ID SPCC965 standard; DNA; FUN; 38090 BP. XX AC AL023590; XX SV AL023590.1 XX DT 16-MAY-1998 (Rel. 55, Created) DT 03-DEC-1999 (Rel. 61, Last updated, Version 4) XX DE S.pombe chromosome III cosmid c965. XX KW amino acid permease; car1 homologue; Glutathione S-transferase; KW major facilitator superfamily; putative alanine racemase; KW putative dipeptidase; putative flavanone 3-hydroxylase; KW putative metallopeptidase; KW putative mismatch-specific thymine dna glycosylase; putative nitrilase; KW putative potassium channel subunit; transcription factor; KW transport protein; vacuolar ATP synthase subunit; zinc finger protein. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-38090 RA Wood V., Rajandream M.A., Barrell B.G., Rieger M; RT ; RL Submitted (13-MAY-1998) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and Biotechnologische und molekularbiologische RL Forschung, Angelhofweg 39, D-69259 Wilhelmsfeld, Germany XX DR GOA; O59821; O59821. DR GOA; O59823; O59823. DR GOA; O59824; O59824. DR GOA; O59825; O59825. DR GOA; O59826; O59826. DR GOA; O59827; O59827. DR GOA; O59828; O59828. DR GOA; O59829; O59829. DR GOA; O59830; O59830. DR GOA; O59831; O59831. DR GOA; O59832; O59832. DR GOA; O59833; O59833. DR GOA; O59834; O59834. DR GOA; O60075; O60075. DR SPTREMBL; O59822; O59822. DR SPTREMBL; O59824; O59824. DR SPTREMBL; O59826; O59826. DR SPTREMBL; O59829; O59829. DR SPTREMBL; O59830; O59830. DR SPTREMBL; O59832; O59832. DR SPTREMBL; O59833; O59833. DR SPTREMBL; O59834; O59834. DR SPTREMBL; O60075; O60075. DR SWISS-PROT; O59821; CSL4_SCHPO. DR SWISS-PROT; O59823; VATD_SCHPO. DR SWISS-PROT; O59825; TDG_SCHPO. DR SWISS-PROT; O59827; GTH2_SCHPO. DR SWISS-PROT; O59828; ALR1_SCHPO. DR SWISS-PROT; O59831; YCUB_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 80% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c965 overlaps with c1494 at 3' end. XX FH Key Location/Qualifiers FH FT source 1..38090 FT /chromosome="III" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c965" FT /map="IIIR" FT misc_feature 1..3155 FT /note="nominal overlap with cosmid SPCC1840, EM:AL031179 S. FT pombe chromosome 3" FT CDS 663..1208 FT /db_xref="GOA:O59821" FT /db_xref="SWISS-PROT:O59821" FT /label=SPCC965.01 FT /note="SPCC965.01, 181aa, SIMILARITY: S. cerevisiae, FT CSL4_YEAST, 3'-5' EXORIBONUCLEASE CSL4, (292 aa), fasta FT scores, opt:348, E(): 4.1e-16, (40.6% identity in 160 aa FT overlap)" FT /gene="SPCC965.01" FT /gene="SPCC1840.11" FT /product="putative exoribonuclease" FT /protein_id="CAA19061.2" FT /translation="MNLVLPGQVVARGAPNGEGTVKRGDYIISTRTGIFDPEKNSVTYP FT RKVEETAVLPNVGSIVLARVSRINARQATVNISVVDDVCTKDEFQGVIHVQDIRATEKN FT KVKVQNSFRPGDIVRALVISLGDGSSYFLTTARNDLGVIFAQSSETGEQMFPVDYQHMQ FT TKSGYTEMRKCAKPILDE" FT CDS join(2942..3242,3357..5431) FT /db_xref="SPTREMBL:O59822" FT /label=SPCC965.02 FT /note="SPCC965.02, S. pombe sp4 homologue len:791aa, FT similar eg. to S. pombe, O14031,hy pothetical 96.3 kd FT protein., (851aa), fasta scores, opt:148 7, E():0, (35.7% FT identity in 719 aa overlap), also similar to YJL212C, FT YJV2_YEAST, P40897, strong similarity to S.pombe isp4 FT protein, (799aa), fasta scores, opt:1453, E():0,(3 1.8% FT identity in 758 aa overlap)" FT /gene="SPCC965.02" FT /product="hypothetical protein" FT /gene="SPCC1840.12" FT /protein_id="CAA19062.1" FT /translation="MKTPKFITYVTRGFKGLESKSVENNKDHIVENSSPIASKFHEFDE FT QKKSFEIINYAGHEKFVDDITERESSVPGNAVYDITVRDIDAIVPVTDDVDIPASTFRM FT WILAFGLATVIAGVDAFFLMRYPSVSIAAIVALLVAYPLGQLWYYIIPQWEIKLPRGIR FT VSLNPGRFNRKEHACLYIFVNICVSAKLVNTLIIEQIKFFGVNIGIGRAILFNLCSYLS FT SFGWSGLALPILVYPPTLIWPSVLSSCALFKIFHDNDNTKACNWTISRLRYFFIVFVAS FT FIWYWFPDLIFPALSSLGAWISWCKPSSAVLSQIFGVKTGLGLFPLTLDWAQISSLSNP FT LITPWWATCCIFTSFVFWIWIVLPGLYYQNYWQVAHFPIMTNSIYTVSGKSYDAQKVVD FT SKWELVTQKYQEYSPVMLPIAFIINIALSLGAFSSMMISFFLRFPTDVIQPICHVFKYS FT DIHTKLLKKYKRVHWGFYLASIIVSLGLGFAFTEGWHDIQIRSYGFVVSMVIGAALYIP FT LSLIESRSSFTISMQAFFEIVAAFWFNGQPMALLYFYSFGFGTLQHAMHMTQSAKIGHY FT MKVPPRLVAALLFTSGIWSSLVNSAVTGWIMYHVRDVCTSNAENNMTCRSPKTQFNSHL FT IWGLVGNHIFSSDGRYSFVMWFFLVGAVVSVVVYLLQISFPKSSWKHVNPALLLGGAAQ FT IPSVTGINYSTWAAVAFCFNYLIRRGYYSWWKKYNLITAAAMDCGVAIAGLFIYFCVVY FT TGGSSNFSWWGTTVSSAGCDKKGCAHLSVSDISKPSGW" FT misc_feature 3243..3248 FT /note="gtaagt, splice donor sequence" FT misc_feature 3334..3356 FT /note="ttaacttctcactttctttgtag, splice branch and acceptor" FT CDS join(6403..6443,6484..6601,6861..7559) FT /db_xref="GOA:O59823" FT /db_xref="SWISS-PROT:O59823" FT /label=SPCC965.03 FT /note="SPCC965.03, vacuolar ATP synthase subunit, len:285aa FT , similar eg. to YEL051W, VATD_YEAST, P32610, vacuolar ATPs FT ynthase subunit d, (256aa), fasta scores, opt:913, E():0,(6 FT 2.9% identity in 221 aa overlap)" FT /gene="SPCC965.03" FT /product="vacuolar ATP synthase subunit D" FT /protein_id="CAA19063.1" FT /translation="MASKQRENVFPTRMTLTTMKTRLKGAQTGHSLLKRKSEALKKRFR FT EIVVNIEQAKQKMGRVMQIAAFSMAEVGFAMGNNINFEIQQSVKQPRLRVRSKQENISG FT VFLPTFEMNLDESIDDFQLTGLGKGGQQIQKARQVYEKAVETLVQLASYQSAFVLLGDV FT LQMTNRRVNSIEHIIIPRLENTIKYIESELEELEREDFTRLKKVQKTKENAEKADSVTK FT EEHQGGSNTLQQTKDVGGAIAPAAEVGKEVINEVENSKDDTYSLPSTSTDDEEENDSDE FT EVIF" FT misc_feature 6442..7044 FT /note="Pfam match to entry PF01813 ATP-synt_D, ATP synthase FT subunit D, score 360.50, E-value 1.8e-104" FT misc_feature 6444..6449 FT /note="gtacgc, splice donor sequence" FT misc_feature 6471..6483 FT /note="ctaattttattag, splice branch and acceptor" FT misc_feature 6602..6607 FT /note="gtaagt, splice donor sequence" FT misc_feature 6843..6860 FT /note="ctaatgatatcttgatag, splice branch and acceptor" FT CDS join(complement(10525..10557),complement(8327..10423)) FT /db_xref="GOA:O59824" FT /db_xref="SPTREMBL:O59824" FT /label=SPCC965.04c FT /note="SPCC965.04c, len:709aa, similar eg. to YPR024W, FT YME1_YEAST, P32795, protease of theS EC18/CDC48/PAS1 family FT of ATPases (AAA) , (747aa), fasta sc ores, opt:1739, E():0, FT (47.8% identity in 651 aa overlap),a lso similar eg. to E. FT coli, FTSH_ECOLI, P28691, cell divisi on protein ftsh; FT atp-dependent zinc metallopeptidase, (644a a), fasta FT scores, opt:1361, E():0, (44.5% identity in 542aa overlap)" FT /gene="SPCC965.04c" FT /product="putative metallopeptidase" FT /protein_id="CAA19064.1" FT /translation="MSRVLHPIFLFGKTSFLYSGCSKFGGRLFNNSIVHGWLRTRSYAL FT ASGLHPLRKQKLAHFEDLANANMSDPYMQAKLYKELADNFPEAIISRYETQGVARNSAC FT DRYYQEALRKKSWSRSLSNNISLSQSSSSPATSSFSDPKAFSAGVPKFTSDTSSTVSST FT PSLNHSLQNSMPPSTPTPPPVWAPTIVSSALGTSSKTPVYVVVDEPRFTKFFRIFKFIA FT GLSVASYFVLLGMSIFAETSGLNNIMTNTTEQEPMEERAINVRFSDVQGVDEAKEELEE FT IVDFLRDPTHFTRLGGKLPRGVLLTGPPGTGKTMLARAVAGEANVPFFFMSGSQFDEMY FT VGVGAKRVRELFAAARKQAPSIIFIDELDAIGQKRNARDAAHMRQTLNQLLVDLDGFSK FT NEDLAHPVVFIGATNFPESLDPALTRPGRFDRHIHVPLPDVRGRLAILLQHTRHVPLGK FT DVDLSIIARGTSGFAGADLANLINQAAVYASKNLSTAVSMRDLEWSKDRILMGAERKSA FT FITPENKLMTAYHEGGHALVALFTKNAMRPYKATIMPRGSSLGMTISLPDMDKDSWTRE FT EYLAMLDVTMGGRAAEELLYGKDKITSGAHNDIDKATQVARRMVTEFGMSDRIGPVSLE FT AEMDNLSPATRALVESEIKSLLEASYERSLSLLKSHKKELDALATALVDYEFLTAEEMN FT RVVKGDRDLLRNKLS" FT misc_feature complement(8369..8971) FT /note="Match to PF01434 Peptidase_M41, Peptidase family M41 FT Score 409.28" FT misc_feature complement(8993..9553) FT /note="Match to PF00004 AAA, ATPases associated with FT various cellular activities (AAA) Score 305.14" FT misc_feature complement(9088..9654) FT /note="Pfam match to entry AAA PF00004, ATPases associatedw FT ith various cellular activities (AAA)" FT misc_feature complement(9515..9538) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(10424..10445) FT /note="ctaactcattacttgacgatag, splice branch and acceptor" FT misc_feature complement(10519..10524) FT /note="gtaagt, splice donor sequence" FT CDS complement(12334..13311) FT /db_xref="GOA:O59825" FT /db_xref="SWISS-PROT:O59825" FT /label=SPCC965.05c FT /note="SPCC965.05c, len:325aa, similar eg. to H. sapiens, FT Q13569, g/t mismatch-specific thymine dna glycosylase, FT (410aa), fasta scores, opt:362, E():2.2e-10, (35.8% ide FT ntity in 179 aa overlap)" FT /gene="SPCC965.05c" FT /product="putative mismatch-specific thymine dna FT glycosylase" FT /protein_id="CAA19065.1" FT /translation="MNDIETRDTGTKNDNSSEFNLSVKSHKRKRSFDDENLELEESREE FT TSGGILKKAKTQSFSESLERFRFAHAGSNNEYRKTDVVKNSDTDNGLLKSAVETITLEN FT GLRNRRVNVTKKSTLKASVKKSTLKKKNEVDPALLQGVPDYICENPYAIIVGLNPGITS FT SLKGHAFASPSNRFWKMLNKSKLLEGNAEFTYLNDKDLPAHGLGITNLCARPSSSGADL FT RKEEMQDGARILYEKVKRYRPQVGLFISGKGIWEEMYKMLTGKKLPKTFVFGWQPEKFG FT DANVFVGISSSGRAAGYSDEKKQNLWNLFAEEVNRHREIVKHAV" FT CDS 14617..15651 FT /db_xref="GOA:O59826" FT /db_xref="SPTREMBL:O59826" FT /label=SPCC965.06 FT /note="SPCC965.06, len: 344aa, similar eg. to , E1249836, FT potassium channel beta subunit fragment, (328aa), fasta FT scores, opt:1033, E():0, (47 .4% identity in 325 aa FT overlap) also similar eg. to O23016 T1G11.6 PROTEIN, (328 FT aa), fasta scores, opt:1033, E():0, (48.9% identity in 325 FT aa overlap)" FT /gene="SPCC965.06" FT /product="putative potassium channel subunit" FT /protein_id="CAA19066.1" FT /translation="MASATTHFQPKNVPFRFLGRSGLKVSAFSLGGWLTYGNEGYDVEH FT TKNCLKQAWDLGINTFDTAEIYSNGNSETVMGKAIKELGWDRSEYVITTKVFFGAGTKL FT PNTTGLSRKHIIEGLNASLKRLGLPYVDVIMAHRPDPSVPMEEVVRAFTQLIQDGKAFY FT WGTSEWSAFEIEHAHHIATKYNLIAPVADQPQYNYLTRDHFEKDLLPLQQIYGYGATVW FT SPLKSGILTGKYNDGIPEGSRLSTTFTSLAGQLQTPEGKTQLDQVRQISKIAEQIGATP FT SQLALAWTLKNPYVSTTILGASKPEQIVENVKAVEFIDKLTPEILKKIDEILNFTPLEI FT QYRR" FT CDS complement(16705..17397) FT /db_xref="GOA:O59827" FT /db_xref="SWISS-PROT:O59827" FT /label=SPCC965.07c FT /note="SPCC965.07c, len:230aa, similar eg. (to the terminal FT 2/3 of) to YNL229C, URE2_YEAST, P23202, nitrogen catabolite FT repression regulator, (354aa),fasta scores, opt:433, E():0, FT (36.8% identity in 247 aa over lap), also similar eg. FT (along full length) to B. cepacia, Q 45073, hypothetical FT 23.3 kd protein, (205aa), fasta scores, opt:331, FT E():4.3e-18, (35.7% identity in 210 aa overlap)" FT /gene="SPCC965.07c" FT /product="Glutathione S-transferase" FT /protein_id="CAA19067.1" FT /translation="MAHFTLYSHAGGPNPWKVVLALKELNLSYEQIFYDFQKGEQKCKE FT HLALNPNGRVPTLVDHKNNDYTIWESDAILIYLADKYDTDRKISLSFDDPEYYKLIQYL FT FFQASGQGVIWGQAGWFNFFHHEPVVSAVTRYRNEIKRVLGVLEDILKDRDYLVANKYT FT IADLSFIPWNYNLGGLFGEGKFSFKEEVPQLDFEKEFPKAYAWNQRLLARPAVKATFEE FT LAKAKEQH" FT misc_feature complement(16756..17385) FT /note="Match to PF00043 GST, Glutathione S-transferases. FT Score 128.35" FT misc_feature complement(16756..17397) FT /note="Pfam match to entry gluts PF00043, Glutathione S-tra FT nsferases" FT CDS complement(18893..20020) FT /db_xref="GOA:O59828" FT /db_xref="SWISS-PROT:O59828" FT /label=SPCC965.08c FT /note="SPCC965.08c, len:375aa, s imilar eg. to E. coli, FT ALR1_ECOLI, P29743, alanine racemase , (359aa), fasta FT scores, opt:858, E():0, (43.9% identity in 376 aa overlap), FT also similar eg. to S. typhimurium, ALR1_S ALTY, P06655, FT alanine racemase, (359aa), fasta scores, opt: 823, E():0, FT (43.1% identity in 376 aa overlap)" FT /gene="SPCC965.08c" FT /product="putative alanine racemase" FT /protein_id="CAA19068.1" FT /translation="MRGAKSVIDLHAIAHNYNVAKQMMLQKNPSGHVLAIVKANAYGHG FT AVQVARFLLKHCSSIDGFGVSSIEEALELRHGGIYNKIVLLEGFFTEEDELKLIDDYNF FT SIIIHSEDQVNSFIKYPFNRPVEIWLKLDSGMNRLGFTPSQFMKFYNLLSNNKNVSNIG FT KITHFAFADMLENPEHTLKQWDIFEKSVAHLPGPLSAGGSAIILGWLNTVCTDWLRAGI FT MLYGISPFLSKNKDSKTPESVNIKPAMKLVSTIISVKHVDKGQPIGYGGRYVATRDMKL FT GVVAMGYGDGFPRQVKDGCPVLVNGVKAPIVGRVSMDMLTVDLSDIPDVKPGDEVIFWG FT TPELTVADIAKYCSDTSPYELVTKLTRRVPLQYTY" FT misc_feature complement(18902..19927) FT /note="Match to PF00842 Ala_racemase, Alanine racemase FT Score 360.71" FT CDS 22026..22844 FT /db_xref="GOA:O59829" FT /db_xref="SPTREMBL:O59829" FT /label=SPCC965.09 FT /note="SPCC965.09, putative nitrilase, len:272aa, similar FT eg . to YLR351C, YL85_YEAST, P49954, nitrilase, (291aa), FT fastas cores, opt:236, E():5.9e-23, (28.8% identity in 281 FT aa over lap)" FT /gene="SPCC965.09" FT /product="hypothetical protein" FT /protein_id="CAA19069.1" FT /translation="MKANIACVQMAPKVCDVKHNLQKMSSYVHEVMESNPSTNLILFPE FT LITSGYECGNTFTQIAEIAGEGPSFKTMSNLAAKYHVNIIYGFPEKEEKQSNIIYNSCI FT YITENGNLGGVYRKVHLFDTERKHFKKGSDFPIFETSFGKLGVMICWDTAFPEVARIHA FT LNGADLLVVATNWENPYSDDWDLVTKARAFENCIPLVAANRVGTDEKLSFFGHSKIIGP FT TGKVIKALDEEKEGVISYTVDLDDAKPLRKNYYTFFEDRMPDLYKRLLSP" FT CDS 23879..25456 FT /db_xref="GOA:O59830" FT /db_xref="SPTREMBL:O59830" FT /label=SPCC965.10 FT /note="SPCC965.10, len:525aa, similar eg. to YDR034C, FT LY14_YEAST, P4097 1, transcriptional activator of lysine FT pathway genes, (790a a), fasta scores, opt:160, FT E():1.1e-09, (22.3% identity in4 94 aa overlap)" FT /gene="SPCC965.10" FT /product="putative transcriptional activator" FT /protein_id="CAA19070.1" FT /translation="MTSTSHFVASTVKKPRSRYGCLICRSMRKKCDEVHPQCGRCLKAG FT KQCIWKQPGTERKNKTKWRKAMQNNSIPIQDLADDFELDFPDTLDLTNPDALPVLGESI FT VNPISLPVDVASPFLPSECYPSKVELPYFPLLSKPNTLLSLLNDEEISCCEYYCYSVAP FT ITTILPGQPNFLPQLLLPMALHEESVLYSLVASGYRLKYGNDNSLALQKSKVFVNRALL FT TLPERRSLNLSKSEFVVSLACYILLVYTEIAFADTTEWATYFLNAYNMINKMGGFKILK FT ECSSEGKLLAECFAYFDILASQSNLNGTYYSISDYTDVYGVDELQLFESLENCIKPLVL FT IIGDIINLLVESRRAGFDDLQHTLNIYEKSQTIEGKIWSCVPQYEDMKSNKLDSEKSEP FT LQLFKLYKTTTEMYLRQVISRMPPVSLEMQVLLHKQTQLIDLLLESSLRNSLSFPMLIA FT GLNAATDLQRTNFKNRVNCLCQNYTIGSLKKVWIVVQEIWKMNQNGNICIDWYEVVQKF FT GWRLNTGV" FT misc_feature 23933..24037 FT /note="Match to PF00172 Zn_clus, Fungal Zn(2)-Cys(6) FT binuclear cluster domain Score 41.02" FT misc_feature 23933..24049 FT /note="Pfam match to entry Zn_clus PF00172, Fungal Zn(2)-Cy FT s(6) binuclear cluster domain" FT misc_feature 23936..24022 FT /note="PS00463 Fungal Zn(2)-Cys(6) binuclear cluster domain FT signature" FT CDS complement(25467..27080) FT /db_xref="GOA:O59831" FT /db_xref="SWISS-PROT:O59831" FT /label=SPCC965.11c FT /note="SPCC965.11c, len:537aa, simila r eg. to YFL055W, FT AGP3_YEAST, P43548, amino acid permease,( 558aa), fasta FT scores, opt:1592, E():0, (46.2% identity in52 2 aa FT overlap)" FT /gene="SPCC965.11c" FT /product="amino acid permease" FT /protein_id="CAA19071.1" FT /translation="MEAAPSEKVPAKKLSSSENLDIGVSEVVTVDAAENNSNGIKRGLK FT TRHVSMMALAGIIGPGVFIGMGSALHIGGPVGLIVGFAIVSIVVFGVMLSIGEFNSLFD FT FNFNTHAARWVDPAFGAAIGWNYVIVWLTNIAAEYTSLTSILQYWGPHVPSYGFFLIFW FT GFFTCYQMLGVSVFGESEYILAFIKLLFITGFYIFAIIYAAGGIPHHKPPNLFKEMPLA FT HGFGGIVSAFVYAGVFFSGVESVSMTAAESKNPKKAIPLAVRQTFWRILYVYFGISISY FT GITVAWNDPNLSSGSKTLKSPMTIAIMNAGWNHAGDFVNAVILITCLSSINSGIYIGSR FT SLYNLAKDGMAPKIFKRVDKRGVPWVAVHSVHLFGFLSIMNYSTGAVKAYGYIINLAGV FT SAFIVWTAIIFVHFRFRRGWVKQGYALSDLPFKSPLYPFPQLIGFVIGIILTLVQGWTV FT FKPFAAGDFVDAYILLPLFFVIWLSYKFIKKTKWVSYEDMDFINGRRVIEPTYSNEQSS FT DKETEDGKKTSFWNRVWKEV" FT misc_feature complement(25614..26960) FT /note="Match to PF00324 aa_permeases, Amino acid permease FT Score 617.06" FT misc_feature complement(25614..26963) FT /note="Pfam match to entry aa_permeases PF00324, Amino acid FT permeases" FT intron 27323..27378 FT /note="confirmed in 5'UTR" FT CDS 27622..28872 FT /db_xref="GOA:O59832" FT /db_xref="SPTREMBL:O59832" FT /label=SPCC965.12 FT /note="SPCC965.12, len:416aa, similar eg. to S. pombe, FT O14124, dipeptidase, (409aa), fasta score s, opt:978, FT E():0, (46.8% identity in 361 aa overlap), also similar eg. FT to R. norvegicus, MDP1_RAT, P31430, microsoma l FT dipeptidase precursor, (410aa), fasta scores, opt:949, E( FT ):0, (43.6% identity in 376 aa overlap)" FT /gene="SPCC965.12" FT /product="putative dipeptidase" FT /protein_id="CAA19072.1" FT /translation="MTVDLREEKELAQQRFKEICKHAKIVDTHNDFPYLLRVQLRNKLQ FT LAEFDFENGLTSHTDLVKMRQGQVGVQFFSCFIECKNPNYLYQDFDTPTTVVRDTLEQI FT DVTRRLVCKYNNDLKFVDCADDAIAAFRNNGKIAIALGVEGLHQVDTSLAVLRQYYSLG FT VRYITLTHNCDNPFATAASSITGGLPDRGLSAYGIECIFEMNRLGMMVDLSHVSHRTMH FT DALDVTKAPVIFSHSSAYTLTEHERNVRDDVLERLKTNGGVVQVNFYQDFIRKPGSDRA FT TIDDAADHILHIIKVAGWEHVGLGSDFDGIPQGPKGLEDVSKYPDLICKIIERTNATNE FT QIEGLMGLNVLRVWKKTELVALQLSKKLEPIESSWSGRKWEFYSYAKEFPELFPDAYKL FT NEKSTVWNYDQPLNIEK" FT misc_feature 27643..28818 FT /note="Match to PF01244 Renal_dipeptase, Renal dipeptidase FT Score 323.89" FT rRNA complement(29452..29649) FT /note="5s rrna gene" FT misc_feature complement(29650..33810) FT /note="low complexity gene free region" FT CDS 33810..35423 FT /db_xref="GOA:O59833" FT /db_xref="SPTREMBL:O59833" FT /label=SPCC965.13 FT /note="SPCC965.13, len:537aa, similar eg.to S. pombe, FT CAR1_SCHPO, P33532, amiloride resistance protein ; car1, FT (526aa), fasta scores, opt:1360, E():0, (43.3% iden tity in FT 487 aa overlap), contains PS00216 Sugar transport p roteins FT signature 1)" FT /gene="SPCC965.13" FT /product="putative MFS amorilide transporter" FT /protein_id="CAA19073.1" FT /translation="MSILNVIRSHHDVEPQNVEEEPPLTGQTIVTEDKLETSAKDKKHE FT SPSMSEDEEGSVENVDAWDLTKALMSIDPNHPAHPHKWPLWKKLFVATVYTFLEVYVIW FT SSTACINFFDIYQTNWHCSIQVSYLVQSLFIVGNAFGPMLLGPMSDIFGRKWVYVGSLI FT LYIIFQIPQALAYNLPMMAINSAIAGAFGSSALANVASSMCDIFTPETVGFGISLFVWG FT ANAGASIGSPIGEALYDHWRWFYWMNMIVGGFFVILCVLCPETLPVINIMNYSSTTGEK FT TVQVSTLAKAKSAVVRTKFVLSTAFKLLCTEPIIMALGLYNGFAYGLIFLYLDGLFPVF FT VDNYKMGYMGANLTYLNFLVGVTIVVMLQPIQNWLYRWDKRRHGGVARPEARFLISLLT FT VWFFPAGLFWFAFTSDGRISWVSPLIAGGVLGVGDPQLWLAMINYITDSYPSVAGSAIA FT AFTLPSFAIAAVLVHLGIIMFDNMTTTWAMATLAFISLSLVATIYVIYFFGHLIRKHSR FT LAVTQQALQEAHDAKVLPEV" FT misc_feature 34242..34292 FT /note="PS00216 Sugar transport proteins signature 1" FT CDS 36132..36620 FT /db_xref="GOA:O59834" FT /db_xref="SPTREMBL:O59834" FT /label=SPCC965.14c FT /note="SPCC965.14c, len:161aa" FT /gene="SPCC965.14c" FT /product="putative Cytidine and deoxycytidylate deaminase FT zinc-binding protein" FT /protein_id="CAA19074.1" FT /translation="MSSTELSEKDLAYLREAIKVSQQARDEGQHPFGCIIVDENDNVIM FT SAGNRVPDGDVTQHAETRAVGLITKTRRDLEKCTLYTSTEPCAMCSGAIFWSGIRRMIF FT GLSNENLIKLTQKSGECPPLYINSRDILGAASHPIEVVGPYIEDEAIIPHKGFWDGGR" FT misc_feature 36306..36413 FT /note="Match to PF00383 dCMP_cyt_deam, Cytidine and FT deoxycytidylate deaminase zinc-binding region Score 31.11" FT misc_feature 36725..38090 FT /note="nominal overlap with cosmid SPCC1494, EM:AL023776 FT S.pombe chromosome 3" FT CDS 37772..38090 FT /db_xref="GOA:O60075" FT /db_xref="SPTREMBL:O60075" FT /label=SPCC965.15 FT /note="SPCC965.15, len:<106aa, similar eg . to P. FT americana, Q40754, flavanone 3-hydroxylase, (369aa) , fasta FT scores, opt:175, E():7.2e-10, (29.0% identity in 10 7 aa FT overlap)" FT /partial FT /gene="SPCC965.15" FT /gene="SPCC1494.01" FT /product="Iron/Ascorbate oxidoreductase family protein" FT /protein_id="CAA19075.1" FT /translation="MGSLEVPCIDLSENDTSIVVKELLDACKNWGFVSLKNHGIPLDEI FT DRTFKLADKFFDIPVEEKQKYLFKGGRLHSGYTGHFGEKLDMEHQSRGDLKESYDLAGF FT PD" XX SQ Sequence 38090 BP; 11877 A; 6860 C; 6789 G; 12564 T; 0 other; gatcacaaac tcatttttct tcttattttg tgggtttcat ctttcttaaa tgattcttgg 60 gaacgttaac atacctttgt ttccttaatt tgatttatgc actttgattt tgaaatttgt 120 ggtcaacttg tttaaagact ttatatttat cattgatttt tgttattata tggaaaaaaa 180 catcacaatt tatatcattt actgtgcata acattcttca tttttgctgt cacgcttaat 240 gtttacactg gaaaatttct ctaccttgag aaatatttca gcatcatggt ccaatttaca 300 aagatcattt gagttaaaca aaaaaaatga tttattatat ttgctgctca tatttttttt 360 ttagtgattt tttattttgg catcgttttg tgaacttact ttccaagctt tgggattatc 420 aagaaaaaat ttttgttgaa agaagagcag aaaaactgtt tgataattaa atgcctttgc 480 aatttcattt tctcaattta gcaaaataaa ctgaaatttc tgcagcagtg actttaggtt 540 acattgtaac ctacagttta caacgacctt tgtgcttaca gcaacttttt ttcaattaat 600 tttttacagc catacaaaac ggacttgatt cctttatttt tagtttatta aagccgttaa 660 atatgaattt ggttctccct ggacaggtgg tcgcgagagg ggctcctaac ggtgaaggaa 720 cggtaaagag aggagattat attatttcca cacgaactgg catctttgat ccagagaaaa 780 attctgtaac gtacccaaga aaagttgaag agacagccgt tttacctaat gtcggatcta 840 ttgttttagc tcgcgtcagc aggatcaatg ctcgtcaagc aactgtaaac atctcagtcg 900 ttgacgatgt ctgcaccaaa gatgaatttc aaggggtaat acatgtgcag gatattagag 960 ctactgagaa aaataaagtc aaagtgcaaa attcattccg accgggtgat attgtcagag 1020 cacttgtaat ttcacttgga gacggctctt cgtacttttt aacaacagct cgaaatgatc 1080 ttggtgtgat ttttgctcag tctagtgaaa caggagagca aatgtttccg gtggattatc 1140 agcatatgca aacaaaatca ggatatacgg aaatgcgtaa atgtgctaaa cctatattag 1200 acgaataaaa tgaggggata aaattgcttt gttttgatat aacctgatag ttttttttcc 1260 ctctcggttc gttctttcct aacaaaaaaa aaattctgaa attgttagag attttatgat 1320 acgaatatac ggaacacgga taaaaataat attgaatata gaaatattgg aagttcatta 1380 gaatgatgat tgaggtgact tgctgtcgaa accgatatca ttttcaatta gaagtcaaat 1440 gtatagtttt ataagatata gagaaccttt gtaattcaac tgaacggaca ggagctctga 1500 agtttcttaa agttatttac ttaatggaac tgaattggtc ggttgtttat aaactctaat 1560 tcattaacaa aaacatgaat aaggagtttc tagcaataat atgtgttatg tttacaactt 1620 tctaagaagg ttactgtatt aagttatttt gtgtaattta atatcgagga ttgcaccttt 1680 cattggaggc tgtgatatcc tgaaataaca tttatgatca cagatttaag gatgaagtat 1740 ttaatgacat gaaaattagt attcgtacac ctctcagtaa cttttcaaaa ctactttcag 1800 tttttacatt aagggattgg atgtactttt tatacacagt tttataaaat actaggttgt 1860 ctctaaacat caagtatcat ctcaatcttt actttcggcc attagactga tatattttat 1920 atcaattaat tagtagacaa ctgtttccag attctcatat aagcacgaga gcttctattc 1980 tacccgtctt ttccgtatat agctgtcatg actcattaag ctactccagc gtgagactat 2040 caaatttaat ctcttcatcc ctaatatttg tttgtaaata cttataattg caaaatattc 2100 cattaccatg acatcaaata gaggattcta aatccaattc gcaggtacac tgactttaat 2160 ggattctggg ctagttccat aaaaagggat tgaaaggttt tattttccat atgataatag 2220 gtttcaataa tcagttcgac aaaaacatct ttcattagca tacttattac ctcaaatagt 2280 cgatgtttaa ctatatcaga tgactatctt atcagattat tcttcaatct taagcttagg 2340 atttctataa aagttggtta caaatacatc tctttatgac gaaaatttac cgaaaaaagt 2400 acatctggag tcgctcattc catcttagat aatttgttcg agaagcttat aattccggat 2460 cgttttgtca gtaactgtat gatgggctga gattgtcttc taatacgctg tcttcactgg 2520 aatgcaagag cgcaatggtt ttatatctac tagctttgtg attcggcgag agttaagatg 2580 ttgttccgaa attagccata tggtgagtaa accgtgctgc aactaatctt aacagatcaa 2640 ttctcactat ttgaatttgg gaaggcttct aggcagcaac ttccagacca tcgtaagtcg 2700 gcttgtcgct gtgcagagta taaacgtgat gaaaaagatg tggagataat tcgtaacttt 2760 gaactcatgc acaggttttt attattcgtt gttggtatcc tttagaaacc cttgcgatta 2820 ctccagcttg cacatcaatc gtataaatat agtcttattt ctttctccaa agctgctgat 2880 ctgataaaga ttactttgat caaattggtc ctgggttaag taacaatttc atttttgaag 2940 gatgaaaact ccaaaattta tcacttacgt tactcgtggt ttcaaaggac ttgaatcgaa 3000 aagcgttgaa aacaacaaag accatatcgt agaaaactcg agccctatcg cctcgaaatt 3060 tcatgaattc gatgagcaaa agaaatcttt tgaaatcata aattatgctg gtcacgaaaa 3120 gtttgttgac gacattactg aaagagaatc ctcagtacca ggaaatgctg tttacgatat 3180 taccgtcagg gacattgatg caattgtacc tgtaacggac gatgttgata tacccgcatc 3240 gagtaagtca aagctaatcc tactttttcc tttttttttt ttttttagaa gctgtcattc 3300 aggatttcca ttactatccc ttcaaccttg atattaactt ctcactttct ttgtagcttt 3360 caggatgtgg atactggcat ttggtcttgc taccgttatt gcaggcgttg atgctttctt 3420 tttgatgcgt tatccttcgg tctccattgc agctatcgtt gctcttcttg tagcatatcc 3480 attgggtcag ctctggtatt atattattcc acagtgggaa ataaaactcc caaggggtat 3540 acgtgtttca cttaatccag ggagattcaa ccgaaaggaa catgcctgcc tatatatatt 3600 cgtcaacatt tgtgtctccg caaaactagt taacacttta attatcgaac aaataaagtt 3660 ttttggagtt aacatcggaa ttggtagagc cattttattc aatttatgta gttatctttc 3720 gtcattcgga tggtcaggtc tcgctttgcc aattctagtg tatccgccaa cattgatttg 3780 gccttctgtt ttgagtagct gcgcactttt caagatattt cacgacaatg ataatactaa 3840 ggcctgcaac tggacaatct ctcggcttcg ttactttttc atagtttttg ttgcttcttt 3900 catatggtat tggtttcctg atctgatctt tcctgcttta agctccttgg gtgcttggat 3960 cagttggtgt aagccttcca gtgcagttct atctcaaata tttggggtaa agactggact 4020 gggtcttttc cctcttacgc tcgactgggc ccaaatttcc agtttaagta atcctttgat 4080 cactccctgg tgggctacat gttgtatttt tacatccttt gtgttttgga tttggattgt 4140 acttccaggg ctttactatc aaaattactg gcaagttgcg catttcccca ttatgactaa 4200 cagtatttac actgtttcgg ggaaaagtta tgatgctcaa aaagtggttg attcgaaatg 4260 ggagttggta actcaaaagt atcaagaata ttctccggtt atgcttccta ttgctttcat 4320 cataaacata gccttgtcat taggcgcatt ttcttcaatg atgatatctt ttttccttcg 4380 ttttcctacc gatgtcattc agccaatctg tcacgttttt aaatattcag acattcacac 4440 taaactttta aagaaatata agcgtgttca ttggggattt tatttggcat caataatagt 4500 ttccttagga ttaggcttcg cttttacaga aggatggcat gatattcaga ttagatctta 4560 tggatttgtg gtctccatgg ttattggagc agctttgtac ataccgcttt cattaatcga 4620 gtctcgttcc agcttcacta taagtatgca ggcttttttc gaaatagtgg cggctttctg 4680 gtttaatgga caacctatgg cattgctcta cttctactca tttggatttg ggacattaca 4740 gcacgctatg catatgactc aaagcgccaa aattggccat tatatgaaag tccccccacg 4800 gttagtcgct gctcttttgt ttacaagtgg aatttggtca tctctggtta attccgcagt 4860 aactggttgg atcatgtatc acgttagaga cgtgtgtact tcaaatgcgg aaaataacat 4920 gacttgccga tctccaaaaa ctcaattcaa tagtcatctt atctgggggt tagttgggaa 4980 tcacattttt tcatcagatg gtcgctattc atttgtaatg tggtttttcc ttgtaggtgc 5040 tgtcgtttca gttgttgttt atttgcttca gataagtttt cctaaaagct cttggaaaca 5100 tgtcaatcca gctctcctcc taggcggcgc tgctcagata ccgagtgtca caggaatcaa 5160 ctattcaacc tgggctgcag tcgccttttg tttcaattat ttaattcgtc gtggttatta 5220 ttcgtggtgg aagaaatata acttgataac tgctgctgca atggattgcg gagtcgccat 5280 tgctggacta ttcatatatt tttgcgttgt atatactggt ggttcaagta actttagctg 5340 gtggggaacg actgtaagtt cggcgggatg tgacaaaaaa ggttgtgctc atttatctgt 5400 ttcggatatt agcaaacctt ctggatggtg agtttgttgg caaactcatc ttttctaatt 5460 gtttgctttt tattagcgat caagttatat tacctttggt gttttgtact tgataaaacg 5520 attaaaccct tttcaattta caaagtttcc aatcataaac agcgcacttt acaagagccc 5580 tcactcattt ataaacgcga acgctgaaat tctactttgg ccccgtagcg ttttattcga 5640 attcaaagta gcagtaattt tgagaagttt aacctatcaa aaatatttta tttctataca 5700 agtagcacaa aacgactgtt ttcctttttt tttttttttg tcggtgagtg atggttccaa 5760 tatatgttac atctttatac tgtcagaatt aacctattgc gggattactt atatgttcat 5820 cgattacatt tccagtctat ttgttttatt ttatagactt tctgaacctt taggaatttt 5880 tttccattca ttgttagtga cacttactat ccgtttattc attacttgca ctctctattt 5940 agcttttatt ttcgatcaaa gttcttaatg aaacgcctta cgttatagta tatccatttc 6000 aaatgtaaat gacttgatgt ctgtatttct ttgggcgtag ttaattattt tcatacgtgg 6060 caccaatttt ttataagttc atatacatca taaattaaat cttttatgaa tgaatgtctt 6120 tgcttaatac atcctggact catttttatc attcgctaat gatatacttc attaagaaaa 6180 agggttttta ttgtgccagt actaactaat caatcatgaa aacattttta actagctctt 6240 aattatttcg tgtcatttat tgctcaaaaa gccaaataca ttggcaattc gatggtgttc 6300 ctgcctagat aacatagttg cgacgcaact tcaccacagc catcgttggc ctgaatttga 6360 aaagtaataa ccactacagt agaggcctga tattaatcaa atatggcttc caaacaaaga 6420 gaaaatgtgt tcccaacgag aatgtacgct cgaatgctct taataagtag ctaattttat 6480 taggaccctg acgactatga aaacacgtct taagggcgct caaaccggtc attctttgtt 6540 gaagagaaag tctgaagctt tgaaaaagcg atttcgtgaa atagtagtaa acattgagca 6600 agtaagtgcc tgaatacgcc tagttatctt ggacatcgaa ttattcattt tgaataaaaa 6660 taaccgtcat atgtaattca taaaaatttg cagcaattca aatttttgct aaaaaatgtt 6720 cccttggcac aataggtatt tgtctgtttc ctggtcattt acaaatctac tgtgtattat 6780 aggtatttta ggattctact ccttgttcag actaggcata ttcgttcgca tgaatccgtt 6840 aactaatgat atcttgatag gcaaaacaaa agatgggccg tgtgatgcaa attgctgcct 6900 tttcgatggc cgaagttgga tttgccatgg gcaataatat taatttcgaa atccaacaat 6960 cagtcaagca acctcgtctg cgtgtacgat caaagcaaga aaatattagt ggtgtattcc 7020 ttcctacttt cgagatgaat ttggatgaga gcatagatga ttttcaatta actggtcttg 7080 gaaaaggtgg ccagcaaatt caaaaagctc gtcaggttta tgaaaaggca gtggaaacac 7140 tagttcaact ggcatcttac cagtccgctt ttgtcttact tggtgatgtt ttgcaaatga 7200 caaatcgtcg tgtaaattca attgaacaca ttattattcc tagacttgag aatactatta 7260 agtacatcga atctgaatta gaagaactag aacgtgaaga ttttactagg ttgaagaaag 7320 tacagaagac caaggagaat gctgaaaaag cagattccgt tactaaagaa gagcatcaag 7380 gtggcagcaa tactttacaa cagacaaaag acgtcggcgg agcgattgca ccagctgctg 7440 aggttggaaa ggaagtcatt aatgaggtcg agaatagcaa ggatgacacc tattctttac 7500 cctctacttc tacggacgat gaagaagaaa acgattctga tgaagaagtc atcttttaag 7560 caatatgacg cagaagaagg gaattgttta ttacatattt cattaagcaa ttacccgagg 7620 cttccaaatt aatttaatga tggttgaggc tgaaggtttg aaaaatatct caagtttgct 7680 tttatacttg atgttactgg aaatttcgtt tctttcgttc tagttacagt acctcatcct 7740 cgtctgctca ttatgttcct taacagttca ttcataggat tgtatccttt tacgatatct 7800 attctcttca tgtttaagtt tttttcttac tttttgcctc tttctagaat ttagttgcaa 7860 ggttaatggg ctttttccga ttaagattat gaaaatttgg gttgtacttt ttaataattt 7920 tgctgctact ccagtttacc caaccttttt ttgctatacc aaataggcga cttaaaatta 7980 gtttttcaaa cgattttcca cttgtccatt cttttgaact actttttttt gcttttgtaa 8040 ctctgcaata atttaaatat atataatttt cactttgtac aactacggtt gttttttatt 8100 tattaactga aatagaactc aaatgttgaa tgctcaaaaa ttcattaacc aaactacaaa 8160 aagcttactc caaaagagtg taaaatattt ataaccttcg ttctcatgga agggggtcat 8220 tccattaaat tttttagatt ttgattatat catcagcata ttgtacaaaa gaatttaact 8280 cagcattatg agtatcctcc tataccatga ctctaacagt cttggcttaa cttagcttat 8340 tacgaagtaa atcacggtct cctttaacga cacggttcat ctcttcagcg gtcaaaaact 8400 cataatcgac tagagcagta gctaatgcat ctaactcttt cttgtgagat ttaagcaaag 8460 ataatgaacg ttcatatgac gcctcaagca aagacttgat ttctgattcc actagcgctc 8520 tcgtagcagg tgagagatta tccatttcag cttccaaact aaccgggcca atgcggtcag 8580 acattccaaa ctccgttacc atacggcgtg caacttgagt agccttgtct atatcattat 8640 gtgcaccaga cgttatttta tcttttccgt acaaaagctc ctctgcggcg cgaccgccca 8700 tggtgacgtc aagcatagca agatattctt cacgcgtcca gctatcttta tccatatctg 8760 gtaaggaaat cgtcattccc aaactactac ctctaggcat aatagtagcc ttgtagggtc 8820 tcatagcatt tttggtaaat aaagctacta atgcatgtcc accttcgtga taggcagtca 8880 ttagcttatt ttctggagta atgaatgcac tttttctttc agcacccata agtattcgat 8940 cttttgacca ttctaaatca cgcatactga ctgcggttga taagttttta ctggcataga 9000 cagcagcttg gttgattagg ttagctagat cagccccagc aaacccagag gttcctcttg 9060 caataatgct gagatcgaca tccttgccga gaggtacatg tcgtgtatgc tgcagtaaga 9120 ttgccagacg ccctctaaca tcgggtaaag gaacatgtat atggcgatcg aaacgccctg 9180 gacgagttag cgcaggatcc aaactttcgg ggaaattcgt agcaccaata aaaacgactg 9240 gatgagctaa atcttcattt tttgaaaacc cgtctaaatc aactagcaat tggttcaaag 9300 tctgtctcat atgagcggcg tctcgtgcat ttcttttttg tccaatagca tccaattcat 9360 cgataaatat aatggaagga gcttgctttc tagcggcagc gaacaattct cgaactcgtt 9420 tggcaccaac acctacatac atttcgtcaa actgactgcc actcataaag aaaaaaggaa 9480 catttgcctc tccagcaaca gccctagcaa gcattgtttt tccagttccg ggtggtcctg 9540 taagcaaaac acctctaggc aatttacctc ccaaccgtgt aaaatgagta ggatcgcgca 9600 aaaaatcaac gatttcctcc agttcctcct tggcctcgtc aacaccttga acatcagaga 9660 agcgaacatt aatagctcgc tcctccatag gttcttgctc agtagtgttg gtcattatat 9720 tgttaagacc tgaagtttca gcaaaaatac tcattcctaa aagaacaaaa taggaggcca 9780 cactaagacc agcaatgaat ttaaaaattc tgaaaaattt tgtaaatctc ggttcatcaa 9840 ctaccacata gacaggagtt ttactacttg tgcccaatgc tgatgaaaca atcgtgggtg 9900 cccataccgg aggtggagta ggagtcgaag gtggcatgga attttgcaaa gaatgattaa 9960 gtgaaggagt cgaggaaacg gtagaagatg tatcggatgt gaattttggt acgcctgccg 10020 aaaatgcttt tggatcactg aaactagagg tggcaggtga agaagatgat tgagataagg 10080 atatgttgtt cgataaactt ctgctccacg atttttttcg caaagcctct tgataatatc 10140 gatcacatgc ggagttcctg gcaactcctt gtgtttcata acggcttata attgcttcgg 10200 ggaagttatc agctagctcc ttatacaatt tagcctgcat atatgggtct gacatattag 10260 catttgccaa atcttcaaaa tgcgcaagct tttgttttct aaggggatga agccccgaag 10320 ctaatgcata gctccgagtt cgtagccatc catgaacaat gctattgtta aacaaccgtc 10380 ctccgaattt tgagcatccg gaatacaaga aacttgtctt tccctatcgt caagtaatga 10440 gttagtaatt atttatgacc agcttcctta agcttatcta catcgcgttt tgtaccatac 10500 atacgcgatg tctaaaatac ttacgaaaag aaatatagga tgcaaaaccc ttgacataaa 10560 ttttgcaata caaaaaggtg ctttcacgcc aaattggaaa gctaaatccc aaacaatggt 10620 ttcaacgttg ttggtaaacg gtaagtgttt agagcataat atttgaatga tgggtaacaa 10680 atacacatac agtatgaacc aaagatccac tatatagaga tgcggcactg tagacagcta 10740 ataagtaaca taagtgacag cgatatcctg aaaatcaaat atattatgtt aagagggaaa 10800 acctgtttga tataattatt gattattatt tcaagtcagt atttgaaata aattatctaa 10860 aagaatatgt tgtatataaa attataatat cctttttaaa actgagcgat ggatctgtcc 10920 attcagaaag ttgctgaact gagaaacaat gttagaatct ttaacttttt tttttcaatg 10980 taattttttt tgatttcttg tcctcttgtt tccaccttga cttatgagat cactgggttc 11040 ggttcatgca taatacgtta aaaataacat aaatgaagtt aatcattaat tctccaacta 11100 taaaagaggg ccaagttcaa gcaattgact ttaaaattgg tttgttgatc tctggatgat 11160 aacagtgtat ttttgcattc gaaatctaaa gtaaacatct cattgtaaac gcgacaggcc 11220 atgggaacaa aaaaaagatt tattgagcat ccaaggcaat ttgatatttg aaaattaatc 11280 gttgctgaga tttttcattt gcattgttta tagaacgaaa gaggaactga gagaacacat 11340 taataaaaga cattgattaa ttttgacagt atcactttga gatagtagaa ttttttaatt 11400 tctacataaa tatataatag gcaaagatca actgttaaca ttataaacgt tattccaatg 11460 aattaagaca tgggtcttga aagaattttt ctgcaaagat tagcaatgct caatctcaaa 11520 aaaaagttag acaacataaa aaaaatgatc gtattggata gaaaatctag ttatttaact 11580 atacatcaat acatatgggt ttcaacttcg catctaaatg aatcgtttta accttaaaac 11640 aatgtccttt gctcaactgg agatggtcgt tattcggtta ttcaaagctt aaatagcgaa 11700 gctcgtcaaa cttacaaaaa gaagtaccgc aagcgaacgc cttagatttt gtattttcat 11760 taatttcttg caagttaatt gcttagtatg agaacatgag atgctaggtt ctttgctatt 11820 ttcgtaaatc ggaatgtgct aagattcttt taaattgaca tgtcgaagaa tagacaattg 11880 attactttga tggaagtggt taacaatata atatgccaag gttgaagaat tacaacatag 11940 agtacattgt ttaagcgttc gttaaaaact actaaatagt tattgatttg atttaccaca 12000 gttctaaata aatttttttg ttctctgtaa tgtaaaaaga taattctatt tgcttgcttc 12060 tcagcttgta tttgattgat gcttgagtaa aaaaaatatc ggtcgcttca accaggttcg 12120 ataaatttca taaggaccaa gaattatgaa gccatttacg tcttttacga tgctgttaat 12180 ttttaaatta ctttactacg ctagaaacca ccatacattg cttataatta gatttattgc 12240 taagagcttg tattgtaact tgtcaatcaa gatcaaattg attctttacc gtaatataaa 12300 aaagaaaaag aaaatttctt taaagaatga gatttagact gcatgtttca ctatttctcg 12360 atgcctgttc acttcttcgg caaaaaggtt ccaaagattt tgcttttttt catcagagta 12420 gcctgcagca cggccactcg agctaatacc gacaaacacg tttgcatccc caaatttctc 12480 tggctgccat ccaaaaacaa aggtcttggg caattttttt cctgtaagca ttttatacat 12540 ttcctcccat atgcctttcc cggaaatgaa caagcctact tgaggacggt accgcttaac 12600 cttttcataa agaatacgag caccatcttg catttcctct ttgcgtagat ccgctccact 12660 agacgaaggt ctcgcacaaa gattagttat acctaaacca tgagcaggta aatctttatc 12720 gttaaggtac gtgaattcgg catttccctc caaaagtttg cttttattaa gcattttcca 12780 aaatctattg ctaggtgaag caaatgcgtg tcctttaaga gaagaagtaa tacctggatt 12840 gagtccgaca atgatggcat acggattctc gcaaatgtaa tctggaaccc cctgcaataa 12900 cgcagggtcc acctcattct tctttttaag cgtgcttttc ttaacagatg ctttgagggt 12960 acttttctta gttacattaa ccctacgatt tcttaagcca ttttcaagcg taattgtctc 13020 aaccgctgac tttaacaacc cgttgtctgt atcagaattc ttcacgacat ctgttttacg 13080 atactcatta ttgcttcctg catgagcaaa gcggaatcgt tctagagact ccgagaaact 13140 ttgggttttc gccttcttca aaatcccacc actggtttct tcacgactct cttcgagctc 13200 caaattttcg tcatcaaaac tcctttttct tttgtgactt tttaccgata aattaaattc 13260 tgagctgtta tcattcttcg ttcctgtgtc tctcgtctca atgtcgttca tacaaatttc 13320 caaaggtata acctcttttt tttcctaaaa tattcaattg tccaatatat agttgctcaa 13380 tagctgcttt caatagtttc ctaacttata cagcgttcaa aagacagatg agtaaaagac 13440 gattaataag gggatactca catgttggca aattttaaac acttgctaac gctgtttatt 13500 ttaaacatca ctttaacgaa ttctaaagct gcagcaaaat ccattaattt atcgacagcg 13560 aatttcctta atacattagg attcagtatt ttgtctcgtt gataaattat ccagcgcaat 13620 gggatttaca gctacaaaat gcgaaagaga gccggtactt gtttaggaat tactcaaaga 13680 gtgtgaaggt taaaattatt ttttcagacc atcatgatgt tatgcttagg tttacttcaa 13740 agtcaacaaa gatgattggc gtgtaactgt gtttatcgcc agatttcaac ttcaattaag 13800 cccaattatt tattaagttg attgtcaaaa taaaagaaag tgaataaaat aaatttgctt 13860 ttcattgctt ttgccgtaac attatgaata tttatcattt agtgagcaat attaatcagg 13920 aaaatagtaa actgtagtga tcctactttt taagcctacc attgtaagta cattattttt 13980 cagtaaactc caaaaccaga aataatgaaa caatgaacgt aaaaatagtg catatggttt 14040 gaacgatact ccataatcaa ttgtgtttaa tcgttcgact gcttttgcag caagtggtat 14100 tcttcatagg aatggtgatt gcctgttcaa atgatcacac tccatactac aataaaaccc 14160 aacctcccag ccatctcaac atgtaattag tcattatcaa aggcatgctg gcttctcttt 14220 tgatttcatt cctttaaaat atatagtaaa gacaaattag gtcttaaaac tatatatacc 14280 tatttcgata cttttgctgc tacacttcta atcggtgaat aacatatgct tagataccac 14340 gcattgcaat tccaaacgca tctttttaca actccttatt gtgcataatg ttcattatga 14400 agcttaataa tcacgtgtag tgagatattt caccatgata gtaaaataca tcaaattgtg 14460 tgctgccggc acagttttgc gtaacaagat aatgaaaatg gccatttgaa tctcaatata 14520 tgacgcattt caacggtata taaacgttca aagacactgc atggattatt gttagcttat 14580 ttttatctag caaaaattaa aaaatttgag gaaagcatgg ccagcgcaac tacacatttt 14640 cagccgaaaa acgtaccttt tcgctttcta gggcgatcag gtttaaaagt ttcggcattt 14700 tctttaggcg gttggttgac ttacggcaat gagggttacg atgttgagca tactaaaaat 14760 tgtttgaagc aagcatggga tttaggcatc aacacttttg ataccgctga aatatatagt 14820 aatggaaatt ccgagaccgt aatgggaaag gcgattaagg agctaggttg ggatcgatct 14880 gaatacgtta ttaccaccaa ggtcttcttt ggtgctggta ccaagctgcc aaatactact 14940 gggctgtcga gaaagcatat cattgagggt ctgaatgctt cgctaaaaag acttggatta 15000 ccatacgttg atgtgataat ggctcatcgc cccgacccct cagttcctat ggaggaagtc 15060 gttcgagctt tcactcaact gatacaagac gggaaagcat tctattgggg gacttcagag 15120 tggagcgctt ttgaaattga gcatgctcat catattgcta cgaaatacaa cttaatagcg 15180 ccagtcgctg accagcctca atataactat cttactcgag atcattttga aaaagaccta 15240 cttcctttac aacaaatata tggctatggt gctactgtat ggagtccctt aaagtccgga 15300 attttgactg gaaaatacaa tgatggaatt ccggaaggca gtcgtttaag cactactttt 15360 accagtctcg ctggtcaatt acagacccca gaaggtaaga cgcaacttga tcaggttcgg 15420 cagattagca aaattgctga acagattggt gctacaccat ctcagctggc tcttgcctgg 15480 acactgaaaa atccctatgt ttcaactacc attttgggcg ccagtaaacc cgagcaaatc 15540 gttgaaaatg tcaaagctgt ggaatttatt gataaactga cgccagagat attaaagaaa 15600 attgatgaaa ttctcaattt tactccattg gaaattcagt atcgtcgttg attgtacatt 15660 cccatgatga ttatctgtca gctaggtgtc ttttatttta agtaaaaaaa ctttaccaat 15720 tcattatttg gttttgctta gaatataatg ttatagaaga aatgaaccgt catctttata 15780 tgtcaaacgt tcaaaatctg ttcaccgcat tttgtcgatc tctgtaatta gtaaaccaac 15840 tatagacatt tttaaactta ggttttatag tcaatatttt tttaaggttt aaaacagaca 15900 cacgtacact attagtttca attttacatt ggcgttttaa gaatttgtca gcaaatgcaa 15960 gttaaatagt atggcatgaa ctattgcttt tttgagataa tggaccaacc tagctttttt 16020 tattgatcac tcgttctcca cgcgattata gttaaagtta atttagttga agataatatt 16080 tgcgattgtt cacaatcatg actaactcta gaacttattt taatctttcc tattcataca 16140 acagtcatca atttatcgat ggtaaacaac cttgacaaac aaaggtttta tatgatttac 16200 ataacattat ttccttcact gctcgccaaa acccttctga cgatatagat ttttgggcga 16260 tgatttagtt aagtaagttg atttgtttaa aagcacaaaa caataaattt tttaaaaata 16320 attcatttag caaagtcgtg gtcaaataat ttatatatgg ttcaataact atccatgtta 16380 tagttaattg actgtattac aactgaaagg tatatttcag gtactataat cgcgtatgga 16440 ccaaaaatgg aatgaccata aactggctag gttatgcaac agggaagaac gaacgatatc 16500 agagaaaatg attctgtatt gatataatcg atttcgtaac caagtaatct tctcaacctt 16560 gttctgagaa taaagtaatt atgcaagaat atactgcaaa ttaactgaag ccgcaaccat 16620 caaaaaacac atatactatt atcatcagcg tatagcttat taagcttaaa acataacatt 16680 tgatatcaat agcaatggaa tagctcaatg ttgttctttg gcctttgcca attcttcgaa 16740 agtagccttg acagcaggtc gtgcaagaag tctttgattc caagcgtaag ctttaggaaa 16800 ctctttttca aaatcaagct gaggaacctc ttccttgaat gaaaatttcc cttccccgaa 16860 aagaccgcca aggttgtagt tccaaggaat aaacgataaa tcagcaattg tatacttatt 16920 cgctacaaga taatcacgat ctttaagaat atcttcaagt actccaagaa cacgctttat 16980 ctcatttcta taacgggtga ctgcagatac cactggctca tgatggaaaa agttgaacca 17040 tccagcttga ccccaaataa cgccttgtcc agaagcttgg aagaacaagt attggataag 17100 tttatagtat tcagggtcat caaaggataa tgaaatcttt cgatccgtat catacttgtc 17160 agccaaataa atcaaaatgg cgtctgattc ccaaatagta taatcattgt ttttgtggtc 17220 aactaaagta ggtactcttc cattggggtt taaagccaag tgttccttgc atttttgttc 17280 tcctttttgg aaatcataaa atatttgttc gtaagaaaga ttcaattctt tcaaagcaag 17340 gaccaccttc caaggattgg gtcctccagc atgcgagtat aaagtaaaat gagccataaa 17400 attggaattc tggctaaaaa tttgtaattg gtagtatcta aaactagaac gaggatgcct 17460 gacttttgta tgtatcgtat tactgagtgc ttatgtaaga aatttgtaat agcctaaggc 17520 catttgtaat aattgttagt cagcacccat tttaattagt aattaataac aataaatttc 17580 tttatattcc ttatttttcg ttaccgttga agcgtgggtt tttacagtga atcactagta 17640 tgctcaaaag tcaaggaatg aatgattaat acacaaatgc aaacagcatg ttgaatgaat 17700 ggttttatga gagatcaatt tagctgaaca aaaaaaaatc gtaattacaa gcacggggaa 17760 actattttat actaccggta caaacagctg acatcttttc atttttgctg ctatttcata 17820 atatcgctga tacttgattc ttctatctga tttttcgtag atactgtatg tagaaagaca 17880 ttctgaacga attcaaaact caaggtgaac cgactgtttt gcatcttcaa ttaccaaatt 17940 tgagttgtta aacaacgaat ggtcgtaaag cttttccaat tataaatagt accaatcttc 18000 tttctctgtc tcatttatat aatatacatg tatcttattt tacttttctt gcagactaca 18060 tagatttaca catccttctt tacctataaa agaatgtact cgtaatttaa tcgacgaata 18120 atgaaaacat aatggttaat tttggtctaa gtttaataaa ttgtagatgt ttaatttatt 18180 aattggacac ttcagtattt tagtaaaacg tcgtgtctta cacgcagagt actctcctgt 18240 ttttctttta ctaactattt agttaaaaac ttaagtcttt atataaactt ataagattat 18300 tcgacccgct ttctctaacc tcaatgtaca tcaattcgtc aacaaactat ttgagcaaat 18360 tgaatgtgta cgatttatga aagaagcatt acgtcttgtt agctttaagc tgcattagcg 18420 atagcttaaa acatataagg ttattttgtc tggctaatat ttcttcttgc ttcataaaat 18480 tggaattaca caactcttaa aagtcattgt agtctctcac acttaataat ttacttggga 18540 ttttttgccg tttgtgaagt agtgcaaaac ctttctaaaa atttttttac agctgcaaca 18600 gccaatactg gtgctgacaa tcatagcaca aaacgctttg cgcgtagaaa taaatagaga 18660 agtttttaac ctttagaaac ttccttgatt ctattgaagt tgactttctc ttcattcttg 18720 tgctacttac ttatgcggtg aaagcgttag attatgctgt tttcttttat aacttggtaa 18780 accattgata ttaagtatga gattattcag gaacaagcgc atattgtaaa caaaaaaaga 18840 ctataaaaaa ggtagcatac caatgaagct ttgctcattt tatcaagaaa aattagtatg 18900 tgtactgtaa aggaactctc ctagtgagtt ttgttacaag ctcataaggg ctagtatcac 18960 tacaatattt agcaatgtct gccactgtca attctggagt tccccaaaat attacttcat 19020 cccctggctt gacatcagga atgtctgaaa gatcaacagt aagcatgtcc atggaaaccc 19080 taccaacaat tggagccttc acgccattca ctaaaactgg acatccatct ttaacttgac 19140 ggggaaatcc gtctccgtaa cccattgcta caacacctag tttcatatct ctagtagcaa 19200 catatctccc tccataacca atgggctggc ccttgtcaac atgtttcaca cttattatgg 19260 tagataccag tttcatggca ggctttatat taacagactc tggagttttt gagtctttat 19320 ttttagaaag aaatggagaa ataccatata acatgatacc agcacgcaac cagtctgtgc 19380 acacagtgtt tagccagccc aaaataatcg cagatccgcc agcactaagt ggacctggta 19440 aatgcgcaac agacttttca aatatatccc attgcttcaa agtgtgttcc ggattttcta 19500 gcatatctgc aaatgcaaaa tgagtgattt ttccgatatt actaacgttt ttgttattgc 19560 ttagtaaatt atagaacttc ataaactgac taggtgtaaa acctagacgg ttcattccag 19620 agtcaagttt caaccaaatc tctactggtc tgttgaaagg gtatttaata aaactattca 19680 cctggtcttc agaatgaatg ataatagaaa aattgtaatc atcaataagt tttaattcat 19740 cctcctcagt aaagaatcct tccaggagaa caattttgtt atagattcca ccgtgcctta 19800 attctaaagc ctcttcaatt gaagaaacac caaagccatc aattgaagag caatgtttga 19860 gaaggaaacg tgcaacttgt acagctccgt gtccataagc gtttgctttt acaattgcta 19920 aaacatgacc gcttggattt ttttgaagca tcatttgctt ggcaacatta taattgtgtg 19980 caatggcatg caaatcaatg acggactttg cacctctcat ggttaattta aatgaatcaa 20040 gatagaaatt tgtatagcaa gggacgttat cgagttattt cgtgaaccgt tgacaattga 20100 atctatgctt taaatatccc cattcaagaa gcgctatcgg aattgaagcc tcccagttga 20160 tttatttaag cgaatttact acagcatttc catatttttg ctatcctcac cgtgcatttc 20220 cagctgcaat cttcatcacg atacttcatc cattgtcgct taaatttatt tctggtttaa 20280 ccgactatcg agaagaacag ataatgtttc atttcgcaaa aaagttaact cagttaaggt 20340 ggatgtccaa gtttcgcatt ttaatttccg gttcgcggct aaactgccac ggaattgttg 20400 gcacttcaag gtggtgctaa aaaaattaca tcaaaacagg atgatgttct ataacattcg 20460 ttttgaaatg aaactgtttt tggtaataat aagaactacg tggtagttca gatcgtcatc 20520 aagttcagtg cataggtgtt ttgttagtcg cttcaattgt taagaaagtg ttcaagctca 20580 gcgattacta tcattatata aaaacacact caaaaagtat gtaggcttca atccaaatct 20640 gctgaaccaa aaaacaaaag aagaaaatga tatttaccca ttacgactaa acttaatttc 20700 gataaatcaa aaaaatcttc gagatttaaa ttagcgttag tacgatgata ggtgatgtat 20760 taaaaataaa ttaaggaaaa taaaacaaga agttttagaa atgcattatc ttggaagagc 20820 ttaaattgta acatttggct ccaaacacta cctcagtgta tcccaatata taaaattcag 20880 agacttcttt taaatacgga tcaaaagaaa atgatttttt aattctcttg attggtttta 20940 tttgaaatta aaagaattcc tggaacaggt catatctgaa gcaactggta aattcaacaa 21000 gcggtaagta atctgcaaac aacgcagaaa caaacaatga tctgatagat taagcttcct 21060 agttggcaaa gtagaaatac aataaactgc tcaggaaatt aattgcaagg catatggtag 21120 tcacttgtgg aaaaaagttg taaaatttta ggtcatgctt ttctaattaa gtacccagac 21180 aaacttgtca gcgcgccatt ctaggtgtta caaacgcttg cgaacaattt gagaccattt 21240 attcaaggta gacgacatca tttttagcag cttctcataa atgctccaag tccactcttt 21300 cgcagccagc agaaattcat cctcacactt agatcaatcg tgttgattta taaatattaa 21360 aaatctcaat aagtcattga tgataaaata aagagtttat gtttgaatat cgaaattcga 21420 agagtataat aatatttttt tttttttttt taattataaa gaaacagaga cgttttgtaa 21480 aacgatgagg gaggaaaaat atattttttt cttttcttgt tttaaaaata attcaactat 21540 tcagatatgg aatgagaatt aaacatttac ttgcttagaa aagaaataac taagtaaacg 21600 tgatctttta aggaagaata aatatcgaaa gaataatacc cacaaaatgc atttatttgt 21660 ttaccttggt aatataattt gcgtgctcag ctcacttcaa gtttctatac gtattcgaaa 21720 tcaaacacaa cctctattta gtgataacac tgcaaattaa tatgatgttt caaccgatag 21780 aaagtattac cacttaatac ccttgtatca gtacataagc attgtcactt atactgcact 21840 cgaaggtatc gtaaaaaata ttaaagatag agcgtaattt atttttatgt atgtcgttga 21900 tagcattaga atagtcttta cttccagtat cttgggcatt tcatggcaga tttattataa 21960 taatgtaagt aatttagaac gaaacgttct catcgttttc tacaacgttc gcttctaccg 22020 gaatcatgaa ggctaatatc gcgtgcgtgc aaatggcacc caaagtttgt gatgtaaaac 22080 acaatttaca aaagatgagt tcttatgttc atgaagtgat ggagtcaaat cctagcacaa 22140 acctaatctt attccctgaa ttgataactt caggatatga atgcggcaac acttttaccc 22200 aaatcgctga aattgccggt gaaggcccaa gttttaaaac aatgagcaat ctggccgcaa 22260 agtaccatgt taacattatt tacggattcc cagaaaaaga agagaagcaa tcaaatataa 22320 tttacaattc gtgcatttac atcaccgaaa atggaaattt aggcggtgtg tacagaaaag 22380 ttcacctttt tgacaccgag cgtaaacatt tcaaaaaggg ttccgatttc ccaatattcg 22440 agactagctt tggaaaatta ggtgtcatga tttgttggga tactgcgttt cctgaggttg 22500 cgcgaattca tgcgctgaac ggtgccgatt tactggtagt cgcaacaaac tgggaaaacc 22560 cttattccga cgattgggat ttggttacaa aagcacgggc ttttgaaaac tgcattccac 22620 tggtggctgc caacagagtc ggtacagacg aaaaactttc gttttttggg catagtaaaa 22680 taataggacc aacggggaaa gttataaaag ctttggacga agagaaagaa ggtgttattt 22740 cgtataccgt tgatctggat gatgctaaac ctctgaggaa aaactactac acattctttg 22800 aagatcgaat gccagatttg tacaagcgtt tgctaagtcc ataggccacg gtctcttgat 22860 tacacttttg tacttctttt actatgaaaa attgaacagc tatctacttt tacatttaaa 22920 atatttataa tgtttagaag tgaaataacg aaaaataatg ttcaatatat tataaatatt 22980 attaactttg tccttctttt tttgcaaggc aatatctttc tgttgttttg aagtgtgaat 23040 ttcaattaaa tccagaaaag gtcgattgtc gtactgtata aaagctcata cacaatttaa 23100 tgaccttaac tatcctttca agcattcgat gagtttagtt tgattgtctt cattacttta 23160 cagtttatag ctttttttgg agtaaatgaa atcggactca tttactccat catcgtcact 23220 attctaatta cacttaagaa tatgtcaaat tcttcatatt tgtagggagt ttttaccatc 23280 tattctatta gactttaagc accagaaaca gtcagtccta agtttgtaaa actgaatgca 23340 attgaccgca actaacttca gcgttttgtc acttccatca actttttcac tataataaac 23400 caacgcagta atttttattt gaaactaaac atatgtaacg gtgagtgata aattcaggta 23460 tcttattgca gtcggagttt gaaggctcaa atcatgataa gaggtttgaa ggcagaagaa 23520 cagcaactaa ataaatagtt caaaaaagct taaggattat gggatgttaa ttttcaatct 23580 tcagaattaa caatgccaat tcatccttgc tatagaaaaa cccttacaaa gcagcacagt 23640 ttattacgac attaattggt ggaaccgtat cgagtttagc gagactacaa gcaaatctat 23700 cgttatcggc tgataagcct ttttggaaaa cagattgtta gatataatga ctttgtacgc 23760 gctagtaggt aggcggttta atttgtaaac aaccataata tgtaaaattc aataaattgg 23820 ctaaattgaa tggtaccgtt ttgaagaagg gaataaatag tgaagagttc taccaaaaat 23880 gacatcgaca tctcattttg tagctagtac tgtgaaaaaa ccaagatcgc gatacggatg 23940 tttaatctgc agaagcatgc gcaaaaagtg cgatgaggtg catcctcaat gtggacgttg 24000 tcttaaagct ggtaagcaat gtatttggaa gcagcctggc actgaaagaa agaacaagac 24060 gaaatggaga aaagcaatgc agaacaactc gatcccaatt caggatttag ctgatgattt 24120 cgagcttgat tttcctgata ctttagacct aacgaatcct gatgctctcc cggtacttgg 24180 tgaatcaatt gttaatccta tatccttacc ggtggacgta gcgtctccat ttttaccctc 24240 tgaatgttac ccatcaaaag tcgaattgcc ctactttcct ctcctttcta aaccgaatac 24300 cttattaagt ttattaaacg atgaagaaat ctcctgttgc gagtattatt gctattcagt 24360 agcacccatc accacgattc ttccgggtca accaaatttt ttacctcaat tacttcttcc 24420 tatggctttg cacgaagaat ctgttttgta tagtttagtg gcttcgggat acaggttgaa 24480 atacggaaac gataactctt tggcacttca aaaatccaaa gtttttgtga atcgtgcatt 24540 gttaactcta ccggaacgtc gatctttaaa tctctcaaaa tcggaatttg tagtatcttt 24600 agcttgttat attcttttgg tttatacgga aattgcattt gccgatacta cggaatgggc 24660 aacatatttt ttaaatgcgt ataatatgat taacaaaatg ggcggcttta aaattcttaa 24720 agagtgctca tcggaaggaa aacttttagc agaatgcttc gcatactttg atatattagc 24780 atcacaatct aatttgaatg ggacatatta ttcaatatct gattatactg atgtctacgg 24840 ggtcgacgag ctacaattat ttgaatcatt ggaaaactgt atcaagccgt tagtactaat 24900 tattggagat atcattaatt tattggttga atcccgccgt gctggattcg atgatttgca 24960 acacacatta aacatctatg aaaaatcaca aacaattgaa ggaaaaattt ggtcatgcgt 25020 accacagtac gaggatatga aatctaacaa acttgattct gaaaaatcgg aacctttgca 25080 actttttaag ctttataaaa caacaacaga gatgtacctc agacaagtga tcagtcggat 25140 gcccccagtt tctttagaaa tgcaagtgct tttgcataaa caaactcaac ttattgattt 25200 gttactcgag tcatctctaa gaaactcact ttcctttccc atgctgattg cgggactgaa 25260 tgctgcaact gatttacaac ggaccaattt taaaaataga gtaaattgtc tttgccaaaa 25320 ttatacaatt ggtagtctca aaaaggtttg gattgtggtt caggagattt ggaagatgaa 25380 tcaaaatggg aatatttgca ttgactggta tgaggtggtt caaaaattcg gatggaggtt 25440 aaatactggt gtataaaata acaggattat acttctttcc aaactctgtt ccagaaactt 25500 gtttttttgc cgtcttcggt ttctttatct gaagactgtt catttgaata ggttggttca 25560 ataactcgtc tgccgtttat gaagtccatg tcttcataag atacccactt tgtcttttta 25620 ataaatttat aagatagcca aatgacgaaa aacaggggta gaagtatata ggcatcgaca 25680 aaatcgccag cagcaaatgg tttaaaaacc gtccatcctt gtactagtgt gagaatgatt 25740 cctataacga atcctataag ctggggaaag ggataaagag gtgatttaaa cggtaaatca 25800 gacaaggcat agccttgctt tacccagcct cgtctgaaac gaaagtgaac gaatatgatt 25860 gctgtccaca caatgaatgc agacacacca gctaaattga taatatagcc atatgccttg 25920 acagcacctg tgctgtaatt cataatggaa agaaacccga aaaggtggac tgagtggacc 25980 gcaacccatg gtacacctct tttatcaacc cttttaaaaa tttttggagc catgccatcc 26040 ttggctaaat tatacaaaga tcgacttcct atatatatac cactgttgat ggaagaaagg 26100 caagtaatta aaatgactgc attgacaaaa tcacctgcgt gattccaacc ggcattcatt 26160 atagcaattg tcattggaga cttgagagtt ttggagcctg acgaaagatt tgggtcattc 26220 catgctacgg tgataccgta agagattgag ataccaaaat agacatacaa gattctccag 26280 aacgtttgtc tcacagcaag cgggatagct ttttttggat ttttgctttc agctgcagtc 26340 atagatacag attctacacc actaaaaaag acaccggcat atacaaatgc tgaaactata 26400 cccccaaatc cgtgtgccaa tggcatttct ttaaacaagt tgggcggctt atgatgagga 26460 attcctccag ctgcgtaaat tattgcaaat atgtagaatc cagtaataaa tagaagttta 26520 atgaaagcca aaatgtattc agattctcca aacactgaca cacctagcat ttggtaacac 26580 gtaaaaaaac cccaaaaaat tagaaaaaag ccataagatg gcacatgggg gccccaatat 26640 tgaagaatag atgttaaaga tgtatattct gctgcgatgt tggtaagcca tacgataaca 26700 tagttccatc cgatagcggc tccaaatgct gggtcaaccc atcgagcagc atgagtattg 26760 aagttgaaat caaatagcga attaaactcg ccgatactca gcataacccc aaaaacaaca 26820 atactaacga tggcaaagcc gacaattaga cccaccggac caccaatatg cagggcactg 26880 cccataccaa tgaagacacc tggaccgatg ataccagcaa gggccatcat cgatacatga 26940 cgagtcttca atccacgttt gattccattt gaattatttt ccgctgcgtc aactgttaca 27000 acttcggaaa ctccaatgtc gaggttttct gaggaggata gcttcttggc aggaactttc 27060 tcagaaggcg ctgcctccat tttcttaatt aacttaattc actttattct taatattaga 27120 aattacaatt ggtattgtga tctatatatg tacaacagaa ttgataaatg taatcaattc 27180 taataatgtt agctgcagaa tcaacatgaa ttctaccgct aattgctcaa aaaaagttgt 27240 tttaagcgtc aaatcgttta atcgtatctt tgacgctgtg ctaatcaact gcaattcatt 27300 ggaatttaaa gtgttattca aggtaagcag attatcagtg agatttttaa aatcgccaaa 27360 tttcgctaaa ttacttagcc tacaatgatg ataaagataa gcttctatat aagtattaaa 27420 aggtgacaga tttcaacgtt ttggcgatgc gtttatttga aggtgataaa atcgtcttta 27480 taagatgaga tttagcgact tgtttaggcg gcccatatat acatgtcggc aggaagacac 27540 ggttttgata tacccatatc tatatatatt cagataaatt ccatggtgat cgtcgcagta 27600 agaagctgat aatagttgaa aatgacggtt gatcttaggg aagagaaaga gctcgcacag 27660 caaagattta aagaaatttg caagcatgcg aaaattgttg atacacacaa tgacttccct 27720 tacctgctga gagttcaatt acgaaataag ctgcagctgg cggagtttga ttttgagaac 27780 ggtttaacta gtcacacgga tcttgtaaaa atgagacaag gtcaagtcgg agttcaattt 27840 tttagctgct tcattgaatg caaaaatccg aattacctgt accaagactt tgatacacct 27900 actactgtgg tgcgcgatac actagaacag attgacgtta ctcgcagatt ggtttgcaaa 27960 tacaataatg atttgaagtt tgtcgattgt gcagacgatg ccatagcagc gtttcgaaat 28020 aatgggaaaa ttgcaattgc tttgggagtt gaaggtttgc accaggtgga tacttctctg 28080 gctgtattaa gacaatatta ctcacttggt gtgagatata taactttgac tcataattgt 28140 gataacccat ttgctacggc agctagttcc attactgggg gccttccaga cagaggtctt 28200 tcagcgtatg gaattgagtg tatttttgaa atgaaccgac tcggtatgat ggtggattta 28260 tcgcatgtaa gccaccgcac tatgcatgac gccctcgatg taaccaaagc tcccgtaata 28320 ttctcacact cctccgcata cacacttaca gagcacgaaa gaaacgtccg agacgatgta 28380 ttggaaaggc tgaaaacgaa tggtggtgtc gtacaagtca acttttatca agatttcatt 28440 cgtaagcctg gaagcgaccg tgcaacaatc gatgatgctg cagatcatat cttacatatc 28500 ataaaggtag ccggttggga gcatgtcggt ttaggatccg atttcgatgg aattccccaa 28560 ggccccaagg gattggaaga cgtctctaaa tatcccgatt tgatctgtaa aataattgaa 28620 aggacgaatg ccacaaacga acaaattgaa ggattaatgg gtttaaatgt gctccgggtt 28680 tggaaaaaga ccgagttagt ggcattgcaa ctatctaaaa aattggagcc cattgaatca 28740 agttggtctg gaagaaagtg ggagttttac agctatgcta aagagtttcc agagctattt 28800 ccagacgcct ataaactgaa tgaaaagagt actgtttgga attatgatca gcctttgaac 28860 attgagaaat aatatcataa ggatcgttga ctttttaaga aggtgaagta accagctttc 28920 atttcgaggt tacaaaaaat aagtcatcag agagttttta gcagcatgtc cttctttcat 28980 acccaataac atgtttcatt ctactgattt ttaacctatg aattatccca aggaagatca 29040 caaggaccga ttgcaatttc ggttaagttc gtatccacat tgtgtagttt cgacaagtaa 29100 atatgaactt acaaaagttt ttctattaat cagtatagtt atagtagaga tacgttgaat 29160 aaaattatgt gttttataaa tcaatggaat aagcaagcaa tcagacccac ataaagaagc 29220 actttgctac atgaaaatcg cgctaaggaa tcagcaataa gacaattaga gaaatatgaa 29280 ataaagaaaa agaagcatgc gagaatttga tatgttgatg caatttatca atctactact 29340 ttgtaagcaa tgaagcaatg atttgttcga aagtcacaga gattcaaagt actgaaccat 29400 acatgatttt gtcaataagc taacagggca taaggcccac aatctatctt taaacaataa 29460 aattaaaaaa ataaaatagc aataataaga gaaggagcct acagcacccc ggattcccat 29520 gttgtctcca accatagtac taacgaggcc ctcagacgct taactgcagt gatcggacgg 29580 gaactggtgt tttcgcctag gtatggccgt agacaatgtt tttcaacaat agtaaattat 29640 atggtaattt tatgaaaaat tttatgatta actgttaatg aaaagaaaaa gtaaaataat 29700 gaagacgaca ttttgtcagt gtagactttt gagcatgaaa tttgtgaatg atcaaattcg 29760 attaattgat aatatttttt actacgtttt attttaccaa aagtatttgc aacatcatat 29820 cgattatgaa aaaaattttt ttttaaacaa agtaaattaa tatatttgtt ctattttcat 29880 ctgttaaaat tttatttatt ttttacaatc tattcgcatt tttaatttaa attaatttta 29940 ttattttttt tatatcattt tattttattt tactttactt ttttacggtt ttttttcctt 30000 gcatgtctta aaaaaacgtt tataacggta aatttgcata catgctcaaa agagaaaaag 30060 tcgcatatgt caatagtctt atctttataa agagtccaaa ttgcataaag ccggaccata 30120 ttataaaaaa caaagatagc taattgaatc atttgaacga acgtatcaaa catgttcaaa 30180 aggacacctt aatcacatga cttgtgcaat aaaatattaa aacggatttt agatgcggga 30240 tgactaattt gatgtggaga aaaaaataaa cgatagatgg taattaccaa atagtttctt 30300 ttgagttgca gaaacattgg caggtaagct agctatacca tgcaacaagg cctgacttgg 30360 cttccccttg tataacatgt tcatttgtag ttgcatattt gcagatcatt tttatacata 30420 ttctactttt tcacagacat ggctaaggaa gtatgtaagg aggaaatgta tgctaattta 30480 attctcaaca aatccatctt gttgcattgt cggcagtaga atttttgttt ttagttatga 30540 attacttttt gagtaagtac atataagatg atagtttaag aaggaaagtc gatctacaca 30600 cgtttaaaaa ttgttgaagc gattcgtgca tcggtcaatt gtatacttta aagcttttct 30660 ttccttaggt cacatctaga acttattgaa cacgatttca agttgtgaag aggaaaacgg 30720 atgcgatcca cttttaccgg agctggatga tttttccaat cacattgttt acatgtcaaa 30780 aagggagcac aagaagtcgt aaagcaagga tcgcatagaa aatgtaaagg aaattaaaaa 30840 aaaagatgaa tgaatgaatg aataataaat aaatggaaca aaaaaatgaa tgaataaatt 30900 gaataaatag attaaataac gagaacagaa aatagaatct taaaaaaaaa aaaaaaaagg 30960 acaaacaagg aaaccttaag ggttgcgtat gtttgtatgt gcttttcaga ttcacccttt 31020 attcgatttc tcagtattgt tttctttgcc tggctggctt accttttccc gtagatgcca 31080 gccatcttgg taaatgtaca tcccccacat agacccatgt cccccagtcg actgcaaaca 31140 tgaaccactt tgctactagc taaaaggaac tgactacaac tttgaaaaag ttcctatgtg 31200 ggggtgaggg gggaaagaaa aatgcggagg aagtgtttcg ggaataccgt gtttctgccg 31260 aagtctttgc cggtcgtgga ccgggtgtcc gaggaattcc ctcatgacaa cgaagccgag 31320 ggtgtcgcaa atgggatagc gagagaaaaa gagagagagc agctgaaagg aaatagcgat 31380 gagagacgag gaagagagag aagaactgag taatgcgata gaggaggaaa agagaggtgt 31440 gttatagcac cacacaattt tgaaatgtaa aataaaatca aagacatgat gaatcaatca 31500 tctttgtgat aaatcaattc aaacaatcaa tggtgctttt gtgcatagtc aatcgtccat 31560 tgactattca actcattgac ctattcaacc catgacaaac atagtgtcga ccttagcctt 31620 ttctcatccc attttatttt tcatcctaca tctttacgtc tacaatttac gcatcccttc 31680 atcaccaacc caatccttcc tacacctatc tccatcttac aaatcttact cattcatttg 31740 atagctagag ccatcatcct gtatatagac tcaaaaagaa tggaatgggc cttgtctttt 31800 ccatctttct ccatgatacg aatttacgga ctagtgtgct tgtcactttc cactcgctaa 31860 tctctagcac gtggaatgca accgcacagg gaaacgagga tgtaaagcac caagcaaaag 31920 caatgcagtg gaatacgaaa acggtgtgtg taacgacata aaaaaaatct cattcttatc 31980 agtaatgatt agatagtgtc ttgttctttg tctttgtttt tgcttcttga cttgcccgat 32040 atacttgtat taaaaatata ctccatagta ccggatttta cgcattgctg ggatgtaata 32100 aatgtgtgat attattattt tgttactgca gtgaaattgg gttggttcgt aaattgaggt 32160 ataagcttgt taaacaaaat ggaagagaga ctgataatcg tagtaaatga accaataaat 32220 ggaaatgtat ttgacccaga aaatcaaatg atttcagcaa agagagattg gaggcaaaaa 32280 gaagaaaaag aaaaaagaaa atggccaacc gagaagaaga agaaaatttt tttagcggaa 32340 gagagaaaac attttgagaa atttaacgag gaacgagtaa aagagtaaag agaaaataaa 32400 taacaaaaga atatataatg aaagaattaa taatcaaaac atttacaatt taactctaaa 32460 attaccattt acctcttttt ctttttcttc ttctactata cttctatcca ctttactcat 32520 ctcttctctt gccttttttt tttttctctc tctctctctt tcttttctct tttctccttt 32580 ctctttttgc tgccctactc ccgctgccct gccgacgtcc tttaccctgt ttttcctctt 32640 cttcctcttt tcctcgtttt gctcccggaa aaacgataag cttttctaac gtgtttcctt 32700 cccctaacct gcaatcttca catttgcatc ggcaaggtag caggggcggt agttacgttg 32760 gactggggtg gctagattca tctttaaaat agtagggtca ggatgattgt accatagaat 32820 tgttttttgt cctctactct tatctaagat ttgaaggcat atctattgca aaagcaaaag 32880 tatctgaaac ttcgatgact gcgtattttt tcatataaaa cgatattgac cggcattgtt 32940 gagttgcgaa ttgcgtttgg aaaaccagcg gaaaaaaaag taggacatag caaattgatt 33000 gcttagcttt tgtaataaga agggatcagg gctgttgttg ttttcttggt ttagaaaaaa 33060 acagaatcaa aaataataaa gcaaaaaaga atattttgtt ctttttcctc cactccccat 33120 tttatttcac ccaacggact ttgtgtgaga gcgattatcg gttcgtctgt tattcaagac 33180 atactttgta ttatttgggt ctttctgttg cttgtgtgag tgtatctgtg tgcgtgggtt 33240 tttttgtgtg tgtgtgtgta tcttttgtgg tgtgtataat tagttatcgt tttcaatttg 33300 tttaatttta ctcttcttct tttaatttgg caatccactt tttctttggg ccattcattt 33360 ctatactata ctaaataccc tataccctct actttataat tttagtattc tttccttgga 33420 ttcaattatt gcttttcact ttaaaaaaaa aaaacaagag tcgataagca tttcattccc 33480 attttcttca tcattgatta gttttatttt atttataaat tctctatact gtcttgatcc 33540 ccttttttat ctgctttgga tttacctatt ttgaactcgt tccctacaaa cttttacata 33600 gcaagttaat tcttcctgct gtgtttataa gacatataga tttttataca tatattatat 33660 ttctgttcct tttctttttt cttcttcttc ttcctaattc ccctcccatt tttgcttctg 33720 cgtcgattgt tactgcgtac gttgcagcat actcttcatt ttcttctagc tgtcttttct 33780 tattctattt ttttattttt tgatacacga tgtcaattct taatgtcatc cgctcccatc 33840 acgacgtgga accacagaat gttgaagagg agcctccatt gaccgggcaa actatcgtta 33900 ccgaagacaa actagagact tctgccaaag acaagaaaca tgagtcacct agtatgtcgg 33960 aggatgaaga gggctcggtg gaaaatgttg atgcttggga tctcacaaag gctcttatgt 34020 ccattgatcc caaccatccc gctcatcctc ataaatggcc cttgtggaaa aagttgtttg 34080 ttgctaccgt ttacacattt ttagaggtat atgtcatttg gtcatccacc gcctgtatca 34140 acttctttga tatttatcaa actaattggc attgcagtat tcaagtctcc tatcttgtac 34200 aaagtctttt cattgtcggt aatgcttttg gtcccatgct tttaggtccc atgtcggata 34260 tttttggtcg taaatgggtt tatgttggct ctctaattct ttatattatt ttccaaattc 34320 cccaagccct tgcttataac ttacccatga tggcaatcaa cagtgctatt gctggtgcct 34380 ttggtagttc tgctctcgct aacgttgcaa gtagtatgtg tgatatcttc actcctgaaa 34440 ccgtcggttt tggtatctct ctatttgttt ggggtgcaaa tgcaggtgcc tctattgggt 34500 cccccattgg tgaggctctt tatgatcatt ggcgttggtt ttactggatg aatatgattg 34560 ttggtggttt ctttgtaatt ctttgcgtat tgtgtcctga gaccttacct gtcatcaaca 34620 tcatgaacta ttcttctact actggagaaa aaaccgttca agtctctact cttgccaaag 34680 ctaaatcagc tgtagttcgt acaaaatttg tcttatccac cgcttttaaa cttttgtgta 34740 cagagcctat cattatggct ttgggtttgt ataacggctt tgcgtatggt ttgattttcc 34800 tttacttgga tggactgttt cccgtatttg tcgacaacta caaaatggga tacatgggtg 34860 caaatctcac ttatttgaac tttttggttg gtgtcaccat cgttgttatg cttcaaccca 34920 ttcaaaattg gctttatcgt tgggataaaa ggcgtcatgg aggtgtagcg cgtccagaag 34980 cacgtttctt gatttctctg cttaccgttt ggtttttccc agcaggcttg ttttggttcg 35040 cttttacttc agatggccga atttcttggg taagtccttt aattgcaggt ggtgttttag 35100 gtgttggtga tcctcaactt tggcttgcca tgattaacta tattactgat tcctacccat 35160 cggttgctgg ctccgccatc gctgctttca ctttaccaag ttttgctatt gctgctgttc 35220 ttgtacatct tggtattatc atgtttgaca atatgactac cacttgggcc atggcaactt 35280 tggcttttat tagtttgtcg cttgtggcca cgatttatgt tatttacttc tttggtcatc 35340 tcattcggaa acacagtcga cttgccgtta ctcaacaagc attacaagaa gcacatgatg 35400 ccaaggtttt acctgaagtg tagtgtttat tccatcattt ctccctttta tcattcatgt 35460 tagcatatgt aaaagttgtt atgttcgtat tgatatacac tcatccaact ttccttttac 35520 tgtgaacacc cgattatgta tgtacccctt cttttttggc aatatgcatc tacttctttt 35580 tgtcgataat tcgctattct tttctacctt ttttgtacta gttattgttt actaattgaa 35640 atctgtccta ctacagctat tgcagttgaa attacagtcg tcttaaaaaa tatagcttaa 35700 aaagttacgt ttattaaaaa gctgccttat agcactcgta atttttagtc gcacagtagt 35760 ttatacttgc aaaatagcaa tgtttaatag attatgtagt attatattcc taatcggcta 35820 atgatgactg gaaatgcgag tttcaatccc catgtattct ggacgaccga aacagcattg 35880 atggttttag cgtagaccga ctgtgtagat gtattaactt cagacactga gctgacctct 35940 tctgctctac attgtctttc cagaacggcg atcataatcg atgtcaaccg attcatcgac 36000 aattcccgaa ttccaagtag caatagatag catgtcgttt ctttgaacat gtagttggaa 36060 aaattaacac aatttataaa ttacatacat atagtcaaaa cacaacctgc gtctcttttt 36120 taacatacaa tatgtccagc actgaacttt cagaaaagga tttagcttat ctacgagagg 36180 ccatcaaagt ttctcagcaa gctcgtgatg aaggtcaaca tccatttgga tgcattattg 36240 ttgatgaaaa tgacaatgtt attatgtctg cgggaaatcg agttccagac ggggatgtaa 36300 ctcaacatgc tgagacccgt gccgtaggtt tgattacgaa gacaagaaga gaccttgaga 36360 agtgtactct gtataccagc acggagcctt gtgccatgtg ttctggtgct atattttggt 36420 ctggtattcg ccgaatgatt tttggcttat cgaacgaaaa tttgattaaa ctgacacaga 36480 aaagtggtga gtgcccgcct ttatacatta attcacgaga tattcttgga gctgcctctc 36540 atcctattga ggtggtgggt ccctacattg aagatgaagc tattatccct cataaaggct 36600 tttgggatgg aggaagatag ctgcttcaat ctcatatgtt aatgtcaaaa gcatattcct 36660 tgaaactttg ctaatacgtc cacacgtttt atcgtttctg ctagctagta gggtagactc 36720 tgttcaatgt ttatgaacaa atgtaattat tctatttcct ccaattgaac ttcttagtaa 36780 ttaaaactgt aattacttct atgctcaaat tgcaatatat cttcgtgtac aatatttact 36840 ttcttgccat ggtatacaaa tatcaatacg ggcctcaggc aagttacaag attaattcgt 36900 tttataaatt aaaattttta atgccgcttt tgttcaaccg aatgcctatg atcctattca 36960 aaatcattag tgaccaaagt gggttttttg ctcatatcac caaaaagaaa gtgtataatg 37020 gtatggtaaa tataatctga ctggactaaa tttctcagtt tattgctaaa tcctcctaga 37080 aaatggaaac agtttagtgt ttattacaca cgcgaaaatt atccaaaaaa tgaaggtctt 37140 cagcataact cttgttggga tcacttaacc ctactttcac gaatcaatca tttaccaaga 37200 ataatcattt tttttgtgct atttaatatt tatttactaa aaagtagata aattaattaa 37260 atcaaatgac caagtctcaa aacaatttca aagcataatt gcttttgcat tcttacttga 37320 actcttaact caagcgcgca caattttatt acattccaca tattaaaagg aagtgtcact 37380 cctttttgca acagagtagc atcaaactac aactctaaga gatttattac ctactgtgtt 37440 tctttcgggc gcactcaaag tcggcaaatt tttatgggga attaacatat tacaccgcga 37500 tgaagataac aatatcaaaa atcctacatg aaaatgataa gacctaatct tatcaaagta 37560 ttctgacttg ctccgcaata aaggagatcc ctgttttggg gttactcaaa gtctcagaaa 37620 ttgacaacgt tatcaaagtc caggagatgt tgggttcttt tagtgatcca tttccaaaca 37680 aattaattat aaccgtcttg acacaattgt tgctaaagtt ttaatttatt tttttctgta 37740 atacaaacac ttaatcgata ctgggtttga aatgggatcc ttagaagtac cgtgcattga 37800 cctttctgaa aatgatactt ccattgtcgt gaaagaattg ctcgatgctt gtaaaaattg 37860 gggattcgtt tctttgaaga atcatggaat tccgctagat gaaatagatc gtacatttaa 37920 gcttgcagac aaattttttg atattcctgt agaagaaaag cagaaatatt tgttcaaggg 37980 tggccgatta catagtggat acacagggca ttttggtgag aagttagata tggaacacca 38040 gtcgagaggt gatttgaaag aatcctatga tttagcagga tttccagatc 38090 //