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Last updated: 2025-03-13
429297 annotations
4738 curated publications
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Genotype:
gef1+[Overexpression]
Gene
Product
Allele name
Description
Type
Expression
gef1
RhoGEF for Cdc42 (Gef1)
gef1+
wild type
wild_type
Overexpression
Genotype summary
Single locus phenotype
Literature
Single locus phenotype
Cell
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Abnormal biological process
Abnormal catalytic activity
Abnormal cell morphology
Abnormal molecular function
Abnormal phenotype
Cell cycle phenotype
Cell population viability
Cell viability
Localization phenotype
Normal phenotype
Protein-protein interaction
Sensitive to chemical
Vegetative cell phenotype
+
spheroid vegetative cell
+
stubby vegetative cell
Literature
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Details
Year
Gef1p and Scd1p, the Two GDP-GTP exchange factors for Cdc42p, form a ring structure that shrinks during cytokinesis in Schizosaccharomyces pombe.
Hirota K et al.
Mol Biol Cell
2003 Sep;14(9):3617-27
PMID:12972551
details ...
2003
The conserved NDR kinase Orb6 controls polarized cell growth by spatial regulation of the small GTPase Cdc42.
Das M et al.
Curr Biol
2009 Aug 11;19(15):1314-9
PMID:19646873
details ...
2009
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