=contributes_to;
FT                   GOid=GO:0046933; evidence=ISS; db_xref=GO_REF:0000024;
FT                   with=SGD:S000007268; date=20040810"
FT                   /GO="aspect=F; term=structural molecule activity;
FT                   GOid=GO:0005198; evidence=ISS; db_xref=GO_REF:0000024;
FT                   with=SGD:S000007268; date=20051007"
FT                   /GO="aspect=P; term=ATP synthesis coupled proton transport
FT                   (sensu Eukaryota); GOid=GO:0042776; evidence=ISS;
FT                   db_xref=GO_REF:0000024; with=SGD:S000007268;
FT                   date=20040810"
FT                   /fasta_file="fasta/pMIT.tab.seq.00054.out"
FT                   /controlled_curation="term=orthologous to S. cerevisiae
FT                   Q0085; date=20070911"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in bacteria; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in fungi; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in eukaryotes; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in metazoa; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in vertebrates; date=20100820"
FT                   /controlled_curation="term=species distribution,
FT                   predominantly single copy (one to one); date=20100820"
FT                   /controlled_curation="term=disease associated,
FT                   neurological disorders; db_xref=PMID:18461509;
FT                   date=20141024"
FT                   /controlled_curation="term=disease associated, Leigh
FT                   syndrome; db_xref=PMID:18461509; date=20141024"
FT                   /controlled_curation="term=disease associated,
FT                   mitochondrial disorders; date=20150428"
FT                   /controlled_curation="term=disease associated, NARP;
FT                   date=20150428"
FT   tRNA            15550..15622
FT                   /gene="SPMITTRNAHIS.01"
FT                   /product="tRNA Histidine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033426;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=CAC codon-amino acid adaptor activity;
FT                   GOid=GO:0033426; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20070713"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033426; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNAHIS.01"
FT   tRNA            15661..15735
FT                   /gene="SPMITTRNAPRO.01"
FT                   /product="tRNA Proline, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033423;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033423; db_xref=GO_REF:0000050;
FT                   date=20070713"
FT                   /GO="aspect=F; term=CCA codon-amino acid adaptor activity;
FT                   GOid=GO:0033423; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20150206"
FT                   /systematic_id="SPMITTRNAPRO.01"
FT   tRNA            15747..15819
FT                   /gene="SPMITTRNAGLN.01"
FT                   /product="tRNA Glutamine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033427;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=CAA codon-amino acid adaptor activity;
FT                   GOid=GO:0033427; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20150206"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033427; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNAGLN.01"
FT   CDS             15954..16637
FT                   /transl_table=4
FT                   /systematic_id="SPMIT.08"
FT                   /product="mitochondrial ribosomal small subunit Var1"
FT                   /colour=7
FT                   /fasta_file="fasta/pMIT.tab.seq.00059.out"
FT                   /GO="aspect=C; term=mitochondrial small ribosomal subunit;
FT                   GOid=GO:0005763; evidence=ISS; db_xref=GO_REF:0000024;
FT                   with=SGD:S000007275; date=20041012"
FT                   /GO="aspect=P; term=mitochondrial translation;
FT                   GOid=GO:0032543; evidence=ISS; db_xref=GO_REF:0000024;
FT                   with=SGD:S000007275; date=20041012"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in fungi; date=20070727"
FT                   /controlled_curation="term=orthologous to S. cerevisiae
FT                   Q0140; date=20070727"
FT                   /primary_name="var1"
FT                   /synonym="urfa"
FT   tRNA            16662..16734
FT                   /gene="SPMITTRNAILE.01"
FT                   /product="tRNA Isoleucine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033434;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=AUC codon-amino acid adaptor activity;
FT                   GOid=GO:0033434; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20070713"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033434; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNAILE.01"
FT   CDS             16914..17060
FT                   /transl_table=4
FT                   /product="F1-FO ATP synthase subunit 8 (predicted)"
FT                   /gene="atp8"
FT                   /primary_name="atp8"
FT                   /systematic_id="SPMIT.09"
FT                   /colour=7
FT                   /GO="aspect=C; term=proton-transporting ATP synthase
FT                   complex, coupling factor F(o) (sensu Eukaryota);
FT                   GOid=GO:0000276; evidence=ISS; db_xref=GO_REF:0000024;
FT                   with=SGD:S000007267; date=20040810"
FT                   /GO="aspect=F; term=hydrogen-transporting ATP synthase
FT                   activity, rotational mechanism; qualifier=contributes_to;
FT                   GOid=GO:0046933; evidence=ISS; db_xref=GO_REF:0000024;
FT                   with=SGD:S000007267; date=20040810"
FT                   /GO="aspect=P; term=ATP synthesis coupled proton transport
FT                   (sensu Eukaryota); GOid=GO:0042776; evidence=ISS;
FT                   db_xref=GO_REF:0000024; with=SGD:S000007267;
FT                   date=20040810"
FT                   /fasta_file="fasta/pMIT.tab.seq.00056.out"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in fungi; date=20070212"
FT                   /controlled_curation="term=orthologous to S. cerevisiae
FT                   Q0080; date=20071118"
FT                   /controlled_curation="term=disease associated,
FT                   neurological disorders; date=20180429"
FT                   /controlled_curation="term=disease associated,
FT                   mitochondrial disorders; date=20180429"
FT                   /controlled_curation="term=human MT-ATP8 ortholog;
FT                   date=20180822"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in vertebrates;  date=20180822"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in eukaryotes;  date=20180822"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in metazoa;  date=20180822"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in eukaryotes only;  date=20180822"
FT   tRNA            17082..17150
FT                   /gene="SPMITTRNACYS.01"
FT                   /product="tRNA Cysteine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033414;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=UGC codon-amino acid adaptor activity;
FT                   GOid=GO:0033414; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20070713"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033414; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNACYS.01"
FT   tRNA            17166..17238
FT                   /gene="SPMITTRNAVAL.01"
FT                   /product="tRNA Valine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033451;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=GUA codon-amino acid adaptor activity;
FT                   GOid=GO:0033451; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20150206"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033451; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNAVAL.01"
FT   tRNA            17257..17342
FT                   /gene="SPMITTRNATYR.01"
FT                   /product="tRNA Tyrosine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033410;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=UAC codon-amino acid adaptor activity;
FT                   GOid=GO:0033410; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20150206"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033410; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNATYR.01"
FT   tRNA            17460..17532
FT                   /gene="SPMITTRNAARG.02"
FT                   /product="tRNA Arginine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033431;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=CGA codon-amino acid adaptor activity;
FT                   GOid=GO:0033431; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20070713"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033431; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNAARG.02"
FT   tRNA            17542..17613
FT                   /gene="SPMITTRNAILE.02"
FT                   /product="tRNA Isoleucine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033434;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=AUC codon-amino acid adaptor activity;
FT                   GOid=GO:0033434; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20070713"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033434; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNAILE.02"
FT   tRNA            17635..17716
FT                   /gene="SPMITTRNASER.02"
FT                   /product="tRNA Serine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033407;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=UCA codon-amino acid adaptor activity;
FT                   GOid=GO:0033407; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20150206"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033407; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNASER.02"
FT   CDS             17806..18030
FT                   /EC_number="3.6.3.14"
FT                   /transl_table=4
FT                   /gene="atp9"
FT                   /primary_name="atp9"
FT                   /systematic_id="SPMIT.10"
FT                   /product="F1-FO ATP synthase subunit 9 (predicted)"
FT                   /colour=7
FT                   /GO="aspect=C; term=proton-transporting ATP synthase
FT                   complex, coupling factor F(o) (sensu Eukaryota);
FT                   GOid=GO:0000276; evidence=ISS; db_xref=GO_REF:0000024;
FT                   with=SGD:S000007274; date=20040810"
FT                   /GO="aspect=F; term=hydrogen-transporting ATP synthase
FT                   activity, rotational mechanism; qualifier=contributes_to;
FT                   GOid=GO:0046933; evidence=ISS; db_xref=GO_REF:0000024;
FT                   with=SGD:S000007274; date=20040810"
FT                   /GO="aspect=P; term=ATP synthesis coupled proton transport
FT                   (sensu Eukaryota); GOid=GO:0042776; evidence=ISS;
FT                   db_xref=GO_REF:0000024; with=SGD:S000007274;
FT                   date=20040810"
FT                   /fasta_file="fasta/pMIT.tab.seq.00057.out"
FT                   /controlled_curation="term=orthologous to S. cerevisiae
FT                   Q0130; date=20080204"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in bacteria; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in fungi; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in eukaryotes; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in metazoa; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in vertebrates; date=20100820"
FT   tRNA            18057..18129
FT                   /gene="SPMITTRNAALA.01"
FT                   /product="tRNA Alanine, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033455;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=GCA codon-amino acid adaptor activity;
FT                   GOid=GO:0033455; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20070713"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033455; db_xref=GO_REF:0000111;
FT                   date=20150206"
FT                   /systematic_id="SPMITTRNAALA.01"
FT   ncRNA           18130..18403
FT                   /primary_name="rnpB"
FT                   /systematic_id="SPMITNCRNA.01"
FT                   /product="mitochondrial RNase P RNA"
FT                   /GO="aspect=P; term=mitochondrial tRNA processing;
FT                   GOid=GO:0090646; evidence=TAS; db_xref=PMID:29954949;
FT                   date=20180809"
FT                   /GO="aspect=C; term=mitochondrial ribonuclease P complex;
FT                   GOid=GO:0030678; evidence=TAS; db_xref=PMID:29954949;
FT                   date=20180809"
FT                   /GO="aspect=F; term=ribonuclease P activity;
FT                   qualifier=contributes_to; GOid=GO:0004526; evidence=TAS;
FT                   db_xref=PMID:29954949; date=20180809"
FT                   /controlled_curation="term=warning, new gene;
FT                   db_xref=PMID:29954949; date=20180809"
FT                   /db_xref="PMID:29954949"
FT   tRNA            18404..18475
FT                   /gene="SPMITTRNAGLU.01"
FT                   /product="tRNA Glutamic acid, mitochondrial"
FT                   /GO="aspect=P; term=mitochondrial translational
FT                   elongation; GOid=GO:0070125; evidence=IC; from=GO:0033459;
FT                   db_xref=GO_REF:0000111; date=20070713"
FT                   /GO="aspect=F; term=GAA codon-amino acid adaptor activity;
FT                   GOid=GO:0033459; evidence=ISM; db_xref=GO_REF:0000050;
FT                   date=20150206"
FT                   /GO="aspect=C; term=mitochondrion; GOid=GO:0005739;
FT                   evidence=IC; from=GO:0033459; db_xref=GO_REF:0000111;
FT                   date=20070713"
FT                   /systematic_id="SPMITTRNAGLU.01"
FT   CDS             18561..19307
FT                   /transl_table=4
FT                   /gene="cox2"
FT                   /primary_name="cox2"
FT                   /systematic_id="SPMIT.11"
FT                   /product="cytochrome c oxidase 2"
FT                   /colour=2
FT                   /GO="aspect=C; term=respiratory chain complex IV (sensu
FT                   Eukaryota); GOid=GO:0005751; evidence=ISS;
FT                   db_xref=GO_REF:0000024; with=SGD:S000007281;
FT                   date=20040629"
FT                   /controlled_curation="term=orthologous to S. cerevisiae
FT                   Q0250; date=20070911"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in bacteria; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in fungi; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in eukaryotes; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in metazoa; date=20100820"
FT                   /controlled_curation="term=species distribution, conserved
FT                   in vertebrates; date=20100820"
FT                   /controlled_curation="term=species distribution,
FT                   predominantly single copy (one to one); date=20100820"
SQ   Sequence 19431 BP; 6562 A; 2783 C; 3064 G; 7022 T; 0 other;SQ   Sequence 19431 BP; 6562 A; 2783 C; 3064 G; 7022 T; 0 other;SQ   Sequence 19431 BP; 6562 A; 2783 C; 3064 G; 7022 T; 0 other;SQ   Sequence 19431 BP; 6562 A; 2783 C; 3064 G; 7022 T; 0 other;
     aatgtgtaat ttgaatcaat ttctatcctt ttaaaaatac atcataaagt gtactttttt        60
     aaggatttag ttattaaagg attaattatg gattgctaac cagttaatat taagaggaag       120
     cttttaaagc ttaattcagc aattttttaa ttgttgtttc tcctaaaggt aaaccactaa       180
     aaagaaagaa cttcgggttt ttctttaaaa taaactagag gaactgaatc atcttagtac       240
     tctaaggaaa ataaaataac aatgattatt gtagtagtgg cgaacgaatc attaatagtc       300
     taacttataa aaatattaaa aaaaattttt accaaagaag agaaaaatgg gttcttcatt       360
     tttaataagt aataagtaat aaagtaaaat gggaacttaa cctgtttgaa tattggagaa       420
     ccaatctcca aagactaaat atattaactg agtgatagtg aagagtaccg taagggaaag       480
     caatgaaata gttaatctat aagcgaagat agtgaatttt aaataaatta ttatcttgta       540
     ccttttgcat aatgggtcag caagttttaa ttatttgcaa gctgaaaagc cataaagtaa       600
     ataattaaag acccgaaacc tgacgatctt accatgaaca gattttaagg atcgaaccag       660
     taatcgttgc aaagattttg gatgatttgt ggtaaggggt gaaatgctaa tcgagttagg       720
     tgatagctgg ttgtccacga aaccatttta agatgggcac ttcaaaaact aaatgaggta       780
     cagaaattta ttgccttcaa gaagtttttt cttgttaata ggggatctaa agatttacct       840
     aaggcgttaa ttaatctcgg aataaattta aaaaagtttg aagtagttag acaattggcg       900
     ataaggtcaa tagtcaaaag agaaacagct cagatcaaag atttaaagtt ccccaattta       960
     agttaagtga tttaaagata gtcttactcc ttattcaata agaatatggg cttggaaaca      1020
     gccattatct aaggagtacg taatagttca cttatccaaa aaaaataata ttttctggag      1080
     aaaggcatca aaaatttaac ggatcttaaa cttaatactt aaactttggc agtattttaa      1140
     aaatactggg tagtggaccg atctatataa agatgaagat gaacttttaa gtttattgga      1200
     tttattagat gcgagaatgc tgacataagt aacgtaaaaa aaggtcaaat tccttttcac      1260
     cgaaaactga agggttttga cttaaaaagc ttagcttaag tcaaataaag taacaatctc      1320
     taagctaata aatagtgatg agtaaatctt aacggatctt aaaataaaag ttttattgaa      1380
     tagaaatttt tattcaggaa aattatccgt tattttaatt gtaccctaaa ccgacactgg      1440
     tcagttaaga gaatatctta aggtgttgag agaactatgc ttaaggaact cggcaaatta      1500
     gctctgttac ttcggtataa agagtgttca ttattttatg aactcaataa agagaaccct      1560
     acaactgttt acttaaaaca cagcacattg ccaaaattaa aaaattatag tataatgtgt      1620
     gaggtctgct caatgtccta tggttaacaa tacgaacttt aacgagtttt acggaaccca      1680
     ggataaatag cggctttaac tctgagggtc ctaaggtagc gaaattcctt gtccgataaa      1740
     tacggtcccg catgaatgac ttaatgatag ggttgctgtc tcaagcacag actcagtgaa      1800
     attgtaattg ctgtgaagat acagtgttcc ctcagctaga cggaaagacc ctggcagctt      1860
     tacgatagtt aattattgat taaagaaaaa atcatccaaa aggtgatctc ttctttctcg      1920
     ctttatctat ttttgttcag tatagaggtt agtcgtttag acaaaaatga gatatcctcc      1980
     ttaaataata aagatcttta aagtttaaac ttgacattaa ttaattgatc gtttctgtgg      2040
     ggcgcaggcc tcataaaaaa taactgaggt atcctagatc tatataattt atctagaaat      2100
     caaagtatcc agaaacattt tttaagtgtt tcttaattaa agatacatga cgcatataag      2160
     cataaatagg ttaaactgaa agactaacaa gtcgcacaga tatgtaaata gggttaaatg      2220
     atccacattg aaacactaat ttagtgtttg tatggaaaac aatgtgctca atgagcgaag      2280
     ttacgccagg gataacaggt taatagagag ctaaagtaca aatcaaattc tctgtttgac      2340
     acctcgatgt cgactcaacc tatctccggt tgtagcagat tggaagggtt agactgttcg      2400
     tctatttaaa aggttacgtg agttgggtta aatccgtcgt aagacaggat ggttcctatc      2460
     tactgaggga aaaataagca aattaaaatt tatcttttgt acgcaaggat ttagataatt      2520
     caatctctag tttaactatt gttacttaaa taaaagtact ttattcaaaa gttaaaaatt      2580
     aagtagcacg gtagtaaagc caaattgaac aaattaaaaa ctgaaagcat ctcaagtttg      2640
     aaatttattt aaagagctta tattaagaaa gtagaaaact ttccaaaagg acatccttag      2700
     gatgtacaaa tccttatttt agtaaatcat tgtttagata gatttagtta attttttaac      2760
     caaagggatt atctctttgc taatttttta aataactgga aattgcctaa ttacacaatt      2820
     ttttttacca tttttttgat gagggtattg tttaaagggg atgtagctca atggttagag      2880
     ctttcgcctt ttaagcgata ggataagggt tcaaatccct tcagacccat aaataaaaga      2940
     actaacttct cataaaagtg agttaaagga aaaatagttc taattggtaa gaaggatact      3000
     tgctacgtat ctggtgaata accttgtgag ttcgagtctc actttttccg taaatatttg      3060
     ttgttgtagc tcaatggtag agcaagtcac tgttaatgac ctgatagtgg ttcgattcca      3120
     ctcaataacg ataaaaatat atataatgag tttgatgtta gctcggttat aacgctatct      3180
     agagatttta acacatgcaa atcgaacgaa tcaacaaaaa caatacatcc tttaggggat      3240
     gtttgtgttt ttttgtgacg tggtgaacag gtgagtaaaa gggaagaacg gaccttaaat      3300
     ttcggctaaa ttccgaataa acacactctt ttggagtgtt gtgaaagaag tgaaaacttt      3360
     gatttaagac tggcttctta cgattaaagt agttggagag gtaaaagctt aacaagctca      3420
     aatcgtaatc atgacactaa gtggtgctct gatcacattg gctctgagac aacagccaag      3480
     atgaacattt agttcatcca gcagtggaga atattagtca atgatcgaaa gattgaacta      3540
     gtcatctaga agagtgaaac ttttagttat agctccttaa attaagaaaa tttgattctt      3600
     aattttatgt aattcttgcc aatttccgtg ccagcagcag cggttatacg gatagaataa      3660
     gcgtttaaca taataaaaag gcctaaaaag tatgtagatg gaaaaaaaca aatctttttc      3720
     tagagtaata aagatgtttg tagtattgtc aaataaggga tcaaatccga caatcttgat      3780
     gagactgctt aagtaaaaac tacttacaat taattactga cattgagata cgaaggctta      3840
     gatcgcgaaa gagattagat acctctgtag tctaagctgt aaacgattat tgctctccca      3900
     atctttttga ttgggtttag tgaagacggt aagcaatatg cctggggagt actttcgcaa      3960
     gattgaaacc caaaacatta gacggtcttg gaaatccgca gtgaatcatg ttatttaatt      4020
     agataatccg ctaaaaatct tacctttcct taaaacaatt agttttaatt gttgggtatt      4080
     gcatggctgt ctttagttaa tctcgtaaga tgaggttaat tcccattaat taacgaaagc      4140
     cttcaaagaa tttgtttttc tttgtgttag tgataagcta actttttaga gggttaagac      4200
     aagtcaatat gatccttatg gaaagggcta tagacgtgat ataaaatcta atccaataat      4260
     ttttaatatc gaaagattga agtattatta taatggttag gagatttatt cagatttaaa      4320
     tctgtaattt gatttaatga aggaggaatt gcgagtaatc actaatcatt acgtagtggt      4380
     gaaatttatc tctgagatgt actaactact cgtcaagcgc tgaaagtatt aatctcttga      4440
     agaagacatt catttgtttt cccaaggtgt tgtgcaatta gtgttaagtc gaaataaggt      4500
     aaccgtagtg gaagttgcgg ttgaactaat taattcaggt taaccccccc ccaaaaaata      4560
     aaatacatcc atatcaaaaa gatgttaatt gttggtatag tttaattggt taaaataatc      4620
     tcctcatgtg agattgatct ataggttcga gcccttttac caacttttcc ttaaccacat      4680
     ctgtttaagt caaaaaatct taaatggtag gaaaccttta aacaaagttt aaaaaagtta      4740
     ttaaataatc ttaatgatct tttcatctac cctaaaaata ttgaatcctt ttaaaatagt      4800
     ttaataaatt agcttttgga tgaaaactaa aaattttttt ttaacttaaa cttatttaga      4860
     aattaataat ttagtcttga gtttaatgaa ctcttggtgg acttatgtta atagatggat      4920
     attctcaact aatgctaagg atattgccat actatattta ttattcggat tggtatctgg      4980
     gataattgga tctgtattct cttttataat tagaatggaa ctatcagctc caggatctca      5040
     attcctttct ggaaatggtc aattatacaa tgttgcaatc tcagcacatg gtatacttat      5100
     gatttttttc ttcattattc ctgctttatt tggtgcattt ggtaattatt tagtacctct      5160
     tatgataggt gctccagatg ttgcttaccc tagagtaaat aatttcacat tctggttact      5220
     acctcctgct ctaatgctat tattaatttc tgcattaaca gaagaaggac ctggtggtgg      5280
     ttggacggtt ttaaagccgc agacaaaatt gtctgaaaac tcttctcgat gcgaaaaagt      5340
     cctctactcg gaagtaatta ctcagttaat ttatttttta actagtaaaa agattactaa      5400
     cttggggaaa attcgcctgg ttaaatccat cagagactcg tttctatcac aattagaaaa      5460
     tattttatgt ttctttttgg tttatagaac aacatactct ttcggagtgt gtttaatgaa      5520
     gaggttctta tttaataaat tttttaatag acatcctttt acaagggtaa aaagctgttt      5580
     ttcatcatct tcaccatcaa aattctcttt tactcaatgg ttagtaggat ttactgatgg      5640
     tgatggttgt tttagtattt caaaacaaaa aataaaaaat ggcaaaaata aatggtctct      5700
     tacttttaaa ttaacacaaa atctttataa ttatagaatt ttatatttta ttaagagaaa      5760
     tttaggtatt ggttcacttt ataaagaatc ttcaactaat acagtaatat atagattaag      5820
     aagaagagag catcttaaaa agattataga tatttttgat caattccctc ttttaactaa      5880
     aaaatattgg gattattatt tgtttaaaaa agcattctta attttagagg acgctaatct      5940
     aaattctttt gaaaaaaata gtaaactaga agagatcaga atagagaaaa agtctttaaa      6000
     acaatattct ccagttaatt tagaaaaata tttaacaaag tcttggttaa ttggatttat      6060
     tgaagcagaa gggagctttt atttactaca aaaaagccct gtaagaataa ttcatgggtt      6120
     tgagattact caaaattatg aacaacccct acttgctcag atttcagagt tcctatttaa      6180
     ttctcaaatc tcaccaaaaa taaaatcaaa aaaaaattcc ttaattacaa attattcctt      6240
     atcaactagt tcaaaagaaa gaatgttatt tctttcatct tattttgaaa attgttttaa      6300
     aggagtaaaa tcattagaat ttaaaatttg gtctagatct ttacgtaaaa attataattt      6360
     tgaacagctt ttaagagcta gagatttaat tagaaaatta aaaaataaat attcccgagg      6420
     atcacaacat ccaaaggata aataaaataa gttcaaggta tagtccgatc aagattgaga      6480
     aatcttgtta actaaaatga tatccaccac tatcaagtat cacttctcat agtggtccag      6540
     ctattgatct agctatttta agtttacaat taactggtat ttcatcaaca ttaggatcag      6600
     taaatttaat agcgacaatg attaatatga gagctccagg attaagttta tatcaaatgc      6660
     cattatttgc atgggctata atgattacat caattctatt actgcttact ttaccagttt      6720
     tagcaggtgg attatttatg ttattctcag atagaaattt aaatacttca ttctatgctc      6780
     ctgaaggtgg tggtgaccct gtactttacc aacatttatt ctggttcttt ggtcatccag      6840
     aggtcaattt aataggcctc ttaacgttgc tatatgctgg aactacttga aaaatactag      6900
     ataagagttt ttgttttaaa tactccaaga aaaacaccag attagtgttt atttttatag      6960
     taaaaatgtt aaaacaatta agtatatcag caggtaacct tttgaataag ggaacctcag      7020
     agactttacg caacgaaatc acaacaaaaa aagtttctat tcatctccct aaacacttaa      7080
     aaccagctaa tgattctcaa tttggtcact atttagcagg tttaattgat ggtgatggtc      7140
     attttagtag taaacaacaa ttaattattg cttttcactc tttagatata caattagctt      7200
     attatattaa aaaacaaata ggttatggta ttgtacgtaa aattaaagat aaaaatgcta      7260
     ttctttttat aatagctaac tctaaaggaa ttgaaagagt aataacttta attaataata      7320
     aatttagaac tactagtaaa tataatcaga ttattaataa tatatttgct catcctagat      7380
     ttaaagaatt tagtaaaact attactttag gtttaaattc aaataataat ttaaataatc      7440
     attggctagc tggattctca gatgctgatg ctagttttca gattaaaatt ttaaataggg      7500
     acaaaaaaat agaagttcga ttgaactatc aaatagatca aaaaaaagag tatcttttga      7560
     gtttaattaa agataattta ggtggtaata taggctatcg aaaaagtcaa gatacttatt      7620
     attatggttc tactagtttt ggttcagcta aaaaagttat taattatttt gataattatc      7680
     atttgctatc ttctaaatat attagctatt taaaatgaag aaaagcttat cttattattc      7740
     aagaaaataa acatttaaca gaatcaggac tttctcaaat aaaaaaacct catccctatc      7800
     ggaagaatat taattagatt tgttgagatt taaaataaag tcctaacaag ggtataaagc      7860
     ttttgagtgt taaaaagaat aaatcacctt ttgggtgatt ttttttcatt aaccaaaatt      7920
     tattgttata ttttaattat gccagctttc ggtgttgtta gtcacattat tcctagttta      7980
     gctcataaac ctattttcgg taaagaaggt atgctttggg ctatgttaag tattgcttta      8040
     ttaggattaa tggtatggtc tcatcactta ttcacagttg gtttagatgt tgatactaga      8100
     gcttatttca gtgctgcaac tatggttatt gcaattccaa caggtattaa aatcttcagt      8160
     tggttagcta ctttaacagg tggtgcaata caatggtcaa gagtacctat gttatatgct      8220
     attggtttct taatcttatt cacaattggt ggattaacag gtgttatatt aagtaattca      8280
     gtattagata tcgctttcca tgatacttat ttcgttgtag ctcacttcca ttacgttctg      8340
     tcaatgggtg cattatttgg tctttgtggt gcatactatt ggagtccaaa aatgtttgga      8400
     ttaatgtaca atgaaactct agcttcaatc caattctgga ttttattcat aggtgttaat      8460
     attgtattcg gtcctcaaca tttcttagga ttaaatggta tgcctagaag aataccagat      8520
     tatccagagg catttgtggg atggaatttt gtatcaagta ttggttcagt aatttctatt      8580
     ctttcattat tcctatttat gtatgttatg tatgatcaat ttacatcaaa tagagtggtt      8640
     aaaacaaatc cttatttaat ccctagctat tttgatgata atgtaatctt cgtaaatgaa      8700
     aaattagggg tagctcaatc aatagaatgg ttactacatt caccagtaca cgaacacgca      8760
     tttaatacat tacctacaaa aagtatttaa tttaaaatct taacccccct tttattttat      8820
     aaactttatt ccaatttaaa aattggagag ggagattgaa ggataattta gctatcctat      8880
     tcaaaattgt atctttataa tttttttatt ccttatatgt gagagaacac tattgagata      8940
     aactaattta gcttaaacat gaatctttct actaaatttc aaggacatcc ttatcatatt      9000
     gtaagtgcgt caccttggcc atttttctta tctgtagtat tattctttaa ctgtttagca      9060
     gctacattat atttacatgg atacaaacat tcatcagtat tctttggaat cagtttctta      9120
     ggtttattag caactatgta tttatggttt agagatatgt caactgaagc taatattcat      9180
     ggtgcacata caaaagcagt aacaaaagga ttaaaaatag gatttatgtt attcctaatt      9240
     tctgaaactt tcttatttgc ttctattttc tgggctttct tccatagttc attatcacct      9300
     acttttgaat taggtgcagt atggccacca gtaggaatag cagataaaac aatagatcca      9360
     ttagaagtcc ctctattaaa tacagtaatt ttattaactt ctggtgctag tttaacttat      9420
     gctcattatt cattaattgc tagaaataga gaaaatgctt taaaaggttt atatatgact      9480
     atcgctttat cattcttatt cttaggaggt caagcttatg aatactggaa tgctccattc      9540
     actatttcag attctgttta tggtgctagt ttctattttg ctactggtct tcatggtatt      9600
     catattattg ttggtacaat tctacttctt gttgctactt ataatattta tacttaccac      9660
     ttaactaata ctcatcataa tggatttgaa tgtggtattt attattggca tttctgtgat      9720
     gttgtttggt tattccttta tttaactatt tatatttggg gtagctaagg cttacttcaa      9780
     tttttccccc ctttttatat cttatttctc taaaatagtc tgtatagctc aatggtagag      9840
     catctcactt ctaatgagtc gatctaagtt cgattcttag tacagattcc acacctagaa      9900
     ggtgtgtatt ttttttttag ctaatttaac tcaattggta gagtgcgtac cttgtaagta      9960
     cgaagttaga ggttcaattc ctctaattag caatcccttt cccatatttt tggtataaga     10020
     ggatctcaga tagtatctaa cctatcttat cttttattat ccaatatcct tttaataaga     10080
     tttggatctt ttttcccaat tccttcaaat ttttgactat ttatcgataa tgattgttca     10140
     atttagaagg gataatttca aatttaattt ttatgaaaat tttaaaatct aatccttttt     10200
     tagctttggc taataattat atgattgatg ctcctgaacc ttcaaatatt tcatacttct     10260
     ggaattttgg ttctctttta gcttgtgtat tagttattca aattgtaatc ggtatacttt     10320
     tagcttgttt ttatattcct aatatggatt tagctttcct ttcagttgaa agaattgtta     10380
     gagatgtaaa ttatggtttc ttattaagag ctttccatgc aaatggtgct agtttcttct     10440
     ttatcttctt atacttacac ataggtagag gtttatatta tggttcttat aaatatccaa     10500
     gaacaatgac atggaatatt ggtgttatta tcttcttatt aactattatt actgcctttt     10560
     taggttactg tttaccagct aatcaaatgt cattctgggg tgcaactgtt attactaatt     10620
     tattatcagc tgttcctttc attggtgatg atttagttca tctattatgg ggtggattta     10680
     gtgtatctaa tcctacttta aatagattct tctcacttca ctatttaatg ccttttgtta     10740
     ttgctgcttt atcagtaatg catttaattg ctctacatac taatggttca tcaaatccat     10800
     taggtgtaac agctaatatg gacagaatcc caatgaaccc gtattatctg ataaaattgc     10860
     gccgttgtgg tatatatgtg taccctcata gagaaaggga tatcttgtgt gtaaagatat     10920
     gaacaataca cttaggtagc tggggaaacc caatgccgaa cagagcatgt gtacagaagg     10980
     tccttcctgt aacgaaacag ataagttcag atggatcagt tcaaatagat acggttagag     11040
     ctgtattgcc cgaattccaa ttcccatctc accctcagat aggtgattgt cttagctgaa     11100
     tagagacatt cttctctaga tctttggttg gcttttatga ccaaggatac acaccaggag     11160
     aagagagttg taccaatagt acaattaagg gaatgagtgg aaaacctacg tctatcatct     11220
     caaacatata tacaactacg ggtcccgcta aggtcagtaa tgactatgcg gtcagagatc     11280
     ctggagtagc tgttgatcat tttgatcaat acggtccttt gaaagaggga agaagtttga     11340
     actctgcaaa gatttcaaca cagtgaagtg gatcagctac attaaagtct tccaatagat     11400
     caatatttaa tattggttta ggatacatta atactttttt aggggtatct aatgtaagag     11460
     gatttagtac aggatcagga cgatcaaaaa atgtactaaa taaactagac gatttatcta     11520
     aacgatcaaa aaattatcct aatcttgtaa ttgatagaaa tctctacaaa gatttcctat     11580
     taaatcgaga tatgttcctt attgcttata ataaattaaa atctaatcct ggtatgatga     11640
     ctcatggtct taaaccggat actttagatg gaatgtctat agatgttatt gataaaatta     11700
     tccaaagcct taaatctgaa gaatttaact tcactcctgg tagacgtatc ttaattgata     11760
     aagccagtgg tggaaaaaga ccattaacaa ttggtagtcc tcgagacaaa ttagttcaag     11820
     aaattcttag aatagtcctt gaggctatct atgaaccatt atttaatact gcttctcatg     11880
     gatttagacc aggtcgaagt tgtcattctg ctcttagatc tattttcact aattttaaag     11940
     gttgtacttg gtggattgaa ggagatatta aagcttgttt tgattctatc cctcatgata     12000
     aattaattgc tctattatct tctaaaatta aagatcaacg atttattcaa ttaattcgta     12060
     aagctttaaa tgctggatat ctaactgaaa atagatataa atacgatatt gttggaactc     12120
     ctcaaggttc tatagttagt cctatcttag caaatatcta ccttcatcaa ttggatgaat     12180
     ttattgaaaa cctaaaatca gaatttgatt acaaaggtcc aatagctcgt aaaagaactt     12240
     ctgaatctag acatcttcat tatctaatgg caaaagccaa aagagaaaat gctgattcaa     12300
     aaacaattag aaaaatagcg attgaaatgc gtaatgttcc taataagata catggtattc     12360
     aatctaataa actaatgtat gttcgatacg ctgatgattg gatagttgca gttaatggaa     12420
     gttatactca aactaaagag attttagcta aaattacctg tttctgttca tcaattggac     12480
     taacagtatc tccaactaag actaaaataa ctaattcata tacggataaa atacttttcc     12540
     ttggtactaa tattagccat tctaaaaatg ttacctttag tagacatttt ggtatacttc     12600
     aaagaaattc tgggtttatt ttactttctg ctcctatgga tcgaattgca aaaaaactta     12660
     gagaaactgg acttatgctt aatcataaag gtagatctgt tattagatgg ttacctcttg     12720
     atgtacgaca aattattggt ttagcgaatt ctattattag aggttacgat aattattatt     12780
     cttttgttca taatagagga agatttgcta cttacgttta cttcataatt aaagactgtg     12840
     ttcttcgaac attagctcat aaattatcat taggtactag aatgaaagta attaaaaaat     12900
     ttggtcctga cctttctatc tatgattaca actctagaga tgaaaataat aaaccaaaat     12960
     taattaccca attatttaaa ccttcttgga aagttaatgt ttggggattt aaatctgaca     13020
     aagttaaatt gaacattaga acactttatg cttctcactt atcaatggct aacttagaaa     13080
     atctacagtg tgctgcttgt caaagtactt ataaagtgga aatgcatcat gttagacaga     13140
     tgaaaaatct taaaccaatc aaaggtactt tagattactt aatggcaaaa gcaaacagaa     13200
     aacaaattcc attatgtaga tcttgtcaca tgaaacttca tgctaataag ttaactctta     13260
     atgaggataa aaaagtttag atatcttaaa tgtagtggag agccgtataa ttacgaaagt     13320
     atcccgtacg gttcggtgac gagccgtgtc aaccctgcaa agggaatgcg tcttagttca     13380
     atgatttgat aacaatattt atcttcttaa tcggtataaa ttatatggca ttctataatc     13440
     catatggatt tatggaacca gattgtgctt taccagcgga tcctctaaaa actccaatgt     13500
     ctattgttcc agaatggtat ttattacctt tctatgctat tttaagagct atacctaact     13560
     tccaattagg agttatagca atgttattat caatcttagt attactatta ttaccattat     13620
     tagatttctc agctattaga ggtaatagtt ttaacccatt tggtaaattc ttcttctgga     13680
     catttgttgc cgattttgta attcttgcat ggattggtgg atcacatcca gaaaacgtct     13740
     ttatcacaat cggtgctatt gctacaatct tctattttag ctacttcttt attttaatac     13800
     cagtatatac tatattaggt aatacattaa ttgatttaaa tttaagctca attaaacgat     13860
     aatctcttcc ccctttacac tatataaaaa tatcttattt aaacagtata atatttaata     13920
     aaaagctcat caaaaggtat gaataaaagt tttttacata gattaggtaa taaaacattc     13980
     tttgggtgtt agtagtgatt agaagaagtt gatcttttag ggatttattt ttatcagaat     14040
     ttttacggtc aatttttatc taattaaatg tgaataagtt tgcgatttaa tgtaattggt     14100
     taacatctct gactcatgat cagtgtatta aggttcaagt ccttaggtcg cactttatgc     14160
     tctgataact taacggttaa agtgcagtat tgaagctgct gagatattgg ttcgattcca     14220
     tttcagagca aataaaagaa tctgtagctt aaagtaaagt atcgccttgt cacggtgatg     14280
     gatgcccact cgtactgggt cagattcgtt taagcagata taagtcaatt ggcagacctt     14340
     ctgatttcca cttagattat gttcgttcga atcggactat ctgcattaaa taagcctaaa     14400
     tgctggaatt tggtagacag aacaaactta agatttgtcg ctttcgagcg tgttggttcg     14460
     agtccaactt taggtataac taaaaaaaaa aaagagtata gtttaattgg taaaacttct     14520
     gattccaaat tagacattgt tcgttcaagt cggactgctc ttgatttttt attctttgat     14580
     ctgttaggga agtatgcaga tgtgatgaaa ttggtaaaca tgtttacctt aggagtaaaa     14640
     tcttgaaggt tcgaatcctt ccatctgtag gataaaaaat ctctaaaaga tttttcttag     14700
     ttaaaatctt aattgattac taaaaatact ctacaaaatt tttatatttt tttaaatgtt     14760
     tattacaagt cctttagaac aattcgaatt aaataattat ttcggtttct atctttttaa     14820
     ttaccatttt gatttctcta attttggttt ctatttaggt ttaagtgcat taattgctat     14880
     ttcattagca ataataaatt taacaccata tggatcagga gctaaaatag tacctcaaaa     14940
     atttggtata gcaatggaag ctatttattt tactatgtta aatttagttg aaaatcaaat     15000
     tcatagttca aaaactgtat caggacaaag ctatttccca ttcatttgga gtttatttgt     15060
     tttaatctta ttttctaatt tacttaggtt aattccttat ggttatgcta ctactgctca     15120
     attaatcttt actttaggtt taagtatttc tattttaatt ggtgctacta ttttaggatt     15180
     acaacaacat aaagctaaag tctttggatt attcttacct tctggtactc ctactccttt     15240
     aattcctctt ttagttttaa ttgaattcgt ttcttatatt gctagaggtt taagtttagg     15300
     tattcgatta ggtgctaata ttatagcagg tcatttaaca atgtcaattt taggaggttt     15360
     aatctttact ttcatgggat taaatcttat tacttttatt attggtttct tacctattac     15420
     agttttagtc gctatctctt tattagaatt tggtattgct tttattcaag cttatgtatt     15480
     cgctatttta acttgtggat tcattaatga tagtttaaac cttcactaat tttctccccc     15540
     tatttttatg gtgattgtaa ttcaatggta gaatgcttat ttgtggcata agaagttctt     15600
     ggttcgattc caagtaatca cccaatcaaa attatataac tctctttaaa aagtgtttaa     15660
     cggatagaaa catgtattgg ttcatgtact tgctttgggt gtgagaattt gttagttcga     15720
     atctaaccta tccgataata agtgattggg ttgttgacta ataggtaagt ccctgaaatt     15780
     tgacttcagt ctatgtaagt tcgaatctta ccatcccatt acttaaacat ctttaagatg     15840
     ttcctaaacc atccaaaaaa aaaacacttt attagtggga tggtctcttt tttatttaag     15900
     tatttccaaa atcaattagg aaccaattag ggtttcttaa atttctaatc aaaatgcaaa     15960
     aaaataattt aaaaaattta attactacta ttgtaactaa tgcttttttt aatcaaaaag     16020
     ctaatttttc aatacctctt aaaggtgtta ttggagaaaa aagaccatca atcttaatag     16080
     gaaatattaa tataaatttt aaaagtgatt ctttaattga agtatctttc ccttattatc     16140
     ctttacttaa taaaaattat ccaaatcctt caattataag taatattata caaaaagctc     16200
     tttcaaatca tcttttatat tcatctaaaa attactcttt tattgttaat attagagctc     16260
     ttcctatttc aactccttat ggaagtagtt taatcttttc aaaatatata gcaataataa     16320
     taggatcaaa tccaaaaata gcttctacat tatggataga tcctaaacga tttattaatt     16380
     tacccaaatt acaaagtgat tctatattta aaattttagg attaaatgta ccaaaaggat     16440
     ggaaaggtat tcatatctca ttaaatttaa ttaaatgaaa tagtctatca tcaagaggac     16500
     gaataactaa tataattaaa ggtagtgtac cattaacaaa taattctaat ggatatgatg     16560
     aaagttcttt agctatttat tctaaaatgg gtactattca aattaaggtt agattgtctt     16620
     attcttcaaa tctttaattg tttccccctt caatcattta aagttcttta acttaaaagg     16680
     tcagagtgca gacttgataa gtctgtggta ttggttcgat tccaataaga actagccaaa     16740
     taaattaatc cattacaata taattaatac cctttaaaag ttgtatggaa tttttcaatg     16800
     aagtaaaata actcccaaat ctttattttt ctttaaacct ttagtaacta tcaatttaaa     16860
     agtgaaaaag ataaaaaata aagaaaccct atagggttac tcaaatcatt aatatgccac     16920
     aattagtacc attctatttt attaatattt tatcttttgg ttttttaatc tttactgttt     16980
     tattatatat ttcatcagta tatgtattac caagatataa tgaattattt atctcaagat     17040
     ctattataag ttctttataa tttaacccct ccaaaagtat tgataatgtt cagtggtctg     17100
     aaattgaatt tgcaaaattt gatatatgag ttcaattctc atcattatct tttaccatat     17160
     ttattaggag aatagcttaa ttggtagagc acttacctta caagtaagat tataagggtt     17220
     caaatccctt ttctcctatt tcatctctaa aaaaaagggg agaattctta tgttggtttt     17280
     aagaggtgag ttgtagcctc attaggtcaa tcctatcgca ggttcgattc ctgctctcct     17340
     cattactcaa aagggagtaa aatcccctct ctcatctttt ttagttttaa ttaataataa     17400
     aatggcatcc ataactaatt tagtattgta aaagggaaaa tattttctta atatttattg     17460
     cacttttagc ttaattggtt agagtaacaa tcttcgaaat tgttagtata ggttcaaatc     17520
     ctataaagtg ttaatgaggt aaggattata gcttaacggt taaagcagag agctcataac     17580
     tcttgtatat tggttcgatt ccagtttgtc ctaatttatt tttcctcttt aattggaagg     17640
     gtgtccgagt ggtttaagga gcgatatttg agctattgtg atttattcat cgcaggttcg     17700
     aatcctgccc ctttcgaaag tctacagata aaaaaaatca catttctttt tgttagaata     17760
     gtaaactcta gctgtagaga gttaaattca tctaaatttt aaaatatgat acaagctgca     17820
     aaatacattg gtgctggttt agctacaatt ggtgttagtg gtgctggtgt tggtattgga     17880
     ttaatcttca gtaacttaat ctcaggtact tcaagaaacc catcagttcg acctcactta     17940
     ttctcaatgg ctatcctagg attcgcctta acagaagcta caggtttatt ctgtttaatg     18000
     ttagcgttct taattatcta cgctgcttaa tttccccctt taaaaaagag aatactgggg     18060
     atttaattta attggttaga atattgtgtt tgcaccacaa aaatctggtt tcgagtacca     18120
     gaatctccat tttccccctc caaaacattt tatttgaatg tttttaaact agaatctgtt     18180
     tgaagagaat ttgaataatt ctttggaaag tttggatcac tcataacatt agaatagtat     18240
     ttgtttaaag tggttaataa aaaagaaacc caagagggta agtctactaa tattaaagaa     18300
     agaagaattc agaattaaat tctgaaagtg ttaaaatagt agttcatttt taatttttag     18360
     taatttcaaa tataacagaa tccatcttat aagattccta gttggctcta ttgtctaatg     18420
     gttaagacct tacatcttca ttgtaaatat cttggttcga ttccaagtag ggctacttaa     18480
     ataataattt tgaaactatt acttttcgga tattatctta tttgttctca atttattatt     18540
     attaactcaa tgtgctctct atgttatttt ttaactctat attaaatgat gccccttcta     18600
     gctgggctct ttatttccaa gatggtgcat ctcctagtta tttaggtgta acacacttaa     18660
     atgattatct tatgttctat ctaactttca tctttatcgg tgtaatctat gctatctgta     18720
     aagctgttat agaatataat tacaatagcc atcctattgc tgcaaaatat acaactcatg     18780
     gttcaattgt tgaattcatt tggactttaa ttccagcttt aatcttaatt ttagttgctt     18840
     taccatcatt caaactttta tacttattag atgaagtaca aaaaccaagt atgactgtta     18900
     aggcaattgg aagacaatgg ttctggagtt atgaattaaa cgattttgtt actaatgaaa     18960
     atgaaccagt ttcatttgat agttatatgg taccagaaga agatttagaa gaaggtagtc     19020
     taagacaatt agaagtagat aatcgattag ttctacctat agatacacga ataagattaa     19080
     tcttaacaag tggtgatgtt atccatagtt gggctgttcc ttctttaggt ataaaatgtg     19140
     attgtatccc tagtagatta aatcaagttt ctttatctat tgatagagaa ggtttattct     19200
     acggacaatg tagtgaactt tgtggtgtac ttcattcatc tatgcctatt gttgttcaag     19260
     gtgtatctct tgaagatttc ttagcttggt tagaagaaaa ttcataacct cccccctaaa     19320
     gtgtttatta aatgatgaac tcaaatagag aataatcaag ttaaataata gtaagataag     19380
     tactaaatta gattttataa aattccaaag tataaatatt tttatatatg t              19431
//