format-version: 1.2
data-version: 40.0.
date: 21:03:2014 13:52
saved-by: midori
auto-generated-by: OBO-Edit 2.3
synonymtypedef: PRO-common-name "Label appended to organism-specific terms in place of scientific name" EXACT
synonymtypedef: PRO-short-label "Unique short label for PRO terms for display purposes" EXACT
synonymtypedef: PSI-MOD-label "Unique short label curated by PSI-MOD" EXACT
default-namespace: protein
remark: Use reasoner in obo edit to see the correct hierarchy.
ontology: pr

[Term]
id: PR:000000001
name: protein
def: "An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA." [PRO:DAN, PRO:WCB]
comment: Proteins descended from a common ancestor can be classified into families and superfamilies composed of products of evolutionarily-related genes. The domain architecture of a protein is described by the order of its constituent domains. Proteins with the same domains in the same order are defined as homeomorphic [PRO:WCB].
is_a: PR:000018263 ! amino acid chain

[Term]
id: PR:000003270
name: CDK2-related kinase
def: "A protein that is cyclin-dependent kinase. The activated form phosphorylates target substrates on Ser or Thr residues followed by a proline. The core domain architecture consists of a copy of the Protein kinase domain (PF00069)." [PRO:CNA]
comment: Category=family.
synonym: "kinase-related transforming protein" RELATED []
xref: PIRSF:PIRSF501117
is_a: PR:000000001 ! protein

[Term]
id: PR:000003271
name: cell division protein kinase 1
def: "A CDK2-related kinase that is a translation product of the human CDK1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "CDC2" RELATED []
synonym: "CDK1" EXACT PRO-short-label [PRO:DNx]
synonym: "Cell division control protein 2 homolog" EXACT []
synonym: "Cyclin-dependent kinase 1" EXACT []
synonym: "p34 protein kinase" EXACT []
is_a: PR:000003270 ! CDK2-related kinase

[Term]
id: PR:000004854
name: mitotic checkpoint serine/threonine-protein kinase BUB1
def: "A BUB1/BUB1B protein that is a translation product of the human BUB1 gene or a 1:1 ortholog thereof." [PMID:22698286, PRO:CNA]
comment: Category=gene.
synonym: "BUB1" EXACT PRO-short-label [PRO:DNx]
synonym: "BUB1A" EXACT []
synonym: "BUB1L" RELATED []
is_a: PR:000035665 ! BUB1/BUB1B protein

[Term]
id: PR:000004856
name: mitotic checkpoint protein BUB3
def: "A protein that is a translation product of the human BUB3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "BUB3" EXACT PRO-short-label [PRO:DNx]
synonym: "WD repeat type I transmembrane protein A72.5" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000005216
name: cell division cycle 5-like protein
def: "A protein that is a translation product of the human CDC5L gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "cdc5-like protein" EXACT []
synonym: "CDC5L" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0432" RELATED []
synonym: "PCDC5RP" RELATED []
synonym: "pombe cdc5-related protein" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000005418
name: serine/threonine-protein kinase Chk2
def: "A protein that is a translation product of the human CHEK2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "cds1" EXACT []
synonym: "CHEK2" EXACT PRO-short-label [PRO:DNx]
synonym: "CHK2" RELATED []
synonym: "RAD53" RELATED []
is_a: PR:000000001 ! protein

[Term]
id: PR:000010038
name: mitotic spindle assembly checkpoint protein MAD2A
def: "A protein that is a translation product of the human MAD2L1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "MAD2" RELATED []
synonym: "MAD2-like protein 1" EXACT []
synonym: "Mad2a" RELATED []
synonym: "MAD2L1" EXACT PRO-short-label [PRO:DNx]
synonym: "mitotic arrest deficient 2-like protein 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000010680
name: peptide methionine sulfoxide reductase
def: "A protein that is a translation product of the human MSRA gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "MSRA" EXACT PRO-short-label [PRO:DNx]
synonym: "MXR1" RELATED []
synonym: "peptide Met(O) reductase" EXACT []
synonym: "peptide-methionine (S)-S-oxide reductase" EXACT []
synonym: "PMSR" EXACT []
synonym: "protein-methionine-S-oxide reductase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000016558
name: tumor suppressor p53-binding protein 1
def: "A protein that is a translation product of the human TP53BP1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "53BP1" EXACT []
synonym: "p53-binding protein 1" EXACT []
synonym: "p53BP1" EXACT []
synonym: "TP53BP1" EXACT PRO-short-label [PRO:DNx]
synonym: "Trp53bp1" RELATED []
is_a: PR:000000001 ! protein

[Term]
id: PR:000016853
name: thioredoxin
def: "A protein that is a translation product of the human TXN gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ADF" RELATED []
synonym: "ATL-derived factor" EXACT []
synonym: "SASP" EXACT []
synonym: "surface-associated sulphydryl protein" EXACT []
synonym: "TRDX" RELATED []
synonym: "Trx" EXACT []
synonym: "TRX1" RELATED []
synonym: "TXN" EXACT PRO-short-label [PRO:DNx]
synonym: "Txn1" RELATED []
is_a: PR:000000001 ! protein

[Term]
id: PR:000018263
name: amino acid chain
def: "A molecular entity that is a polymer of amino acids linked by peptide bonds." [PRO:DAN]
synonym: "peptide" NARROW []
synonym: "polypeptide" NARROW []

[Term]
id: PR:000018264
name: proteolytic cleavage product
def: "An amino acid chain produced as the result of peptide bond cleavage of a longer amino acid chain." [PRO:DAN]
synonym: "peptide" NARROW []
synonym: "polypeptide" NARROW []
is_a: PR:000018263 ! amino acid chain

[Term]
id: PR:000021935
name: immature protein part
def: "A part of a protein that is removed during the protein maturation process." [PRO:DAN]
synonym: "cleaved_peptide_region" EXACT [SO:0100011]

[Term]
id: PR:000021937
name: initiator methionine
def: "An immature protein part that is the N-terminal most residue." [PRO:DAN]
comment: The initiator methionine is cleaved co-translationally. For this reason, we do not use the derives_from relation when defining protein forms lacking the initiator (because the precursor form does not yet exist at the time of removal).
is_a: PR:000021935 ! immature protein part

[Term]
id: PR:000024854
name: P-factor precursor
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- map2 gene or a 1:1 ortholog thereof. In Schizosaccharomyces pombe, proteolytic processing yeilds four peptides - two copies of P-factor 1 and one each of P-factor 2 and P-factor 3." [PMID:8314086, PRO:MSY]
comment: Category=gene. Requested by=PomBase.
synonym: "map2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000024855
name: P-factor
def: "A proteolytic cleavage product that is derived from P-factor precursor. In Schizosaccharomyces pombe 972h- the sequence is TYADFLRAYQSWNTFVNPDRPNL, corresponding to amino acids 66-88 or 134-156 of UniProtKB:Q09180-1." [PRO:MSY]
comment: Category=modification. Requested by=PomBase.
is_a: PR:000018264 ! proteolytic cleavage product

[Term]
id: PR:000024856
name: P-factor-like 1
def: "A proteolytic cleavage product that is derived from P-factor precursor. In Schizosaccharomyces pombe 972h- the sequence is SYADFLRVYQSWNTFANPDRPNL, corresponding to amino acids 32-54 of UniProtKB:Q09180-2." [PRO:MSY]
comment: Category=modification. Requested by=PomBase.
is_a: PR:000018264 ! proteolytic cleavage product

[Term]
id: PR:000024857
name: P-factor-like 2
def: "A proteolytic cleavage product that is derived from P-factor precursor. In Schizosaccharomyces pombe 972h- the sequence is SYADFLRAYHSWNTFVNPDRPNL, corresponding to amino acids 100-122 of UniProtKB:Q09180-3." [PRO:MSY]
comment: Category=modification. Requested by=PomBase.
is_a: PR:000018264 ! proteolytic cleavage product

[Term]
id: PR:000024858
name: inactivated P-factor
def: "A proteolytic cleavage product derived from P-factor by removal of the C-terminal leucine residue." [PMID:10792724, PRO:MSY]
comment: Category=modification. Requested by=PomBase.
is_a: PR:000018264 ! proteolytic cleavage product

[Term]
id: PR:000024934
name: dma1 homodimer (fission yeast)
def: "A ubiquitin ligase complex composed of two subunits of fission yeast E3 ubiquitin-protein ligase dma1." [PMID:22669973, PRO:DAN]
comment: Category=organism-complex. Requested by=PomBase.

[Term]
id: PR:000025000
name: M-factor precursor
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- mfm1, mfm2, or mfm3 genes or 1:1 orthologs thereof." [PRO:MSY]
comment: Category=union. Requested by=PomBase.
is_a: PR:000000001 ! protein

[Term]
id: PR:000025001
name: M-factor
def: "A proteolytic cleavage product that is derived from propeptide removal from M-factor precursor, farnesylated 1. In Schizosaccharomyces pombe 972h- the sequence is YTPKVPYMC, with a farnesylated C-terminal residue." [PMID:1547790, PMID:8196631, PRO:MSY]
comment: Category=union. Requested by=PomBase.
is_a: PR:000018264 ! proteolytic cleavage product

[Term]
id: PR:000025002
name: M-factor precursor, farnesylated 1
def: "An M-factor precursor that is farnesylated at the C-terminal-most cysteine residue." [PRO:MSY]
comment: Category=modification. Requested by=PomBase.
is_a: PR:000024857 ! P-factor-like 2

[Term]
id: PR:000025003
name: M-factor precursor mfm1
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- mfm1 gene or a 1:1 ortholog thereof." [PRO:MSY]
comment: Category=gene. Requested by=PomBase.
synonym: "mfm1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000025000 ! M-factor precursor

[Term]
id: PR:000025004
name: M-factor precursor mfm2
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- mfm2 gene or a 1:1 ortholog thereof." [PRO:MSY]
comment: Category=gene. Requested by=PomBase.
synonym: "mfm2" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000025000 ! M-factor precursor

[Term]
id: PR:000025005
name: M-factor precursor mfm3
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- mfm3 gene or a 1:1 ortholog thereof." [PRO:MSY]
comment: Category=gene. Requested by=PomBase.
synonym: "mfm3" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000025000 ! M-factor precursor

[Term]
id: PR:000025513
name: modified amino-acid residue
def: "An amino-acid residue that is covalently modified by chemical alteration to the side chain or backbone atoms." [PRO:DAN]
comment: Category=external.
synonym: "modified amino acid chain residue" EXACT [PRO:DAN]
synonym: "modified protein residue" NARROW [PRO:DAN]

[Term]
id: PR:000027125
name: cell division protein kinase 1 phosphorylated form
def: "A cell division protein kinase 1 that has been post-translationally modified to include at least one phosphorylated residue." [PRO:DAN]
comment: Category=modification.
synonym: "CDK1/PhosRes+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003271 ! cell division protein kinase 1
is_a: PR:000037070 ! phosphoprotein

[Term]
id: PR:000027498
name: p38-like stress-activated mitogen-activated protein kinase
def: "A protein that contains a single copy of the Protein kinase domain (PF00069) and is a fungal mitogen-activated protein kinase activated when cells are challenged with a variety of environmental stresses, such as osmotic, oxidative, and heat stress." [KinBase:p38, PMID:10207620, PRO:CNA]
comment: Category=family.
synonym: "HOG1-like map kinase" EXACT []
synonym: "HOG1-like mitogen-activated protein kinase" EXACT []
synonym: "p38 subfamily of MAPK" RELATED []
synonym: "SAPK" RELATED []
xref: PIRSF:PIRSF501111
is_a: PR:000000001 ! protein

[Term]
id: PR:000027499
name: mitogen-activated protein kinase HOG1
def: "A p38-like stress-activated mitogen-activated protein kinase that is a translation product of the yeast HOG1 gene or a 1:1 ortholog thereof." [PMID:10207620, PRO:CNA]
comment: Category=gene. The gene HOG1 in S. pombe is named sty1.
synonym: "HOG1" EXACT PRO-short-label [PRO:DNx]
synonym: "MAP kinase spc1" EXACT []
synonym: "STY1" RELATED []
is_a: PR:000027498 ! p38-like stress-activated mitogen-activated protein kinase

[Term]
id: PR:000027501
name: mitogen-activated protein kinase HOG1 phosphorylated form
def: "A mitogen-activated protein kinase HOG1 that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "HOG1/PhosRes+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027499 ! mitogen-activated protein kinase HOG1
is_a: PR:000037070 ! phosphoprotein

[Term]
id: PR:000027502
name: mitogen-activated protein kinase HOG1 phosphorylated 1
def: "A mitogen-activated protein kinase HOG1 phosphorylated form that has been phosphorylated at the Thr and Tyr residues of the MAP kinase activation motif TxY." [PMID:20729203, PRO:CNA]
comment: Category=modification.
synonym: "active HOG1" EXACT []
synonym: "HOG1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027501 ! mitogen-activated protein kinase HOG1 phosphorylated form

[Term]
id: PR:000027503
name: mitogen-activated protein kinase sty1 phosphorylated 1 (fission yeast)
def: "A mitogen-activated protein kinase sty1 phosphorylated 1 in Schizosaccharomyces pombe. Phosphorylated on TxY motif by MAPK kinase (Wis1). Example: UniProtKB:Q09892-1, Thr-171, MOD:00047|Tyr-173, MOD:00048." [PMID:20729203, PMID:7501024, PMID:9251044, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "active PHH1" EXACT []
synonym: "active spc1" EXACT []
synonym: "active sty1" EXACT []
synonym: "Spom-HOG1/Phos:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027502 ! mitogen-activated protein kinase HOG1 phosphorylated 1

[Term]
id: PR:000027504
name: mitogen-activated protein kinase HOG1 unmodified form
def: "A mitogen-activated protein kinase HOG1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification.
synonym: "HOG1/UnMod" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027499 ! mitogen-activated protein kinase HOG1

[Term]
id: PR:000027505
name: mitogen-activated protein kinase sty1 unmodified form (fission yeast)
def: "A mitogen-activated protein kinase HOG1 unmodified form in Schizosaccharomyces pombe." [PRO:CNA]
comment: Category=organism-modification.
synonym: "Spom-HOG1/UnMod" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027504 ! mitogen-activated protein kinase HOG1 unmodified form

[Term]
id: PR:000027506
name: M-phase inducer phosphatase
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- cdc25 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. CDC25 is named MIH1 in yeast.
synonym: "CDC25" RELATED []
synonym: "cdc25" EXACT PRO-short-label [PRO:DNx]
synonym: "MIH1" RELATED []
synonym: "Mitosis initiation protein" EXACT []
synonym: "P80" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000027508
name: M-phase inducer phosphatase unmodified form
def: "An M-phase inducer phosphatase that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification.
synonym: "cdc25/UnMod" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027506 ! M-phase inducer phosphatase

[Term]
id: PR:000027509
name: M-phase inducer phosphatase unmodified form (fission yeast)
def: "An M-phase inducer phosphatase unmodified form in Schizosaccharomyces pombe." [PMID:9774107, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-cdc25/UnMod" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027508 ! M-phase inducer phosphatase unmodified form

[Term]
id: PR:000027510
name: M-phase inducer phosphatase phosphorylated form
def: "An M-phase inducer phosphatase that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "cdc25/PhosRes+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027506 ! M-phase inducer phosphatase
is_a: PR:000037070 ! phosphoprotein

[Term]
id: PR:000027511
name: M-phase inducer phosphatase phosphorylated 1
def: "An M-phase inducer phosphatase phosphorylated form that has been phosphorylated at the Ser residues within the canonical 14-3-3 binding motifs. Example: UniProtKB:P06652-1, Ser-99/Ser-192/Ser-359, MOD:00046." [PMID:9774107, PRO:CNA]
comment: Category=modification.
synonym: "cdc25/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027510 ! M-phase inducer phosphatase phosphorylated form

[Term]
id: PR:000027512
name: M-phase inducer phosphatase phosphorylated 1 (fission yeast)
def: "An M-phase inducer phosphatase phosphorylated 1 in Schizosaccharomyces pombe. This form is produced by phosphorylation by Cds1 or Chk1 during replication checkpoint. Example: UniProtKB:P06652-1, Ser-99/Ser-192/Ser-359, MOD:00046." [PMID:9774107, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase. Ser-192 is a minor phosphorylation site.
synonym: "Spom-cdc25/Phos:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027511 ! M-phase inducer phosphatase phosphorylated 1

[Term]
id: PR:000027513
name: transcriptional regulator prz1
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- prz1 gene or a 1:1 ortholog thereof." [PMID:12637524, PRO:CNA]
comment: Category=gene.
synonym: "Pbp1-responsive zinc finger protein 1" EXACT []
synonym: "prz1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000027515
name: transcriptional regulator prz1 unmodified form
def: "A transcriptional regulator prz1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification.
synonym: "prz1/UnMod" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027513 ! transcriptional regulator prz1

[Term]
id: PR:000027516
name: transcriptional regulator prz1 unmodified form (fission yeast)
def: "A transcriptional regulator prz1 unmodified form in Schizosaccharomyces pombe." [PMID:12637524, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-prz1/UnMod" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027515 ! transcriptional regulator prz1 unmodified form

[Term]
id: PR:000027517
name: anaphase spindle elongation protein 1
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- ase1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "ase1" EXACT PRO-short-label [PRO:DNx]
synonym: "Ase1p" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000027519
name: anaphase spindle elongation protein 1 unmodified form
def: "An anaphase spindle elongation protein 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification.
synonym: "ase1/UnMod" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027517 ! anaphase spindle elongation protein 1

[Term]
id: PR:000027520
name: anaphase spindle elongation protein 1 unmodified form (fission yeast)
def: "An anaphase spindle elongation protein 1 unmodified form in Schizosaccharomyces pombe." [PMID:19686686, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-ase1/UnMod" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027519 ! anaphase spindle elongation protein 1 unmodified form

[Term]
id: PR:000027521
name: anaphase spindle elongation protein 1 phosphorylated 1
def: "An anaphase spindle elongation protein 1 phosphorylated form that has been modified on cdc2-dependent phosphorylation sites. Example: UniProtKB:Q9HDY1-1, Ser-640/Ser-683/Ser-688/Ser-693, MOD:00046." [PMID:19686686, PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "ase1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027531 ! anaphase spindle elongation protein 1 phosphorylated form

[Term]
id: PR:000027522
name: anaphase spindle elongation protein 1 phosphorylated 1 (fission yeast)
def: "An anaphase spindle elongation protein 1 phosphorylated 1 in Schizosaccharomyces pombe. Example: UniProtKB:Q9HDY1-1, Ser-640/Ser-683/Ser-688/Ser-693, MOD:00046." [PMID:18257517, PMID:19686686, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-ase1/Phos:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027521 ! anaphase spindle elongation protein 1 phosphorylated 1

[Term]
id: PR:000027523
name: DNA replication regulator sld2
def: "A protein that is a translation product of the yeast SLD2 gene or a 1:1 ortholog thereof." [PMID:11937031, PRO:CNA]
comment: Category=gene. In Schizosaccharomyces pombe 972h- SLD2 is called DRC1.
synonym: "DNA replication and checkpoint protein 1" EXACT []
synonym: "DRC1" RELATED []
synonym: "SLD2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000027525
name: DNA replication regulator sld2 unmodified form
def: "A DNA replication regulator sld2 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification.
synonym: "SLD2/UnMod" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027523 ! DNA replication regulator sld2

[Term]
id: PR:000027526
name: DNA replication regulator sld2 unmodified form (fission yeast)
def: "A DNA replication regulator sld2 unmodified form in Schizosaccharomyces pombe." [PMID:11937031, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "DNA replication regulator drc1 unmodified form (fission yeast)" EXACT []
synonym: "Spom-SLD2/UnMod" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027525 ! DNA replication regulator sld2 unmodified form

[Term]
id: PR:000027527
name: DNA replication regulator sld2 phosphorylated form
def: "A DNA replication regulator sld2 that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "SLD2/PhosRes+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027523 ! DNA replication regulator sld2
is_a: PR:000037070 ! phosphoprotein

[Term]
id: PR:000027528
name: DNA replication regulator sld2 phosphorylated 1
def: "A DNA replication regulator sld2 phosphorylated form that has been phosphorylated on the [ST]P[KR][KR] cyclin-dependent kinase motifs. Example: UniProtKB:O14216-1, Thr-60/Thr-74/Thr-99/Thr-154, MOD:00047|Ser-87, MOD:00046." [PMID:11937031, PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "SLD2/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027527 ! DNA replication regulator sld2 phosphorylated form

[Term]
id: PR:000027529
name: DNA replication regulator sld2 phosphorylated 1 (fission yeast)
def: "A DNA replication regulator sld2 phosphorylated 1 in Schizosaccharomyces pombe. Example: UniProtKB:O14216-1, Thr-60/Thr-74/Thr-99/Thr-154, MOD:00047|Ser-87, MOD:00046." [PMID:11937031, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "DNA replication regulator drc1 phosphorylated 1" EXACT []
synonym: "Spom-SLD2/Phos:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027528 ! DNA replication regulator sld2 phosphorylated 1

[Term]
id: PR:000027530
name: transcriptional regulator prz1 phosphorylated form
def: "A transcriptional regulator prz1 phosphorylated form that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "prz1/PhosRes+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027513 ! transcriptional regulator prz1
is_a: PR:000037070 ! phosphoprotein

[Term]
id: PR:000027531
name: anaphase spindle elongation protein 1 phosphorylated form
def: "An anaphase spindle elongation protein 1 that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "ase1/PhosRes+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027517 ! anaphase spindle elongation protein 1

[Term]
id: PR:000027532
name: transcriptional regulator prz1 phosphorylated 1
def: "A transcriptional regulator prz1 phosphorylated form that is hyperphosphorylated under conditions where calcineurin is not active." [PMID:12637524, PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "prz1 hyperphosphorylated" EXACT []
synonym: "prz1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027530 ! transcriptional regulator prz1 phosphorylated form

[Term]
id: PR:000027533
name: transcriptional regulator prz1 isoform 1 phosphorylated 1 (fission yeast)
def: "A transcriptional regulator prz1 phosphorylated 1 in Schizosaccharomyces pombe. Example: UniProtKB:Q09838-1, MOD:00696." [PMID:12637524, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-prz1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027532 ! transcriptional regulator prz1 phosphorylated 1

[Term]
id: PR:000027538
name: transcription factor ste11
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- ste11 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "STE11" RELATED []
synonym: "ste11" EXACT PRO-short-label [PRO:DNx]
synonym: "STEX" RELATED []
is_a: PR:000000001 ! protein

[Term]
id: PR:000027540
name: transcription factor ste11 unmodified form
def: "A transcription factor ste11 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification.
synonym: "ste11/UnMod" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027538 ! transcription factor ste11

[Term]
id: PR:000027541
name: transcription factor ste11 unmodified form (fission yeast)
def: "A transcription factor ste11 unmodified form unmodified form in Schizosaccharomyces pombe." [PMID:11702950, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-ste11/UnMod" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027540 ! transcription factor ste11 unmodified form

[Term]
id: PR:000027542
name: transcription factor ste11 phosphorylated 1
def: "A transcription factor ste11 phosphorylated form that has been phosphorylated at the consensus recognition sequence for 14-3-3. Example: UniProtKB:P36631-1, Thr-173, MOD:00047|Ser-218, MOD:00046." [PMID:11702950, PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "ste11/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027544 ! transcription factor ste11 phosphorylated form

[Term]
id: PR:000027543
name: transcription factor ste11 phosphorylated 1 (fission yeast)
def: "A transcription factor ste11 phosphorylated 1 in Schizosaccharomyces pombe. Phosphorylated by Pat1 kinase. Example: UniProtKB:P36631-1, Thr-173, MOD:00047|Ser-218, MOD:00046." [PMID:11702950, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-ste11/Phos:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027542 ! transcription factor ste11 phosphorylated 1

[Term]
id: PR:000027544
name: transcription factor ste11 phosphorylated form
def: "A transcription factor ste11 that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "ste11/PhosRes+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027538 ! transcription factor ste11
is_a: PR:000037070 ! phosphoprotein

[Term]
id: PR:000027545
name: histone H2A.2
def: "A histone H2A that is a translation product of the yeast HTA2 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. Requested by=PomBase. This protein is called histone H2A-beta in Schizosaccharomyces pombe.
synonym: "H2A.2" EXACT []
synonym: "H2A2" RELATED []
synonym: "HTA2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027547 ! histone H2A

[Term]
id: PR:000027547
name: histone H2A
def: "A protein that is a translational product of one of the H2A gene variants. It is a core histone and contains a copy of the Histone (PF00125) domain." [PMID:18443735, PMID:19234519, PRO:CNA]
comment: Category=family. Requested by=PomBase.
xref: PIRSF:PIRSF002048
is_a: PR:000000001 ! protein

[Term]
id: PR:000027548
name: histone H2A.2 unmodified form
def: "A histone H2A.2 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "HTA2/UnMod" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027545 ! histone H2A.2

[Term]
id: PR:000027549
name: histone H2A-beta unmodified form (fission yeast)
def: "A histone H2A.2 unmodified form in Schizosaccharomyces pombe." [PMID:15226425, PMID:19965387, PMID:21516229, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-HTA2/UnMod" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027548 ! histone H2A.2 unmodified form

[Term]
id: PR:000027550
name: histone H2A.2 phosphorylated 1
def: "A histone H2A.2 phosphorylated form that has been phosphorylated on the [ST]Q motif at the C-terminus that constitutes a recognition sequence for kinases from the PI3/PI4-kinase family. Phosphorylated in response to DNA double-strand breaks generated by exogenous genotoxic agents and by stalled replication forks. Example: UniProtKB:P04910-1, Ser-128, MOD:00046." [PMID:15226425, PMID:21516229, PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "gamma-H2A" RELATED []
synonym: "H2AS128ph" RELATED []
synonym: "HTA2/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027552 ! histone H2A.2 phosphorylated form

[Term]
id: PR:000027551
name: histone H2A-beta phosphorylated 1 (fission yeast)
def: "A histone H2A.2 phosphorylated 1 in Schizosaccharomyces pombe. Phosphorylation motif is SQE. Example: UniProtKB:P04910-1, Ser-128, MOD:00046." [PMID:15226425, PMID:21516229, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "gamma-H2A (fission yeast)" RELATED []
synonym: "histone H2A.2 phosphorylated 1 (fission yeast)" EXACT []
synonym: "Spom-HTA2/Phos:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027550 ! histone H2A.2 phosphorylated 1

[Term]
id: PR:000027552
name: histone H2A.2 phosphorylated form
def: "A histone H2A.2 that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "HTA2/PhosRes+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027545 ! histone H2A.2
is_a: PR:000037070 ! phosphoprotein

[Term]
id: PR:000027553
name: histone H2A.2 phosphorylated 1 (yeast)
def: "A histone H2A.2 phosphorylated 1 in yeast. Phosphorylation motif is SQE. UniProtKB:P04912-1, Ser-129, MOD:00046." [PMID:11140636, PRO:CNA]
comment: Category=organism-modification.
synonym: "gamma-H2A (yeast)" RELATED []
synonym: "yHTA2/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027550 ! histone H2A.2 phosphorylated 1
is_a: PR:P04912 ! histone H2A.2 (yeast)

[Term]
id: PR:000027554
name: histone H2A.2 unmodified form (yeast)
def: "A histone H2A.2 unmodified form in yeast." [PMID:11140636, PRO:CNA]
comment: Category=organism-modification.
synonym: "yHTA2/UnMod" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027548 ! histone H2A.2 unmodified form
is_a: PR:P04912 ! histone H2A.2 (yeast)

[Term]
id: PR:000027556
name: histone H2A.2 phosphorylated 2
def: "A histone H2A-beta phosphorylated form that has been phosphorylated at the Ser or Thr residue within the LLPKx[ST] motif by the mitotic checkpoint serine/threonine-protein kinase BUB1. Example: UniProtKB:P04910-1, Ser-122, MOD:00046." [PMID:19965387, PRO:CNA]
comment: Category=modification.
synonym: "HTA2/Phos:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027552 ! histone H2A.2 phosphorylated form

[Term]
id: PR:000027557
name: histone H2A-beta phosphorylated 2 (fission yeast)
def: "A histone H2A.2 phosphorylated 2 in Schizosaccharomyces pombe. Example: UniProtKB:P04910-1, Ser-122, MOD:00046." [PMID:19965387, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-HTA2/Phos:2" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027556 ! histone H2A.2 phosphorylated 2

[Term]
id: PR:000027558
name: histone H2A-alpha
def: "A histone H2A that is a translation product of the Schizosaccharomyces pombe 972h- hta1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. Requested by=PomBase. This protein is called histone H2A-alpha in Schizosaccharomyces pombe.
synonym: "H2A.1" BROAD []
synonym: "hta1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027547 ! histone H2A

[Term]
id: PR:000027560
name: histone H2A-alpha unmodified form
def: "A histone H2A.1 which lacks phosphorylated residues." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "hta1/UnMod" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027558 ! histone H2A-alpha

[Term]
id: PR:000027561
name: histone H2A-alpha unmodified form (fission yeast)
def: "A histone H2A-alpha unmodified form in Schizosaccharomyces pombe." [PMID:15226425, PMID:19965387, PMID:21516229, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-hta1/UnMod" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027560 ! histone H2A-alpha unmodified form

[Term]
id: PR:000027562
name: histone H2A-alpha phosphorylated form
def: "A histone H2A-alpha that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "histone H2A.1 phosphorylated form" EXACT []
synonym: "hta1/PhosRes+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027558 ! histone H2A-alpha
is_a: PR:000037070 ! phosphoprotein

[Term]
id: PR:000027563
name: histone H2A-alpha phosphorylated 1
def: "A histone H2A-alpha phosphorylated form that has been phosphorylated on the [ST]Q motif at the C-terminus that constitutes a recognition sequence for kinases from the PI3/PI4-kinase family. Phosphorylated in response to DNA double-strand breaks generated by exogenous genotoxic agents and by stalled replication forks. Example: UniProtKB:P04909-1, Ser-129, MOD:00046." [PMID:15226425, PMID:21516229, PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "gamma-H2A" RELATED []
synonym: "H2AS128ph" RELATED []
synonym: "histone H2A.1 phosphorylated 1" EXACT []
synonym: "hta1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027562 ! histone H2A-alpha phosphorylated form

[Term]
id: PR:000027564
name: histone H2A-alpha phosphorylated 1 (fission yeast)
def: "A histone H2A-alpha phosphorylated 1 in Schizosaccharomyces pombe. Phosphorylation motif is SQE. Example: UniProtKB:P04909-1, Ser-129, MOD:00046." [PMID:15226425, PMID:21516229, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "gamma-H2A (fission yeast)" RELATED []
synonym: "histone H2A.1 phosphorylated 1 (fission yeast)" EXACT []
synonym: "Spom-hta1/Phos:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027563 ! histone H2A-alpha phosphorylated 1

[Term]
id: PR:000027565
name: histone H2A-alpha phosphorylated 2
def: "A histone H2A.1 phosphorylated form that has been phosphorylated at the Ser or Thr residue within the LLPKx[ST] motif by the mitotic checkpoint serine/threonine-protein kinase BUB1. Example: UniProtKB:P04909-1, Ser-122, MOD:00046." [PMID:19965387, PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "histone H2A.1 phosphorylated 2" EXACT []
synonym: "hta1/Phos:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027562 ! histone H2A-alpha phosphorylated form

[Term]
id: PR:000027566
name: histone H2A-alpha phosphorylated 2 (fission yeast)
def: "A histone H2A-alpha phosphorylated 2 in Schizosaccharomyces pombe. Example: UniProtKB:P04909-1, Ser-122, MOD:00046." [PMID:19965387, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "histone H2A.1 phosphorylated 2 (fission yeast)" EXACT []
synonym: "Spom-hta1/Phos:2" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027565 ! histone H2A-alpha phosphorylated 2

[Term]
id: PR:000027567
name: meiosis protein mei2
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- mei2 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. Requested by=PomBase.
synonym: "mei2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000027569
name: histone H3.1
def: "A histone H3 that is a translation product of the Schizosaccharomyces pombe 972h- hht1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. Requested by=PomBase.
synonym: "hht1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027594 ! histone H3

[Term]
id: PR:000027570
name: histone H3.1 (fission yeast)
def: "A histone H3.1 that is encoded in the genome of fission yeast." [PMID:11242054, PMID:20929775, PomBase:MAH]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "SPAC1834.04" RELATED []
synonym: "Spom-hht1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027569 ! histone H3.1

[Term]
id: PR:000027571
name: fungal histone H3.2
def: "A histone H3 that is a translation product of the Schizosaccharomyces pombe 972h- hht2 gene or a 1:1 ortholog thereof." [PMID:11242054, PMID:20929775, PRO:CNA]
comment: Category=gene. Requested by=PomBase.
synonym: "hht2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027594 ! histone H3

[Term]
id: PR:000027572
name: histone H3.2 (fission yeast)
def: "A histone H3.2 that is encoded in the genome of fission yeast." [PMID:11242054, PMID:20929775, PomBase:MAH]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "SPBC8D2.04, PI060" RELATED []
synonym: "Spom-hht2" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027571 ! fungal histone H3.2

[Term]
id: PR:000027573
name: histone H3.1, initiator methionine removed form
def: "A histone H3.1 that has had the initiator methionine removed." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "hht1/InitMet-" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027569 ! histone H3.1

[Term]
id: PR:000027574
name: histone H3.1, initiator methionine removed form (fission yeast)
def: "A histone H3.1, initiator methionine removed form in Schizosaccharomyces pombe." [PMID:11242054, PMID:20929775, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-hht1/InitMet-" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027570 ! histone H3.1 (fission yeast)
is_a: PR:000027573 ! histone H3.1, initiator methionine removed form

[Term]
id: PR:000027575
name: histone H3.1, initiator methionine removed phosphorylated 1
def: "A histone H3.1, initiator methionine removed form which has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "H3-pT3" RELATED []
synonym: "hht1/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027573 ! histone H3.1, initiator methionine removed form

[Term]
id: PR:000027576
name: histone H3.1, initiator methionine removed phosphorylated 1 (fission yeast)
def: "A histone H3.1, initiator methionine removed phosphorylated 1 in Schizosaccharomyces pombe. Phosphorylated by Haspin. Example: UniProtKB:P09988-1, 2-136, Thr-4, MOD:00047." [PMID:20929775, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase. Note that this form is referred to as H3-pT3, because the initial methionine is not counted.
synonym: "H3-pT3" RELATED []
synonym: "Spom-hht1/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027574 ! histone H3.1, initiator methionine removed form (fission yeast)
is_a: PR:000027575 ! histone H3.1, initiator methionine removed phosphorylated 1

[Term]
id: PR:000027577
name: histone H3.1, initiator methionine removed methylated 1
def: "A histone H3.1, initiator methionine removed which has at least one methylated residue." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "hht1/InitMet-/Me:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027573 ! histone H3.1, initiator methionine removed form

[Term]
id: PR:000027578
name: histone H3.1, initiator methionine removed methylated 1 (fission yeast)
def: "A histone H3.1, initiator methionine removed methylated 1 in Schizosaccharomyces pombe. Methylated by HP1. Example: UniProtKB:P09988-1, 2-136, Lys-10, MOD:00663." [PMID:11242054, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase. Note that in the article cited residue number is different because the initial methionine is not counted.
synonym: "Spom-hht1/InitMet-/Me:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027574 ! histone H3.1, initiator methionine removed form (fission yeast)
is_a: PR:000027577 ! histone H3.1, initiator methionine removed methylated 1

[Term]
id: PR:000027579
name: histone H3.2, initiator methionine removed form
def: "A histone H3.2 that has had the initiator methionine removed." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "hht2/InitMet-" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027571 ! fungal histone H3.2

[Term]
id: PR:000027580
name: histone H3.2, initiator methionine removed form (fission yeast)
def: "A histone H3.2, initiator methionine removed form in Schizosaccharomyces pombe." [PMID:11242054, PMID:20929775, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-hht2/InitMet-" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027572 ! histone H3.2 (fission yeast)
is_a: PR:000027579 ! histone H3.2, initiator methionine removed form

[Term]
id: PR:000027581
name: histone H3.1, initiator methionine removed unphosphorylated form
def: "A histone H3.1, initiator methionine removed which lacks phosphorylated residues." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "hht1/InitMet-/PhosRes-" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027573 ! histone H3.1, initiator methionine removed form

[Term]
id: PR:000027582
name: meiosis protein mei2 unmodified form
def: "A meiosis protein mei2 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "mei2/UnMod" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027567 ! meiosis protein mei2

[Term]
id: PR:000027583
name: meiosis protein mei2 unmodified form (fission yeast)
def: "A meiosis protein mei2 unmodified form in Schizosaccharomyces pombe." [PMID:9062192, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-mei2/UnMod" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027582 ! meiosis protein mei2 unmodified form

[Term]
id: PR:000027584
name: meiosis protein mei2 phosphorylated form
def: "A meiosis protein mei2 that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "mei2/PhosRes+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027567 ! meiosis protein mei2
is_a: PR:000037070 ! phosphoprotein

[Term]
id: PR:000027585
name: meiosis protein mei2 phosphorylated 1
def: "A meiosis protein mei2 phosphorylated form that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "mei2/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027584 ! meiosis protein mei2 phosphorylated form

[Term]
id: PR:000027586
name: meiosis protein mei2 phosphorylated 1 (fission yeast)
def: "A meiosis protein mei2 phosphorylated 1 in Schizosaccharomyces pombe. Phosphorylated by Pat1 kinase. Example: UniProtKB:P08965-1, Ser-438, MOD:00046|Thr-527, MOD:00047." [PMID:9062192, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-mei2/Phos:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027585 ! meiosis protein mei2 phosphorylated 1

[Term]
id: PR:000027587
name: histone H3.1, initiator methionine removed unphosphorylated form (fission yeast)
def: "A histone H3.1, initiator methionine removed unphosphorylated form in Schizosaccharomyces pombe. Example: UniProtKB:P09988-1, 2-136." [PMID:11242054, PMID:20929775, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-hht1/InitMet-/PhosRes-" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027574 ! histone H3.1, initiator methionine removed form (fission yeast)
is_a: PR:000027581 ! histone H3.1, initiator methionine removed unphosphorylated form

[Term]
id: PR:000027588
name: histone H3.2, initiator methionine removed unphosphorylated form
def: "A histone H3.2, initiator methionine removed which lacks phosphorylated residues." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "hht2/InitMet-/PhosRes-" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027579 ! histone H3.2, initiator methionine removed form

[Term]
id: PR:000027589
name: histone H3.2, initiator methionine removed unphosphorylated form (fission yeast)
def: "A histone H3.2, initiator methionine removed unphosphorylated form in Schizosaccharomyces pombe. Example: UniProtKB:P09988-1, 2-136." [PMID:11242054, PMID:20929775, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-hht2/InitMet-/PhosRes-" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027580 ! histone H3.2, initiator methionine removed form (fission yeast)
is_a: PR:000027588 ! histone H3.2, initiator methionine removed unphosphorylated form

[Term]
id: PR:000027590
name: histone H3.2, initiator methionine removed phosphorylated 1
def: "A histone H3.2, initiator methionine removed form which has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "H3-pT3" RELATED []
synonym: "hht2/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027579 ! histone H3.2, initiator methionine removed form

[Term]
id: PR:000027591
name: histone H3.2, initiator methionine removed phosphorylated 1 (fission yeast)
def: "A histone H3.2, initiator methionine removed phosphorylated 1 in Schizosaccharomyces pombe. Phosphorylated by Haspin. Example: UniProtKB:P09988-1, 2-136, Thr-4, MOD:00047." [PMID:20929775, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase. Note that this form is referred to as H3-pT3, because the initial methionine is not counted.
synonym: "H3-pT3" RELATED []
synonym: "Spom-hht2/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027580 ! histone H3.2, initiator methionine removed form (fission yeast)
is_a: PR:000027590 ! histone H3.2, initiator methionine removed phosphorylated 1

[Term]
id: PR:000027592
name: histone H3.2, initiator methionine removed methylated 1
def: "A histone H3.2, initiator methionine removed which has at least one methylated residue." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "hht2/InitMet-/Me:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027579 ! histone H3.2, initiator methionine removed form

[Term]
id: PR:000027593
name: histone H3.2, initiator methionine removed methylated 1 (fission yeast)
def: "A histone H3.2, initiator methionine removed methylated 1 in Schizosaccharomyces pombe. Methylated by HP1. Example: UniProtKB:P09988-1, 2-136, Lys-10, MOD:00663." [PMID:11242054, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase. Note that in the article cited residue number is different because the initial methionine is not counted.
synonym: "Spom-hht2/InitMet-/Me:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027580 ! histone H3.2, initiator methionine removed form (fission yeast)
is_a: PR:000027592 ! histone H3.2, initiator methionine removed methylated 1

[Term]
id: PR:000027594
name: histone H3
def: "A protein that is a translational product of one of the H3 gene variants. It is a core histone and contains a copy of the Histone (PF00125) domain at its C-terminus." [PMID:18443735, PMID:19234519, PRO:CNA]
comment: Category=family.
synonym: "H3(any)" EXACT PRO-short-label [PRO:DAN]
xref: PIRSF:PIRSF002051
is_a: PR:000000001 ! protein

[Term]
id: PR:000027595
name: fungal histone H3.3
def: "A histone H3 that is a translation product of the Schizosaccharomyces pombe 972h- hht3 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. Requested by=PomBase. This term name is preceeded by fungal to distinguish from PR:000008425.
synonym: "hht3" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027594 ! histone H3

[Term]
id: PR:000027597
name: fungal histone H3.3, initiator methionine removed form
def: "A fungal histone H3.3 that has had the initiator methionine removed." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "hht3/InitMet-" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027595 ! fungal histone H3.3

[Term]
id: PR:000027598
name: fungal histone H3.3, initiator methionine removed form (fission yeast)
def: "A fungal histone H3.3, initiator methionine removed form in Schizosaccharomyces pombe." [PMID:11242054, PMID:20929775, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-hht3/InitMet-" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027597 ! fungal histone H3.3, initiator methionine removed form

[Term]
id: PR:000027599
name: fungal histone H3.3, initiator methionine removed unphosphorylated form
def: "A fungal histone H3.3, initiator methionine removed which lacks phosphorylated residues." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "hht3/InitMet-/PhosRes-" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027597 ! fungal histone H3.3, initiator methionine removed form

[Term]
id: PR:000027600
name: fungal histone H3.3, initiator methionine removed unphosphorylated form (fission yeast)
def: "A fungal histone H3.3, initiator methionine removed unphosphorylated form in Schizosaccharomyces pombe. Example: UniProtKB:P10651-1, 2-136." [PMID:11242054, PMID:20929775, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-hht3/InitMet-/PhosRes-" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027598 ! fungal histone H3.3, initiator methionine removed form (fission yeast)
is_a: PR:000027599 ! fungal histone H3.3, initiator methionine removed unphosphorylated form

[Term]
id: PR:000027601
name: fungal histone H3.3, initiator methionine removed phosphorylated 1
def: "A fungal histone H3.3, initiator methionine removed form which has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "H3-pT3" RELATED []
synonym: "hht3/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027597 ! fungal histone H3.3, initiator methionine removed form

[Term]
id: PR:000027602
name: fungal histone H3.3, initiator methionine removed phosphorylated 1 (fission yeast)
def: "A fungal histone H3.3, initiator methionine removed phosphorylated 1 in Schizosaccharomyces pombe. Phosphorylated by Haspin. Example: UniProtKB:P10651-1, 2-136, Thr-4, MOD:00047." [PMID:20929775, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase. Note that this form is referred to as H3-pT3, because the initial methionine is not counted.
synonym: "H3-pT3" RELATED []
synonym: "Spom-hht3/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027598 ! fungal histone H3.3, initiator methionine removed form (fission yeast)
is_a: PR:000027601 ! fungal histone H3.3, initiator methionine removed phosphorylated 1

[Term]
id: PR:000027603
name: fungal histone H3.3, initiator methionine removed methylated 1
def: "A fungal histone H3.3, initiator methionine removed which has at least one methylated residue." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "hht3/InitMet-/Me:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027597 ! fungal histone H3.3, initiator methionine removed form

[Term]
id: PR:000027604
name: fungal histone H3.3, initiator methionine removed methylated 1 (fission yeast)
def: "A fungal histone H3.3, initiator methionine removed methylated 1 in Schizosaccharomyces pombe. Methylated by HP1. Example: UniProtKB:P10651-1, 2-136, Lys-10, MOD:00663." [PMID:11242054, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase. Note that in the article cited residue number is different because the initial methionine is not counted.
synonym: "Spom-hht3/InitMet-/Me:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027598 ! fungal histone H3.3, initiator methionine removed form (fission yeast)
is_a: PR:000027603 ! fungal histone H3.3, initiator methionine removed methylated 1

[Term]
id: PR:000027605
name: mediator of replication checkpoint protein 1
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- mrc1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. Requested by=PomBase.
synonym: "DNA replication checkpoint mediator mrc1" EXACT []
synonym: "mrc1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000027607
name: mediator of replication checkpoint protein 1 unmodified form
def: "A mediator of replication checkpoint protein 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "mrc1/UnMod" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027605 ! mediator of replication checkpoint protein 1

[Term]
id: PR:000027608
name: mediator of replication checkpoint protein 1 unmodified form (fission yeast)
def: "A mediator of replication checkpoint protein 1 unmodified form in Schizosaccharomyces pombe." [PMID:14585996, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-mrc1/UnMod" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027607 ! mediator of replication checkpoint protein 1 unmodified form

[Term]
id: PR:000027609
name: mediator of replication checkpoint protein 1 phosphorylated 1
def: "A mediator of replication checkpoint protein 1 phosphorylated form that has been phosphorylated at least in the third Thr or Ser residue within the [ST]Qx[ST]Qx(6-7)[ST]Q motif in the second [ST]Q cluster. Example: UniProtKB:Q9P7T4-1, Thr-645, MOD:00047." [PMID:14585996, PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "mrc1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027611 ! mediator of replication checkpoint protein 1 phosphorylated form

[Term]
id: PR:000027610
name: mediator of replication checkpoint protein 1 phosphorylated 1 (fission yeast)
def: "A mediator of replication checkpoint protein 1 phosphorylated 1 in Schizosaccharomyces pombe. Phosphorylated at least on the last Thr residue within the TQxSQx(6)TQ motif. Phosphorylated by Rad3 and Tel1. UniProtKB:Q9P7T4-1, Thr-645, MOD:00047." [PMID:14585996, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-mrc1/Phos:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027609 ! mediator of replication checkpoint protein 1 phosphorylated 1

[Term]
id: PR:000027611
name: mediator of replication checkpoint protein 1 phosphorylated form
def: "A mediator of replication checkpoint protein 1 that has been post-translationally modified to include at least one phosphorylated residue in any of the [ST]Q motifs." [PMID:14585996, PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "mrc1/PhosRes+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027605 ! mediator of replication checkpoint protein 1
is_a: PR:000037070 ! phosphoprotein

[Term]
id: PR:000027612
name: mediator of replication checkpoint protein 1 phosphorylated 2
def: "A mediator of replication checkpoint protein 1 phosphorylated form that has been phosphorylated at least in the second Ser residue within the 3S region of the first [ST]Q clusters. Example: UniProtKB:Q9P7T4-1, Ser-604, MOD:00046." [PMID:14585996, PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "mrc1/Phos:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027611 ! mediator of replication checkpoint protein 1 phosphorylated form

[Term]
id: PR:000027613
name: mediator of replication checkpoint protein 1 phosphorylated 2 (fission yeast)
def: "A mediator of replication checkpoint protein 1 phosphorylated 2 in Schizosaccharomyces pombe. Phosphorylated by Rad3 and Tel1. UniProtKB:Q9P7T4-1, Ser-604, MOD:00046." [PMID:14585996, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-mrc1/Phos:2" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027612 ! mediator of replication checkpoint protein 1 phosphorylated 2

[Term]
id: PR:000027614
name: transcription factor zip1
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- zip1 gene or a 1:1 ortholog thereof." [PMID:15660136, PRO:CNA]
comment: Category=gene. Requested by=PomBase.
synonym: "SPAC25G10.03" RELATED []
synonym: "zip1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000027616
name: transcription factor zip1 unmodified form
def: "A transcription factor zip1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "zip1/UnMod" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027614 ! transcription factor zip1

[Term]
id: PR:000027617
name: transcription factor zip1 unmodified form (fission yeast)
def: "A transcription factor zip1 unmodified form in Schizosaccharomyces pombe." [PMID:15660136, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-zip1/UnMod" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027616 ! transcription factor zip1 unmodified form

[Term]
id: PR:000027618
name: transcription factor zip1 phosphorylated form
def: "A transcription factor zip1 that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "zip1/PhosRes+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027614 ! transcription factor zip1
is_a: PR:000037070 ! phosphoprotein

[Term]
id: PR:000027619
name: transcription factor zip1 phosphorylated form (fission yeast)
def: "A transcription factor zip1 phosphorylated form in Schizosaccharomyces pombe. Example: UniProtKB:Q10424-1, MOD:00696." [PMID:15660136, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-zip1/PhosRes+" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027618 ! transcription factor zip1 phosphorylated form

[Term]
id: PR:000027620
name: transcription factor zip1 ubiquitinated form
def: "A transcription factor zip1 that has been post-translationally modified to include at least one ubiquitinated residue." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "zip1/UbiqLys+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027614 ! transcription factor zip1
is_a: PR:000037077 ! ubiquitinated protein

[Term]
id: PR:000027621
name: transcription factor zip1 ubiquitinated form (fission yeast)
def: "A transcription factor zip1 ubiquitinated form in Schizosaccharomyces pombe. Ubiquitinated by SCF(Pof1). Example: UniProtKB:Q10424-1, MOD:01148." [PMID:15660136, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-zip1/UbiqLys+" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027620 ! transcription factor zip1 ubiquitinated form

[Term]
id: PR:000027622
name: CDC14-type phosphatase
def: "A protein that contains a conserved N-terminal copy of the DSPc (PF00782) domain. This domain contains a region that might contribute to substrate specificity and a catalytic region that encompasses the PTP signature motif. The C-terminal domain length varies among different members of this class." [PMID:20720150, PRO:CNA]
comment: Category=family.
is_a: PR:000000001 ! protein

[Term]
id: PR:000027623
name: tyrosine-protein phosphatase CDC14
def: "A CDC14-type phosphatase that is a translation product of the yeast CDC14 gene or a 1:1 ortholog thereof." [PMID:16085489, PMID:18951025, PRO:CNA]
comment: Category=gene. CDC14 is called CLP1 in Schizosaccharomyces pombe.
synonym: "CDC14" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027622 ! CDC14-type phosphatase

[Term]
id: PR:000027625
name: tyrosine-protein phosphatase CDC14 unmodified form
def: "A tyrosine-protein phosphatase CDC14 homolog that has not been subjected to any co- or post-translational modification." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "CDC14/UnMod" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027623 ! tyrosine-protein phosphatase CDC14

[Term]
id: PR:000027626
name: tyrosine-protein phosphatase CDC14 unmodified form (fission yeast)
def: "A tyrosine-protein phosphatase CDC14 unmodified form in Schizosaccharomyces pombe." [PMID:16085489, PMID:18951025, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "clip1p unmodified" RELATED []
synonym: "flp1p unmodified" RELATED []
synonym: "Spom-CDC14/UnMod" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027625 ! tyrosine-protein phosphatase CDC14 unmodified form

[Term]
id: PR:000027627
name: tyrosine-protein phosphatase CDC14 phosphorylated form
def: "A tyrosine-protein phosphatase CDC14 homolog that has been modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "CDC14 phosphorylated" BROAD []
synonym: "CDC14/PhosRes+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027623 ! tyrosine-protein phosphatase CDC14
is_a: PR:000037070 ! phosphoprotein

[Term]
id: PR:000027628
name: tyrosine-protein phosphatase CDC14 phosphorylated 1
def: "A tyrosine-protein phosphatase CDC14 phosphorylated form that has been phosphorylated at the Ser residue within the RxxS motifs. Example: UniProtKB:Q9P7H1-1, Ser-396/Ser-408/Ser-467/Ser-468/Ser-493/Ser-513, MOD:00046." [PMID:16085489, PMID:18951025, PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "CDC14/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027627 ! tyrosine-protein phosphatase CDC14 phosphorylated form

[Term]
id: PR:000027629
name: tyrosine-protein phosphatase CDC14 phosphorylated 1 (fission yeast)
def: "A tyrosine-protein phosphatase CDC14 phosphorylated 1 in Schizosaccharomyces pombe. Phoshorylated in RxxS motifs by Sid2 family kinases. Example: UniProtKB:Q9P7H1-1, Ser-396/Ser-408/Ser-467/Ser-468/Ser-493/Ser-513, MOD:00046." [PMID:16085489, PMID:18951025, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "clip1p phosphorylated" RELATED []
synonym: "flp1p phosphorylated" RELATED []
synonym: "Spom-CDC14/Phos:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027628 ! tyrosine-protein phosphatase CDC14 phosphorylated 1

[Term]
id: PR:000027702
name: kinesin-like motor protein klp9/SPBC15D4.01c
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- klp9 gene or a 1:1 ortholog thereof." [PomBase:SPBC15D4.01c, PRO:CNA]
comment: Category=gene. Requested by=PomBase.
synonym: "klp9" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000027704
name: kinesin-like motor protein klp9/SPBC15D4.01c unmodified form
def: "A kinesin-like motor protein klp9/SPBC15D4.01c that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "klp9/UnMod" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027702 ! kinesin-like motor protein klp9/SPBC15D4.01c

[Term]
id: PR:000027705
name: kinesin-like motor protein klp9/SPBC15D4.01c unmodified form (fission yeast)
def: "A kinesin-like motor protein klp9/SPBC15D4.01c unmodified form in Schizosaccharomyces pombe." [PMID:18257517, PMID:19686686, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-klp9/UnMod" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027704 ! kinesin-like motor protein klp9/SPBC15D4.01c unmodified form

[Term]
id: PR:000027706
name: kinesin-like motor protein klp9/SPBC15D4.01c phosphorylated form
def: "A kinesin-like motor protein klp9/SPBC15D4.01c that has been post-translationally modified to include at least one phosphorylated residues." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "klp9/PhosRes+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027702 ! kinesin-like motor protein klp9/SPBC15D4.01c

[Term]
id: PR:000027707
name: kinesin-like motor protein klp9/SPBC15D4.01c phosphorylated 1
def: "A kinesin-like motor protein klp9/SPBC15D4.01c phosphorylated form that has been phosphorylated on one or more of the CDC2-dependent phosphorylation sites at the C-terminal region." [PMID:18257517, PMID:19686686]
comment: Category=modification. Requested by=PomBase.
synonym: "klp9/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027706 ! kinesin-like motor protein klp9/SPBC15D4.01c phosphorylated form

[Term]
id: PR:000027708
name: kinesin-like motor protein klp9/SPBC15D4.01c phosphorylated 1 (fission yeast)
def: "A kinesin-like motor protein klp9/SPBC15D4.01c phosphorylated 1 in Schizosaccharomyces pombe. Phosphorylated by cdc2p during mitosis. Example: UniProtKB:Q1MTQ7-1, Ser-605, MOD:00046, and/or (Ser-611, MOD:00046, or Ser-613, MOD:00046)." [PMID:18257517, PMID:19686686, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase. Note that there's a discrepancy between the two papers cited as to which residues are phosphorylated. The residues listed are those shown in the supplementary list of phosphopeptides in PMID:18257517. The text of PMID:19686686 reference back to PMID:18257517 but cites the incorrect residue numbers.
synonym: "Spom-klp9/Phos:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027707 ! kinesin-like motor protein klp9/SPBC15D4.01c phosphorylated 1

[Term]
id: PR:000027713
name: ribonucleoside-diphosphate reductase small chain
def: "A ribonucleoside-diphosphate reductase class I, small subunit that is a translation product of the Schizosaccharomyces pombe 972h- suc22 gene or a 1:1 ortholog thereof." [PMID:12867051, PMID:20516199, PomBase:MAH]
comment: Category=gene. Requested by=PomBase.
synonym: "Ribonucleotide reductase small subunit" BROAD []
synonym: "suc22" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027717 ! ribonucleoside-diphosphate reductase class I, small subunit

[Term]
id: PR:000027715
name: GTP-binding nuclear protein spi1
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- spi1 gene or a 1:1 ortholog thereof." [PMID:18422602, PomBase:MAH]
comment: Category=gene. Requested by=PomBase.
synonym: "SPI1" RELATED []
synonym: "spi1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000027717
name: ribonucleoside-diphosphate reductase class I, small subunit
def: "A protein that is a stand-alone version of the Ribonucleotide reductase, small chain (PF00268) domain. This protein is the small subunit of the ribonucleotide reductase complex. The active subunit binds iron and contains an active site tyrosine radical." [PMID:15158709]
comment: Category=family. Requested by=PomBase.
synonym: "Ribonucleotide reductase small subunit" BROAD []
xref: PIRSF:PIRSF000355
is_a: PR:000000001 ! protein

[Term]
id: PR:000027718
name: ribonucleoside-diphosphate reductase large chain
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- cdc22 gene or a 1:1 ortholog thereof." [PMID:14648198, PRO:CNA]
comment: Category=gene. Requested by=PomBase.
synonym: "CDC22" RELATED []
synonym: "cdc22" EXACT PRO-short-label [PRO:DNx]
synonym: "Ribonucleotide reductase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000027720
name: ribonucleoside-diphosphate reductase complex (fission yeast)
def: "A ribonucleoside-diphosphate reductase complex that is composed of two small (suc22) subunits and two large (cdc22) subunits." [PMID:20516199, PMID:8479429, PRO:CNA]
comment: Category=organism-complex. Requested by=PomBase.
synonym: "fission yeast ribonucleotide reductase complex" EXACT []
synonym: "fission yeast RNR" EXACT []

[Term]
id: PR:000027728
name: myosin type-2 heavy chain 1
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- myo2 gene or a 1:1 ortholog thereof." [PMID:15184401, PRO:CNA]
comment: Category=gene. Requested by=PomBase.
synonym: "myo2" EXACT PRO-short-label [PRO:DNx]
synonym: "Myosin type II heavy chain 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000027730
name: myosin type-2 heavy chain 1 unmodified form
def: "A myosin type-2 heavy chain 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "myo2/UnMod" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027728 ! myosin type-2 heavy chain 1

[Term]
id: PR:000027731
name: myosin type-2 heavy chain 1 unmodified form (fission yeast)
def: "A myosin type-2 heavy chain 1 unmodified form in Schizosaccharomyces pombe." [PMID:15184401, PomBase:MAH]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-myo2/UnMod" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027730 ! myosin type-2 heavy chain 1 unmodified form

[Term]
id: PR:000027732
name: myosin type-2 heavy chain 1 phosphorylated 1
def: "A myosin type-2 heavy chain 1 that has been phosphorylated on a Ser residue located in at the C-terminal region after the proline cluster. Example: UniProtKB:Q9USI6-1, Ser-1444, MOD:00046." [PMID:15184401, PomBase:MAH]
comment: Category=modification. Requested by=PomBase.
synonym: "myo2/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027728 ! myosin type-2 heavy chain 1

[Term]
id: PR:000027733
name: myosin type-2 heavy chain 1 phosphorylated 1 (fission yeast)
def: "A myosin type-2 heavy chain 1 phosphorylated 1 in Schizosaccharomyces pombe. UniProtKB:Q9USI6-1, Ser-1444, MOD:00046." [PMID:15184401, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom-myo2/Phos:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027732 ! myosin type-2 heavy chain 1 phosphorylated 1

[Term]
id: PR:000027845
name: E3 ubiquitin-protein ligase dma1
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- dma1 gene or a 1:1 ortholog thereof." [PRO:DAN]
comment: Category=gene. Requested by=PomBase.
synonym: "dma1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000000001 ! protein

[Term]
id: PR:000027897
name: AP-1-like transcription factor
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- pap1 gene or a 1:1 ortholog thereof." [PMID:15165244, PMID:1899230, PomBase:MAH]
comment: Category=gene. Requested by=PomBase.
synonym: "CAF3" RELATED []
synonym: "Caffeine resistance protein 3" EXACT []
synonym: "pap1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000027986
name: tropomyosin cdc8 (fission yeast)
def: "A tropomyosin cdc8 that is encoded in the genome of fission yeast." [PRO:DAN]
comment: Category=organism-gene.
synonym: "Spom-cdc8" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000028197 ! tropomyosin cdc8

[Term]
id: PR:000028006
name: hht3 (fission yeast)
def: "A protein coding gene hht3 in fission yeast." [PRO:DAN]
comment: Category=external.

[Term]
id: PR:000028197
name: tropomyosin cdc8
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- cdc8 gene or a 1:1 ortholog thereof." [PRO:DAN]
comment: Category=gene.
synonym: "cdc8" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000000001 ! protein

[Term]
id: PR:000028932
name: peroxiredoxin tpx1
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- tpx1 gene or a 1:1 ortholog thereof." [PMID:22245228, PRO:CNA]
comment: Category=gene. Requested by=PomBase.
synonym: "Peroxiredoxin tsa1" EXACT []
synonym: "Thioredoxin peroxidase" EXACT []
synonym: "TPX1" RELATED []
synonym: "tpx1" EXACT PRO-short-label [PRO:DNx]
synonym: "TSA1" RELATED []
is_a: PR:000000001 ! protein

[Term]
id: PR:000028933
name: peroxiredoxin tpx1 reduced form
def: "A peroxiredoxin tpx1 that its peroxidatic cysteine is in the reduced state." [PMID:22245228, PRO:CNA]
comment: Category=modification. Requested by=PomBase.
synonym: "tpx1/Red+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000028932 ! peroxiredoxin tpx1

[Term]
id: PR:000028934
name: peroxiredoxin tpx1 reduced form (fission yeast)
def: "A peroxiredoxin tpx1 reduced form in Schizosaccharomyces pombe." [PMID:22245228, PRO:CNA]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-tpx1/Red+" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000028933 ! peroxiredoxin tpx1 reduced form

[Term]
id: PR:000028935
name: peroxiredoxin tpx1 hyperoxidized form
def: "A peroxiredoxin tpx1 that its peroxidatic Cys residue is hyperoxidized." [PMID:22245228, PRO:CNA]
comment: Category=modification.
synonym: "tpx1/HyperOx+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000028932 ! peroxiredoxin tpx1

[Term]
id: PR:000028936
name: peroxiredoxin tpx1 hyperoxidized form (fission yeast)
def: "A peroxiredoxin tpx1 hyperoxidized form in Schizosaccharomyces pombe. The oxidation occurs in under oxidative stress." [PMID:22245228, PRO:CNA]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-tpx1/HyperOx+" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000028935 ! peroxiredoxin tpx1 hyperoxidized form

[Term]
id: PR:000028937
name: AP-1-like transcription factor reduced form
def: "An AP-1-like transcription factor that its Cys residues are in the reduced state (as thiols)." [PRO:CNA]
comment: Category=modification.
synonym: "pap1/Red+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027897 ! AP-1-like transcription factor

[Term]
id: PR:000028938
name: AP-1-like transcription factor reduced form (fission yeast)
def: "An AP-1-like transcription factor reduced form in Schizosaccharomyces pombe." [PMID:22245228, PRO:CNA]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-pap1/Red+" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000028937 ! AP-1-like transcription factor reduced form

[Term]
id: PR:000028939
name: AP-1-like transcription factor oxidized form
def: "An AP-1-like transcription factor that regulatory Cys residues are in the oxidized state (forming disulfide bonds)." [PMID:22245228, PRO:CNA]
comment: Category=modification.
synonym: "pap1/Ox+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027897 ! AP-1-like transcription factor

[Term]
id: PR:000028940
name: AP-1-like transcription factor oxidized form (fission yeast)
def: "An AP-1-like transcription factor oxidized form in Schizosaccharomyces pombe. This form is produced under oxidative stress." [PMID:22245228, PRO:CNA]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-pap1/Ox+" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000028939 ! AP-1-like transcription factor oxidized form

[Term]
id: PR:000028942
name: peptide methionine sulfoxide reductase reduced form
def: "A probable peptide methionine sulfoxide reductase that its regulatory Cys residues are in the reduced state." [PRO:CNA]
comment: Category=modification.
synonym: "MSRA/Red+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000010680 ! peptide methionine sulfoxide reductase

[Term]
id: PR:000028943
name: peptide methionine sulfoxide reductase reduced form (fission yeast)
def: "A peptide methionine sulfoxide reductase reduced form that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:22245228, PRO:CNA]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-MSRA/Red+" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000028942 ! peptide methionine sulfoxide reductase reduced form

[Term]
id: PR:000028944
name: peptide methionine sulfoxide reductase oxidized form
def: "A peptide methionine sulfoxide reductase that regulatory Cys residues are in the oxidized state." [PMID:22245228, PRO:CNA]
comment: Category=modification.
synonym: "MSRA/Ox+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000010680 ! peptide methionine sulfoxide reductase

[Term]
id: PR:000028945
name: peptide methionine sulfoxide reductase oxidized form (fission yeast)
def: "A peptide methionine sulfoxide reductase oxidized form in Schizosaccharomyces pombe." [PMID:22245228, PRO:CNA]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-MSRA/Ox+" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000028944 ! peptide methionine sulfoxide reductase oxidized form

[Term]
id: PR:000028946
name: thioredoxin reduced form
def: "A thioredoxin that the Cys residues involved in dithiol-disulfide activity (CxxC motif) are in the reduced state." [PMID:22245228, PRO:CNA]
comment: Category=modification.
synonym: "Trx1-(SH)2" RELATED []
synonym: "TXN/Red+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000016853 ! thioredoxin

[Term]
id: PR:000028947
name: thioredoxin-1 reduced form (fission yeast)
def: "A thioredoxin reduced form in Schizosaccharomyces pombe. The reduced Cys are Cys-30 and Cys-33 in UniProtKB:O14463." [PMID:22245228, PRO:CNA]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-TXN/Red+" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000028946 ! thioredoxin reduced form

[Term]
id: PR:000028948
name: thioredoxin oxidized form
def: "A thioredoxin that the Cys residues involved in dithiol-disulfide activity (CxxC motif) are forming disulfide bond." [PMID:22245228, PRO:CNA]
comment: Category=modification.
synonym: "Trx1-S2" RELATED []
synonym: "TXN/Ox+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000016853 ! thioredoxin

[Term]
id: PR:000028949
name: thioredoxin-1 oxidized form (fission yeast)
def: "A thioredoxin oxidized form in Schizosaccharomyces pombe. The disulfide bond involves Cys-30 and Cys-33 in UniProtKB:O14463." [PMID:22245228, PRO:CNA]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-TXN/Ox+" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000028948 ! thioredoxin oxidized form

[Term]
id: PR:000028950
name: peroxiredoxin tpx1 complex
def: "A protein complex that its a dimer of peroxiredoxin tpx1 linked by an interchain disulfide bond." [PMID:22245228, PRO:CNA]
comment: Category=complex. Requested by=PomBase.

[Term]
id: PR:000028951
name: peroxiredoxin tpx1 complex (fission yeast)
def: "A peroxiredoxin tpx1 complex in Schizosaccharomyces pombe." [PMID:22245228, PRO:CNA]
comment: Category=organism-complex. Requested by=PomBase.
is_a: PR:000028950 ! peroxiredoxin tpx1 complex

[Term]
id: PR:000028988
name: sterol regulatory element-binding protein
def: "A protein that is a transmembrane protein where both N- and C-terminus are cytosolic, and the N-terminus contains a basic helix-loop-helix domain (PF00010) and functions as a transcription factor when cleaved off." [PMID:17303406]
comment: Category=family.
synonym: "bHLHd1" BROAD []
synonym: "class D basic helix-loop-helix protein 1" BROAD []
synonym: "SRE" RELATED []
synonym: "SREBF" RELATED []
synonym: "SREBP" RELATED []
synonym: "sterol regulatory element-binding transcription factor" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000028989
name: sre1-type sterol regulatory element-binding protein 1
def: "A sterol regulatory element-binding protein that is a translation product of the Schizosaccharomyces pombe 972h- sre1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "SRE-1" RELATED []
synonym: "SRE1" RELATED []
synonym: "sre1" EXACT PRO-short-label [PRO:DNx]
synonym: "SREBP1" RELATED []
is_a: PR:000028988 ! sterol regulatory element-binding protein

[Term]
id: PR:000028990
name: sre1-type sterol regulatory element-binding protein 1 proteolytic cleavage product
def: "A proteolytic cleavage product that is derived from sre1-type sterol regulatory element-binding protein 1." [PRO:CNA]
comment: Category=modification.
synonym: "sre1/ClvPrd" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000018264 ! proteolytic cleavage product

[Term]
id: PR:000028991
name: sre1-type sterol regulatory element-binding protein 1 cleaved 1
def: "A sre1-type sterol regulatory element-binding protein 1 that has been processed by proteolytic cleavage yielding the N-terminal domain. Example: UniProtKB:Q9UUD1-1, 1-440." [PMID:22017871, PRO:CNA]
comment: Category=modification.
synonym: "Processed sterol regulatory element-binding protein 1" RELATED []
synonym: "sre1/Clv:1" EXACT PRO-short-label [PRO:DAN]
synonym: "Sre1N" RELATED []
is_a: PR:000028990 ! sre1-type sterol regulatory element-binding protein 1 proteolytic cleavage product

[Term]
id: PR:000028992
name: Sre1N (fission yeast)
def: "A sre1-type sterol regulatory element-binding protein 1 cleaved 1 in Schizosaccharomyces pombe. This form is the N-terminal domain of the membrane protein sre1 that is cleaved off upon activation (e.g. by hypoxia). UniProtKB:Q9UUD1-1, 1-440." [PMID:22017871, PomBase:AL]
comment: Category=organism-modification. Requested by=PomBase.
is_a: PR:000028991 ! sre1-type sterol regulatory element-binding protein 1 cleaved 1

[Term]
id: PR:000029043
name: Schizosaccharomyces pombe 972h- protein
def: "A protein that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:DAN]
synonym: "Spom972h- protein" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000000001 ! protein

[Term]
id: PR:000029190
name: cyclin B:Cdk1 complex
def: "A cyclin-dependent protein kinase holoenzyme complex that has a cyclin B regulatory subunit and a Cdk1 kinase subunit." [PRO:CNA]
comment: Category=complex.
synonym: "cyclin B:Cdc2 complex" EXACT []

[Term]
id: PR:000029191
name: cell cycle-related cyclin
def: "A protein that consists of a copy of the Cyclin, N-terminal domain (PF00134) and a copy of the Cyclin, C-terminal domain (PF02984). This class includes the G1/S cyclins, essential for the control of the cell cycle at the G1/S transition, and the G2/M cyclins, essential for the control of the cell cycle at the G2/M transition." [PRO:CNA, Wikipedia:Cyclin]
comment: Category=family.
synonym: "cyclin, A/B/D/E types" EXACT [PIRSF:PIRSF001771]
xref: PIRSF:PIRSF001771
is_a: PR:000000001 ! protein

[Term]
id: PR:000029192
name: G2/mitotic-specific cyclin-B
def: "A cell cycle-related cyclin that is a translation product of either human CCNB1, CCNB2, or CCNB3 gene or their corresponding 1:1 ortholog thereof." [PRO:CNA, Wikipedia:Cyclin]
comment: Category=family.
synonym: "cyclin B" EXACT []
is_a: PR:000029191 ! cell cycle-related cyclin

[Term]
id: PR:000029916
name: mitotic checkpoint serine/threonine-protein kinase BUB1 unphosphorylated form
def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 which lacks phosphorylated residues." [PRO:CNA]
comment: Category=modification.
synonym: "BUB1/PhosRes-" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000004854 ! mitotic checkpoint serine/threonine-protein kinase BUB1

[Term]
id: PR:000035410
name: mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 5 (Schizosaccharomyces pombe 972h-)
def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 5 in Schizosaccharomyces pombe 972h- that represents the basal phosphorylated state observed during interphase and mitosis. UniProtKB:O94751, MOD:00696." [PMID:12606573, PRO:KER]
comment: Category=organism-modification.
synonym: "Spom972h-BUB1/Phos:5" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000035691 ! mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 5
is_a: PR:O94751 ! mitotic checkpoint serine/threonine-protein kinase BUB1 (Schizosaccharomyces pombe 972h-)

[Term]
id: PR:000035411
name: mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 6 (Schizosaccharomyces pombe 972h-)
def: "A BUB1 CDK-consensus sites phosphorylated form in Schizosaccharomyces pombe 972h-. The exact combination of phosphorylated sites is not known but may involved Thr-340, Thr-423, Thr-455, and/or Ser-466 in UniProtKB:O94751. Phosphorylation occurs during Meiosis I or spindle disruption (tubulin mutant). UniProtKB:O94751, Thr-340/Thr-423/Thr-455, MOD:00047|Ser-466, MOD:00046." [PMID:12606573, PRO:KER]
comment: Category=organism-modification. Kinase=("CDC2"; PR:P04551).
is_a: PR:000035413 ! BUB1 CDK-consensus sites phosphorylated form
is_a: PR:O94751 ! mitotic checkpoint serine/threonine-protein kinase BUB1 (Schizosaccharomyces pombe 972h-)

[Term]
id: PR:000035413
name: BUB1 CDK-consensus sites phosphorylated form
def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 that is phosphorylated on CDK consensus sites (S/T-P-X-K/R) located in the middle region of BUB1." [PMID:12606573, PMID:16760428, PRO:KER]
comment: Category=modification.
synonym: "BUB1/PhosRes+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000004854 ! mitotic checkpoint serine/threonine-protein kinase BUB1

[Term]
id: PR:000035414
name: mitotic checkpoint serine/threonine-protein kinase BUB1 unphosphorylated form (Schizosaccharomyces pombe 972h-)
def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 unphosphorylated form in Schizosaccharomyces pombe 972h-." [PRO:CNA]
comment: Category=organism-modification.
synonym: "Spom972h-BUB1/PhosRes-" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000029916 ! mitotic checkpoint serine/threonine-protein kinase BUB1 unphosphorylated form
is_a: PR:O94751 ! mitotic checkpoint serine/threonine-protein kinase BUB1 (Schizosaccharomyces pombe 972h-)

[Term]
id: PR:000035499
name: spindle assembly checkpoint component MAD3
def: "A protein that is a translation product of the Saccharomyces cerevisiae MAD3 gene or a 1:1 ortholog thereof. MAD3 is related to BUB1 and BUB1B, all of which contain the Mad3/BUB1 homology region 1 (PF00831), but MAD3 lacks the C-terminal Protein kinase domain (PF00069)." [PMID:15970700, PMID:22698286, PRO:KER]
comment: Category=gene.
synonym: "MAD3" EXACT PRO-short-label [PRO:DNx]
synonym: "Mitotic MAD3 protein" BROAD []
is_a: PR:000000001 ! protein

[Term]
id: PR:000035544
name: histone H2A-alpha phosphorylated 2 (human)
def: "A histone H2A.1 phosphorylated 2 in human. UniProtKB:P0C0S8-1, Thr-121, MOD:00047." [PMID:19965387, PRO:KER]
comment: Category=organism-modification. Kinase=("BUB1"; PR:O43683).
synonym: "hhta1/Phos:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027565 ! histone H2A-alpha phosphorylated 2

[Term]
id: PR:000035566
name: BUB1:BUB3 complex
def: "A protein complex that is composed of BUB1 and BUB3. This complex is involved in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated." [PMID:10198256, PMID:11283619, PMID:15525512, PRO:KER]
comment: Category=complex.

[Term]
id: PR:000035569
name: BUB1:BUB3 complex (Schizosaccharomyces pombe 972h-)
def: "A BUB1:BUB3 complex whose components are encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:22660415, PRO:KER]
comment: Category=organism-complex.
synonym: "BUB1:BUB3 complex" RELATED []
is_a: PR:000035566 ! BUB1:BUB3 complex

[Term]
id: PR:000035574
name: MAD2:MAD3 complex (Schizosaccharomyces pombe 972h-)
def: "A MAD2:MAD3 complex whose components are encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:12676091, PRO:KER]
comment: Category=organism-complex.
synonym: "MAD2:MAD3 complex" RELATED []

[Term]
id: PR:000035665
name: BUB1/BUB1B protein
def: "A protein that consists of a core domain composition consisting of a the Mad3/BUB1 homology region 1 (PF00831) and a C-terminal Protein kinase domain (PF00069). Members of this class are related to MAD3." [PMID:22698286, PRO:CNA]
comment: Category=family.
is_a: PR:000000001 ! protein

[Term]
id: PR:000035691
name: mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 5
def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "BUB1 phosphorylated" RELATED []
synonym: "BUB1/Phos:5" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000004854 ! mitotic checkpoint serine/threonine-protein kinase BUB1

[Term]
id: PR:000035694
name: histone H2A-alpha unmodified form (human)
def: "A histone H2A-alpha unmodified form in human." [PRO:KER]
comment: Category=organism-modification.
synonym: "hhta1/UnMod" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027560 ! histone H2A-alpha unmodified form

[Term]
id: PR:000036264
name: histone H3.1 acetylated 1 (human)
def: "A histone H3.1 that is N-terminal Met acetylated in human. UniProtKB:P68431-1, Met-1, MOD:00058." [TDR:PFR1490]
comment: Category=organism-modification. Note=Top down proteomics.
synonym: "hhht1/Ac:1" EXACT PRO-short-label [PRO:DNx]
xref: TDR:PFR1490
is_a: PR:000027569 ! histone H3.1

[Term]
id: PR:000037070
name: phosphoprotein
def: "A protein that contains at least one phosphorylated residue." [PRO:DAN]
comment: Category=modification.
synonym: "phosphorylated protein" EXACT [PRO:DAN]
synonym: "Prot/PhosRes+" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000000001 ! protein

[Term]
id: PR:000037077
name: ubiquitinated protein
def: "A protein that contains at least one ubiquitinylated lysine." [PRO:DAN]
comment: Category=modification.
synonym: "Prot/UbiqLys+" EXACT PRO-short-label [PRO:DAN]
synonym: "ubiquitinylated protein" EXACT [PRO:DAN]
is_a: PR:000000001 ! protein

[Term]
id: PR:000037081
name: tropomyosin cdc8, acetylated form (fission yeast)
def: "A tropomyosin cdc8 (fission yeast) that has been post-translationally modified to include an acetylated N-terminal methionine." [PRO:DAN]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-cdc8/AcRes+" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027986 ! tropomyosin cdc8 (fission yeast)

[Term]
id: PR:000037082
name: tropomyosin cdc8, non-acetylated form (fission yeast)
def: "A tropomyosin cdc8 (fission yeast) that has not been post-translationally modified to include an acetylated N-terminal methionine." [PRO:DAN]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-cdc8/AcRes-" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027986 ! tropomyosin cdc8 (fission yeast)

[Term]
id: PR:000037083
name: tropomyosin cdc8 homodimer (fission yeast)
def: "A protein complex composed of two subunits of fission yeast tropomyosin cdc8." [PRO:DAN]
comment: Category=organism-complex. Requested by=PomBase.
synonym: "Spom-(cdc8)*2" EXACT PRO-short-label [PRO:DAN]

[Term]
id: PR:000037084
name: tropomyosin cdc8 homodimer, acetylated form (fission yeast)
def: "A tropomyosin cdc8 homodimer that is compose of two subunits of the acetylated form of fission yeast tropomyosin cdc8." [PRO:DAN]
comment: Category=organism-complex. Requested by=PomBase.
synonym: "Spom-(cdc8/AcRes+)*2" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000037083 ! tropomyosin cdc8 homodimer (fission yeast)

[Term]
id: PR:000037085
name: tropomyosin cdc8 homodimer, non-acetylated form (fission yeast)
def: "A tropomyosin cdc8 homodimer that is compose of two subunits of the non-acetylated form of fission yeast tropomyosin cdc8." [PRO:DAN]
comment: Category=organism-complex. Requested by=PomBase.
synonym: "Spom-(cdc8/AcRes-)*2" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000037083 ! tropomyosin cdc8 homodimer (fission yeast)

[Term]
id: PR:000037296
name: serine/threonine-protein kinase cds1 phosphorylated 1 (fission yeast)
def: "A serine/threonine-protein kinase cds1 in fission yeast that has been phosphorylated on the Thr residue in the second TQ motif by rad3. Example: UniProtKB:Q09170, Thr-11, MOD:00047." [PMID:15173168, PomBase:AL]
comment: Category=organism-modification. Kinase=("rad3"; PR:Q02099).
is_a: PR:Q09170 ! serine/threonine-protein kinase cds1 (Schizosaccharomyces pombe 972h-)

[Term]
id: PR:000037297
name: serine/threonine-protein kinase cds1 phosphorylated 2 (fission yeast)
def: "A serine/threonine-protein kinase cds1 in fission yeast that has been phosphorylated on the Thr residue in the second TQ motif by rad3, and further phosphorylated a second Thr within the activation loop by autocatalysis. Example: UniProtKB:Q09170, Thr-11/Thr-328, MOD:00047." [PMID:19357077, PomBase:AL]
comment: Category=organism-modification. Kinase=("rad3"; PR:Q02099). Kinase=("cds1"; PR:Q09170).
synonym: "cds1 T328-P" RELATED []
is_a: PR:Q09170 ! serine/threonine-protein kinase cds1 (Schizosaccharomyces pombe 972h-)

[Term]
id: PR:000037299
name: serine/threonine-protein kinase cds1 homodimer, phosphorylated 1 (fission yeast)
def: "A protein complex composed of two subunits of fission yeast serine/threonine-protein kinase cds1 primed by rad3-rad26 complex." [PMID:19357077]
comment: Category=organism-complex.

[Term]
id: PR:000037300
name: serine/threonine-protein kinase cds1 homodimer, phosphorylated 2 (fission yeast)
def: "A protein complex composed of two subunits of fission yeast serine/threonine-protein kinase cds1 primed by rad3-rad26 complex and activated by autophosphorylation." [PMID:19357077]
comment: Category=organism-complex.

[Term]
id: PR:000037316
name: DNA repair protein rhp9 phosphorylated 1 (fission yeast)
def: "A DNA repair protein rhp9 that is phosphorylated in two Thr residues within CDK consensus TP motifs, and a Thr within the sequence VPETV. Example: UniProtKB:P87074-1, Thr-187, MOD:00047|Thr-215, MOD:00047|Thr-235, MOD:00047." [PMID:24074952, PomBase:AL]
comment: Category=organism-modification. Kinase=("cdc2"; PR:P04551). Requested by=PomBase.
synonym: "Crb2 phosphorylated" RELATED []
is_a: PR:000037070 ! phosphoprotein
is_a: PR:P87074 ! DNA repair protein rhp9 (Schizosaccharomyces pombe 972h-)

[Term]
id: PR:000037317
name: Crb2 dimer (fission yeast)
def: "A protein complex that is composed of a dimer of phosphorylated Crb2." [PMID:24074952, PomBase:AL]
comment: Category=organism-complex. Requested by=PomBase.
synonym: "DNA repair protein rhp9 dimer" EXACT []

[Term]
id: PR:000037318
name: cdc13:cdk1 complex (fission yeast)
def: "A cyclin B:Cdk1 complex that is composed of a cdc13 and cdk1 in Schizosaccharomyces pombe." [PMID:2665944, PomBase:AL]
comment: Category=organism-complex. Requested by=PomBase.
synonym: "p34cdc2:p56cdc13" RELATED []
is_a: PR:000029190 ! cyclin B:Cdk1 complex

[Term]
id: PR:O14216
name: DNA replication regulator sld2 (Schizosaccharomyces pombe 972h-)
alt_id: PR:000027524
def: "A DNA replication regulator sld2 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:11937031, PomBase:MAH]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "DNA replication regulator drc1" EXACT []
synonym: "SPAC6B12.11" RELATED []
synonym: "Spom972h-SLD2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14216
is_a: PR:000027523 ! DNA replication regulator sld2
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:O14417
name: mitotic spindle assembly checkpoint protein MAD2 (Schizosaccharomyces pombe 972h-)
alt_id: PR:000035572
def: "A mitotic spindle assembly checkpoint protein MAD2A that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:KER]
comment: Category=organism-gene.
synonym: "Spom972h-MAD2L1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14417
is_a: PR:000010038 ! mitotic spindle assembly checkpoint protein MAD2A
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:O42860
name: mitotic checkpoint protein BUB3 (Schizosaccharomyces pombe 972h-)
alt_id: PR:000035571
def: "A mitotic checkpoint protein BUB3 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:KER]
comment: Category=organism-gene.
synonym: "SPAC23H3.08c" RELATED []
synonym: "Spom972h-BUB3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O42860
is_a: PR:000004856 ! mitotic checkpoint protein BUB3
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:O59767
name: spindle assembly checkpoint component MAD3 (Schizosaccharomyces pombe 972h-)
alt_id: PR:000035573
def: "A spindle assembly checkpoint component MAD3 encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:11909965, PRO:KER]
comment: Category=organism-gene.
synonym: "mitotic spindle checkpoint component mad3" EXACT []
synonym: "SPCC1795.01C" RELATED []
synonym: "SPCC895.02" RELATED []
synonym: "Spom972h-MAD3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O59767
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein
is_a: PR:000035499 ! spindle assembly checkpoint component MAD3

[Term]
id: PR:O74887
name: peroxiredoxin tpx1 (Schizosaccharomyces pombe 972h-)
def: "A peroxiredoxin tpx1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:CNA, UniProtKB:O74887]
comment: Category=organism-gene.
synonym: "Spom972h-tpx1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O74887
is_a: PR:000028932 ! peroxiredoxin tpx1
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:O94751
name: mitotic checkpoint serine/threonine-protein kinase BUB1 (Schizosaccharomyces pombe 972h-)
alt_id: PR:000035570
def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:CNA]
comment: Category=organism-gene.
synonym: "BUB1 (pombe)" EXACT []
synonym: "SPCC1322.12c" RELATED []
synonym: "Spom972h-BUB1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O94751
is_a: PR:000004854 ! mitotic checkpoint serine/threonine-protein kinase BUB1
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:P04909
name: histone H2A-alpha (Schizosaccharomyces pombe 972h-)
alt_id: PR:000027559
def: "A histone H2A.1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:15226425, PMID:19965387, PMID:21516229, PomBase:MAH]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "SPCC622.08C" RELATED []
synonym: "Spom972h-hta1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P04909
is_a: PR:000027558 ! histone H2A-alpha
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:P04910
name: histone H2A-beta (Schizosaccharomyces pombe 972h-)
alt_id: PR:000027546
def: "A histone H2A.2 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:15226425, PMID:19965387, PMID:21516229, PomBase:MAH]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "SPAC19G12.06C" RELATED []
synonym: "Spom972h-HTA2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P04910
is_a: PR:000027545 ! histone H2A.2
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:P04912
name: histone H2A.2 (yeast)
alt_id: PR:000027555
def: "A histone H2A.2 that is encoded in the genome of yeast." [PRO:CNA]
comment: Category=organism-gene.
synonym: "YBL003C" RELATED []
synonym: "YBL0103" RELATED []
synonym: "yHTA2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P04912
is_a: PR:000027545 ! histone H2A.2

[Term]
id: PR:P06652
name: M-phase inducer phosphatase (Schizosaccharomyces pombe 972h-)
alt_id: PR:000027507
def: "An M-phase inducer phosphatase that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:9774107, PomBase:MAH]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "SPAC24H6.05" RELATED []
synonym: "Spom972h-cdc25" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P06652
is_a: PR:000027506 ! M-phase inducer phosphatase
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:P08965
name: meiosis protein mei2 (Schizosaccharomyces pombe 972h-)
alt_id: PR:000027568
def: "A meiosis protein mei2 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:9062192, PomBase:MAH]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "SPAC27D7.03C" RELATED []
synonym: "Spom972h-mei2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P08965
is_a: PR:000027567 ! meiosis protein mei2
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:P10651
name: fungal histone H3.3 (Schizosaccharomyces pombe 972h-)
alt_id: PR:000027596
def: "A fungal histone H3.3 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:11242054, PMID:20929775, PomBase:MAH]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "Spom972h-hht3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10651
is_a: PR:000027595 ! fungal histone H3.3
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:P28748
name: GTP-binding nuclear protein spi1 (Schizosaccharomyces pombe 972h-)
alt_id: PR:000027716
def: "A GTP-binding nuclear protein spi1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:18422602, PomBase:MAH]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "SPBC1289.03C" RELATED []
synonym: "Spom972h-spi1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P28748
is_a: PR:000027715 ! GTP-binding nuclear protein spi1
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:P34068
name: M-factor precursor mfm1 (Schizosaccharomyces pombe 972h-)
def: "An M-factor precursor mfm1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:MSY, UniProtKB:P34068]
comment: Category=organism-gene.
synonym: "Spom972h-mfm1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P34068
is_a: PR:000025003 ! M-factor precursor mfm1
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:P36602
name: ribonucleoside-diphosphate reductase large chain (Schizosaccharomyces pombe 972h-)
alt_id: PR:000027719
def: "A ribonucleoside-diphosphate reductase large chain that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:14648198, PRO:CNA]
comment: Category=organism-gene.
synonym: "Spom972h-cdc22" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P36602
is_a: PR:000027718 ! ribonucleoside-diphosphate reductase large chain
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:P36603
name: ribonucleoside-diphosphate reductase small chain (Schizosaccharomyces pombe 972h-)
alt_id: PR:000027714
def: "A ribonucleoside-diphosphate reductase small chain that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:12867051, PMID:20516199, PomBase:MAH]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "SPBC25D12.04" RELATED []
synonym: "Spom972h-suc22" EXACT PRO-short-label [PRO:DNx]
synonym: "SUC22" RELATED []
xref: UniProtKB:P36603
is_a: PR:000027713 ! ribonucleoside-diphosphate reductase small chain
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:P36631
name: transcription factor ste11 (Schizosaccharomyces pombe 972h-)
alt_id: PR:000027539
def: "A transcription factor ste11 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:11702950, PomBase:MAH]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "SPBC32C12.02" RELATED []
synonym: "Spom972h-ste11" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P36631
is_a: PR:000027538 ! transcription factor ste11
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:P87074
name: DNA repair protein rhp9 (Schizosaccharomyces pombe 972h-)
def: "A tumor suppressor p53-binding protein 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:DNx]
comment: Category=organism-gene.
synonym: "Spom972h-TP53BP1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P87074
is_a: PR:000016558 ! tumor suppressor p53-binding protein 1
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:Q01663
name: AP-1-like transcription factor (Schizosaccharomyces pombe 972h-)
alt_id: PR:000027898
def: "An AP-1-like transcription factor that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:15165244, PMID:1899230, PomBase:MAH]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "SPAC1783.07C" RELATED []
synonym: "Spom972h-pap1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q01663
is_a: PR:000027897 ! AP-1-like transcription factor
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:Q02088
name: tropomyosin cdc8 (Schizosaccharomyces pombe 972h-)
def: "A protein that is a translation product of the Schizosaccharomyces pombe 972h- cdc8 gene." [PRO:DNx]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "Spom972h-cdc8" EXACT PRO-short-label [PRO:DAN]
xref: UniProtKB:Q02088
is_a: PR:000028197 ! tropomyosin cdc8
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:Q09170
name: serine/threonine-protein kinase cds1 (Schizosaccharomyces pombe 972h-)
def: "A serine/threonine-protein kinase Chk2 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:DNx]
comment: Category=organism-gene.
synonym: "Spom972h-CHEK2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q09170
is_a: PR:000005418 ! serine/threonine-protein kinase Chk2
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:Q09180
name: pro-P-factor (Schizosaccharomyces pombe 972h-)
def: "A P-factor precursor that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:MSY, UniProtKB:Q09180]
comment: Category=organism-gene.
synonym: "Spom972h-map2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q09180
is_a: PR:000024854 ! P-factor precursor
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:Q09838
name: transcriptional regulator prz1 (Schizosaccharomyces pombe 972h-)
alt_id: PR:000027514
def: "A transcriptional regulator prz1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:12637524, PomBase:MAH]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "SPAC4G8.13C" RELATED []
synonym: "Spom972h-prz1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q09838
is_a: PR:000027513 ! transcriptional regulator prz1
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:Q09892
name: mitogen-activated protein kinase sty1 (Schizosaccharomyces pombe 972h-)
alt_id: PR:000027500
def: "A mitogen-activated protein kinase HOG1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:7501024, PomBase:MAH]
comment: Category=organism-gene. Requested by=PomBase. HOG1 in S. pombe is named sty1.
synonym: "HOG1" RELATED []
synonym: "PHH1" RELATED []
synonym: "SPAC24B11.06C" RELATED []
synonym: "SPC1" RELATED []
synonym: "Spom972h-HOG1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q09892
is_a: PR:000027499 ! mitogen-activated protein kinase HOG1
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:Q10322
name: E3 ubiquitin-protein ligase dma1 (Schizosaccharomyces pombe 972h-)
def: "An E3 ubiquitin-protein ligase dma1 that is a translation product of the Schizosaccharomyces pombe 972h- dma1 gene." [PRO:DNx]
comment: Category=organism-gene.
synonym: "Spom972h-dma1" EXACT PRO-short-label [PRO:DAN]
xref: UniProtKB:Q10322
is_a: PR:000027845 ! E3 ubiquitin-protein ligase dma1
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:Q10424
name: transcription factor zip1 (Schizosaccharomyces pombe 972h-)
alt_id: PR:000027615
def: "A transcription factor zip1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:15660136, PRO:CNA]
comment: Category=organism-gene.
synonym: "SPAC25G10.03" RELATED []
synonym: "Spom972h-zip1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q10424
is_a: PR:000027614 ! transcription factor zip1
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:Q1MTQ7
name: kinesin-like motor protein klp9/SPBC15D4.01c (Schizosaccharomyces pombe 972h-)
alt_id: PR:000027703
def: "A kinesin-like motor protein klp9/SPBC15D4.01c that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PomBase:SPBC15D4.01c, PRO:CNA]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "klp9p" EXACT []
synonym: "Spom972h-klp9" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q1MTQ7
is_a: PR:000027702 ! kinesin-like motor protein klp9/SPBC15D4.01c
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:Q99459
name: cell division cycle 5-like protein (human)
def: "A cell division cycle 5-like protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99459]
comment: Category=organism-gene.
synonym: "hCDC5L" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99459
is_a: PR:000005216 ! cell division cycle 5-like protein

[Term]
id: PR:Q9HDY1
name: anaphase spindle elongation protein 1 (Schizosaccharomyces pombe 972h-)
alt_id: PR:000027518
def: "An anaphase spindle elongation protein 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:19686686, PomBase:MAH]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "SPAPB1A10.09" RELATED []
synonym: "Spom972h-ase1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9HDY1
is_a: PR:000027517 ! anaphase spindle elongation protein 1
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:Q9P7H1
name: tyrosine-protein phosphatase CDC14 (Schizosaccharomyces pombe 972h-)
alt_id: PR:000027624
def: "A tyrosine-protein phosphatase CDC14 in Schizosaccharomyces pombe 972h-." [PMID:11683392, PomBase:MAH]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "CDC fourteen-like phosphatase 1" EXACT []
synonym: "CLP1" RELATED []
synonym: "FLP1" RELATED []
synonym: "SPAC1782.09C" RELATED []
synonym: "Spom972h-CDC14" EXACT PRO-short-label [PRO:DNx]
synonym: "tyrosine-protein phosphatase CDC14 homolog" EXACT []
xref: UniProtKB:Q9P7H1
is_a: PR:000027623 ! tyrosine-protein phosphatase CDC14
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:Q9P7T4
name: mediator of replication checkpoint protein 1 (Schizosaccharomyces pombe 972h-)
alt_id: PR:000027606
def: "A mediator of replication checkpoint protein 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:14585996, PomBase:MAH]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "SPAC694.06C" RELATED []
synonym: "Spom972h-mrc1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9P7T4
is_a: PR:000027605 ! mediator of replication checkpoint protein 1
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:Q9USI6
name: myosin type-2 heavy chain 1 (Schizosaccharomyces pombe 972h-)
alt_id: PR:000027729
def: "A myosin type-2 heavy chain 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PMID:15184401, PRO:CNA]
comment: Category=organism-gene.
synonym: "SPCC645.05C" RELATED []
synonym: "Spom972h-myo2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9USI6
is_a: PR:000027728 ! myosin type-2 heavy chain 1
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Term]
id: PR:Q9UUD1
name: sterol regulatory element-binding protein 1 (Schizosaccharomyces pombe 972h-)
def: "A sre1-type sterol regulatory element-binding protein 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:CNA, UniProtKB:Q9UUD1]
comment: Category=organism-gene.
synonym: "Spom972h-sre1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9UUD1
is_a: PR:000028989 ! sre1-type sterol regulatory element-binding protein 1
is_a: PR:000029043 ! Schizosaccharomyces pombe 972h- protein

[Typedef]
id: derives_from
name: derives_from
is_transitive: true

[Typedef]
id: has_component
name: has_component

[Typedef]
id: has_gene_template
name: has_gene_template

[Typedef]
id: has_modification
name: has_modification
is_transitive: true
is_obsolete: true

[Typedef]
id: has_part
name: has_part
is_transitive: true

[Typedef]
id: has_quality
name: has_quality
comment: The relationship between a feature and an attribute.

[Typedef]
id: lacks_modification
name: lacks_modification
is_transitive: true
is_obsolete: true

[Typedef]
id: lacks_part
name: lacks_part

[Typedef]
id: located_in
name: located_in
is_transitive: true

[Typedef]
id: only_in_taxon
name: only_in_taxon
def: "U only_in_taxon T: U is a feature found in only in organisms of species of taxon T. The feature cannot be found in an organism of any species outside of (not subsumed by) that taxon. Down-propagates in U hierarchy, up-propagates in T hierarchy (species taxonomy). Implies applicable_to_taxon." [ROC:Waclaw]
comment: Down-propagates. The original name for this in the paper is 'specific_to'. Applicable to genes because some genes are lost in sub-species (strains) of a species.
synonym: "never_outside_taxon" EXACT []
synonym: "specific_to" EXACT []
synonym: "specific_to_taxon" EXACT []

[Typedef]
id: part_of
name: part_of
is_transitive: true