format-version: 1.2
data-version: 35.0.
date: 14:06:2013 15:59
saved-by: midori
auto-generated-by: OBO-Edit 2.3-beta5
synonymtypedef: PRO-common-name "Label appended to organism-specific terms in place of scientific name" EXACT
synonymtypedef: PRO-short-label "Unique short label for PRO terms for display purposes" EXACT
synonymtypedef: PSI-MOD-label "Unique short label curated by PSI-MOD" EXACT
default-namespace: protein
idspace: PR http://purl.obolibrary.org/obo/PR_
idspace: NCBITaxon http://purl.obolibrary.org/obo/NCBITaxon_
idspace: GO http://purl.obolibrary.org/obo/GO_
idspace: OBI http://purl.obolibrary.org/obo/OBI_
idspace: CHEBI http://purl.obolibrary.org/obo/CHEBI_
idspace: MOD http://purl.obolibrary.org/obo/MOD_
idspace: SO http://purl.obolibrary.org/obo/SO_
remark: Use reasoner in obo edit to see the correct hierarchy.
ontology: pr

[Term]
id: PR:000000001
name: protein
def: "An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA." [PRO:DAN, PRO:WCB]
comment: Proteins descended from a common ancestor can be classified into families and superfamilies composed of products of evolutionarily-related genes. The domain architecture of a protein is described by the order of its constituent domains. Proteins with the same domains in the same order are defined as homeomorphic [PRO:WCB].
is_a: PR:000018263 ! amino acid chain

[Term]
id: PR:000002968
name: post-translationally modified amino-acid residue
def: "A modified amino-acid residue that was modified after its incorporation into an amino acid chain." [PRO:DAN]
comment: This includes any residue modification that occurs once translation has begun, and thus includes what are usually considered co-translational modifications.
synonym: "post-translationally modified amino acid chain residue" EXACT [PRO:DAN]
synonym: "post-translationally modified protein residue" NARROW [PRO:DAN]
is_a: PR:000025513 ! modified amino-acid residue

[Term]
id: PR:000004854
name: mitotic checkpoint serine/threonine-protein kinase BUB1
def: "A BUB1/BUB1B protein that is a translation product of the human BUB1 gene or a 1:1 ortholog thereof." [PMID:22698286, PRO:CNA]
comment: Category=gene. Flag=automatic.
synonym: "BUB1" EXACT PRO-short-label [PRO:DNx]
synonym: "BUB1A" EXACT []
synonym: "BUB1L" RELATED []
synonym: "hBUB1" EXACT []
synonym: "mBUB1" EXACT []
is_a: PR:000035665 ! BUB1/BUB1B protein

[Term]
id: PR:000004856
name: mitotic checkpoint protein BUB3
def: "A protein that is a translation product of the human BUB3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene. Flag=automatic.
synonym: "BUB3" EXACT PRO-short-label [PRO:DNx]
synonym: "WD repeat type I transmembrane protein A72.5" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000005216
name: cell division cycle 5-like protein
def: "A protein that is a translation product of the human CDC5L gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene. Flag=automatic.
synonym: "cdc5-like protein" EXACT []
synonym: "CDC5L" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0432" RELATED []
synonym: "PCDC5RP" RELATED []
synonym: "pombe cdc5-related protein" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000010038
name: mitotic spindle assembly checkpoint protein MAD2A
def: "A protein that is a translation product of the human MAD2L1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene. Flag=automatic.
synonym: "HsMAD2" EXACT []
synonym: "MAD2" RELATED []
synonym: "MAD2-like protein 1" EXACT []
synonym: "Mad2a" RELATED []
synonym: "MAD2L1" EXACT PRO-short-label [PRO:DNx]
synonym: "mitotic arrest deficient 2-like protein 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000010680
name: peptide methionine sulfoxide reductase
def: "A protein that is a translation product of the human MSRA gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene. Flag=automatic.
synonym: "MSRA" EXACT PRO-short-label [PRO:DNx]
synonym: "MXR1" RELATED []
synonym: "peptide Met(O) reductase" EXACT []
synonym: "peptide-methionine (S)-S-oxide reductase" EXACT []
synonym: "PMSR" EXACT []
synonym: "protein-methionine-S-oxide reductase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000016853
name: thioredoxin
def: "A protein that is a translation product of the human TXN gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene. Flag=automatic.
synonym: "ADF" RELATED []
synonym: "ATL-derived factor" EXACT []
synonym: "SASP" EXACT []
synonym: "surface-associated sulphydryl protein" EXACT []
synonym: "TRDX" RELATED []
synonym: "Trx" EXACT []
synonym: "TRX1" RELATED []
synonym: "TXN" EXACT PRO-short-label [PRO:DNx]
synonym: "Txn1" RELATED []
is_a: PR:000000001 ! protein

[Term]
id: PR:000018263
name: amino acid chain
def: "A polymer of amino acids linked by peptide bonds." [PRO:DAN]
synonym: "peptide" NARROW []
synonym: "polypeptide" NARROW []

[Term]
id: PR:000018264
name: proteolytic cleavage product
def: "An amino acid chain produced as the result of peptide bond cleavage of a longer amino acid chain." [PRO:DAN]
synonym: "peptide" NARROW []
synonym: "polypeptide" NARROW []
is_a: PR:000018263 ! amino acid chain

[Term]
id: PR:000021935
name: immature protein part
def: "A part of a protein that is removed during the protein maturation process." [PRO:DAN]
synonym: "cleaved_peptide_region" EXACT [SO:0100011]
relationship: part_of PR:000000001 ! protein

[Term]
id: PR:000021937
name: initiator methionine
def: "An immature protein part that is the N-terminal most residue." [PRO:DAN]
comment: The initiator methionine is cleaved co-translationally. For this reason, we do not use the derives_from relation when defining protein forms lacking the initiator (because the precursor form does not yet exist at the time of removal).
is_a: PR:000021935 ! immature protein part

[Term]
id: PR:000024854
name: P-factor precursor
def: "A protein that is a translation product of the fission yeast map2 gene or a 1:1 ortholog thereof. In Schizosaccharomyces pombe 972h-, proteolytic processing yeilds four peptides - two copies of P-factor 1 and one each of P-factor 2 and P-factor 3." [PMID:8314086, PRO:MSY]
comment: Category=gene. Requested by=PomBase.
synonym: "map2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000024855
name: P-factor
def: "A proteolytic cleavage product that is derived from P-factor precursor. In Schizosaccharomyces pombe 972h- the sequence is TYADFLRAYQSWNTFVNPDRPNL, corresponding to amino acids 66-88 or 134-156 of UniProtKB:Q09180-1." [PRO:MSY]
comment: Category=modification. Requested by=PomBase.
is_a: PR:000018264 ! proteolytic cleavage product
relationship: derives_from PR:000024854 ! P-factor precursor

[Term]
id: PR:000024856
name: P-factor-like 1
def: "A proteolytic cleavage product that is derived from P-factor precursor. In Schizosaccharomyces pombe 972h- the sequence is SYADFLRVYQSWNTFANPDRPNL, corresponding to amino acids 32-54 of UniProtKB:Q09180-2." [PRO:MSY]
comment: Category=modification. Requested by=PomBase.
is_a: PR:000018264 ! proteolytic cleavage product
relationship: derives_from PR:000024854 ! P-factor precursor

[Term]
id: PR:000024857
name: P-factor-like 2
def: "A proteolytic cleavage product that is derived from P-factor precursor. In Schizosaccharomyces pombe 972h- the sequence is SYADFLRAYHSWNTFVNPDRPNL, corresponding to amino acids 100-122 of UniProtKB:Q09180-3." [PRO:MSY]
comment: Category=modification. Requested by=PomBase.
is_a: PR:000018264 ! proteolytic cleavage product
relationship: derives_from PR:000024854 ! P-factor precursor

[Term]
id: PR:000024858
name: inactivated P-factor
def: "A proteolytic cleavage product derived from P-factor by removal of the C-terminal leucine residue." [PMID:10792724, PRO:MSY]
comment: Category=gene. Requested by=PomBase.
is_a: PR:000018264 ! proteolytic cleavage product
relationship: derives_from PR:000024855 ! P-factor

[Term]
id: PR:000025000
name: M-factor precursor
def: "A protein that is a translation product of the fission yeast mfm1, mfm2, or mfm3 genes or 1:1 orthologs thereof." [PRO:MSY]
comment: Category=union. Requested by=PomBase.
is_a: PR:000000001 ! protein
union_of: PR:000025003 ! M-factor precursor mfm1
union_of: PR:000025004 ! M-factor precursor mfm2
union_of: PR:000025005 ! M-factor precursor mfm3

[Term]
id: PR:000025001
name: M-factor
def: "A proteolytic cleavage product that is derived from propeptide removal from M-factor precursor, farnesylated 1. In Schizosaccharomyces pombe 972h- the sequence is YTPKVPYMC, with a farnesylated C-terminal residue." [PMID:1547790, PMID:8196631, PRO:MSY]
comment: Category=union. Requested by=PomBase.

[Term]
id: PR:000025002
name: M-factor precursor, farnesylated 1
def: "An M-factor precursor that is farnesylated at the C-terminal-most cysteine residue." [PRO:MSY]
comment: Category=modification. Requested by=PomBase.
is_a: PR:000024857 ! P-factor-like 2

[Term]
id: PR:000025003
name: M-factor precursor mfm1
def: "A protein that is a translation product of the fission yeast mfm1 gene or a 1:1 ortholog thereof." [PRO:MSY]
comment: Category=gene. Requested by=PomBase.
synonym: "mfm1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000025004
name: M-factor precursor mfm2
def: "A protein that is a translation product of the fission yeast mfm2 gene or a 1:1 ortholog thereof." [PRO:MSY]
comment: Category=gene. Requested by=PomBase.
synonym: "mfm2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000025005
name: M-factor precursor mfm3
def: "A protein that is a translation product of the fission yeast mfm3 gene or a 1:1 ortholog thereof." [PRO:MSY]
comment: Category=gene. Requested by=PomBase.
synonym: "mfm3" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000025513
name: modified amino-acid residue
def: "An amino-acid residue that is covalently modified by chemical alteration to the side chain or backbone atoms." [PRO:DAN]
synonym: "modified amino acid chain residue" EXACT [PRO:DAN]
synonym: "modified protein residue" NARROW [PRO:DAN]

[Term]
id: PR:000027498
name: p38-like stress-activated mitogen-activated protein kinase
def: "A protein that contains a single copy of the Protein kinase domain (PF00069) and is a fungal mitogen-activated protein kinase activated when cells are challenged with a variety of environmental stresses, such as osmotic, oxidative, and heat stress." [KinBase:p38, PMID:10207620, PRO:CNA]
comment: Category=family.
synonym: "HOG1-like map kinase" EXACT []
synonym: "HOG1-like mitogen-activated protein kinase" EXACT []
synonym: "p38 subfamily of MAPK" RELATED []
synonym: "SAPK" RELATED []
xref: PIRSF:PIRSF501111
is_a: PR:000000001 ! protein

[Term]
id: PR:000027499
name: mitogen-activated protein kinase HOG1
def: "A p38-like stress-activated mitogen-activated protein kinase that is a translation product of the yeast HOG1 gene or a 1:1 ortholog thereof." [PMID:10207620, PRO:CNA]
comment: Category=gene. Flag=automatic. The gene HOG1 in S. pombe is named sty1.
synonym: "HOG1" EXACT PRO-short-label [PRO:DNx]
synonym: "MAP kinase spc1" EXACT []
synonym: "STY1" RELATED []
is_a: PR:000027498 ! p38-like stress-activated mitogen-activated protein kinase

[Term]
id: PR:000027500
name: mitogen-activated protein kinase sty1 (fission yeast)
def: "A mitogen-activated protein kinase HOG1 that is encoded in the genome of fission yeast." [PMID:7501024, PomBase:MAH]
comment: Category=organism-gene. Flag=automatic. HOG1 in S. pombe is named sty1.
synonym: "HOG1" RELATED []
synonym: "PHH1" RELATED []
synonym: "SPAC24B11.06C" RELATED []
synonym: "SPC1" RELATED []
synonym: "Spom972h-HOG1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q09892

[Term]
id: PR:000027501
name: mitogen-activated protein kinase HOG1 phosphorylated form
def: "A mitogen-activated protein kinase HOG1 that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "HOG1/PhosRes+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027502
name: mitogen-activated protein kinase HOG1 phosphorylated 1
def: "A mitogen-activated protein kinase HOG1 phosphorylated form that has been phosphorylated at the Thr and Tyr residues of the MAP kinase activation motif TxY." [PMID:20729203, PRO:CNA]
comment: Category=modification.
synonym: "active HOG1" EXACT []
synonym: "HOG1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027501 ! mitogen-activated protein kinase HOG1 phosphorylated form

[Term]
id: PR:000027503
name: mitogen-activated protein kinase sty1 phosphorylated 1 (fission yeast)
def: "A mitogen-activated protein kinase sty1 phosphorylated 1 in fission yeast. Phosphorylated on TxY motif by MAPK kinase (Wis1). UniProtKB:Q09892-1, Thr-171, MOD:00047|Tyr-173, MOD:00048." [PMID:20729203, PMID:7501024, PMID:9251044, PomBase:MAH]
comment: Category=organism-modification. Flag=automatic.
synonym: "active PHH1" EXACT []
synonym: "active spc1" EXACT []
synonym: "active sty1" EXACT []
synonym: "Spom972h-HOG1/Phos:1" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027504
name: mitogen-activated protein kinase HOG1 unmodified form
def: "A mitogen-activated protein kinase HOG1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification.
synonym: "HOG1/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027505
name: mitogen-activated protein kinase sty1 unmodified form (fission yeast)
def: "A mitogen-activated protein kinase HOG1 unmodified form in fission yeast." [PRO:CNA]
comment: Category=organism-modification.
synonym: "Spom972h-HOG1/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027506
name: M-phase inducer phosphatase
def: "A protein that is a translation product of the fission yeast cdc25 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. Flag=automatic. CDC25 is named MIH1 in yeast.
synonym: "CDC25" RELATED []
synonym: "cdc25" EXACT PRO-short-label [PRO:DNx]
synonym: "MIH1" RELATED []
synonym: "Mitosis initiation protein" EXACT []
synonym: "P80" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000027507
name: M-phase inducer phosphatase (fission yeast)
def: "An M-phase inducer phosphatase that is encoded in the genome of fission yeast." [PMID:9774107, PomBase:MAH]
comment: Category=organism-gene.
synonym: "SPAC24H6.05" RELATED []
synonym: "Spom972h-cdc25" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P06652

[Term]
id: PR:000027508
name: M-phase inducer phosphatase unmodified form
def: "An M-phase inducer phosphatase that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification.
synonym: "cdc25/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027509
name: M-phase inducer phosphatase unmodified form (fission yeast)
def: "An M-phase inducer phosphatase unmodified form in fission yeast." [PMID:9774107, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-cdc25/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027510
name: M-phase inducer phosphatase phosphorylated form
def: "An M-phase inducer phosphatase that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "cdc25/PhosRes+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027511
name: M-phase inducer phosphatase phosphorylated 1
def: "An M-phase inducer phosphatase phosphorylated form that has been phosphorylated at the Ser residues within the canonical 14-3-3 binding motifs. Example: UniProtKB:P06652-1, Ser-99/Ser-192/Ser-359, MOD:00046." [PMID:9774107, PRO:CNA]
comment: Category=modification.
synonym: "cdc25/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027510 ! M-phase inducer phosphatase phosphorylated form

[Term]
id: PR:000027512
name: M-phase inducer phosphatase phosphorylated 1 (fission yeast)
def: "An M-phase inducer phosphatase phosphorylated 1 in fission yeast. This form is produced by phosphorylation by Cds1 or Chk1 during replication checkpoint. UniProtKB:P06652-1, Ser-99/Ser-192/Ser-359, MOD:00046." [PMID:9774107, PomBase:MAH]
comment: Category=organism-modification. Ser-192 is a minor phosphorylation site.
synonym: "Spom972h-cdc25/Phos:1" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027513
name: transcriptional regulator prz1
def: "A protein that is a translation product of the fission yeast prz1 gene or a 1:1 ortholog thereof." [PMID:12637524, PRO:CNA]
comment: Category=gene.
synonym: "Pbp1-responsive zinc finger protein 1" EXACT []
synonym: "prz1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000027514
name: transcriptional regulator prz1 (fission yeast)
def: "A transcriptional regulator prz1 that is encoded in the genome of fission yeast." [PMID:12637524, PomBase:MAH]
comment: Category=organism-gene.
synonym: "SPAC4G8.13C" RELATED []
synonym: "Spom972h-prz1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q09838

[Term]
id: PR:000027515
name: transcriptional regulator prz1 unmodified form
def: "A transcriptional regulator prz1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification.
synonym: "prz1/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027516
name: transcriptional regulator prz1 unmodified form (fission yeast)
def: "A transcriptional regulator prz1 unmodified form in fission yeast." [PMID:12637524, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-prz1/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027517
name: anaphase spindle elongation protein 1
def: "A protein that is a translation product of the fission yeast ase1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. Flag=automatic.
synonym: "ase1" EXACT PRO-short-label [PRO:DNx]
synonym: "Ase1p" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000027518
name: anaphase spindle elongation protein 1 (fission yeast)
def: "An anaphase spindle elongation protein 1 that is encoded in the genome of fission yeast." [PMID:19686686, PomBase:MAH]
comment: Category=organism-gene. Flag=automatic.
synonym: "SPAPB1A10.09" RELATED []
synonym: "Spom972h-ase1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9HDY1

[Term]
id: PR:000027519
name: anaphase spindle elongation protein 1 unmodified form
def: "An anaphase spindle elongation protein 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification.
synonym: "ase1/UnMod" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027517 ! anaphase spindle elongation protein 1

[Term]
id: PR:000027520
name: anaphase spindle elongation protein 1 unmodified form (fission yeast)
def: "An anaphase spindle elongation protein 1 unmodified form in fission yeast." [PMID:19686686, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-ase1/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027521
name: anaphase spindle elongation protein 1 phosphorylated 1
def: "An anaphase spindle elongation protein 1 phosphorylated form that has been modified on cdc2-dependent phosphorylation sites. Example: UniProtKB:Q9HDY1-1, Ser-640/Ser-683/Ser-688/Ser-693, MOD:00046." [PMID:19686686, PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "ase1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027531 ! anaphase spindle elongation protein 1 phosphorylated form

[Term]
id: PR:000027522
name: anaphase spindle elongation protein 1 phosphorylated 1 (fission yeast)
def: "An anaphase spindle elongation protein 1 phosphorylated 1 in fission yeast. UniProtKB:Q9HDY1-1, Ser-640/Ser-683/Ser-688/Ser-693, MOD:00046." [PMID:18257517, PMID:19686686, PomBase:MAH]
comment: Category=organism-modification. Flag=automatic.
synonym: "Spom972h-ase1/Phos:1" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027523
name: DNA replication regulator sld2
def: "A protein that is a translation product of the yeast SLD2 gene or a 1:1 ortholog thereof." [PMID:11937031, PRO:CNA]
comment: Category=gene. In fission yeast SLD2 is called DRC1.
synonym: "DNA replication and checkpoint protein 1" EXACT []
synonym: "DRC1" RELATED []
synonym: "SLD2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000027524
name: DNA replication regulator sld2 (fission yeast)
def: "A DNA replication regulator sld2 that is encoded in the genome of fission yeast." [PMID:11937031, PomBase:MAH]
comment: Category=organism-gene. Flag=automatic.
synonym: "DNA replication regulator drc1" EXACT []
synonym: "SPAC6B12.11" RELATED []
synonym: "Spom972h-SLD2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14216

[Term]
id: PR:000027525
name: DNA replication regulator sld2 unmodified form
def: "A DNA replication regulator sld2 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification.
synonym: "SLD2/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027526
name: DNA replication regulator sld2 unmodified form (fission yeast)
def: "A DNA replication regulator sld2 unmodified form in fission yeast." [PMID:11937031, PomBase:MAH]
comment: Category=organism-modification.
synonym: "DNA replication regulator drc1 unmodified form (fission yeast)" EXACT []
synonym: "Spom972h-SLD2/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027527
name: DNA replication regulator sld2 phosphorylated form
def: "A DNA replication regulator sld2 that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "SLD2/PhosRes+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027528
name: DNA replication regulator sld2 phosphorylated 1
def: "A DNA replication regulator sld2 phosphorylated form that has been phosphorylated on the [ST]P[KR][KR] cyclin-dependent kinase motifs. Example: UniProtKB:O14216-1, Thr-60/Thr-74/Thr-99/Thr-154, MOD:00047|Ser-87, MOD:00046." [PMID:11937031, PRO:CNA]
comment: Category=modification.
synonym: "SLD2/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027527 ! DNA replication regulator sld2 phosphorylated form

[Term]
id: PR:000027529
name: DNA replication regulator sld2 phosphorylated 1 (fission yeast)
def: "A DNA replication regulator sld2 phosphorylated 1 in fission yeast. UniProtKB:O14216-1, Thr-60/Thr-74/Thr-99/Thr-154, MOD:00047|Ser-87, MOD:00046." [PMID:11937031, PomBase:MAH]
comment: Category=organism-modification.
synonym: "DNA replication regulator drc1 phosphorylated 1" EXACT []
synonym: "Spom972h-SLD2/Phos:1" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027530
name: transcriptional regulator prz1 phosphorylated form
def: "A transcriptional regulator prz1 phosphorylated form that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "prz1/PhosRes+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027531
name: anaphase spindle elongation protein 1 phosphorylated form
def: "An anaphase spindle elongation protein 1 that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "ase1/PhosRes+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027517 ! anaphase spindle elongation protein 1

[Term]
id: PR:000027532
name: transcriptional regulator prz1 phosphorylated 1
def: "A transcriptional regulator prz1 phosphorylated form that is hyperphosphorylated under conditions where calcineurin is not active." [PMID:12637524, PRO:CNA]
comment: Category=modification.
synonym: "prz1 hyperphosphorylated" EXACT []
synonym: "prz1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027530 ! transcriptional regulator prz1 phosphorylated form

[Term]
id: PR:000027533
name: transcriptional regulator prz1 isoform 1 phosphorylated 1 (fission yeast)
def: "A transcriptional regulator prz1 phosphorylated 1 in fission yeast. UniProtKB:Q09838-1, MOD:00696." [PMID:12637524, PomBase:MAH]
comment: Category=organism-modification.

[Term]
id: PR:000027538
name: transcription factor ste11
def: "A protein that is a translation product of the fission yeast ste11 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. Flag=automatic.
synonym: "STE11" RELATED []
synonym: "ste11" EXACT PRO-short-label [PRO:DNx]
synonym: "STEX" RELATED []
is_a: PR:000000001 ! protein

[Term]
id: PR:000027539
name: transcription factor ste11 (fission yeast)
def: "A transcription factor ste11 that is encoded in the genome of fission yeast." [PMID:11702950, PomBase:MAH]
comment: Category=organism-gene. Flag=automatic.
synonym: "SPBC32C12.02" RELATED []
synonym: "Spom972h-ste11" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P36631

[Term]
id: PR:000027540
name: transcription factor ste11 unmodified form
def: "A transcription factor ste11 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification.
synonym: "ste11/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027541
name: transcription factor ste11 unmodified form (fission yeast)
def: "A transcription factor ste11 unmodified form unmodified form in fission yeast." [PMID:11702950, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-ste11/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027542
name: transcription factor ste11 phosphorylated 1
def: "A transcription factor ste11 phosphorylated form that has been phosphorylated at the consensus recognition sequence for 14-3-3. Example: UniProtKB:P36631-1, Thr-173, MOD:00047|Ser-218, MOD:00046." [PMID:11702950, PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "ste11/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027544 ! transcription factor ste11 phosphorylated form

[Term]
id: PR:000027543
name: transcription factor ste11 phosphorylated 1 (fission yeast)
def: "A transcription factor ste11 phosphorylated 1 in fission yeast. Phosphorylated by Pat1 kinase. UniProtKB:P36631-1, Thr-173, MOD:00047|Ser-218, MOD:00046." [PMID:11702950, PomBase:MAH]
comment: Category=organism-modification. Flag=automatic.
synonym: "Spom972h-ste11/Phos:1" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027544
name: transcription factor ste11 phosphorylated form
def: "A transcription factor ste11 that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "ste11/PhosRes+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027545
name: histone H2A.2
def: "A histone H2A that is a translation product of the yeast HTA2 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. This protein is called histone H2A-beta in fission yeast.
synonym: "H2A.2" EXACT []
synonym: "H2A2" RELATED []
synonym: "HTA2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027547 ! histone H2A

[Term]
id: PR:000027546
name: histone H2A-beta (fission yeast)
def: "A histone H2A.2 that is encoded in the genome of fission yeast." [PMID:15226425, PMID:19965387, PMID:21516229, PomBase:MAH]
comment: Category=organism-gene. Flag=automatic.
synonym: "SPAC19G12.06C" RELATED []
synonym: "Spom972h-HTA2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P04910

[Term]
id: PR:000027547
name: histone H2A
def: "A protein that is a translational product of one of the H2A gene variants. It is a core histone and contains a copy of the Histone (PF00125) domain." [PMID:18443735, PMID:19234519, PRO:CNA]
comment: Category=family.
xref: PIRSF:PIRSF002048
is_a: PR:000000001 ! protein

[Term]
id: PR:000027548
name: histone H2A.2 unmodified form
def: "A histone H2A.2 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification.
synonym: "HTA2/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027549
name: histone H2A-beta unmodified form (fission yeast)
def: "A histone H2A.2 unmodified form in fission yeast." [PMID:15226425, PMID:19965387, PMID:21516229, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-HTA2/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027550
name: histone H2A.2 phosphorylated 1
def: "A histone H2A.2 phosphorylated form that has been phosphorylated on the [ST]Q motif at the C-terminus that constitutes a recognition sequence for kinases from the PI3/PI4-kinase family. Phosphorylated in response to DNA double-strand breaks generated by exogenous genotoxic agents and by stalled replication forks. Example: UniProtKB:P04910-1, Ser-128, MOD:00046." [PMID:15226425, PMID:21516229, PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "gamma-H2A" RELATED []
synonym: "H2AS128ph" RELATED []
synonym: "HTA2/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027552 ! histone H2A.2 phosphorylated form

[Term]
id: PR:000027551
name: histone H2A-beta phosphorylated 1 (fission yeast)
def: "A histone H2A.2 phosphorylated 1 in fission yeast. Phosphorylation motif is SQE. UniProtKB:P04910-1, Ser-128, MOD:00046." [PMID:15226425, PMID:21516229, PomBase:MAH]
comment: Category=organism-modification.
synonym: "gamma-H2A (fission yeast)" RELATED []
synonym: "histone H2A.2 phosphorylated 1 (fission yeast)" EXACT []
synonym: "Spom972h-HTA2/Phos:1" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027552
name: histone H2A.2 phosphorylated form
def: "A histone H2A.2 that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "HTA2/PhosRes+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027556
name: histone H2A.2 phosphorylated 2
def: "A histone H2A-beta phosphorylated form that has been phosphorylated at the Ser or Thr residue within the LLPKx[ST] motif by the mitotic checkpoint serine/threonine-protein kinase BUB1. Example: UniProtKB:P04910-1, Ser-122, MOD:00046." [PMID:19965387, PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "HTA2/Phos:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027552 ! histone H2A.2 phosphorylated form

[Term]
id: PR:000027557
name: histone H2A-beta phosphorylated 2 (fission yeast)
def: "A histone H2A.2 phosphorylated 2 in fission yeast. UniProtKB:P04910-1, Ser-122, MOD:00046." [PMID:19965387, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-HTA2/Phos:2" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027558
name: histone H2A-alpha
def: "A histone H2A that is a translation product of the fission yeast hta1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. This protein is called histone H2A-alpha in fission yeast.
synonym: "H2A.1" EXACT []
synonym: "histone H2A-alpha" EXACT []
synonym: "hta1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027547 ! histone H2A

[Term]
id: PR:000027559
name: histone H2A-alpha (fission yeast)
def: "A histone H2A.1 that is encoded in the genome of fission yeast." [PMID:15226425, PMID:19965387, PMID:21516229, PomBase:MAH]
comment: Category=organism-gene. Flag=automatic.
synonym: "SPCC622.08C" RELATED []
synonym: "Spom972h-hta1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P04909

[Term]
id: PR:000027560
name: histone H2A-alpha unmodified form
def: "A histone H2A.1 which lacks phosphorylated residues." [PRO:CNA]
comment: Category=modification.
synonym: "hta1/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027561
name: histone H2A-alpha unmodified form (fission yeast)
def: "A histone H2A-alpha unmodified form in fission yeast." [PMID:15226425, PMID:19965387, PMID:21516229, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-hta1/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027562
name: histone H2A-alpha phosphorylated form
def: "A histone H2A-alpha that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "histone H2A.1 phosphorylated form" EXACT []
synonym: "hta1/PhosRes+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027563
name: histone H2A-alpha phosphorylated 1
def: "A histone H2A-alpha phosphorylated form that has been phosphorylated on the [ST]Q motif at the C-terminus that constitutes a recognition sequence for kinases from the PI3/PI4-kinase family. Phosphorylated in response to DNA double-strand breaks generated by exogenous genotoxic agents and by stalled replication forks. Example: UniProtKB:P04909-1, Ser-129, MOD:00046." [PMID:15226425, PMID:21516229, PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "gamma-H2A" RELATED []
synonym: "H2AS128ph" RELATED []
synonym: "histone H2A.1 phosphorylated 1" EXACT []
synonym: "hta1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027562 ! histone H2A-alpha phosphorylated form

[Term]
id: PR:000027564
name: histone H2A-alpha phosphorylated 1 (fission yeast)
def: "A histone H2A-alpha phosphorylated 1 in fission yeast. Phosphorylation motif is SQE. UniProtKB:P04909-1, Ser-129, MOD:00046." [PMID:15226425, PMID:21516229, PomBase:MAH]
comment: Category=organism-modification.
synonym: "gamma-H2A (fission yeast)" RELATED []
synonym: "histone H2A.1 phosphorylated 1 (fission yeast)" EXACT []
synonym: "Spom972h-hta1/Phos:1" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027565
name: histone H2A-alpha phosphorylated 2
def: "A histone H2A.1 phosphorylated form that has been phosphorylated at the Ser or Thr residue within the LLPKx[ST] motif by the mitotic checkpoint serine/threonine-protein kinase BUB1. Example: UniProtKB:P04909-1, Ser-122, MOD:00046." [PMID:19965387, PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "histone H2A.1 phosphorylated 2" EXACT []
synonym: "hta1/Phos:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027562 ! histone H2A-alpha phosphorylated form

[Term]
id: PR:000027566
name: histone H2A-alpha phosphorylated 2 (fission yeast)
def: "A histone H2A-alpha phosphorylated 2 in fission yeast. UniProtKB:P04909-1, Ser-122, MOD:00046." [PMID:19965387, PomBase:MAH]
comment: Category=organism-modification.
synonym: "histone H2A.1 phosphorylated 2 (fission yeast)" EXACT []
synonym: "Spom972h-hta1/Phos:2" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027567
name: meiosis protein mei2
def: "A protein that is a translation product of the fission yeast mei2 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. Flag=automatic.
synonym: "mei2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000027568
name: meiosis protein mei2 (fission yeast)
def: "A meiosis protein mei2 that is encoded in the genome of fission yeast." [PMID:9062192, PomBase:MAH]
comment: Category=organism-gene. Flag=automatic.
synonym: "SPAC27D7.03C" RELATED []
synonym: "Spom972h-mei2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P08965

[Term]
id: PR:000027569
name: histone H3.1
def: "A histone H3 that is a translation product of the fission yeast hht1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. Flag=automatic.
synonym: "hht1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027594 ! histone H3

[Term]
id: PR:000027570
name: histone H3.1 (fission yeast)
def: "A histone H3.1 that is encoded in the genome of fission yeast." [PMID:11242054, PMID:20929775, PomBase:MAH]
comment: Category=organism-gene. Flag=automatic.
synonym: "SPAC1834.04" RELATED []
synonym: "Spom972h-hht1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P09988

[Term]
id: PR:000027571
name: histone H3.2
def: "A histone H3 that is a translation product of the fission yeast hht2 gene or a 1:1 ortholog thereof." [PMID:11242054, PMID:20929775, PRO:CNA]
comment: Category=gene. Flag=automatic.
synonym: "hht2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027594 ! histone H3

[Term]
id: PR:000027572
name: histone H3.2 (fission yeast)
def: "A histone H3.2 that is encoded in the genome of fission yeast." [PMID:11242054, PMID:20929775, PomBase:MAH]
comment: Category=organism-gene. Flag=automatic.
synonym: "SPBC8D2.04, PI060" RELATED []
synonym: "Spom972h-hht2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P09988

[Term]
id: PR:000027573
name: histone H3.1, initiator methionine removed form
def: "A histone H3.1 that has had the initiator methionine removed." [PRO:CNA]
comment: Category=modification.
synonym: "hht1/InitMet-" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027574
name: histone H3.1, initiator methionine removed form (fission yeast)
def: "A histone H3.1, initiator methionine removed form in fission yeast." [PMID:11242054, PMID:20929775, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-hht1/InitMet-" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027575
name: histone H3.1, initiator methionine removed phosphorylated 1
def: "A histone H3.1, initiator methionine removed form which has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "H3-pT3" RELATED []
synonym: "hht1/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027573 ! histone H3.1, initiator methionine removed form

[Term]
id: PR:000027576
name: histone H3.1, initiator methionine removed phosphorylated 1 (fission yeast)
def: "A histone H3.1, initiator methionine removed phosphorylated 1 in fission yeast. Phosphorylated by Haspin. UniProtKB:P09988-1, 2-136, Thr-4, MOD:00047." [PMID:20929775, PomBase:MAH]
comment: Category=organism-modification. Note that this form is referred to H3-pT3, because the initial methionine is not counted.
synonym: "H3-pT3" RELATED []
synonym: "Spom972h-hht1/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027577
name: histone H3.1, initiator methionine removed methylated 1
def: "A histone H3.1, initiator methionine removed which has at least one methylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "hht1/InitMet-/Me:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027573 ! histone H3.1, initiator methionine removed form

[Term]
id: PR:000027578
name: histone H3.1, initiator methionine removed methylated 1 (fission yeast)
def: "A histone H3.1, initiator methionine removed methylated 1 in fission yeast. Methylated by HP1. UniProtKB:P09988-1, 2-136, Lys-10, MOD:00663." [PMID:11242054, PomBase:MAH]
comment: Category=organism-modification. Note that in the article cited residue number is different because the initial methionine is not counted.
synonym: "Spom972h-hht1/InitMet-/Me:1" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027579
name: histone H3.2, initiator methionine removed form
def: "A histone H3.2 that has had the initiator methionine removed." [PRO:CNA]
comment: Category=modification.
synonym: "hht2/InitMet-" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027580
name: histone H3.2, initiator methionine removed form (fission yeast)
def: "A histone H3.2, initiator methionine removed form in fission yeast." [PMID:11242054, PMID:20929775, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-hht2/InitMet-" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027581
name: histone H3.1, initiator methionine removed unphosphorylated form
def: "A histone H3.1, initiator methionine removed which lacks phosphorylated residues." [PRO:CNA]
comment: Category=modification.
synonym: "hht1/InitMet-/PhosRes-" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027582
name: meiosis protein mei2 unmodified form
def: "A meiosis protein mei2 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification.
synonym: "mei2/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027583
name: meiosis protein mei2 unmodified form (fission yeast)
def: "A meiosis protein mei2 unmodified form in fission yeast." [PMID:9062192, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-mei2/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027584
name: meiosis protein mei2 phosphorylated form
def: "A meiosis protein mei2 that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "mei2/PhosRes+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027585
name: meiosis protein mei2 phosphorylated 1
def: "A meiosis protein mei2 phosphorylated form that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "mei2/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027584 ! meiosis protein mei2 phosphorylated form

[Term]
id: PR:000027586
name: meiosis protein mei2 phosphorylated 1 (fission yeast)
def: "A meiosis protein mei2 phosphorylated 1 in fission yeast. Phosphorylated by Pat1 kinase. UniProtKB:P08965-1, Ser-438, MOD:00046|Thr-527, MOD:00047." [PMID:9062192, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-mei2/Phos:1" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027587
name: histone H3.1, initiator methionine removed unphosphorylated form (fission yeast)
def: "A histone H3.1, initiator methionine removed unphosphorylated form in fission yeast. Example: UniProtKB:P09988-1, 2-136." [PMID:11242054, PMID:20929775, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-hht1/InitMet-/PhosRes-" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027588
name: histone H3.2, initiator methionine removed unphosphorylated form
def: "A histone H3.2, initiator methionine removed which lacks phosphorylated residues." [PRO:CNA]
comment: Category=modification.
synonym: "hht2/InitMet-/PhosRes-" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027589
name: histone H3.2, initiator methionine removed unphosphorylated form (fission yeast)
def: "A histone H3.2, initiator methionine removed unphosphorylated form in fission yeast. Example: UniProtKB:P09988-1, 2-136." [PMID:11242054, PMID:20929775, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-hht2/InitMet-/PhosRes-" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027590
name: histone H3.2, initiator methionine removed phosphorylated 1
def: "A histone H3.2, initiator methionine removed form which has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "H3-pT3" RELATED []
synonym: "hht2/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027579 ! histone H3.2, initiator methionine removed form

[Term]
id: PR:000027591
name: histone H3.2, initiator methionine removed phosphorylated 1 (fission yeast)
def: "A histone H3.2, initiator methionine removed phosphorylated 1 in fission yeast. Phosphorylated by Haspin. UniProtKB:P09988-1, 2-136, Thr-4, MOD:00047." [PMID:20929775, PomBase:MAH]
comment: Category=organism-modification. Note that this form is referred to H3-pT3, because the initial methionine is not counted.
synonym: "H3-pT3" RELATED []
synonym: "Spom972h-hht2/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027592
name: histone H3.2, initiator methionine removed methylated 1
def: "A histone H3.2, initiator methionine removed which has at least one methylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "hht2/InitMet-/Me:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027579 ! histone H3.2, initiator methionine removed form

[Term]
id: PR:000027593
name: histone H3.2, initiator methionine removed methylated 1 (fission yeast)
def: "A histone H3.2, initiator methionine removed methylated 1 in fission yeast. Methylated by HP1. UniProtKB:P09988-1, 2-136, Lys-10, MOD:00663." [PMID:11242054, PomBase:MAH]
comment: Category=organism-modification. Note that in the article cited residue number is different because the initial methionine is not counted.
synonym: "Spom972h-hht2/InitMet-/Me:1" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027594
name: histone H3
def: "A protein that is a translational product of one of the H3 gene variants. It is a core histone and contains a copy of the Histone (PF00125) domain at its C-terminus." [PMID:18443735, PMID:19234519, PRO:CNA]
comment: Category=family.
xref: PIRSF:PIRSF002051
is_a: PR:000000001 ! protein

[Term]
id: PR:000027595
name: fungal histone H3.3
def: "A histone H3 that is a translation product of the fission yeast hht3 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. Flag=automatic. This term name is preceeded by fungal to distinguish from PR:000008425.
synonym: "hht3" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027594 ! histone H3

[Term]
id: PR:000027596
name: fungal histone H3.3 (fission yeast)
def: "A fungal histone H3.3 that is encoded in the genome of fission yeast." [PMID:11242054, PMID:20929775, PomBase:MAH]
comment: Category=organism-gene. Flag=automatic.
synonym: "Spom972h-hht3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10651

[Term]
id: PR:000027597
name: fungal histone H3.3, initiator methionine removed form
def: "A fungal histone H3.3 that has had the initiator methionine removed." [PRO:CNA]
comment: Category=modification.
synonym: "hht3/InitMet-" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027598
name: fungal histone H3.3, initiator methionine removed form (fission yeast)
def: "A fungal histone H3.3, initiator methionine removed form in fission yeast." [PMID:11242054, PMID:20929775, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-hht3/InitMet-" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027599
name: fungal histone H3.3, initiator methionine removed unphosphorylated form
def: "A fungal histone H3.3, initiator methionine removed which lacks phosphorylated residues." [PRO:CNA]
comment: Category=modification.
synonym: "hht3/InitMet-/PhosRes-" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027600
name: fungal histone H3.3, initiator methionine removed unphosphorylated form (fission yeast)
def: "A fungal histone H3.3, initiator methionine removed unphosphorylated form in fission yeast. Example: UniProtKB:P10651-1, 2-136." [PMID:11242054, PMID:20929775, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-hht3/InitMet-/PhosRes-" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027601
name: fungal histone H3.3, initiator methionine removed phosphorylated 1
def: "A fungal histone H3.3, initiator methionine removed form which has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "H3-pT3" RELATED []
synonym: "hht3/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027597 ! fungal histone H3.3, initiator methionine removed form

[Term]
id: PR:000027602
name: fungal histone H3.3, initiator methionine removed phosphorylated 1 (fission yeast)
def: "A fungal histone H3.3, initiator methionine removed phosphorylated 1 in fission yeast. Phosphorylated by Haspin. UniProtKB:P10651-1, 2-136, Thr-4, MOD:00047." [PMID:20929775, PomBase:MAH]
comment: Category=organism-modification. Note that this form is referred to H3-pT3, because the initial methionine is not counted.
synonym: "H3-pT3" RELATED []
synonym: "Spom972h-hht3/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027603
name: fungal histone H3.3, initiator methionine removed methylated 1
def: "A fungal histone H3.3, initiator methionine removed which has at least one methylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "hht3/InitMet-/Me:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027597 ! fungal histone H3.3, initiator methionine removed form

[Term]
id: PR:000027604
name: fungal histone H3.3, initiator methionine removed methylated 1 (fission yeast)
def: "A fungal histone H3.3, initiator methionine removed methylated 1 in fission yeast. Methylated by HP1. UniProtKB:P10651-1, 2-136, Lys-10, MOD:00663." [PMID:11242054, PomBase:MAH]
comment: Category=organism-modification. Note that in the article cited residue number is different because the initial methionine is not counted.
synonym: "Spom972h-hht3/InitMet-/Me:1" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027605
name: mediator of replication checkpoint protein 1
def: "A protein that is a translation product of the fission yeast mrc1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. Flag=automatic.
synonym: "DNA replication checkpoint mediator mrc1" EXACT []
synonym: "mrc1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000027606
name: mediator of replication checkpoint protein 1 (fission yeast)
def: "A mediator of replication checkpoint protein 1 that is encoded in the genome of fission yeast." [PMID:14585996, PomBase:MAH]
comment: Category=organism-gene. Flag=automatic.
synonym: "SPAC694.06C" RELATED []
synonym: "Spom972h-mrc1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9P7T4

[Term]
id: PR:000027607
name: mediator of replication checkpoint protein 1 unmodified form
def: "A mediator of replication checkpoint protein 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification.
synonym: "mrc1/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027608
name: mediator of replication checkpoint protein 1 unmodified form (fission yeast)
def: "A mediator of replication checkpoint protein 1 unmodified form in fission yeast." [PMID:14585996, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-mrc1/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027609
name: mediator of replication checkpoint protein 1 phosphorylated 1
def: "A mediator of replication checkpoint protein 1 phosphorylated form that has been phosphorylated at least in the third Thr or Ser residue within the [ST]Qx[ST]Qx(6-7)[ST]Q motif in the second [ST]Q cluster. Example: UniProtKB:Q9P7T4-1, Thr-645, MOD:00047." [PMID:14585996, PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "mrc1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027611 ! mediator of replication checkpoint protein 1 phosphorylated form

[Term]
id: PR:000027610
name: mediator of replication checkpoint protein 1 phosphorylated 1 (fission yeast)
def: "A mediator of replication checkpoint protein 1 phosphorylated 1 in fission yeast. Phosphorylated at least on the last Thr residue within the TQxSQx(6)TQ motif. Phosphorylated by Rad3 and Tel1. UniProtKB:Q9P7T4-1, Thr-645, MOD:00047." [PMID:14585996, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-mrc1/Phos:1" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027611
name: mediator of replication checkpoint protein 1 phosphorylated form
def: "A mediator of replication checkpoint protein 1 that has been post-translationally modified to include at least one phosphorylated residue in any of the [ST]Q motifs." [PMID:14585996, PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "mrc1/PhosRes+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027612
name: mediator of replication checkpoint protein 1 phosphorylated 2
def: "A mediator of replication checkpoint protein 1 phosphorylated form that has been phosphorylated at least in the second Ser residue within the 3S region of the first [ST]Q clusters. Example: UniProtKB:Q9P7T4-1, Ser-604, MOD:00046." [PMID:14585996, PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "mrc1/Phos:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027611 ! mediator of replication checkpoint protein 1 phosphorylated form

[Term]
id: PR:000027613
name: mediator of replication checkpoint protein 1 phosphorylated 2 (fission yeast)
def: "A mediator of replication checkpoint protein 1 phosphorylated 2 in fission yeast. Phosphorylated by Rad3 and Tel1. UniProtKB:Q9P7T4-1, Ser-604, MOD:00046." [PMID:14585996, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-mrc1/Phos:2" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027614
name: transcription factor zip1
def: "A protein that is a translation product of the fission yeast zip1 gene or a 1:1 ortholog thereof." [PMID:15660136, PRO:CNA]
comment: Category=gene. Flag=automatic.
synonym: "SPAC25G10.03" RELATED []
synonym: "zip1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000027615
name: transcription factor zip1 (fission yeast)
def: "A transcription factor zip1 that is encoded in the genome of fission yeast." [PMID:15660136, PRO:CNA]
comment: Category=organism-gene. Flag=automatic.
synonym: "SPAC25G10.03" RELATED []
synonym: "Spom972h-zip1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q10424

[Term]
id: PR:000027616
name: transcription factor zip1 unmodified form
def: "A transcription factor zip1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification.
synonym: "zip1/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027617
name: transcription factor zip1 unmodified form (fission yeast)
def: "A transcription factor zip1 unmodified form in fission yeast." [PMID:15660136, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-zip1/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027618
name: transcription factor zip1 phosphorylated form
def: "A transcription factor zip1 that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "zip1/PhosRes+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027619
name: transcription factor zip1 phosphorylated form (fission yeast)
def: "A transcription factor zip1 phosphorylated form in fission yeast. UniProtKB:Q10424-1, MOD:00696." [PMID:15660136, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-zip1/PhosRes+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027620
name: transcription factor zip1 ubiquitinated form
def: "A transcription factor zip1 that has been post-translationally modified to include at least one ubiquitinated residue." [PRO:CNA]
comment: Category=modification.
synonym: "zip1/UbiqLys+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027621
name: transcription factor zip1 ubiquitinated form (fission yeast)
def: "A transcription factor zip1 ubiquitinated form in fission yeast. Ubiquitinated by SCF(Pof1). UniProtKB:Q10424-1, MOD:01148." [PMID:15660136, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-zip1/UbiqLys+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027622
name: CDC14-type phosphatase
def: "A protein that contains a conserved N-terminal copy of the DSPc (PF00782) domain. This domain contains a region that might contribute to substrate specificity and a catalytic region that encompasses the PTP signature motif. The C-terminal domain length varies among different members of this class." [PMID:20720150, PRO:CNA]
comment: Category=family.
is_a: PR:000000001 ! protein

[Term]
id: PR:000027623
name: tyrosine-protein phosphatase CDC14
def: "A CDC14-type phosphatase that is a translation product of the yeast CDC14 gene or a 1:1 ortholog thereof." [PMID:16085489, PMID:18951025, PRO:CNA]
comment: Category=gene. CDC14 is called CLP1 in fission yeast.
synonym: "CDC14" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027622 ! CDC14-type phosphatase

[Term]
id: PR:000027624
name: tyrosine-protein phosphatase CDC14 (fission yeast)
def: "A tyrosine-protein phosphatase CDC14 in fission yeast." [PMID:11683392, PomBase:MAH]
comment: Category=organism-gene. Flag=automatic.
synonym: "CDC fourteen-like phosphatase 1" EXACT []
synonym: "CLP1" RELATED []
synonym: "FLP1" RELATED []
synonym: "SPAC1782.09C" RELATED []
synonym: "Spom972h-CDC14" EXACT PRO-short-label [PRO:DNx]
synonym: "tyrosine-protein phosphatase CDC14 homolog" EXACT []
xref: UniProtKB:Q9P7H1

[Term]
id: PR:000027625
name: tyrosine-protein phosphatase CDC14 unmodified form
def: "A tyrosine-protein phosphatase CDC14 homolog that has not been subjected to any co- or post-translational modification." [PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "CDC14/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027626
name: tyrosine-protein phosphatase CDC14 unmodified form (fission yeast)
def: "A tyrosine-protein phosphatase CDC14 unmodified form in fission yeast." [PMID:16085489, PMID:18951025, PomBase:MAH]
comment: Category=organism-modification. Flag=automatic.
synonym: "clip1p unmodified" RELATED []
synonym: "flp1p unmodified" RELATED []
synonym: "Spom972h-CDC14/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027627
name: tyrosine-protein phosphatase CDC14 phosphorylated form
def: "A tyrosine-protein phosphatase CDC14 homolog that has been modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "CDC14 phosphorylated" BROAD []
synonym: "CDC14/PhosRes+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027628
name: tyrosine-protein phosphatase CDC14 phosphorylated 1
def: "A tyrosine-protein phosphatase CDC14 phosphorylated form that has been phosphorylated at the Ser residue within the RxxS motifs. Example: UniProtKB:Q9P7H1-1, Ser-396/Ser-408/Ser-467/Ser-468/Ser-493/Ser-513, MOD:00046." [PMID:16085489, PMID:18951025, PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "CDC14/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027627 ! tyrosine-protein phosphatase CDC14 phosphorylated form

[Term]
id: PR:000027629
name: tyrosine-protein phosphatase CDC14 phosphorylated 1 (fission yeast)
def: "A tyrosine-protein phosphatase CDC14 phosphorylated 1 in fission yeast. Phoshorylated in RxxS motifs by Sid2 family kinases. UniProtKB:Q9P7H1-1, Ser-396/Ser-408/Ser-467/Ser-468/Ser-493/Ser-513, MOD:00046." [PMID:16085489, PMID:18951025, PomBase:MAH]
comment: Category=organism-modification.
synonym: "clip1p phosphorylated" RELATED []
synonym: "flp1p phosphorylated" RELATED []
synonym: "Spom972h-CDC14/Phos:1" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027702
name: kinesin-like motor protein klp9/SPBC15D4.01c
def: "A protein that is a translation product of the fission yeast klp9 gene or a 1:1 ortholog thereof." [PomBase:SPBC15D4.01c, PRO:CNA]
comment: Category=gene. Flag=automatic.
synonym: "klp9" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000027703
name: kinesin-like motor protein klp9/SPBC15D4.01c (fission yeast)
def: "A kinesin-like motor protein klp9/SPBC15D4.01c that is encoded in the genome of fission yeast." [PomBase:SPBC15D4.01c, PRO:CNA]
comment: Category=organism-gene. Flag=automatic.
synonym: "klp9p" EXACT []
synonym: "Spom972h-klp9" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q1MTQ7

[Term]
id: PR:000027704
name: kinesin-like motor protein klp9/SPBC15D4.01c unmodified form
def: "A kinesin-like motor protein klp9/SPBC15D4.01c that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification.
synonym: "klp9/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027705
name: kinesin-like motor protein klp9/SPBC15D4.01c unmodified form (fission yeast)
def: "A kinesin-like motor protein klp9/SPBC15D4.01c unmodified form in fission yeast." [PMID:18257517, PMID:19686686, PomBase:MAH]
comment: Category=organism-modification.
synonym: "Spom972h-klp9/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027706
name: kinesin-like motor protein klp9/SPBC15D4.01c phosphorylated form
def: "A kinesin-like motor protein klp9/SPBC15D4.01c that has been post-translationally modified to include at least one phosphorylated residues." [PRO:CNA]
comment: Category=modification.
synonym: "klp9/PhosRes+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027702 ! kinesin-like motor protein klp9/SPBC15D4.01c

[Term]
id: PR:000027707
name: kinesin-like motor protein klp9/SPBC15D4.01c phosphorylated 1
def: "A kinesin-like motor protein klp9/SPBC15D4.01c phosphorylated form that has been phosphorylated on one or more of the CDC2-dependent phosphorylation sites at the C-terminal region." [PMID:18257517, PMID:19686686]
comment: Category=modification.
synonym: "klp9/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027706 ! kinesin-like motor protein klp9/SPBC15D4.01c phosphorylated form

[Term]
id: PR:000027708
name: kinesin-like motor protein klp9/SPBC15D4.01c phosphorylated 1 (fission yeast)
def: "A kinesin-like motor protein klp9/SPBC15D4.01c phosphorylated 1 in fission yeast. Phosphorylated by cdc2p during mitosis. Example: UniProtKB:Q1MTQ7-1, Ser-605, MOD:00046, and/or (Ser-611, MOD:00046, or Ser-613, MOD:00046)." [PMID:18257517, PMID:19686686, PomBase:MAH]
comment: Category=organism-modification. Note that there's a discrepancy between the two papers cited as to which residues are phosphorylated. The residues listed are those shown in the supplementary list of phosphopeptides in PMID:18257517. The text of PMID:19686686 reference back to PMID:18257517 but cites the incorrect residue numbers.
synonym: "Spom972h-klp9/Phos:1" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027713
name: ribonucleoside-diphosphate reductase small chain
def: "A ribonucleoside-diphosphate reductase class I, small subunit that is a translation product of the fission yeast suc22 gene or a 1:1 ortholog thereof." [PMID:12867051, PMID:20516199, PomBase:MAH]
comment: Category=gene. Flag=automatic.
synonym: "Ribonucleotide reductase small subunit" EXACT []
synonym: "suc22" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027717 ! ribonucleoside-diphosphate reductase class I, small subunit

[Term]
id: PR:000027714
name: ribonucleoside-diphosphate reductase small chain (fission yeast)
def: "A ribonucleoside-diphosphate reductase small chain that is encoded in the genome of fission yeast." [PMID:12867051, PMID:20516199, PomBase:MAH]
comment: Category=organism-gene. Flag=automatic.
synonym: "SPBC25D12.04" RELATED []
synonym: "Spom972h-suc22" EXACT PRO-short-label [PRO:DNx]
synonym: "SUC22" RELATED []
xref: UniProtKB:P36603

[Term]
id: PR:000027715
name: GTP-binding nuclear protein spi1
def: "A protein that is a translation product of the fission yeast spi1 gene or a 1:1 ortholog thereof." [PMID:18422602, PomBase:MAH]
comment: Category=gene. Flag=automatic.
synonym: "SPI1" RELATED []
synonym: "spi1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000027716
name: GTP-binding nuclear protein spi1 (fission yeast)
def: "A GTP-binding nuclear protein spi1 that is encoded in the genome of fission yeast." [PMID:18422602, PomBase:MAH]
comment: Category=organism-gene. Flag=automatic.
synonym: "SPBC1289.03C" RELATED []
synonym: "Spom972h-spi1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P28748

[Term]
id: PR:000027717
name: ribonucleoside-diphosphate reductase class I, small subunit
def: "A protein that is a stand-alone version of the Ribonucleotide reductase, small chain (PF00268) domain. This protein is the small subunit of the ribonucleotide reductase complex. The active subunit binds iron and contains an active site tyrosine radical." [PMID:15158709]
comment: Category=family.
synonym: "Ribonucleotide reductase small subunit" EXACT []
xref: PIRSF:PIRSF000355
is_a: PR:000000001 ! protein

[Term]
id: PR:000027718
name: ribonucleoside-diphosphate reductase large chain
def: "A protein that is a translation product of the fission yeast cdc22 gene or a 1:1 ortholog thereof." [PMID:14648198, PRO:CNA]
comment: Category=gene. Flag=automatic.
synonym: "CDC22" RELATED []
synonym: "cdc22" EXACT PRO-short-label [PRO:DNx]
synonym: "Ribonucleotide reductase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000027719
name: ribonucleoside-diphosphate reductase large chain (fission yeast)
def: "A ribonucleoside-diphosphate reductase large chain that is encoded in the genome of fission yeast." [PMID:14648198, PRO:CNA]
comment: Category=organism-gene. Flag=automatic.
synonym: "Spom972h-cdc22" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P36602

[Term]
id: PR:000027720
name: ribonucleoside-diphosphate reductase complex (fission yeast)
def: "A ribonucleoside-diphosphate reductase complex that is composed of two small (suc22) subunits and two large (cdc22) subunits." [PMID:20516199, PMID:8479429, PRO:CNA]
comment: Category=organism-complex. Requested by=PomBase.
synonym: "fission yeast ribonucleotide reductase complex" EXACT []
synonym: "fission yeast RNR" EXACT []
relationship: has_part PR:000027714 {cardinality="2"} ! ribonucleoside-diphosphate reductase small chain (fission yeast)
relationship: has_part PR:000027719 {cardinality="2"} ! ribonucleoside-diphosphate reductase large chain (fission yeast)

[Term]
id: PR:000027728
name: myosin type-2 heavy chain 1
def: "A protein that is a translation product of the fission yeast myo2 gene or a 1:1 ortholog thereof." [PMID:15184401, PRO:CNA]
comment: Category=gene. Flag=automatic.
synonym: "myo2" EXACT PRO-short-label [PRO:DNx]
synonym: "Myosin type II heavy chain 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000027729
name: myosin type-2 heavy chain 1 (fission yeast)
def: "A myosin type-2 heavy chain 1 that is encoded in the genome of fission yeast." [PMID:15184401, PRO:CNA]
comment: Category=organism-gene. Flag=automatic.
synonym: "SPCC645.05C" RELATED []
synonym: "Spom972h-myo2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9USI6

[Term]
id: PR:000027730
name: myosin type-2 heavy chain 1 unmodified form
def: "A myosin type-2 heavy chain 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "myo2/UnMod" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027728 ! myosin type-2 heavy chain 1

[Term]
id: PR:000027731
name: myosin type-2 heavy chain 1 unmodified form (fission yeast)
def: "A myosin type-2 heavy chain 1 unmodified form in fission yeast." [PMID:15184401, PomBase:MAH]
comment: Category=organism-modification. Flag=automatic.
synonym: "Spom972h-myo2/UnMod" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027732
name: myosin type-2 heavy chain 1 phosphorylated 1
def: "A myosin type-2 heavy chain 1 that has been phosphorylated on a Ser residue located in at the C-terminal region after the proline cluster. Example: UniProtKB:Q9USI6-1, Ser-1444, MOD:00046." [PMID:15184401, PomBase:MAH]
comment: Category=modification. Flag=automatic.
synonym: "myo2/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027728 ! myosin type-2 heavy chain 1

[Term]
id: PR:000027733
name: myosin type-2 heavy chain 1 phosphorylated 1 (fission yeast)
def: "A myosin type-2 heavy chain 1 phosphorylated 1 in fission yeast. UniProtKB:Q9USI6-1, Ser-1444, MOD:00046." [PMID:15184401, PomBase:MAH]
comment: Category=organism-modification. Flag=automatic.
synonym: "Spom972h-myo2/Phos:1" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000027897
name: AP-1-like transcription factor
def: "A protein that is a translation product of the fission yeast pap1 gene or a 1:1 ortholog thereof." [PMID:15165244, PMID:1899230, PomBase:MAH]
comment: Category=gene. Flag=automatic.
synonym: "CAF3" RELATED []
synonym: "Caffeine resistance protein 3" EXACT []
synonym: "pap1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000027898
name: AP-1-like transcription factor (fission yeast)
def: "An AP-1-like transcription factor that is encoded in the genome of fission yeast." [PMID:15165244, PMID:1899230, PomBase:MAH]
comment: Category=organism-gene. Flag=automatic.
synonym: "SPAC1783.07C" RELATED []
synonym: "Spom972h-pap1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q01663

[Term]
id: PR:000028932
name: peroxiredoxin tpx1
def: "A protein that is a translation product of the fission yeast tpx1 gene or a 1:1 ortholog thereof." [PMID:22245228, PRO:CNA]
comment: Category=gene. Requested by=PomBase.
synonym: "Peroxiredoxin tsa1" EXACT []
synonym: "Thioredoxin peroxidase" EXACT []
synonym: "TPX1" RELATED []
synonym: "tpx1" EXACT PRO-short-label [PRO:DNx]
synonym: "TSA1" RELATED []
is_a: PR:000000001 ! protein

[Term]
id: PR:000028933
name: peroxiredoxin tpx1 reduced form
def: "A peroxiredoxin tpx1 that its peroxidatic cysteine is in the reduced state." [PMID:22245228, PRO:CNA]
comment: Category=modification.
synonym: "tpx1/Red+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000028932 ! peroxiredoxin tpx1

[Term]
id: PR:000028934
name: peroxiredoxin tpx1 reduced form (fission yeast)
def: "A peroxiredoxin tpx1 reduced form in fission yeast." [PMID:22245228, PRO:CNA]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom972h-tpx1/Red+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000028935
name: peroxiredoxin tpx1 hyperoxidized form
def: "A peroxiredoxin tpx1 that its peroxidatic Cys residue is hyperoxidized." [PMID:22245228, PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "tpx1/HyperOx+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000028932 ! peroxiredoxin tpx1

[Term]
id: PR:000028936
name: peroxiredoxin tpx1 hyperoxidized form (fission yeast)
def: "A peroxiredoxin tpx1 hyperoxidized form in fission yeast. The oxidation occurs in under oxidative stress." [PMID:22245228, PRO:CNA]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom972h-tpx1/HyperOx+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000028937
name: AP-1-like transcription factor reduced form
def: "An AP-1-like transcription factor that its Cys residues are in the reduced state (as thiols)." [PRO:CNA]
comment: Category=modification.
synonym: "pap1/Red+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027897 ! AP-1-like transcription factor

[Term]
id: PR:000028938
name: AP-1-like transcription factor reduced form (fission yeast)
def: "An AP-1-like transcription factor reduced form in fission yeast." [PMID:22245228, PRO:CNA]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom972h-pap1/Red+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000028939
name: AP-1-like transcription factor oxidized form
def: "An AP-1-like transcription factor that regulatory Cys residues are in the oxidized state (forming disulfide bonds)." [PMID:22245228, PRO:CNA]
comment: Category=modification.
synonym: "pap1/Ox+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027897 ! AP-1-like transcription factor

[Term]
id: PR:000028940
name: AP-1-like transcription factor oxidized form (fission yeast)
def: "An AP-1-like transcription factor oxidized form in fission yeast. This form is produced under oxidative stress." [PMID:22245228, PRO:CNA]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom972h-pap1/Ox+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000028942
name: peptide methionine sulfoxide reductase reduced form
def: "A probable peptide methionine sulfoxide reductase that its regulatory Cys residues are in the reduced state." [PRO:CNA]
comment: Category=modification.
synonym: "MSRA/Red+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000010680 ! peptide methionine sulfoxide reductase

[Term]
id: PR:000028943
name: peptide methionine sulfoxide reductase reduced form (fission yeast)
def: "A peptide methionine sulfoxide reductase reduced form that is encoded in the genome of fission yeast." [PMID:22245228, PRO:CNA]
comment: Category=organism-sequence. Requested by=PomBase.

[Term]
id: PR:000028944
name: peptide methionine sulfoxide reductase oxidized form
def: "A peptide methionine sulfoxide reductase that regulatory Cys residues are in the oxidized state." [PMID:22245228, PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "MSRA/Ox+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000010680 ! peptide methionine sulfoxide reductase

[Term]
id: PR:000028945
name: peptide methionine sulfoxide reductase oxidized form (fission yeast)
def: "A peptide methionine sulfoxide reductase oxidized form in fission yeast." [PMID:22245228, PRO:CNA]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom972h-MSRA/Ox+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000028946
name: thioredoxin reduced form
def: "A thioredoxin that the Cys residues involved in dithiol-disulfide activity (CxxC motif) are in the reduced state." [PMID:22245228, PRO:CNA]
comment: Category=modification.
synonym: "Trx1-(SH)2" RELATED []
synonym: "TXN/Red+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000016853 ! thioredoxin

[Term]
id: PR:000028947
name: thioredoxin-1 reduced form (fission yeast)
def: "A thioredoxin reduced form in fission yeast. The reduced Cys are Cys-30 and Cys-33 in UniProtKB:O14463." [PMID:22245228, PRO:CNA]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom972h-TXN/Red+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000028948
name: thioredoxin oxidized form
def: "A thioredoxin that the Cys residues involved in dithiol-disulfide activity (CxxC motif) are forming disulfide bond." [PMID:22245228, PRO:CNA]
comment: Category=modification.
synonym: "Trx1-S2" RELATED []
synonym: "TXN/Ox+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000016853 ! thioredoxin

[Term]
id: PR:000028949
name: thioredoxin-1 oxidized form (fission yeast)
def: "A thioredoxin oxidized form in fission yeast. The disulfide bond involves Cys-30 and Cys-33 in UniProtKB:O14463." [PMID:22245228, PRO:CNA]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom972h-TXN/Ox+" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000028950
name: peroxiredoxin tpx1 complex
def: "A protein complex that its a dimer of peroxiredoxin tpx1 linked by an interchain disulfide bond." [PMID:22245228, PRO:CNA]
comment: Category=complex. Flag=automatic.

[Term]
id: PR:000028951
name: peroxiredoxin tpx1 complex (fission yeast)
def: "A peroxiredoxin tpx1 complex in fission yeast." [PMID:22245228, PRO:CNA]
comment: Category=organism-complex. Requested by=PomBase.
is_a: PR:000028950 ! peroxiredoxin tpx1 complex
relationship: has_part PR:000028936 {cardinality="2"} ! peroxiredoxin tpx1 hyperoxidized form (fission yeast)

[Term]
id: PR:000028988
name: sterol regulatory element-binding protein
def: "A protein that is a transmembrane protein where both N- and C-terminus are cytosolic, and the N-terminus contains a basic helix-loop-helix domain (PF00010) and functions as a transcription factor when cleaved off." [PMID:17303406]
comment: Category=family. Flag=automatic.
synonym: "bHLHd1" EXACT []
synonym: "class D basic helix-loop-helix protein 1" EXACT []
synonym: "SRE" RELATED []
synonym: "SREBF" RELATED []
synonym: "SREBP" RELATED []
synonym: "sterol regulatory element-binding transcription factor" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000028989
name: sre1-type sterol regulatory element-binding protein 1
def: "A sterol regulatory element-binding protein that is a translation product of the fission yeast sre1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene. Flag=automatic.
synonym: "SRE-1" RELATED []
synonym: "SRE1" RELATED []
synonym: "sre1" EXACT PRO-short-label [PRO:DNx]
synonym: "SREBP1" RELATED []
is_a: PR:000028988 ! sterol regulatory element-binding protein

[Term]
id: PR:000028990
name: sre1-type sterol regulatory element-binding protein 1 proteolytic cleavage product
def: "A proteolytic cleavage product that is derived from sre1-type sterol regulatory element-binding protein 1." [PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "sre1/ClvPrd" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000028991
name: sre1-type sterol regulatory element-binding protein 1 cleaved 1
def: "A sre1-type sterol regulatory element-binding protein 1 that has been processed by proteolytic cleavage yielding the N-terminal domain. Example: UniProtKB:Q9UUD1-1, 1-440." [PMID:22017871, PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "Processed sterol regulatory element-binding protein 1" RELATED []
synonym: "Sre1N" RELATED []
is_a: PR:000028990 ! sre1-type sterol regulatory element-binding protein 1 proteolytic cleavage product

[Term]
id: PR:000028992
name: Sre1N (fission yeast)
def: "A sre1-type sterol regulatory element-binding protein 1 cleaved 1 in fission yeast. This form is the N-terminal domain of the membrane protein sre1 that is cleaved off upon activation (e.g. by hypoxia). UniProtKB:Q9UUD1-1, 1-440." [PMID:22017871, PomBase:AL]
comment: Category=organism-modification.

[Term]
id: PR:000029043
name: fission yeast protein
def: "A protein that is encoded in the genome of fission yeast." [PRO:DAN]
synonym: "Spom972h protein" EXACT PRO-short-label []

[Term]
id: PR:000029916
name: mitotic checkpoint serine/threonine-protein kinase BUB1 unphosphorylated form
def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 which lacks phosphorylated residues." [PRO:CNA]
comment: Category=modification. Flag=automatic.
synonym: "BUB1/PhosRes-" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000035410
name: mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 5 (fission yeast)
def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 5 in fission yeast that represents the basal phosphorylated state observed during interphase and mitosis. Example: UniProtKB:O94751, MOD:00696." [PMID:12606573, PRO:KER]
comment: Category=organism-modification.
synonym: "Spom972h-BUB1/Phos:5" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000035411
name: mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 6 (fission yeast)
def: "A BUB1 CDK-consensus sites phosphorylated form in fission yeast. The exact combination of phosphorylated sites is not known but may involved Thr-340, Thr-423, Thr-455, and/or Ser-466 in UniProtKB:O94751. Phosphorylation occurs during Meiosis I or spindle disruption (tubulin mutant)." [PMID:12606573, PRO:KER]
comment: Category=organism-modification. Kinase=("CDC2"; UniProtKB:P04551).

[Term]
id: PR:000035413
name: BUB1 CDK-consensus sites phosphorylated form
def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 that is phosphorylated on CDK consensus sites (S/T-P-X-K/R) located in the middle region of BUB1." [PMID:12606573, PMID:16760428, PRO:KER]
comment: Category=modification.
synonym: "BUB1/PhosRes+" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000004854 ! mitotic checkpoint serine/threonine-protein kinase BUB1

[Term]
id: PR:000035414
name: mitotic checkpoint serine/threonine-protein kinase BUB1 unphosphorylated form (fission yeast)
def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 unphosphorylated form in fission yeast." [PRO:CNA]
comment: Category=organism-modification.
synonym: "Spom972h-BUB1/PhosRes-" EXACT PRO-short-label [PRO:DNx]

[Term]
id: PR:000035499
name: spindle assembly checkpoint component MAD3
def: "A protein that is a translation product of the Saccharomyces cerevisiae MAD3 gene or a 1:1 ortholog thereof. MAD3 is related to BUB1 and BUB1B, all of which contain the Mad3/BUB1 homology region 1 (PF00831), but MAD3 lacks the C-terminal Protein kinase domain (PF00069)." [PMID:15970700, PMID:22698286, PRO:KER]
comment: Category=gene. Flag=automatic.
synonym: "MAD3" EXACT PRO-short-label [PRO:DNx]
synonym: "Mitotic MAD3 protein" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000035566
name: BUB1:BUB3 complex
def: "A protein complex that is composed of BUB1 and BUB3. This complex is involved in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated." [PMID:10198256, PMID:11283619, PMID:15525512, PRO:KER]
comment: Category=complex.
synonym: "BUB1:BUB3 complex" EXACT []

[Term]
id: PR:000035569
name: BUB1:BUB3 complex (fission yeast)
def: "A BUB1:BUB3 complex whose components are encoded in the genome of fission yeast." [PMID:22660415, PRO:KER]
comment: Category=organism-complex.
synonym: "BUB1:BUB3 complex" RELATED []
is_a: PR:000035566 ! BUB1:BUB3 complex
relationship: has_part PR:000035570 {cardinality="1"} ! mitotic checkpoint serine/threonine-protein kinase BUB1 (fission yeast)
relationship: has_part PR:000035571 {cardinality="1"} ! mitotic checkpoint protein BUB3 (fission yeast)

[Term]
id: PR:000035570
name: mitotic checkpoint serine/threonine-protein kinase BUB1 (fission yeast)
def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 that is encoded in the genome of fission yeast." [PRO:CNA]
comment: Category=organism-gene. Flag=automatic.
synonym: "BUB1 (pombe)" EXACT []
synonym: "SPCC1322.12c" RELATED []
synonym: "Spom972h-BUB1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O94751

[Term]
id: PR:000035571
name: mitotic checkpoint protein BUB3 (fission yeast)
def: "A mitotic checkpoint protein BUB3 that is encoded in the genome of fission yeast." [PRO:KER]
comment: Category=organism-gene. Flag=automatic.
synonym: "SPAC23H3.08c" RELATED []
synonym: "Spom972h-BUB3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O42860

[Term]
id: PR:000035572
name: mitotic spindle assembly checkpoint protein MAD2 (fission yeast)
def: "A mitotic spindle assembly checkpoint protein MAD2A that is encoded in the genome of fission yeast." [PRO:KER]
comment: Category=organism-gene.
synonym: "Spom972h-MAD2L1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14417

[Term]
id: PR:000035573
name: spindle assembly checkpoint component MAD3 (fission yeast)
def: "A spindle assembly checkpoint component MAD3 encoded in the genome of fission yeast." [PMID:11909965, PRO:KER]
comment: Category=organism-gene. Flag=automatic.
synonym: "mitotic spindle checkpoint component mad3" EXACT []
synonym: "SPCC1795.01C" RELATED []
synonym: "SPCC895.02" RELATED []
synonym: "Spom972h-MAD3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O59767

[Term]
id: PR:000035574
name: MAD2:MAD3 complex (fission yeast)
def: "A MAD2:MAD3 complex whose components are encoded in the genome of fission yeast." [PMID:12676091, PRO:KER]
comment: Category=organism-complex.
synonym: "MAD2:MAD3 complex" RELATED []
relationship: has_part PR:000035572 {cardinality="1"} ! mitotic spindle assembly checkpoint protein MAD2 (fission yeast)
relationship: has_part PR:000035573 {cardinality="1"} ! spindle assembly checkpoint component MAD3 (fission yeast)

[Term]
id: PR:000035665
name: BUB1/BUB1B protein
def: "A protein that consists of a core domain composition consisting of a the Mad3/BUB1 homology region 1 (PF00831) and a C-terminal Protein kinase domain (PF00069). Members of this class are related to MAD3." [PMID:22698286, PRO:CNA]
comment: Category=family.
is_a: PR:000000001 ! protein

[Term]
id: PR:000035691
name: mitotic checkpoint serine/threonine-protein kinase BUB1 phosphorylated 5
def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 that has been post-translationally modified to include at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "BUB1 phosphorylated" RELATED []
synonym: "BUB1/Phos:5" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000004854 ! mitotic checkpoint serine/threonine-protein kinase BUB1