ID SPCC306 standard; DNA; FUN; 25465 BP. XX AC AL049728; XX SV AL049728.1 XX DT 27-APR-1999 (Rel. 59, Created) DT 29-APR-1999 (Rel. 59, Last updated, Version 2) XX DE S.pombe chromosome III cosmid c306. XX KW 26s protease subunit; adenylyl cyclase-associated protein; cap; KW condensin subunit; growth response; malate dehydrogenase; set domain; KW transcriptional silencing; wtf protein pseudogene. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-25465 RA Murphy L., Harris D., Wood V., Rajandream M.A., Barrell B.G.; RT ; RL Submitted (27-APR-1999) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk XX DR GOA; P36621; P36621. DR GOA; Q9Y7R2; Q9Y7R2. DR GOA; Q9Y7R3; Q9Y7R3. DR GOA; Q9Y7R4; Q9Y7R4. DR GOA; Q9Y7R7; Q9Y7R7. DR GOA; Q9Y7R8; Q9Y7R8. DR SPTREMBL; Q9UUN5; Q9UUN5. DR SPTREMBL; Q9Y7R2; Q9Y7R2. DR SPTREMBL; Q9Y7R4; Q9Y7R4. DR SPTREMBL; Q9Y7R5; Q9Y7R5. DR SPTREMBL; Q9Y7R6; Q9Y7R6. DR SPTREMBL; Q9Y7R7; Q9Y7R7. DR SPTREMBL; Q9Y7R8; Q9Y7R8. DR SPTREMBL; Q9Y7R9; Q9Y7R9. DR SWISS-PROT; P36621; CAP_SCHPO. DR SWISS-PROT; Q9Y7R3; CND2_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons o970.seq_emblr CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c306 at the 5' end by c1682, EMBL entry SPCC1682, accession CC number AL031525 and at the 3' end by c4G3, EMBL entry SPCC4G3, CC accession number Z97052. XX FH Key Location/Qualifiers FH FT source 1..25465 FT /chromosome="III" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c306" FT /map="IIIL" FT misc_feature 1..135 FT /note="nominal overlap with SPCC1682 S. pombe chromosome 3" FT CDS 1..>554 FT /codon_start=3 FT /db_xref="GOA:Q9Y7R2" FT /db_xref="SPTREMBL:Q9Y7R2" FT /label=SPCC306.01 FT /note="SPCC306.01, len:>184, SIMILARITY:Saccharomyces FT cerevisiae, SUG2_YEAST, probable 26s protease subunit sug2, FT (437 aa), fasta scores: opt: 937, E():0, (79.7% identity in FT 172 aa)" FT /partial FT /gene="SPCC306.01" FT /product="26s protease subunit" FT /protein_id="CAB41649.1" FT /translation="YIGESARIIREMFGYAKEHEPCVIFMDEIDAIGGRRFSEGTSADR FT EIQRTLMELLNQMDGFDYLGQTKIIMATNRPDTLDPALLRPGRLDRKIEIPLPNEVGRM FT EILKIHLEKVSKQGEIDYEALVKLTDGTNGADLRNVVTEAGFIAIKEDRDYVIQSDLMS FT AARKVADLKKLEGTIDYQKL" FT misc_feature 3..452 FT /note="Pfam match to entry PF00004 AAA, ATPases associated FT with various cellular activities (AAA)" FT CDS join(complement(2061..2126),complement(1547..1996)) FT /db_xref="SPTREMBL:Q9UUN5" FT /label=SPCC306.02c FT /note="SPCC306.02c, len:171, SIMILARITY:, E328824, , (176 FT aa), fasta scores: opt: 445, E():4.1e-24, (42.4% identity FT in 170 aa)" FT /gene="SPCC306.02c" FT /product="hypothetical protein" FT /protein_id="CAB41650.1" FT /translation="MSALSLSITKVSETFSEIYASRAQYLSGFKSVGEFLDVRRISRPR FT NFSEAQSRISFNFSRFSSNYLAIIAMLVIYALIRNPLLLIVIGIGVGGVYGIRKLQGAD FT LQLSHRVISNQNLYVILACVLIPLGLFASPIETIIWLVGASCVCVFGHAAFFEPPVESA FT FETVEQQV" FT misc_feature complement(1997..2013) FT /note="ctaacgcaaaatggtag, splice branch and acceptor" FT intron 1997..2060 FT /note="confirmed" FT misc_feature complement(2055..2060) FT /note="gtatga, splice donor sequence" FT CDS complement(3142..5370) FT /db_xref="GOA:Q9Y7R3" FT /db_xref="SWISS-PROT:Q9Y7R3" FT /label=SPCC306.03c FT /note="SPCC306.03c, len:742, SIMILARITY:Arabidopsis FT thaliana, O80896, putative condensin protein., (704 aa), FT fasta scores: opt: 525, E():8.4e-25, (28.5% identity in 738 FT aa)" FT /gene="SPCC306.03c" FT /product="putative condensin subunit" FT /protein_id="CAB41651.1" FT /translation="MKRASLGGHAPVSLPSLNDDALEKKRAKENSRKQRELRRSSALHS FT ITPRRESLNNSSPFNSSHQVPVLSNFEEWIKLATDNKINSTNTWNFALIDYFHDMSLLR FT DGEDINFQKASCTLDGCVKIYTSRIDSVATETGKLLSGLANDSKVLQQTEEGEDAENDD FT EDLQKKKERKRAQRSVKTLVKDFESIRAKKFELECSFDPLFKKMCADFDEDGAKGLLMN FT HLCVDQHGRIVFDSSDTVIKDLENKDVEAESQEAVVAAPIESHDTEMTNVHDNISRETL FT NGIYKCYFTDIDQLTICPSLQGFEFDSKGNLDVSLLKSLSDEVNMITTTSLVDNTMEKT FT DADAASLSSDSDGEEGHIVHALEEMAYDEENPYVDVVPKAMDESENPDFGVDTEVNMAD FT GSTMNENYSIISTAAANGVYEYFDKSMKKNWAGPEHWRIQALRKNINNASTVFNSSNTA FT ESSDNVSRSLSSTERKKRRELDNAIDFLQEVDVEALFTPATSSLKLPKSHWKRHNRCLL FT PDDYQYDSKRLLQLFLKPKMSVLPNADGEGQLQLNKALDDENDLDGIQPHGFDSDGSDN FT VDEGIPPYGFGDSDSPKQTPLLTPPSSSGFGDNLLLTARLAKPDMLNYAKRAKKVDVRV FT LKEKLWKCLDLENTIKENSINSHIEGSEMESEETNMPVKSFFSTVNQLEETYEKKELKD FT ISTSFAFICVLHLANEHNLELTSNEDFSDVFIRPGPNLTTLEALENDV" FT CDS complement(6068..8830) FT /db_xref="GOA:Q9Y7R4" FT /db_xref="SPTREMBL:Q9Y7R4" FT /label=SPCC306.04c FT /note="SPCC306.04c, len:920, SIMILARITY:Saccharomyces FT cerevisiae, SET1_YEAST, set1 protein., (1080 aa), fasta FT scores: opt: 963, E():0, (28.6% identity in 921 aa)" FT /gene="SPCC306.04c" FT /product="set domain protein; transcriptional silencing" FT /protein_id="CAB41652.1" FT /translation="MDFNTSTRSKSQPVQRNNYKVLYDPELGIKENLGRKIIYRFNGVS FT KPPLVVRDPRLKNPIYARGIPKSGRPFLKSLQTINYDYNENSLGPEPPTQVFVSNISPL FT VTSEQLRYHFKSFGEVFDLDLKLNPYTGTSLGLCCISFDKRSSISVAAHSAKIAVQQAN FT GLRFSGKPLSVVLDRDGSLCEEAFKKALNAVEKQFQEETLQKQRFEREDESSRQKLSAA FT MNEDIPPWRQPSKNSQTLSNGDLQHSKVQNVDQKSGFLTSSETDVPKNINDYIYLLIDD FT RFVPPDRVYYTDIKHHFRKFLYEKIYMNKDGFYITFNNYREASNCYRALDRTYVQNCRI FT KLKFHDIPSRTKEDGKKSAVRRVVLPPEEAYAEATSVVLRDLEAALLRDVKSKIIGPAI FT FKYLHSMPKPSVKEELQENLLVSSTSVPDVPLKIESTVGKLPSLPKFKKRVDSSKMNLS FT AGSKTKSKLQRRRRRRHEARPLHYQLNQMYNSSASEAESDQELLLSSGDERVERGKIGS FT IKSVKSDEATPVFSDTSDENDKFHRFRTKSKISKKKYEKMEVDYTSSSETESDASILSP FT SAAIPKSGSAIKDELISPKKEIDEVLALAPKWRINEFDETGSVYYGALPYNYPEDDVLL FT DLDGLQYLVKNDEDYSYLQEALKDEPLMDINDPNFWAYERKSCKFKNGDVKYGDTAILP FT EPKGYFRSNTSGSAKSEGYYIIPTTEKSLYLPLRNRSTIDTISHSTSRITSRMNRVNNR FT RLAAGVEKSQLPAEADLLRFNALKARKKQLHFGPSRIHTLGLFAMENIDKNDMVIEYIG FT EIIRQRVADNREKNYVREGIGDSYLFRIDEDVIVDATKKGNIARFINHSCAPNCIARII FT RVEGKRKIVIYADRDIMHGEELTYDYKFPEEADKIPCLCGAPTCRGYLN" FT misc_feature complement(6119..6511) FT /note="Pfam match to entry PF00856 SET, SET domain" FT misc_feature complement(8309..8545) FT /note="Pfam match to entry PF00076 rrm, RNA recognition FT motif. (aka RRM, RBD, or RNP domain), " FT CDS join(complement(10308..10880),complement(9919..10082), FT complement(9727..9835)) FT /db_xref="SPTREMBL:Q9Y7R5" FT /label=SPCC306.05c FT /note="SPCC306.05c, len:281, SIMILARITY:Homo sapiens, FT O15503, insulin induced protein 1., (277 aa), fasta scores: FT opt: 245, E():1.6e-09, (28.6% identity in 185 aa)" FT /gene="SPCC306.05c" FT /product="possible growth response protein" FT /protein_id="CAB41653.1" FT /translation="MSRKEIYEPRPRYPDGYNGNRAVKKSLSVLSLDNMKSTLSGLFAP FT LKLDEEQAEDDESLSSYEDYASRQIDDDLKKQRKKGITFIDYSSLITFFCKLCVIFGLG FT FVFTYLAEQIVQDAKLPLLTVNLKSWKFEPPWPAIFGFVAVILGLSYRRMDTKYPLGAA FT PLRPSQSSKWQWISRYLAAFATLLLSMKKLLFISNSHSIVALVASSASIWYIFDRSRNG FT IILSTITSVLGSILYYNLVDTSKIELNGVEFPEIQFRLWIPMILFSASTIVGNAGRLLF FT " FT misc_feature complement(9836..9848) FT /note="ctaacaaatttag, splice branch and acceptor" FT misc_feature complement(9913..9918) FT /note="gtatgt, splice donor sequence" FT misc_feature complement(10083..10097) FT /note="ctaacttatctctag, splice branch and acceptor" FT misc_feature complement(10302..10307) FT /note="gtaagt, splice donor sequence" FT CDS join(complement(12685..12776),complement(11779..12622)) FT /db_xref="SPTREMBL:Q9Y7R6" FT /label=SPCC306.06c FT /note="SPCC306.06c, len:311, SIMILARITY:Saccharomyces FT cerevisiae, YHQ1_YEAST, hypothetical 39.1 kd protein in FT hxt5-nrk1 intergenic regionprecursor., (335 aa), fasta FT scores: opt: 141, E():0.028, (26.1% identity in 199 aa)" FT /gene="SPCC306.06c" FT /product="hypothetical protein" FT /protein_id="CAB41654.1" FT /translation="MFSWSILFIVCFSLVSAFKDTSPIFLFSTNSKLPKSSDDSSISTC FT PMMFFDAAIEALSTCNTATLIIHQPGLEVNDFQLGAFKHLKRVSLQSPYSLLLPYSKES FT LDSQELVHSAKQNCDVEVVYLGGSFNAFPPLQNDRITVVYMNELSNESYHRSAQLMELD FT EMFYNLQSTLEQDAQWNVIIASSPLNNSDFEGFKVDANEEEANAEFVIQTLGGLNSGKS FT ALQHGQLASLPDQNEGSQTTLAMHQTRKHPVTDNGATGLFTEYQFFTPGLYMGYLALAV FT LVPTLFISCRLLSSIQISYHAFDSPRRKQL" FT misc_feature complement(12623..12636) FT /note="ctaactaaaaacag, splice branch and acceptor" FT misc_feature complement(12679..12684) FT /note="gtatgt, splice donor sequence" FT CDS join(complement(14376..14438),complement(14182..14315), FT complement(13303..13960)) FT /db_xref="GOA:Q9Y7R7" FT /db_xref="SPTREMBL:Q9Y7R7" FT /label=SPCC306.07c FT /note="SPCC306.07c, len:284, SIMILARITY:Homo sapiens, FT O76021, pbk1 protein., (516 aa), fasta scores: opt: 336, FT E():3.8e-15, (30.4% identity in 280 aa)" FT /gene="SPCC306.07c" FT /product="hypothetical protein" FT /protein_id="CAB41655.1" FT /translation="MAITSEKKKNLKSLDKIDIKLLEKTIRALLQHIRSSDKPIEKEKV FT YIQVNTFQPVEKESLRRPSKVFLPHRIMHVTDACLIVKDSQQTYQDLVEQQGLDEVITK FT VLSIPRLKLKYKTIREKCELRDSHNLFLVDDRVLKYIPLLMGKVFEQKKIKPFPISVLQ FT KKETLRNQVARCLHSTYLKLSAGTSHTILCGLATQTNEQLLENITTVLKCLLTNFIPKG FT WSAIDNVAIKTADSASLPIWTSDTNLAAHKRHIVHIQDARPLKKSELRAQKRGSSGEGK FT GNK" FT misc_feature complement(13961..13975) FT /note="ctaactattttacag, splice branch and acceptor" FT misc_feature complement(14176..14181) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(14316..14333) FT /note="cttacaaataatcaatag, splice branch and acceptor" FT misc_feature complement(14370..14375) FT /note="gtaaga, splice donor sequence" FT CDS complement(15006..16031) FT /db_xref="GOA:Q9Y7R8" FT /db_xref="SPTREMBL:Q9Y7R8" FT /label=SPCC306.08c FT /note="SPCC306.08c, len:341, SIMILARITY:Saccharomyces FT cerevisiae, MDHM_YEAST, malate dehydrogenase, mitochondrial FT precursor, (334 aa), fasta scores: opt: 1262, E():0, (59.8% FT identity in 331 aa)" FT /gene="SPCC306.08c" FT /product="malate dehydrogenase, mitochondrial precursor" FT /protein_id="CAB41656.1" FT /translation="MFAKVAFKNFTPLKSIAPRSFSTTSSRAFKVAVLGAGGGIGQPLS FT MLLKLNDKVSELALFDIRGAPGVAADIGHINTTSNVVGYAPDDKGLEKALNGADVVIIP FT AGVPRKPGMTRDDLFATNASIVRDLAFAAGETCPEAKYLVVTNPVNSTVPIFKKALERV FT GVHQPKHLFGVTTLDSVRASRFTSQVTNGKAELLHIPVVGGHSGATIVPLLSQGGVELT FT GEKRDALIHRIQFGGDEVVKAKAGAGSATLSMAYAGARMASSVLRALAGESGVEECTFV FT ESPLYKDQGIDFFASRVTLGKDGVDTIHPVGKINDYEESLLKVALGELKKSITKGEQFV FT A" FT misc_feature complement(15021..15944) FT /note="Pfam match to entry PF00056 ldh, lactate/malate FT dehydrogenase" FT CDS join(complement(19521..19579),complement(17850..19446)) FT /db_xref="GOA:P36621" FT /db_xref="SWISS-PROT:P36621" FT /label=cap FT /note="SPCC306.09c, len:551" FT /gene="cap" FT /gene="SPCC306.09c" FT /product="adenylyl cyclase-associated protein" FT /protein_id="CAB41657.1" FT /translation="MSDMINIRETGYNFTTILKRLEAATSRLEDLVESGHKPLPNMHRP FT SRDSNSQTHNISFNIGTPTAPTVSTGSPAVASLHDQVAAAISPRNRSLTSTSAVEAVPA FT SISAYDEFCSKYLSKYMELSKKIGGLIAEQSEHVEKAFNLLRQVLSVALKAQKPDMDSP FT ELLEFLKPIQSELLTITNIRDEHRTAPEFNQLSTVMSGISILGWVTVEPTPLSFMSEMK FT DSSQFYANRVMKEFKGKDDLQIEWVRSYLTLLTELITYVKTHFKTGLTWSTKQDAVPLK FT TALANLSASKTQAPSSGDSANGGLPPPPPPPPPSNDFWKDSNEPAPADNKGDMGAVFAE FT INKGEGITSGLRKVDKSEMTHKNPNLRKTGPTPGPKPKIKSSAPSKPAETAPVKPPRIE FT LENTKWFVENQVDNHSIVLDSVELNHSVQIFGCSNCTIIIKGKLNTVSMSNCKRTSVVV FT DTLVAAFDIAKCSNFGCQVMNHVPMIVIDQCDGGSIYLSKSSLSSEVVTSKSTSLNINV FT PNEEGDYAERAVPEQIKHKVNEKGELVSEIVRHE" FT misc_feature join(complement(19521..19540),complement(17853..19446)) FT /note="Match to PF01213 CAP, CAP protein" FT misc_feature complement(19447..19465) FT /note="ctaacatttactcatatag, splice branch and acceptor" FT intron 19447..19520 FT /note="confirmed" FT misc_feature complement(19515..19520) FT /note="gtatgt, splice donor sequence" FT misc_feature join(20748..20886,21055..21300,21350..21593,21639..21830, FT 21871..21933,21984..22066) FT /note="c306_gf6, pseudogene" FT CDS join(20748..20886,21055..21300,21350..21593,21639..21830, FT 21871..21933,21984..22066) FT /label=SPCC306.10 FT /note="SPCC306.10, PSEUDOGENE, FT SIMILARITY:Schizosaccharomyces pombe, O74474, hypothetical FT wtf3 protein., (329 aa), fasta scores: opt: 1402, E():0, FT (66.9% identity in 329 aa)" FT /partial FT /pseudo FT /gene="SPCC306.10" FT /product="hypothetical wtf3 protein." FT misc_feature 20887..20892 FT /note="gtaaga, splice donor sequence" FT misc_feature 21042..21054 FT /note="ttaatttaaacag, splice branch and acceptor" FT misc_feature 21301..21306 FT /note="gtaagt, splice donor sequence" FT misc_feature 21338..21349 FT /note="ctaactcattag, splice branch and acceptor" FT misc_feature 21594..21599 FT /note="gtatgt, splice donor sequence" FT misc_feature 21628..21638 FT /note="ctaacacgcag, splice branch and acceptor" FT misc_feature 21831..21836 FT /note="gtttgt, splice donor sequence" FT misc_feature 21858..21870 FT /note="ctaaccgtatcag, splice branch and acceptor" FT misc_feature 21934..21939 FT /note="gtatgt, splice donor sequence" FT misc_feature 21971..21983 FT /note="cttacccgactag, splice branch and acceptor" FT CDS 24091..24942 FT /db_xref="SPTREMBL:Q9Y7R9" FT /label=SPCC306.11 FT /note="SPCC306.11, len:283" FT /gene="SPCC306.11" FT /product="hypothetical protein" FT /protein_id="CAB41659.1" FT /translation="MFAFASFAISAIFFLCSFSYVSSIKLCGIPGAPACKRREISLYKR FT ATDTFPDLSSAIASTSYYNISEGTYCHVSGSNLCVSPDVIAICANHSTVLLNCPTVLGY FT PKGRGSACVETNSSYGLTRGLCQIGSSNYSTSANSSNFDNANVINVTTSVSSGSTSTHS FT KRSSGISLSYTNIVDQPILFTRDSSMDWSCNMTLCNTDYPYLVNTCFNGTQYPVNCNSA FT LRTPFGGATCRNIGYKGQGICVYTNDSRIPVADDHVIVNTTSKINPNITSVFNYRDNAF FT LW" FT misc_feature complement(25344..25465) FT /note="nominal overlap with SPCC4G3 S. pombe chromosome 3" XX SQ Sequence 25465 BP; 8212 A; 4698 C; 4560 G; 7995 T; 0 other; aatatattgg agaatctgct agaataattc gtgaaatgtt tggctatgca aaagagcatg 60 agccatgtgt tatttttatg gacgaaattg atgctattgg tggtagaaga ttctctgaag 120 gaacatctgc tgatcgtgaa attcagcgta cattgatgga attattgaat cagatggatg 180 gtttcgatta ccttggccaa acgaaaatta tcatggcgac aaatcgtcct gatactctag 240 atcctgcctt gcttcgtcct ggtcgtctag atcgtaaaat tgaaattccc ctaccaaacg 300 aagttggtcg tatggagatt ttgaaaatcc atttagaaaa agtctctaaa caaggcgaaa 360 ttgactatga agcattggtt aaactgacag atggaacaaa tggtgctgac ttgcggaatg 420 tggttacaga agcaggattc atagccatta aagaagatcg cgactatgtc attcagtccg 480 atttaatgtc cgcagctcgt aaggttgctg acctgaagaa acttgaaggt acaattgatt 540 accaaaagct ttagtgcaca tatatccaaa aagccatgaa atgataagtt taccgatgaa 600 gattatacgc gcaactgcat agttatgatt aaaaaggtcg aatagtaagt gaaacgttta 660 cttttaatat attccgactc ttttggcttt tatcatgtat atatgaatat gcttgatggg 720 aatctatgta tattatcgta aggcatatct gtgatagtac aaactgattt tcttcaatat 780 ttgattatgt tttccatatc ctccaaatac caaacattgt ttttccactc tacataattt 840 actggcgaca aaagaaaaaa tgatcaagta aaaataaaca attaattata cacatgaatt 900 aaaagtaaag caaatgtttg actagaaatt attaactaac caaatgcact gaagtgtaaa 960 gaacgaacta aatatattga acgaaacccg gttcaaaaat gcaaaaattc ttctcttccc 1020 aggaaggata gtttgaagtt atccttaaaa ggtagtagac ctttgacaaa gaaacgagga 1080 aaaacgtcta gtacgctaag ataaaagaat aagagaggtg aaaatcatag ctggcttcat 1140 ataagcagcc aaactagtta ttatagtact agatgaagct gaatgcgcag tttagaagtc 1200 attttatccc ataatttcaa gaaagtaaag gcaagataaa gatagccaga tagagtcatt 1260 gaaaaagacg acgaaaaggc gtaaaacaaa gagcgcagaa atgaataatc taaaaaatta 1320 caaatgaagt attaacgtat taaaaggaaa aaagtatgaa acgcaaataa ctgataataa 1380 aatgattagc aagctagttt ctttaaaatc ggcgtacagt ttccctcttt ttgtttgtca 1440 aagaagagta agcgtaggaa atgccagtat tccctttgta aagacatgta cgaaaattaa 1500 agcaactgta ccaagataac caaagaggct gttagaaaca atttttttag acttgttgct 1560 cgacagtctc aaatgccgat tcaacaggag gctcaaagaa agcagcgtgt ccgaatacac 1620 agacacagga agcaccaact aaccaaatga tagtttcgat gggagatgcg aacagcccaa 1680 gaggaatcaa cacgcatgct agaatgacat aaagattttg gttggaaatt acacgatggc 1740 taagttgtaa atcagctcct tgaagcttac gaataccata aacaccacca acaccaattc 1800 caatgacaat taaaagtaaa gggttacgga taagtgcgta aataacgagc atagcaatga 1860 ttgcaagata gttagaagaa aacctcgaaa agttgaagct aattctcgac tgagcttcac 1920 tgaaattcct aggtctagaa attctacgaa catccaagaa ctcgcccacc gatttaaaac 1980 cacttagata ctgagcctac cattttgcgt tagtgaattg atcttttcaa gtttactact 2040 catagttcat taattcatac ccttgaagcg taaatttctg agaaagtctc cgaaacttta 2100 gtaatactca acgacagtgc tgacattatg aaaaaccgta gtaggtgtct tagatatagg 2160 gaaaggataa attctacttt tcctggatgt tgacaaagta ttctaagcca ttgattgtta 2220 cccactgtaa agtacattga gaaagcaacg ctaaatagat attgtgcaac agaaaaaatt 2280 gtaataattg tattgcataa ctcattttat ttaaattatg aatcactatc gtatatagcg 2340 taattttgct ttaaacgcta tttcaaatct atggtaaaac tagatgaact aacgttgctg 2400 cgaaagttca tagattgctt ataaacctat ttctttaact aaaaggatgt attttaactt 2460 tattttactg agccaaagtc cattcgttga cggtgttgaa attattctac agcttggtca 2520 ttgacaaatt tcattttctc tgataattca tttaataatt tgtatcaaaa aaaaatagat 2580 tcttgagaaa gattaacata aaagataaaa ttaccctaca tttctgtact caaatcgata 2640 tgttctaact ttgaaagggt ttcacaatat atgaataacc gtatattggt acaatttaat 2700 cctattatag gtaaaaaacc tcacatagag acaataaata attattattt tttgttatat 2760 tgtcgagaat agaagcatgt aatgaatgca atatctcgtt atttccaaag agtcaactgc 2820 taagtgagtt ccaacagaat taacaggcag aagcaagata ctgatgtctt caacgatcac 2880 aagataaaag gaaggtgtat tttttacaaa aaatttcgct gtcagcttgc tccacaaaat 2940 gcaatttgca ctcttcattt ttcacaactc ttcaatgtca aaaagtagta acagcctaaa 3000 aatacgagct agtgttttta ttattcaagg tagatcaaaa agagtataat ttccggctat 3060 cttgaaaatg attcacgcta gctaaaagta tgcgatgatg actaattaat gatgacctgc 3120 atcatttcga ttctacacac tttaaacatc attttctaat gcttctagcg tcgtcaagtt 3180 aggacctggc ctaataaaaa catctgaaaa atcttcgttg cttgtaagct ctaaattatg 3240 ttcattcgcc aaatgtaaaa cacaaataaa ggcaaaactg gtggatatat ctttgagttc 3300 ttttttctcg tatgtctcct ctaattgatt gacagtggaa aaaaaagatt tgactggcat 3360 gttggtttct tctgactcca tctccgaacc ctcaatatga gagttgatgg aattttcttt 3420 aattgtgttt tcaagatcta gacatttcca tagcttttct ttcagtactc gcacatcaac 3480 ctttttagca cgcttcgcat aattcagcat atctggtttt gccaaacgag cagttaacaa 3540 aaggttatca ccaaatcctg atgatgatgg aggtgtaagc agaggtgttt gcttagggct 3600 atcggaatct ccaaatccat acgggggtat tccttcatca acattatcac tgccatcaga 3660 atcgaatcca tggggttgaa taccgtccaa atcattctca tcatctaagg ctttattcag 3720 ttgtagctgt ccttctccat cagcgttggg tagaactgac atctttggtt tcaagaaaag 3780 ctgtaaaagc ctcttagaat catattggta gtcatcaggt agtaaacatc gattatgtct 3840 tttccaatga gacttgggaa gcttgagact gctggttgca ggagtgaaca gtgcttcgac 3900 gtctacttcc tgcaagaaat caatggcgtt atcaagttct cgacgctttt tccgttccgt 3960 ggaagaaaga gaacgcgata cattatctga actttcagcc gtattggaag agttgaatac 4020 agttgatgcg ttattgatat tttttctcaa tgcctgaatg cgccaatgtt cgggtccagc 4080 ccagttcttt ttcattgact tgtcaaaata ttcgtatact ccattcgcag cggcagtaga 4140 aataatagaa taattttcat tcatagtact tccatcagcc atattgactt cagtatccac 4200 accaaaatct ggattttcgg attcgtccat tgcttttggt actacatcaa catatgggtt 4260 ctcctcatcg taagccattt cctccaaagc atgcacaata tgtccttctt caccatcgga 4320 atcggaagaa agggaagctg catcagcatc agttttctcc atcgtattat ccactaagga 4380 ggttgtcgtt atcatgttaa cttcatcact taatgatttt aagagagaga catcaagatt 4440 ccctttacta tcaaattcaa agccctgtaa ggagggacat attgtcaact gatcaatatc 4500 ggtaaaatag catttgtaaa taccattcaa ggtctcccta gaaatattgt catgcacatt 4560 agtcatttct gtgtcatggc tttcgatagg cgctgcgact accgcttcct gcgattcagc 4620 ttcaacatct ttattttcca aatccttgat gacagtatcg ctagaatcga atacaattcg 4680 tccatgttga tcaacacaaa gatgattcat taataagcct ttagcaccat cctcatcaaa 4740 atctgcacac attttcttga ataaaggatc aaaagaacat tctaactcaa attttttagc 4800 gcgtattgac tcgaaatctt taacgagagt ctttaccgaa cgttgtgcac gctttctctc 4860 tttctttttc tgtagatcct catcatcatt ttcagcatct tcgccttctt ccgtttgctg 4920 caatactttg gaatcgtttg ccaatccact gagtagcttg ccggtctcag tagcaacaga 4980 atcaatacgc gaagtataaa ttttcacgca tccgtctaat gtacagcttg ccttttggaa 5040 atttatatct tcaccatcac gtagaagcga catgtcgtga aaatagtcaa taagcgcaaa 5100 attccaggta tttgtggaat taattttgtt gtcagtagct aatttaatcc attcctcaaa 5160 attagaaaga acaggaacct gatgagagct attaaatggt gaagaattgt ttagagattc 5220 tcttcttggc gttattgagt gcagagctga acttcttcgc aactcgcgct gcttacggct 5280 gttctcttta gctctttttt tttctaatgc atcgtcattt aaggagggta agctaacggg 5340 cgcatgcccg cctaaactag ctcttttcat tgatttaagt aaatgtttat gttcacaagt 5400 ggtaagtcgg tgtgcctata cgtatatcgc gctttaacga tatgccgtat atttctttct 5460 aatcaacaaa tgataaagat tcaaataagt ttctaaataa atgccaatat gataacatta 5520 tttttctttt gaaatttgtt ttcaaataat atagtatttc ccaatttact tcattgatgg 5580 cttcccgatt acaaagtcaa aagtcttttg tttattattc tgttacaaat tttgtgaagt 5640 ttcaattatt ataaatcttc catataaaat taacaaggta ataccaaatc aagtttggat 5700 cctaaaattc agtagctatc aagttttaag agaattttat ttttcgtttt cgtttattta 5760 aacttgaact tcgtagtatt gtggagcaaa tggatatatc taagacagta tatctcttaa 5820 cattttactt ctaaatcact cctgaatgca atccactgaa tggtatgcgc atttatcctg 5880 actctcaaaa tattcaacca atatcaaatg cagacgatgt aagacagaaa attgattcta 5940 ttctatatta aaaaataaaa agcattagtg taccatcaga tataatgcgt gctttttaaa 6000 cgaactatta taattgtaca gctgcccata tattcatgta ccatcaattc tccaagagca 6060 tcattgtcta gtttaaatag ccacgacatg ttggagcacc acacaaacaa ggaatcttat 6120 cagcttcttc cggaaacttg taatcataag taagttcctc tccatgcata atatccctgt 6180 cagcataaat tacgattttt cttttccctt caactctaat aatcctagct atacaattag 6240 gagcgcatga atgattgatg aaacgcgcga tatttccctt ttttgtagca tcaacgataa 6300 catcctcgtc aatacggaac aaataactgt ctccaatacc ttcacgaacg tagttctttt 6360 cacgattatc agccacccgt tgtcgaatga tttctccaat atactctatg accatatcat 6420 ttttatcaat gttttccatg gcaaaaagcc ctaatgtatg aatgcgacta gggccaaaat 6480 gtaattgctt tttacgagcc tttagtgcat tgaatctgag caagtcagct tcggctggca 6540 attgagactt ttcaactcca gcagccaatc ttctattgtt aacacgattc attcgtgatg 6600 tgatacggct tgtagaatga ctaatagtat cgatggttga tcgattacga agtggtagat 6660 atagtgattt ttcggtagtt ggaataatat agtatccctc acttttagca gaaccgctag 6720 tattagagcg aaaataacct ttaggttctg gaagaatagc cgtatctcca tacttaacat 6780 ccccattctt aaatttacat gacttgcgtt cataagccca gaaattggga tcgttgatat 6840 ccatgagggg ttcatccttg agtgcctctt gaagatatga gtaatcttcg tcatttttta 6900 ccaagtactg tagaccatcc aagtcaagaa gtacatcgtc ttctggataa ttgtaaggaa 6960 gtgcaccata ataaacgctt ccagtttcat caaactcatt aatacgccat ttgggagcta 7020 aagctaaaac ttcatcaatc tctttcttag gcgatatgag ttcatctttt atggcgctac 7080 ctgattttgg aatcgcagca ctaggagaaa gtattgatgc atctgattcg gtttcgctgg 7140 acgaagtata gtcaacttcc atcttttcat attttttctt tgatatttta gattttgtac 7200 gaaaacgatg gaatttgtca ttttcatcag atgtatcaga aaaaactgga gtcgcctcgt 7260 cagacttcac agactttatt gagccaatct tccctctttc tacacgctcg tctccagaag 7320 ataacaaaag ttcttgatca gactcggctt cagaagcgct tgagttatac atttgattaa 7380 gctggtagtg taaaggtcga gcttcgtgcc ttcttctacg tcttctttga agtttcgact 7440 tcgttttact acccgctgaa agattcattt tactggaatc aactcgtttt ttaaatttgg 7500 gaagactggg gagctttccg actgttgatt caatttttaa aggaacatca ggaacacttg 7560 tagatgaaac caataaattt tcttgtagtt cttccttaac agaaggctta ggcattgaat 7620 gaagatattt gaagattgcc ggtccaatta ttttactttt tacatcacgt aacaaagcag 7680 cctcaagatc tctaagcaca actgaggttg cttcagcgta cgcttcctcg ggaggtaaaa 7740 caactcttcg tactgcgctc ttttttccat cttcctttgt acgtgaagga atgtcatgaa 7800 atttcaattt tatgcgacaa ttttgtacgt atgtacgatc cagcgcacgg taacaattgc 7860 tcgcttcgcg ataattatta aaagttatat aaaacccgtc tttgttcatg tatatctttt 7920 catacaaaaa ttttcgaaaa tgatgcttta tatcagtata atacacacga tctggaggga 7980 caaagcgatc gtcaattagt aaataaatat aatcattaat attttttgga acatcagtct 8040 cgcttgacgt aagaaaacct gatttctggt ccacgttctg aactttagaa tgttgcaagt 8100 ctccattgct caatgtttgt gaatttttcg atggttgacg ccaaggagga atatcttcat 8160 tcatagctgc agataacttt tgccgcgaag attcatcttc ccgctcgaat ctctgtttct 8220 gtaaagtttc ttcttgaaat tgcttttcaa cagcatttaa agctttcttg aacgcttctt 8280 cgcataatga accatcccga tcaaggacta ctgaaagagg cttaccggaa aacctcaagc 8340 catttgcttg ttgtacagca attttcgctg aatgtgctgc tacagaaatg gaactacgct 8400 tgtcaaaaga tatacagcac aaccctaaag aagtacctgt ataagggttt aactttaagt 8460 ctaaatcgaa aacttcccca aatgatttaa aatgatatcg gagctgttca gaagtcacga 8520 gcggtgagat gttagaaaca aaaacctgag ttggaggttc tggacctaat gaattctcat 8580 tgtagtcata atttatagtt tgcaaagatt ttaaaaatgg ccttccactt ttaggaatac 8640 cgcgggcata tattggattt ttaagtctag ggtcgcgaac tactaaaggt ggttttgaaa 8700 caccattaaa ccgatatata attttgcgac caaggttctc cttgattcct aattctggat 8760 cgtataaaac tttgtaatta ttcctttgaa cgggttgaga tttcgaccgc gtagaggtat 8820 taaaatccat ggctgattaa tattgaatcc aagtagcaaa tcccaggcat tcgatcaaaa 8880 caaaaaagag ctataaagta aaaaaaaaaa aaaatcaaga gatattaaaa acctgtgcac 8940 taaatcaaaa tcaaaaattt ggtaacaact cgataagtgt aatttattcc aataatgagc 9000 cttgacaaat tatgaaaaaa aaaacgttat gtaaaaagaa ataatatcgc cgggatgaag 9060 agctttctat tgtaaagtat ttgaaccgta attcagctta taattggaaa agtatgtcgc 9120 gcgacgttac tttgtaaatt ataacaatat tcaaaaactc aagtaaaact tgatcagtct 9180 tcaaataaat acgttcataa ggctaataac aagtaaaaaa gctctgtcaa acatccgttt 9240 ggccaaacac aaagtttata ggatctctgt ggatgtttgt gtaaggtagg ccaattcata 9300 ttacgcgcca cagtagctct tatagcgaaa tttagtaaaa tcgttatcca aagataccgt 9360 tgcatattac actaccaatg ttgctgaaga gaagcaagaa taaatggctt gagaaaggaa 9420 aacttgtaga tgaatgtttt agaacaaaga cataattata aactacatga ggaatattag 9480 gaatcataat agaaaatact aacatgaaaa gattgttggt acatgataga aaaccgattc 9540 gcacacaacg atgaatgaga cgagaaggta caaaaggata atcgaataca gaaaaaccaa 9600 ataagtgccc agatgcgaag taggaaaaca tttagcaaaa caagtttaac ccggttgttt 9660 tggataatga agtctaaggc taaaaagaga acgtaaagca caaacaacca actcctagag 9720 aataaattaa aatagtagac gaccagcgtt accaacaatc gtagaagcgg agaaaagtat 9780 cataggaatc cataaacgaa actgaatttc agggaattca actccattta actcactaaa 9840 tttgttagct gataaacgaa tgtttgaaaa tactggagca gcctttggta ggcagttgat 9900 ggataacaac taacatacat ttttgaggta tcaaccaaat tataatataa gatactcccc 9960 aacacagaag taattgtcga caaaataata ccgtttcttg agcgatcaaa tatataccaa 10020 atgctagcag aactcgcaac gagtgcaaca atggagtgtg aattcgaaat aaatagtaat 10080 ttctagagat aagttagcaa gagtatattc acgatgcata gtaagcattg gcaaagaggg 10140 tttactatca aacttaaatt ctcagaaaac agcacaactt atttatggtg atgaataaac 10200 tatatcaaga agtcgttacg catagataat tgctgtaact ccatacatct tgcatatata 10260 tttcactttt ttatttaaag gaacgcctcg tataatgtaa aacttacctt catagaaagt 10320 agcaatgtag cgaaagcagc aagataccga gaaatccatt gccatttaga cgattgtgaa 10380 gggcgtaaag gggcagctcc caaaggatac ttcgtatcca tacgtcgata agagagtcca 10440 agtatgacag caacgaagcc aaaaattgca ggccatgggg gctcaaattt ccaacttttg 10500 agattgaccg tcagaagtgg tagctttgca tcttgcacaa tttgttcagc caaataagta 10560 aacacaaacc ctaatccaaa tataacacaa agcttacaaa aaaaagttat taaagatgaa 10620 tagtctataa atgttatccc tttctttctc tgtttcttta aatcatcatc gatctgtcta 10680 gacgcgtaat cttcataact actcagggat tcatcatctt ctgcctgctc ttcatctaat 10740 ttaagtggag caaaaagccc tgatagtgtc gatttcatat tgtccaaaga aagtaccgac 10800 aaggacttct tgaccgctcg atttccatta taaccatctg ggtagcgcgg acggggttcg 10860 taaatctctt ttctgctcat tttattcaag cttacggcac ctttctgtag agatccttgt 10920 gaaactgact aaatggatgg agaagaatca atctttacgt ttaggtactt ggcagaatcg 10980 agacattgca caaaacacgc atagcccagt gacaagtaac aattttgagt aacaaagatc 11040 tcaagtaaga gagatctgaa atgaataaat atttacaatc acttttatat gtgaatttga 11100 cctttctaaa ttatagaaat atactcaaaa cttttctgca tccatattac tcttattgtt 11160 aaggtatatt gtgctttgat cacttgaaga tgcatgccat aagtaatgac aatgttaact 11220 aataacgaaa atatccaagg aaaaaactct cgcaaacact cattctacga aacaatcagc 11280 cacgaagaaa ttgctttaaa taattaagga aatttcataa ttgagtctgt atgcctaaag 11340 tggtttctct agtttattca aagtatagca aattcatcta ctatttttaa aaccgcaaaa 11400 caaaaatatt aattgaatag aatacaaaaa gcaaaacaaa gttatgctga ctacatgatg 11460 ccaacaactt tcaccttccg tagagaatca tcataaagaa aaaacaatat tatggttata 11520 aagtttgtct catcacaaga aataaattct tcagtccaaa aaactattta atagacttca 11580 atatattaaa aaacaaagat cattctaacc atttggacac ctaaggaatt gcgctgaaag 11640 gtaaaaatgt caccaaacta tacttatcaa gaaccattta tgacaataat tttcttctaa 11700 attaagtgtg agatgtatca attatgaaag aaagaaataa attgaaactt cttcagctta 11760 ttcaccttaa gaagaggttt ataactgttt gcgtcgagga ctatcaaaag cgtgatagct 11820 gatttgaata gaggaaagta aacggcaaga aataaacaaa gttggaacca atacagccaa 11880 tgccaaataa cccatgtaca aaccaggagt aaaaaattga tattcggtaa acagtcccgt 11940 cgcaccattg tcggtgacag ggtgcttcct tgtttggtgc atagcaagcg tggtttgtga 12000 tccctcattt tgatcaggta aagaagccaa ttggccgtgt tgaagagcac tcttccctga 12060 gttgagacca cctagcgttt gaattacaaa ttcagcattg gcctcttctt cgttagcatc 12120 aaccttaaat ccttcaaaat ctgagttatt caaaggagaa gaggctataa ttacattcca 12180 ctgagcatct tgttccaagg tagattgtaa gttgtagaac atttcatcca attccattaa 12240 ttgtgcactt ctatgataac tttcatttga cagttcattc atgtaaacaa cagttatgcg 12300 atcattttga agaggaggaa aagcattaaa ggatccaccc aagtaaacta cctcaacgtc 12360 gcagttttgc tttgccgaat gcaccaactc ttgtgagtcc aaagactcct tggaataagg 12420 aagaagtaag ctatagggtg attgcaaaga aacacgcttt aaatgtttaa aagctcccaa 12480 ctgaaaatca ttaacctcaa ggcctggttg atgtataatt aaggtagctg tattgcatgt 12540 cgaaagtgcc tcaattgcgg cgtcaaaaaa catcataggg caagtggata ttgaagaatc 12600 atcggatgat ttggggagtt tgctgttttt agttagatta aataatttac acagtataat 12660 gccatcgatg gatgcaggac atacgagttc gtagaaaata agaaaatcgg cgaagtatct 12720 ttaaatgctg atactaaaga aaagcaaact ataaataaaa tactccaaga aaacattttg 12780 acactaaatt ttctttactt tggacaagtt tggatgttgt caattgcttg agcgttggag 12840 tggtagagaa tagctctata tactactttc agtatctaaa ggtactaaaa tccttctgaa 12900 tgaacaagct acatataagc agatagatta tgtaaatata acatgttatt tacgagaaaa 12960 aaataatact acaaaacaca agacggtgta gattttgttc caaaatcatg acaatagtcc 13020 atgacacttg ttatacacaa aaacccttat ttattactca gtccaaaata cccgtttata 13080 aaagacgtgc ccttgtaaat cccttttgct ttcagccact caaagctttt tcacataact 13140 aattaacatc gaaggaaaga aatgtatcag aaatttgaaa caggcaaagt caaatggtgt 13200 ttataaatac attgtcaaaa ctctttcttc tagccttagt agaaaaatgg taattatttt 13260 aaaatacttt tttttttcaa tttaggaaag cgaaagtcag tttcacttat tccctttgcc 13320 ttctccagaa gaaccccgtt tttgagcacg cagttcactt ttcttaagag gtcttgcatc 13380 ttgaatgtgc acaatgtgtc ttttatgagc agcaagattg gtgtcactag tccaaattgg 13440 cagagaggca ctgtcagctg ttttaatcgc aacattatca attgcagacc accctttcgg 13500 aatgaaatta gttagcagac acttcaatac agtcgtaata ttctccaaca attgttcatt 13560 ggtttgagtg gccaaaccac agagaatggt atgactagtg ccggcagata acttaagata 13620 agtagaatga agacaacgag caacttgatt acgcaaagtc tctttctttt gtaaaacaga 13680 aataggaaat ggcttaattt ttttctgttc aaaaactttc cccatcaata gggggatgta 13740 ttttaataca cgatcatcaa ccaaaaaaag gttgtgagag tctcgtagct cacatttttc 13800 tcggattgtt ttatacttta atttcaatct cgggatgcta agtacttttg taatgacttc 13860 gtcaagccct tgttgctcca ccagatcttg atatgtctgc tgtgaatctt tcacaatcaa 13920 acaagcatct gttacatgca ttatcctgtg cggaaggaat ctgtaaaata gttagtacct 13980 tataatttta atgaagaaca cgcatcgatt ctatgaatgt tacaacaagc ttgatttatt 14040 agcaaatcaa caaaaccgta atacctcttt atttctgcac aagcagtaga agcttaaggt 14100 tttaagtaat tataagaaca aaaattttat tgttgatctt attacttcag gaaacttaat 14160 tcatcattaa tgctcactta cacttttgat ggtcttctaa gcgactcttt ctcaacgggt 14220 tggaatgtat taacctgaat ataaaccttt tctttttcaa taggtttatc agaggatcga 14280 atgtgctgca gcagggctct aattgttttc tctagctatt gattatttgt aagtaaattg 14340 cacgataatt tgaaattaaa aaaaaaattt cttactaatt ttatgtcaat tttatccaat 14400 gactttaaat ttttcttttt ttcacttgta atcgccattt ctattaagat gtaagtaatg 14460 gatggctttt tgcaagttca acttgggttg gtcagagaag ttaatattac aatgctattg 14520 aaagttctgt agcatatcat tatcaaagtt tagtttgtaa agaattaatc aaagaacaat 14580 tgttctgtct tatatgccat ggccttatta aattgatggc tttgaaacga tactagataa 14640 ataaggccaa caactcaaga accgcaaatg tcgaatgaat ggaaaactta ttatctatta 14700 cttgtttaac aattttcttt tagtggttat tgtaaatttg aatcatcgct tttcgcaaaa 14760 ctccgcatat tgaaaaccct catctattcg actgtaaaaa cggaattcaa tagatatgaa 14820 atttctatac aaccgcacat ataaaaggaa accttgtaac ataattttta cattcatacc 14880 tacactatga atgcagtata cagattactt tttgactaaa gtaaaagaaa taacacacac 14940 gaaagaagca agagaaaaca aacattcata aagaatatca tatcatttct gttattcata 15000 aaagattatg ctacaaattg ctcacccttc gtaatgctct ttttcagctc acccaaagct 15060 accttaagaa ggctctcctc ataatcattg attttaccaa cagggtgaat ggtgtcaacc 15120 ccatccttac ccaaagttac acgagaggca aagaaatcaa ttccttgatc cttgtacaga 15180 ggggactcca caaaggtgca ttcctcaacg ccagactcac cagccaaagc acggagtacg 15240 gaggaggcca tacgagcacc ggcataggcc atagacaagg tcgcacttcc agcaccagcc 15300 ttcgccttta caacctcatc accaccaaat tggatacggt gaataagtgc gtcacgcttt 15360 tcaccagtca attcaacacc gccttgggac aacaaaggta cgatggtcgc accggaatga 15420 ccgccaacaa caggaatatg aagaagttct gccttgccat tagtgacttg agaggtgaaa 15480 cggctggcac gaacagagtc aagtgtggtg acaccaaaca aatgtttggg ttgatgaacg 15540 ccaacacgtt ctaaagcctt tttaaagatg ggcacagtag agtttacggg gttagtgaca 15600 acgagatatt tggcttcggg acaagtttca cctgctgcaa aagcaaggtc ccgcacaatc 15660 gatgcgttag tagcaaagag atcatcacga gtcattccgg gcttacgggg aacaccagca 15720 ggaataatga ccacatcagc accgttcaag gctttttcaa gtcccttgtc atcaggagca 15780 tagccaacaa cattggaagt ggtattgata tgtccaatat cggcagcaac gccaggagct 15840 cccctaatat cgaacaaggc caattcacta accttatcgt tcagttttaa aagcattgac 15900 aaaggctggc caatacctcc tccagcaccc aaaacggcta ctttgaatgc gcgactggag 15960 gtcgtagaaa aagaacgggg agcgatactc ttaaggggag taaagttttt gaaagctact 16020 ttggcaaaca tctttgaaag gtacaaattc gcaaagcaaa gtagagaaca cgggtattta 16080 aaaaaaatag agagagtgtg tgtgagacag agaggggggt aaaagaaatt tcaatagaaa 16140 atgtccagtt gaaaggttga ttcttctttt cttcagaaga tactagacac tatatcaaaa 16200 gttagaaaaa tttgttgaaa ataaaatatg tatatatatg caaacatgag tagccgcatc 16260 ctacaccata acgtttatac ggactgacta gcaaagcaaa gctactcgac atcctggtta 16320 caaacaaact cctcatgccg attctaagca taaaaaagca tatgcgtata gcatctctta 16380 taaaatattc cttcagaaag tcctgtacct agtgacctcg gagaaacggg tacggtacat 16440 aaagactggc gtagctgttt atgtcaagac ttttttccaa aaaaaatatc gactttcgtg 16500 tgtataaaaa ggtctcaaga gtagtattta cgtcggttta ttcattttta aaatattttt 16560 tctggcaaat tgggatgtaa cttgatcgtt ttgcatactc acttttactt accttaaact 16620 taacaagttc gaggtacgct tttggaagtc gttttagata cttttaggca aggtcccgag 16680 ctttgttgat tatacgttga ctatttggaa gatatgttga agttgagaat cacacagtga 16740 gttggtacag tatatatacg aattgtgggg tagtgcttac actcaatata aggttgtagc 16800 attacgcaat cgatctcaac gggcattaaa gatcgaacgc cgatttgtca agaacgacga 16860 ctggctaaaa tagcaaaccg caggacagtg caaagcaatg cggaataaat tcctaaaact 16920 cgtatagtgg cttcttgcta cactactgta aatatttggc agaaagaaaa gctactgtac 16980 tatttcaact ctacaatgga aacagattat acaggcagct gtacaatgta agaatgaaag 17040 tgacagttgt aaagttatag ttcaagcctc aaagaaaaaa tattttgtat attatatata 17100 tgtatatatg tatatattta tagatgaact cattcaacta taaaacttcc aaaatcttcc 17160 tttcctcttt tattgaacag catggctttt tttcataaaa acataacatg agcaaaacag 17220 caatcgagaa aatgatacct tagctagagg atttgtttag actgaaaaac aaaaacaaaa 17280 agaagatgat gatgaattca attggcgaac ggaagacact taaaatcctt tcgagttaaa 17340 atcaacaggg aaaaagaaat gaggaagcgt catatacaac agccttatca ttgtcatcca 17400 taaattctat ttgcacacaa acaatcacta aatttaagct tctatatcgt ttaactcgta 17460 aaataaccac tattcgtatg tatgcatgca cgcatatatc ataaagtcaa cgtagcaatt 17520 cgtggtacgg acaacaactt ttcccgcgca ttatccgatc ccattcaata taaagatgta 17580 tgtggggaag tacacattga gtccaaggga tatttgggca aaaggtaaat cgcatcggaa 17640 agtcgaaagc gaagggaaaa caaatatttg tatctctgaa ataagccgaa gatttgattg 17700 atcaatttta caaaacatcg agcaaagtgt gtcgttagta gcagtaaaag aaaaagatga 17760 agatgaataa aaagctctag acaaatcaac ttaaatcttt actatgaaac cgttaggaat 17820 atagcttgaa aaagctctct gagaaaaact tattcgtgac gtacaatctc agagacaagc 17880 tctccctttt cattcacctt gtgcttgatc tgctcgggaa cagcacgttc agcataatct 17940 ccctcttcgt tggggacgtt gatgttcaag cttgttgatt tactagtgac aacttcggac 18000 gacaacgaag atttgctcaa atagatggaa cctccatcgc attggtcgat aacaatcatt 18060 ggaacgtgat tcataacttg gcagccaaaa ttggaacact tagcaatatc aaaagcggcc 18120 actaaagtat ctactacaac gctagtacgt ttacagttgc tcatggaaac ggtgtttaac 18180 tttcctttaa ttataattgt gcaattggag caaccgaaaa tttgcactga gtggttgagc 18240 tccacagaat ccaagactat actgtgattg tcgacttggt tttcaacaaa ccacttagta 18300 ttttccaact caatgcgagg tggtttaacg ggagcagttt ccgctggctt agaaggagca 18360 gagcttttga ttttaggctt aggaccagga gtgggtcccg ttttacgtaa attcggattt 18420 ttgtgggtca tttcactctt atccacctta cgaagtccgg atgtaattcc ctcgccttta 18480 ttaatttcgg caaacaccgc tcccatatca cctttattat cagcaggtgc gggctcgttg 18540 ctatccttcc aaaaatcatt agatggagga ggtggtggtg gtggtggagg caagccgccg 18600 tttgcagaat cgccagaaga tggtgcctga gttttcgaag cagacaagtt tgccaaagcc 18660 gttttcaagg gtactgcatc ctgtttagta gaccaggtga gaccggtttt gaagtgggtc 18720 ttgacgtatg taatcaattc agtcaacaga gtaaggtaag aacgaaccca ttcgatttgc 18780 aagtcatctt tacctttaaa ctctttcatt acacggttgg cgtagaattg ggacgaatct 18840 ttcatttcag acataaagga taatggagtg ggctcaactg tgacccagcc caaaatacta 18900 attccactca tgacggtaga aagttgattg aactcggggg cggtgcggtg ttcatctcga 18960 atattggtaa tagtgagcag ttcagattgg ataggcttga ggaattccaa gagttccggg 19020 gaatccatgt cgggtttctg ggctttcaaa gcgacgctca aaacctgacg taaaaggtta 19080 aaagccttct cgacgtgttc actttgttcg gcaatcaaac caccaatttt tttactcaat 19140 tccatgtatt tagataaata cttggaacaa aattcatcgt aggcggaaat ggaagcagga 19200 accgcttcaa cggcagaggt ggatgtaaga cttctgttcc gaggactgat agcagccgca 19260 acttgatcat gtaatgatgc gacagcagga ctaccagtcg acacggttgg ggccgttgga 19320 gtaccaatgt tgaaggatat gttgtgggtt tgactgtttg aatctctaga aggacgatgc 19380 atgttgggaa gaggcttatg accactttcc acaagatcct ccaaacgaga agttgccgct 19440 tccagtctat atgagtaaat gttagatgca taatcaatta aagactatta ctcttttagc 19500 agtttaatgc aattacatac cgtttgagaa tcgtggtaaa attgtagcct gtttcacgta 19560 tattgatcat atccgacatg gttagacgaa aagaaaatgt gtttagcgga ggttaagtga 19620 tttttataat gcaacgcaac aaatatagta agtgtggtgg tggatggagg acgaaggaac 19680 atagagccgg cttaagcaat atgaaactcg gtatcgaaaa aagcgactta accttttcag 19740 ctgtagtata aactagcgtt tttattatat aaaaaattga aaaaacgata actatttccc 19800 tcttttgaag ctagaagagc tactggcaat gatcgtgtct tggctgtgaa caaacataaa 19860 tacttaacat aaaaaaataa ttccatattc gcgctgcacc ttactttagc caaaaaaaat 19920 gtaattatta aatgcaccga acctctgctg agatgagtcc agagattatc gaggtaaggt 19980 ttttaatctg gcagcttcgt ctgttgtgca atcgaaacta tatacgcttt ctgagttaaa 20040 agattggaaa agagaagcag cgatgccgtt gctgagcttt taatttttga cgtgctgttt 20100 acagtcgcta aacttttgac gaagttcaat ccttttccta catatcccta tgcttactct 20160 aagtatagtc tcattgttga aatgttaatg cctcaatttt ttaaaaagaa tttgtttacg 20220 atgaaagtga aggaatgcag ttatttaaac gactataata acattgcctg tacagtattg 20280 gcaaataaga cctagcaaaa caacgttgaa aattatgttg atttataatt taggagtaaa 20340 ttgattttac taagtcattt tacattaatc atacttttat ttattaattt aaatggctgc 20400 tggcaaataa ggcggtacac acgcatttgt aattttgctg tactgcgtta atgtcttgaa 20460 ccctataacg tttaaggaaa gctaagttgg ggtgaataaa aagggcagtg acaaaataaa 20520 tgtgtcagaa gcaattgcat tttgaaaatg agttttggaa ttctactttt cacttgctat 20580 tattgaaaaa acagtttgct ttgaaacgag tattgctcat ttatttatgt tgagcggcgg 20640 gaactgaact ccagagtgaa tattcttgat ttcgctgttt cgtttgtcgc aatcacagca 20700 attaattcgc gcatgtgttt tattaaataa agaattatct tgatgaaatg aagaataatt 20760 acacttcctt gaaaagtcct ctagatgaag aagatgaatt gaagacagat catgaaatcg 20820 atttggaaaa aggcctgctt ccagaatata attcagagga agagggcgca ttacctccat 20880 attcaggtaa gaattgtaaa taataagaaa ggaattactc aattgaaagt tgaaacttgc 20940 cattgctgta aaataacttg gatgtgatca ttgtttatag tcggccatgc atgcacacac 21000 tttgatacat gcactttctt tactaaagta tttcaatcat attaatttaa acagattacg 21060 cacgtgtaag caatcctcct aacatacata gagaaaacca ttcttccggg acgacagatg 21120 attcttcccc ttttttgatt aaactactaa tatcattcac tccaatcgtt ctactcaatg 21180 ctctagcagt ttgttatcta aagtataaag acgctttctt taaaaattat ggtgcagcgg 21240 aatggacgtt atttggattt tggtgtcttg tttgcacttt ggctttaata ttcttgactt 21300 gtaagtgaga caatggggtt aatcttacct tcagtcacta actcattaga cttctatgaa 21360 aagggccaag gcagttaaag taactgtaaa tttcttggca caatgtgtaa aggtaactgc 21420 ggtcggcttg tacaactcaa gggaaaaatg ggtagtaata atttggctat tatgggtagt 21480 catttgctat acactttttc ttcgcgccaa attcggtaac ctgaacttat acaaggctct 21540 catctgttct acatgcagta tttcagctgc tttactttta tttttactat atggtatgtg 21600 aagttatgga gttaccatta ctgaccgcta acacgcagtt cgtcttccat tttggacact 21660 caagcatatg ctttttggtt tgtttcaaat gctgggtgta caaagttgtg tcgttattgt 21720 acagaaaggt ttgatgcatt catttgataa acatatcgac gggacaggct acgaaattga 21780 agccacttca ctctttgtta taggcaattt tcttttcttt tacgaaatgg gtttgttcaa 21840 tattcctgta atttattcta accgtatcag aatgtccagg tgctctcaaa aggatgccca 21900 aatttatcag gaatggtata gcttctttcc taggtatgtg tattcaacca actgtatgaa 21960 tgatttttta cttacccgac taggaggtat agcaaatgcg attggaggtg ccaacgataa 22020 taatgacatt cccttggaag aaacggaggc cgaaagcgaa gtctaattgc tttattaatg 22080 tagttgtcgc tacagttgga aaacctcttt accaaaatca ccaatgcaga gaagctgcgg 22140 cgttttttaa aaaattagca ccaactttct ttaatcatcc tctttcacta taagtttatg 22200 gaatatatgc ttaactcatt cttccaatta ctataaattg tcaaaccaat gcatcgcttg 22260 aaatgattcg cgatgttggt taacatacat tatgaaagcg atttatgaag tttacaataa 22320 tggttttatt attcaaaaaa aagagtttgc ttactggttg ttacatttaa ctattgcaat 22380 aaaaaaactc gccgtgctct ttcatattgc atttatgatt tggatcaaat atttgagcaa 22440 actgatttta gatcatatta tcagcttttc ctgatgtttc ctattcttgt taatgatcca 22500 ctttttttgc ctggggatat taataaatta gttagcgtta ggattcaatt taggtggatg 22560 aatgcgaatg tttacatctg gaaggttatt aagataagaa acaaaatgca caaggttgta 22620 acatacagtg gttggttgtt taaagccttt atatcttatc gacaacattg gccgattatt 22680 gcagaagggt gttacaattg aaactcttgc atgttctttc cttttttttt ttacgtgcaa 22740 tctttccaaa ttgcagtttc aattgtagat aatgaaaatt tgtttgtaaa aaagctccag 22800 tggattttat aaatttactg aagcaaggaa cttctttttt cccctactag ttgaaatata 22860 tcctctgaaa ggcaaaattt tacagcgtcc gttaaaccaa atacttaacc atagttgatg 22920 tattaattga tttccaactc attttttgtt tctacctttt tcaatactgg atgtcttcta 22980 tatgggtaat ttgaaattcc tgctattcga aaacaactat gttgctcaca cattatcctt 23040 tcaaaaatta ataaataata aatatttaat atataaatat agttccaagt cttttactat 23100 cctaatctat gaagaaagaa attgtagtta gtttaattgc ggcgccagcc tcacttccaa 23160 acattcatga agagagtgta gctgaatatc tagggggcag gtagttagta tgccatattc 23220 acatacatcc tcaagaattt taacaccaca tcacaattgt cccgcctttt gttttgatga 23280 gcagctgaat gaatggattt gaatcgatgc acttgtatcg cgactattca cttacacttg 23340 ttaattggag tgagttgcga tgatcaaagc tctttgtcca taatgcccaa ctaactagtg 23400 agactgaata ataataatat tgagatactt tatcatgttt tcatgatgtt tcttttctac 23460 atttgctata ttcagttcaa tccggccacc tttgaacata ttgccagcca tctgaattgt 23520 tttgttgaca ttaggctggt tgccctccga gtttgtttat ttacacggtg acgcaggctg 23580 gttgcgatga acattctcaa cgctgattgg ctgcttctcc agcttgccac tgtaaacaaa 23640 tgatgtcagg atcgtctaac gaacgaggct aaactcgtat atataaacat cgatctgctt 23700 ccccattgcg gtttgctata aaatctggtc tttgcatttt ggctgttttc cacttgaaaa 23760 catcttttgt ttacatcgtt tgtcttcctt ctcttaagtt actttgtaaa acgtcgtccc 23820 agtgtttggg tgcttcagtt tgacaaagct ccttgaagta gttgagttta ttatcattgt 23880 tcatctttcc tcctttttaa tcgatccaaa aagacttcat cgtctctaca tttttattcc 23940 atatattctt atcgtcctta cattttctat tcatctgata tccctttcgt tccattattt 24000 ccccctattt tcaattgcat tttccgttct caaaattatc gtctccaaaa attactttac 24060 gtactctcac attttaattt tataaaaaaa atgtttgcat ttgcctcttt tgcgatttcg 24120 gccatctttt tcctttgctc gttctcctat gtctcgtcca tcaagctttg tggcatacca 24180 ggtgctcctg cttgtaaaag gcgtgagatt tctttatata agcgtgcaac tgacacattt 24240 cctgacttga gttctgctat agcttctacc tcctattata atatttcgga aggtacatat 24300 tgccatgtaa gtggctccaa cctttgtgtt tcacccgatg taattgccat ttgcgctaat 24360 catagcactg ttctcttgaa ctgccctact gtgcttggtt atcccaaggg tcgtggttcc 24420 gcatgtgttg aaaccaattc ttcctacgga ctaactcgcg gtctttgtca gatcggatcc 24480 tccaactact ccactagcgc taattcttcc aactttgaca atgcaaatgt tatcaacgtg 24540 accacttccg ttagttcggg aagtacgagc actcacagca agcgttcttc cggtatatct 24600 ttaagctata ccaacattgt tgatcaaccc atcttattca ctcgtgattc ctcaatggat 24660 tggtcttgca acatgacttt gtgtaatacg gattaccctt acttggttaa cacttgcttc 24720 aatggcaccc aataccccgt taattgtaac tctgctttgc gcactccatt tggtggtgct 24780 acttgccgta atattggcta taaaggtcaa ggtatttgtg tatataccaa cgacagtcgt 24840 atccctgttg ccgatgacca tgttattgtt aacactactt ccaaaataaa tccaaacatt 24900 accagtgtct ttaactaccg tgacaatgcc ttcttgtggt aaaggatttc gcatagattc 24960 cctttttctt taaaaaaaat ctaaaataag gaacatgggc acttgttcct tacttgcatg 25020 tcttccttgc taacattaaa ttatcactta cctccttcct ttttcatgca ttccttgtcc 25080 gtttaccctc aacttcacca aagtgatagg cgtccagtaa gatttttatc ttttggcttt 25140 tgcctctact cttttctcaa catgtcttta tttgcactct tatatttgcg tgaggtattt 25200 acagatttgt atcttttttt ttttttttgc atgcattttt tgaacgagca aattaagtgg 25260 gacatactgg tatgttccac cattaaagcg catatatttt tgcaccaaaa taacttacta 25320 aactacattg cgtattttcc tgtgatcatg gcactttacc ttgatatgtt tgatcttcaa 25380 acaatcaatc ataagcttga ctgttcattt ctattttgat tccttttaat tcttcatccc 25440 tttctttgtt aaattaattt ccttt 25465 //