ID SPCC757 standard; DNA; FUN; 37228 BP. XX AC AL031825; XX SV AL031825.1 XX DT 05-OCT-1998 (Rel. 57, Created) DT 13-FEB-2002 (Rel. 70, Last updated, Version 3) XX DE S.pombe chromosome III cosmid c757. XX KW 3'-end processing of multiple small RNA species; KW acetylornithine deacetylase; alpha-amylase; catalase; cta1; KW gene-free region; high-affinity nickel transport; LTR; membrane transport; KW pre mrna splicing factor; rna binding protein; transcriptional activator; KW tRNA His; yeast exosome 3'-5' exoribonuclease complex component; KW yeast Vacuolar H(+)-ATPase (V-ATPase) assembly protein. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-37228 RA Lyne M., Rajandream M.A., Barrell B.G., Bothe G., Pohl T; RT ; RL Submitted (02-OCT-1998) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and GATC GmbH, Fritz-Arnold-Str 23, D-78467 Konstanz, RL Germany XX DR GOA; O74869; O74869. DR GOA; O74901; O74901. DR GOA; O74915; O74915. DR GOA; O74916; O74916. DR GOA; O74918; O74918. DR GOA; O74919; O74919. DR GOA; O74922; O74922. DR GOA; O74923; O74923. DR GOA; P55306; P55306. DR SPTREMBL; O74901; O74901. DR SPTREMBL; O74913; O74913. DR SPTREMBL; O74914; O74914. DR SPTREMBL; O74915; O74915. DR SPTREMBL; O74916; O74916. DR SPTREMBL; O74917; O74917. DR SPTREMBL; O74919; O74919. DR SPTREMBL; O74920; O74920. DR SPTREMBL; O74921; O74921. DR SPTREMBL; O74922; O74922. DR SPTREMBL; O74923; O74923. DR SWISS-PROT; O74869; NIC1_SCHPO. DR SWISS-PROT; O74918; RR45_SCHPO. DR SWISS-PROT; P55306; CATA_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c757 is overlapped at its 5' end by cosmid SPCC1884, CC EM:AL031787 and at its 3' cosmid SPCC613, EM:AL031644. XX FH Key Location/Qualifiers FH FT source 1..37228 FT /chromosome="III" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c757" FT /map="IIL" FT misc_feature complement(1..500) FT /note="nominal overlap with cosmid SPCC1884, EM:AL031787 S. FT pombe chromosome 3" FT CDS 1..974 FT /codon_start=3 FT /db_xref="GOA:O74869" FT /db_xref="SWISS-PROT:O74869" FT /note="SPCC757.01, SIMILARITY:Salmonella typhi., O68290, FT hypothetical 31.8 kD protein., (294 aa), fasta scores: opt: FT 644, E():0, (41.3% identity in 264 aa)" FT /partial FT /gene="SPCC757.01" FT /gene="SPCC1884.02" FT /gene="nic1" FT /product="NiCoT heavy metal ion transporter; no apparent S. FT cerevisiae ortholog" FT /protein_id="CAA21226.1" FT /translation="ITAIDNLTRRLLSTDKPMSTVGTWFSIGHSTVVLITCIVVAATSS FT KFADRWNNFQTIGGIIGTSVSMGLLLLLAIGNTVLLVRLSYWLWMYRKSGVTKDEGVTG FT FLARKMQRLFRLVDSPWKIYVLGFVFGLGFDTSTEVSLLGIATLQALKGTSIWAILLFP FT IVFLVGMCLVDTTDGALMYYAYSYSSGETNPYFSRLYYSIILTFVSVIAAFTIGIIQML FT MLIISVHPMESTFWNGLNRLSDNYEIVGGCICGAFVLAGLFGISMHNYFKKKFTPPVQV FT GNDREDEVLEKNKELENVSKNSISVQISESEKVSYDTVDSKV" FT CDS complement(1598..2815) FT /db_xref="SPTREMBL:O74913" FT /note="SPCC757.02c, len:405, SIMILARITY:Arabidopsis FT thaliana, CAB45057, hypothetical 44.2 kD protein., (388 FT aa), fasta scores: opt: 435, E():1.1e-22, (27.8% identity FT in 400 aa)" FT /gene="SPCC757.02c" FT /product="hypothetical protein; conserved in A. thaliana; FT Pfam-B_37808 domain; no apparent S. cerevisiae ortholog" FT /protein_id="CAA21227.1" FT /translation="MAEEGYVAIVTGATGLNGAAIIKRLSEDDNCKTIHCISRSLKDEY FT PRKIKHHSIDLLNEEPKDIAKKFSLEGVKGINYAYFAAYKEENNEEKLCEVNGNMLRNF FT VQALELTSIQTLRRVILTTGLKFYGLHLGEVRLPMIETDIRVPETFSGTPNFYYVQEDI FT LKEFSNGKKWDYTIAMPNDICGVSKGSYMNEAFTIALYALVCRELHEPFRFPGNEKFYL FT GFDDISYSKLIADFQLWMTFKAECSEEKFNIVNGDIHSWSRTWPKIAEYFGVEVPKNQF FT ATDFTLSTEVTLSTPSPINLYEKELGIKHTPNSKIINQISLQQWVKQKKVQDAWRTIAE FT REKLNAHALEVGTWAFCDFLFGRTYNVISSMSKARKLGYTDYYDTFDGFKETFDELKKQ FT KQIPQN" FT CDS complement(3644..4378) FT /db_xref="SPTREMBL:O74914" FT /note="SPCC757.03c, len:244, SIMILARITY:Schizosaccharomyces FT pombe, YA02_SCHPO, hypothetical 26.1 kD protein c5h10.02c, FT (240 aa), fasta scores: opt: 986, E():0, (60.7% identity i FT n 234 aa)" FT /gene="SPCC757.03c" FT /product="putative ThiJ/PfpI family protein" FT /protein_id="CAA21228.1" FT /translation="MASEGKVLLVASSYYGPFYPDGMNTGVHFAELLIPYQVFREAGYE FT VQLTSETGKCKFDDHSIKKSALGEVERDAFDNKDNEFWYALKDIKPADKINYKEFCIMF FT IAGGHAAMFDLPHATNLQTLAQQIYASNGVLAAVCHGPVMLPFVDDTKSPEGRSVVYGK FT KVTAFNSTGELVMGVSSALRERNMQDLNSLFREAGAEFVDPPTPMSDFTQVDGRIVTGV FT NPMSAKSTAEAAIKVSQSLRKT" FT LTR 5109..5453 FT /note="tf2-type LTR" FT CDS join(6261..6455,6581..8440) FT /db_xref="GOA:O74915" FT /db_xref="SPTREMBL:O74915" FT /note="SPCC757.04, len:684, SIMILARITY:Schizosaccharomyces FT pombe, E1319426, putative transcriptional activator, (555 a FT a), fasta scores: opt: 1561, E():0, (42.9% identity in 567 FT aa)" FT /gene="SPCC757.04" FT /product="putative transcriptional regulator; zinc finger FT protein; fungal Zn(2)-Cys(6) binuclear cluster domain" FT /protein_id="CAA21229.1" FT /translation="MSHMDSERLLFKRYLQRLFITRILTLIRLDLSLFRRYNTNTIVGS FT VAYETLVDTVCDVSSNSTFVVKCNRQYPCTRCLKYGEACTYDERDNRKKRHSLSYLHSL FT ESQLARLESFIMTLKNSDPEGRDEMLKSVVFSDHLTEPNDQEVKSEGPIEYPVFLNVQD FT SKTVSFYGPTSAYDLSLPDITKDNKTTWNFQASYSPMVSECLKLFFRYQYSQFLFVYRE FT SFLSDYYYNFHDGFYCTEHLIYAICAIGASMSDDENISRHSKSYYDASWQKLLEFGLDR FT SHLTSVQCLLCLGYYDIGMGNTSLGWLLSGLAFRMGQDLGFQLNPENWYIDNSPAISSA FT DSDIRRRVFWGSYVADKFIGFIMGRPTMLKRSDASIPGSNQLPEFAGLEEFKLNVTDYM FT SLTDFSVCDAVALFVDLSDIADSILLNMFSPTSKNRATNINCVLSNLGKYNLELMNWHY FT KLPDTISWRTIDLKKDRIPNLCAVSLYYHLIRICLNRPFLSRKEVTANDLTPKTICTDS FT INEIVTVIRAHRTANGLRYSTLYIVYAAIVSCSVILLLRDMCTDSELLTLNNDMMFFIE FT VLKECSQTWKLAQRSIVLIENTLKGKTNSQSTSEFVSPISDTENGSSSQQVSEAKDIVE FT PSDVLDELQKFDLLPENDDNFQTFQAFYGGPPIILSPNLYEKKLNEKTL" FT misc_feature 6456..6461 FT /note="gtaagt, splice donor sequence" FT misc_feature 6561..6580 FT /note="ctaatttaatcaatcgacag, splice branch and acceptor" FT misc_feature 6575..6664 FT /note="Match to PF00172 Zn_clus, fungal Zn(2)-Cys(6) FT binuclear cluster domain Score 37.73" FT CDS complement(8813..10015) FT /db_xref="GOA:O74916" FT /db_xref="SPTREMBL:O74916" FT /note="SPCC757.05c, len:400, SIMILARITY:Caenorhabditis eleg FT ans., Q18622, similar to e. coli acetylornithine deacety FT lase, (244 aa), fasta scores: opt: 420, E():4.6e-23, (38.5% FT identity in 213 aa)" FT /gene="SPCC757.05c" FT /product="putative acetylornithine deacetylase; peptidase FT M20 domain; putative succinate metabolism; no apparent S. FT cerevisiae ortholog" FT /protein_id="CAA21230.1" FT /translation="MTMKISVWSLLIVIGYHLWMSPVLAGPLNFGYLSWGQHSILEQDS FT VQLISHQSLLPAGDNLISLHKSLVEIESLGGNEVNVSDFLKSYLESKGLTVELQRVSSN FT PTVRDNVYAYLGSQRNTKVVLTSHIDTVNPFLPYYIEGDKIHGRGSCDAKSSVAAQIFA FT MLELMSEGKVQEGDLSLLFVVGEEIDGIGMKTVANKLNADWEVAIFGEPTENKLGVGHK FT GNFRFDVYAHGKACHSGYPQEGFSAIEFLLRQCVKLMDTDLPKSKLLGPSTINIGTIEG FT GAAANILAAEAKAEVFIRVAEDIETIRDIAEDLFDTEHSEIKVIQYSPPQYLDYDIPGM FT DTVVLAYATDIPYLSDRKMKIYLFGPGSIREAHGPNEYVTFSQLFEGLNGYKRMVMYNL FT R" FT misc_feature complement(8969..9820) FT /note="Match to PF01546 Peptidase_M20, Peptidase family FT M20/M25/M40 Score 125.97" FT CDS join(11482..11511,11569..11682,11726..11932) FT /db_xref="SPTREMBL:O74917" FT /gene="SPCC757.06" FT /product="very hypothetical protein" FT /protein_id="CAA21231.1" FT /translation="MVNPDKTSRVYCKYTCCGYVGSLDHDKQDAHVCKLGCQLFYGESC FT YKEMSNALNGTSRPIFLLSVPAIEVAQLQTLGEMSLKFLIKLIVKMTDCPRQSFSCSEL FT ITVLPTVQKLTF" FT misc_feature 11512..11517 FT /note="gtgtgt, splice donor sequence" FT misc_feature 11554..11568 FT /note="ttgatatttttccag, splice branch and acceptor" FT misc_feature 11683..11688 FT /note="gttagt, splice donor sequence" FT misc_feature 11705..11725 FT /note="ttaatttcggcaaaatcaaag, splice branch and acceptor" FT CDS complement(12830..14368) FT /db_xref="GOA:P55306" FT /db_xref="SWISS-PROT:P55306" FT /label=ctt1 FT /gene="SPCC757.07c" FT /gene="cta1" FT /product="catalase" FT /EC_number="1.11.1.6" FT /gene="ctt1" FT /protein_id="CAA21232.1" FT /translation="MNSKDSNTVPVYTTNTGCPIFNPMAAARVGKGGPVLLQDSHLIDV FT FQHFDRERIPERVVHAKGSGAFGEFECTDDITKYTKHTMFSKVGKKTPMVARFSTVGGE FT RGTPDTARDPRGFALKFYTDEGIFDMVGNNTPVFFLRDPAKFPLFIHTQKRNPQNDMKD FT ATMFWDYLSQNAESIHQVMILFSDLGGTPYSYRFMDGFSSHTYKFVNDKGEFYYCKWHF FT ITNQGTKGLTNEEAAALDGSNPDHARQDLFEAIERGDYPSWTLYVQVMTPQEAEKYRYN FT IFDLTKVWPHKDVPMQRVGRFTLNQNPTNFFADIEQAGFSPSHMVPGIEVSADPVLQVR FT TFSYPDTHRHRLGANFEQIPVNSPKCPVFNYSRDGPMNVNGNQGNWPNYPSSIRPLAKV FT QYEPDEGHEKWVGQVTYHMDEITDVDFEQPRAFWQNVLGKKPGQQDNFVKNVAGHLSGA FT ISPVRERQYGVFTRVDSELGRRIREATEAEVKKMEEKAPKPINKGEPHMFQGSS" FT misc_feature complement(12911..14332) FT /note="Pfam match to entry PF00199 catalase, Catalases" FT misc_feature complement(13325..13351) FT /note="PS00437 Catalase proximal heme-ligand signature" FT misc_feature complement(14174..14224) FT /note="PS00438 Catalase proximal active site signature" FT misc_feature complement(14369..18901) FT /note="putative gene-free region" FT misc_feature join(complement(16677..16736),complement(16451..16606), FT complement(16335..16393),complement(16142..16163)) FT /note="NOTE:possibly a gene here but can't get a good FT prediction; introns have good scores though. May be a FT pseudo?" FT intron complement(16164..16334) FT /note="Intron predicted by HMM_intron, Score=7.18" FT intron complement(16394..16450) FT /note="Intron predicted by HMM_intron, Score=12.11" FT intron complement(16607..16676) FT /note="Intron predicted by HMM_intron, Score=16.24" FT CDS join(18902..19065,19120..19239,19339..19930) FT /db_xref="GOA:O74918" FT /db_xref="SWISS-PROT:O74918" FT /gene="SPCC757.08" FT /product="putative exosome 3'-5' exoribonuclease complex; FT involved in 3'-end processing of multiple small RNA FT species; similar to S. cerevisiae RRP45" FT /protein_id="CAA21233.1" FT /translation="MSRHLETSLNNKEFVLNSLEKGLRLDGRQLSDFRSLEIQFGKEYG FT QVDVSFGHTRVMARITTEITKPYTDRPFDGIFSITTELTPLAYSAFEAGRVSDQEIVIS FT RLIEKAVRRSNALDTESLCIISGQKCWHVRASVHFINHDGNLVDAACIAVIAALCHFRR FT PELTVVGEEVTVHPVEERVPVPLSILHMPICVTFSFFNNGELAIVDATLEEEDLCNGSM FT TITLNKNREVCQIYKAGGIIIDPSKIISCAKTAFDIAVSVCSVIQQALDEDLRKKETQY FT LGGSAENERS" FT misc_feature join(18971..19065,19120..19239,19339..19807) FT /note="Match to PF01138 RNase_PH, 3' exoribonuclease family FT Score 127.44" FT misc_feature 19066..19071 FT /note="gtatat, splice donor sequence" FT misc_feature 19104..19119 FT /note="ctaacaagtactgtag, splice branch and acceptor" FT misc_feature 19240..19245 FT /note="gtaaga, splice donor sequence" FT misc_feature 19326..19338 FT /note="ctaataatcacag, splice branch and acceptor" FT CDS complement(21392..22588) FT /db_xref="GOA:O74919" FT /db_xref="SPTREMBL:O74919" FT /note="SPCC757.09c, len:398, SIMILARITY:Saccharomyces cerev FT isiae, YBL032W, YBD2_YEAST, hypothetical 41.7 kD protein in FT rib1-aac2 intergenic region., (381 aa), fasta scores: opt: FT 187, E():5.1e-18, (27.9% identity in 340 aa)" FT /gene="SPCC757.09c" FT /product="RNA-binding protein; contains KH domain; putative FT polyadenylation factor; similar to S. cerevisiae PBP2" FT /protein_id="CAA21234.1" FT /translation="MAYNHFSIPKNIEEKENSFFDVTFQDEPDETTSTATGIAKVSIPT FT PKPSTPLSTLTNGSTIQQSMTNQPEPTSQVPPISAKPPMDDATYATQQLTLRALLSTRE FT AGIIIGKAGKNVAELRSTTNVKAGVTKAVPNVHDRVLTISGPLENVVRAYRFIIDIFAK FT NSTNPDGTPSDANTPRKLRLLIAHSLMGSIIGRNGLRIKLIQDKCSCRMIASKDMLPQS FT TERTVEIHGTVDNLHAAIWEIGKCLIDDWERGAGTVFYNPVSRLTQPLPSLASTASPQQ FT VSPPAAPSTTSGEAIPENFVSYGAQVFPATQMPFLQQPKVTQNISIPADMVGCIIGRGG FT SKISEIRRTSGSKISIAKEPHDETGERMFTITGTHEENEKALFLLYQQLEMEKDRRSH" FT misc_feature complement(21470..21619) FT /note="Pfam match to entry PF00013 KH-domain, KH domain fam FT ily of RNA-binding proteins" FT misc_feature complement(21896..22045) FT /note="Pfam match to entry PF00013 KH-domain, KH domain fam FT ily of RNA-binding proteins" FT misc_feature complement(22154..22300) FT /note="Pfam match to entry PF00013 KH-domain, KH domain fam FT ily of RNA-binding proteins" FT CDS join(24515..24856,24920..25138) FT /db_xref="SPTREMBL:O74920" FT /note="SPCC757.10, len:186, LOW SIMILARITY:Saccharomyces FT cerevisiae, VM12_YEAST, vacuolar atpase assembly integral FT membrane protein vma12, (215 aa), fasta scores: opt: 164, FT E():5.7e-05, (29.5% identity in 105 aa)" FT /gene="SPCC757.10" FT /gene="vph2" FT /product="putative vacuolar ATPase assembly protein; FT similar to S. cerevisiae VPH2" FT /protein_id="CAA21235.1" FT /translation="MLKELRLHNRNINFLEFLRGVQIVPSDSVFLGEIDENSHTQDNTT FT TSILKEKELYDGIPLLPSMAGVSMDPEREKKSELRLMKNQISAIINILFTVVGTVTAVW FT YCTSSLSIEKKIALCAFSAILVLVADTFLYVRYLSAQPVRTSKNHTRQIIYTWTTNDPV FT LQSNEQLAIELGAIPSLKEKKNQ" FT misc_feature 24857..24862 FT /note="gtatga, splice donor sequence" FT misc_feature 24901..24919 FT /note="ttgacttaatattatttag, splice branch and acceptor" FT CDS complement(25544..26959) FT /db_xref="SPTREMBL:O74921" FT /note="SPCC757.11c, len:471, SIMILARITY:Schizosaccharomyces FT pombe, Q12519, hypothetical 56.1 kD protein., (500 aa), fa FT sta scores: opt: 1176, E():0, (40.6% identity in 443 aa)" FT /gene="SPCC757.11c" FT /product="conserved protein; putative membrane transporter; FT no apparent S. cerevisiae ortholog" FT /protein_id="CAA21236.1" FT /translation="MEQQSNLEKDLSVSSFLDEKEKSGYKQSVRLVSNDPSASPAATHK FT PPFISAALMLLNNTILCISFTIVVPTSERFVQHLGGGNGLSGVIIGLPTITALVLLYPM FT LRFSTPKAAKGYTIYRRPYTMSCISCIIGHIMYALADKAKSVALILVSRIFTGVACTMF FT LYHKRYFTDKALISIKYRTSMGVVNSVMATLGLTAGPFIGGLMAKSSMKSQSDIWNEYT FT SGNWLMAFIWVGLFLFGFACFREVLSPQTDVKEEVVEEKHVINDVKQDTNSKLGFVGCL FT VIFVVAFSGFSAYFLLNAYQASVPIYTSMLYNYSSFQAGNFLSLAGIINVPLLLIFSYL FT TRYLTDRDIILLGCCLNIVCMVIHITIHYTGKEFVQPYFIIYTLVFFGSSIANSPSVSL FT LTKVLHPKYHLIGNVAVQISISLSDTVGAIFGGAFRSFSPVVFFAVCLILNVMSVLALL FT IIWKKLKVKLRLA" FT tRNA 27303..27374 FT /note="tRNA His anticodon GTG" FT CDS 29386..31263 FT /db_xref="GOA:O74922" FT /db_xref="SPTREMBL:O74922" FT /note="SPCC757.12, len:625, SIMILARITY:Schizosaccharomyces FT pombe, Q9Y7S9, alpha-amylase SPCC63.02C, (564 aa), fasta FT scores: opt: 1578, E():0, (43.4% identity in 546 aa)" FT /gene="SPCC757.12" FT /product="putative alpha-amylase; no apparent S. cerevisiae FT ortholog" FT /protein_id="CAA21237.1" FT /translation="MGFSKIALFSLFALFGLPTSLAKSSEEWRDRIIYQVITDRFAVDS FT DNTPDCSFDDSSYCGGTWSGIRSKLDYIQGMGFNAIWISPVEKNLEGSYGSDGEAYHGY FT WNTDFTQLNEHFGSEDDLIDLITDMHNRDMWIMFDALANSMAIPGPTDNISYSNLVPFN FT DSSYFHPYCWIDYGSNNNTDIEDCWTGDDNVILADLDIESTNVADYLHEHIHDMVERYQ FT IDGIRIDAVKQMNPEFFPNYTSAAGVFAIGEMFSYDPNVSCSVRNYLDSITSYPIRQGI FT EFAFNYTGAAFEYLQEIDTQFQQACEGQDMSVIGNFLENHDLPRYTSITNDTSQDIGAI FT VFLLLHTGIPIIYYGEEQRLPGGSDTPENRAALWNYGYDTDANYYQTIRTAIALRKQAI FT SDSDSWTTDSHSYLDYDLRHAVVRKGDVLGVYTNYESSSDNVTYDVSSNFDDGTVLREV FT LSNTTTTVGSSGALHVTVVSGLPQVYYPEASLTSFGNFLGTATSYSSASASYPSTSMSA FT SLSSVHTSSATSSSKSSSSSSSRSGSSSSSSSRSGSTSSSGSSHTITSTSQSVHTSGSS FT TSTSSVAVTSTAYSSSSSSSSSSSIESSANAVRVSILGVAAFIAIVLFI" FT misc_feature 29479..30723 FT /note="Pfam match to entry PF00128 alpha-amylase, Alpha amy FT lases (family of glycosyl hydrolases)" FT CDS 33947..35515 FT /db_xref="GOA:O74923" FT /db_xref="SPTREMBL:O74923" FT /note="SPCC757.13, len:522, SIMILARITY:Schizosaccharomyces FT pombe, O94491, putative allantoate permease., (508 aa), FT fasta scores: opt: 1083, E():0, (36.0% identity in 520 aa)" FT /gene="SPCC757.13" FT /product="putative MFS allantoate transporter" FT /protein_id="CAA21238.1" FT /translation="MSSITSRVSSRSSHELTEKKSGVTNDFKNSFEVGEVKRLPDAEGT FT ADAVAQELLADDDFTYTAKEARRVLWKIDLVMMPVMCITYMIQYLDKTALSYAALYGMK FT TDTHIDGHTYSSMTTLFYAGYLVAQYPAAILMQKCRLSYFIFCNVFLWSAMVCLMAACR FT NGPSLLGLRFLAGIFEASITPAFINITAMWYRREEQPMRTLCWYAFNGIAQIIGSILSY FT GLGHIHGKVASWRYVFIVIGLMSLGWGVVFVFIPSNPSKARFLSSREKRIALERVRDNR FT TGLENKQFKWKHAYEAFLDPQVIMITLFTGVCMITNGIGVFSTLIIKGLGYNELHSAVL FT NMPLGAIEVAAMFISGVLCKVFKNGRLLIGVFMNCLTLAGCLMIWKIPDSNPYGRLVGV FT WFTMWVPASSALLLSLISSNVAGYTKKTVTSATVFVFYSVGNIVSPQLFKSGQTPEYIE FT GIQAMIVSLCIIIAIAFVLTGYYIYENKRRDRLLAEDPSLGESIKNEEFMDLTDRQQPK FT FRYRW" FT misc_feature complement(35704..37228) FT /note="nominal overlap with cosmid SPCC613, EM:AL031644 S. FT pombe chromosome 3" FT CDS 36450..37228 FT /db_xref="GOA:O74901" FT /db_xref="SPTREMBL:O74901" FT /note="SPCC757.14, len:256, SIMILARITY:Schizosaccharomyces FT pombe, Q12519, hypothetical 56.1 kD protein, (500 aa), fast FT a scores: opt: 908, E():0, (58.5% identity in 246 aa)" FT /partial FT /gene="SPCC757.14" FT /gene="SPCC613.01" FT /product="MFS transporter of unknown specificity; no FT apparent S. cerevisiae ortholog" FT /protein_id="CAA21239.1" FT /translation="MSTTTETVTWSQYKPQETQRRLSRSSTITPSVSEYRSGFSKTAFG FT NIELEEIPDKQGNITRATSNLESNSYPKALDPDACPPKRSIALVLLNNLMSEMSLTIAL FT PISAAYTEILGGTDAFSGLVIGIPTMISLVCLYPMLRFANPKSANGYTLYFRPLIVSCI FT SQIIGHLLYSLAYRAQWLYLILIGRMCSGVGFTMFLYHKTYLTDKNFVGQNRSTFLATL FT NILAQILGSMAGAFLGGILAKASMHLTDPIWNQYTAGS" XX SQ Sequence 37228 BP; 11759 A; 6668 C; 6807 G; 11994 T; 0 other; atattactgc aattgacaac ttaacgcgcc gtttattatc aacagacaaa ccaatgtcaa 60 cagttggaac ttggttcagc attggtcatt caactgtagt ccttataact tgcatcgtag 120 tagcagctac ttccagtaag tttgcagatc gatggaataa ctttcaaacc ataggaggaa 180 taattggaac ttcagttagc atgggactat tacttttgtt ggcaattgga aataccgttt 240 tactagtccg gttatcgtat tggctttgga tgtatcgcaa atctggtgtc actaaagatg 300 aaggggtcac cggattctta gctcgaaaaa tgcagagatt gtttagattg gttgactctc 360 cgtggaagat ttatgtactt ggttttgttt tcggattggg atttgatacc agtactgagg 420 tttccttgtt gggtatcgca accttgcaag ccttaaaagg aacatctata tgggcaatct 480 tacttttccc cattgtattt cttgttggaa tgtgcttagt tgataccaca gatggagcat 540 taatgtatta tgcttactca tattcttcgg gtgaaaccaa tccttatttc tctaggcttt 600 attactccat aattttaaca tttgtttcgg ttatagcagc atttacaatt ggtatcattc 660 aaatgcttat gctaatcata agtgtccacc caatggaaag tacattttgg aatggcctca 720 atagattatc tgataattac gaaatagtcg gtggatgtat atgcggtgcc tttgttctag 780 caggtttgtt tggtatttcc atgcataatt actttaagaa aaaatttaca cctccagtgc 840 aagtaggaaa tgacagagag gacgaagttc tagagaaaaa taaagaatta gaaaacgtat 900 caaaaaactc gatttctgtt caaatttccg aaagtgaaaa ggtgagttac gatacagtgg 960 attctaaggt ttgaacgact gggaatttct gtttcctttt tttttcttca gtattctcga 1020 tttgttctct taacctgttg cttgggttaa aagtctttat gcctttatca tgatgaaata 1080 gaaactcggt tcgatattga tgatttgaat aagcagacga gccacataca ttcgtttgag 1140 gtcatatagg ttaaacagtt gctagtagca atttatttgt gtgaaaaaag aaaggcaagc 1200 aaaatgtgaa aaatttattc tttacatatt ttacatgata acaaaaaatc ctccttgggc 1260 ctggctttat gattcgggca aaataccagg gctgtatttt ttttaaaaaa atactgtgta 1320 tcggcattag cactttgctt actcaacttt tggaggcttg aaaatgcagg tttattcaat 1380 ataacatacg ggtcaaatat attacccgat gtattctaga atacttttat aaaattcttg 1440 acaaagaatt gatttcattg ggtgattcat tcattgcttg actatttgat tagtaaactg 1500 tcgaagaaaa agttgaatta gtttcttcca tttctgagat tcgaacattc ttcaaatttt 1560 ttatataaaa taaaaaatga gaaattcatg agttcgacta attttgtggg atttgtttct 1620 gtttttttaa ttcatcaaat gtctctttaa atccatcaaa ggtatcatag taatcagtgt 1680 aaccaagctt cctggctttg ctcattgagg atataacgtt gtacgtcctg ccgaacaaaa 1740 aatcacaaaa cgcccaagtc ccaacttcta aagcatgagc attgagtttt tctctttctg 1800 cgattgtcct ccaagcgtct tggactttct tttgcttgac ccattgttga agcgatattt 1860 ggtttattat tttactattg ggggtatgtt taatgccgag ctctttttcg tacagattta 1920 tgggagaagg tgtacttaaa gtaacttctg tacttaatgt aaaatccgtt gcaaattggt 1980 tttttggtac ctcgacccca aaatattcgg ctattttagg ccaagttctt gaccaactgt 2040 gaatatctcc gtttacaatg ttgaatttct cttcactgca ttctgcttta aatgtcatcc 2100 ataattgaaa atcagcaatt agctttgaat acgagatatc atcgaagccg agatagaact 2160 tttcatttcc tggaaatcgg aacggttcat gaagctccct gcaaaccaaa gcatataatg 2220 ctatagtgaa tgcttcattc atgtagcttc cttttgatac tccgcaaata tcattcggca 2280 tagctatggt gtagtcccat tttttaccgt tactaaattc tttaagaata tcttcttgaa 2340 cgtagtaaaa atttggagtt ccactaaatg tttcaggtac tcgtatgtct gtctcaatca 2400 ttggcaaacg aacttctcct aaatgtaatc cataaaattt tagaccagtg gttagaatta 2460 cgcgtctcaa agtttgaatg gaagtaagtt ctaatgcttg cacaaagttt ctcaacatgt 2520 taccgttaac ttcacacaac ttttcttcat tattttcttc tttataagct gcaaagtatg 2580 cataatttat tcccttaacc ccctcgagag aaaacttttt tgcaatatct ttgggttctt 2640 catttagcag atctatggaa tgatgcttga tttttctagg gtattcatct ttcaacgaac 2700 gagaaataca gtgtatagtt ttgcaattat catcctctga cagtctctta ataatagctg 2760 caccatttaa tcctgttgcc ccagtcacta tagccacgta accttcttct gccattgtgt 2820 ttctaacttt gaatatcttt taagaaatct cgcatatatg aaatatatat atatatatat 2880 atatatatat atatatatag catttatgct ttaatttata cccaaatttt atgatctcat 2940 tcacttttgc tatatcacta gtaacatcat ccatactata gacttgttct agtttgtgaa 3000 attcacaata gctagtgaac acatgtcggt gtgataataa cagtatgatg ttgcaagtat 3060 gtatggtcat atttgattga ggtatgaaat acaaaaggta ttttaataat gctgactata 3120 tgtagggacg ctgttagagc ttagcaagca agttgaatac agagaaatcg aggcaccatt 3180 gcagtgatgc cccttgcgac tgatggaaaa acataacaat gaatatttat ctaattgttt 3240 tagaacacct gactataaac tgttaacttt atgggaaggt tgcttggaag gttgcttggt 3300 tggatggtta aaagtcattt ttgaaacctc acaagctgtt cgtaattagt tcaaaaacta 3360 acaatctaaa ataaaaagga aataataaat aaatccaata aaatccagct actaacaaaa 3420 acaataaatt gttccactat taactctcgc tattctagaa atttaagtgt cattaatatt 3480 ggtctttaaa gctcaagttg ctatttacaa ccgtctctta gtcatcgaaa taaaactaat 3540 gatcgatctt tgaagccatc aattatacgc tttcatcaat gtcgaattca tcaaggcatt 3600 tagcaggtag agtaaaaaaa gaatcgttac aaaaatggat ggttcatgtc ttgcgaagag 3660 attgtgaaac ttttatggca gcctccgctg tagatttagc actcattgga ttcacacctg 3720 ttacaattct tccatctacc tgagtgaaat cggacatcgg ggtaggcggg tcaacgaact 3780 ctgcaccggc ttctctaaac aagctgttca gatcttgcat gttcctttct ctcaaagcac 3840 ttgatacacc cattacaagc tctccagtac tattgaaggc ggtaaccttc ttaccatata 3900 cgacggaacg tccttctggt gacttggtgt catctacaaa aggcagcata actggaccgt 3960 ggcagacggc agcaagtaca ccattgcttg cataaatttg ttgagcaagc gtttgcaaat 4020 ttgtggcatg tggtagatca aacatggctg catgacctcc tgcaataaac atgatacaga 4080 actctttgta gttaatttta tcggcaggct taatatcctt cagcgcatac caaaactcat 4140 tatccttgtt gtcaaaagca tccctctcca cttcacccaa ggcagatttt ttgattgaat 4200 ggtcgtcgaa tttacatttt cctgtttctg aagttagttg aacttcataa cccgcttctc 4260 tgaaaacttg atagggaatc aaaagttccg caaagtgaac tccagtattc attccatctg 4320 gataaaatgg tccatagtaa ctgcttgcca cgagaagtac ttttccttct gatgccatgg 4380 tgtataatga atgggtgatc tttgcagctt cacctcaata aataacaaat tttaaaaaaa 4440 catcacttaa ttgcaaaagc gggatgaatt tccattacga ctactcacgt aatctattta 4500 ccaggttctt ggatttctat agaaagagtg acgagggcat tgtgtcaata tgatgttaaa 4560 ttcatcttaa aatcagatgg atacgtttga atctaaagtg gtttcggcac aattctattc 4620 tattgtgtag aaggacattg cgatcgctac tgagaaaatg caaatctctt tgtattgttt 4680 agtgtataag tttcatcttg atttgagaga tttgcttcaa ggactttttg ctagtttcaa 4740 ttatcatcat gattttcctc atacgtttta ggattgtgag cgatgcgtaa ttaaaatttc 4800 gtagtctatg attgtgaacg gaaatttttt aaagtacttt attactatat gaacatacca 4860 agctagaatg ttgctcgttt caaaagacaa ctgtaaattt gatctattca attggagttt 4920 attgaatatt cagataaaat aagaggttta agtttttttc atttacactc gccaaccgca 4980 actttaatta tattttttct ttttttgctc ttcagtatgc cacgttatac tgttttacgt 5040 ttagattaga gctcgaataa ttttatacca acaacgcctc tatattcgaa atcattaaaa 5100 agataagatg tcaactactt acattgcgct ataatacact gcgttgcgta tcactatatg 5160 tcatatgtta agatactact gcaccacaca ttagtgaaaa gcacagataa actatctgtc 5220 tatctacata gatagcaact attagaaaga ttataaatag agctacaatt gaccctcgtt 5280 tctcatttca gttattagct attagctata tggtcaccga tactaataga cttcatataa 5340 caattaatat acattgttag ttaaatattg cataccgcta tattgtaggt cgcaaataaa 5400 actcaccgca gttctatgta tcgttaaaca ggttccaaac agcgtagctg acagaaactg 5460 tattttaatt gtctactgaa acataaaaac agttgattga gaatatattt tgcccaataa 5520 aatattgaaa gttctggatg tgttccttgc ttgcaaaaat ttgtatttcg ttctttctct 5580 tacactcatt cgtaacttat acctactaaa caatcgtggc gactgtgtgg ataacgtata 5640 tgcggaaata tactacaatt gaatttgcca tggtctttac cgtgtttaat taaatgtggt 5700 ttctaattgt ttcatataca tttcaattga ggggatacta gagaaacgta aataatgagt 5760 atcccatttt ttactggaga aacaacatat tcatttgctt cttgcgtgag ctattcagga 5820 cattattgtg tttccatata tcccatttga tattaaaaga attattctga aaacgaaaac 5880 attgtttact attgcactag ttaaccaacg tttgtttacg ctttaaagca gttttgcaca 5940 agtgcatttt cttgatgttg aaaagtagac tttcacagat ttagatctct tttagtaaga 6000 aaaaaatagg gtaataaata aattttttta aactactttt tattaagcgt ttttgatgtt 6060 gaggttttta ggaataaact ctgctagtat tatttcaaac attaaccatg cgtaaatttt 6120 agtaccaaca tttgttaatc atatatgtta acgatactta gcaagtcgat atttatttag 6180 tgaagtttag gaatgtcggt tacggcgaag attaatttca ttactgtcgg ctaacctctt 6240 ttatttcagt atttggacta atgagccaca tggatagtga acgcttgctc ttcaaacgct 6300 atttacaaag attattcatc acgagaatac ttacgttgat caggttagat ttatctcttt 6360 ttagacgata taataccaat actatcgttg gatctgttgc atatgaaaca ttagtggata 6420 cagtttgcga tgtctcatcg aattcgacat ttgtcgtaag tagatttaca tgttttcgtt 6480 tttcggtctt ttctaactaa acagatgttt agcttgccgt cggaagaagg tacctttaaa 6540 ttttaaaaat ctactttaag ctaatttaat caatcgacag gtaaaatgca atcgacagta 6600 tccttgcact aggtgtctga agtatggcga ggcgtgtact tatgatgagc gagacaatag 6660 gaagaaaagg cactctctta gttatcttca ttcattggaa agtcagttgg ctcggctgga 6720 atcttttatt atgactctta aaaattcgga tcctgaagga cgagatgaga tgttaaaatc 6780 tgtagtcttt tccgaccacc ttacagaacc aaatgaccaa gaagttaaat ccgaaggccc 6840 aattgagtat cctgtctttt tgaatgttca agattcgaag acggtatcct tttatggacc 6900 gacaagtgcc tatgatctat ctttgccaga tatcacaaaa gacaacaaga ctacttggaa 6960 ttttcaagct tcttattctc ccatggtatc agaatgctta aagttgtttt ttaggtatca 7020 atattctcaa tttctctttg tataccggga gtcgttcctt tcagactact attacaattt 7080 tcacgatggc ttctactgca ctgaacatct tatttatgca atttgcgcta ttggtgccag 7140 tatgtcagat gacgaaaata tatcccgcca ttcgaagtcg tattatgatg cttcttggca 7200 aaaactttta gaatttggat tagatcgctc ccatttaact tccgttcaat gtctgttatg 7260 tctggggtat tatgatattg ggatgggaaa tacttcactt ggttggttat tatcaggctt 7320 agcctttcga atgggtcaag acttgggctt ccagttaaac ccagaaaatt ggtatatcga 7380 caattcgcct gctatttcct ctgcagattc tgatataagg cgacgtgttt tttggggcag 7440 ttatgtggct gataaattta tcggcttcat tatggggaga cccacgatgt taaaacggtc 7500 ggacgccagt attccgggat ctaatcagtt gccggaattt gctgggctcg aagagtttaa 7560 acttaacgta acagattata tgagcttgac ggacttttct gtctgtgatg ctgtagctct 7620 gttcgttgac ttaagtgaca ttgcagattc aattttatta aatatgtttt cgcctactag 7680 caagaatcgt gccactaata tcaattgcgt tttgagtaat cttggaaaat ataatttaga 7740 gctaatgaat tggcactata aactacctga tactattagt tggagaacca ttgatttaaa 7800 aaaagatcgc atacctaatc tttgcgctgt cagcctatac taccacttaa ttcgcatttg 7860 tttgaatcgg ccattcctgt ccaggaaaga agtgaccgct aacgatctta caccaaaaac 7920 tatatgtact gattccatca acgaaatagt aactgttata cgagcacacc gtactgcaaa 7980 tggccttcga tactcgacac tatacatagt gtatgcggcg attgtcagtt gcagtgtgat 8040 tctactactt cgagatatgt gtactgattc agagcttttg acattgaata acgatatgat 8100 gtttttcatt gaagttctta aagagtgctc tcaaacttgg aaattggctc aaagatcgat 8160 tgttctcata gaaaacacac tgaaaggaaa aacgaatagt caatctacgt ctgaatttgt 8220 atctccaatt agcgatactg aaaacggctc ttcatctcag caggttagcg aggctaagga 8280 catagtagag ccatcggacg tacttgatga attacagaaa tttgatttgc taccagaaaa 8340 cgatgacaac ttccaaacat ttcaagcatt ttatggtgga cctcctatca tactatctcc 8400 gaatttatac gaaaagaagc tcaatgaaaa aaccttatag ttaacgtaat atttattgtt 8460 agaattccct ctttattatg tgcgaaccat atgttagcat ggacagatta cttaaatttt 8520 atacagtttt ggacgatgca tgctgctgca ttatttaatc ctattttatt tccacatgga 8580 gagatgggct aaacgatatt gccgctatat gtttgttacg gattcggcaa ttcagtgaca 8640 cacaattaat aatcatgtat caatttttaa agtaaaagac taacttaatg agctgatgat 8700 taattttgat atctatgaaa ataattaata tgattagagg tcaatatagt acatcgggca 8760 tcaccaaggt attgtacaca tacaaagaat gatgttatgt aattgaaaca cattaacgta 8820 aattatacat aaccatgcgt ttgtaaccat tcagaccctc aaagagttga gaaaatgtaa 8880 catactcgtt tgggccatga gcttcgcgga tggaaccagg tccaaataaa tatatcttca 8940 ttttcctgtc acttaaatat ggtatatcag tagcataggc taaaacaacc gtatccattc 9000 cgggtatatc ataatcgagg tattgaggag gtgaatattg gatgactttt atctcagaat 9060 gctcggtgtc gaacaaatcc tcggctatat cacggattgt ttctatatct tctgcaactc 9120 taataaatac ctcagccttt gcttcagctg caagaatatt cgcggcagcg ccaccttcta 9180 tagtaccaat gttaatagtg ctaggcccca gcaacttaga ctttggtaag tcagtgtcca 9240 ttaactttac acattgtcga agtaaaaact caatggcact aaatccttct tggggatatc 9300 cagaatgaca agctttgccg tgagcataaa cgtcaaacct aaagttaccc ttgtgtccta 9360 cacccaactt gttttcagtg ggctctccaa atatagctac ctcccaatca gcattaagtt 9420 tattagcaac ggttttcatc ccgataccat caatttcttc gcctacgaca aacagcagcg 9480 aaagatcacc ttcttgaact tttccttctg acattagttc caacattgca aagatttgtg 9540 cagcaactga actttttgcg tcacaggaac ctctaccatg aattttatcg ccttcaatgt 9600 agtagggtaa gaaagggttg acagtgtcga tatggcttgt cagtacaacc ttggtgtttc 9660 tctgactacc tagatatgca tagacgttgt ctcgcacagt cgggttagag gagacacgct 9720 gcaattcgac ggttaaaccc ttggactcca agtaggattt taagaaatct gacacattta 9780 cttcattccc accaagagat tctatttcaa ccaaagattt atgaagagaa atcaagttgt 9840 cgccagctgg caataatgat tgatgtgaaa taagctgtac agagtcttgt tcaagtatgg 9900 agtgttgccc ccaagacaaa taaccaaaat ttaggggacc cgccagtacg ggtgacatcc 9960 aaaggtggta gccgataact attaaaaggc tccaaacaga aattttcatt gtcatacaat 10020 aaacgttatt tttgaattta tgtacaatag gcagacggtt attgaactcg agcagtaatg 10080 ggagtgttca tgattttatg gtgtagtagt agcctatcta ttatctaact tccaaatttt 10140 aagcgacaac ccttggtagg cggtaacaat ttgattagga taactaatat aaagaaggat 10200 tgttttatgg ttgtattaaa atataaacgc tgaaattagt actaagtgca gataccagtg 10260 cttaagacgc tgatttagta tttgtgtttg cctgatttat acatgatttc gttaatcagc 10320 gttaagtcag cgtcatactg gaagtcagct caatggaaat acttacatta aacattacta 10380 tattatacaa agaggagtaa ataaattttg gatagtaaaa ttaaatttaa aaaatctcaa 10440 caggtgataa gaaactgcaa tgcttgtagc gacaaattat ggtaatgtgc tcagcttttg 10500 tattattgac aaaaagtata cagtaataaa tacacccata accctcaaac tattgtttac 10560 tatcaaaaga atctaacagg aaaagctatt aaaagttttt taagagaaac aagtaaaacg 10620 aggtaagtac agaaaaaggc tttatacgca ctcaatcgta ttgaagcaaa gttggaaccc 10680 ttctgcgatc tgaaacttgc aatgaagtaa aggaaaaaag ccatactgtc gagacgatgt 10740 gtataatgtc ttaaagaata aaactccgta aaatattaga atattgacgt cggatatgtc 10800 ccctcggtta acaaaacttt aaacttcatg aatttaggaa tattgcgggg agggaataca 10860 ttaataattc aaacaatagg agaaagaaat ctttgacggc acactcaaga ataagtcatg 10920 gactacggac taaaattatc aaatttctca gtaacttaag ttgttttttc gttccatcat 10980 cttacgaagt agattggttt aagtataaat agatcgatta gatctagtgt catttagatt 11040 tgttttccag tatttcaagg tatatcttat tgccaaattt tactcaaatt ttgttaaaat 11100 tgaagaaaaa ttggacattt caattgaatg ctactgggca tatccaattt acgatttccc 11160 taaggttctg taagatcata aaacactttt cttttgcaaa ccttcataat ttctattcac 11220 tcatctctgg aatcattaat tatactctcc ctactagaat cttgtatttg taagtttgct 11280 attggtttgg ctatgttgag tgaagtgcct gcccttaaaa ttgggatact taaaataaat 11340 tggaagtaac atcagctaaa atattttttt accttttatg aagtaataaa gtcatcggaa 11400 atgcttgact atgcacatga gaacattgcc atagatgatt gctggaagac gaaggagcgt 11460 caagccatca ctaattaact aatggtgaat cctgataaaa cctcaagagt ggtgtgtttt 11520 catggctcag gaagtccata attaagtttc aagttgatat ttttccagta ctgtaaatat 11580 acttgctgtg gctatgtagg atccctcgat catgataaac aagacgctca cgtctgcaaa 11640 ttgggttgtc aattatttta cggagaatct tgctacaaag aagttagtgt caaaaactct 11700 ttaattaatt tcggcaaaat caaagatgtc aaatgccctc aacggaacta gtcgtcccat 11760 ttttttactc tcagtgcctg caattgaggt agcacaatta caaactcttg gagaaatgtc 11820 gttaaaattt ttaataaaat taattgtaaa gatgactgat tgcccacgtc aaagcttcag 11880 ctgtagtgaa ttaattacag ttttacctac tgttcagaaa ttgacatttt agcaacggct 11940 gttctttaag gacaaaaagc tacctcttct gatattcttg aagttataaa atggtataaa 12000 ctgccaccaa attcactatg tcggctttct atgataattc ctctaattct tcacaatgat 12060 gttacaaata cgcctcaaga agatttctat catcatcagc aaagacgtta tatctataag 12120 ccaagactga atttaaaact atttatgaat gcatatagcg ctaatgatgt cgatggagac 12180 actcgagttc tcccaatgtt ttttaaataa tgacagggtt gtttcgagta tgattattac 12240 gagtagttca tgttaatagt tattcgaaaa tttcattgat aaaccggcca aacctcaact 12300 ggctttgaat actagagact aaaggaataa taacaccatg agtgacaaat ttattcaata 12360 taatatttcg gcttgtttta caaagataca aatactgcaa aaaacataaa tctaatgcac 12420 atgacaactg gctttaaaag tgctaattta ctgttgctag ctacataagt aatcgaatat 12480 cgtgtgtggc tcatgaattt gcttttaagc tttcctaatt gattacaaaa ttttaatctt 12540 cctttcctca tctggtacag atattaagaa atttacggca gaagacttgg aaaacacaat 12600 aagccttaga ccttatttat atgttaacct aatatgtcaa gattgtttgc tttcttatca 12660 atgttatgtg cttattgagg ttaaaatata tatttcctaa ttaacattta tcaaattaaa 12720 taaatttcta acggcattac acatgtctcg cattcaaaga ataaaatagt agtcatccga 12780 taaacctagc tgactcaaat tttttacaaa ctaatttcgc ataagcgcat tatgagcttc 12840 cttggaacat atggggttcg cccttgttaa ttggcttggg ggctttttct tccatcttct 12900 tcacttcagc ttcagtagcc tcacgaatac ggcgaccaag ctctgaatca acacgagtaa 12960 atacaccgta ttggcgttca cgtacaggag atatagcacc agacaagtga ccggcaacgt 13020 tcttaacaaa gttatcttgc tgtccaggtt tcttgcccaa aacattttgc caaaacgctc 13080 taggttgctc aaaatcaacg tcggtaattt cgtccatatg gtaagtaact tgacctaccc 13140 acttttcgtg accttcgtca ggctcatatt gaactttagc aagtggtcgg attgaggatg 13200 gatagtttgg ccaatttcct tggtttccat tgacattcat agggccgtca cgagaatagt 13260 taaagacagg acacttagga gaattgacgg gaatttgctc gaaattagca cccaaacgat 13320 ggcggtgggt atcaggatag gaaaatgtac gtacttgcaa aacaggatcc gctgagactt 13380 caataccagg aaccatatga gaaggagaga acccagcctg ctcgatatct gcaaagaaat 13440 tggtaggatt ctgattcaag gtaaagcgtc caaccctttg cattggtacg tccttatgag 13500 gccagacctt agtaagatcg aaaatgttgt agcgatattt ttcagcctcc tgaggggtca 13560 taacttgaac gtaaagcgtc caactggggt aatcaccacg ttcaatagct tcgaaaagat 13620 cttgacgagc atggtcggga ttggatccat ccaatgcagc ggcttcttca tttgttaaac 13680 ccttggttcc ttgattagta atgaaatgcc atttgcaata gtagaattca cccttatcat 13740 taacaaattt gtaggtatga ctggaaaagc catccatgaa acggtagcta taaggggtac 13800 cacccaagtc agagaaaaga atcataactt gatggatgga ctctgcgttt tgagaaaggt 13860 aatcccaaaa catagtagca tccttcatat cattttgagg gttacgcttc tgagtatgga 13920 tgaagagagg gaatttagcg ggatcacgaa ggaagaagac aggggtattg tttccaacca 13980 tatcgaaaat accttcatcg gtgtagaact ttaatgcgaa cccacgagga tcacgagcag 14040 tatcaggagt acccctttca ccaccgacgg tggagaaacg agcaaccata ggggttttct 14100 taccaacctt agaaaacatg gtatgtttgg tatacttggt aatgtcgtcg gtgcattcga 14160 attcaccaaa agcaccggaa ccctttgcat ggacgacacg ttcaggaata cgctcgcgat 14220 caaagtgttg aaagacgtcg attaaatggg aatcttgaag taagacagga cctcccttac 14280 ccacacgagc cgcagccata gggttaaaaa tgggacaacc ggtgttggtg gtgtaaacag 14340 ggacggtatt tgagtctttc gagttcattt cgctgatgtt tgaatcctta gactgagaag 14400 atgcaaatct gttaaagagt agcttattat tgttaatctt ggaattagtt gaacgacgag 14460 caaatgattt taaactagct tgtctaccaa gacagtaacg ttcaaagatg cgaaaagccg 14520 acactttgaa gagttaggag gggaaaaaaa aagacagtca aaaaattgtg tttttttaaa 14580 aaattagtgt cgagtcttta actaaatcac tcaagacaca accacaattt ctataattcg 14640 atattcgaac aagggaatta caatcacaca cacacaaaga agaacttata gtattcttct 14700 attcaaaagc tattactttt acgtgaaaag ctgtatattc aagcaacttg caattgcctc 14760 tatatatatt gtctggtgta gaattaccaa cgtcatattt gcacaatagg aaaactctta 14820 ccaacgcaaa tggccgagat tccattggct tagtgagcca aagagcatca ttattagcga 14880 agctacaatg acaaattaac ttcttctaca gcctatcgta gtcgccaaaa tccacccttc 14940 agccaatgtt tacgatgcgc tcataccgtt acttggccat atcaaatctc ccaacaccat 15000 cgctaacgta agcgggcaaa tcccatcgtt agcgattagt aaaaccagcg tttctagaca 15060 cagacgctga catgaaattc tactgcaagt cgatatagag gagaaagatg cttaataaaa 15120 ttaaaagcta gacttttcag tcgcaaactt gtgctggaca tgcacccttt ggaaccagtg 15180 tttttggtag attagcagag tatagtgtgt ttcctgggga agtaaataaa acagatgtat 15240 ggtaaaatag gatatgcaag catgtagatt ttggcctgta ttcatgcggt ttgtttagct 15300 tgaagaattg atttcacaaa agtatggttt aatttcaaat gatgtcgggt tgatgtgcta 15360 agatcgggaa atgggtgagt gagaaaagga agttatggta attttatgat cgattagttt 15420 ggaaacgtgt tttatgggcg cattgtatat ttcttaaatt ataaattttt tctattctat 15480 attaactgaa ctgagaaagt ggattcattg tgcacagctt cccgtagagg tataatgtgc 15540 acaaatcgga agtatgacta ggagagtgaa atagataagg aggttactga aattagaata 15600 ctttcgtcca atatacttag gagtgcaagt ctaaggtcga agaaaggctg gaagtgaaac 15660 aagtcccttg cttacaaaaa aaaaaaaatg ggagatgcaa acaatctaag gaccgacaaa 15720 ccgtaggtat ggacggcgtg taaaggcaat ccgtaggaat gtgtgaaata gaatatgata 15780 cgtttaataa aagtccttct tttcctctac atcacaaatt tcaagcaaaa cgaagtaata 15840 ataataagga attttttctt tcgttggtct gactaatttt ttaggttcga tataaacact 15900 acgatttcca tgcatgtttt aattcagcgg atgaagatat aacccatacg ttgttgtttc 15960 ccatcgctca ctctacattc gcttaaataa actactacca tttgactcgt caaacaaaga 16020 ttgaaggtgg tattcacaag cttgttttat gttgaattca atttttagtt ggtaaaagta 16080 ctttaagcat aaatgccatt aactgctgtt catgaaagag gggacgttat aggtggcaga 16140 attaaatttc actatataga gaactatagt gttttttggt catcatcagt aagtgcagaa 16200 acagcatcaa cttagtaaac aaaatagtta cttagatttc gctttattct ttatttccct 16260 ctccaagact tcacaaagtc ctcgaaaatt cacgatgctg atagcttcag cttttcagca 16320 ccattttttc ttacttgagg gcgagttgat taaattcatc ctctgcaaat ccttcttctt 16380 ttatcttttc tctctagaac gtttgaaaaa ttagttacac acgtccaatt cccttagttg 16440 gaattcatac ctgttgaaac tcttgcaatg ctgctaaacg ccgttgccta tgagaataat 16500 aagattggcc aagaagaaca gtgcctccaa cagtgccgaa aattagaatc gataccgatc 16560 ccttttgtac aatgtcgtaa attcgatttc tgttcataac actgacctag tagttgttag 16620 tagtcgtgtt tgtcagttta ccacattaca cagcctaatc gcttcagtaa acttactgag 16680 ttttctttat aatttaatat gttgttaatg attattagca ctgatggaat gtgctcttaa 16740 aaggtcacct ttagtggcaa agctctttac agttgggttt tgtagaaatg aggccttccc 16800 atattctacc ggctttccga gctgtaccat gacgttcttt aaaatgatta acaggaggtt 16860 tgaaagtagt gctaaattac gttaaaactc aacatgatta attcattcgt ctagtcatca 16920 ctgctcggct cactaatatc gttggtaagt aataaagcga taaagggatc gaattattat 16980 tttaaaaagt attccggtgg gtgatactat tcattcatta ttagaaataa atcgcaagcg 17040 tttgttgtaa atgaaggtgt ctcagttatt tcctggataa taaaagttga atctcaaatt 17100 tttttcatct caatacttaa aaaataaatc ttgttactga gtgtcatagt cgctacatag 17160 gattcataaa ctgcaacttt tatttatctt tttctaagca cattagcttt aaacggatcc 17220 gtctgccgcc ttgagtaaat cagccaaaga tttataaagc caaattattt ggccttaatc 17280 aatgtatcga gtcaagtcta gatgtagcct gttcagtaac gaatttgacc ccatttttcc 17340 aagagaaaaa aacggccggc atttacagag tacaacatat gaggtaccaa agaagaaatg 17400 taaagtttaa atgaaataat tcaatgatga aaatgatcca atatgacgaa aaaaagtttc 17460 tatactattg aaattgaaga aaagaaagca ggcaaatttt acgtgttgaa gtatgtatac 17520 gtctaccttt atagaggatt acacaaacgt ttactttgga tttcattttc aattattttc 17580 aattttcttg atcatttttg gtcacttttg tcaattctga aatacgtttg ctcttcatat 17640 acttattgtt gatgtactaa gtagctgagc atttcggtaa gtcaagcaag agcaaaactg 17700 aaattgacga aataaaaact gtctcttatt agtaggaata gaaatagaaa taaatgactc 17760 acaaagcctt aagaaaattt gttttaaaat cttatgaact attaaatttc aaaggttttg 17820 tttattttca taatcgtcga ttggtgttcc tggtatcgat attaaaacag caactagttc 17880 cttttcatat cacggtctag ctaattctcg aattgcttct ttttgaatgt tcttctagga 17940 tttactcttg cttgtggtaa gattgcaaca aatgacaatg agcagtagta aatatagtac 18000 agtgcagata ttgcttttca aattaaaatt taggtgaacc tcaaacatga tttcatttat 18060 ggcatgaaat tgatggttac atttcataca attatcagag atattaaagt aacactaagc 18120 agttcatttc ggtaagtttt cgatcatctt tattatcaag ataaccgaaa caaccttagt 18180 agctgcgtca atacactcac tactcagtga caaaacaaaa tttttaggaa aattaagcct 18240 ttgtcgtttc ttcctccaaa gtcattttca tgtttactat ttccacattg ccaaaattgt 18300 tagtaacctc tattacgtgg ttataaaaaa gaattaaaat atatccaagc cgacttagca 18360 aggatatgtc ttttcataaa ctcacatacg gttttcaacc cgatcgttta acatcacgat 18420 tctaacccta tacacctaat acagtgggta aaacgcaaag tctctaaatt tgatcttatg 18480 cattccatac acagtttagt caaaatcttt taaacctata caactgacgt aataaaaaag 18540 acagcaatat ataaattaaa aattcaagcc atttcaataa agcttgaaaa ccacaaatta 18600 taacgaaatt tactgtaaat aagtctaacg ccttaatgtg aataaaacga ttgttaacgc 18660 aacagattcg acgcaaagta tagtagataa tttaagcaaa cttgtaatat tggagtaact 18720 taggcctact cgatcaagag tcgtctttta tatcaacttg gaaccttata gtggatttgt 18780 ttttgcgcac attgcgttcc ttaacttgct tcgctagtaa gcacacacac tcgtagcagc 18840 acaaattttt acggtaatat tttggatcgt tggatacaca tatttaagag actttaaaaa 18900 aatgtcaagg catctggaaa cctcccttaa taataaagaa tttgttttaa attctctaga 18960 gaaaggtctt cgattagatg gtcgacagct gtcagatttc agatctttgg aaattcaatt 19020 tggaaaggaa tatggacaag tagatgtttc atttggtcat acaaggtata tttttctctt 19080 tttttaataa tgaacagctt ttactaacaa gtactgtaga gttatggcca ggatcacaac 19140 tgaaattaca aaaccatata cagacaggcc atttgatggc atcttttcta ttactactga 19200 actcactcct ttggcatatt ctgcatttga agctggaagg taagaaatga tctgtattgt 19260 acttttactt ttgtcagccg aagggttgat tcagtggctg tttttttttt ccacctaaca 19320 acatactaat aatcacagag tttctgatca ggaaattgtt atttccagac taattgaaaa 19380 agcggtccgc cgatccaatg cattggatac ggagtcctta tgtataatat ccggtcaaaa 19440 gtgttggcac gttcgtgctt cggtccattt tattaatcat gatggaaatt tagttgatgc 19500 cgcttgtatc gcagtaatag ctgctctttg tcattttcgc cgacctgagc ttactgttgt 19560 gggtgaggaa gtgacagtac atccagtaga agagcgtgta cccgttcctc tttccatatt 19620 gcatatgcct atatgcgtga ccttcagttt cttcaataat ggcgaattag cgattgttga 19680 cgctacttta gaggaagagg atttgtgcaa cggaagtatg actattacac tcaacaaaaa 19740 tcgagaagtc tgtcaaatat acaaagcggg aggtattatc atcgatcctt ctaaaattat 19800 atcttgtgct aagaccgcat ttgatatagc tgtttcggtt tgttctgtta ttcaacaagc 19860 tttagatgaa gatttacgga aaaaagagac acagtattta ggaggttcgg cagagaacga 19920 gcggtcataa tgctagtctt ttacttaaaa aaaataaaat aaactaattt attcattcgt 19980 ttaacaaaaa attctaattg cattcgagtt cgtcgtgttg ctgaaggcgt cattccgcta 20040 agttcaagta ctaaaacaat gctttgatgg aatgggatga tatttctctt catttgatta 20100 acacttcgct atcctttttg tatttaaacc tatattgacc tatactaaat gttggcatgg 20160 aaaatccttg tacaggaaat gagaaattag gaacgcatct tgcactgaat atagctacta 20220 ctatgtacta ctaatacaag ttttttgtaa gacataaaca gtgaatgcca caagactatt 20280 tgctctttta tgtcctgaaa tattccagat attttaagat tattttcaaa attctatgta 20340 acaccgcagt tcatagaata atgtcaataa aaaaagagct ttatcacgtc ctttctcatc 20400 aaaactaaaa aaactaaaat aatatacgac gctaaaaaat aaaaagagaa gagaaaccat 20460 caaaccaacc aaatccgtaa agactagttt aaaagcaaat ttgtaatata atgaaaaaag 20520 gtatgccctt taaagtttaa aagcctttga ataaacgata atgtaaacag ctccaatatt 20580 catgcaacaa cgtatagagc tgaaaagact aataatcaac caaatatgct caaaccaata 20640 atctgaataa cgtaaaaaaa actaaaacta ctttcctata attaaaaaaa acattttttc 20700 taaaatgaac aaaaaagtag aagatgcata aaataccgat gccggattcc aaagacgaaa 20760 tgtattgatc ccgagttaaa tcaccaaaat acgtatctac gatgcgagac aatctgaaaa 20820 taagaatcaa gaatataaag gaattgaatt gctaaacaat aacgaagact gcacaagaac 20880 caaataaagg aaataattaa gatagttaaa ggggggatag aaggaatagc ttaaaaggga 20940 taagttataa acctgctgtc aaaagagtcg agtaaactaa aattaaaacc cactaagtga 21000 atagtgccaa aaattttaaa ggaaaccaaa taattttttt tcagtcctca aaaccttcgc 21060 gtgtttcaat agagaaaact ataagaacta agagacatca cacatttgaa ggcgaaaaag 21120 tagtcctaaa ctaaggaagc accactccaa aagtaagtaa aaaaaaagaa aatgaaaaag 21180 atatatgaat cctaaacaga cttgaataaa atgtgacacc actagttaaa ctaaaccaaa 21240 tttttacaaa acattgatga acgggaaagg ggaaaagcaa aaggataaac tgaaggagaa 21300 tgagcaaagt aacacaagtc caaaaaaatc tagcaaacaa gagagaatac cttggatgca 21360 aaaccaaagt acgaaggcaa gtactaagag tttaatgaga acgacgatct ttttccattt 21420 ctaattgctg gtagagtaag aaaagggctt tctcattttc ctcgtgtgta cctgtaatgg 21480 tgaacatacg ttcgcctgtc tcatcatgag gttctttggc aatggaaatc ttgctaccgc 21540 tggtacgacg gatttccgaa atcttagatc ctccacgacc tattatacaa ccaaccatat 21600 ctgcgggaat gctaatattt tgggtaacct taggttgctg caagaaaggc atttgggtag 21660 ctggaaagac ttgagcaccg taagaaacaa agttttcggg gatagcttca ccagaagtcg 21720 tggagggagc tgctggaggg gagacttgtt gaggagatgc agtcgacgca agagaaggaa 21780 gaggttgagt caaacgagaa acgggattat agaaaacggt accggcgcca cgctcccagt 21840 catcaattaa gcatttgcca atttcccaaa tggcagcatg aagattatcg actgtaccat 21900 ggatttcaac tgtacgctca gtagactgtg gaagcatgtc tttggaagca atcatacggc 21960 aactacattt gtcctgaata agcttgatac gcaaaccatt gcggccaata atactaccca 22020 tcagagaatg ggcgatcaaa agacgaagtt tgcgaggtgt gttggcgtcg gaaggtgtac 22080 catcagggtt agtactgttc ttggcaaaaa tatcgatgat gaatctataa gcgcgaacaa 22140 cattctctag tggtccacta atagttaaaa cacgatcatg aacattagga acagccttgg 22200 taacgccggc cttgacattt gtagtgcttc tgagttcggc aacgtttttt ccagctttac 22260 caataatgat accagcttca cgagtagaaa gtaaggctct caaggtaagt tgttgagtag 22320 cataggtggc atcatccatc ggtggcttgg cagagatggg aggcacttga gacgttggtt 22380 cgggttggtt ggtcatggac tgttgaatag tagaaccgtt agtaagagtc gatagaggtg 22440 tagagggctt tggagtaggt atggaaactt tagcaatgcc agtagcagta gaagtggttt 22500 cgtcgggttc gtcttgaaac gttacgtcaa aaaaagagtt ctctttttcc tcgatgtttt 22560 taggaatgct gaagtgattg taagccatag atgtcactgg aatagtattg gttaattgaa 22620 taggacacat atgcgtttct aggaggagag tagaaccttt tctaaattac ttcctgaaaa 22680 ctgattagtt caaacctgca gggatttagc ggagattaaa aaaaaaaagg aaaacggatt 22740 aggctccttc taagctctta ttgcagtttc ttataaattg aaattgcaat caatagctgt 22800 gattacttcg acaaaaatga agtaaacgac caaggagaac ggagtagtgg taaacggggt 22860 gtagcagtga caaagagaaa attttctgca agtaagtctt ttggtgggga aataacgaag 22920 tttgaagaac gtatagtaaa gtcgcacaat ttactgatag gaagtggtag cgtagcttta 22980 cgcctcagtc gttatatctt tggaagtgaa aatgatgaga ttaataaatg agaagagcat 23040 tacaagaatg ggttttttaa ataatcgtaa atttcctagc taaagctaac gaatgctgcc 23100 aagtgaaata tcattctttt agtcaatata gcaggtatta acgtagttgt tttcgttggc 23160 ctttgcttcg gtatatagga tagcgtggtt caagcgactt tgtaagatca gatgaaagat 23220 aaagggcaaa aacctaaata gcgtccatgc atcagtggaa ctttctttct tcagattacg 23280 ttatatggta tagtgagctt tgaaaatcgt tgaaaaaatt cgaatttaat ggtgcagagg 23340 caaagacgat atggacgttc ggaaaaatga aaactatact ggaggaagtt atctttattt 23400 gattctgtct tcgtaattaa gcttccttca gcttcgaact tttcatttcc taattcgaat 23460 acctatttgt tcacccgtac ctctttaggt ttatatttgt tcttgcaaac tgttctgcgg 23520 cgatatgaat tttgctaccc caaagtttac gtaagccaag tttgtcgtaa ataaattcgc 23580 aaaaaaaagt actttggatg gtgcaacatg gaagaattga acgccgttga aacgctggta 23640 tttttgaaca tgaagtatct cagtattcaa cccaaagtca taaaaattct tgaaccttta 23700 gctttccaag cgctgaatga gcatactggg acacattttg aaaccataga cgcaagtaat 23760 aattgcgtaa gttatataaa actcatagag ccaacaaagc tagtagcatt tacttcttaa 23820 tattatattg aaattccaat aaataatctt tgaatatcgt ttgtatgaaa tacccgagag 23880 caattgcggc gctaaattaa actgaatgtt cagttaccaa gatttatgtc acttcataga 23940 aagatataat atcacagtag cgtgtaccat tcttctatac ctcactgaac gaggaagtct 24000 acaattctgc ttggcctagc acagtgttag cgagggtgaa gaataaaatt atgatgctaa 24060 ttaccaaaac ggtgatttca aaaaaagttg aggaactttc atattttcat tttttgcctc 24120 ttataggacg ctatgtatta cgttgcgtaa ctttgacttt tgcaaatact tggatgtacc 24180 actgtctcca tgtttgtttg ttggtcaata taaaacgtag tattagacat taaaatattg 24240 gtttaattat ttcatttaga aaactcaata gaaatttagc aaatatcgtc aaccaaccta 24300 gattgatcct gtttcacgca attcggacta tatgaatcgt ttttgattgc tttctagact 24360 tcatagcatt attacttacc cttctacttt tttaatacct tcgaaattgt caaattgact 24420 cattattgca aaaatgctgt acaggctctc cgaaaaacag cagacagact tacggtgtaa 24480 taaattaact gtcgatggat ttgagctggt aaaaatgtta aaggaattac gattacataa 24540 caggaatatc aattttttgg aatttcttcg aggtgtacag attgtgccga gcgacagtgt 24600 cttcttgggc gaaattgatg aaaacagcca tactcaagac aatacaacta cttctatctt 24660 aaaggagaaa gagctatatg atggtattcc tctgcttcca tcaatggcag gcgtatccat 24720 ggaccctgag agagaaaaaa aatcagagtt acgactaatg aaaaaccaaa tcagcgctat 24780 aatcaatata ctcttcacag tagtaggaac ggtgaccgct gtttggtact gcacttcatc 24840 tttatctatt gaaaaggtat gaattaaaaa ctttcgtttt gttcctggga gacctttgta 24900 ttgacttaat attatttaga aaattgcgct atgtgcgttt tcagcaatct tggttctagt 24960 agcagatacg tttctttatg tccgctatct atctgcacaa cccgtacgaa cttcaaagaa 25020 tcatactcga caaataatat atacatggac aacaaatgac cctgttctac agtcaaatga 25080 gcagctagct atagaactgg gagccattcc atctttgaag gaaaaaaaga accaataatt 25140 atattcttaa tttttagatg ttttattaac gaaagtacct ttgatgtttt cctgtagatg 25200 atttttatag gttgtttgtc taattgatca taatggcata cctctctatg tgttaattga 25260 agggcaggca cctatgggca cactatagat aaaaaataaa aagtatttaa gataaaaaat 25320 tcgaactcat ttggctttta acgtatattt catcaattaa tttcattata attaaagatt 25380 tagcaacatt atttcaattt aattagccat ttggtattag atttatttgt aaggaacaca 25440 acttacaaat ttataaataa acaacaaatc aaccccccct tgtaaaaaaa ttaaaaaaaa 25500 aaaaaaaaat agagagcaac ctaaccattg agttaccagt gaattatgca aggcgcaact 25560 tgaccttaag tttcttccat ataatcaata gtgcaagcac agacataacg tttaatatta 25620 agcataccgc aaaaaaaaca acaggtgaga acgagcgaaa tgcaccgcca aagatagcac 25680 caactgtgtc ggataaggaa attgatattt gcacagcgac gttacctatc aggtggtact 25740 taggatgtaa aacctttgtc aataaagaga ccgaagggga attagcaata gaagatccaa 25800 aaaaaacaag ggtgtaaata ataaagtaag gttgtacgaa ttccttgcct gtatagtgaa 25860 tagttatatg aataaccatg catacgatgt ttaaacaaca acccaacaat atgatatctc 25920 tgtcagtcaa gtaacgcgtc aaataggaaa atattaaaag caagggtacg ttgataattc 25980 cagccaaaga aaggaagtta cctgcttgga aggatgaata attataaagc atagaagtgt 26040 aaattggaac agatgcttgg tatgcattta atagaaagta agcagagaag ccagagaaag 26100 cgacaacgaa aataacaaga caccccacaa atcctagttt tgaattggta tcctgtttga 26160 catcattaat gacatgcttc tcttcgacta cttcttcctt tacgtccgtt tgcgggctca 26220 aaacctcccg gaaacaagca aagccaaaca aaaacaagcc tacccaaatg aaagccatta 26280 gccagttacc cgaagtatat tcattccaga tatcgctttg agacttcatt gaagacttgg 26340 ccattaatcc tccgatgaat ggaccagctg tcaaaccaag cgttgccatg actgagttga 26400 ccacacccat cgacgttcta tatttgatgc tgatcaaggc tttatctgtg aaatagcgct 26460 tgtggtataa aaacatggta cacgcaacac ccgtaaaaat acgactcaca agaatcaagg 26520 ccacactttt ggctttatct gcgagtgcat acatgatatg accaataatg cagcttatac 26580 acgacattgt atatggtctt ctataaatcg tatatccctt ggcagctttc ggagtcgaga 26640 atctcaacat gggatacagc aacacaaggg cagtgattgt gggcaatccg ataattacac 26700 cggacaaacc atttcctccc cccagatgtt ggacaaatct ctcggacgta ggaacgacaa 26760 tggtgaatga aatgcaaaga attgtgttat ttaacagcat caaagccgca ctgatgaacg 26820 gtggtttatg cgtagcagcc ggtgaggcag aagggtcatt ggaaactaat cttacagatt 26880 gcttgtatcc cgacttttcc ttttcatcaa gaaaggatga gaccgagagg tctttttcta 26940 aattactttg ttgctccata atatagactc aatggatcca ttcaaaaacc tgctctacta 27000 cgaaaactgg cctgtggaat aaggtataga aggaacgaga aaacaaagag aaattctttg 27060 ttgttttcaa atattttggt gtgagtaaag gaagaaagtg gaatttcaat agaatagcat 27120 gactcgttta ttttatatga gatcaatttt tttaagttga tgatatccga taattttcat 27180 catcgtatag aatggataag aattcccaaa ataggatatc cacggtgctt ccctaattaa 27240 gctttccgta gtgcggagta ttttaccata tatcagtcat tagttgtacg gctactgtac 27300 tagctcacat ggtccagtgg ttaagactca tcgttgtggc cgatgcgacc caggttcgat 27360 tcctggtgtg ggcagtttat ttatttgttc ttttttaaat tattaattac ttgtataaat 27420 aggaaataat cagcgagagc aaatagtaca attcagttat ggcaagtaca aaaacgcaaa 27480 gataaatgca aacgtagaaa ccggtagaca tgatggtaga aggagaatag aattatgata 27540 ggatatgatg ataagtatcg aatagaaatg tcttgcaaag tgtgtttggc agataagccc 27600 atttgagcgg tcgaatattt tatgcttttt ttcagggcca gccggcaaga tcacctgtct 27660 atttgtccgt tggcagtaag cgtttgctca agatatggat gcgcttcagt acttgaagat 27720 ttacagactg ttcgggacgg aaagactcat gactgttcgg gtcgatcatt ttggctacta 27780 tccgtctgtc tatgataacc agtgtatgca tggaaaaaat gtatcgtaaa tcgtttaatg 27840 agaatagggc ataaagcgtt attcaacgga tgaagaagga aacttgacaa tggcgatgtt 27900 gaaagacaag ctatgtgaga tagcagattg gttccttgca gtacaccagc ccctacaaat 27960 actatgattc ttttaactta aacatcctgc tcagttcctt ctaatcaata cttggttaca 28020 ctagtttttt ggcataatga gttctcaaac atgctttaca atctctctta cattgtacta 28080 tgtatgatga aaatccaagt tttgcatatt tcgcctagtg cacactgccc acaacctttt 28140 ctcttgcaca cgtaggtggc tatgaaagag gatcgtctgt gcgcctcata aatatcgtta 28200 ttcagcatat caagtttttg cagcaatgtt tcatacgacg ctcaaacatc ctacctagat 28260 attgtttttt tgaatttata ggccaaaata gaatagaatg acaatttgct ttgtactcac 28320 caagtccgcg cttgtgatta ctttgtaatc atatatttat ttatttatta ttcttgttct 28380 attgtttatt tactagtgac ctcatcttcc tttcctgaac atcgcaatgt ttcctcatct 28440 cttcttccct ttcccatgtc ctcgttccta aagttaaaat ctttgtttat cgacctatta 28500 ttaataatcg gtaaacaagt ttaacgcttg ttcttacacc tttttatgtg tatttacagc 28560 cgccaaacgt ggcttattca aagccccact tgagaaccaa tgcgagcgca tctggaaaaa 28620 gggctatcgg taacaaacag tctcatctta cgtcagccta aatccgccga agcagcgatc 28680 ggcctcgtgg ttgttaccta gctgccatgg cgatatttgt ttacattcgt gctcgcagtc 28740 atataaataa aagatcctcg ctacactact gaacctctac acatctaaca ttttgcatat 28800 ttttctaata tcctcccttt agtaggctat atctaaaggg tttgataccc gttcttcata 28860 acttttcttt ttctatcttt tttgtttcgt ttttttggtt tcttttgcgt gccaaatttt 28920 tggtcttttt gattttgcat ttcatttcta tttttcttgg tttccccatt ttttggtttt 28980 gtatgagtgt gctcaatcaa cttgtcaaat aatttcctca tcgcatacca tattgattaa 29040 cttttccttt tcttttttta atcgtttttt tttttgcatt tacattccca cttgccaaac 29100 cgagaatata tcgcccggcg tttgattttg tttcccatat tttcctcttc gacacgagcc 29160 tttccttgtt gccttctttt gttttttgtt ttttttgttt gttgagccgt catttctaca 29220 aaacattccc ttttgcattt ttcatcgcat atatagccta aaagttatct ctcaaagtgc 29280 catctatttt ttggtttctt ttttttttca gattattctt ttttaatttg aattctccct 29340 ttctctctct ctatttcaat cacttccaga aaaattagca gaagtatggg gttttctaaa 29400 atagcacttt tttctttatt cgcgctcttc ggccttccta cctctcttgc taaaagcagt 29460 gaggaatggc gcgaccgtat catttaccag gtcataactg acagatttgc cgttgactct 29520 gataatacac ccgattgctc cttcgatgat agttcttatt gcggtggtac atggagcggt 29580 attcgttcta aactcgacta catccaagga atgggattca acgccatctg gatctctcct 29640 gtcgaaaaga atcttgaggg ttcttacggt agtgatggtg aagcttacca tggttattgg 29700 aataccgatt tcactcaatt aaacgagcat tttggttcgg aggatgatct catcgattta 29760 atcactgata tgcacaatcg tgacatgtgg atcatgtttg acgcgttggc caactcaatg 29820 gccattccag gacccaccga taacatcagc tactcgaatc ttgtgccttt taatgactca 29880 tcctacttcc atccttactg ttggattgac tatggcagta acaataatac agatattgag 29940 gattgttgga ctggtgatga caatgtcatc cttgccgatt tagacattga gtccacgaat 30000 gttgctgatt atttgcatga acatattcac gatatggtcg agcgttatca gattgatgga 30060 attcgtatcg atgcagttaa acaaatgaat cccgaatttt tccccaacta cacttctgct 30120 gctggtgttt ttgctattgg cgaaatgttt agttacgatc ccaatgtctc ttgttcagtg 30180 cgtaattatc tcgacagcat taccagctat cccattcgtc aaggaattga atttgcattt 30240 aattatactg gtgctgcatt tgaatatctt caggagattg atacgcaatt ccagcaagct 30300 tgtgagggac aagatatgtc ggttatcgga aactttttgg agaaccatga ccttccccgt 30360 tacacctcta ttaccaatga tacctcacaa gatattggcg ccattgtttt cctccttctg 30420 catactggca ttcccattat ttattatgga gaagaacaac gcttgcctgg tggctctgat 30480 accccggaaa accgtgccgc cttgtggaat tacggctatg acactgatgc aaattattac 30540 caaaccattc gcactgctat tgctctacga aaacaagcta taagtgacag tgattcttgg 30600 accacagatt ctcactctta tttggactac gatctgcgcc atgctgtggt aagaaaaggt 30660 gatgttttgg gagtttacac aaactacgag tcaagttctg acaacgttac ttatgatgtc 30720 tcctctaatt ttgatgatgg tactgttttg cgcgaggttt tgagcaatac tactacgacc 30780 gttggctcaa gtggagcatt gcacgttact gttgtaagcg gtctacctca ggtctattat 30840 cctgaggcta gtttgacttc ctttggaaac ttcctaggaa cggccacaag ttattcttct 30900 gcctcggcga gctatccttc tacttcgatg agtgcttcgc tttcatctgt gcatacatca 30960 tctgccacat caagctccaa gtctagctct agctctagct ccaggtccgg ctctagttca 31020 agttcaagct ccaggtccgg ttcgacttct tctagcggct ctagccatac catcacttct 31080 acttctcaaa gtgtgcacac gagtggatcg tcgacatcta ctagtagtgt agcggtcact 31140 tccacggcat acagtagtag ttctagctcg tcttcctcaa gcagtattga aagttctgct 31200 aatgctgttc gtgtatctat ccttggcgtt gcagcattca ttgctatcgt tctattcatt 31260 tagttaaaaa aataatttta tggaaatcta tcttttgcat ctttaataat ctcaacgcat 31320 gcttaaactt tcgtattcgc tacagtgtta cagtgtctgt ttaagcttgt tgtttttgct 31380 aactataaat cgtttcatca caataaaaca tcatttttgc acacattcaa taaaactagt 31440 gtgtaggtgc gtttacgcgt aatagtctgt aaccgaaggg cataatgtat cgggtatgtt 31500 agttgtaaac atatttcgct tttatgtaag gatactgaga ttctatcata tgcgttcaaa 31560 aaaaatagtg atattacgat tgcttgttgt agcttgcagc taacgcaacc tgtgtcaaaa 31620 aattgactgt acgacaaaaa atatatacct agctttaggt gcacaaatcc tctacttcat 31680 ttcaaataca catattggta aagaaagtgt tagtattagt tgagttatct gttggaaata 31740 tgacatttag agggaaacta tcaaaagacc caaatggagc attcgtttat taaaagctta 31800 attttaggcg aaagaaatta gctataacgt ttgtataagg aaaaaagtat tgtgtatcaa 31860 atcgctagat cgaacatgca ttgtaataac agcatattta acagtgaaat tgaccataaa 31920 tctcaaaaga aggattatat aaattgatct ttagtcttta agagcaaaag cagttaaacg 31980 gttttgtaga acaggtagtg aaacgtcaat aaaaggatcg aattttagat attcaataat 32040 tagatattta aattaggcaa ttctctgttt agtatttgac ggttaacttt acagtacatt 32100 ctagtgaaaa cctaaaggcc accagataac caactaagta aatgtgaatg atacttataa 32160 attttttttt attcgctttt agcacctttt gaatttaaaa cgatccacgt atctcgatag 32220 ctgtgtacta aaatatcaaa gcaaaagtaa acatctttca gtatgatcac tctcaaataa 32280 ttacagatta ttcggtaaaa aaaaaaatta aaaaaataat aatatatata tatttaaaaa 32340 aattcaattt gttttcaagc ttgtacttta catagcaaat actaaaattt cctacaagtg 32400 ccgatatcac atcttaaatt tgttgaatgc tatatttatg tagtacactc ttcaaatttg 32460 taaaaaataa attataacaa tagcatcgat atcaataata aatcgaaaat aatagtaatt 32520 agttgaaacc tcgattaaaa atacgatata gtttgtacac ttgtaaagta cattaaaaat 32580 ttttgaatta aaaacattca cctgtttttc aaaaataaag tctcttgaag gaatttataa 32640 acggactcac aaacacagaa tcaactactg taaagttaat ttgtagatga ataaataaat 32700 gaaaactgcg tatctcaaat ttcaattttc gccaaaaatc gcatgtaatc atgcaaaaca 32760 aacgaatttt ttaagcggga cgaaacgatt aagctataaa aaaagtggca tcttttgtaa 32820 taacgtggac tatgcatagg gtcaatttat caacaagaaa aaaatttttt ttctgtcaaa 32880 ctcaaaccca aacagggtaa ataaccaagt tttcttaaaa atccttaact ccataatctc 32940 tatcgtagcc ctcagaaacc agtatttaca caccctcctg cacaatagcg taagatagta 33000 ataagaaagt atggcaagtc atcttaacga gatgcgatat tattagataa aacactcaat 33060 ctagcaagcg aaatatcgga tctcaactgg tatggtaatt tatcaaggaa tttgggcata 33120 ttgcttaagt aaatttagac gactgtacgt aacaaaccgg ggaatgtacg cgaagtagaa 33180 aagatacgaa aaatgtctga tcacaagatt tttttgttca tcagtagtcc ggacatttcg 33240 atttgcaatg ttaagcgata tccgtttgtg aaaccatgcg aaaatccatt ccaaaaatct 33300 atgcgacgaa cactttgtga gtcatattga ctgttgaaag tagtgtactg ctgcacacaa 33360 tgttcgttgt cattctatgc tagttattga gatatgttgg tcaactttgg cataaaaaaa 33420 ttttcagttc agactaaagg agatatctta actccctatt ataggccata gcactcagga 33480 caagcgatta tattttttta tcagttataa gttaagcgac attgataagt atctaacagt 33540 aaggttagta gagtaaggga attttatgtc agaaaaaaag cacttgattg ctcatagata 33600 tctaaagagg caacagatat ttaaaaaaga aaattttcgg tcaattactt ggtataaatg 33660 aagctcaatt cctttcattt tgaaaccaga ttaggatttg gtgttttcat tgctaatttt 33720 attttatttt tttatttcct tttcatttta cctcgaaatt aggaaaataa gttgtgcttt 33780 gtgagcaaaa gcaagaccaa ttaatcaatc gtttggaaag aatcgctcta taataaaggg 33840 atttgattat ttattgttat cggtttctta aatacttcct cattttcatt atctttttct 33900 accttgattc atcgattccc tctctacttt atacattgtt ttaattatgt cttccatcac 33960 ttcaagggtg tcgtcgcgct cctctcatga gctgacggaa aagaagtctg gtgttaccaa 34020 tgatttcaaa aattctttcg aagtcggcga agtcaagcgc ttgcccgatg cagaaggaac 34080 cgcagatgcg gtggctcagg aactgcttgc tgatgatgat tttacttata ctgcaaagga 34140 agcgaggcgt gtgttgtgga agatcgactt ggtcatgatg ccggttatgt gcatcacata 34200 catgattcaa tatttggaca aaacagcctt gtcttatgcc gctctttatg gtatgaagac 34260 ggacacacac attgacggtc atacgtacag tagtatgact actctctttt atgccggcta 34320 tctcgtcgct caataccccg ctgctatttt aatgcaaaaa tgccgtcttt cttatttcat 34380 cttctgtaat gtctttctct ggagcgctat ggtctgcctt atggcggctt gtcgaaatgg 34440 tccatctctg ctaggccttc gtttcttagc tggtatcttt gaggcttcta ttacccctgc 34500 attcattaac atcacagcaa tgtggtatcg tcgtgaagaa caacccatgc gtactctatg 34560 ttggtatgcg tttaatggaa tagcccaaat cattggatcc attctttctt acggtctcgg 34620 tcacattcat ggaaaggttg cttcatggag atacgttttc atcgttattg gtttaatgtc 34680 cttaggatgg ggtgttgttt ttgtttttat tcctagtaat cccagtaaag cccgttttct 34740 gtcttctcgt gagaagcgta ttgcacttga gcgcgtccgt gacaaccgta ccggtttgga 34800 aaacaagcag ttcaagtgga agcatgctta tgaggcattt ttggatcccc aagtcatcat 34860 gatcaccttg tttactggtg tttgtatgat caccaatggt atcggtgtat tcagcacttt 34920 gattattaaa ggtttgggat ataatgagct tcattcggca gttttgaata tgccacttgg 34980 tgctattgaa gtggctgcta tgttcatttc tggtgtcttg tgcaaggtct ttaaaaatgg 35040 tcgtctttta atcggtgttt ttatgaattg tctcacccta gctggttgcc taatgatatg 35100 gaagattccc gattccaatc cttatggtcg tctggtaggt gtttggttta ccatgtgggt 35160 gcctgcatct agtgctctgc ttttgtcatt gatttcttcc aacgtcgctg gttacacaaa 35220 aaaaactgtt acaagtgcaa ctgttttcgt tttttattca gttggtaaca ttgtgtcgcc 35280 tcagttattt aaatcgggtc aaactcctga gtatatcgaa ggtattcaag caatgattgt 35340 ttccttgtgc ataattattg ctattgcttt tgttctgact ggttactata tttacgaaaa 35400 taaacgccgt gacagacttt tagctgagga tccttctttg ggagagtcaa ttaagaatga 35460 agagtttatg gatctcacag atcgtcaaca acccaaattt cgttatagat ggtaatacag 35520 tttctctcgc aacaaagagg aagtattgtt gtcattttaa tatctcgtta atgaatgatc 35580 cttactctgc ctattgcggt cacacgttcc ccttctcatg tcatgtttga ttatctctta 35640 tatttcttta ttgtttcaac gtttgttctt aatttaagat gtgtatatta taagttaaat 35700 aaagtgaaaa tgatattttt aatactattc aatttagtat aaatacattt tggtgttgta 35760 aacaaattac agtctatgtc tatgtactat tttcattatt gcttcgtctg gtacagtact 35820 taacgtctta tttgatgaaa caaggggttg aatgcaagtg gtacatctgt tcactactct 35880 ttctaataat gtatcaggtg atatagtcgt aaaatgaatc taatcccaaa cttcattcaa 35940 gggcctaaat ccatatacaa cggctgaagc catccagaac gctttttgca aatacatcta 36000 ttgaagtcct agttgagacg gattttggaa cgcagactaa gtaaactcaa cattatgtcg 36060 aacgacaaag atgatcctat ccgttgtata ctttttagtt ccttagcacc atattctcaa 36120 ttaaaaatcc ctacaaaacc tgtgatctaa atacaacagc tattattaat taaatcgtgc 36180 tgtatatagc aacaaacatc ttgaagcaag atattttttt ttccccaaac gttgagtgac 36240 cacgatgatg atatctatta aatctaaaaa attttctgtc accgtataat acggagaaaa 36300 actttataaa tgtaaattta ttacaaaatt ttacaaaaag agaaaattga atattctaaa 36360 aaagatagga ttactggcga aatttagtaa catcaagagc attgaagttg aatcgagtat 36420 ttcgaggaaa agcaaaaata tctgtaaaaa tgagcactac gaccgaaaca gtgacatgga 36480 gtcagtataa acctcaggaa actcaaagac gactttcacg ttcaagcact atcactccta 36540 gtgtatcaga atatcgatct ggtttctcaa aaactgcttt tggaaatatt gaactggagg 36600 aaattcctga taaacaaggc aacattacac gtgctacaag caatctcgaa agcaattcat 36660 atccgaaagc attagatcct gatgcttgtc ctcctaaacg atcaattgca cttgtattac 36720 tcaacaatct catgtctgaa atgtctttga ctattgcgtt gccaatttcg gctgcataca 36780 ctgaaatttt gggaggtact gatgctttct caggtcttgt tattggtatt cctactatga 36840 tttcactagt ttgcttatat ccaatgcttc ggtttgcgaa tccaaagtct gccaatggat 36900 atacgctcta ctttcgacca ctgattgttt cctgcatttc tcaaataata ggccatttac 36960 tgtattcact agcgtaccgt gcacaatggc tgtatttaat tcttatcggt cgtatgtgca 37020 gtggtgttgg ttttaccatg tttctgtatc ataaaactta cttgacagat aaaaactttg 37080 ttggacaaaa tcgatccaca tttttggcta ctctaaacat tttggcccag attttagggt 37140 ccatggcagg tgcctttctg ggtggtatat tagcgaaggc ttctatgcac ttgacagacc 37200 caatttggaa tcaatatact gcaggatc 37228 //