ID SPCC70 standard; DNA; FUN; 27999 BP. XX AC AL023794; XX SV AL023794.2 XX DT 04-JUN-1998 (Rel. 56, Created) DT 03-DEC-1999 (Rel. 61, Last updated, Version 4) XX DE S.pombe chromosome III cosmid c70. XX KW atpase inhibitor; leucine permease transcriptional regulator; KW methyl transferase; Neutral zinc metallopeptidases; KW proline oxidase precursor; proline-rich; ser/thr protein kinase; KW thymidylate kinase; tmp1; transmembrane. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-27999 RA Wood V., Rajandream M.A., Barrell B.G., Seeger K., Harris D.; RT ; RL Submitted (02-JUN-1998) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and XX DR GOA; O74523; O74523. DR GOA; O74524; O74524. DR GOA; O74525; O74525. DR GOA; O74526; O74526. DR GOA; O74527; O74527. DR GOA; O74529; O74529. DR GOA; P36590; P36590. DR GOA; P78797; P78797. DR GOA; Q9USI4; Q9USI4. DR SPTREMBL; O74522; O74522. DR SPTREMBL; O74525; O74525. DR SPTREMBL; O74526; O74526. DR SPTREMBL; O74527; O74527. DR SPTREMBL; O74529; O74529. DR SPTREMBL; O94243; O94243. DR SPTREMBL; Q9USI4; Q9USI4. DR SWISS-PROT; O74523; IATP_SCHPO. DR SWISS-PROT; O74524; PROD_SCHPO. DR SWISS-PROT; O74531; POF7_SCHPO. DR SWISS-PROT; P36590; KTHY_SCHPO. DR SWISS-PROT; P78797; YJ4A_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c70 is overlapped by cosmid SPCC1494, EM:AL023776 at the CC 5' end and by cosmid SPCC1827, EM:AL023777 at the 3' end. XX FH Key Location/Qualifiers FH FT source 1..27999 FT /chromosome="III" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c70" FT /map="IIIR" FT misc_feature 1..1838 FT /note="nominal overlap with cosmid SPCC1494, EM:AL023776 S. FT pombe chromosome 3" FT CDS 302..3196 FT /db_xref="SPTREMBL:O74522" FT /label=SPCC70.01 FT /note="SPCC70.01, len:964" FT /gene="SPCC70.01" FT /product="hypothetical protein" FT /gene="SPCC1494.10" FT /protein_id="CAA19351.1" FT /translation="MADFMDIEPSSHSAKASQYESSAPASSSLGNSHPNESLDYYIYDY FT FVKHNFEEAAQAFLRESKIQIPKSSSSTAFSPSNNNAPSPFPPKNSSLASPSKISESIS FT GDRLYNHMSSAPSPNKKEETNVVHANEDISLDKRQSFGSSSLPPSEVSINVPEGFLVEW FT FNIFWDVFSARVSRVNSTPIQLYDPSTQRQMARPMSNLQASQPVPSSTFSRSAVVPNPS FT LPLNPSVLQGQVMNNPTIPKGTPSTSIEGAKTSIPPSHAMQNPHNSFPASADRLQKNHP FT VQSSNFNPYTPAPSITVPPNYIPNTAMMGPSYSSFGDTDPRTYPAGMGPNPTAARNGFY FT PPTPAQIHQLKAQQQHLQRQSKQMSEPAPINMKSNKDQQLQYVDFRGVGSGADLQKQQW FT NKSTSAEGLQPNGLVMRNFGDVRHQKLPTSSPPSQHPPVGQIPSQYLPYQAGLKVPGNT FT PIPVKQVGGMPLQSPLPVSMKPSADDHSRATPTRSVEAPTLPSYAPRHPTQANGSRYMN FT PSTSRMTPQSPYMQNYYRPHAQMQDQNNMMSYMLSQQKAMEIAKSREMAIQRNTQTLSS FT GNQPPQQSGPNPNEFSMSMDPANMQQGNHALSDYHMQLMLLEEQNKKRLMMARQEQGTG FT SLSPQSYMNSRYSVDVGKEHMSMIPNQTAPMIQPNVPVSANSPAQANTPAADSTKSGTI FT QPTNRNGEGLSYSPHQQFSPSAPQAEKLSRSMSPFVSQQQQLNQPVSNKPDGLTQNKEV FT TGMPLNKEELTNPAFPQSRTSWMMPQSFDTSSLNAPGAKDSSSFSSLHAQPGKSGIATM FT GVADNTIRTTERSTFSEIMKDSPSAHASPGAKTSPNASRAPEPTGGTNSISQDTTQSLQ FT MQSNSVNSSSMVDASKSKEKSGGDTSALDSNAKNEPTAAKPISKLEDDALFNDSAGNAF FT GFSSKTDSNVEMLNDFDFESFLNDAGADSASVYY" FT CDS complement(4300..4572) FT /db_xref="GOA:O74523" FT /db_xref="SWISS-PROT:O74523" FT /label=SPCC70.02c FT /note="SPCC70.02c, len:90, predicted transit peptide 1-19 FT aa, SIMILARITY:Saccharomyces cerevisiae, IATP_YEAST, atpase FT inhibitor, mitochondrial precursor., (85 aa), fasta scores: FT opt: 188, E():1.9e-06, (44.0% identity in 75 aa)" FT /gene="SPCC70.02c" FT /product="putative atpase inhibitor, mitochondrial FT precursor" FT /protein_id="CAA19352.1" FT /translation="MYKYCFRKPACISYRGIRFMSKASDTDPTLANASSAKRSAFESRE FT KAKEDFFVHQHEIEQLRKLKESLKLHREELDELESRVDKKMKSNE" FT CDS complement(5663..7141) FT /db_xref="GOA:O74524" FT /db_xref="SWISS-PROT:O74524" FT /label=SPCC70.03c FT /note="SPCC70.03c, len:492, predicted transit peptide 1-35 FT aa, SIMILARITY:Drosophila melanogaster, PUT1_DROME, proline FT oxidase precursor, (669 aa), fasta scores: opt: 407, FT E():5.3e-19, (26.2% identity in 538 aa)" FT /gene="SPCC70.03c" FT /product="putative proline oxidase precursor" FT /protein_id="CAA19353.1" FT /translation="MRAFRLASGVLRNRKVILGIGAGSLITAGNIKIRNDSKFDAFFAK FT GFPDELQHRSLFSVLRSAFVYEICSRAWLVKLSLGAMSLCDVFHLSFLYNPFCRYTFYK FT HFCGGETPQAVMATMDTLQAAGITSCLNYSREVDLDGDMDVNKIASQGVVPPQVPVPSE FT KNQKVLRQIADKAFESNMHIIDMATYKPGTVCAVKLTPFINPLVLQRYNSILNQYPVES FT ACNYLEHLKSPELSTYEVSELKKFWEYADKLCQFAKEKQIPLFIDAEQTYFQDCMHAVT FT VDLMRKYNKEVAIVHNTYQLYLKKSRKIMDDHIKKCVAEGWLMGAKLVRGAYLNSEPRF FT LIHDTKAETDKDFDSAVEAIIAAAAKFAPGDPASASDPIASRKGKWGIMVASHNKKTMF FT ESVNLAETKKVDFTKTSFYLAQLLGMADDITYALAYSQRNQQPNFCIVKYVSCGPISEV FT LPYLVRRARENIDALDRCKEERAYYRQALRRRIF" FT CDS join(complement(8909..9344),complement(8681..8848), FT complement(8506..8636)) FT /db_xref="GOA:O74525" FT /db_xref="SPTREMBL:O74525" FT /label=SPCC70.04c FT /note="SPCC70.04c, len:244" FT /gene="SPCC70.04c" FT /product="hypothetical transmembrane protein" FT /protein_id="CAA19354.1" FT /translation="MKQNNKKPLPSKTKEISLETDWIDVIETMRETNESPKSQNPSEEA FT TTVNELSCEAKPKLLFTPTKSSLSIGNFPYKEFDPVLKFPGIHYTYSRERLWGTCVILS FT TLFWSYYVLSNSELLEFEASEYSLLFILIIALDALLTVSLFGLFHHLMFLTTNYSYTIN FT STLDISKGFFINVLSTMVQALVTVTIAFTKFVTIDFPIYVFSSLFLYHPLSRSRQLPTK FT MQLDGSGERKTDSSLVHQNPPN" FT misc_feature complement(8637..8652) FT /note="ctaaccgtacttttag, splice branch and acceptor" FT misc_feature complement(8675..8680) FT /note="gtacgt, splice donor sequence" FT misc_feature complement(8849..8863) FT /note="ctaatgaatgaatag, splice branch and acceptor" FT misc_feature complement(8903..8908) FT /note="gtaagc, splice donor sequence" FT misc_feature complement(9345..14012) FT /note="low-complexity gene-free region" FT CDS complement(14013..16358) FT /db_xref="GOA:O74526" FT /db_xref="SPTREMBL:O74526" FT /label=SPCC70.05c FT /note="SPCC70.05c, len:781, SIMILARITY:Schizosaccharomyces FT pombe, O94647, protein kinase., (461 aa), fasta scores: FT opt: 654, E():1.5e-23, (29.9% identity in 431 aa)" FT /gene="SPCC70.05c" FT /product="ser/thr protein kinase" FT /protein_id="CAA19355.1" FT /translation="MPSDKPVFDIGSQAPERSDSESPSSRSIGSGTPAPVRKGLSKFKN FT SFLSRKNSSQIKSPSDYKSSAHEQRVNHTTDSMAHVPGNNSPLQTPQKSPPRQKHTAPA FT TPIPVSASRHHKPHHSGLKNLLEKAMHPGHKSNANSPTSESPSKGFGSFINNHILHKNT FT SSHPSSPVNGKSSDIHKSQSYQHLKNSPPNSRTARKPVPRRANSASHNLGSTKSPNGNA FT KESLSRSAELPSKAKPMEINNGYRKKPSPLSPNSSIRNREGGNGSYFDGPLTASPTPSS FT PTGTPNSMSKSPSLSSLASTGASYRPGPSKPLVSRVRDNYANTSYESWPHSTEFDMFTY FT AVSGSLKLTPQGTGFDCINPANPFSPGYSGKSSMKSDDNVGSSANTAPNSPTSANSSEG FT NQGNGPTTYPIKPPTNISEIPRKLKSGFIPPYAKRVVPRLSAKYKLVDETKDMGSGATA FT VIRIVTLKNPKENEKNLRFAVKAYRRKADDETDGQYIAKLASEWLVQCRMEHPNVVKSY FT DLCIDSHIFPLYSDTWCAVMDFCPRGDLLSLIEDRHDRLGKKDFECMIKQILRGLNYIH FT SQGIAHRDIKPENILISEYGVLRITDFGACDVLCNPGDDITAVESKSMGIFGSDPYMAP FT EILTPGSYNAFFADMWSTAIVLHCLYFRTYPFRKASQNDQLYAKYCKAWREYNLICDVQ FT NIRISKTLPYFKPVNDLPMHMQRLFFCLANPTAEQRITAQEALNLPFVQEIECCSVDDC FT TCTHDAPEECLEWANPPVQKLSTPHNHL" FT misc_feature complement(14133..15023) FT /note="Pfam match to entry pkinase PF00069, Eukaryotic prot FT ein kinase domain" FT misc_feature complement(14583..14621) FT /note="PS00108 Serine/Threonine protein kinases active-site FT signature" FT misc_feature complement(16359..19831) FT CDS join(19832..20483,20520..21106) FT /db_xref="GOA:O74527" FT /db_xref="SPTREMBL:O74527" FT /label=SPCC70.06 FT /note="SPCC70.06, len:412, SIMILARITY:Schizosaccharomyces FT pombe, O74889, putative leucine permease transcriptional FT regulator., (1024 aa), fasta scores: opt: 706, E():0, FT (41.4% identity in 374 aa)" FT /gene="SPCC70.06" FT /product="putative leucine permease transcriptional FT regulator" FT /protein_id="CAA19356.1" FT /translation="MSTKVKQKQKQKHRPKPSLDRSDSTKRAARAARFSTTLDANFQAL FT KKKRKDEQESFQAKQSTNWEKSSVLVGTCRQMCPEFELEERKLQHAIHPYELDPVSKQA FT HPSLAVKAYHRPAAGKGPILPSDVRPPSILKNTIDYLFKVILDRYSLREAHAFVRDRTR FT AVRQDFSVQSSFSQDSVYCHELIARFHIISLHELAHTPNFSRQQEIEQLSKSMEILYTL FT GQLYDYMHLRKEHCTHEAEFRAYMVLLSLGDPSVGLDTLSWPDFVFKKPIVKTSLKLYS FT LAQRNNHTITTSNSISLSLVSSFNTEATSNLYTRFFKIASSFRVSYLMGCLLDLFVPSI FT RTGALKAMKKCYLSAHSNIPFKDLMKILAATSEDELVQCCKMHGLKIEYIGEQPSAVVL FT NRKTVITGMIVVS" FT CDS join(19832..20483,20520..21086,21130..21287) FT /db_xref="GOA:Q9USI4" FT /db_xref="SPTREMBL:Q9USI4" FT /label=SPCC70.06 FT /note="SPCC70.06, len:458, SIMILARITY:Schizosaccharomyces FT pombe, O74889, putative leucine permease transcriptional FT regulator., (1024 aa), fasta scores: opt: 706, E():0, FT (38.9% identity in 422 aa)" FT /gene="SPCC70.06" FT /product="similar to N-term of leucine permease FT transcriptional regulator" FT /protein_id="CAB62160.1" FT /translation="MSTKVKQKQKQKHRPKPSLDRSDSTKRAARAARFSTTLDANFQAL FT KKKRKDEQESFQAKQSTNWEKSSVLVGTCRQMCPEFELEERKLQHAIHPYELDPVSKQA FT HPSLAVKAYHRPAAGKGPILPSDVRPPSILKNTIDYLFKVILDRYSLREAHAFVRDRTR FT AVRQDFSVQSSFSQDSVYCHELIARFHIISLHELAHTPNFSRQQEIEQLSKSMEILYTL FT GQLYDYMHLRKEHCTHEAEFRAYMVLLSLGDPSVGLDTLSWPDFVFKKPIVKTSLKLYS FT LAQRNNHTITTSNSISLSLVSSFNTEATSNLYTRFFKIASSFRVSYLMGCLLDLFVPSI FT RTGALKAMKKCYLSAHSNIPFKDLMKILAATSEDELVQCCKMHGLKIEYIGEQPSAVVL FT NRKTVITEPLLSSEISCRFADEKKPGTNVSDLICLDTDGSSLHRKKPKLFKKRSIVRQR FT " FT misc_feature 20405..20434 FT /note="PS00142 Neutral zinc metallopeptidases, zinc-binding FT region signature" FT misc_feature 20484..20489 FT /note="gtaatt, splice donor sequence" FT misc_feature 20509..20519 FT /note="ctaaccattag, splice branch and acceptor" FT CDS join(complement(22144..22276),complement(21894..22090), FT complement(21499..21801)) FT /db_xref="GOA:P36590" FT /db_xref="SWISS-PROT:P36590" FT /label=tmp1 FT /note="SPCC70.07c, len:210" FT /gene="SPCC70.07c" FT /product="thymidylate kinase" FT /gene="tmp1" FT /protein_id="CAA19357.1" FT /translation="MSKQNRGRLIVIEGLDRSGKSTQCQLLVDKLISQHEKAELFKFPD FT RTTAIGKKIDDYLKESVQLNDQVIHLLFSANRWETIQYIYEQINKGVTCILDRYAFSGI FT AFSAAKGLDWEWCKSPDRGLPRPDLVIFLNVDPRIAATRGQYGEERYEKIEMQEKVLKN FT FQRLQKEFREEGLEFITLDASSSLEDVHSQIVDLVSNVNIHETLDVL" FT misc_feature complement(21802..21815) FT /note="ctaacattaagtag, splice branch and acceptor" FT intron complement(21802..21893) FT /note="confirmed intron" FT misc_feature complement(21888..21893) FT /note="gtatat, splice donor sequence" FT misc_feature complement(21903..21941) FT /note="PS01331 Thymidylate kinase signature" FT misc_feature complement(22091..22115) FT /note="ctaacttgttacgtttactcgatag, splice branch and accepto FT r" FT intron complement(22091..22143) FT /note="confirmed intron" FT misc_feature complement(22138..22143) FT /note="gtaaga, splice donor sequence" FT misc_feature complement(22214..22237) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT intron complement(22303..22361) FT /note="confirmed intron" FT CDS join(complement(23555..23571),complement(22739..23504)) FT /db_xref="GOA:O74529" FT /db_xref="SPTREMBL:O74529" FT /label=SPCC70.08c FT /note="SPCC70.08c, len:260, SIMILARITY:Mycobacterium FT tuberculosis., TAM_MYCTU, probable trans-aconitate FT methyltransferase, (261 aa), fasta scores: opt: 211, FT E():1e-06, (28.1% identity in 270 aa)" FT /gene="SPCC70.08c" FT /product="probable methyltransferase" FT /protein_id="CAA19358.1" FT /translation="MPEDYWSAKDYQRNASFVPKLTKDIVKRINLSSSDELLDLGCGDG FT VLTNELVSQCRRVVGIDASPDMIKAARELGLNAYVIPGEKLLDASEIPSESFDVVFSNA FT ALHWIMRQPKNRPIVMKGVSRVLRTKGRFVAECGAFGNVSEVVGSIYSILLALGATKEQ FT IDQANPWFFGSEDDYTRMLEEAGFHVEYVENISRPTLLNKDVREWLDTFAQHFYHAFPQ FT WKDIIRETVYNALLVTDCRSDGKWFLQYRRLRFVAHKE" FT misc_feature complement(23345..23467) FT /note="Match to PF00398 RrnaAD, Ribosomal RNA adenine FT dimethylases Score 34.84" FT misc_feature complement(23505..23525) FT /note="ttaacgccagaattgaattag, splice branch and acceptor" FT misc_feature complement(23549..23554) FT /note="gtaagc, splice donor sequence" FT CDS join(complement(24584..24725),complement(24043..24527)) FT /db_xref="SPTREMBL:O94243" FT /label=SPCC70.09c FT /note="SPCC70.09c, len:208, SIMILARITY:Schizosaccharomyces FT pombe, O60153, hypothetical 14.7 kd protein., (124 aa), FT fasta scores: opt: 214, E():7.4e-07, (57.6% identity in 59 FT aa)" FT /gene="SPCC70.09c" FT /product="hypothetical protein" FT /protein_id="CAA19359.1" FT /translation="MRKQAGGPCEKLNFPLVELEPYARVNRETTKLNKAHVRRDYSGRS FT ICQPDTNNPTRWKYERPLETIRAWQDVAEGKVPASNEKAARVSNLKTVPSLKRENKEVN FT ANSKPPVKQQEVIESTVISKSQSPSVKQLKLTESTLLAPSSSLKPSVSLKKDISSNLLC FT AAASNGYFRRPAAMRAQTLVPITQPDSKKNELKQKFKHLVHHVLT" FT misc_feature complement(24528..24543) FT /note="ctaacatcctttccag, splice branch and acceptor" FT misc_feature complement(24578..24583) FT /note="gtaagt, splice donor sequence" FT mRNA 25767..26851 FT /note="mRNA from SPD146; putative mRNA for SPCC70.10" FT CDS 25828..26295 FT /db_xref="GOA:P78797" FT /db_xref="SWISS-PROT:P78797" FT /label=SPCC70.10 FT /note="SPCC70.10, len:155, SIMILARITY:Arabidopsis thaliana, FT AAD49970, f24j5.4., (222 aa), fasta scores: opt: 165, FT E():0.056, (31.6% identity in 114 aa)" FT /gene="SPCC70.10" FT /product="hypothetical proline-rich protein" FT /protein_id="CAA19360.1" FT /translation="MFFIVAAGFVIAALIAAIGMAINRFFVRRRQARAGQTKPATTRPM FT AEARARPGATAVPRRSPTSPQSAYVPATVYTSPIGSPRRGSVRYTHVMAHPNTTTTVSE FT NLPEEVPPPYSPAATASNTPQNEASPAATEAVNHERPASPPPVYRPPEEMV" FT CDS complement(26929..27999) FT /codon_start=1 FT /db_xref="SWISS-PROT:O74531" FT /label=SPCC70.11c FT /note="SPCC70.11c, len:356, SIMILARITY:Saccharomyces FT cerevisiae, Q12347, chromosome xii reading frame orf FT ylr097c., (344 aa), fasta scores: opt: 378, E():4.8e-17, FT (28.5% identity in 355 aa)" FT /partial FT /gene="SPCC70.11c" FT /product="hypothetical protein" FT /gene="SPCC1827.08c" FT /protein_id="CAA19361.1" FT /translation="DQLSLELETVNKDILLKKALLHYKDAIKSEREGNLGESLNKYRLA FT HKVHEDVESIYRRLERLQLCKRNEEEEMLNSDASEAMLTVSSVPSPTLTENESVNESVV FT PNILKLPDEVLLVILENCIRDLHDLRYLSSIALTCKHFAKALRADSLYRSFCYCSCEQK FT EWQQSIKSIEEELVEKYQQSWKTLFLKKPRSRFDGCYISVCRYFRPGTSDTSWNQPIHL FT ITYYRYLRLYPNSTCIVYQSSNEPNDVVRNFSVQNTSLFSPMSSSPMFSNGNVALTGSW FT SMTPSGEMLIVYPASQTYTYVQKLQVRGIRLKWISFYSIHNYTSFTNEMPLTHNRDYVF FT SRVYSYTADSESLKRG" FT misc_feature complement(27259..27288) FT /note="PS00659 Glycosyl hydrolases family 5 signature" FT misc_feature 27865..27999 FT /note="nominal overlap with cosmid SPCC1827, EM:AL023777 S. FT pombe chromosome 3" XX SQ Sequence 27999 BP; 9058 A; 5067 C; 5252 G; 8622 T; 0 other; cttttcctca aaaaatatct ggtcttattt cctataatta tttttatatc aatccttacc 60 tgcggttttt cattgcactt ttcctctttg gtttttcttt ttttttggtg ttatacgctg 120 ttaattcatc tttgttttct taaatctctt agctttttgt tttaaatctt tgcactttcc 180 tttacatctt tatagtgttc cacattcgtt tcgttctcca tattcccagt ttgctttttc 240 gatttcatat cgccatttta gataaaattg atgacattta tttagcgtca agaaaaatac 300 aatggctgat ttcatggaca tagagccatc ctctcattct gcaaaagctt ctcaatacga 360 atcctcggct cctgcgtctt cttcactggg taattcgcat ccaaacgagt ctctggatta 420 ttatatatac gactattttg ttaagcacaa ctttgaggaa gccgcacagg cttttttacg 480 agagtcaaaa attcaaattc caaaatcttc ttcatctact gccttttcac cttccaacaa 540 taacgcacct tcacctttcc ccccaaagaa ttcatcttta gcctctccta gcaaaatttc 600 tgaatcgatt tctggtgatc gactttacaa ccacatgtca tcagctccgt ctcccaacaa 660 aaaggaagaa accaatgtcg tacatgctaa cgaggacatt tcattagata aacgccagtc 720 atttggatca tcatcccttc ccccttctga agtttctata aatgttcccg aaggtttctt 780 ggtggagtgg tttaatattt tttgggatgt atttagtgcg cgagtaagtc gtgtaaatag 840 cacgcctatt caattatatg atccttctac tcaaagacaa atggcccgtc ccatgtctaa 900 cctccaagca tctcaacctg ttccttcctc cactttttct cgttccgctg ttgtccccaa 960 tccttctctt cctttaaatc cttctgtttt acagggacaa gtgatgaata acccaaccat 1020 accaaagggc actccttcta catccattga aggtgcaaag acttctatcc caccttctca 1080 tgctatgcaa aatccgcata actctttccc tgcatcagca gatagacttc aaaagaacca 1140 ccctgttcaa tcttccaact ttaacccgta cacacctgca ccttcgatta ctgtcccacc 1200 taattatata ccgaacactg caatgatggg cccttcttat tcttcttttg gtgatactga 1260 tcctcgtact tatcctgcag gaatgggacc aaaccctact gctgctagaa acggctttta 1320 tcctccaact ccggcccaga tacatcaatt aaaggctcaa caacagcatc tccaacgaca 1380 aagcaaacaa atgtcggagc ctgctcctat taacatgaaa tcgaacaaag atcaacaatt 1440 gcagtacgtg gattttcgag gtgttggtag tggcgccgat cttcaaaaac agcaatggaa 1500 caaatctact tctgctgaag gtctccagcc aaatggattg gttatgagga atttcgggga 1560 cgttcgccat caaaagcttc ctacctcttc acctccttcg caacatccac ctgtagggca 1620 gattccatca cagtaccttc cttatcaggc tgggctcaaa gtgccaggta atacacctat 1680 acccgttaaa caagtaggtg gtatgccttt acaatcacca ttacctgtaa gtatgaagcc 1740 ttccgcagat gaccattcac gcgctactcc aacacgttct gttgaagctc ccactttgcc 1800 gtcatacgct cctcggcatc ctactcaagc aaatggatcg aggtatatga acccttctac 1860 ttctcggatg acacctcaat caccttatat gcagaattac taccgtcctc atgctcaaat 1920 gcaggatcaa aacaacatga tgtcctacat gttaagccag cagaaagcta tggagattgc 1980 caaatctaga gaaatggcta tacagcgtaa tactcaaaca cttagctctg gtaatcagcc 2040 acctcaacaa tcaggaccta atccgaatga attttcaatg tcaatggatc cagctaatat 2100 gcagcaaggt aatcatgctc ttagcgacta tcatatgcaa cttatgcttt tggaggaaca 2160 aaacaagaag cgtttgatga tggcacgaca agaacaagga actggttcac tatctccaca 2220 gtcctatatg aatagtcgct atagtgtgga tgtaggtaag gagcatatgt caatgatacc 2280 taatcaaact gctcctatga ttcagccaaa cgtaccggtt agcgcaaatt ccccagcaca 2340 ggccaatact ccagctgctg attcaactaa atccgggact atccaaccga caaatcgaaa 2400 tggcgagggc ttatcatatt cgccacatca acagttctca ccttctgctc cacaagcaga 2460 aaagttaagt cgctcaatgt caccttttgt ttctcagcaa caacagctca atcagcctgt 2520 atctaataaa ccagatggac taactcaaaa taaagaagtg accggaatgc cattgaataa 2580 ggaagaattg acaaatcctg catttccaca aagtagaaca tcttggatga tgccgcagtc 2640 atttgatact agctcattga atgcacctgg tgcgaaggat tcttcttcgt tttcttcctt 2700 acatgcgcaa ccaggaaaaa gtggaatagc tacaatgggt gtcgccgaca atactatacg 2760 cacaaccgaa cgatcgactt tctctgagat aatgaaagat tctccctctg cacatgcttc 2820 tccaggggca aaaacaagcc ctaatgcatc tagagctcca gaaccgacag gaggaactaa 2880 ttccatttca caagatacta ctcagtctct acaaatgcaa tctaacagcg ttaattcatc 2940 gtctatggtg gatgcctcta aaagcaaaga gaaaagtggc ggcgatacat ccgctttgga 3000 ttcaaatgcg aagaatgaac ctacggcggc aaagccaatt tctaaactcg aagatgatgc 3060 tttgtttaac gatagtgctg gaaatgcatt cggcttttct tctaaaaccg acagtaatgt 3120 tgaaatgtta aatgattttg actttgaaag tttcctaaat gatgctggtg cagattcggc 3180 atctgtttat tattaggtgc cgatttcctt tcctactttt cttcaacgct acctgtggag 3240 acgttgtttg tgtaaattag cttggatgga tgaatatttc ttctttattt gtgtctgttt 3300 aaatttgcat ggattgctac aattaccggt ttttttttta taattctcat cattaatcgt 3360 gccatccagc ccgataggtg tattttacat gaagcttttc ctgccaatct actacaccca 3420 tcgaattttt accatattgt tgattttcgt tatttataag ataatgtgta aataaataag 3480 aactgctttc aagcgtatat aataaatatg attcatcatt atactagcag gaatttttat 3540 ctacgtgttc tgaagaaata gttattactt aattaagtag caccattgca taagctaaaa 3600 cattttggaa ctaacgattt ctgtaaacaa tgtttgaata ccaaaggagt tagcataaca 3660 atactgcttg catgatatga tttcacggtc agtaaaagca atccaacatt aatcaattac 3720 acaacctttt tttctggata atgatttgca gggtgaagat gaaataagca ggactatgaa 3780 acaaaagaaa atcgcgaggg gttttaatat tgatcattgg cagtatcgca atttacagca 3840 gggagagaca gctggaattt aaggaaatat gctgattgcc taagtttaat taattaaact 3900 acaacatgcg aaattgaaaa attaagcatc aatccgaaca aactttcaga tcttacagaa 3960 atatgcgttt tttaacacat tgtttataaa catattttaa tgaggcctta aaaaatagca 4020 ttcaatttta ttaactatga taagtaatcg gaaccgatag ataatcgaaa aaagcagggt 4080 tcgcagaaag actcggctat ttgaagagaa gggagttgta aagggggtgg catatccaaa 4140 agccgtaatg atatcttttg ttataacaga aacagctgct tattgcacaa tgcacttatt 4200 atggtaagca gccacataaa aaatcattgt ttcgctatat tgccaacaat cattacgctt 4260 gaggtcgatt tcatgaaaga acatgcttaa gcattagagt tattcattac tcttcatttt 4320 cttatcaacg cgggattcca attcatcaag ttcttcacga tgaagtttga ggctttcctt 4380 caattttcga agttgctcaa tttcatgttg atgaacaaaa aaatcctctt tagccttttc 4440 acgggattca aatgcgcttc gcttggctga agaggcgttt gccaatgttg gatcggtatc 4500 gctagccttc gacatgaaac gaataccacg atatgaaatg caagctggtt tcctgaaaca 4560 atacttgtac atctttttta tgataaaaga gaaggaaatt tccaaataaa gatttgctcg 4620 atcctactaa tggagtggga gatgggagaa agtgagtgac ggaaactggg tgtgtcgagt 4680 agatgaatta cgtttagtcg ccgaaactca attgtaggcg actttctacg caccatccac 4740 cacatttgat tttcattgat ttcaaagaca tttgtttttt gtaccctcag aattttgagg 4800 ttatcacgca attagtaaat taataagatg atactatcta tgcttggaac cgagagcaat 4860 aacgccgaac tttgagcctt tatatttatg tagctattta cagcaaaatg ctggaataaa 4920 tgatggtttt ttatcgtttc taaaaatttg aaggcgtttt aaagaaaata gtttaattat 4980 caattcaagt agtccataat taggactttt ctaaatgtaa gtttcgagta atctactcct 5040 taataagaaa gtatgaataa aaaagtttag gtctataaat tcggaaagat aactgttatt 5100 ttagaagagc cttattgtgt atattgtcat tttgagaaat atataaattt tgacagttaa 5160 atactaagcg ctgattcagc tgatttcaat gtcttagttc cttgacaata gtaaaacaat 5220 tgatatatga caggtttgac tttttaaaca gattggggca cttacttggt acttggaaag 5280 taaacattat atgatttcgc cgcaaattac tagtttgaaa tttcatgaaa ggaatatatt 5340 aacgatggta tgagaaaact catataagcg tagacaacgt ccttaaatat tgaatgtatg 5400 aataaaggag ataaagtacg gcctttgaat tgggtattta ttacattata gacttaaccg 5460 tgactatatg aagataacga aggaaggttg acgtgaaaaa aaacgagcga cgatattctc 5520 ttcacaaatc atatgtacca ataatgagta taatttaaca atgttacagc agacttgaag 5580 cttcgtatag tgaatcgaat aaaacgcctt ttgctttctt tcaattataa gtaccaaacc 5640 ccggtcaagg gagcggagaa cattaaaata tacgacgacg aagagcttgt cggtagtagg 5700 ctcgttcctc tttacatcta tcaagagcat caatattctc acgtgccctg cgtactaagt 5760 aaggaaggac ttcactgata ggtccacaag aaacatattt tacaatgcaa aaattgggct 5820 gttgattgcg ctgagaataa gccaaagcat aggtaatatc atcagccata cccaacaatt 5880 gagccaaata gaaagaggtt ttcgtaaagt caactttttt ggtttctgcc aaattcaccg 5940 attcaaacat tgttttctta ttgtgactag caaccataat tccccatttt cctttacgag 6000 aggcaatcgg gtcagaagca gaggcagggt cacctggagc aaatttggca gctgcggcaa 6060 ttatagcttc cacagctgaa tcaaaatctt tgtctgtctc ggcttttgtg tcgtgaatta 6120 agaatcttgg ttccgagttc aaataagcac cacgaacgag ttttgcgccc attagccagc 6180 cctcagcaac acatttcttg atgtggtcgt ccataatttt tctagatttc ttcaaataca 6240 actgataagt attatgaacg attgcaacct ccttattgta ttttctcatt aagtcaactg 6300 tgacggcatg catgcaatct tggaaataag tttgctcagc atcaataaag agtgggattt 6360 gtttctcttt tgcaaattga cacagtttgt cggcatactc ccaaaatttc tttaattcgc 6420 taacttcata agttgataat tcaggagact tcagatgctc caaatagtta cacgctgatt 6480 ctaccggata ctggttcaaa atggagttgt atcgttgtaa aaccagagga ttaatgaatg 6540 gggtaagctt aacagcgcaa acagttccag gcttataggt tgccatatca atgatgtgca 6600 tgtttgattc aaaagccttg tccgcaattt gtcgtaacac tttctggttc ttctcagaag 6660 gaacaggaac ctgaggaggt actacccctt gagaagcgat cttatttaca tccatatcgc 6720 cgtccaagtc aacttcacga gagtaattca aacaagaggt aatacctgct gcttgcaacg 6780 tatccatcgt agccatgaca gcctgaggcg tctcgccacc acagaaatgt ttgtaaaatg 6840 tatagcggca aaacggattg tataaaaatg atagatggaa gacgtcgcat aaactcatcg 6900 cacctagcga tagcttcact agccaagctc gagaacaaat ttcatagaca aaggcactac 6960 ggaggacgct gaagagagaa cggtgctgca attcatcagg aaatcctttg gcaaaaaacg 7020 catcgaattt gctgtcattg cgaatcttaa tattgccagc tgttattaac gaaccagcac 7080 caatacctaa aatgactttt cgatttctca aaacaccgga agcaaggcga aaggcacgca 7140 tattgacaaa atgaaaataa acacactttg ttgataactt tagtaagtcg tatattagaa 7200 ttcgcaatag gaattggttt agataaaagg ggggggggtt tgttagatta ggtcaaatta 7260 aaaactagat tgaaacactt ttgaaaagcc cgacaagaga cactgacgat tcgctgtggc 7320 taattttatc actttcttga aatcgtaact tttgcacaca cgctcaagaa attaaaatga 7380 aagagaaagc aaataattgt ttttatgatt caatgactat tttgacttca agaagcagta 7440 aaattacaat gacttaatta aagtggaggc tagcgattct tgttcaacca ctcagcagtt 7500 gcaatacaca gttgcttata aatgcgcaat ttcaacttta aatatcaaat tcgttccatg 7560 tgactgtccc cccatagcgt atcatttcga taatctgctt ccatccctat agatataact 7620 atgcctcaaa gtatgaacgc tgtgctatca aagaaggtaa attgataaag cacggaccat 7680 gagtgacaaa aaggtgctgc gcacccaaga taacgggagc taactcccaa agtcgcttaa 7740 agtcaatact gtaggataga tttgtgagat aaaccagcaa aggtatctac tttttattgc 7800 cggttccgat ttaagtgcga tggatttggg taccatgtgt ttggagaggt tttgaacagg 7860 tttgatgttg aaggtttcaa aacgtttgaa ctttgtttaa ggaattggat catgctgtag 7920 cagtagactt ggttgaaagt aaaaacatgt taaaagacta gttagtttta aaaagcaaaa 7980 atcagttatg tcatttctat gaaattgtcg tctcaggttg aaaacgataa aagtagttgt 8040 gcatgcataa aaaaagacaa tgcaagccgc cttgaaaaag gtatacccac ttgaaattca 8100 aagcaagagt tagtagttgt acatacgttt acaagttcgg atggaaatgc gaaacaatca 8160 tccgcggaat aacggaactc ataaacaaga cgagaaagtc gtaagcaaag caaatacagc 8220 gctaaaagct gtcataatgc tgtccatgag gaaaaaatta aattaaagaa aacagaaaaa 8280 gagataagta aaaaggacat cggaaacatt taattccagt cagttaaaca caattacatt 8340 ggtatttcag tcatgtccaa tatttgtaaa tcaaatgaca tgaattactc gagattccct 8400 caacagtcta agaaaaaata tggatgcaca tgatgcatgc atgtaatagc cgtgcaccct 8460 ttaatgctat attaaacaga acctcaataa catgatgata attagctaat tcggaggatt 8520 ttgatgcact aacgaagaat cggtttttcg ttcacccgat ccgtccaact gcattttagt 8580 tggaagttgg cgtgagcgag atagtggatg atataagaac agagaagaga aaacgtctaa 8640 aagtacggtt agaaattcac ttatgtctta ggaaacgtac aaattgggaa gtcaatggta 8700 acaaacttag tgaaagcaat tgttaccgtc acaagtgctt gaaccatagt gctcaaaaca 8760 ttgatgaaga agcccttaga aatatctagc gtagaattaa tggtatatga atagttggtt 8820 gtcaggaaca ttaaatgatg aaataaacct attcattcat tagagactag aaatgataac 8880 gtggacaaag tccagtgtta tagcttacca aacaaagaaa ctgtaagcaa tgcgtccaat 8940 gctataatca aaataaaaag tagggaatat tctgaagctt cgaattcaag taattcagaa 9000 tttgaaagta catagtatga ccagaataac gttgataaga taacacaagt gccccatagt 9060 cgttcacgac tgtaagtata gtgaatacca ggaaatttaa gtactggatc aaattctttg 9120 taaggaaaat taccaattga tagggaggac tttgtaggag tgaacaagag cttgggtttg 9180 gcttcacaag atagttcgtt tacagtagtt gcttcttcag aaggattttg agatttaggt 9240 gactcatttg tctctctcat cgtttcaatt acatctatcc aatctgtttc aagcgaaatt 9300 tctttggttt ttgatggtaa tggctttttg ttattttgtt tcatatttta gtgataagga 9360 tcaacagtaa aagagactta agaaacagtt cacgatagaa tgagcaattg gggaaattaa 9420 ttagattttt tagtgaattg gaaatttatt caatgattac taatttggta aactgacaaa 9480 tggacatgaa tcggcttttt gttctgaaaa caaagggttc acaacctaag ttgggtgcgg 9540 taaataatat aacgaataac tgtattattc cctaatgact gatggcagaa gttgtctacc 9600 ctttattttt gtatattgtg tgaatggaca ggataaaaat aatgaatatt ttgatgcgcc 9660 ataagaattt tggtacatga tatttactag taaggaaaga tgtggatctt ttatatcatg 9720 ttcgtgcaca atactaaatc gttgaatcac agtgttaggc aacacaagtt gtatctcgac 9780 ttgggaatca attcattgct actgttatcg aagattgttc tcatggccac taatccatta 9840 cgttctctac ctttgcgata caacgtatat agacctaaga aaacaagggc atttacaatt 9900 tcatgcattg tgaaaagatg tattcttaat tactaaatca aatgaaaagc agagtatgac 9960 cgcggattaa attgctggtg aagaatacta aagccattta aacgcatcca gagaaaataa 10020 acagaaaaac gcttgtctta atctttgcat gttccgttat cagctttgca aataaaaaat 10080 ataaacaaac ccacgaaacg atacaataac aataatgtgt acatcctcat atcccataac 10140 aatgtttaag catcattatg ttaggtgata ataatgtaca agcacttata ttaagaatag 10200 ggaaaagaag aaataaataa acgaaccgta acgtaacgaa aagaaaaaga ccaattatcg 10260 acattgccaa accattaaaa ccatacatac attcataact cataacaacg aattgaacca 10320 cgtgcacatt attcctgctt ggaagaaagc gcgtcctgtg caatattgat acaaggactt 10380 ctttgaaaaa gagaagcaaa ggaaagaaag atgtgcaatt aatacagcgt tgaatacttg 10440 taatctgggt accttaccca taaaccgatt ctaagtagac tacgcatgta gttttgtgta 10500 agcactgaac cgtggtgtag ggaaatcggc ggaagtcatt gatttgcgat ggaaatgagc 10560 tagatgttct gagacgagaa attgatattc ggaggataca gagatattag atgtggtttg 10620 agtgtccaac ttggtgaaat ccaaaagatg gcattcagaa gagcagtaca aactgccatc 10680 ctgagtggtg gctccacaca ctgtgcaaaa atccaaatcc atcgagtgag taaactaaca 10740 aggaaaagag aacgaaaggc gtggttcgat aacttattga gttaacgtta caagtaagtc 10800 tgtattgatt ttctacgcaa tacgacacag tataggagga tataaaaatg cggcagagga 10860 taatttaaaa agaagaaaaa gagcctagtc cgcaaaatga aagaatcaag agaaagcgaa 10920 atgaaacaaa tagaaataaa tagaatcact atttgtcaaa ttaaccaaac cttaaagcaa 10980 cctaagaata gtccgtcttc aagggagaga tatgatttaa gtaagctgat tcaaaactag 11040 atgagcgttg tggaaaaaaa ataaacaaac agtcactgtg atatgtttga aaaggcttta 11100 agtaaatacg tgaatgagag agtgtgtata ataaagtgtg cgttggtaaa caaacaaaca 11160 aaaaagcaag tgaaacccaa caacgacgct cggttttttt ttaccaaact aaagatgctg 11220 gggaaataat aaaggtatgt aatgactgtt gaaccttaag agtccgagtg ctcgcatata 11280 tatagtgtga tagatcggtg cttgtttaca tatgtaatcg atcaatctcg catcactctg 11340 aagcgatgat aagatatttg atgatcatta ctcatctttt ctcatattgt cgaaataccg 11400 catgataagg tcggaataag aaataaggat aaggaagaaa ttgttacaac gttaaaaagc 11460 aggtttagtg tgtcgctgga ctacgtaata catatgaacg ggaaaaaagg tcgttaagag 11520 gtattgaagg aacgctaggt attaccggga cagaatgtca aggaagtgtg aatgggcggt 11580 agacatattt gagagaacga aaaaagggat ttgaactatt aaatgcatat ttgggaggtt 11640 gtttgtttgt ttgtttgagt attcgtagcg gattaaagag tcactggccg cattcgttga 11700 gttaacgtgt acgctcaaaa aattagtaag acgatgaatt tggctgactg atcaaaaaag 11760 ttacatcaca actgtttcaa acaaaattaa aaagaaattt ctaattaaat gaatttcaac 11820 ataaagtgat tgaagcggat ccgtggtttc ctccttgcat tattgtaaat gcaaaaaagc 11880 aatcgcatga tttactctaa ggtttgcgac tgttgtgagg aacatttcgt gagtcgccag 11940 tttatttgta tcacatctcc ttttctcaaa ctactgcttc aatcccgtag tggcaaaaac 12000 ataccacaga ctcgggagac atttcttttt cgccagtatg gaaatcgcgc aatgcttata 12060 ctgagcagtc atgatttctt cctgtctgtg ttttatgatt aacttcttat tataaatttc 12120 actttgtcat gatcacccac gaattcaaca ttgtgttgtt tatttcgcaa tttctcagca 12180 tcaagcacgt cgatctcggg tcccttaatc acaatcacgc ttaacttttg atctgataat 12240 ttttgatctg acttcatata agtaacgtgt tccttgtcgg cgttgaggtt aatcgcaatc 12300 atcatcggaa acagagatct tacccgcaaa gtgtatgcat atgtttaagt agttaacgct 12360 ttgtaaatgt atgtctccat gtttagtgcg agatgtctta gattctgaat tgaattttat 12420 agtatcatgc aacatactat cattgatttt ttgcctatct atggatttca caaaattcgg 12480 ctaggtgctt cctaaacttc aaactgatgg ataccgctaa gattcgctgt ctcgtcgttc 12540 tatagcagcc gaaggactat accaattagt cttttttata aagatttcgc gtgcgtttaa 12600 acatgtattc aatcgctttc atttgaaata cagaatgatg catcccatta tgttttgctg 12660 cagaaaacaa acattctttt ttttaccgac cttctgaaaa catataaatc agtggattct 12720 aaatgggtga ttaggaggaa tctactgtat gcgtgttcag aatacaaagc agtaaaccca 12780 ttttgatgat actaatattc ttcgacaggg caagcaaaca ttaaaatgtt aaactgtgaa 12840 tgtttagcaa ttctgagaag cccagccatt taagatcaac atttatttaa agtaaaattg 12900 aaaaccagta gaaaggtcat tttgcttata ttttgcagtt tccaaggtcc attaacgaac 12960 tagcagcgac gtatcatgta cgagttttaa tagaagataa ttcctcccat attctcaatg 13020 tttacggttt tgcgggttta gctcggtcgt ttaatgaaat ttcattgatg aaacttcaaa 13080 ggttagaaga agcaaatcat agattcaagg atttgaatca atctccttta tgttgtagaa 13140 tctttcaaat tcggatcttg agacaatggc gcgttgtaaa aatacaactt aaaggcacta 13200 taaaaatcgt ttatctgaac acatcggctc agcaacgaat cacaatcatt gattttgata 13260 ttgtgccaaa ttcgcagttt tgaaagctga ttgtttatac taatatcgtt acacgcatca 13320 gttttttcaa agagcattgg cgcgcttttt actaacgttt ctcatcaaac gaattataat 13380 tcatatacta tcttcaagta ggtcgatacg attaaaaaga tacaaatgac aatatttgaa 13440 gcatacgaaa gatggagaag gaagtagtta aagcggggcg gattcatcgt taaggtatgc 13500 acaaacagta agcagtcgaa agccgttact gaacttttat ttacaaatat gataaagaaa 13560 tgctctgaaa attattaaac aaggccattt tcctcactat ggctcatata ttgcgtagct 13620 tgactagtag ctaagcatat aaatgcaata ttatggaaga tggaatttta tatgtataaa 13680 attatacatc aactaaaagc aaatacaaaa acaatgcggc atcttctttt tgtatataat 13740 ttagtagagc aagtcagtca actttggacg ttttattttt ttttggcctt cattggttcc 13800 aaataaatag cttaggtcga aagtgtaact agcaaagggg caacaaacac atcatttcga 13860 aaatcgtaca tgattagtta gtataaggag agaagagaag gagtatgcac aacgtggcat 13920 tgataataaa aatcaaaaca accaaagaaa tggctattaa aaatctcgta cactaatcgt 13980 cttcaaacaa aagcaagcca ttacgaaaaa tctcacaagt gattgtgtgg cgtagataac 14040 ttctgaacag gaggatttgc ccattcaagg cactcctctg gagcatcatg agtgcatgta 14100 caatcatcga cagaacagca ttcaatttct tggacaaagg gaagatttaa agcttcttgg 14160 gcagtaattc tttgttcggc agtgggattt gccaaacaga aaaacaaccg ctgcatatgc 14220 atcggaaggt cattgactgg tttaaaatat ggcaaagtct ttgatatacg aatattttgg 14280 acatcgcaaa tgagattgta ctctctccaa gctttacagt atttagcgta caactggtcg 14340 ttctgagaag ctttgcggaa agggtatgtg cgaaaatata gacaatgtaa aacgatagcg 14400 gtagaccaca tatcagcaaa aaaggcattg taagagcctg gtgtcaaaat ttcaggagcc 14460 atgtaggggt cactaccaaa aatacccata ctctttgatt ccacagcagt aatatcatcg 14520 ccgggattgc acaaaacatc acaagcgcca aaatcagtaa ttcttaaaac accatactca 14580 gaaatcaaaa tgttctcagg tttaatatcg cgatgcgcaa taccttggga atggatgtag 14640 ttgagaccac gaagaatctg cttaatcata cactcgaaat cttttttgcc aagacgatcg 14700 tgtcgatctt cgattaaact tagcagatcc cctctgggac aaaagtccat aacagcgcac 14760 cacgtgtcac tataaagagg aaagatatga gaatcaatgc acaaatcata cgatttaaca 14820 acattaggat gctccattct gcattgaacc aaccattctg aggcaagttt agcaatatac 14880 tgaccatcag tttcgtcatc agccttacga cgataggctt tgactgcaaa gcgaaggttc 14940 ttctcatttt ctttgggatt cttaagagtc acgatgcgaa tcacagccgt agcaccacta 15000 cccatatcct tggtctcatc aaccaatttg tattttgcgc tcaatcgagg aacaacgcgt 15060 tttgcatatg gtggaataaa tcctgacttc agcttacggg ggatttcaga aatattggtc 15120 ggaggtttta taggataagt agtaggccca ttgccttggt tgccttcaga agaattggct 15180 gacgtcggac tatttggagc tgtattagcc gaagatccaa cattatcatc agacttcatg 15240 gatgactttc cactatagcc tgggctaaat ggatttgcag ggttaataca atcaaagcca 15300 gtaccttgag gtgtgagctt taaactacca ctaacagcat aggtaaacat atcaaactcg 15360 gtagaatgag gccaactctc gtaagatgta ttggcataat tgtcgcgaac acgcgatact 15420 aatggtttag aagggccagg acggtaggaa gctccagtag aggctaaaga cgacagagat 15480 gggctcttgg acatgctgtt aggagtgcca gtaggggagg atggagtcgg agatgcggtc 15540 aatggaccgt cgaaatagct tccattaccg ccttctcgat ttcgaataga actattcggg 15600 ctaaggggag agggcttctt tctgtaacca ttattaattt ccattggttt agcctttgaa 15660 ggaagttctg ccgatcgaga aagtgattcc ttggcattac cattgggaga cttggttgat 15720 cccaaattgt gagaagccga attggcacgc ctagggactg gttttctagc agttctagaa 15780 tttggaggag agtttttcaa atgttgatag gattgactct tatggatatc cgaagatttt 15840 ccatttactg gagaggaagg gtgggaggaa gtattcttat gaagaatgtg attattaata 15900 aaagagccga accccttgga gggactctcg gaagtggggg aattagcatt gcttttatga 15960 ccaggatgca tagccttttc taagagattt ttaaggccag aatgatgagg tttatgatga 16020 cgcgaagcag atacagggat tggagtagcg ggagctgtgt gcttctgcct agggggggat 16080 ttctgtgggg tctgaagagg agagttattt ccaggtacat gggccatcga gtcagtagtg 16140 tgatttacac gttgctcatg agccgaagat ttgtaatcgg agggtgactt aatttgacta 16200 gaattttttc tactaagaaa gctgtttttg aacttggaaa gccctttgcg aacaggagca 16260 ggagtcccgg agccaataga gcgacttgaa ggagactcac tgtccgatct ttcaggagct 16320 tgtgatccaa tgtcgaaaac gggtttatct gaaggcatta tcaagagaag aaaaagagaa 16380 cttcttttta tttgcggaaa aaatgaaaat agaagagaaa gagtatcaaa aatataataa 16440 acgagcaagt gtaaacacgt ctattcaagc tctctttttc tacttgttct tcctttggat 16500 ggtagatgga cggcgacttt taatcaaaaa aaaggtaaaa acaaaaatag aaaagaaaga 16560 gcaaatacga atttttgatt acaatttttt aaacttagcg aggaaacaca ctgcttttca 16620 attgtgccac ctctcttgtt ttgatgttga atgaacaacg acaatcaaca cggttttttc 16680 ctctgcaaat cttaaaaata ataatcactg caccgttttg aaaccaaata tgtacagaaa 16740 actctattca acagcgtgca agaggtaggg ttgcgcctcg aagtattaaa tcgatcaagt 16800 cttagaaaac ccgaaagcac aaagtatagg tgaaatttca gaattcccaa ctctgattac 16860 accataaatg tagttgtttt atacaattct accttatcaa gctagtgtga agatagcttc 16920 acgtacaagc gtagaaacca caaaggcgat ggtagttgct gtaatccttt cgtaccaagt 16980 agggggaggg acggtaaggt aagtcaatat ctaccgctaa agggtaatat ggattgacgt 17040 tgtatgcaag ggcaagctta acaagacttt atttcaactc cacttatcgt aatttaatga 17100 gatgtgacgt tatggacaat tcaaaaaaat aaaaaaaggc tccgagtatt cctagaattt 17160 tttccaaaca ctgcttttca tacagccaac cgcaacttta ggtaaaaacg attgctcctc 17220 gttaacgcaa gtagaataga atagcgatag atcaagatga aattaaccca agtttgaagg 17280 aggcaattta cctacggaat gaaaagtttg ttataatgaa agtgtgggaa agagacaaag 17340 tagggtgcca cagatgagaa ggaccaaaca atataacgat tgacaaatgc ccgttttttt 17400 ttcttttttt tttttctttg tttatgattc ggctttaaac tactgcaagt ttttgaagcg 17460 gcacttgagg cgttaaagca ttaattaaat cgctgtgacc ggttagtgac aataatggca 17520 actaagtcag atagcaataa atatggtaag agcaagaagg accaaagttg cgaatttgcg 17580 atggagcgga tgaagaatga ggatagatcc gttttagatt tcccaaattc tggagtaaga 17640 aaaataaaat gtggttttaa aatttcgtaa agagagtagc aattatatgt gcttttgtat 17700 tttcgtattt ttccttttat agaaatatcg tgtgtttact gatatatgtt ttctttaaaa 17760 tttatgaact acaattgcga aaattgattc caaactgaca aaacgattga tagtgagaat 17820 tgttgaatca atagttgttt aaagaggaag aaaaagaaag tggaatccat ttatttcttt 17880 gtcattgacg atgattcgtt tagcagcgtt ctgtaaaatg agtagatact attcgtcaat 17940 atggaaaagt aaataaatcc tccaaatccg tcaaaccttg tgcatatttt ttataacgag 18000 gcaaaatgtt caagaaaagt tctaaaattg agcatataaa ataattcaaa tgaaaaaatg 18060 ccatttcaat ataaaatgtc cggcaacacc cagtaacttg cacgtggaag ttgacttctt 18120 ttttcaattg aaccgaagag caattttagc aaaaagccaa ctgtaatgtt gcagatatca 18180 gaaaaacttt taaagtagaa aattttatct tgaaatgtta agctctgggt ccttagaagt 18240 acagggttta attacatacg gctagtaaaa tatcggagga ttttgaagta gctgttaatt 18300 tatagcagaa acgtcagcaa ttgtcaattg attcgagaaa caaggtgtta aaataattaa 18360 ataacccttg gatttagtta ctaactgttt ttaacaaaaa ttgtttgaaa tttttgctgg 18420 caaagcattc tgtcaaaaaa aatggataaa tctgagtatt gaagaagtga taaatggaat 18480 taaaaggaat ttttttccct tcacgtatga gccaaaaagt actcatcgat atagaaaccg 18540 tggtcgattt atcgtaccaa gaaaagagca ttaatcaatc aacgacttgg ttttatttaa 18600 gcaccatgat gaaaacatgc gttttttttt aagattggta gaaactgcat taatccaacc 18660 atgaatagtt aaaatttcat tctaaaattt gtaagattat tgtagtttat gctttaaata 18720 ggctccctac taatcttgtt cgcgctttct ataaaaacag taatggctaa taataatctg 18780 ctaacatgta aaatactatt tctttttccc caattgcttt ttttgattaa gcttaaaact 18840 aataacatgt atcctatctc aaatagctcg agtatttagt ataacgccta actgatttag 18900 tttatgagaa attttatgct tcaaatttac atcttacaga ttctatcaat aaacaattgt 18960 ttgtgtcgct tccttttaca gatataaaga atcaaataag tatttaaaat ataaaaattt 19020 aactcagttt ccacatgaag tttaatatat acattaatat tgtgagacta taacgtgttt 19080 tacccatatt tcagtaattt gtatgatttg tttttgtgac gattatagca atttactctt 19140 gctcttgcaa ttttttgttt gtattttgtt ttttgttcag atatatatat atatagaaat 19200 ataaatttga tatgggctag cgttttaaca tattttttgt ccaatgccac aatccccaat 19260 tcgagtatac tcacatctct cttaaccagt ttatctaaaa aagtgaattt gctttgtggc 19320 tacttctatt tcttctgtaa gtctttaaaa ccctcaagtt attatataga aaaatacatg 19380 agatgagaat tgaaataaat tgggcataaa gatacatttc ctgttagacg catcgtttct 19440 tctttaaata aatttgcctt tcgatatatg caaatgcatc aatggagtgc tcaatttctg 19500 gtcggataat aaaccgagct tcctatcgaa tggtgtcgat ataggaatat taacattgtg 19560 atggagttga actgtaaggt gcgccataat ttacgctgca atttcttttt ttcttaaaga 19620 acttgtatta tttatctaaa atttataatt taagtttgaa acatcttcta atcagacaca 19680 cattaatcgt tttggtcttg atttgctatg ttgaggcaat ggcgttaaac cgcaaatccg 19740 tgttctcaac tatttctaga attctcattt caagaatttg ttttaatcaa taagtgaaag 19800 ttatattaat aatcaatttt agggtgttta gatgtcgact aaagttaagc agaagcaaaa 19860 acaaaaacat cggccaaagc ctagtttgga tcgctctgat tcaactaaac gtgcagctcg 19920 agctgctcga ttttctacga ccttagatgc aaattttcaa gccttaaaaa agaaaaggaa 19980 ggatgagcaa gagtcttttc aggcaaagca atctaccaat tgggaaaaaa gttctgttct 20040 tgttggcact tgtaggcaaa tgtgccctga gtttgaatta gaggaacgta aattacagca 20100 tgctattcac ccatacgagc tggatcctgt gtcaaaacaa gctcacccaa gtttagccgt 20160 aaaggcatac catcgcccag ctgctggtaa aggccctata ttaccatcgg atgtgcgtcc 20220 tccttcaatc cttaaaaaca ccatagacta tttatttaag gtgattttag acagatattc 20280 gttgcgagaa gcacatgcct ttgtaaggga taggacacgc gcagtacgcc aagacttttc 20340 tgttcaatca tcgttttctc aggattctgt ttattgtcat gagttaatag ctagatttca 20400 tatcatatcc ttacatgagc ttgctcacac tcccaacttc agccgtcaac aagaaattga 20460 acagctttcc aaaagtatgg agagtaatta tagtagttta actatttgct aaccattagt 20520 tttgtatact cttgggcaac tatatgatta tatgcatctt cgaaaagagc attgcaccca 20580 tgaagcagaa tttcgcgcgt acatggtatt attaagtctt ggagatccat ccgttggact 20640 cgacacctta tcttggcccg attttgtctt taaaaaacct attgttaaaa catctctcaa 20700 attgtattca ttggctcaaa gaaacaatca tacaataact acctcaaatt ctataagctt 20760 atcattggtg tcttcattta atacggaagc tacatcaaat ttatataccc gtttttttaa 20820 aattgcatcg agctttcgag tttcttattt aatgggatgc ctgttggatt tatttgtacc 20880 ctccattcga actggcgctt taaaagcaat gaaaaaatgt tatctttcag cccattcaaa 20940 cattcccttt aaagatttga tgaagatact agctgccact tcagaagatg agcttgtgca 21000 atgttgtaag atgcacggat taaaaattga atatattgga gagcagccct ccgcagtggt 21060 tttgaacagg aaaactgtaa ttacaggtat gattgtagtt agttgattta taactaattt 21120 tttaaacaga gcctttatta tctagtgaaa tctcttgcag atttgctgat gagaagaaac 21180 ccggtacaaa cgtatcagat ttaatttgtc tagatacgga cggttcaagc ttgcacagaa 21240 aaaaaccgaa attgtttaaa aaaagaagca ttgtgcgcca aaggtagcaa tgtcgcgtat 21300 gcattttcta ataatatttg ggttacaata aatgatacat gttagctttt gttacccttt 21360 tgacaatttt aactgaagga caattgtttt gatgggagat aaagtcagct ttcaaatttt 21420 attgcgttga gtggtagtaa tgctttcatg gaatgtagat aacgggcaga agcaatgtag 21480 agtgaaaatt aaaaactatt ataatacgtc tagggtttcg tgaatgttaa cgttactaac 21540 taaatccaca atctgcgaat gcacatcctc taacgaggaa gaggcatcaa gtgttataaa 21600 ttcgagtccc tcttccctaa actctttttg taatctttgg aaatttttta gaactttctc 21660 ctgcatctct atcttctcat atcgttcttc tccatattgt cctcgagttg cggcaatacg 21720 cggatcaaca tttagaaaaa ttactaaatc ggggcgagga agaccacgat cagggctttt 21780 gcaccattcc caatcgagtc cctacttaat gttagtaact tcatatatcg tctatagagt 21840 ctatatcctc agtcttctgt aattcacgaa ttatccaaga ggagataata taccttagcc 21900 gcagagaatg caataccaga gaatgcgtat ctatctagta tgcaggttac acctttgttg 21960 atttgctcat aaatatattg aatggtttcc catctattgg cagaaaaaag cagatgtatt 22020 acttggtcat tcagctggac cgattccttt agatagtcat caattttttt tccaattgct 22080 gtagttctgt ctatcgagta aacgtaacaa gttagtcggc caagaaacag aaataactct 22140 taccaggaaa tttgaaaagt tcagcctttt catgttgaga aattaactta tcaaccaaaa 22200 gctgacattg ggtagacttt cctgagcggt ctaacccttc gataacaatc aaacgtccac 22260 gattctgttt agacatcaat attaggagtt cttggcagat tactatagat atttattttt 22320 tagtttctct aatcatttca atcttcagaa ttatcgaata ccttttgact acaaaaagaa 22380 cgacttgcta atgtgataaa agctggtaga tccagcttac gtagctaaga gtacatataa 22440 ctcgcgaaaa atgggtaaat gatatgagaa caaaaacgat acattaaact ggcttcatta 22500 aatttataaa acgaaagtta actcccacta tgttaccacg taaatggaga gcacttataa 22560 atgatgtttt tctctaatgg gattttcata tgttaaatca aaaagacata attcattgtg 22620 gtataactag agatgaagaa tgaattactg taagatattt gtgaagtgag aatacgcaaa 22680 agtctaataa caaaatgctt tacttatgtt aacttgggaa ttatagagga ataacctttt 22740 actccttgtg ggcaacaaat ctcaaacgac gatattgtag gaaccattta ccatcgctcc 22800 tacagtcagt caccaacaag gcattataaa ctgtttcacg aatgatgtcc ttccattgtg 22860 gaaaggcgtg atagaaatgc tgtgcaaagg tatctagcca ttcacggacg tctttgttaa 22920 gaagtgttgg tcgagaaatg ttctcaacgt attcaacatg gaatccggcc tcttccaaca 22980 ttcgggtata atcatcctca gagccaaaaa accaaggatt tgcttggtca atctgctcct 23040 ttgtagctcc aagagcaagt agaatagaat aaatgctacc aacaacctct gaaacgttgc 23100 caaaagcacc acattctgcg acgaaacggc ctttggtgcg cagaacccga gaaacgcctt 23160 tcattacgat aggacgattt tttggttgtc gcataatcca gtgcaaagca gcattgctga 23220 agacaacgtc aaaggattcg gatgggatct cagatgcatc aagcaatttt tcgcctggaa 23280 tgacatacgc attcaaacca agttcacgag cagccttaat catgtccgga ctcgcgtcaa 23340 tacctaccac ccgcctgcac tgcgaaacta attcgttggt gagaacacca tcgccgcaac 23400 ccaaatcaag aagttcatca gacgatgaca agtttattct cttaacaatg tctttcgtca 23460 gttttggaac gaaagatgca tttcgctgat agtcctttgc tgacctaatt caattctggc 23520 gttaatattt aacacattac gaatgcatgc ttaccagtaa tcctcaggca ttatgatgat 23580 tgaaatttat aaaaaattca cgaactagta acaaaaaaat atcttctata tataataata 23640 attgttgtcc ttatattgaa gatgaatctt agatacggtg ttaacgtggt tctagtatta 23700 tcatgttatc aatatcatcg gctctcaaat gtagttcaaa taactagaaa cagcatgaaa 23760 caataaaggt taggggttcc aaatttcttt tgaacaggaa gaggtgactt tttaagaata 23820 aaatccgaga aagaagttga aatagatgta gtttaaaatg atttttttcg ctaagacagt 23880 ttaaagaaat aaataaatag atatcgtttc acaaggtcat aaaacaagaa gcagtacatt 23940 aaatttggtt tcataaaagt taagaaatca ttataagatt ttaaaaaagt ttgtgtttct 24000 atagtgtctt catataggca ctgtttgaat acaagcatta atttaagtca aaacatgatg 24060 aaccagatgt ttgaactttt gtttaagttc attctttttg gaatcaggtt gggtaatggg 24120 gactaatgtt tgagcacgca tggctgcagg tctgcgaaaa taaccattac tggcagccgc 24180 acatagcaaa tttgaagaaa tgtctttctt taagctcact gagggtttca aggagcttga 24240 aggagccaac agagttgatt cagtaagttt caattgttta acagaaggcg attgagattt 24300 cgatattaca gttgattcta tcacctcttg ctgtttcact ggcggtttcg aatttgcatt 24360 aacttccttg ttttcacgtt tcaaggatgg cacagttttc aaatttgaga ctcgagcagc 24420 tttctcatta ctggcaggaa cttttccctc tgcgacgtct tgccaagcgc gtatggtttc 24480 taagggtcgt tcatacttcc accgggtggg attattcgta tccggctctg gaaaggatgt 24540 tagtgagaac atggaagtaa gattataaaa tgtgacaact tacgacaaat acttcttccc 24600 gaataatcac gacggacatg cgctttgttt agtttagtgg tttcccgatt tacccgtgca 24660 tacggttcca attccaccaa aggaaagttt agtttctcac aaggaccacc tgcttgcttt 24720 ctcattgcgt ttgactttaa aattcaatca attcctggat aaataaaact ttagaaactg 24780 tgtggttgaa ggcaggttga aaccgcgtcg cgcgttttaa ttatactcag agcgggtgct 24840 agcacgaatc ctctaaaaat caatgaagcc caacttacga acaaccaaca ttcaggtttt 24900 taagatgtta taaaaacgat gaattgttat gacctcaaat tgtttgtttt gaattttact 24960 tgttggcaat gatccgagta ttctaaaagg aaagaattga actcttaatg ttgtaaaaat 25020 aaaaattcat taagtttgaa cgaataaatt tttacaatat atcagaacga atgtttcttg 25080 aacagtttga aatgttgtac ttgtataccg tggataaaac gagtaatttt cagccgaacg 25140 attgcagttt tcagtttgtt ccttaattgc aaataaatac tatcacatgt ttctttaaat 25200 catatttaga tactcctgtt caatgttgaa gcacctagaa gcttccatct ttttcaatac 25260 tcattgcttg agcggtcacc cttgactatt ttcgaaatca aataagttgc caatatgtat 25320 tctttgatat tctatttatt tagagtttct aattctgttg gttcctgttt gtttaatagt 25380 attgttctct acgatatcgc tcatcgatta gcaattaatt aggctccgtt ttagaaactt 25440 cttgtcgatt ctaacagaag gttaaagaac taaattttga atggctcaat tcacgatacg 25500 gtcataacaa cgctatttcg tcaacaaaat ttcaacggtc agttcaatga tttcattatc 25560 cttcaacaat tcatagaaag cgatgaattc tttgcgcggt agcatataag cttcagtatt 25620 atcaatttat tctttcttta aagaaaatag gtaattttta tttaaaacag cgataaattg 25680 ataagtttct tgatatggtg aataagcctc gctacaacac cacagtatct atcctttcca 25740 catcacaacc ctaattacaa attttcatta tttacgggat ttaggttgat tttcggttta 25800 cattttttct tttgcattaa atagaatatg tttttcattg tcgctgcagg ttttgtcatc 25860 gcagctttaa ttgcggctat tggaatggcg atcaatagat tttttgttcg ccgtcgacag 25920 gcaagggctg gacagaccaa accagcaact acacgcccca tggcagaagc tcgcgctagg 25980 cctggcgcaa cagcagttcc tcgccgttca cctacatctc cccagtctgc atacgttcct 26040 gcaactgtat atacatctcc aattggctca cctcgtcgtg gctctgttcg gtatacacat 26100 gtaatggcac acccgaatac aactactacc gtttctgaaa atttgcctga agaagtccca 26160 cctccatata gtccagctgc tactgcaagc aatacacccc aaaatgaagc aagccctgca 26220 gcaaccgaag ctgtaaatca cgaacgacca gcttcaccac caccagttta cagacctcca 26280 gaggaaatgg tttagctttg aatagaaatg agcgattttc tacagtttcg ttaatccttt 26340 ctctttttct ctttacgaaa ctaatttact ttaattttat tatccaaaat aaatccgttt 26400 gttaacttta aaacggaatc ttcatgttga attattgctc tccgatattt ctccatgttt 26460 tacttttgtc attcaatgct tcgatatggc gattttttat gttgccttta gtttatttat 26520 ttgtggtaaa aaagcaggga ttttttacga acatgattac gaatggtttt atggttttct 26580 ttatgaatat tcgatctgga cttcaagaaa ctgatacgtt taatattcca tttcgtgggt 26640 tttcctcttt tattttttaa gttttgtgca ttctatttac tcttttctcc tcaagtatca 26700 cgcatgtttc cttggactta ggattgttta taactttgta cttccaaaaa tttgttaagc 26760 atctgttgtt catttgtaaa tgtatgttaa tgatatattt ccatgcgaag aataatgatg 26820 gcattaatat taataaaaaa taatttcttt aaatcctctc acgatgcgac ctataataga 26880 taattaatca tttccgcggt ttctaaatta gtattccaaa aagtaagact agccacgttt 26940 tagtgactct gagtcagcag tatagctata tactctggag aaaacatagt cacgattgtg 27000 agtgagtggc atttcgttcg tgaatgaggt ataattatgg atggagtaga aagaaatcca 27060 cttaagcctt attccacgaa cttgaagttt ttgaacgtat gtataagttt gacttgcggg 27120 atacacaatt agcatttctc cagaaggagt cattgaccag gagccagtga gtgctacgtt 27180 tccattacta aacataggag aactcgacat aggagaaaaa agactggtgt tttgcacact 27240 gaagttgcga acaacatcat ttggttcatt actgctttga taaacgatac atgttgaatt 27300 aggataaagt cgtaaatacc ggtagtatgt gatcaaatgt atgggttggt tccagctcgt 27360 gtcactagtt ccaggtcgaa agtatcgaca aacggatatg tagcatccgt caaaacgaga 27420 tcgaggcttt ttaaggaaca aagtcttcca gctttgctgg tatttttcca cgagttcttc 27480 ctctattgac ttaatagact gttgccattc tttttgttca caactgcaat aacaaaacga 27540 tctatataga gaatctgctc gtaatgcctt cgcaaaatgc ttacaagtta gtgcaattga 27600 agagagatat cttaaatcat gaaggtccct aatgcaattc tctaggataa ctagcaaaac 27660 ctcgtcggga agcttcagta tattgggaac gaccgactca tttacagact cattttccgt 27720 taacgttgga gatgggactg aggaaacagt gagcatagct tctgatgcat ctgaatttaa 27780 catttcctcc tcttcatttc ttttacacag ttgcaaacgc tccaaacgcc gatagataga 27840 ttccacatct tcatggactt tatgagctaa tcgatattta ttaagagatt cacctaaatt 27900 tccttctctt tcagatttta tagcatcttt gtaatgtaaa agtgcttttt tcaacagtat 27960 atccttgttc actgtttcaa gttcaagaga aagttgatc 27999 //