ID SPCC61 standard; DNA; FUN; 12235 BP. XX AC AL034381; XX SV AL034381.2 XX DT 01-DEC-1998 (Rel. 57, Created) DT 02-FEB-2000 (Rel. 62, Last updated, Version 3) XX DE S.pombe chromosome III cosmid c61. XX KW cystathionine beta-lyase; Golgi membrane protein; KW major facilitator superfamily; spt3; transcriptional regulator. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-12235 RA Lyne M., Rajandream M.A., Barrell B.G., Volckaert G.; RT ; RL Submitted (26-NOV-1998) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and Katholieke Universiteit Leuven, Laboratory of Gene RL Technology, Kardinaal Mercierlaan, 92 blok F, B-3001 Leuven, Belgium XX DR GOA; O14311; O14311. DR GOA; O94347; O94347. DR GOA; O94350; O94350. DR GOA; O94607; O94607. DR SPTREMBL; O94347; O94347. DR SPTREMBL; O94348; O94348. DR SPTREMBL; O94349; O94349. DR SPTREMBL; O94350; O94350. DR SPTREMBL; O94607; O94607. DR SWISS-PROT; O14311; SPT3_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c61 is overlapped at its 5' end by cosmid SPCC622, CC EM:AL033127 and at its 3' end by cosmid SPCC11E10, EM:AL121783. XX FH Key Location/Qualifiers FH FT source 1..12235 FT /chromosome="III" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c61" FT /map="IIIR" FT CDS join(complement(473..684),complement(1..360)) FT /db_xref="GOA:O94607" FT /db_xref="SPTREMBL:O94607" FT /label=SPCC61.01c FT /note="SPCC61.01c, len:189, SIMILARITY:Schizosaccharomyces FT pombe, O74395, major facilitator superfamily protein., (612 FT aa), fasta scores: opt: 339, E():4e-16, (34.6% identity in FT 185 aa)" FT /partial FT /gene="SPCC622.20" FT /gene="SPCC61.01c" FT /product="major facilitator superfamily protein" FT /protein_id="CAA22270.1" FT /translation="MTENYGSMEHRKKSFRNNENLEQQFHPLREELDNAGPINDRTSEL FT SLEGVSKAEAIASTWSKRSIIVAYLGLYLLSFASSLEQQTTYSLQRYATSNFSAHSNLA FT TINLVGNILLAVVRAPMVKAADVFGRSESLSLALGMTVLGYLSLAFSRNIQMFTVAYIL FT YICGQTGLGLLSQLIIADTSSLLNRGIL" FT misc_feature 1..742 FT /note="nominal overlap with cosmid SPCC622, EM:AL033127 S. FT pombe chromosome 3" FT misc_feature complement(361..384) FT /note="ctaacacaatgtcttctcttttag, splice branch and acceptor FT " FT misc_feature complement(467..472) FT /note="gtatgt, splice donor sequence" FT CDS 1692..2615 FT /db_xref="GOA:O14311" FT /db_xref="SWISS-PROT:O14311" FT /label=spt3 FT /note="SPCC61.02, len:307" FT /gene="spt3" FT /gene="SPCC61.02" FT /product="transcriptional regulator" FT /protein_id="CAA22271.1" FT /translation="MTETGRTSKYRVEIQQMMFILGEVQDPLPETTQLVEELIRGQVME FT MLIQANELALRRGSRSITVEDLFFLIRHDRAKVNRLKTYLSWKEVRKKAKEQDANPADT FT KDLFEEVDSKTRSMNAVAMPWEVKNMFTEPVPETEEFEEDNDTMEMAYATRQRLKMADE FT RTKKMTREEYVHWSECRQASFTYRKGKRFREWCGMSILTDTRPDNDIVDILGFLTFEIV FT ATLTEEALAVKDRMDRIQNSSGSGGSHAAHHPKNCSLFDGLTEGRTPLQVSHVLEAFRR FT LQIPDKTHTAMRSFHGGLVKSRVYLI" FT CDS 3343..4326 FT /db_xref="GOA:O94347" FT /db_xref="SPTREMBL:O94347" FT /label=SPCC61.03 FT /note="SPCC61.03, len:327, SIMILARITY:Saccharomyces FT cerevisiae, YKP1_YEAST, hypothetical 37.4 kd protein, (337 FT aa), fasta scores: opt: 626, E():0, (43.3% identity in 321 FT aa)" FT /gene="SPCC61.03" FT /product="conserved hypothetical protein" FT /protein_id="CAA22272.1" FT /translation="MTSGSPKITNLLTRVKRIIPPLLDTFHKGQAGRVGVFGGCQHYTG FT APYYSSMSSMLFGSDQSHIFCEKEAANVIKSYSPDLIVHPFLREKDKAGPEDSVDKCFE FT LIKPMMGRLHAIVIGPGLGRDEWMQEIMAKVIEYARKNDMPMVIDADGLWLIQQRPELV FT SGYHNVILTPNVIEFKRLCDKLDIKSDGPDACNQLAGKLNLLIIQKGQSDIISDGATAY FT ACSVPGGLKRCGGQGDILTGILATFLAWRHAYLSKEWDTEGNMDAKECLFLAAFGASAC FT TRWCSRLAFKECGRATQSTDLVRHVGKAYNALMEDEIPSVEEKIKD" FT misc_feature 3442..4266 FT /note="Pfam match to entry PF01256 UPF0031, Uncharacterized FT protein family UPF0031" FT CDS join(complement(5846..6067),complement(5305..5597), FT complement(5033..5201)) FT /db_xref="SPTREMBL:O94348" FT /label=SPCC61.04c FT /note="SPCC61.04c, len:227, SIMILARITY:Saccharomyces cerevi FT siae, YGR172c, YIPA_YEAST, Golgi membrane protein, (870 aa FT ), fasta scores: opt: 426, E():8.8e-27, (45.4% identity in FT 196 aa)" FT /gene="SPCC61.04c" FT /product="putative Golgi membrane protein " FT /protein_id="CAA22273.1" FT /translation="MAYYNNPANLQYYDYSYTADNSFNTQSRAAGFYDEPLHEPLSQGW FT LAAFSTSGYPGEPSLLEELEINFGHIKQKTTHVLNPFKHVDVHIMDDTDMAGPILFCLL FT FSTFLSLHGRSHFGYIYGIALLGSLSLHFVLRLMSAKNLFFTRTVSVLGYSLLPLVVIA FT FFKNIFTFNGIAGYALAALACIWCTYAASAMFVGILQVNNMRFLVAYPIALFYGVFAVI FT TVFSK" FT misc_feature complement(5202..5219) FT /note="ctaactgtatctttttag, splice branch and acceptor" FT misc_feature complement(5299..5304) FT /note="gtacgt, splice donor sequence" FT misc_feature complement(5598..5613) FT /note="ctaacttcttcattag, splice branch and acceptor" FT misc_feature complement(5840..5845) FT /note="gtacgt, splice donor sequence" FT CDS 8296..9705 FT /db_xref="SPTREMBL:O94349" FT /label=SPCC61.05 FT /note="SPCC61.05, len:469, signal peptide predicted 1-19aa, FT SIMILARITY:Schizosaccharomyces pombe, Q9Y7S5, hypothetical FT 54.3 kd protein., (478 aa), fasta scores: opt: 394, FT E():1.2e-18, (21.5% identity in 447 aa)" FT /gene="SPCC61.05" FT /product="hypothetical protein" FT /protein_id="CAA22274.1" FT /translation="MRINFVLLITLILPWFVSGDSSEEAVDAPLDVKDDTGNKDYYKDS FT TGAYHFDKLIVTPLEYRDGESWKQSVIYCDLIFAKENKEEKGSFVKAQLKEDAEHPFIY FT RLLKLQTPLETYRGFIDGKNTEILDEIKSINLFEDFLSESLVPEISPSVNIPIDETALY FT CFIGIQETEPIRIPWPVLTVEFYGDAPPPESYFRTIKSTLLAISMFLGFITLTWLLRCI FT KSQSGVQPAQISLAFWVFIFVFTHSYQVYSMVAIGRGSFSTWYVVSFLFSLVFEEGLEQ FT SAYTSFLLVLCFGLGITKPALVKYYVYLAFVAFVQGLFVTFAPLSYPVMSFYGVRGILL FT KLIWNIYTFVYYGLPFFAVYRLYKQAGESRKLGFEAKYSLLRTCYIALAAVTVSNCLFL FT GVVRPLLGSQLSLGFQLITSCITFVDFLVFAFLFDCSKFVFLKYQPIPFEWYALESMES FT LNLEPAPDRKV" FT CDS 11932..12235 FT /db_xref="GOA:O94350" FT /db_xref="SPTREMBL:O94350" FT /label=SPCC61.06 FT /note="SPCC61.06, len:100, SIMILARITY:Emericella nidulans, FT Q12607, cystathionine beta-lyase, (439 aa), fasta scores: FT opt: 352, E():3.2e-19, (58.3% identity in 96 aa)" FT /partial FT /gene="SPCC61.06" FT /product="cystathionine beta-lyase" FT /gene="SPCC11E10.01" FT /protein_id="CAA22275.1" FT /translation="MPSDCKYSVDTELVHVEGNEDQYHASSVPIYQSATFKQPCLEHMG FT KFDYTRSGNPTRSVLQVHLAKLMKAKHAFVTSNGMSALDMILRCCKSNSHVVAGHD" FT misc_feature 12232..12235 FT /note="nominal overlap with cosmid SPCC11E10, EM:AL121783 FT S. pombe chromosome 3" XX SQ Sequence 12235 BP; 3850 A; 2110 C; 2188 G; 4087 T; 0 other; agaatccccc gattgagtag cgaagatgtg tctgcaataa ttaattgaga taacagacct 60 agcccagttt ggccgcatat atagaggata tatgctacgg taaacatttg aatatttcga 120 gaaaatgcca atgaaagata tcccaacact gtcattccta atgctaaact aagactctcc 180 gaacgtccaa agacatcggc agcctttacc attggtgctc gaacaactgc taaaagaata 240 ttgcccacca aattgattgt agccaagttt gaatgggcgg aaaagttgct ggttgcgtat 300 ctttgcaaag aatacgtagt ttgctgctct aatgaagatg caaatgacaa caaatagaga 360 ctaaaagaga agacattgtg ttagcttgat cataccacaa acacaaacat tcaacagatg 420 tatgcaaaca ctacgtgatt tatggattat catgactaca atactaacat acccaaggta 480 agcaacaata atcgatcttt tagaccatgt tgaagcaatt gcctcagctt tggaaacacc 540 ttctagtgac aattctgaag tacgatcatt tatgggtcca gcattatcaa gctcttctct 600 aaggggatga aattgctgtt ctaaattttc gttattacga aaactctttt tacgatgctc 660 catgcttcca taattctcag tcatccagag tgtatggtaa atggcagtat gcaaaaggta 720 cgccaacaca aattatcaga tcgtatagca aattagagtt tatctaaccg agatgtttaa 780 tgaagttggt aaacaataat aaataaagac tgatgaaatg cagactagtt agttaataag 840 aggtttttgg ttgctttaag aagcggttaa acttttttaa ataatagaag aattacactt 900 tgaccctttc tccgaggttc aggctaagcc gccaatttga tgttcccgca attaactcct 960 cgaatttatg agtgatggct tcaatagggt attcatttgt tcagagtatt caatttagtt 1020 tctagtcaca cttaaacatt ttggaagtat taaaaattac agagattggt agcagacgat 1080 tttacagcat gctcgaaata gaagcattaa gaagaaattg caatatcact cagactaatg 1140 aaatccttct aaacacgaaa acataatcta aagaattgct agtaatatca caaattgctg 1200 ataattagaa ggtgtttaca tttatggcaa caaagatgaa tgatctagca aaagagagtt 1260 tcagaccaaa gaaagttgat gcttttcact ttatagatta ctcaagtatc tactttaaac 1320 ggaagtaaac aagttacgaa ggtaaaaaat ttcaaacatt tacaatctta aattaataaa 1380 cctatgcttc aaaaaaagac aggagttact cttctaataa cacttcttca ctaactagtt 1440 gtactggatg ttctgtaacg aaagaatgga ctgggtttgc agtttggata gtgtatccag 1500 ctctcataaa atttgtttgc tttttgcaag ctaaacgttt gacaatggtt tttctttttc 1560 aacttaaagc actttatgcc ccatcaatta gtccttctta ctggaaacta tatttttctt 1620 gtcagtttgg agttcagcaa cttgtcaact acccaccact ttgggaagtg gttaaaaata 1680 agcaatgcgg aatgactgag actggcagaa ccagtaaata tcgtgttgaa attcaacaaa 1740 tgatgttcat tctaggggag gtgcaggatc ctctcccaga aaccacacaa ttagtcgaag 1800 agctaatacg tggacaagtg atggagatgt taattcaggc aaatgagcta gctttacgac 1860 gtggctcaag atctattact gtggaagatt tatttttctt aattcgccat gatcgtgcaa 1920 aggtgaatcg actaaagaca tacctgtcat ggaaggaagt gcgcaagaaa gcgaaggagc 1980 aggatgccaa tcctgccgat acaaaagatc tttttgagga agtagattca aaaacaaggt 2040 caatgaatgc agttgctatg ccttgggaag taaaaaatat gtttacagag cctgtaccgg 2100 aaacagaaga gtttgaagaa gataacgata cgatggaaat ggcatatgcg acgcgacaac 2160 gtcttaaaat ggcagatgaa cgcacgaaga aaatgacgcg tgaggagtat gttcattgga 2220 gtgaatgtcg acaagccagt tttacttatc gaaaaggcaa gcgatttcgt gaatggtgtg 2280 gcatgtctat tctaacagat actcgccctg ataatgatat tgtagatata cttggcttct 2340 tgacctttga gattgtggct accttaactg aggaagcact ggctgtgaaa gatcgaatgg 2400 atcggattca aaatagctcg ggtagtggag gctctcatgc agcgcatcat ccgaaaaatt 2460 gcagtttatt tgatggactt actgagggga gaactcccct tcaagtttct catgttttag 2520 aagcttttcg tcgtttgcaa atccccgata aaactcatac tgctatgcgc agttttcatg 2580 ggggtttggt caaatctcgt gtgtatctta tctaatcatt ttcactgtct cttctttttt 2640 tttaattgct gtaaggcttc catttacatc taaatgccct gttttcctgt aattacccat 2700 actaggtacg tatatgttat tatccccatt actggttctc cttgaaacaa tatggtttag 2760 atcttacgaa agccccttta ctttatggag atattaacta ctcaatatat ttcatcacat 2820 tagactgttg tcttgcatct ccgattgaat tcataatttt atttctatct ttccactaag 2880 cgatattctt aattgcagca gtggtagtat ttggactttt ggatttttta atatcaaatt 2940 tttcttatta tactggaatc tcatgatatc tgtgaatatt tgcaaatctt cttaccaaac 3000 ttcgtttact ctatacaaac tgctgatttt cgtaatgaac aaggggatca tccttttgat 3060 atcgtcagtg cgaaattttt aaaaaacaaa gggtttcttt acgttttttt tttgttttcg 3120 agaacatttg aacttcatca ctgagcgtca ttttgatcat accttccacc ttaacatcat 3180 acatacgcca actccaagaa taaccgaaca ttcgtattcc gaagcactca cagtacttaa 3240 gagatacaaa attcaggaat tttaaagact ttttgattta ttataattgt aattctttat 3300 aattttttgc tatccgaaga attcgctcaa caagattaca acatgacatc tggatctccc 3360 aaaattacaa atttgctgac tcgtgtgaag cgcatcattc caccacttct tgataccttc 3420 cacaaaggtc aagccggtcg agttggtgtt tttgggggtt gtcagcacta cacaggtgct 3480 ccgtactatt cttcgatgtc gtcgatgctc ttcggcagtg accaaagcca catattttgt 3540 gaaaaagaag ctgcaaatgt cattaaaagc tattctcctg atctgattgt tcatccattt 3600 ttacgtgaaa aggacaaagc tggaccagaa gatagtgtcg ataaatgctt tgaacttata 3660 aagcccatga tgggaagatt gcatgccatc gtaattgggc ctggattggg acgtgatgaa 3720 tggatgcaag agattatggc caaagtaatt gagtatgcgc gcaaaaatga tatgcctatg 3780 gttatcgatg ctgatggctt gtggttaatt caacaacgtc ccgaattggt ttcgggttat 3840 cataatgtaa ttttaacacc taacgttatt gagttcaaaa gactttgcga caagcttgac 3900 attaagagtg acggacccga tgcttgcaat cagctagctg gcaaactaaa tttgctcatc 3960 attcaaaaag gccaatccga tattatttcc gatggcgcta ctgcatatgc ttgctccgtt 4020 cctggtggtc ttaaacgttg tggtggtcag ggtgacattt taactggtat acttgctaca 4080 ttccttgctt ggagacatgc ttatcttagc aaagaatggg atacagaagg taatatggat 4140 gctaaagaat gtctcttcct tgccgcattt ggagcctctg cctgtactcg ctggtgcagt 4200 cgtttggcgt ttaaggaatg tggtcgtgca actcaatcaa ctgacctggt cagacatgtg 4260 ggtaaagcgt ataatgcgtt aatggaggat gagataccgt ctgtcgagga aaaaataaaa 4320 gattaaaaaa aaataatatt taaaaaccaa gaagataaag gacccttaaa ctaataattg 4380 acttttttgc ttgtttgttc cctggaattg acattattac catgttttca agtcttggtt 4440 caaattccca agcaaaggga taccttaaac ttagttacta ggaatgactg aaacgaaaat 4500 accagattat taatgaaata gcgtatttaa ttttaaaaac catgttcaaa ataaacattg 4560 catagtcgtt ggtatcattg ttgttgagga aatttgatgt agctgtcacc gtttttattt 4620 attgtaacag acaagggcaa gcagactctt ctttttgatt cgtaattgtc attatttaca 4680 ttatcaaatt taacggaaat tagtattgtt cctaagtttt actataagac gatgtatcta 4740 tgagcacgac aatagcttcg gaaaccaatt caaaccttca tataatagtt aaattctaat 4800 attctacgat ttagatatct agattattaa tcaattccta tcttgacctc aacgttgtat 4860 tttcattcta ctgtttttct tcttggaaag tcataattga caatatggaa tattgaaatg 4920 cgttatcaat taaaaatgtt actatttaat ttgaaaaaaa gaaatgtgag ataaaaagaa 4980 agaacatgga taataaatat ctcttttatg ggataaagat gcacagatac gattatttcg 5040 aaaacacggt gatcacggca aagaccccgt aaaatagagc aattggataa gcaaccaaga 5100 atcgcatatt gttgacttgt aagataccaa caaacatagc gctagcagcg taagtacacc 5160 aaatacatgc caaagccgct aatgcgtatc ctgcaatacc actaaaaaga tacagttagt 5220 attaaaaatt cctaaagcat gaaattgtgt aacgattatc taaaatcatt ttaccatata 5280 tcagagatcg atcgactgac gtacttgaat gtgaatatat ttttaaaaaa ggcaatcacc 5340 acaagaggga gtaaactgta tcctagaacg ctgacggttc gagtgaaaaa taaattttta 5400 gcggacatta aacgtaaaac aaaatgaagg ctaagagagc ccaaaagggc aataccataa 5460 atgtaaccga agtgagaacg accgtgcaat gataaaaatg tgctgaataa taaacaaaat 5520 agaataggcc ctgccatatc tgtatcatcc atgatatgaa catcgacatg cttaaatggg 5580 tttaaaacat gagttgtcta atgaagaagt tagcttaacg cgattcattt aaatgatttt 5640 ctaatcagca tctaaaatat gaaagttgaa caaaaaaaga gaatcaatag aaagtttgtt 5700 tctacattaa ttgaaagaaa tattatttta gtaaaaaaaa tatttacaat cttcgatcac 5760 tttcgaattt aacatttcac tacgaaatca ctctttcccg ttcaaccatt caactcttca 5820 agtttttcca tcgtttgcga cgtacctttt gctttatatg accaaaattt atttctaact 5880 cctccaacaa agatggctca ccagggtagc cactcgtgga aaaagcagca agccatcctt 5940 gggacaatgg ttcgtgtaat ggctcgtcat aaaaaccagc agcacgagat tgtgtgttga 6000 aagaattgtc agctgtatag gaataatcgt agtattgtag attagctggg ttgttgtagt 6060 aagccatcga atttaatttt tggtgagaaa cctgctcttg ctaagttagg agagagtagg 6120 agggaaaggt gggtaaaatg gaagctcctc cttttcccct tcaactttga ttaacaagct 6180 ttaaaatagt aatcttctct ttttttttta agaaaaaagc cccagtgtga acagcagcga 6240 gaatttaaga cggtaaggga ttgggatatt tgaaggtatc gttagtccca atgaacttca 6300 tgatattata agatgttctg ttaaactgat gttgaaaatt attatcagtt ctgttatttt 6360 gctcattaat tgaaatgtac tttcggatat catctttgca tgatatcaaa gttacagtct 6420 tttcttaagc tctttgatat tttcatggcc agttctattg acataacaat gaagatgaaa 6480 catataaaat ttatatgaac tattattaca aatgtagatt tctgaccctt gctccaagga 6540 aaattgtgca tatacagagg aaattaaatg taaacattgc tataatacag tataacagat 6600 attttacgag cgaccaaaat tcgtaaggca taatccagcg gctttttaaa aattcgtgga 6660 ttcagctgaa ctgtactatg taaatgacaa tattattgct gttaaaatat ttgagctcat 6720 actttatacc tgtttaaata atacatgaac cgctcaaaac taactttggg atattaagag 6780 gttccaattt atttgattta ttttttaatt gttaacaatt gatttttcta ctccttagta 6840 tatacctcag atggttagta tatgagtcac ttgagctatc gcaaataatt caatacgact 6900 aaacaggtat tcatttattg tatacattaa gaattacttg aattacaata ctaagcttat 6960 ttttagttat tctgacagta aaggaaattt tgaagttatt ggttttattt aatttgaaat 7020 tttttattaa cttacgttac tgtggcacac aaaggtttca tgaaaaagag tatttttgtg 7080 tacctaacac aaattgatta tcagagttat ttttttattg ttctcctatt tcattattta 7140 aacacattta tgtaattatt tacaattaat ggcagcaaaa atttgcattt cataaattta 7200 ctgatataaa aaatccaaaa aaaaaaaata cttctattta tctaaggatc acaagaagct 7260 acaaatagag taaaaaaaaa cttcaagaaa acaacagaag acgattatcg ctattaccca 7320 cgactattta tatcctaatt gtaaattata ttttctttat aatattccat ccatctcgct 7380 aaaaataagc ttaattttaa cggccaacaa tatatacaaa aacttagtgt ctagtttcac 7440 tataataaag aacttacttt ttgctctaga agaaaagaaa aaagaaaaat gaaatgatat 7500 gaagatcttt cactcataaa ttaactgcgg tgtgacaaaa ttagccgtga ctggctcaat 7560 gagagaaatt tgttccttcc aaaaattata ataaaaaagt cccatatgtt gtaaaagtta 7620 aacgaaaaat aaatcgtttc gaagcaagtc tttgtttcct ttgtcagtag taagctgtag 7680 ggatttcagg agtttacacg gaactattat ttctcagttt ttgtcaagca attgaattct 7740 acagtaatct ttgtctttca cttaataaga tatatgtaaa acttaaattt gtctatgtct 7800 ggtgcatagt ttagatattt tcttaaatca tatttttgta gcagttctgt caactcttca 7860 tctaccacca cgtacatata tgtatatttt cattagtagc caattttttt cgacaatata 7920 ggttctaaga agcatataat ttaaaatttt gatttttttc aatccagctc ctcgagaagc 7980 tcatatttat tcatagtttg acggctttct tggtcagtcg tatcaaagca agcgcaaaga 8040 ttcccacatt tttgtactta caataggctt gtcaacgttt actggaggag atttgttaaa 8100 gttaatcaat tcgattagat tattgtttgg attcaggtat tgatcgactc atatttatct 8160 ctacataata ttatatccac ggttttactt ttttaaagtc aaaggcagtc ccatttaagc 8220 caaaagattc gttcgtttct caaaatttaa aaagaaaata tacttaattg agcacttctg 8280 gtaaatcgtt acaatatgcg aataaacttt gttttgctca tcactcttat tttaccatgg 8340 tttgtgtccg gagattcttc tgaagaagcc gtggacgcgc ctttggatgt gaaggatgac 8400 accggcaata aggattacta taaagattct actggtgcct accactttga taaattaatt 8460 gtgaccccgt tggagtacag agatggagaa agctggaaac aatctgtcat ttactgcgac 8520 ctcatatttg cgaaagaaaa caaagaagaa aaaggttctt ttgtcaaagc gcaactgaaa 8580 gaggatgccg aacatccttt tatttacaga ctgcttaaac tccaaacacc gttagaaact 8640 tatcgtggat ttatcgatgg aaaaaataca gagattcttg atgagattaa atcaataaac 8700 ttattcgagg attttctcag tgagtctcta gtccccgaaa tctctccatc agttaatata 8760 cccattgatg aaactgcatt gtattgtttt atcggaattc aagaaactga gccaattcgt 8820 attccttggc ctgttttgac agtcgaattt tatggggatg cacctcctcc ggagtcttat 8880 tttcgtacca taaaatccac cttattagcg atatcgatgt ttttaggatt cattacacta 8940 acatggttgt tgcgttgtat taaaagtcag tccggggttc aacctgctca aatttccctt 9000 gcattttggg tttttatctt tgtgtttacc cattcatatc aggtgtactc aatggttgcc 9060 atcggaaggg gttccttttc aacatggtac gtagtttcct ttttattctc actcgtcttt 9120 gaagaaggat tggaacaatc tgcatataca tcatttttat tggtattgtg ttttggcttg 9180 ggaatcacga agcctgcttt agtgaagtac tatgtttacc tagcctttgt agccttcgtt 9240 caaggtttgt ttgtcacgtt tgcacccctc tcctatcccg tgatgtcctt ttatggggtt 9300 cgaggaatcc tcctcaagct aatttggaat atctatactt ttgtttacta tggattgcca 9360 ttctttgcag tttaccgact gtacaagcag gctggtgaat caaggaaact tggatttgag 9420 gccaagtact ctcttttgag gacttgctat attgcattag ctgctgtgac cgtaagtaat 9480 tgcctatttt tgggagttgt tcgtccctta cttggcagtc aactttcact tggcttccaa 9540 ctgataactt cctgcatcac gtttgttgac ttcttggttt ttgcttttct ctttgattgc 9600 tcaaaatttg tcttcctaaa atatcagccg atcccctttg aatggtatgc actggaatcg 9660 atggaatccc ttaaccttga accagcgccc gatcgtaaag tgtaaaaaag ctttttgata 9720 atcagtttta tattaggtcg agaaaacggt agctgtgtgc gaaaatttaa tccttgaaaa 9780 atggttactt aatatttttt attttacttt tgtggtgaca gttcttacat tttcttgatt 9840 ttcttaattg cacattccca tgagacgcca tttcttgatt ttaatacttg tctttttaaa 9900 ttgctttttt caattactat atctttatcc agatttttta cactatatac tctttcatgc 9960 tattataact ttacaaatac ttccatcctt tatatttttt gctaacacaa tcccattttc 10020 tatacatata aatacgattc agctatattg aattcgtaca actacctcct tgatgatttt 10080 tgctacattt tttctacttt atgccttttt tgatgatgat tttgaatata ttgacacttt 10140 gctaaataat taaacaagct tctcttgata tcctgcatcc atttcaaata gtatcacttg 10200 aaatgttaca taattttaac catgagcatc agcaagaagc gacaatgttt ctaatgcaca 10260 taccatttat cgatttagta atgagaaaag ttaagtttgt taaatagcga tagaacacta 10320 aacgacagta aagataattg catgcactct gtgttattat ggaataccct atatatcagt 10380 ataccaatca cgcaatcggg ttgaactgtt gaatagtttc tggcatgtat ttgtttctct 10440 ctacctttta ccaaaacgga agttggaatg gaagttcgta tgtatgtctg aaaacgtagc 10500 tgtttcattc cgtttaaact aagacttcct taagccaaat aagcagtaaa tgctcaaaca 10560 tatgaaatat tctttaaacc cctaaaaaaa gaagatctaa tacgtaaacc ttgtgttctc 10620 ttactacatt cagacacgca tttttaaatt tgatgaaatt aatgtgtttg tgagcaaact 10680 atagtcatgt gaatgtacgg agatgatatg gcacgatgat tgtggacgta ggtatccaat 10740 attgtgtggg aagtaaattc aaaaaggggc gtctagggga atgattaaac gtttaaacca 10800 cgtacaggaa atcggaacac tgtataggat gttaactgtt ttgagtatca ctagttctga 10860 aacttgcaag gagaatatgt ttattagatg atacagatgt cgttcaagat gttaaagctt 10920 taaatctttg cttatgatta gctctatgtc acccctgtat tttgcttgtg gttcgtatga 10980 ttctgtacag ctcatcgatg aagggtagtg gagtcttgta gatattgggt actactgacg 11040 atagtatccc gaagcagttt tgacctttcg acggcaattg tagtttgcat caatagcgat 11100 tcgagtggat ggatcgccta ttattgtgag ttgtttatta gatgatgtac agttcgcatt 11160 aaagataggc ggtatgtgtc gtgaaatgtg cggaagtttg tggaatttca tgtttaaagg 11220 ggttctcaag ggttagtcga gaagtcgtat ttcttgctaa tatttcatca aacgggctag 11280 atgtgacaac tgttcgttat cgtatgtttg tctttctcac tatattgatg tgttatcaaa 11340 cttactggta acttagttgt tggcgttacc taaacatatt gccatattgc agtagacgtt 11400 tgtgttatta gctgaatttt tcaaatgttt acatcgttta ctcgttcagt acccagtggt 11460 tagctataaa agttattttg ctagcctcat ctgactaaac agaggaaaaa cgctatatta 11520 catttgtcta tcgattcgta tacgtttcca tcagtaaaat cgagcatata atcggcagca 11580 taaaaatcgc aaaaggggtc agggatattg gtcgttctcg ctcgtctaat gttatctgtt 11640 tattgtagcg attatcaaac attttttaca attaggaagc ttcaaaaagt acataaatga 11700 ccatctactg cctgataatc attgttagtt tgtttgccaa tttctaggtc ttaatactcg 11760 tcctaaaaat ttaattttgc aacatctgtt tttgtacacc ttttattgaa ttttggtatc 11820 actgtttctt attaagaaga aaagatttgt tcttcgcttc atatctgtat ctactatact 11880 ctcatattgc ctattttatc ttcctaaatt ttatcttcca tgaccatcac tatgcccagc 11940 gattgtaaat attctgtcga taccgaattg gtacatgttg aaggcaatga agaccagtat 12000 catgcgtctt cagtcccaat ttatcaatca gctaccttta aacagccatg cttagagcat 12060 atgggcaaat ttgattacac tcgttccggt aatcctactc gctctgttct tcaagtgcac 12120 ttggctaaac ttatgaaggc gaaacatgct tttgtaacta gcaatggtat gtccgcttta 12180 gacatgattt tacgctgctg caagtctaat agccatgtcg ttgctggcca cgatc 12235 //