ID SPCC1753 standard; DNA; FUN; 13824 BP. XX AC AL035210; XX SV AL035210.2 XX DT 15-JAN-1999 (Rel. 58, Created) DT 28-MAR-2000 (Rel. 63, Last updated, Version 4) XX DE S.pombe chromosome III PCR product from region of cosmid c1753. XX KW git3; glucose-triggered adenylate cyclase activation protein; KW halotolerance protein; Inositol monophosphatase; KW meiotic recombination protein; rec7; replication factor-a protein 2; ssb2. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-13824 RA Lyne M., Rajandream M.A., Barrell B.G., Volckaert G.; RT ; RL Submitted (08-JAN-1999) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and Katholieke Universiteit Leuven, Laboratory of RL Gene Technology, Kardinaal Mercierlaan, 92 blok F, B-3001 Leuven, Belgium. XX DR GOA; O94505; O94505. DR GOA; O94744; O94744. DR GOA; P36625; P36625. DR GOA; Q92373; Q92373. DR SPTREMBL; O74428; O74428. DR SPTREMBL; O94506; O94506. DR SWISS-PROT; O94505; DPNP_SCHPO. DR SWISS-PROT; O94744; GIT3_SCHPO. DR SWISS-PROT; P36625; REC7_SCHPO. DR SWISS-PROT; Q92373; RFA2_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c1753 is overlapped at the 5' end by cosmid 584 and at the 3' CC end by cosmid 162, EMBL entry SPCC162, accession number ALO23860. XX FH Key Location/Qualifiers FH FT source 1..13824 FT /chromosome="III" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c1753" FT /map="IIIR" FT misc_feature 1..920 FT /note="nominal overlap with cosmid SPCC584, EM:AL032824 S. FT pombe chromosome 3" FT CDS join(complement(891..1016),complement(50..763)) FT /db_xref="GOA:Q92373" FT /db_xref="SWISS-PROT:Q92373" FT /label=ssb2 FT /note="SPCC1753.01c, len:279" FT /gene="ssb2" FT /gene="SPCC1753.01c" FT /product="replication factor-a protein 2" FT /gene="SPCC584.06c" FT /protein_id="CAA22775.1" FT /translation="MAYDAFGKPGYGPDFNSAFSPGMGGGAGFNEYDQSSQPSVDRQQG FT AGNKLRPVTIKQILNASQVHADAEFKIDGVEVGQVTFVGVLRNIHAQTTNTTYQIEDGT FT GMIEVRHWEHIDALSELATDTYVRVYGNIKIFSGKIYIASQYIRTIKDHNEVHFHFLEA FT IAVHLHFTQKANAVNGANAPGYGTSNALGYNNISSNGAANSLEQKLAEYSLTPAQMTVM FT QAIHSAPETNEGVHVRQLAQSVGPGIDLTAVTDFLQQEGIIYTTIDENHFKSVLQDQ" FT misc_feature complement(764..783) FT /note="ctaatttttccaatgtttag, splice branch and acceptor" FT intron complement(764..890) FT /note="confirmed by mRNA" FT misc_feature complement(885..890) FT /note="gtaagt, splice donor sequence" FT CDS complement(2283..3683) FT /db_xref="GOA:O94744" FT /db_xref="SWISS-PROT:O94744" FT /label=git3 FT /note="SPCC1753.02c, len:466" FT /gene="git3" FT /gene="SPCC1753.02c" FT /product="glucose-triggered adenylate cyclase activation p FT rotein git3p" FT /protein_id="CAA22776.1" FT /translation="MLHLDYTFNVSDATSTSSIIIVSRRELANLRIMVIIASAISIVFS FT LIAIFWRWSRRRTIREQFHIALFSVLFIRSIVQMIHPCLALSDPFFWAPKHRCFTIGFF FT LLVLVRMTDYWIFINILHNALLVLFPHVDTERRGLYRFRHTVFTLSFVIPLTIGGLAFT FT NKRNTFVNLQTRCYLPYTPVRFMFGLNWSFDYALSIAIIALQTCMFISIRRKIKRFKKY FT SHQQTNVFDTLNVIDSYPTAPDQVALPPFPDTNSTLTYTPSNSQSIYSSQSQPSPYSRP FT LLSSVHPNLPPGSQSTPANLNQSGIHFEQDFRDSPNRTNGLEDHTSFKLSSPLTSDEDG FT ASSVLAAYGNDMQDDPLLKQRKRILSQSKFLFAYPAIFIFMWILPQIQIIVILAQPLHC FT SGSCKRFAFVAVFADNFVAIFIALSDFIWICYRGYTYLKERDSSKSYWDQIKELTLKWW FT RGKFGEEK" FT misc_feature complement(5867..6282) FT /note="possible RNA gene as hits dbj|AU007386|AU007386 Schi FT zosaccharomyces pombe cDNA, clone spc01882 but no ORF in re FT gion" FT CDS join(complement(8019..8171),complement(7848..7961), FT complement(6990..7742)) FT /db_xref="GOA:P36625" FT /db_xref="SWISS-PROT:P36625" FT /label=rec7 FT /note="SPCC1753.03c, len:339" FT /gene="rec7" FT /gene="SPCC1753.03c" FT /product="meiotic recombination protein rec7" FT /protein_id="CAA22777.1" FT /translation="MNIFPIVKYSVAEDSYTTDSSHINWSHYSDGGFTLSLTSGLLQIR FT QHEELIQSINLLDLWHQLIPGTKEKCLTLLSRAPCMNIRAFTNNVMKRFQVKFPSDVHY FT MKAKVEFEKLGLVFKDAKSSSEKKQFNNSQSQSNNSQELSLMNNAYNKSSAQQPNLLLQ FT PSYIPMTQTATTAVNNSTNYVNPAPLQHVMPNAEIFSNTPPLKRFRGDAGMTQMPLRSD FT TSIESITASQQPTWDENVVITSSPFNPNRNAYSYGANSQYPIIAATPLNSQTQASWVAQ FT PENQAYANLIPSPPTTSQILPTELTEEEKQLRSKVLFYLKQDSFIQLCQSLERVWNKM" FT misc_feature complement(7743..7755) FT /note="ttaataaatttag, splice branch and acceptor" FT misc_feature complement(7842..7847) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(7962..7976) FT /note="ttaacaaacaaacag, splice branch and acceptor" FT misc_feature complement(8013..8018) FT /note="gtacgc, splice donor sequence" FT CDS 9106..10167 FT /db_xref="GOA:O94505" FT /db_xref="SWISS-PROT:O94505" FT /label=SPCC1753.04 FT /note="SPCC1753.04, len:353, SIMILARITY:Saccharomyces FT cerevisiae, YOL064C, HAL2_YEAST, halotolerance protein FT hal2, (35 7 aa), fasta scores: opt: 838, E():0, (43.6% FT identity in 34 2 aa)" FT /gene="SPCC1753.04" FT /product="halotolerance protein homolog; putative inositol FT metabolism" FT /protein_id="CAA22778.1" FT /translation="MSFDAEKQLAIAAVRRASYLTEKVFNQLIKEKSAAGALTKDDKSP FT VTIGDFGAQAIVISMLKDAFPNDPIVGEEDSDFLRENTQTCSRVWELVQETIQHATEYK FT ELGQIKSAEEMMSIIDQGSYHGGRNGRMWTLDPIDGTKGFLRGAQYAICLALIENGKPV FT VSAIGCPNLPYDFNQPETSPKGIIMSAVRNHGCFQYSLHNEKLEPVQVHMQDVQNTKDS FT KFCEGVEAGHSMQGTQEEIAKYLGITRGPTKMDSQAKYASLARGDGDIYLRLPTKMTFE FT EKIWDHAGGSLLVEEAGGVVSDMFGKPLDFGVGRTLKNNNGVIAAYKGIFEKVIEATAA FT VTSKDPHFQKVAQ" FT misc_feature 9457..9621 FT /note="Match to PF00459 inositol_P, Inositol FT monophosphatase family Score 54.44" FT misc_feature 9502..9543 FT /note="PS00629 Inositol monophosphatase family signature 1" FT misc_feature 9865..10014 FT /note="Match to PF00459 inositol_P, Inositol FT monophosphatase family Score 54.09" FT misc_feature 9958..10002 FT /note="PS00630 Inositol monophosphatase family signature 2" FT CDS 10796..11686 FT /db_xref="SPTREMBL:O94506" FT /label=SPCC1753.05 FT /note="SPCC1753.05, len:296" FT /gene="SPCC1753.05" FT /product="hypothetical protein" FT /protein_id="CAA22779.1" FT /translation="MSFPTDMETNEILDQLDKIDERNEDILLKSLKASKCTYKPWSREE FT FLRRLLTYRSRWAYVNDPQIGEINCCLNGWLCESNNILVCDVCRNKINLTALQQVDAEN FT DSLNELPEKTKERLEVSLKEEHQDNCLWRLHKFPPDIYHLSVSAELVQVGRRFNSLSTR FT LVSTHLPEEMTLKRLEKVANKIRVDWEKEDAAVLLGIALTGWSEQVPGRLYVCNYCHRR FT LGVWNLQSEGQDFDVLEEHKKSCPWVIPQPFTDLLGWQQIFELLCKESIFQSTTKTMDV FT SQYTDYTFSLLQGLR" FT CDS join(complement(12550..13297),complement(11883..12490)) FT /db_xref="SPTREMBL:O74428" FT /label=SPCC1753.06c FT /note="SPCC1753.06c, len:451" FT /gene="SPCC1753.06c" FT /product="hypothetical protein" FT /gene="SPCC162.12" FT /protein_id="CAA22780.1" FT /translation="MERPSLSRRTSSSTVSTDGEGVYSRSTKERKRNFIVNSRLKRGGG FT HVRVNRSGRLGSVTMRPSALTRAHSQNPNSSLVNNSSAVSHLTKQRSLNDLHELNGPKH FT VAKNGLIPLTQRKPNCVWDDAPVDNDSTAGNLDSDSALPTPSVTTNEAADSSRASSPVT FT RVVAVHDNKKKIINSNISNAPPFNNTDVQASARPPAAGQDDSAADASTTKSSPVHNEVM FT AEPLPHSNNREVTQATNQPKWQIHSGSDIASEPPTLSRGNSLSLLANRKVPSTNVKKSQ FT AELYDLGSSTSRTQQKLLIQRASSKFDIVEDDMDTNPSKRFSNPHTKHIMDLVRTQYRN FT VLRTRELIPEFLEKIRSSYSNNQNFDSQNAFNTSAAGTAGTREETISNGQNGIVASAET FT SKKDDGVQSASLNASMSARSHARQRSIHVPKTRKDTDYESIHQKLLQLWSQG" FT misc_feature 12195..13824 FT /note="nominal overlap with cosmid SPCC162, EM:AL023860 S. FT pombe chromosome 3" FT misc_feature complement(12491..12505) FT /note="ttaacttacttttag, splice branch and acceptor" FT misc_feature complement(12544..12549) FT /note="gtaagt, splice donor sequence" XX SQ Sequence 13824 BP; 4528 A; 2360 C; 2703 G; 4233 T; 0 other; aacctcgaaa cgcaatacca aaatcattat ttcaaaatca taaaaagcgt tattggtctt 60 gtaaaacact tttaaaatga ttttcatcaa ttgttgtgta gatgattcct tcttgttgaa 120 gaaaatcagt aaccgccgta aggtctatac cgggacccac gctttgagca agttgtctaa 180 cgtgaacacc ttcattcgtc tctggtgcac tatggatagc ttgcataacg gtcatttgtg 240 cgggggttag tgaatattca gctagttttt gttccagaga gttggcagca ccatttgaag 300 aaatgttatt gtagcctagt gcgttggaag ttccgtagcc tggagcgttg gctccgttca 360 cagcatttgc tttctgagtg aaatgtaggt gtacagcaat tgcttcaagg aaatgaaaat 420 ggacttcatt atggtcttta attgtacgga tgtattgaga agcaatgtaa atttttccag 480 aaaatatttt gatgtttcca tacacacgaa cataggtgtc tgtagcaagt tcagatagcg 540 catcaatgtg ttcccaatgc cttacttcaa tcattcctgt tccatcttct atttgatatg 600 ttgtgtttgt agtttgagcg tgaatgttcc gtaaaactcc tacaaaagta acctgtccga 660 cttcaacgcc atctatcttg aattctgcat cagcgtgaac ttgagaggca ttgagaattt 720 gcttaatggt aacaggacgt aatttatttc cagctccttg ttgctaaaca ttggaaaaat 780 tagtattaga tatttttatg aataaggtca gtgctagtac aaaactatca accaaaaagt 840 atcaccttgc ggttattcaa acaatagttt tagtatttta tcccacttac tctatcgacg 900 ctgggctggc tcgattgatc atattcatta aatccagcgc ctcctcccat tcctggagaa 960 aaagcgctat tgaagtcggg accatagccc ggcttgccaa aagcatcata agccatgagc 1020 acgtattatc tcaaattatg aaagtttgtt agggtgaatt aaagagcgat gaaaaagcaa 1080 atcaaccact taaaaatata tctgcgatct tttagagagt gatttttaaa taattgaata 1140 taaagttaca gctgattcca cgagtagtct acttttcagt ggtgtgttta gtacaagtta 1200 cgagtcgcgt ttcgcggtgg tgtaccgaaa agaataaaat caagcaagcg tgcttatata 1260 ctacaatgta ataaaattaa ctgttttatt tagaaaacca tcttacatct actttttttc 1320 tctataaccg tatagttttc aatacaaaaa cctactaatc acgggatgct caattgactt 1380 aaaacgctta aagcaatcag atactgtgct accattctgc tttaccaaat gtaaagaaaa 1440 actaaaaaat acattattaa atttgtaaac attaacacat tcatatgtaa caagaaggca 1500 tggaacaaat gtccgacgca attttacaaa tcgtatagga agaaaagcga tttatccaca 1560 acaaaagaat agctaatggt gaatgactat tcgcacatcg acatatacaa aataagaaca 1620 taaacgtatt gctatgcaca atccatccat tttatgtatt gaggaaatat agtattgggg 1680 acataaattt tgaatatagt tttgaagaca gatgcttaat gcaagcagta aaatgtaaga 1740 gcatctgaaa aatgaaaacg agtgaatgat agttggtaaa gctgaacata aacattctat 1800 ataaggaaga attgtttagg cgactaagcg ttccaaaaat gaattccccg agatgaatag 1860 aaaactgtca tagacacagt acatatatat acatcgataa ttgtgagcgg ccttatcaat 1920 ttgaagcagc caagctttaa accatcttcc aatccgagcc ttttgccaag ttaagtagtg 1980 ccaaaattta atacttcgaa ataaattctg ggaagcgaaa attaaagtat gacatatatt 2040 agaggtgatg caaaaatggg agatattaaa atattagttg gtttaccaca gttgtttcca 2100 ttcacattcc attgtcattc actggatggc tttaacaaaa aaggaagaca tatgaatgca 2160 aaggctatga gaaaatttta agaagtaaag tgataataaa atcgtcataa aaagaaatta 2220 taatacaaga agaggagctt gtgagacttc accataaaca aaaataaaaa gaacaaatcc 2280 ttctattttt cctcaccaaa tttaccccgc caccatttta aagtcaactc ctttatttga 2340 tcccaataac ttttactcga atctctttcc ttcaaatacg tgtagccacg ataacaaatc 2400 caaataaaat ctgacaaggc aataaagatg gcaacgaagt tgtctgcaaa gactgcaaca 2460 aatgcgaatc gtttgcatga accagagcag tgcaacggtt gggcaagtat aacgataatc 2520 tgtatttgag ggagaatcca cataaagata aaaattgcag gataagcaaa caaaaactta 2580 gactgactta aaatgcgttt ccgttgttta aggaggggat catcttgcat atcatttcca 2640 tatgcagcca aaacactaga agcaccatct tcgtcactag tcaatggact actgagttta 2700 aaactcgtgt gatcttcaag gccatttgtg cgatttggac tatccctaaa atcctgttcg 2760 aaatgtattc ctgattgatt tagattagca ggagtagact gcgaaccagg aggcaaatta 2820 ggatgcacag aggatagtaa cggtctcgaa tagggagaag gttgagactg cgaggagtaa 2880 atggattgag aattagatgg agtatatgtt aaagtactgt tggtgtcggg aaatggtgga 2940 agagctactt gatccggagc ggtaggatac gaatcaatga catttaaagt atcaaacaca 3000 tttgtttgtt gatgtgagta tttcttgaaa cgtttgattt tccttctgat cgagatgaac 3060 atgcaagttt gtaaagcaat aattgcaata cttagcgcat aatcaaatga ccaattcaaa 3120 ccaaacatga atcgtacagg ggtataggga aggtagcatc gggtttgtaa attgacaaat 3180 gtatttcttt tattggtaaa agcaagtccg ccaatagtta aaggaattac aaatgacagt 3240 gtaaacacag tatgccgaaa acgatataga ccccttcgtt cagtatcaac atgggggaaa 3300 agcaccaaaa gagcattatg caatatgttg ataaaaatcc aataatcagt catccgaaca 3360 agtaccaaaa gaaaaaatcc aattgtaaag catcgatgtt ttggagccca aaaaaaagga 3420 tcgcttaatg ctagacatgg atgaatcatt tgcacaatgg aacgaataaa caatacagaa 3480 aaaagagcga tatgaaattg ttcacgtatt gttcgccgac gagaccatcg ccagaagata 3540 gcaattaagc tgaaaacgat agatatggct gaagctataa tgaccatgat tctcaggtta 3600 gctaactctc tgcgagagac aatgatgatg gaactcgtac tcgtggcatc ggaaacatta 3660 aacgtataat ctaaatgaag catgagcaac cttgttcctt attacaaagt ttaaacttct 3720 cttcaagaag acaggaaaaa aaaagagagg agaggaggtg agaaagtaaa aaacaagaaa 3780 agcaatatca gaacgaaaaa caaaaaaaaa gacaaaaaaa aaaggaatac tccaaagaca 3840 aatctatgac ttcagaaatg ttcaaataga caaacaagaa agcaaaacag aattttcagc 3900 cacttgggta atcagtccta ttacccttaa gaagtgcaaa aaatagtata tctcgtatat 3960 ccaattaccc aagattgcat atctgaccct cgattttcta taaattgctt cgttcgcgaa 4020 tataaacagt ctcttcaagt tgatgtaaaa aacttagcaa actggcaata tagaaggagc 4080 tctctaaact aaacgagttt gtttcgaata tgaatttgaa ttcccgtact tttatttttg 4140 tttctgtttt cttttttcca aaaacaagct tctcgtcttt acttttcaat taactcaact 4200 attctttcga aagttgtaga cacacgatta aactgttaaa ggtaaaagtt gaaatagtaa 4260 atctactgct ttttccttta atcgtggccg acgaagcagc tcaaaagtga taaacgaatg 4320 caaccaggaa agccggacgc aaaacggtgc cgacgattat taataaagcg cagtcccgtc 4380 tcgacactct tggcaagaag aaaagcgcaa ttgacgtgaa caaccaacga tgtattgtgc 4440 ttataaagaa agcactagtg aagtcactta gagctcaaag ccacttatgc acgttttgca 4500 aggctcttaa tagcgtggcg aaccttctta aggatattga agaataggga aatcggaggc 4560 ggtatggctt gcaattaacg ccgtacagtg aataaagcgg tactaaatca aatcggtgaa 4620 atttaccgat aattaaggaa aagacaaatc aattgaaggc gccgtggttt gggttggctg 4680 atggagttgg cttgattata agtaatgatg gcggagagtt gccgcctttg ctgttgtgta 4740 tgagtgtgta gtgaatatgc acaaatatac ctcaacgact aatggataag gtgttatagc 4800 aagtacagta gttaagtacc aatgcgggat ttttctgaaa aaatatgcaa gcacacgggc 4860 ttgacagaaa cacaagagga gacaaataaa ccaaagtctc cgcaccttaa gtccacagaa 4920 gaagaataaa aaaaaagatc gcaattgaat tatgtgaggg ggcccaggcg tcaatagtac 4980 agagtcgatt gactaagtag atttaagatc acaagctgta gagcaaatca gaaatttgca 5040 cctacgcaga gacaatgaac aattgtaatt tcagaaaaaa aaatatcgac aacgattcaa 5100 attccgagta attttctagc aagactattg aagaaaaaat ttccctaatc ccttgatgag 5160 ccttgtcgca ctaacacaat atcggcgatg ctttcacact cctagatgtg ctaccaccaa 5220 ccattataac ttatgaaaaa aatttgtagt atcgctgtaa acgaaatttt tgtgtaagaa 5280 tgacgagagt tgtttttgca cagacaaacg aggttcggac gatcggccta ttttttaagt 5340 acgatagtga ttagtatagt atatcgtgag gagcaaatac aatcgcataa aaaaaatcag 5400 ggtgaaaaga atcatttcag agtgcgttaa tgagaaagtc ctcgttataa aagaaaaaaa 5460 ggaaccgatg atttaaagtt attgatggtt ttaaaaaaca gcgtttattt ttacagtgtt 5520 taaagtcaag tcaatattag gcacaagaag aggtcacact ttattttcaa aagaaaatgg 5580 atgaaatgca actccatgcg ttgcgataag cgttaaacac caatctagga agcagtccct 5640 caacagaaat gaagcgaaaa tcgaatgatg gtgagaatag aataataaaa cgagccccgg 5700 taaattgaaa gttgatagaa tcaagtttca attaggggta atgaaaacgt gcttaaaaat 5760 agggagtaat gttgtagtta ccaaaatgaa caattcggac cagaccaata aatattgtcg 5820 aaataaaaca aggagtgtta aattttatta ttatgtcttt attctccttg gaaaccggtt 5880 cgtccacgtg aagagaattc tattagcatt gtcgaaaccg tttgatccgg ttatgccttc 5940 atatctttga aaacatttcc gccaattcca ccaagtgaaa atcacaatat cgttagtcgg 6000 tattgtcttt aggtttacta gcgggggcgt ttttgttttg aggaaaaaag aatattctct 6060 ggtttccatc taccttaagt gccgattagg cagataagct agattaagtg aaatgggaaa 6120 cgggattcat tttccattga caacactttt aaacattatt tgataattcg catgcaaccc 6180 ttcaaagtcg attcgacatt ttaaggttta cttcacggac attgaaatca ttgtgaagct 6240 ttgtagactg ttgtctctct cggaagtacc caaaaaaaaa aaaaaaatcc tttttacact 6300 cataacgttc tagctgtttc atccctttaa aaaatatcat gttttttttt tggtgctcgg 6360 aacatttact ttctccactt ggttcgtcta tttttgaagt taaactaact atttgaccat 6420 tttcgtactt aatgtcatga actcctctcg tggattgtta agtcaattat caaaaccaac 6480 caccaactca attttaaccg ttgtaacctg acccattatt aacactagta ttcatgctgt 6540 acttgcggca attcccccat caaaaagttt tcagagttgt cttttgatac cgattatgtg 6600 tcgtggtgga ggcttacacc ccaaggatcg gaacgggatc ttctcaattt gattttaatg 6660 ctctgcatgg acaagcctaa gggaaaagag tcatgcaaca agtagagaaa tttatttcaa 6720 cattgttgtg ttggcggttt ctgtttgcta atcctcagca acgatcatat gcagttgaga 6780 tctcgaccaa cttttcgtta aataatgtca aaatttgcaa caaatgtttt atcacggtac 6840 tcgaagaatg tgaacttaat gaagtttctc atttggttgc caaattgtgg tcacacatca 6900 attttgtcga aataaccatt ccgatcctga tttcgttcca tttttactac ttttttaaat 6960 ttgggattaa gttgaattgg tctgtcttcc tacatcttgt tccatacccg ttccaaactt 7020 tgacataatt ggatgaagct gtcttgtttt agatagaata ataccttgga gcgtaattgc 7080 ttttcctctt cagtaagttc tgttggtagg atttgtgaag tcgttggggg tgatggaatc 7140 aaatttgcgt atgcttggtt ctccggttga gcaacccacg aagcctgtgt ctgagagttc 7200 agcggcgtag cagcaataat ggggtattgt gagtttgcac cgtaagagta ggcattacga 7260 ttgggattaa aaggtgatga agttatcacc acgttttcat cccaagtggg ttgttgtgac 7320 gcagtaatac tttcaattga tgtatcactt cgaaggggca tttgggtcat gcccgcatcc 7380 ccgcggaatc gcttaagcgg tggtgtattg gagaagattt cagcatttgg catgacatgc 7440 tgcagtggtg ctggattgac atagtttgtg ctattgttca cagcagttgt tgctgtttgg 7500 gtcatgggga tataactcgg ttgtaataaa agatttggct gttgcgccga tgacttgtta 7560 tatgcattgt tcatcaacga aagttcctgt gagttattag attgactttg ggagttattg 7620 aattgcttct tctcagagga agactttgca tctttgaaca ccaggcctag cttctcaaat 7680 tcaactttgg ctttcatata atgcacgtca gatgggaatt tcacttgaaa tcttttcatc 7740 acctaaattt attaacaaca aaatacgctt catcaacact ccattttttt ttttaaaaaa 7800 agaggcctca atgtgatttt gaataaatct gcttttgttt tacttacatt attagtgaaa 7860 gcacgaatat tcatacacgg agcgcgtgaa agcagagtta gacatttttc cttcgttccc 7920 ggtatcaatt ggtgccagag atctaacaag tttatacttt gctgtttgtt tgttaaaaat 7980 attgaatttt tctagcaata tggtttcatg tcgcgtacaa ttaattcttc gtgttgacga 8040 atttgaagca atccagacgt taatgagagt gtaaaacctc catctgaata atgtgaccag 8100 ttgatatggg aggaatctgt agtatacgaa tcctcagcta cagagtactt aacaattggg 8160 aaaatgttca tgtttgttta tgtttgaata tgagaagacg cgttagactg aacctcattt 8220 atctgataac gcagtacgtt ccgtcacggt gtattacttt tgtttacatt tatgagttga 8280 cctgaaaacg actagacttt atggaatgta agtcttgtta tcacaatata ttacatatga 8340 ttgtaatttg ccataaggaa actatttctt caatctgtat tgaggaatat ctgattgttc 8400 attaatttct caagtctctt caaacaacag tattttgaga gaaaggaaat tttatgagca 8460 gtttcttctt ttactaatca atccctttaa aatattttta tgccttcatt tcatccttgg 8520 tatctacact tatataaaaa ttttaggcat atttgcctgt taaagggaaa cgcaagatac 8580 ggacttgcac tgcttttaaa ttatgcgttt tttccatcag aatgatattt tttttcctta 8640 atattatatt tcatcctttc tccataggtt ggaagggttg gcgaactgct ttgccaatac 8700 ccagacttta gtagtgtcgt ttgtataatt aatgaaaacc taaaatgtgg acatggagaa 8760 acctgtttta aaatattaac atgctctttt cacaatagaa actacataat cattattgtt 8820 taataaaagt tagcataacc tgcgatttta caaaaaaaaa aggtctttta gtcagaaaaa 8880 atgaaactct ttctcgtttc ataacaattt tttagttctt tcttctattt gaacaatatt 8940 tttggttaaa tgtggaaacg tcaattaaac accgtatatg ctgatttcat attcttcgca 9000 cttccactgc ccaggtttac aaaaatttcc aaactccgtg ttaacaggaa atttggtgct 9060 aaaatcatac ctccattaat aaataacatt agaaaattat ttaccatgag ctttgatgcc 9120 gaaaaacaat tagctattgc tgctgtgcgc agagctagct atttgaccga aaaagtgttt 9180 aatcaactta tcaaggagaa gagtgctgct ggggcactta ctaaagatga taaatcacct 9240 gtgactattg gcgattttgg tgctcaagct atcgtaatct ctatgttaaa agatgcattt 9300 cccaatgatc caattgttgg cgaagaggat tccgactttt tgagagaaaa cacccaaacc 9360 tgctctcgtg tttgggaatt agttcaagaa actatccaac atgctactga atacaaagag 9420 cttggtcaaa tcaagtcagc tgaagaaatg atgagcatta ttgaccaagg atcatatcac 9480 ggtggtcgca atggtcgtat gtggactttg gatcccattg atggaactaa aggatttcta 9540 cgtggtgccc agtatgctat ttgtttagct ttgattgaga atggaaaacc tgtggtaagt 9600 gccattggat gccctaatct tccatatgac tttaatcagc ccgagacaag tcccaaaggt 9660 atcataatgt ccgctgttcg taaccatggt tgcttccagt attctctcca taacgaaaaa 9720 ttagaaccag ttcaagtgca catgcaagat gttcaaaaca ccaaggattc aaaattttgc 9780 gaaggagtag aggctggtca ttcaatgcaa ggaactcaag aagaaattgc aaagtactta 9840 gggattactc gtggacctac caagatggat tctcaagcca aatacgctag tcttgctcgt 9900 ggtgatggtg acatctacct tcgtttacca accaaaatga catttgaaga aaaaatttgg 9960 gatcatgctg gtggttctct tcttgttgaa gaggctggtg gtgttgtttc tgatatgttt 10020 ggcaaacctt tggactttgg tgtaggaaga actcttaaga acaataacgg tgttatagcc 10080 gcctacaaag gtatttttga aaaggtaatt gaagctactg cagctgtaac atctaaagac 10140 cctcactttc aaaaggtcgc ccaataatct gtccgaaata ttctagcttt agggctttat 10200 ttagattttt cagcatgtta gcatatgcgt tatcgaggat tctacaaaaa atgtaatctt 10260 gaaaatattt acttgccata agcttatgat tagctccttt taattagatc aaaacaatta 10320 acaacatgtt atatgtcttt atggatgaca tattttattt accttaaatt atggattata 10380 tagtagcaat gtttaattgt tcaggtatag ttacacaggt cagtatgaat aggttaattg 10440 tatagttatt ttccatatta ccttactatt ttacttttag tattctcgta aatttactat 10500 acggtggtgt tgatcaattt caaggaattt atgccttcaa gtgtggtttg gctaataaca 10560 tggacatgtt ttcttaaaac ggtaaaactt tttaacaatt ttgatgaaac gaatattgag 10620 ctcatgatcc aaattggtat tttgagatcc ttcctaagta ctttgacttg cgctaccttg 10680 attcctgctg aaaacgtttg gaaaaggcat gtaataaaag ttttctatga taatatttga 10740 gacaccacat ttttcgaaaa gaaatataat tttttaactc ttagaacggg tgataatgtc 10800 atttcctacc gatatggaga caaatgaaat tttggatcag ttagacaaaa ttgacgaaag 10860 aaatgaagat attcttttaa agtctctaaa agcttctaaa tgcacatata agccctggag 10920 cagagaagag tttttgagac gattgttgac ttatagaagt cggtgggctt atgtaaacga 10980 tcctcaaatt ggtgagataa actgctgcct taatgggtgg ctttgtgaat ccaataacat 11040 tttagtttgc gatgtttgta ggaataaaat taatttaact gctttacagc aagttgatgc 11100 agagaacgat tcgcttaatg aattaccaga aaaaactaag gaacggttgg aagtatcttt 11160 gaaagaggaa caccaagaca attgcttatg gagactacat aaatttcctc cagacattta 11220 tcatttatca gtatctgccg aactggttca ggtcggacga cggtttaaca gtctgtccac 11280 tcgcttggta tctacgcatc ttcctgaaga gatgacctta aaacgtcttg aaaaggttgc 11340 aaataaaatt cgtgttgatt gggagaaaga ggacgctgct gttttgcttg gcatcgcatt 11400 gactggatgg agtgagcaag ttcctggtcg tttgtatgtg tgtaactact gtcacagacg 11460 tttgggtgtt tggaatttac aaagtgaagg acaagatttc gacgtattgg aagaacataa 11520 aaaaagctgt ccatgggtaa tccctcaacc ctttactgac ttacttggtt ggcaacaaat 11580 ttttgaactt ctgtgcaaag aatccatatt ccaaagtaca acaaaaacta tggatgtttc 11640 acagtataca gattacacat ttagtttgct ccaaggactt cggtagatgg acatacaggt 11700 atttaggact ttagcaatga ctgctacgca aataatttat tttcaaaaaa ctattcgaaa 11760 tcaaaataac aaaaaaagta aatatttaaa cacaataatt gagggacagt ttttctttga 11820 caaaatacta atataggaat ctaagggcga gagattgaga ttaaaattat agtacaatta 11880 ttttaccctt gagaccataa ttgtagcaat ttctgatgta tcgattcata atcagtgtct 11940 tttctggttt ttggcacatg tattgagcgc tgtctagcat gactacgtgc actcatggat 12000 gcattaagag aagctgattg taccccatca tctttcttcg aagtctcggc agaagcgacg 12060 atgccgtttt gtccgttact aattgtctcc tccctagttc cagcggtacc tgccgcagaa 12120 gtattgaagg cattttgaga gtcgaaattc tgattgttac tataggagga ccttattttc 12180 tctaagaatt cagggatcaa ctcacgcgta cgcaaaacat tccgatattg tgtacggact 12240 aagtccataa tatgctttgt atgagggttc gaaaaccgtt tagaagggtt tgtatccata 12300 tcatcttcta ctatgtcaaa tttagaagat gcacgttgaa tcaacagctt ttgctgggtt 12360 ctacttgtgg aagagccaag gtcgtaaagt tcagcctgcg acttttttac atttgtggaa 12420 ggaacttttc gatttgcaag taacgataaa gaatttcctc tagagagtgt agggggttca 12480 ctagcaatat ctaaaagtaa gttaatatat gagtaatatg aattgatgaa acatcgatta 12540 aagacttacc cgagcccgaa tgaatttgcc attttggctg atttgtagcc tgagtgactt 12600 cgcgattatt cgaatgaggt aaaggttctg ccataacttc attatgtact gggctcgatt 12660 ttgtggtact agcatcagca gctgaatcgt cttgaccggc agcgggtgga cgagcagaag 12720 cttgaacatc tgtattatta aagggaggag catttgaaat attcgaatta atgattttct 12780 ttttgttatc atgaacagca acaactctgg tgacaggaga gctggctctt gaagaatcag 12840 ccgcttcgtt cgtagtgaca gaaggcgtag gaagcgcact gtccgaatcc aaattaccag 12900 cagtagaatc attgtcaact ggagcatcgt cccaaacaca atttggtttt ctttgtgtta 12960 gtggtattaa tccatttttg gctacgtgtt taggaccatt gagttcatgc aagtcgttga 13020 gagatcgttg tttagtaaga tgggacacgg cggacgaatt gtttaccaaa ctactatttg 13080 gattttgaga atgcgctcga gttaaagcag aaggtctcat agttacactg cccaatctac 13140 ctgaacggtt gactcgcaca tgacctccac cacgcttaag cctactgttt acaataaaat 13200 tccgcttacg ctccttagta gatcttgagt aaaccccttc accatctgta cttactgtag 13260 aagaggacgt tcttctcgac agggatggac gttccatact aaacgtctaa atgagggttc 13320 tttggggaac tgtttagaaa gaaaatgaag aagaaacgaa tacaagcaaa acgcttgtaa 13380 attaaccttt gaaatgatta attgagtaaa atatgaacat gaagaggaat ccaataaaaa 13440 gctagtcaat tcccaattat gactaacaaa aacaatggat caataatgta aaagaacgat 13500 attaaaaaaa atatttaatt attaattttt ctcacttgtc aattcctact cctgaagtga 13560 ataaattagc aggttaagaa ttcgttcgcc aagataggtg aaaggaaaga gaggatggag 13620 gtgtgtcaat gtgaaacgaa caaaagatgg caaatattat aaaacggcta tagcgtgata 13680 tcgtttgtta aaatattaga tttatttcaa ttcactattt tctagctcaa taagtgcaat 13740 ttatcattac taaaggcatg ggtaatatat tacaacaaac gttggtaaaa ggaagatgag 13800 gaatttagtc atgtggtact cttt 13824 //