ID SPCC895 standard; DNA; FUN; 26453 BP. XX AC AL035247; XX SV AL035247.1 XX DT 18-JAN-1999 (Rel. 58, Created) DT 04-FEB-2000 (Rel. 62, Last updated, Version 2) XX DE S.pombe chromosome III cosmid c895. XX KW cytoskeletal organisation; ion transporter; KW pre-mrna splicing factor rna helicase; snare complex protein; KW spindle assembly checkpoint protein; spindle pole body-associating protein; KW SUA5/YRDC/YCIO/YWLC family; syntaxin like; translation initiation protein; KW trp-asp repeat protein; WD domain. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-26453 RA Wood V., Rajandream M.A., Barrell B.G., Lucas M., Gaillardin C.; RT ; RL Submitted (14-JAN-1999) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and INRA - CBAI, Laboratoire de Genetique Moleculaire RL et Cellulaire, Route de Thiverval, F-78850 Thiverval Grignon, France XX DR GOA; O59767; O59767. DR GOA; O59768; O59768. DR GOA; O94530; O94530. DR GOA; O94532; O94532. DR GOA; O94534; O94534. DR GOA; O94536; O94536. DR SPTREMBL; O59768; O59768. DR SPTREMBL; O94530; O94530. DR SPTREMBL; O94531; O94531. DR SPTREMBL; O94533; O94533. DR SPTREMBL; O94535; O94535. DR SPTREMBL; O94536; O94536. DR SWISS-PROT; O59767; MAD3_SCHPO. DR SWISS-PROT; O94532; FOR3_SCHPO. DR SWISS-PROT; O94534; AL14_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c895 is overlapped at its 5' end by cosmid SPCC1795, CC EM:AL022598 and at its 3' end by cosmid SPCC825, EM:AL122011. XX FH Key Location/Qualifiers FH FT source 1..26453 FT /chromosome="III" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c895" FT /map="IIIR" FT CDS join(1..313,370..1243) FT /codon_start=3 FT /db_xref="GOA:O59768" FT /db_xref="SPTREMBL:O59768" FT /label=SPCC895.01 FT /note="SPCC895.01, len:>394, SIMILARITY:Pharbitis nil, FT Q9ZQT4, h+/ca2+ exchanger 2., (435 aa), fasta scores: opt: FT 863, E():0, (35.8% identity in 408 aa)" FT /partial FT /gene="SPCC895.01" FT /gene="SPCC1795.02c" FT /product="ion transporter; proton/calcium exchanger" FT /protein_id="CAA22837.1" FT /translation="NFPAQDRHERAPLLGSEYDHSMARQLSLLNVVGMTKSVLMSSYFN FT LMLVFVPIGLIAGWFEWNAKSVFILNMLAIIPLASLLSFATEQLSIISGPTLGALLNAS FT FGNAIELIVGVLALKRGELRIVQSSLLGSILSNLLLVFGMCLVTTGIRREITTFNITVA FT QTMIAMLALSTATILIPATFHYSLPDNANSENALLHVSRGTAVIVLIVYVLLLVFQLKT FT HKHVCHDPSEVEEETEPRILGLRSSIAMLAIVTVFVSLCADYLVGSIDQLVEEVNISKT FT FVGLVILPVVGNAAEHVTAIVVSYRGQMDLALGVAIGSSIQIALFLAPFLVIVGWIISQ FT PLTLYFESLETVILFVSVFLVNYLIQDGATHWLEGVQLLALYAIVVLAFFYYPQ" FT misc_feature 1..2325 FT /note="nominal overlap with cosmid SPCC1795, EM:AL022598 S. FT pombe chromosome 3" FT misc_feature 314..319 FT /note="gtaaga, splice donor sequence" FT misc_feature 352..369 FT /note="ttaacacgttgtgtacag, splice branch and acceptor" FT misc_feature 768..1181 FT /note="Pfam match to entry PF01699 Na_Ca_Ex, Sodium/calcium FT exchanger protein, score 3.40, E-value 0.0043" FT CDS 2115..3047 FT /db_xref="GOA:O59767" FT /db_xref="SWISS-PROT:O59767" FT /label=SPCC895.02 FT /note="SPCC895.02, len:310, SIMILARITY: to the N terminal o FT f Emericella nidulans, O59901, spindle assembly checkpoint FT protein slda, (1216 aa), fasta scores: opt: 425, E():1.7e-2 FT 0, (33.5% identity in 337 aa)" FT /gene="SPCC895.02" FT /gene="SPCC1795.01c" FT /product="putative checkpoint protein kinase" FT /protein_id="CAA22838.1" FT /translation="MEPLDAGKNWVHMDVIEQSKENIEPRKAGHSASALAKSSSRNHTE FT KEVAGLQKERMGHERKIETSESLDDPLQVWIDYIKWTLDNFPQGETKTSGLVTLLERCT FT REFVRNPLYKDDVRYLRIWMQYVNYIDEPVELFSFLAHHHIGQESSIFYEEYANYFESR FT GLFQKADEVYQKGKRMKAKPFLRFQQKYQQFTHRWLEFAPQSFSSNTNSVNPLQTTFES FT TNIQEISQSRTKISKPKFKFSVYSDADGSGKDGQPGTWQTLGTVDQRRKENNISATSWV FT GEKLPLKSPRKLDPLGKFQVHCDEEVSKE" FT CDS complement(3369..4595) FT /db_xref="GOA:O94530" FT /db_xref="SPTREMBL:O94530" FT /label=SPCC895.03c FT /note="SPCC895.03c, len:407, SIMILARITY:Saccharomyces FT cerevisiae, SUA5_YEAST, sua5 protein., (426 aa), fasta FT scores: opt: 1012, E():0, (51.3% identity in 419 aa)" FT /gene="SPCC895.03c" FT /product="similarity to yeast translation initiation FT protein Sua5p" FT /protein_id="CAA22839.1" FT /translation="METKIQTVDTRLISFEKPSNDSEHPFEHTRVSIPPSETRSALENA FT ANILRNTDYPVAFPTETVYGLGADARRTEAVLSIYKAKNRPADNPLIVHVASLDQLRRL FT LLSAYPKAKSEVKNQAHDSEEIIPKVYLPLIKKFWPGPLSILLPVVDEANPPVSPIVTA FT GQKTFAVRMPQHPVALALISISDSPLAAPSANASTRPSPTLAKHVYNDLQGKIPLILDG FT GACGVGVESTVVNGLCDPPVILRPGGISLEEIQSSGGAWERTKVFVAKKSDMETDFIPQ FT TPGMKYRHYSPTAKVLLFVNYTESDAYGVFEKYLSEQGITKEKQKIGVLCSKRWNEESF FT PSHCPFVFLHMGRDGHEITKNLFAQLRDLDLQGVDFVLVEGVSEENEGLAIMNRLGKAA FT SVVFEGPSH" FT misc_feature complement(3855..4457) FT /note="Pfam match to entry PF01300 Sua5_yciO_yrdC, SUA5/yci FT O/yrdC family" FT CDS join(complement(6572..6691),complement(6140..6374), FT complement(5447..6051)) FT /db_xref="SPTREMBL:O94531" FT /label=SPCC895.04c FT /note="SPCC895.04c, len:319, SIMILARITY:Saccharomyces cerev FT isiae, UFE1_YEAST, ufe1 protein., (346 aa), fasta scores: o FT pt: 207, E():1.8e-05, (23.9% identity in 309 aa)" FT /gene="SPCC895.04c" FT /product="putative snare complex protein; syntaxin like" FT /protein_id="CAA22840.1" FT /translation="MTSRTNEFFGLTKNGDIDAANIPLKRISYTDPFLAEGYRIHETIV FT NLLVFLKKIRGAYLKDRTFSNVQRLSKPLMECSLEELSKLELDEVQRDEIEHEVSSAIS FT SCIHQIAKLQEIVKEQQSQIPKKSGWLQGLRDPSKLSKKETLVAHHSSVLWYLQSELSD FT VSSVLYHLQDLRLKRGQEKRNIASDFLTKNPTDENSAVEIPESELQTFFTQQQLQELEQ FT ENDVLLQEFEHTMERLRDTGKSLADITRLQSEISAQLSIQSSAAEKLYDDALNVMDSLS FT GGNQQLIKAKSRSSRTARLLFCIFTVMGLLLLSLDRIV" FT misc_feature complement(6052..6067) FT /note="ctaattgcatgagtag, splice branch and acceptor" FT misc_feature complement(6134..6139) FT /note="gtaagc, splice donor sequence" FT misc_feature complement(6375..6387) FT /note="ctaacgttagcag, splice branch and acceptor" FT misc_feature complement(6566..6571) FT /note="gtaagt, splice donor sequence" FT CDS 7557..11942 FT /db_xref="GOA:O94532" FT /db_xref="SWISS-PROT:O94532" FT /label=SPCC895.05 FT /note="SPCC895.05, len:1460, SIMILARITY:Saccharomyces FT cerevisiae, BNI1_YEAST, bni1 protein, (1953 aa), fasta FT scores: opt: 672, E():1e-20, (24.3% identity in 875 aa)" FT /gene="SPCC895.05" FT /product="similar to yeast cytoskeleton control protein FT Bni1p" FT /protein_id="CAA22841.1" FT /translation="MASKMPEGSPPTSRSIQSRNSSYSTSSNERIGTPSTISLSENSDL FT SKLQSTNDFESREDLSLTSDDNNDPEYVMCYNTVYHQKTKINDKLLSETEQLRKIYPLE FT SRVFPKPTIVKEITNERTKRYTFYDDDAPLTNQHTVLDEATYNRILKRIDFFIEKVVEV FT PPTYHFLSLLNVQLRIQPIWWMDEFAERNGIESLLSALRNLGHYPERASKTPLESQIIQ FT SLFHCLNSENCRRRYQSSAKCSVPGFNALGTIAETVLSKSLNSARMATFLLKFLCNKKG FT LSYFKAVIRAFEWLVEQKLSKTRFSAWMHSFNDVITGVRVCADSSPQAIVHMDEFEDTD FT CLIDYLVATLALIRDLCAAPPDLQLRCALRHELLSAGLQKAIDSLLKWRNRHVRDALQL FT LIKEHNADARRFRSGSDVNNVDRKCVKKQMNYREESHTPHGNTTRKTSTPVSNNRPTTP FT EQQAVWDVFQRIYTRFTGSEGSKESFIKLLEYFVTEPDNGKIQKSMQLLTHTLEALEGF FT KTAKADTNVGLTILSQRLLDKLGTAEEIAEYKTKYNGAMLENKHLKEQVESMLSQLNVG FT PRDPMQFLKKQLDELKAELNLRDNLLASMQREFETRYRAQIQAYNKLQSQMEHVQNSNE FT QHLQPGLLNKVSKSFDSVHRRNLSQDSLDAMTEQFSYHVEPNILSGSGIPVRVHTPSKT FT EDLDESFSGSEISSSPSPLLPDVSDTVEEQQKLLLKSPPPPPPAVIVPTPAPAPIPVPP FT PAPIMGGPPPPPPPPGVAGAGPPPPPPPPPAVSAGGSRYYAPAPQAEPEPKIDETSLTE FT EQKIQLEEARKQRKAADDAARAAIEKYTSIPSLRDLHKPTRPLKRVHWQRVDPLPGPNV FT FTKFCLNFDITAKVFIDNGLLDFLDEKFDNTPREDFVAVEISDQRSSLLPDTVEQNMAI FT ILRSVSNMPVEDLVQKFLVEPDFLPASILYFDRASLASTNAYTDPFIPYSTDYTKKNPK FT EPTADVNSLSYFEKFFVLFVVNLRHYFQERMKALKFRSTLFGDLEILEVRMKEVIDTSD FT SIMEDKNFAEFFQVLLIIGNYFNEPYDRASAFSLYMIYRLETLRDSSSALTLMHYFDEI FT IRTRFPELLQAESTFKKIQSVSGYNIDAMVAGVDGAYDEFCDFQTSLKDGALSKCDQHH FT PDDKAYDILSEWLPEAKERIRNIKKLKTDMLTKLENTVKYLCEYDSIDKVRNSFFKNLN FT SFYEMYSIAKAENEERFEKEKRRIMSEDRDKLIRGRQKTSIVAKYRNKRELPEDSDDKQ FT DTASKDKNSLETIDEKMEDASKIEGDAKTGDDNEMEDLDKMEDLEKPDYAEEKDPYITV FT MSELRSRIQNVPKRTVTVYSDEGVATLEPGAQGDDVVDKAKMILEKMEGHSQLLTSSAN FT PDEEVLRAKLKAAERLQKPAIPRTRRKGHTEPKSAKSLLAELTNGSNASNLVENDRQKQ FT " FT CDS join(12900..13016,13096..14925,14968..15303) FT /db_xref="SPTREMBL:O94533" FT /label=SPCC895.06 FT /note="SPCC895.06, len:760, SIMILARITY:Saccharomyces cerevi FT siae, YG4C_YEAST, hypothetical 89.4 kd trp-asp repeats cont FT aining protein in pmt6-pct1intergenic region., (788 aa), fa FT sta scores: opt: 685, E():0, (35.0% identity in 792 aa)" FT /gene="SPCC895.06" FT /product="hypothetical trp-asp repeat protein" FT /protein_id="CAA22842.1" FT /translation="MFQYEALHVGCNRIPTAATWSSNLGLIYGAERLIAVADPFKEINY FT LMAGHSGRINCVCELATNSEYRSPFILSGASDKTLRLWQLEEEYFTCIKTIELEATVNC FT LCVNENLVVCGCSNSSCIVYSWNAEQRNLTEISRFTCSEIIPLEFAIVKLDHGIILTVC FT GSSKKIMVYGSDSAISSFKLKAVLRGHLDWVRTLSFKKTSGSTATLASGSQDRYIRLWN FT ISLWGSEDEKVSEEFFESVLSNKPVRFTLGKIDLKIVFDALLMGHEDWVMSVDWHPTKE FT MILSSSADSSMIVWEPDTNTGIWVVTGRMGEMASSHGSTTATGSAGGFWGGLWNPNGNC FT VVCWGRTGGWRLWKQDAGQWLQLPSISGHTKSVKGVAWDPEGKFYLSAGTDQTTRLFAR FT FKKDNAWHEMARPQIHGYDLTSISCMPSRIGFLSCADEKVSRVFKFPKTIVRLLYRLCD FT TNIGEESLPDAANVPLLGLSNKATTASETGTVNAEEVQTPVADVIGSLNHPPFEEHLQR FT LLLFPEVEKLFGHGYEVYACAISNNGNIAATSCKSQTPEHAVIRLYETQSWNQQQVLKG FT HSLTVTTIKFSPDDRYILSAGRDRLVCLHEQAENLLDYNNFASIKAHSRIIWDASWAPK FT EMGYFFATASRDKFVKFWKINDNKKICDVAALQFSDAVTAVDFAPFFHNDELLLAVGTE FT AGKIFIWRCPRENLTKWYPTRLPDHMAPMESINQILWKPTFETMGLYSLLIAGEDTSVR FT LLNVTLG" FT misc_feature 13017..13022 FT /note="gtaagt, splice donor sequence" FT misc_feature 13081..13095 FT /note="ttaaccaataattag, splice branch and acceptor" FT misc_feature 13099..13230 FT /note="Pfam match to entry PF00400 G-beta, WD domain, G-bet FT a repeat" FT misc_feature 13519..13644 FT /note="Pfam match to entry PF00400 G-beta, WD domain, G-bet FT a repeat" FT misc_feature 13750..13866 FT /note="Pfam match to entry PF00400 G-beta, WD domain, G-bet FT a repeat" FT misc_feature 14056..14172 FT /note="Pfam match to entry PF00400 G-beta, WD domain, G-bet FT a repeat" FT misc_feature 14680..14796 FT /note="Pfam match to entry PF00400 G-beta, WD domain, G-bet FT a repeat" FT misc_feature 14839..14928 FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 20.67" FT misc_feature 14926..14931 FT /note="gtgagt, splice donor sequence" FT intron 14926..14967 FT /note="confirmed intron" FT misc_feature 14956..14967 FT /note="ctaactatttag, splice branch and acceptor" FT CDS 16189..18618 FT /db_xref="GOA:O94534" FT /db_xref="SWISS-PROT:O94534" FT /label=alp14 FT /note="SPCC895.07, len:808" FT /gene="SPCC895.07" FT /gene="alp14" FT /product="spindle pole body-associating protein Alp4p" FT /protein_id="CAA22843.1" FT /translation="MSQDQEEDYSKLPLESRIVHKVWKVRLSAYEECSKSFSLSADGSD FT NCFELWNNQSELWKSVLTDSNVAAQEAGTAAFVAYCRFSDPSHLLKAREISVLSISEKC FT LTSPRAGTRENALEALMLLVEADSAAPVIESIIPSLSARSPKVIASNVAAIASLVEQFG FT AKVIPSKMIIPHISNLFGHADKNVRKEASRLTVNIYRWTGDPLKDLLFKDLRPVQTKEL FT ESLFAELPTEPPKQTRFLKSQQPTSEPNVETQVEEQPALENEESEPEPSDDQFDLVEEV FT DVLPNVDPNLETLMASSKWKDRKEALDKLLPVLSQPKIKDNDFFNLVAILTKSVSKDAN FT IMVVINAAHCIQAMAKGLRSNFSKYASTSINALLERSKEKKANVIESLSSAMDAVLATS FT SLDDLAELIASFAGNKNPQIKSSCFSLFSRSFSNMTSLPSKFTVDTCAKACVPGVSDTF FT EPVRSAAAEALGVLMKLVGERAINQYLSPLDDIRKSKIRSFYETATVKAKAPTKKSKVK FT PSKQEESKVVVPSNAKAVKKSVVPSSPVVPSPRKATNKSLSMDVSKGNAFENGPLLPRP FT TTRPVSRGLSRGTSSSLQQKVKASTPLNSGALNETVQNLKNMELDDPAPQPAKHSRVDR FT YEHPKVLEDNDSTISSLESLKRENEELREQLKVEHEENISMQKQLSELKGELNTLRSAR FT KASPIGDRKPAFMRRANTDFLELSTSPSFQRSVREFEPTRPKLYSSIDVNQRSPLASAK FT TNGNFTFHAELPRSPFSSRANNINPDWTKAIDLAAKLKQKITEMKQTDQRHQGLIH" FT CDS complement(19075..20547) FT /db_xref="SPTREMBL:O94535" FT /label=SPCC895.08c FT /note="SPCC895.08c, len:490" FT /gene="SPCC895.08c" FT /product="hypothetical protein" FT /protein_id="CAA22844.1" FT /translation="MDNSRDKIHILGAVSDTFQEVQHPCSILKYKVYFVTTDTFYCKYL FT TASFTGLKKFPTERQLPLECHFNHIDWDLGNNFKVKEGVFYTFDIIAPLPRCTPRTIVT FT QEGSISYKLTVKLYTEDDCRMPKSANVPVVVPFTLNPDRIPESQHIRYGAPLNDACFTS FT LSMKSSKYSFLTAFFKYPQQCYKGPGCVCPLLIDLESEDADVLSSTPGSAGTDDPHIDP FT IAINSQDSQFIFQDRLPRLSNDCDMKGRSSLSRTSSPVVEKKLKRYYIRVLLVQSITFF FT LFNDAFRNSITVLFEDGKWSPPIVPGLHSRVEFTIPVNDLIHGSCTENPHLLVRHSIYV FT SIHSREPSSLSRKLAPPFLRTHKAKSNSLFSMKRPSSSSSSLSGSWHGDTENSVKQSLA FT SPSEASLPNLSKYSRKNAKKLNEWLDSLDFKLPIYLFHRKLESELSHLPPYSPYRDSYF FT YLEDDDGDADTPSTASLDYFSNISPPDFLNKA" FT CDS join(complement(25455..25718),complement(25195..25383), FT complement(24535..25135),complement(22473..24493), FT complement(21521..22429)) FT /db_xref="GOA:O94536" FT /db_xref="SPTREMBL:O94536" FT /label=SPCC895.09c FT /note="SPCC895.09c, len:1327, SIMILARITY:Saccharomyces cere FT visiae, PR43_YEAST, pre-mrna splicing factor rna helicase p FT rp43, (767 aa), fasta scores: opt: 806, E():0, (31.2% ident FT ity in 788 aa)" FT /gene="SPCC895.09c" FT /product="putative pre-mrna splicing factor rna helicase" FT /protein_id="CAA22845.1" FT /translation="MGSKGKKGKSSEVNLETSKNKEKNIKGKKKNSLDPIEKNKQETAG FT LQTTSRPTAKQLVGGSSWTGKIPVVLLNEHCQRSKWEKSDVKVRQTKSKNYIFTSVVLA FT KKDPKNPSILDHVSLIPPKSYYENGYFPEKETLVEARNVGAVYALHRIMSHKSLQHALP FT PEHRNIWFDMEKQKKEELKNKHSWLYNEDPFKAAKELQAARASSAAKPPPKASQKNEKV FT SLTSIKNTSLSHFSKFNFKYALPIHMSLENRRSLENLFRNMNTWDILEDTKNLEPDTSI FT VNDLISLGFRDIHAKEACQYCVSLEDALEWLIIHVPEDDLPTRFLPSDYTTGISVQNLN FT SANLAIHYNAKRISETGYSFDLCFSTLQTFENNIQISSEYLQQHLIGESFDGNISLEPN FT STEWDDDVSALQSILDNKVSKIENGCRVRIDYPTSEFGELFVDFRRPARSYPAHIPLMS FT LSSTKRMASYIKLSILKKMVVYAMDLRGECMLSWLYNHLQENIEDFLQNIGSLLNISAA FT TIGVSLSSQNKSAPTAKKNNSFKPKLFRRSRELSEKLCNNWSERVKSPSYQLKVREREK FT LPAWESRRKIMDAIQHSQVVVISGETGSGKSTQVVQFILDHYLSSGEKDLQTVVCTQPR FT RISAISLAERVAFERDTTVGKEVGYSVHGEKSISKETLLEFCTTGLLLRRIQQHGLGFL FT STLSCVVVDEVHERSIENDILLTLLKLVISRIPNLKVILMSATVNSDTFKYYFGNAGHL FT HIHGRTFPIKDYYIEDFAPKLNEDDDEEDVPRRKKKEYEIDYHLISRLVSSIDAELGSS FT SGSILVFLPGVSNIARCIREIKSKDGSKFEVLPLHASLNTSEQRRCFKTYTKRKIICAT FT NIAETSITIDDVVAVIDSGRVKQIDYDVERDLVTFKETWASRAACQQRRGRAGRVKKGI FT CYKLYTRGFEEKGMLGQTPPEVLRTALSQVCLNVVPLVKRFSSAGNSVNQGSIKKFMNS FT LIDPPNDATVDLALKKLIQVGALTVSEDLTGLGEYLVSLPIDLKLGKLLVFGSIFGYLE FT PALTITAILSTKSPFLGDDEAREIRSKQSQGWGDVLADARVYHNWLEILETRGVKKTVQ FT WCEEMHLHYTTLQQIRQNRNELSEAAQLLELTTKKLTGNFDWYSTENLTVLSTLIAAAL FT SPNVVKCVYPDKKFVASFSGSLEMEQEARLTKFYDQNNQRLFIHPSSTMFVNSPNASRC FT TFVAYEQKVETTKPFLRNCTPINTYGMILLGANDILIDPLGKGLILDQAYCIKAWPKVV FT ILLKMLKRCLDASLHERLESSSGLNYESEIHQCIRTLIAGNGV" FT misc_feature complement(22430..22444) FT /note="ctaatataattttag, splice branch and acceptor" FT misc_feature complement(22467..22472) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(22767..23066) FT /note="Pfam match to entry PF00271 helicase_C, Helicases co FT nserved C-terminal domain" FT misc_feature complement(23727..23750) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(24494..24507) FT /note="ctaactattaacag, splice branch and acceptor" FT misc_feature complement(24529..24534) FT /note="gtatgt, splice donor sequence" FT misc_feature complement(25136..25149) FT /note="ttaatttctaacag, splice branch and acceptor" FT misc_feature complement(25189..25194) FT /note="gtaagg, splice donor sequence" FT misc_feature complement(25384..25401) FT /note="ctaaaatcttctaaacag, splice branch and acceptor" FT misc_feature complement(25449..25454) FT /note="gtaagt, splice donor sequence" FT misc_feature 25929..26453 FT /note="nominal overlap with cosmid SPCC825, EM:AL122011 S. FT pombe chromosome 3" XX SQ Sequence 26453 BP; 8262 A; 4846 C; 4918 G; 8427 T; 0 other; ttaattttcc cgcccaggat agacatgaac gagcccctct cttgggatca gagtatgacc 60 actctatggc tcgtcagttg tcgcttttaa acgtggtcgg catgaccaaa tctgttttga 120 tgtctagcta ctttaacttg atgttggtat ttgttccgat cggcttaatt gcaggatggt 180 ttgaatggaa cgctaaatct gttttcatac ttaacatgct tgctattatc ccccttgcat 240 ccttgcttag ctttgctact gaacaactct ctataattag cggaccaaca ttgggagcat 300 tgttgaatgc taggtaagat tcctacttta tcgtcttctt ttgttatttt attaacacgt 360 tgtgtacagt tttggaaatg ccatcgagct cattgtaggc gttcttgctt tgaaaagagg 420 agagctccgc atcgttcaat cgtcccttct cggatcaata ttatccaact tgcttcttgt 480 ttttggaatg tgtctcgtaa ctactggtat tcgtcgtgaa attaccacat ttaatatcac 540 tgttgcacaa actatgattg caatgcttgc tttatctact gctaccatat tgattcctgc 600 gactttccat tacagccttc ccgacaacgc taatagcgaa aatgcgcttc tccatgtctc 660 tcgtggaact gctgttattg tactcatcgt ctatgtttta cttttagttt tccaattaaa 720 gactcataag catgtctgtc atgatcccag tgaagtggaa gaagaaactg aacctcgaat 780 tttaggcctt cgttcatcca ttgccatgct tgctatcgtc acggtttttg tttctctttg 840 cgcagactat ttagtaggtt cgatagacca attggttgag gaagttaaca tttcaaaaac 900 tttcgttggt ttggtcatcc ttcctgttgt aggaaatgct gccgaacatg ttactgcaat 960 cgtggtatct taccgaggac aaatggattt ggctttgggt gttgctattg gttccagtat 1020 tcagattgct ttgtttttag ctcccttctt ggtaatcgtc ggatggatca tctcccaacc 1080 tttaacactt tactttgaat cattggaaac agttattcta tttgtgtctg ttttcttggt 1140 taattacttg atacaagatg gtgctactca ttggcttgaa ggtgttcaat tacttgcttt 1200 gtatgcgatt gttgttctcg cctttttcta ctaccctcaa taaattttgt cgttccctcg 1260 ctagttcctt attatgtcta ctcttatgtg cttgatatac tctcttgatt tctttgtgtt 1320 ttactttacg aaactatcat accgaactta ttgatttctt atttttttat actagatttt 1380 tttttttttt ggtttctgtt acaaggatat tttgcagact tattttttag tatgcaagtg 1440 ttaaattatg cagaaatctc ccattttcgc aatgactaca caactctaaa tttctattgc 1500 aggtcaagcc aatatctgct tgtttacagt agctttttaa gtcgctcatt cttcagtctc 1560 agtttcatgt gtcttaccag ctatgaaaat agaaaattaa tttttgaata aactcttgta 1620 aatcgttgtt tataaatctt cattttgttt atttttatta gttgttttgt aggttgtgtt 1680 ttacatgatt taataataca agccattagt atgtgaagtg gttaatttta attcttcttc 1740 tgtttctgta tattcgaaga aacagaaaaa acttcttatc tctttcattg gactcttcca 1800 ggcgtaagta tgataccctc ccccagcgtc aagttggcac ttaccttcta atttacgcac 1860 aatctttcat acattcctac tcttgctctt tgagtgttga cacttttaat tttatacaaa 1920 agctttcagt acaccttcta ttaaactata tactggctat tttcgttctt tcaatagaat 1980 tgtacttgtc taaataaact ttccaatact actacactca catctccttc tttgttttat 2040 ttattttcat ttagtggaag gtatagggtt ctctagaaaa ggtttactaa ttttttggaa 2100 gacattgact acaaatggaa ccattagatg ctggcaagaa ctgggtgcat atggatgtca 2160 ttgagcagtc caaggaaaac atagagccta gaaaagctgg tcattcagct tctgcacttg 2220 caaaatcttc gtcgcgaaac cacaccgaaa aagaagttgc tggtctgcaa aaagaaagga 2280 tgggccatga acgaaaaata gagacgagcg agtctcttga tgatccacta caagtttgga 2340 tcgattatat taaatggacc ttggataatt tccctcaagg tgaaacaaaa actagtggac 2400 tggtaacatt gttagaaagg tgtactcgag aattcgtacg aaatccgctt tataaagatg 2460 atgttcggta tttacgaata tggatgcaat atgtaaacta tatagacgaa ccggttgaat 2520 tattttcttt cttggcacat catcatattg gacaggagtc ctcgattttt tatgaggaat 2580 acgcaaatta tttcgagtct aggggattgt ttcaaaaagc tgacgaagtt tatcagaaag 2640 gaaaaagaat gaaggctaag ccatttttga gatttcagca aaagtatcag caatttactc 2700 accgttggtt ggaatttgcc ccacaatcat tctcttcaaa tacaaattcg gttaatcctt 2760 tacaaacgac atttgagtca acaaatatcc aggaaatatc ccagtctagg actaaaattt 2820 ctaaacctaa atttaaattt tctgtttatt cagatgcgga tggttctgga aaggatggcc 2880 aacctgggac ctggcaaact cttggtacag ttgatcaaag gcgtaaagaa aacaacatat 2940 cggctacttc ttgggtaggc gaaaagttgc ctttgaaatc tccaagaaaa ttggaccctc 3000 ttgggaaatt tcaagttcat tgtgatgagg aagtatcgaa agaataaccg ataaagaaaa 3060 gatttaaagt attggcgtta ttagattaac aactattgta catcatgact cccggaataa 3120 gaaataggtt gaaacatgcg aattttaagg gttatacgaa cttaacataa agcatcttat 3180 ttatactacg atttgcagct tttttttata ttttactctc aaattaatta tagtcagcca 3240 taagttaatg aatatgatat aaataattct tttatagaca atttatcaaa ataataaaca 3300 gatagctcga taagtaatta cacctctata caagtaaagc taagacccct tagctataaa 3360 tattttaact aatgagaagg cccctcaaaa accacagaag cagctttgcc caaacgattc 3420 atgatagcta gcccttcatt ttcctcggag acaccttcaa ccaaaacaaa atcaactccc 3480 tgcagatcca aatctcgcaa ttgagcgaat aaattctttg taatttcatg tccatccctt 3540 cccatatgca aaaatacaaa cggacagtga gaagggaatg actcttcgtt ccaacgttta 3600 ctacataaaa caccaatctt ctgcttttcc ttagtgattc cctgctcaga taaatacttt 3660 tcaaaaacac cgtatgcatc agattctgtg taattgacaa aaagtagcac tttggcagtt 3720 ggagagtagt gtctgtattt cataccagga gtttgaggga tgaaatctgt ttccatatca 3780 ctttttttag ctacgaatac ttttgttcgc tcccaggccc ctccagagct ttgaatttct 3840 tctaaactta tgcctcctgg ccgtaaaatt acgggaggat cacaaagtcc atttacaact 3900 gtactctcca caccaacacc gcatgctccc ccatctaaaa ttaaaggaat tttaccttgt 3960 aaatcattgt aaacgtgctt agctaacgta ggagatggcc ttgttgaagc attagccgat 4020 ggtgcagcta acggcgaatc tgaaatagaa ataagggcaa gcgcaacagg atgttgaggc 4080 atgcgaacag caaacgtttt ttgtcctgct gtcacaattg gtgagaccgg gggattagcc 4140 tcgtcaacaa ctggcagcaa aattgagagt ggaccaggcc aaaacttttt aatcaacggt 4200 aaataaactt ttggaataat ctcctctgag tcatgtgctt gattttttac ttctgacttt 4260 gctttaggat atgcactcaa cagcaatcta cgtagctgat ccagagaagc aacatgtaca 4320 atcaaagggt tatcagcagg gcggttcttt gctttgtata ttgacaagac tgcttcagtc 4380 cttcgggcat cagcaccgag accgtaaact gtttcggtag gaaaagcaac tggataatcg 4440 gtgtttctca atatattcgc ggcgttctct aatgcagaac gagtttctga gggaggtatg 4500 gacacccttg tgtgttcaaa aggatgttcc gaatcattac taggcttttc aaaagagata 4560 aggcgagtat caactgtttg aatttttgtt tccattgtca aggaagaaaa cctaagtttc 4620 tggcttactg aggccaattt tgctataaaa ttgtaatact tcagcttgtt ttatgttaat 4680 tgatttagaa agaagaagct aaatgctgat agagagaagg gtgaagttga ttgctattat 4740 taagttgaag cgcatcattg ctggttgtcg actcttgcaa agtaagagaa ataattgttg 4800 aagatatatt taaaaactca agattatttt actctaaata cgaaaataaa atctcgtttg 4860 agaaatttta ctagagtagt gattgacgac gatctttact taaaatttga atttagctac 4920 agaggttgta aaaaagaaat gtaagcgcga caatgatttc acgaatgaaa agaacccact 4980 tactgttttt atttgtgggt ttttttttat cgtttctgtt atttggcagg gtaagaatat 5040 attcttccaa tacatccctt ttgactaagc atttagttaa tttgctaatg tccaatgcat 5100 caatctaaat tatatagctg aatgtttaac aaacaaattt gactttgaat taatcgagac 5160 tgattgtgaa cttctataaa cattcgatca tactagattt ttcaagctac aattttacca 5220 taatctattt catagtaaat ggccagaaaa tttttggaaa actaacgtac ccaagatgaa 5280 ttataaggaa tttttatttg ggcgtgcaag gaatggtcga aagaataagc ataaacatta 5340 tatttacatg agattataga catgaacttc acatgatcaa agaagaacga gtttcattcc 5400 tttgtcatta ttgttacaat ataaagtttc agaagaatga agagaattaa acaatacgat 5460 ccaaggatag caataaaagt cccataacgg taaagatgca aaaaagcaga cgagcggtcc 5520 gactacttct agatttggcc ttgattagtt gttgattacc cccagacagc gaatccatga 5580 cattaagggc atcatcataa agtttttcag ccgcacttga ttgaatagat agttgagcgg 5640 atatttccga ctgaagtcta gtaatatcag ccaaagattt ccctgtatca cgtaaacgtt 5700 ccatagtatg ttcaaattct tggagtaaaa catcgttctc ttgctcaagt tcttgaagtt 5760 gctgttgagt aaaaaatgtt tgtaattcag attcagggat ctcaacagct gaattttcat 5820 cagtaggatt ttttgttaaa aagtctgaag caatgtttcg cttttcctga cctcgtttta 5880 atctcagatc ttgtaaatga tatagaacag aagaaacatc ggaaagttca gactgcagat 5940 accacagaac agatgaatgg tgggcgacta aagtttcctt tttcgataat ttactagggt 6000 ctcttaaacc ttgcagccaa ccactttttt tagggatttg actttgttgt tctactcatg 6060 caattagcaa gcatgtccct gtgttttgtt tataatttaa gtaaacataa ttttaccagt 6120 attaaaattt taagcttacc tttcacaatc tcctgcaact tagctatttg atgaatacag 6180 ctactgattg ccgaagagac ttcatgttct atttcatccc tttgaacctc atctagctca 6240 agctttgaaa gctcctcaag tgaacactcc attaaaggtt ttgagagtct ttggacattt 6300 gaaaatgttc tgtcctttaa ataagctcca cgaatctttt tcaaaaatac tagaagatta 6360 acaatcgttt catgctgcta acgttagcaa tttgaactct ctgattagat atagaaagca 6420 ataacaaaag ttaatactgt caaaaattta aaccaatccc actcaataat taatcgtata 6480 ttatggtagc gcatctccac agtgatcaat tgagttgagg ttaaatttcc gattggttca 6540 ataattacag aaaactcgtc ctcaaactta caattctata tccttcagcc aaaaaaggat 6600 ccgtataact tattcttttc aaaggaatgt ttgctgcatc aatgtcgcca ttttttgtta 6660 atccaaaaaa ctcattcgta cgactcgtca ttcagaattt gagatgctaa gaaaggagaa 6720 atataaatcc cgggttaaat gaatttcaaa ttaacagaac agatgtttag aaaatggtag 6780 cattccatat ccccttatga atagtgacac ggtaaacgga attgagagac ttaaaggtgc 6840 tcgtaacaaa tgttcaaaaa agcaaaaaaa aatactccat tgtacgagtt ttgtttattt 6900 acttcaagtc gatgtctaca ataaatgaaa ttaagctaaa gtttcgcaat ttttgaagta 6960 tttagaaatg agctattttc aagtaaacaa acaaacgtaa ccagttatac acctcacaag 7020 aatggagcgc agtcaaattg tttacaattt ttgagttatt tttaaaaatt tagcttgaaa 7080 aaagttgttt gtgtccttta tctcgaagaa ataaggtttt tgttttgctg gtgttgaggt 7140 tgctatataa taacatggtt tgggcgacat aaattcatcc tttaccaacg ctcttcgaaa 7200 cgttaaattt gcatatttat caagcatttt attgcaataa ggctaatatt attaacttta 7260 attgatttta accttcagta tttgcttatt gttatacaat atacagtgat tacccctttt 7320 tctaaaaagc tgtactttcg catcacatct gatacctgcg ttcctttcaa ctttttaata 7380 taatcatcca aacgatttta aaatctggtt gacattaccg cggagcttta agctctgcat 7440 tacgatatat tttctctttc accaaagatt gctttcttcc ttaccattta ttccttaatc 7500 agcttcgtta gtatcttttt tacaaccaaa ttaccagttt ggtatgttaa ttcataatgg 7560 catctaaaat gcctgaaggg tctcccccta ctagtcgttc tattcaatct cgaaattcca 7620 gttactctac ctcttccaac gaacgtattg gaacaccctc tacgatttcc ctatctgaaa 7680 attcagatct ttctaaatta caaagtacta atgattttga gtcgcgagaa gatctctctc 7740 ttacttccga tgacaataat gaccccgaat atgttatgtg ctacaacact gtttatcacc 7800 aaaagacaaa aataaatgat aaacttttat ccgaaactga gcagttacgt aaaatttatc 7860 ctttagaatc ccgtgtattt ccaaaaccta ccattgttaa agagattacc aacgagcgaa 7920 ccaagcgcta cactttttat gacgatgatg ctcctcttac taaccaacat actgttttag 7980 atgaagcaac ttataatcga attttaaaaa ggatagactt tttcattgaa aaagtcgttg 8040 aagtcccacc tacttaccat tttttatcgc tattaaacgt tcaattacgt attcaaccaa 8100 tttggtggat ggatgaattt gctgaaagaa atggtattga aagtttactg tctgctttaa 8160 gaaacctggg tcactatcct gaacgtgcat ctaaaacacc tcttgaatcc caaataatac 8220 agtcattatt tcactgtttg aacagcgaaa actgccgtcg tcgttatcag tcttcagcta 8280 aatgctctgt tccaggattt aatgctctag gtactattgc tgagactgtg ctttcaaaaa 8340 gtttaaattc agctcgcatg gctacttttc tccttaaatt cctttgtaat aaaaaggggt 8400 tgagttactt caaagctgta atcagggctt tcgaatggct cgtcgagcaa aagttatcaa 8460 aaactcggtt tagcgcatgg atgcattcct ttaatgatgt gattactggt gtccgagttt 8520 gtgctgattc atctcctcaa gcgattgttc acatggacga atttgaagat acggactgct 8580 tgattgatta ccttgttgca actttagctc tcattcgaga tttatgtgct gctccaccgg 8640 atttgcaact taggtgtgct ctaaggcatg aattgttatc tgctggtctt caaaaggcca 8700 tcgactcttt gttaaaatgg agaaacagac acgtccgtga tgctctgcaa ttactaatca 8760 aagagcataa tgcagatgct cggcgtttcc gaagtggtag tgatgtgaat aatgtagata 8820 ggaaatgcgt aaagaaacag atgaactata gagaagaatc acatacacct catggaaata 8880 ctactcgaaa gacctctact cctgtatcta ataatcgacc cacaactccg gaacaacagg 8940 ctgtttggga tgtttttcaa agaatttata ctcgctttac gggaagtgag gggtctaaag 9000 aaagtttcat taaactactc gagtattttg tgactgaacc cgacaacgga aaaattcaaa 9060 aaagtatgca gttattgact cacacgcttg aggcactgga aggtttcaaa actgccaaag 9120 cagatactaa tgtcggtcta acgatcctat ctcaaagact tttagacaaa cttggtaccg 9180 cagaggagat tgcagagtac aagacaaagt ataatggagc catgcttgaa aacaagcatc 9240 tgaaagaaca agttgaatct atgctttccc aattgaacgt tgggccccgc gaccctatgc 9300 agtttctgaa gaaacaattg gatgaattga aagctgaatt aaatcttaga gacaatctcc 9360 tcgcatccat gcagcgcgaa tttgaaacgc gttatagagc tcaaattcaa gcatacaata 9420 agttgcaatc ccaaatggaa cacgtgcaga attcaaatga gcagcactta caaccgggct 9480 tacttaataa ggtttcaaaa agttttgaca gtgttcatag aagaaacctt tctcaagatt 9540 ctctagatgc gatgaccgaa cagttttctt atcatgttga gccaaatatt ttaagtggaa 9600 gtggaattcc tgttcgtgta catacaccat ccaaaactga agatttggac gaatctttct 9660 ccggaagtga aatatcttcc tcgccttcgc cattgctacc agatgtttcc gacaccgtag 9720 aagagcagca aaagttatta cttaaatctc ctcccccacc acctcctgct gtaatagttc 9780 caacaccagc tccagctcct attccagttc ctcctccagc tcctattatg ggtggacctc 9840 caccacctcc tcctccacct ggtgtagcag gagccggacc tccacctcca ccacctccac 9900 cccctgctgt ttctgctggt ggaagccgat attatgctcc agcaccgcag gcggagccag 9960 agcctaagat tgacgaaacc agcttaacag aagaacaaaa gattcaactt gaagaggcca 10020 gaaaacagcg taaagctgct gatgatgcag cgagagcagc catagaaaag tatacaagta 10080 tccctagtct tcgtgatctt cacaagccaa ctcgtccttt gaagcgcgtc cattggcaac 10140 gggttgatcc actgcctgga ccaaatgttt tcacaaagtt ctgcttaaat tttgacatta 10200 ccgctaaagt ttttatagat aatgggcttc tcgatttttt ggatgagaaa tttgataaca 10260 ctcctaggga agattttgtt gcagtggaaa tttctgacca acgatcttct cttttacctg 10320 atacagttga acaaaatatg gctattattt tgcggtctgt atctaatatg ccagtggagg 10380 acttagttca aaagttttta gtcgaacccg actttttacc ggcctcaatt ttatactttg 10440 accgcgctag ccttgcatct accaatgcct ataccgatcc attcattcct tatagtacgg 10500 attacacaaa gaaaaatcca aaagaaccaa cggcggatgt gaacagttta tcttattttg 10560 agaaattttt tgtattgttc gtcgttaacc ttcggcacta tttccaagaa aggatgaaag 10620 ctctaaaatt tcgctcgacg ttgtttggtg atttggaaat acttgaagtt cgtatgaaag 10680 aagtcattga cacttcggac agtattatgg aggataaaaa ttttgctgaa ttctttcaag 10740 tcttactgat tattggcaac tattttaatg aaccttatga tcgagcatct gcattttcct 10800 tgtatatgat atatcgcctt gaaactttac gagatagttc ctcagctcta actttgatgc 10860 actactttga tgagattata cgaactcgtt tccctgaatt attgcaggcg gaatccacgt 10920 ttaaaaaaat tcagagtgtt tccggataca atatagatgc tatggttgcg ggtgtagatg 10980 gtgcttatga tgaattctgc gactttcaaa cgtctctcaa agacggtgct ctatcgaaat 11040 gcgaccagca tcatccagat gataaggcgt acgatattct ttccgaatgg ttgcctgagg 11100 ctaaagaaag gattaggaat attaaaaagc ttaaaactga tatgctcact aaacttgaaa 11160 acactgtgaa gtatctttgt gaatatgact ccattgataa ggttagaaac tctttcttca 11220 aaaacctgaa ttctttttat gaaatgtatt ccatcgccaa agcagagaat gaggaacgtt 11280 ttgagaagga gaaaagacga atcatgtcgg aggatcgtga caaactgatt cgtggtcgcc 11340 aaaagacatc cattgtagca aaatacagaa ataaaagaga gttaccagaa gactctgatg 11400 ataaacaaga tacggcctcc aaggataaaa attccttaga aacaattgat gaaaaaatgg 11460 aagatgccag taaaatagaa ggtgatgcta agaccggaga tgataacgaa atggaagatc 11520 ttgataaaat ggaagacctt gaaaaaccag attatgctga agaaaaagat ccatatataa 11580 ctgtaatgtc agaattacga tctcgtatac aaaatgtccc taaaaggact gttactgttt 11640 attccgatga aggcgttgct acacttgagc ccggagctca aggggatgat gttgtagata 11700 aggccaaaat gattcttgaa aaaatggaag gacattccca actattaact tcttcggcaa 11760 atcctgatga ggaggtttta cgtgccaaac tgaaagctgc tgagcgtttg caaaaacctg 11820 caattcctag aacacgccgt aaaggccaca ctgaaccaaa gagtgctaag tcactacttg 11880 cagaactaac taacgggtct aatgcttcaa atctagttga aaatgaccgc caaaaacaat 11940 agttgctcca ttgttctttc taggatggat ttttagaaca gtatatctgt acattacata 12000 cattgacgat ttgtctgaaa gaagttaaaa atttgtgtgc ctgtattttt tgaagctgct 12060 tcaaaatata ttggtgacac agttatctgt attattacgc ataccgcttg tcgttaaaaa 12120 ggctaaattt ccaaaaaact gacagcaaat acaatcactt gtttttccaa gtgcttagaa 12180 gtactgaact tacgttgcaa aacgttgttc atttttgact atcctttttt gctaaatgtc 12240 agcattttta tttgaaaaga gacatgttgg gataacgatt cattaagggg agctttttat 12300 tacttaactt catttttatg aagctaacag agaacaaatt tggataagcg tcgcaccaat 12360 tgtaaaagga atgcccaatc gctttattta gatcgactaa aatgttgatg tttgtttgaa 12420 atctccacca aaaattttat tctattgtca tctttattta ttaatctttt ttaatcattc 12480 gtttaaacag tccttgttgt ttaattattt attgctccta ttttcaactg ttgacctagc 12540 ttttgaaata taggatgaag cgttagtttc ctgtataaaa cttgaaataa atgcaattat 12600 gttttaaatt ttgtaagtat ctagtttacg acattgtaaa ttagaaaatc ttgtttgttt 12660 tctatgtgct gtcaattcgt ttccttaatt ttttcccttc ttatataaac gaccgagtca 12720 agaagcaatt tgtatttaca acattaaact gaaagcctgt aaacaacttt tttaattcat 12780 acaattcata ccaaattgga gtacaaacct gtgacctctc atccaagtaa catacatatt 12840 agaaggaaag gaatgcaata catagagcta actagtgcca gcaagaagag gcatttgcga 12900 tgtttcagta tgaggcttta catgtaggct gtaatcgtat accaactgca gcaacatggt 12960 cttctaatct tggccttatt tatggagctg aaagattaat agcagttgct gatccagtaa 13020 gtattttttg ttgtaaaact aagtgttatt tgcttatggg ttaatcctcc aaatcacgaa 13080 ttaaccaata attagttcaa agaaatcaat tacttgatgg cggggcatag tggaagaatc 13140 aattgcgttt gtgagctagc tactaatagc gaatatagaa gcccttttat actctctggt 13200 gcttcggata agactcttcg gctatggcaa ttggaagaag agtatttcac gtgtattaag 13260 accattgagc ttgaagcaac cgtaaactgc ttgtgtgtaa acgaaaattt agtagtttgc 13320 ggctgctcga acagctcttg tattgtgtat agctggaatg cagagcagag aaatttaaca 13380 gaaattagta gatttacttg ttctgagatt ataccccttg aattcgctat tgtgaaacta 13440 gaccacggta tcattcttac ggtttgtggt tctagtaaga agataatggt gtatggctcg 13500 gattcagcta ttagtagctt caagctgaaa gccgttttac gtggtcatct tgactgggtc 13560 cgaacgcttt cctttaaaaa aacatctggt tcaacggcga cacttgcatc tggaagtcaa 13620 gatcgttata tacgtttatg gaatatttca ctttggggaa gtgaggacga aaaggtttca 13680 gaagaattct ttgaatctgt tttgtctaat aaaccagtcc gttttacgtt aggtaaaata 13740 gatctaaaga ttgtatttga tgctctatta atgggtcatg aggattgggt gatgagtgtt 13800 gattggcacc ccacgaagga aatgattttg tcctcgtccg ctgactcatc aatgattgtt 13860 tgggagcctg atactaatac tgggatttgg gtggtgactg gtaggatggg tgagatggct 13920 tcttctcacg gatctactac agcaactggt agtgctggag ggttttgggg aggtttgtgg 13980 aacccaaatg gtaattgtgt agtatgctgg ggaagaactg gtggatggag actctggaag 14040 caagatgctg ggcaatggct ccaacttcca tctatttctg gtcacacaaa gtcagtgaaa 14100 ggcgttgctt gggatcctga aggtaaattc tatttatccg ccggcacaga tcaaactact 14160 agattgtttg cacgttttaa aaaggataat gcttggcatg aaatggctcg acctcagatc 14220 catggctatg acttaacctc tatatcctgt atgccttctc gaattggatt tttgagctgt 14280 gccgatgaaa aggtgtctcg tgtttttaaa ttccctaaaa caattgttag acttctttac 14340 cgtttatgcg ataccaatat tggggaggaa agcttacctg atgctgcaaa tgttccttta 14400 ctaggtcttt ctaataaagc taccactgca tctgaaactg gtacggtaaa tgcagaagaa 14460 gttcagactc ctgttgctga tgtgattggt tctttgaacc atcctccttt tgaagaacac 14520 ttacagcgtt tgctattgtt tccggaagtt gaaaaattat tcggccatgg ttatgaggtt 14580 tatgcatgcg ccatatctaa taatggtaat attgccgcga cttcttgtaa atcacaaacc 14640 cccgaacatg ctgtcattcg gttatacgaa acgcagtcat ggaatcagca gcaagtcctt 14700 aaaggtcatt ctttgacggt tacaactata aagttttcac ctgatgaccg atacatttta 14760 agtgctgggc gggatcggtt ggtgtgtttg catgagcaag ccgaaaattt attggattat 14820 aataactttg cttctataaa agcgcattct cgtattattt gggatgctag ttgggctccc 14880 aaagaaatgg gttacttttt tgcgactgct tcgcgtgata aattcgtgag taatttttta 14940 tttgatcaaa tcttgctaac tatttaggtt aaattttgga aaatcaatga caataaaaaa 15000 atatgtgatg ttgctgctct ccaattttct gatgctgtta ccgctgttga ctttgctccg 15060 ttctttcaca acgatgaact cttgcttgcg gtaggaactg aagctggtaa aatatttatt 15120 tggagatgcc cgagagagaa tcttaccaaa tggtacccaa cacgtttacc agaccacatg 15180 gctcctatgg agtcaattaa ccaaatttta tggaagccca cttttgaaac tatggggttg 15240 tattctcttt taattgctgg cgaagatacc agtgtacgac ttttgaacgt tacgttggga 15300 taaacttgaa aataagtaca attggtaatg ttagattggg ttggcctgtt ttaaacatac 15360 ctgaggggtg gttaaaaatg cttagataaa ttatttattg ttataattgt cgataaataa 15420 aaggaaggtt aatgggttgt taggttggca taattagtgc tgaatggtag acattcatca 15480 gattgattca ttactttagt tgttatatat atatataaat atgtattttt aattattagt 15540 atcaaaaact ttggtgtagt agtcttctca attaactcaa acacaatttt acatgttaga 15600 gaaaaaaaca acacataaaa atttttttta aaaataaatt atatttaaaa ggtagataag 15660 gcaagatttt aactaagaag tattttcaag cgtaatagaa tgcaagttgt aaatctaact 15720 aagaacattg attacttcta cgaaatttag tttatttttt ttccctttct attactcgtt 15780 tacatttatt gaaagaacgg agcaagctag gaagtaattt atattcaact gaatgactgc 15840 attttcggta gtgtccaaaa gtaacactta ccaactccaa acatctattt tgcaaaccta 15900 agtcttaata aagatacttt ttattaaagg ctatattttc tcaggtttga atttgttgac 15960 tcaacgagtt aatacttata tactccggcc ttgctaaatc gatattctgt aaagtttgac 16020 agtgttgtat ttgcctacag gcttaacgag taattactta ttatttattc aaaaaaggga 16080 gaaaaggtac taagtacaac ttttgagttt tagaattgga gttttgggag agcatttgct 16140 gtttatttat cttatacgct cctttaattt ttggcacccc ggaggaacat gagccaagat 16200 caagaagaag actactccaa acttcctcta gaatcaagaa tagtacataa agtatggaaa 16260 gtgcgtctat ctgcttatga agagtgcagc aaatcgtttt cactttcagc agatggttcg 16320 gataattgct ttgagctttg gaataatcag agtgaattgt ggaaatcagt gctgactgat 16380 agcaacgtag cagctcaaga agctggtacc gcagcgtttg tagcttattg caggttttcc 16440 gatccttctc atttacttaa agctcgtgaa atatcagtcc tttcaatttc agagaaatgc 16500 ttaacatcac ctcgcgcagg tacaagggaa aatgcactag aagctcttat gctattagtt 16560 gaagcagatt cagctgcgcc agttatagaa tcaatcattc cttctttatc ggctcgatcc 16620 ccgaaggtaa tagcttctaa tgtcgctgcc attgctagtc tagttgagca gtttggtgct 16680 aaagttattc cttcaaaaat gattattcca catatctcca acttgtttgg tcatgctgat 16740 aaaaatgttc gtaaggaagc atctcgttta actgtaaaca tttatcggtg gacaggggat 16800 cctttaaaag atttactatt taaagatcta agaccagttc agacgaaaga gcttgagtct 16860 ctttttgctg agctaccaac agagcctccc aaacaaactc gttttttgaa aagtcagcaa 16920 cctacatcag agccgaatgt tgaaacacag gtagaagagc aacctgctct cgagaatgaa 16980 gaaagtgaac cagaaccgtc agatgatcaa tttgatttgg tagaagaagt ggacgtttta 17040 cccaatgtgg atcctaacct ggaaacttta atggcttctt cgaaatggaa ggatcgtaag 17100 gaagcgttag acaaactact tcctgtctta tctcaaccaa agatcaaaga caacgatttt 17160 tttaatttag ttgctattct cacaaagtct gtttcaaaag acgcaaatat catggtggtt 17220 ataaatgctg cacactgtat acaagcgatg gctaaaggtt tacgctcaaa tttttcgaag 17280 tatgcctcaa catctattaa tgcactgttg gaacgatcca aagagaaaaa ggctaatgta 17340 atcgaatcac tatcttctgc gatggatgct gttttggcta catccagttt ggatgactta 17400 gccgagctca ttgctagctt tgccgggaac aaaaatcctc aaatcaaaag ctcctgcttt 17460 agtttgttct cgagatcttt cagtaatatg acatccttac catctaagtt tacagttgat 17520 acctgtgcta aagcatgcgt tcctggtgtt tctgatacct ttgagccggt gcgtagtgcg 17580 gcagcagaag ccttgggtgt tttgatgaaa ctcgttggtg aaagagccat taatcagtat 17640 ttaagtccgt tggacgacat caggaaatct aaaattcgtt ctttttatga aacagctaca 17700 gtaaaggcta aggcacctac aaaaaagtcg aaagttaaac cttcaaaaca agaagaatca 17760 aaagtcgtcg taccttcaaa tgctaaggct gtcaagaaat ccgttgttcc ttctagtcca 17820 gttgtaccat ctccacgaaa ggcaactaac aaatcgcttt ccatggatgt atcaaagggt 17880 aatgcatttg agaatggtcc tttgttacca agaccgacta cgaggccagt ttctcgaggg 17940 ctttcacgag gcacatcttc cagtttgcaa caaaaagtaa aagcttccac tcctttgaat 18000 tcgggagcac ttaacgaaac ggtgcaaaat ttgaagaaca tggagttgga cgatccggct 18060 cctcaaccgg ctaagcattc acgagttgat cgttatgaac accctaaagt attagaagac 18120 aatgactcta ccatttcgtc tttagaatct ctgaagagag aaaacgagga gttacgagag 18180 cagttgaaag ttgaacatga agagaatatt tctatgcaaa aacaactcag tgaattgaaa 18240 ggtgaattaa ataccttacg cagtgccagg aaagcctcac caataggaga cagaaaacct 18300 gcatttatgc gaagagctaa tactgacttt ttagagctct ctacgagtcc ctcatttcaa 18360 cgttcagtga gggaatttga acctactaga cctaaacttt atagctctat agatgtgaat 18420 cagagatccc ctttagcatc tgcgaaaaca aatggtaatt tcacgtttca tgctgaatta 18480 ccaagatcac cgttttcgtc aagggccaat aatatcaatc ctgattggac taaagccatt 18540 gatttagctg ccaaactaaa acaaaaaatt actgagatga aacaaacaga ccaaagacat 18600 cagggattga ttcactagtt tttaaattct ttcgtttaca ttccaatgtc ccttacttcc 18660 ctttctattt tttaatgttt tagaataatg ataatatcgg tttacaaaaa taataacaaa 18720 atacgtattc tcgtttatac caaatttctt aaaatcagat ttaactatag gttaaagatg 18780 gagtcaaatg gtaactcaaa cacacaacac aaacaaacat ataaaataaa taaaagaatt 18840 ttaacgtacg aatttatcgc attaaacgta ttagtgtcat taaaaaaagt agtctgttta 18900 attttgcatc acaagtatac tgtatagccg taccaagtat aaacgaaaac ctctttttaa 18960 aaaaattaaa cataataaag aaattgttag aagaaaaaaa ataaagatat gcgtaaagta 19020 cagacagtcg aaaaaagagt aacaatcaca tgagtctttg cccaatgaaa agttctaagc 19080 tttgttcaaa aagtccggag gactgatgtt gctaaagtag tccaaagaag cggtggaagg 19140 agtatcggca tcaccatcat cgtcctccag gtagaaataa gaatcacgat aaggggaata 19200 aggcggtaaa tgggacaatt ccgactctaa tttcctatga aacagatata taggaagctt 19260 aaaatccaag gaatctagcc actcatttag ttttttcgca ttttttcgag agtatttaga 19320 taaatttggt agggaggctt cggaaggaga ggctaaagat tgctttacgc tgttttcagt 19380 atcgccatgc cagcttccag aaagcgaaga agatgatgat gagggtcttt tcatagaaaa 19440 tagtgaatta gatttagctt tgtgagtccg aaggaatggg ggagcgagtt ttcgggataa 19500 agaggagggt tcacgagagt gaattgatac ataaattgaa tgtcgcacaa ggaggtgtgg 19560 attttctgta cagcttccgt gaattaagtc gttcacagga attgtgaact caactcttga 19620 atggaggcca ggaacaatag gtggagacca cttaccatcc tcaaaaagga cagtaatgga 19680 gtttcgaaaa gcatcattaa aaagaaaaaa ggtaatgctt tggacaagaa gcactcgtat 19740 ataatagcgt tttaacttct tttcgactac aggagacgag gtacgagata atgaagagcg 19800 tcctttcata tcacaatcat tactcaaacg tggtaaccga tcttgaaaga taaattgaga 19860 atcttgggag ttaatagcaa tgggatctat atggggatca tctgttccag cagaacctgg 19920 ggtagatgac agtacatctg catcttcgga ctccaaatca attaaaagtg ggcaaacaca 19980 gcctggtcct ttatagcact gttgaggata tttaaagaac gcagttagaa atgaatactt 20040 tgaagacttc attgatagcg aagtaaaaca cgcatcgttt aggggcgctc cataacgtat 20100 gtgctgagat tcaggaattc gatcgggatt gagagtaaaa ggtacaacta caggaacatt 20160 ggctgacttt ggcatacgac aatcatcttc agtatacaat ttaaccgtta atttgtaaga 20220 aatcgaacct tcttgagtca caatcgttcg tggggtgcac ctaggaagtg gagcaatgat 20280 atcaaacgta tagaaaactc cttcctttac tttgaaatta tttccaagat cccagtcgat 20340 atgattgaaa tgacactcca gcggtaactg tctctcagta ggaaactttt tcagaccagt 20400 aaagcttgca gtaaggtatt tacaataaaa tgtatcagtt gtcacaaagt acaccttgta 20460 tttaaggata gaacaaggat gctgaacttc ttgaaaggtg tcagaaaccg ctcctaaaat 20520 atgtattttg tctctcgaat tgtccatgta aattaagggc agagacaatc aagggcacca 20580 aaaaagagac atttcaacgt caagcttaac cttacaatcc tttaacaaag aattgaaaag 20640 aatacttggc aatttatagt tttcgtaaat taaatggagg agatgttgta cgagatatgt 20700 catttaaatg agagggtcat aacaatgaaa taacgaagct tcagtataat tagttctatc 20760 gttatcattc accatatgag cggcgttagc tatcattata caatgagtgc tctttagtaa 20820 cgttgggcat gagactgata ctcacaatat gacatgcaag ttaatccttt attccaaaat 20880 aaaacttaat aaaaagcatg aagcccaaat gaactctcat tcttccatta ggtcgataaa 20940 agttattatt atatttataa tggtatactc tatagcccta gtcatactaa ggatagcaaa 21000 gtaatattac ctccattata ttatacatta caaagaaatg ccgacacagt ttttcgtatc 21060 cttacagaga gtgcaaaaga catactaatt actgttgcta agctccatat ttctgatact 21120 gaggcacaac gaagttttca cttaacttta atgaaattta tcatctcgta aaatggaatg 21180 taaatacagg tgaacgggta aggaagtatt agcttttcag ttgtttgagt aaaaaaataa 21240 ttttcaaata catgaattat gttggtaaat aaacaatctt attcagcacc tcctaaagca 21300 agtagacgcg gagttaaatg atcccttttt tatgttaaat gtcagtaagg caataaaata 21360 ttaaaagaaa atttatcgtg tccgtcctgt attgagttga aaaattaaga tcataaactg 21420 ttccaaaata ataatctttt tttaggtata acctgcctca tttgaacaat aaaagtgatt 21480 tgtaccattt atgctctttc aaggaaatag agaaggggag ctaaacaccg ttgcctgcaa 21540 tcagagtacg aatacattga tgtatttcac tttcgtagtt taaccccgac gaagattcca 21600 atcgctcatg taatgaggca tcaagacatc tttttagcat ttttaataaa ataacgactt 21660 taggccacgc tttaatgcaa tatgcttgat caagtattaa tcccttacca agaggatcaa 21720 tgagtatatc atttgctccc agcaaaatca ttccatatgt attgataggt gtacaatttc 21780 taaggaaagg tttcgtggtt tctacctttt gctcatatgc cacgaacgta catcttgaag 21840 catttggaga attaacaaac atagtacttg aaggatgtat gaataacctt tggttgtttt 21900 gatcataaaa cttcgtcagg cgagcttcct gctccatttc aagcgatcca gaaaatgaag 21960 caacaaattt tttatcagga taaacacatt tcacaacatt gggacttaaa gcagcagcaa 22020 ttagagtcga tagaacagtc aggttttcag ttgaatacca atcaaagtta ccagtcagct 22080 ttttagtagt tagttcaagt agctgtgcag cttcgctcaa ttcgtttcga ttctgtcgaa 22140 tttgttgtaa cgttgtgtaa tgaagatgca tctcttcaca ccactgaact gttttcttta 22200 cacccctggt ttctagtatt tcgagccagt tgtgatatac tcgagcatca gccaaaacat 22260 ctccccatcc ttgactttgt ttactcctta tttccctagc ttcatcgtct cctaagaaag 22320 gagactttgt agagagaata gctgtaatag taagcgcagg ttccaaatat ccaaagatcg 22380 aaccaaacac caaaagcttt ccaagcttta gatctatggg taatgacacc taaaattata 22440 ttagtttcac ataaaaacac atcattactt actaagtatt ctcctaaacc agttaaatct 22500 tctgacacgg tgagagcacc gacttgaatt agttttttca aagcaaggtc taccgttgca 22560 tcattcggtg gatcaataag gctgttcata aattttttga ttgaaccctg gttcacagaa 22620 ttaccagcag aagaaaatct cttgaccaaa ggaactacgt taagacaaac ctgacttaaa 22680 gccgtccgta aaacttcggg aggtgtttgg cctagcattc ctttttcttc aaatcctctt 22740 gtatataact tataacatat tcctttctta acacgacccg cccgaccccg gcgttgttga 22800 caagcagctc ttgaggccca agtctcttta aaagtcacca gatctcgttc aacatcataa 22860 tcaatttgct taactctgcc gctgtcaata acggcaacaa catcatcaat agtaattgaa 22920 gtctccgcaa tatttgttgc acatatgatc ttccgctttg tgtatgtttt gaaacatctc 22980 ctttgctccg aagtattcaa agaggcatgt aatgggagga cctcaaattt tgagccgtct 23040 tttgatttta tttcacgaat acaacgagct atgtttgaga caccgggaag gaaaaccaat 23100 atagaaccac tagaggaacc aagttcagca tcaatagaac taacaagtct agaaataaga 23160 tgataatcaa tttcatattc ttttttcttt cttctgggaa cgtcttcctc gtcatcatct 23220 tcatttagct taggcgcaaa atcctcaatg tagtaatcct tgatcggaaa agtacggccg 23280 tgaatatgta aatgaccagc atttccaaaa taatatttga atgtatcgga gttcaccgtg 23340 gcactcatca aaatgacttt caaatttggg atacgagaaa ttactagttt caaaagtgtt 23400 aagagtatat cattttcgat ggatctttca tgtacttcat ctacaacaac acaagataaa 23460 gtactcaaaa agcctagacc atgttgctga attcttctaa gaagcaaacc tgtagtgcaa 23520 aactcaagaa gggtttcttt agatatggat ttttcaccat gtacactgta accaacttct 23580 tttccaacag ttgtatcacg ttcgaaggca actctttccg ccaaacttat cgcagatatt 23640 ctccttggct gtgtacaaac aactgtttgc aaatcttttt ctccagaaga aagataatgg 23700 tccaagataa attgaactac ttgtgttgat tttccactac cagtttcacc acttataaca 23760 acaacttgag aatgctgtat ggcgtccata atttttctcc ttgattccca tgcagggagt 23820 ttctcacgtt cacgaacttt taattgatat gaaggacttt taaccctctc actccagtta 23880 ttacataatt tttcagataa ttcgcgcgaa cggcgaaata attttggctt gaaactgtta 23940 ttctttttgg cagtcggcgc agacttgttt tgagaggata aagagacacc aattgttgca 24000 gctgaaatat ttagtaagct tccaatattt tgtaaaaagt cttcaatatt ttcctgaaga 24060 tgattataca accaggataa catgcattca cctctaagat ccattgcgta aacaaccatc 24120 tttttaagaa tactcaactt aatataggat gccattcttt ttgtagagga tagagacatt 24180 aaaggaatgt gtgcaggata cgaacgggca ggccttctaa aatcgacgaa aagctcacca 24240 aattcactag tcgggtagtc aatacgcact ctacatccat tctctatttt tgagacctta 24300 ttatccaaaa tagattgcaa agcactaaca tcatcatccc attcggtact atttggttcc 24360 aaagatatat tcccatcaaa gctttcacca attagatgct gctgtaagta ctctgaacta 24420 atttgaatgt tattttcaaa agtttgaaga gtagaaaaac ataagtcaaa gctatagccc 24480 gtctccgaaa tccctgttaa tagttagtgt tgaacaaatg tcatacgcac atacgtttag 24540 cgttgtagtg aatggccaga ttcgctgaat ttagattctg aacagatatt cctgttgtat 24600 aatcagaagg aagaaatctt gtaggaagat cgtcttctgg aacatgaatg attagccact 24660 ctaaagcatc ttcaagggaa acacagtact gacaagcttc tttagcatga atgtctcgaa 24720 aacctaaaga aattaaatca ttaacaatag aagtatcggg ctctaaattt tttgtatcct 24780 ctagtatatc ccacgtgttc atattgcgaa aaaggttctc tagagagcga cgattttcaa 24840 gactcatgtg aataggaaga gcatatttga aattgaactt tgagaagtgt gaaaggcttg 24900 tgtttttgat agatgtcaaa gagacctttt catttttctg agatgctttt ggcggtggtt 24960 tggcagctga agaagcgcgt gctgcctgta gttctttggc tgctttgaag ggatcttcat 25020 tgtaaagcca gctgtgctta ttttttagct cttccttctt ttgtttctcc atatcaaacc 25080 atatattccg atgttcaggt ggaagggcat gttgtaatga tttatgagac attatctgtt 25140 agaaattaaa gttggttaat gattgcttga aaataaataa gtatagatcc ttactcgatg 25200 caaagcataa acggcgccaa catttcgtgc ttccactaac gtttcttttt caggaaagta 25260 gccattctca taataggact tgggaggaat cagagataca tggtctaata tcgaagggtt 25320 ttttgggtcc ttcttagcaa gtacgacaga agtaaaaatg taatttttag atttggtttg 25380 cctctgttta gaagatttta gtaagtatgt gttcgataga ttggttaatt cgcatctttt 25440 aagagctgac ttaccacctt aacatcactt ttctcccatt tacttctttg gcaatgttca 25500 tttagtaaaa cgacaggaat ttttccagtc caagagcttc ctcctactaa ctgtttggca 25560 gtaggacgtg aagtcgtttg caggcctgct gtttcctgtt tatttttttc aattggatca 25620 agtgagtttt tctttttccc tttgatattt ttttccttgt tttttgaagt ttctaaatta 25680 acctccgatg attttccctt ttttcctttt gaacccattc gatggtaata tggttgaacg 25740 caaagaattt ttaagccagt gtgctgagtt gatgaataat tgagaaaact aatttatcca 25800 agaaggtaat tcttattcta agtcaaagtt aattccatca aatttttggt aaaataaata 25860 catcacacat gaaagaagaa ggtatattgc gttattgaaa atcagaaagt tgggtgtttg 25920 aatttaatta ttgtgaagcg ttgaaagcgt ttattgatta tatttctttt aggatgtttt 25980 tgctattgat ttaaacatcc cccgtacgtg tactacagct gtcaacattg gtaataagta 26040 cgcagttgga catacgcgta taagagcatt tagaaatttt tttgatcagg attacctttt 26100 tcttttgcaa ttttaacaaa tcatggcgca aacaggaata gtaagaagca ttctcaacgt 26160 cacttttgag aatatggaat tcaattcgca aagtttcaag acaaaatacc ggttatataa 26220 atccacagcg tttaaagaat gatcgatcat tgagacgtat gagtgtttca gatgatgatg 26280 agtttcctgt cttcgagcaa atccttaaag agaccttact ttttctggct cacttataaa 26340 cagacttaca tcttcgtttg aattgaataa tattcattag cactagcaaa ggttcataat 26400 ttatggagca atgttgacct ggggattttg acaattcgct aaattctcca cag 26453 //