ID SPCC162 standard; DNA; FUN; 37960 BP. XX AC AL023860; XX SV AL023860.2 XX DT 10-JUN-1998 (Rel. 56, Created) DT 29-NOV-1999 (Rel. 61, Last updated, Version 4) XX DE S.pombe chromosome III cosmid c162. XX KW 3-hydroxy-3-methylglutaryl-coenzyme a reductase; coiled coil; hmg1; KW possible dehydrogenease; putative methyltransferase; KW putitive uridine kinase; serine/threonine protein kinase; KW short chain dehydrogenase. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-37960 RA Murphy L., Harris D., Wood V., Rajandream M.A., Barrell B.G.; RT ; RL Submitted (09-JUN-1998) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk. XX DR GOA; O74419; O74419. DR GOA; O74420; O74420. DR GOA; O74421; O74421. DR GOA; O74422; O74422. DR GOA; O74426; O74426. DR GOA; O74427; O74427. DR GOA; O74628; O74628. DR GOA; Q10283; Q10283. DR SPTREMBL; O74418; O74418. DR SPTREMBL; O74419; O74419. DR SPTREMBL; O74420; O74420. DR SPTREMBL; O74422; O74422. DR SPTREMBL; O74423; O74423. DR SPTREMBL; O74424; O74424. DR SPTREMBL; O74426; O74426. DR SPTREMBL; O74427; O74427. DR SPTREMBL; O74428; O74428. DR SPTREMBL; O74628; O74628. DR SWISS-PROT; O74421; COQ3_SCHPO. DR SWISS-PROT; Q10283; HMDH_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC c162 is overlapped by SPCC1753 at its 5' end, and CC SPCC13B11 at its 3' end. XX FH Key Location/Qualifiers FH FT source 1..37960 FT /chromosome="III" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c162" FT /map="IIIR" FT CDS join(complement(356..1103),complement(1..296)) FT /db_xref="SPTREMBL:O74428" FT /label=SPCC162.12 FT /note="SPCC162.12, len:348" FT /partial FT /gene="SPCC162.12" FT /gene="SPCC1753.06c" FT /product="hypothetical ser-rich protein" FT /protein_id="CAA19592.1" FT /translation="MERPSLSRRTSSSTVSTDGEGVYSRSTKERKRNFIVNSRLKRGGG FT HVRVNRSGRLGSVTMRPSALTRAHSQNPNSSLVNNSSAVSHLTKQRSLNDLHELNGPKH FT VAKNGLIPLTQRKPNCVWDDAPVDNDSTAGNLDSDSALPTPSVTTNEAADSSRASSPVT FT RVVAVHDNKKKIINSNISNAPPFNNTDVQASARPPAAGQDDSAADASTTKSSPVHNEVM FT AEPLPHSNNREVTQATNQPKWQIHSGSDIASEPPTLSRGNSLSLLANRKVPSTNVKKSQ FT AELYDLGSSTSRTQQKLLIQRASSKFDIVEDDMDTNPSKRFSNPHTKHIMDLVRTQYRN FT VLRTRELI" FT misc_feature 1..1630 FT /note="nominal overlap with cosmid SPCC1753, EM:AL035210 S. FT pombe chromosome 3" FT misc_feature complement(297..311) FT /note="ttaacttacttttag, splice branch and acceptor" FT misc_feature complement(350..355) FT /note="gtaagt, splice donor sequence" FT CDS 3353..4717 FT /db_xref="GOA:O74427" FT /db_xref="SPTREMBL:O74427" FT /label=SPCC162.11c FT /note="SPCC162.11c, len:454, SIMILARITY:Caenorhabditis FT elegans., Q19583, f19b6.1a protein., (515 aa), fasta FT scores: opt: 1058, E():0, (38.5% identity in 431 aa)" FT /gene="SPCC162.11c" FT /product="putative Uridine kinase" FT /protein_id="CAA19591.1" FT /translation="MPEAFERYSSNPTYEPPWRKVRFIGIAGPSGSGKTSVAQLIVKAL FT NLPHVVILSLDSFYKSLNAEQKKRAFNNDYDFDSPEAIDWDLLFVKLLELKQGRKVDIP FT IYSFNEHNRLPETNTLFGASIIILEGIFALYDEKIRSLLDVSVFLDTDSDVCLSRRLNR FT DINYRGRDIVGVLEQYNKFVKPSYENFVRRQLSYTDLIVPRGRDNKLAIDMVINFIRRT FT LSIQSETHVKNIDSLQQIVPTIPHLPLNLVQLKITPEISAIRTILINKNTHPDDLQFFL FT SRIGTMLMNLAGDSLAYEKKTITLHNGNQWEGLQMAKELCGVSVLRSGGTLETALCRQF FT PTVCLGKILVQINKVTQEPTLHYHKLPRGIATMNVVLMASHLTTHADVLMATQILVDFG FT VPEENIIIVVYVCYSESIKALAYIFPKVTIVTAFLESVAEPVVGRLDIEKVYYGC" FT misc_feature 3434..3457 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS complement(5132..6148) FT /db_xref="GOA:O74426" FT /db_xref="SPTREMBL:O74426" FT /label=SPCC162.10 FT /note="SPCC162.10, len:338, SIMILARITY:Caenorhabditis FT elegans., Q21483, m03c11.1 protein., (379 aa), fasta FT scores: opt: 511, E():2.2e-24, (32.6% identity in 316 aa)" FT /gene="SPCC162.10" FT /product="ser-thr protein kinase" FT /protein_id="CAA19590.1" FT /translation="MGNSNSKSVKNDKENFEDPNATNFESVSQFKIRNVIGKGSWSTVF FT VVKHRQTKQRFALKCINKKKHDEHKIKKLRNEVLLLQSLNHPLLCKFYSEFEDETKIYL FT VTDLMLGGDLRYHISQRKFNESVIRIWMVELVSALIYIHSKGVLHRDVKPDNILLDEKG FT HCKLADFNVAAKVHTSSSPSKSNMTVGRVGTPVYMAPETLIHAVSYKESDWWSLGITFY FT ECLFQVRPFPNHLLINWIRASEEEKASSADRLSSALHISRDKKLTTISKDARSAVMAFL FT EMDIKKRLGHSSKKLQTHPFFCSISLETVSKGNLTPIFRPKSGKVYVDPILDLEATF" FT misc_feature complement(5243..6061) FT /note="Pfam match to entry pkinase PF00069, Eukaryotic prot FT ein kinase domain" FT misc_feature complement(5672..5710) FT /note="PS00108 Serine/Threonine protein kinases active-site FT signature" FT misc_feature complement(5972..6043) FT /note="PS00107 Protein kinases ATP-binding region signature FT " FT CDS 8894..12055 FT /db_xref="GOA:Q10283" FT /db_xref="SWISS-PROT:Q10283" FT /label=hmg1 FT /note="SPCC162.09c, len:1053" FT /gene="hmg1" FT /gene="SPCC162.09c" FT /product="3-hydroxy-3-methylglutaryl-coenzyme a reductase" FT /protein_id="CAA19589.1" FT /translation="MIYKLAARYPIQVIAIVGILVSMAYFSFLEALTQEDFPVLIRALK FT RFGILDGFPNTRLPNEMILKLSSVQGEDASVWEQIPAAELGGEGFVDFDITQWYYPANA FT KVDVAQLVEPYRNDCIFHDASGACHFFFKEVGNWTVSSIALPSNLANPPIDYFLDSSST FT VIQRILPAIREHGISWSWLLQLIARTWMNTLKIASQASKTELLIVGTAYACMLISIVSL FT YLKMRRLGSKFWLFFSVLLSTLFSVQFAMTLVRASGVRISLVSLIESLPFLINVVALDK FT AAELTRQVITRCSVSDSHSPMHEDIAKACRNAAPPILRHFSFGIVVLAIFSYCNFGIKQ FT FFLFAAVMIYDLLLLFSFFVAILTLKLEMRRYNAKDDVRKVLIEEGLSESTARHVADGN FT DSSATTSAGSRYFKVRYGTKIILFIFIAFNLFELCSIPFKHYAATSAAAARLIPLVRSQ FT YPDFKSQRLLDDGVFDDVLSAISSMSNIESPSVRLLPAVFYGAELSSTSFLSTIHSFIN FT NWSHYISASFLSKWIVCALSLSIAVNVFLLNAARLNSIKEEPEKKVVEKVVEVVKYIPS FT SNSSSIDDIQKDEIAQESVVRSLEECITLYNNGQISTLNDEEVVQLTLAKKIPLYALER FT VLKDVTRAVVIRRTVVSRSSRTKTLESSNCPVYHYDYSRVLNACCENVIGYMPLPLGVA FT GPLIIDGKPFYIPMATTEGALVASTMRGCKAINAGGGAVTVLTRDQMSRGPCVAFPNLT FT RAGRAKIWLDSPEGQEVMKKAFNSTSRFARLQHIKTALAGTRLFIRFCTSTGDAMGMNM FT ISKGVEHALVVMSNDAGFDDMQVISVSGNYCTDKKPAAINWIDGRGKSVIAEAIIPGDA FT VKSVLKTTVEDLVKLNVDKNLIGSAMAGSVGGFNAHAANIVTAVYLATGQDPAQNVESS FT NCITLMDNVDGNLQLSVSMPSIEVGTIGGGTVLEPQGAMLDLLGVRGAHMTSPGDNSRQ FT LARVVAAAVMAGELSLCSALASGHLVKSHIGLNRSALNTPAMDSSAKKPATDALKSVNS FT RVPGR" FT misc_feature 11267..11365 FT /note="Pfam match to entry HMG-CoA_red1 PF00368, Hydroxymet FT hylglutaryl-coenzyme A reductase" FT misc_feature 11693..11776 FT /note="Pfam match to entry HMG-CoA_red2 PF00369, Hydroxymet FT hylglutaryl-coenzyme A reductase" FT CDS 12550..18063 FT /db_xref="SPTREMBL:O74424" FT /label=SPCC162.08c FT /note="SPCC162.08c, len:1837, SIMILARITY:Homo sapiens, FT Q99968, nuclear pore complex-associated protein tpr, (2363 FT aa), fasta scores: opt: 1057, E():0, (22.7% identity in FT 1831 aa)" FT /gene="SPCC162.08c" FT /product="putative nuclear pore complex-associated protein" FT /protein_id="CAA19588.1" FT /translation="MHDSSWTEADILGVCSFLDIPKTKIDPLLQVDAFTSILIPLISKS FT KDYESIKNDRIVTEVNYEQQLRNSEKKLLQSNERYDLLEDERKLLENELSQIKEYLREK FT SSSYDTVLHDCSSLKSVNEALKQAQDQNLKQTAQLQNLLSDKEKEVEKKITIIKDLKDA FT LASSTHQVLELQHTQQEKASLQTNYEFELQKLTQKNSILENNNTWLSRELQGVNDKLLS FT LHQEASLEKSQLSSQLSDAVLEKDALQRKVSSLSQQFTESNLRYQNIVAELSEMRKQYE FT FSQVSFEKEISSQKQISELWMEKCEDCSLRLKELQNSNGELEKLLEAAQSSFEEQLESH FT KEAEASLKSQINFLEKEVSSLESQLKLANERLRHYDEIEISDMSELKYSNLLNNSMKGF FT KGQSSVSDLYSERLYYKQKYEQTCQEVERLQRSYNHVMEEANLQHPLVKEQFKRFAHMQ FT REIVAMSEQYQKSLEDCQKAKSRYEQLETLFKDKCTENKHYEQETKDLARQVQVLLHEL FT DLCENGIVLGVDSRKKINSYVEKSLTEDETDTDQIISSRLVVFRNIRELQQQNQNLLSA FT VHELADRMEKDEKPDLDGAEIQEETLIKANETIDQLTKMLEEVSDQLRYSLKERDFFRS FT LVQENEKLLDMAPATPNSKLNTNLIEQTSYQRSLIRLEQLTNELESLKSISRNKEKKFE FT EAISSLQLEKSNIQLQLTSLTSERSLALEKLNDLEKSLVLSERSKDELDESYKSLQEQL FT ASKKIEVQNVSSQLSICNSQLEQSNHIVDNLKSENLLLTSVKDKLKADLSNLESKLSSL FT QQDNFHMKAQIESSNQEYTATVDSMNSRILELSNDLRVANSKLSECSDDVRRLTLQNSF FT DLREHQTLVLQLQSNITELKQDITLQRTVRNQLEIQTTELKERLKFMEERQENLQSKLI FT AANKDTTQNPDNVEVEAISIELERTKEKLRMAELEKSNIQQKYLASEKTLEMMNETHEQ FT FKHLVESEISTREEKITSLRSELLDLNKRVEVLKEEKESSSKELAKQLEDAVREKDSAL FT SFKKDYEKIRSDADRVITSLKEDIEKERSLMKECHSNYESEIVSHGRTTQKLRDLRTEF FT DEVNTKYLKLKANFEQQHSGLSGAEKDWNIQRKAMEDEISSLKDYILGLENQNKLLHSQ FT FDSLSQQITVLQQNSSENLNISANLEAVQDNDLRELVSYLRHEKEIMDNKYELTILDNR FT GLNQQVKSLQSTVDSLQLELNRLQSLPVSNDQTDTPIISGSQEVQLLYESNSVLRKDND FT AKLGKIQELEKEVEKLNASLNPLQTEINELKAEIGAKTASLNLMKEYNSRWKLRFQSVL FT NKYERVDPTQLEELKKNCEALEKEKQELETKLQETAKETDTFKQQVNSLNEEVENLKKE FT VEQANTKNTRLAAAWNEKCENLKKSSLTRFAHLKQELTNKNKELTSKNAENEAMQKEIE FT SLKDSNHQLQESASSDAEQITKEQFEQLKSEKERTEKELADSKNELEHLQSEAVDADGK FT TEISNLEKEIHELRSDKEGLVQQVQNLSAELAALREHSPTQGSLENADEIARLRSQLES FT TKQYYEKEKETEILAARSELVAEKEKTKEELENQLNEKSQRIKELEEQAQKNSSENTHD FT NIDDMIKQQVEEKLKENSANFDVKLKKVVAETEFRSKAKISVYEKKTRDLQNKITQLEE FT TIENLNKQLSNPEKTDESTSSVTETKPVTSKPTASKADVGQNATEASSAKREPSGKSLS FT ARLQGTGKQKGVQRPAVSRPVPMKPDSGKLSITGASKRIATSKNAAQNAKELSSTAKSG FT SLKRQRDDANKGGSSSNQKKAK" FT misc_feature 17089..17112 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS join(complement(20924..20958),complement(18556..20641)) FT /db_xref="SPTREMBL:O74423" FT /label=SPCC162.07 FT /note="SPCC162.07, len:706, SIMILARITY:Saccharomyces FT cerevisiae, Q05785, chromosome xii cosmid 8167., (613 aa), FT fasta scores: opt: 690, E():1.2e-24, (31.0% identity in 717 FT aa)" FT /gene="SPCC162.07" FT /product="hypothetical protein" FT /protein_id="CAA19587.1" FT /translation="MAFSALAYNLLAKNFSKGYTDTQIKVRNATTNDSWGPSGTAMAEI FT AELTYDQNEMLEVMDIIDRRLNDKGKNWRHVFKSLSLLEYCLHNGSENVVRWAKDNIYI FT ITTLREFVYVDDNGHDQGQNVRTKAKEITSLLEDEHALKEARGDSRERDRDRDRTRSSR FT FDDDDDDRAPYEESRLSRAPSRASRYDDDDRDHRSRRRSRSRRPGRSRSRRRSRRPSPS FT AEHNSAEENDPELQRVIEESKRQAEEDAKRRNMANDSEAELQKAIQLSKEEDEARQRHQ FT REREQQEQAFMGNQQNAYQPVDFFGNPVQPQPTGFLQQQPTGFIRPQNTGFVQPQYTGF FT VQPQHTGFVQPQATGFMQPQRTGFVQPQATGFVQPQATGFVQPQATGFMQPQRTGFVQP FT QATGFMQPQRTGFVQPQATGFMQPQRTGFVQPQATGFIQPQRTGFVQPQQNGFFNPQPT FT GYMQPQRTGMMQPQRTGFSQPFESNNPFPVMQPQRTGFGQTPNAPMMAPNHTGYVHPQP FT TGLQRQTTGYTGNNNPYSRPLQSQSTGILQQQQQQSAPRLEPTKTGSNNPFAQFSNLPS FT QSTAPATKPMKPVRTGDDRFSNIAQAISTGNPMGTDSFGNIGLTRVPTQHTGSKFTNSA FT GQTIQAQATGNTHNPFQSQQATGYYKQPMQQQQNMQQPYYNQQNYNYQNQQPMQGMQQQ FT SMQPQVGSLIDL" FT misc_feature complement(20251..20622) FT /note="Match to PF01417 ENTH, ENTH domain Score 230.12" FT misc_feature complement(20642..20654) FT /note="ctaacattcgcag, splice branch and acceptor" FT misc_feature complement(20918..20923) FT /note="gtaatt, splice donor sequence" FT LTR 21632..21979 FT /note="Tf2 type LTR" FT misc_feature 21757..22887 FT /note="True extent of overlap with cosmid c13B11 S. pombe c FT hromosome 3" FT conflict complement(22860..22882) FT /note="conflict with overlap in cosmid c13B11. Amiguity wr FT t number of As, c13B11has either 21 or 24. SPCC162 has 23" FT /citation=[1] FT CDS join(24048..24116,24174..24325,24383..24794) FT /db_xref="GOA:O74422" FT /db_xref="SPTREMBL:O74422" FT /label=SPCC162.06c FT /note="SPCC162.06c, len:210, SIMILARITY:Candida albicans, FT O93996, conserved hypothetical protein, (218 aa), fasta FT scores: opt: 564, E():1.4e-23, (44.3% identity in 219 aa)" FT /gene="SPCC162.06c" FT /product="conserved hypothetical coiled-coil protein" FT /protein_id="CAA19586.1" FT /translation="MHRLFGRKPPTQPTASLTDAIDSLDKRSDSVEVKIAKLDAQLSVF FT QQKIANTRPGPGQTALKQRAMNVLRQKKIYESQLQQLQQQSFNMEQAAMTTESLKNTMA FT TVQTMQETARQLKSQSKNVSIEKIEKLQDEIQDYMDAAGELNEVLGQNMTDINVDEEEL FT DAELEALQQESSWLGDQSTAEKPSYLMPSNELPNFVDEEVAEPSTAQ" FT misc_feature 24117..24122 FT /note="gttcgt, splice donor sequence" FT misc_feature 24155..24173 FT /note="ctaatatcttttattttag, splice branch and acceptor" FT misc_feature 24326..24331 FT /note="gtatgc, splice donor sequence" FT misc_feature 24365..24382 FT /note="ctaacgacagcaatatag, splice branch and acceptor" FT CDS complement(25128..25943) FT /db_xref="GOA:O74421" FT /db_xref="SWISS-PROT:O74421" FT /label=SPCC162.05 FT /note="SPCC162.05, len:271, SIMILARITY:Escherichia coli., FT UBIG_ECOLI, 3-demethylubiquinone-9 3-methyltransferase, FT (240 aa), fasta scores: opt: 545, E():6.5e-30, (38.8% FT identity in 242 aa)" FT /gene="SPCC162.05" FT /product="putative ubiquinone biosynthesis pathway FT methyltransferase" FT /protein_id="CAA19585.1" FT /translation="MNILNKVKNVKSYTRLVRQGFLSQQRNHSVSVNEVDHFNELAKTW FT WDWDGGSRLLHLMNSTRLDFMTEVFRERNCFSGKKILDIGCGGGILSESMARLGASVTA FT VDASPMAIEVAKKHASLDPVLNGRLEYIHGSVEGSQLPTTFDVVTCMEVLEHVEQPRDF FT LFSLMEKVKPNGRLVLSTISRTLLARLLTITLAEHVLRIVPVGTHTFEKFIRADELSNF FT LKEQNWIINDIRGVCYNPLKQQWTLDKPGSSGLGLSCNYFLSAQKPMSA" FT LTR complement(26084..26434) FT /note="tf1 type LTR" FT CDS join(complement(28467..28602),complement(27963..28235), FT complement(27558..27914),complement(27031..27521)) FT /db_xref="GOA:O74420" FT /db_xref="SPTREMBL:O74420" FT /label=SPCC162.04 FT /note="SPCC162.04, len:418, SIMILARITY:Schizosaccharomyces FT pombe, O74495, hypothetical wtf5 protein., (402 aa), fasta FT scores: opt: 1516, E():0, (84.5% identity in 420 aa)" FT /gene="SPCC162.04" FT /gene="wtf12" FT /product="hypothetical wtf12 protein" FT /protein_id="CAA19584.2" FT /translation="MKNKDYPLRSSMDELSTKNDNEIDLEKGPLPEYNSEDGSTLPPYS FT EIWKYIKTVSEDSSTGPTEIANPNVERRQEFKDSHPNIYSLLRLLISVLAVIVVFFTAW FT VCVNPLEKSIFGKVAFSVTIGITCPIVFIAIFCFFETWTQAVAQCIKVTVIFLAQCVKV FT TAISLAQCVKVTAVFLAKCVKVTAVFLAKCVKVIAVGLYNSKKDLVVTIWLAWVVICFI FT LFGCVKDGRLNLNKALICSTCSISAALFFILLLVCIPIWTLKHMLFGLFQVLGVQSCVV FT IVTKGLMYLFDKHIDATGYEIEASSLFVIGNFLFFYEMGSLYIPVIYSNHTRTSRCSQK FT DAQIYREWYSFFPRYVYSTNCMNDFLLTRLGGLGNAFGGIGNAFGGIGNAIGRIGNAFR FT GANDNNDIPLGEMDVESEV" FT misc_feature complement(27522..27532) FT /note="ctaacatacag, splice branch and acceptor" FT intron complement(27522..27557) FT /note="intron confirmed by EST" FT misc_feature complement(27552..27557) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(28236..28248) FT /note="ttaatgctttcag, splice branch and acceptor" FT misc_feature complement(28461..28466) FT /note="gtaagt, splice donor sequence" FT LTR complement(28890..29226) FT /note="tf2 type LTR" FT CDS complement(29812..30690) FT /db_xref="GOA:O74628" FT /db_xref="SPTREMBL:O74628" FT /label=SPCC162.03 FT /note="SPCC162.03, len:292, SIMILARITY:Streptomyces FT coelicolor., CAB53269, putative oxidoreductase SCJ9A.08, FT (282 aa), fasta scores: opt: 477, E():2.1e-24, (32.1% FT identity in 274 aa)" FT /gene="SPCC162.03" FT /product="short chain dehydrogenase" FT /protein_id="CAA19583.1" FT /translation="MKSTFSTVLITGSSKGLGYALVKVGLAQGYNVIACSRAPDTITIE FT HSKLLKLKLDVTDVKSVETAFKDAKRRFGNVDIVINNAGYGLVGEFESYNIEEMHRQMN FT VNFWGVAYITKEALNLMRESGKGGRILQISSVAGYYPSPCLSMYNASKFAVEGLSQTIM FT RELDPNWNIAITIVQPGGMQTEWASSNMQWAKPHPAYENDRSWRPFWENYHGCEETDPN FT KAAELLYSIAKLDRPPQKLVLGHDSLELIRKQHQDIGEELESNVALSTSVAKDDFDPAS FT VETLRQNLQSM" FT misc_feature complement(30136..30690) FT /note="Pfam match to entry adh_short PF00106, Alcohol/other FT dehydrogenases, short chain type" FT CDS 31388..34333 FT /db_xref="GOA:O74419" FT /db_xref="SPTREMBL:O74419" FT /label=SPCC162.02c FT /note="SPCC162.02c, len:981, SIMILARITY:Streptomyces FT roseosporus., O30915, daptomycin biosynthetic protein FT subunit, (1590 aa), fasta scores: opt: 269, E():1.5e-09, FT (22.8% identity in 602 aa)" FT /gene="SPCC162.02c" FT /product="putative AMP-binding dehydrogenase protein" FT /protein_id="CAA19582.1" FT /translation="MLCDSSESVSFSSISKEEDTPIARLLKNAKETPDHRFISVYNERG FT IVAKYTYTELLRRVNTIAKFCDDLGLGKTVGIHMGHELDFLCSIFALWATGRTCVIFNQ FT IWSQQVVRVLVKRLNISDLLYHEYKPKFEVDTLNATSLASLPLDIDAPCIRAGLEPEVA FT LINHSSGSTGVPKSMPFLMKKYALGYDYGTPEFMNHLSTPMVMATSFALTTLSWINALY FT CNGNLLYPSSSISATCTSEAERLAWNVYYALRAGCERLIILPNLLVLTLQIMPDKEECF FT PACKLVAAGGEMVPANMYHTCKRVLPNATIYPQYGTTESGLVSFLAYNGKDTLHNKELV FT YFPGKTVKKLMLVTEDNEAVPEKIGCEGFVCVVTDVQSEPYVGDDAETIQSRNSTFINY FT DGQPAVRFADLAVWNSYKGKLGITIKGRLGRRVKRNGVFFDLKYFDQVVVGLKEVKDAF FT SFFIFNRFVLVYVPAYNGVDPVTLKQKLNKELRDHHLFSSCFPLADIPRNAAGKVDLKS FT IETYASKCLSVEDQRLPVLLNPVAIEISKIASKILQNPSLEGKDAPLYSCGLDSIHSVR FT FFHAIQSHFHLEGPIRYNMNSNCTPNSIASIIQKKSYNVSSITYELLNEDACALSRTIP FT KLSILPTNGQYFLLTGATGYFGRRFLEYLVKLNISVVCLVRESSDEAAKERLISLVPSL FT RISSENIIVWAAHVEEIRFGLDDAKWEFLVENVSRIYHMAAEVHWMKSYQELRPANVLG FT TKTVLELSVMGPKALYFISGGGQQEVELDDDTQSAKASGYALSKYVAELLCRKISDLGH FT PLIYVIRPGFIIANDGEILSRDFFWRFVATALRMGIWPQSDESQSLVFHISTTDALCMT FT LTQILEKEADAYAPLLAYDKFDGDEFACICESMKNVKLDFVTLEDWLKALEKDVDEKGE FT DHPLFALQHATKFALKSSMTPSNGLRNIYPLSETFLTKEAIANGLENLYIE" FT misc_feature 31538..32764 FT /note="Pfam match to entry PF00501 AMP-binding, AMP-binding FT enzyme, score -197.80, E-value 0.00022" FT misc_feature 31880..31915 FT /note="PS00455 Putative AMP-binding domain signature" FT CDS 34777..35511 FT /db_xref="SPTREMBL:O74418" FT /label=SPCC162.01c FT /note="SPCC162.01c, len:244, SIMILARITY:Homo sapiens, FT Q15410, nucleic acid binding protein, (163 aa), fasta FT scores: opt: 265, E():4.5e-08, (36.0% identity in 172 aa)" FT /gene="SPCC162.01c" FT /product="putative nucleic acid binding protein" FT /protein_id="CAA19581.1" FT /translation="MSSSRSGEHRRNYAQGRNYESSRSRGDQRDRDYREYRRNYRDERS FT SRRYEDSQRRDYSPARRRDRYERHRESVREESPRRPVEHERNWQPELKHGRERFRERDY FT EGRRDRKERRDGVSPFSPEGEGLERKREHEKLQAPSPKEEEERPVDQGDKMDGVKEDKD FT GSLEVGKSHDAMTRTKSAEEEIVEQEDEATAEMKRIMGFSGFDTTTGKKHGDVGQVYKQ FT KKTKYRQYMNRPGGFNRPLDNE" FT misc_feature 35266..35289 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 35756..37960 FT /note="nominal overlap with cosmid SPCC13B11, EM:AL032681 FT S. pombe chromosome 3" XX SQ Sequence 37960 BP; 11929 A; 6773 C; 7321 G; 11937 T; 0 other; gatcaactca cgcgtacgca aaacattccg atattgtgta cggactaagt ccataatatg 60 ctttgtatga gggttcgaaa accgtttaga agggtttgta tccatatcat cttctactat 120 gtcaaattta gaagatgcac gttgaatcaa cagcttttgc tgggttctac ttgtggaaga 180 gccaaggtcg taaagttcag cctgcgactt ttttacattt gtggaaggaa cttttcgatt 240 tgcaagtaac gataaagaat ttcctctaga gagtgtaggg ggttcactag caatatctaa 300 aagtaagtta atatatgagt aatatgaatt gatgaaacat cgattaaaga cttacccgag 360 cccgaatgaa tttgccattt tggctgattt gtagcctgag tgacttcgcg attattcgaa 420 tgaggtaaag gttctgccat aacttcatta tgtactgggc tcgattttgt ggtactagca 480 tcagcagctg aatcgtcttg accggcagcg ggtggacgag cagaagcttg aacatctgta 540 ttattaaagg gaggagcatt tgaaatattc gaattaatga ttttcttttt gttatcatga 600 acagcaacaa ctctggtgac aggagagctg gctcttgaag aatcagccgc ttcgttcgta 660 gtgacagaag gcgtaggaag cgcactgtcc gaatccaaat taccagcagt agaatcattg 720 tcaactggag catcgtccca aacacaattt ggttttcttt gtgttagtgg tattaatcca 780 tttttggcta cgtgtttagg accattgagt tcatgcaagt cgttgagaga tcgttgttta 840 gtaagatggg acacggcgga cgaattgttt accaaactac tatttggatt ttgagaatgc 900 gctcgagtta aagcagaagg tctcatagtt acactgccca atctacctga acggttgact 960 cgcacatgac ctccaccacg cttaagccta ctgtttacaa taaaattccg cttacgctcc 1020 ttagtagatc ttgagtaaac cccttcacca tctgtactta ctgtagaaga ggacgttctt 1080 ctcgacaggg atggacgttc catactaaac gtctaaatga gggttctttg gggaactgtt 1140 tagaaagaaa atgaagaaga aacgaataca agcaaaacgc ttgtaaatta acctttgaaa 1200 tgattaattg agtaaaatat gaacatgaag aggaatccaa taaaaagcta gtcaattccc 1260 aattatgact aacaaaaaca atggatcaat aatgtaaaag aacgatatta aaaaaaatat 1320 ttaattatta atttttctca cttgtcaatt cctactcctg aagtgaataa attagcaggt 1380 taagaattcg ttcgccaaga taggtgaaag gaaagagagg atggaggtgt gtcaatgtga 1440 aacgaacaaa agatggcaaa tattataaaa cggctatagc gtgatatcgt ttgttaaaat 1500 attagattta tttcaattca ctattttcta gctcaataag tgcaatttat cattactaaa 1560 ggcatgggta atatattaca acaaacgttg gtaaaaggaa gatgaggaat ttagtcatgt 1620 ggtactcttt tgtttatttt aaaaagcgtt ttatttggtt taaattgcag ttacagtttc 1680 aattctacag caagtttatg ataaaacttt tcgagtaaat gtgatgtgaa attcaaggat 1740 ttttttctaa tcaaatgagg aggggaagat atctacttta atttaataaa tcaattgatt 1800 ccattgctat cgatacatgg ataattaatt tgtgggattg agaagaaatt atgcgaacaa 1860 attatctagg cttaatattc atgagtttcg agttttaaat atgaagtcaa aatttgcgca 1920 attcgaggtc atcaatgtca tttttttgtg acgattagcc gtcaaatatg tttaacattg 1980 caccggcttc aaatctttgc gtttgatgca ttcactattc tatattttca cttctctcga 2040 tatagggaag agaaatttaa ggattttgcg tgtgctaagt aagcatgtaa atgggtttct 2100 attcgaaaat gtacgctttt ttcaaatttt tctacttttt cacaccatta atagcggatt 2160 actctacttg atgggtcaaa ctgaatatcc tttatactat tttctaattt gaaattaatt 2220 gcctattacg aacaaaagcg acgagttctc aatatcataa aacctgccat aaacttatgt 2280 ccatttactt ggttcttctg cacaaaagaa actttcatat tcctttttgt cagttctctt 2340 aggtttaaaa aaaatggcaa agctacaatc taaatcttcg agcggcaaaa tcatttattg 2400 aactttgaga cgatctcaac ctagctgttc tttttatttc atcatttttg gaaggtaaaa 2460 aataatttga atctgttttt ctaagaaatg cgtattaagt attagtcgtg ttgatttagt 2520 tatttatata aacaaagcaa gatttctctt gcgtttttga atttgagcca atatgttaaa 2580 tttccttatt gtcgcctatt tttattaaat acatttttaa agttaaatta aatatcaaat 2640 tttggtacaa gcttccaaca tgtcacgaat gttacaattt tcacatagtc aaaattgatt 2700 aatttcgaat attaattgcc ggatttcttt taaatctaca tataattcat taatttagta 2760 ataggtattg caaaaaaact tctcacttcc gttctacaaa caaactgctc tttctttatt 2820 cccgatgatt accgcggctc aggcgctgac tgaaaaagtc acagtgataa tgttaccaaa 2880 ggatgaaaaa acaatgatat tggatttacc cttctccaat ttattgtttc aactagttta 2940 ctagttattt aaaaagacat ttcgaaaatc tttctattta tgttaaaatt tcctaacatt 3000 tttccttcct ttgggttcgt atacatatat atatttttct aatggtattg ctaactcgag 3060 atttgtgatt tatagaaaaa actaagcaag tttgagaaga gtaagataag gaaaccatta 3120 tcattctact tgaattaatt ctgtttgaat aaatatcttt ggctctacaa attgtggaat 3180 attttcgttt cacgccaaga cagaatttac cttttaaaaa acgttaggtt caccaattag 3240 tctttttttg ctctacagtt tttttttttt taaactttct ttagtaatat ttccttggag 3300 gctagcatac cttttttttg ggcttcttat ttattttatt tctttcgtta ttatgcctga 3360 agcttttgag cgttattcaa gcaacccaac ttatgaaccc ccatggcgta aagtgcgatt 3420 tattggaatt gcaggaccat cgggtagtgg gaaaacctcg gtggcccaat tgattgtaaa 3480 ggcgttaaat cttccacatg ttgttatttt atcccttgac tcgttttaca aatctttgaa 3540 tgcagagcag aagaagagag catttaacaa cgactatgac tttgattccc ccgaagccat 3600 tgattgggac ttgctcttcg taaaactgct agaacttaaa caaggccgta aagttgacat 3660 tcctatatat agcttcaatg agcataatcg gcttcctgag accaacacgt tattcggagc 3720 aagtatcatt attctcgaag ggatttttgc tttatacgat gaaaagattc gctctctcct 3780 tgacgtctcg gtctttctag atacagattc ggacgtgtgt ctctctcgtc gactgaatcg 3840 cgatatcaac tatcgaggaa gggacatagt tggcgttttg gaacaatata ataaatttgt 3900 caagccaagt tatgagaact tcgttaggcg tcaactatct tacactgatc ttatcgttcc 3960 tcgtggccgg gacaataaat tggcaattga tatggtgatt aattttattc gtagaacact 4020 ttctatacaa agtgaaactc atgttaagaa cattgatagt ttacagcaaa ttgtaccaac 4080 cattccccat ttacccttaa atttagttca gcttaaaatt acgcctgaaa tatctgccat 4140 caggactatt cttataaaca aaaatacaca ccctgatgat ttacaatttt ttttgagcag 4200 aattggcacc atgttgatga atttggcagg tgattcgctt gcatatgaaa agaaaacgat 4260 tactttgcat aacggaaacc agtgggaagg tctacaaatg gcaaaagagc tttgtggtgt 4320 ttcagttttg cgatccggcg gaactcttga aacagcttta tgtcgtcaat ttccaacagt 4380 gtgtttgggt aagattttgg tgcaaatcaa taaagttact caagaaccaa ctttacatta 4440 ccataaattg ccccgtggca ttgctaccat gaatgttgtt ttgatggctt cacatttaac 4500 tacacatgca gatgtcttaa tggccacgca aattttagtg gatttcgggg tcccagagga 4560 aaacattata attgtggtct atgtttgtta ctctgaaagt attaaagcgc tggcttatat 4620 tttcccaaag gttaccattg ttacagcatt tctagaaagt gttgctgaac ccgtagtcgg 4680 tagattggat atcgaaaaag tgtattatgg atgctgatat aacatttata tgcgtggata 4740 taaaaaacaa aagtttaatg tctgttagga gtttagtgta cattttatta aagaattccc 4800 tttgtttgga ttattacttg cagaaaacta cggataacag gtgtttggtg atataaatgt 4860 catattaatt aattcgtgta atttcgtatc gctcgattag aatagttcag aaattcaaag 4920 ttataaataa tgaagtttga aatagtttaa gtggaaacgc agtcaaaatt tttccaggga 4980 aaataagaga cgagactatc aggcaagcaa aaaaaaatag taaaaaaata gcaatactat 5040 gtaacacatg aaccgaaaga caaatcgtag ctgagagaat ctttgaataa tcatatatat 5100 taattagttt tgtaaacatt gaatcattag tttaaaaagt agcctccaaa tctaaaattg 5160 ggtcaacata tacttttcca gatttcggac ggaaaatagg agtcaggttg cccttggaaa 5220 cggtctccaa agagatagag caaaaaaatg gatgtgtttg aagtttcttg ctggagtgac 5280 ccaacctctt cttaatgtcc atttctagaa aagccataac agctgaacga gcatctttcg 5340 agatagtagt tagcttttta tcccgagaaa tatgaagagc agaagataaa cgatctgctg 5400 atgaagcctt ttcttcctct gaagctcgaa tccaattgat caaaagatga ttgggaaaag 5460 gtcgcacttg aaaaaggcat tcgtaaaatg ttatacctaa ggaccaccag tctgattctt 5520 tataagaaac agcgtgaatt aatgtctcag gagccatata tacaggggtc ccaacgcgac 5580 caacagtcat gtttgattta gaaggagaag atgaggtatg cactttagct gcaacattaa 5640 agtcagccaa cttgcaatgt cccttctcat ccaacaaaat attatctggc tttacatcgc 5700 gatgaagcac cccctttgaa tgtatataaa tcaaggcaga tactagttct accatccaaa 5760 tacgaatgac cgattcattg aattttcttt gggaaatatg gtatcggaga tctccaccaa 5820 gcattaaatc agttactaag taaattttcg tttcatcctc aaactcagag taaaacttgc 5880 atagtagagg atggttcaat gattgtaata atagaacctc atttcttagc ttcttgatct 5940 tatgctcgtc gtgtttcttt ttattgatgc atttaagagc aaacctttgc ttagtttgac 6000 gatgtttcac gacgaacact gtactccagc ttcctttccc aataacattt cgaattttga 6060 actgagaaac actttcaaaa ttggtggcat ttggatcctc aaaattttct ttgtcgtttt 6120 taacactttt tgagttacta tttcccatgt ataaaaaact gcggaaagaa agcacaaagg 6180 tgcagcaatg tctatttgac tttggtggat agggacgcta gcgaacaatt aatttacatt 6240 tagcatttca aaatgaaaac tcacttttga ctcaagcgct gcgacgcctt aatttgagta 6300 aacggtcctg tagttcgata gcttgactag tgtaaaaaaa aaataaagag agagaattcg 6360 gtttttttct tgaaaacgag tgttaaaaaa ttatttatta aatttggttt tggataaatc 6420 agagaattat ggagtctgta gattcaccat acctgtagtc aggaggtaca gagaacaaag 6480 aaacttagca atttatgggt aaacaaagaa tcagggagat gatgcttctt caatagagtc 6540 gtttaaatgc aactttaaaa cttatccttt tgattggata aaattaaaat tagcgaagct 6600 tatgttattt ctcaaaacga ccattggttg tagataactc gttaatagta atcttaaatt 6660 aacccaagga agataaccac atttagttgg tgagagtgaa aaagcacatt acacgttttc 6720 tacactgaat ttcctttaaa aacagaaatt ttcacaaatt tccttgttgt tttaactgtt 6780 agtataattt ttcttccatt ttgggacaac ctacgttaag agaaacttcc ttccccacag 6840 tgtacaagag gtggctgaaa actgcaatgg aagtacaatg cagtacggag gtttctacat 6900 aataagttcc cctaataaaa cacctacaaa agaagcatag tgaccctgct tcttttttct 6960 ccttcaccta taatactgtt gcttcgttga gatcagtgct tctctctaca aaagaatttc 7020 caaacttatc gtaatgcgtt gccagagtta aggcctatgt ccaaagcttt attttaaaat 7080 gctggagaga acagaaagtg gaacttaata tgcatagtaa atataagaat aacagaagca 7140 ggattttgta agtctaaaga tatttttagg tttggataca ctcattcctc ataaaagaaa 7200 aaggaaggaa aagggcgttg ttcatttttt taaaaggaat aaagaaccgt caaatgattt 7260 taccggtttg tcgcattagc ctaatttgga tataattcga aattgtataa aaggtatcca 7320 attttttcct gcgtcttgta agtcaatctc cgataaataa gagattaatg tgaaaataat 7380 gccttcatga gaaacaactt atttcaacca catctcattc tcagcaatca cagagttcca 7440 ttatagacgt tgataaaaaa aataatataa agaataagtg cagcaattac ttcgtccggc 7500 ttcaatttgt cctttttaca aagtcaaagt tttcgaattg tcttgaagca aacaacccta 7560 cacagatctg tctgtcatag gtaacgctta atatctctta ggaaatgaag tataacgact 7620 gtgatttcca agcgcttcat cttacctttt aacgagattg gatcaagagc cttggaataa 7680 tttcgtttct cttaagttta attcccatcg tccattcgct gctctttctg atatatgatt 7740 aacgatttct ttaaacatct cggtgaatac gagatttgaa ctccttcact atttccttag 7800 aagcttaaat cctctttcta agaagtaatt tttggctggc aaccaagcaa gtcatgctct 7860 aaagttttat gatcgttcaa aaaaataatc caactaacgt ctttggcatt tcgtctaatc 7920 aaaccttgga agtcgctttt catcgacaat ttcttagctt aaacttgaca aatagattac 7980 attttttcta caatattcaa gcatttcttt aacatttttt ggaactagta ctttcaagta 8040 gggtccttta cttttttttt taaacaacgg acgagcgcag tttttgcacc ccaacaagta 8100 gcacttcaat cttaacttac ccacaacaac accacgccat aatttgaaat ctcaactctc 8160 gtctttgcaa gacgctggtt tacctcaata aatattagaa gtgaaaaacg ttgatatttt 8220 gtcagcgaag ttcctttctc gctctattta cttttctatc ttggtaaata gcccgttttt 8280 tcctggaaac cagtctcccc ttggtacgta aaatcttgct tctttttttt tataaaaaaa 8340 aagaaagaga aaaattatag ggaagataga ctttgacgaa caaagaagaa gcggttgtca 8400 gttttggttt cttatcaaac tcaccatcct ttatacttgc tagtggtcaa ttttttgggt 8460 aacctttttt gaactactcg agtgggttcc tttgtttttt ttttcgttat cctcattttt 8520 cgttttgaag gagttacttt caactctttc cattctttgc tctttgtgct tacgttattt 8580 tgaacaaagt tgattgaaat ctaagaagtc ctttttcaat actttatttt attatttaat 8640 ttctttctga acgttgatat atatacctat tatttaatat ctatataatc atctacgctt 8700 atcacagaca acgaataatt tataatcttc atttaattgc tacagttgtc tgctcttcgg 8760 tttcaataag ttaaagtgtt tgcgttacgt gtttgtacgt attcatcaac cgtgtgcgct 8820 tgtccttgat tttttaattg tcgcaaaaga aaaggagaac tgttagcttt ttgtcataag 8880 tttttcagtt aacatgattt ataaacttgc tgctcggtat ccaattcaag tgattgccat 8940 tgtgggcatc cttgtctcta tggcatattt ttccttcttg gaagccttaa ctcaagaaga 9000 tttcccagta ttaattcgtg ctttaaaacg atttggtatt ttggatggat ttccgaacac 9060 tcgtctacct aacgagatga ttttaaagct aagtagtgtc caaggtgagg atgcctcggt 9120 ttgggaacaa attcctgccg cagagttggg tggagaagga tttgttgatt ttgatatcac 9180 ccaatggtat taccctgcga atgcaaaggt cgatgttgct caattggtag agccatatcg 9240 taatgactgc attttccatg acgcttccgg tgcttgccat ttctttttta aagaggtcgg 9300 caattggact gtatctagta ttgcattacc atcgaatctc gccaatccgc ccatcgatta 9360 cttccttgac agttctagta ctgtcattca aagaattctt cctgcaattc gtgaacacgg 9420 catttcatgg tcgtggttac ttcagttgat cgctcgcact tggatgaata ctttaaagat 9480 cgctagccaa gcttctaaga ccgaactgtt aattgttggt actgcttatg cttgcatgtt 9540 gatatccatt gtgtctcttt accttaagat gcgtcgtcta ggatccaaat tttggctatt 9600 ttttagtgtc ctgctttcca ctttgttctc tgttcaattc gcaatgactt tggtacgtgc 9660 atctggtgta cggattagcc ttgtctcgtt gattgaaagt ttgccttttc tgataaatgt 9720 ggttgccctt gataaagctg cagaattaac gcggcaagtt atcactcgat gctctgtctc 9780 tgactcccat tctcctatgc atgaagatat tgcaaaggct tgccgcaacg ctgcaccgcc 9840 tatcctccgt catttttctt ttggaatagt cgttttggca attttttcgt attgtaattt 9900 tggtatcaaa caattctttt tgtttgctgc tgtcatgatt tatgatttac tcttactgtt 9960 ctctttcttt gtcgccatac tcaccctgaa acttgagatg cgccgctata atgctaagga 10020 tgatgttcga aaggttctta tagaagaggg tctctctgag tctacggctc gtcatgttgc 10080 agacggcaac gattcttcgg ctactacttc tgcagggtca cggtatttta aagttagata 10140 tggaaccaaa atcattcttt tcatattcat tgccttcaat ttgtttgaac tttgttctat 10200 tccgttcaaa cattatgctg ccacttctgc tgctgctgct cgattaattc ctcttgttcg 10260 ctctcaatat cccgatttta agtcacaaag gcttttggat gatggagtgt ttgacgacgt 10320 tctttctgct atttcttcaa tgtccaacat tgaatcacca agcgtccgtt tactaccagc 10380 tgttttttac ggtgccgaat tatccagcac ttcttttcta tctactatcc attcgtttat 10440 taacaactgg tctcactaca tcagtgcttc gtttttgtca aaatggatcg tctgtgcttt 10500 atctttgagt attgccgtca acgtttttct tttgaacgct gctcgattga actccatcaa 10560 agaggaacct gagaaaaagg tggttgaaaa agttgttgaa gtcgttaagt atattccttc 10620 gtcgaatagt tcatccattg atgacattca gaaagacgaa atcgctcaag aatccgttgt 10680 acgttcgctt gaggaatgta tcactcttta caacaatggt caaatttcaa ctttaaatga 10740 tgaagaagtt gtgcagttaa ccttagctaa aaaaatccct ctttatgctt tagaacgagt 10800 acttaaagac gttaccagag ctgttgtaat tcgccgaacg gtcgtctccc gttcatctag 10860 gacgaagaca cttgaaagct ctaattgccc cgtctatcat tacgattact ctagggtttt 10920 gaatgcatgt tgtgaaaacg ttataggtta catgcccttg ccccttggtg tagctggtcc 10980 tctcattatt gacggtaagc ctttttatat ccctatggct actactgagg gtgcattggt 11040 tgcttctact atgcgtggat gcaaagctat taacgctggt ggtggtgctg ttactgtatt 11100 gactcgtgat caaatgtccc gtggaccatg tgtggctttc ccgaatttga cgcgcgctgg 11160 tcgtgctaaa atttggttgg atagccctga aggccaagag gttatgaaga aggcttttaa 11220 ctctactagc cgttttgcta gacttcaaca tattaagact gctctagctg gtactcgtct 11280 tttcatccgt ttctgtacgt ctaccggtga tgctatgggt atgaatatga tttccaaagg 11340 tgttgagcat gcacttgtag taatgagcaa tgacgctggt tttgatgaca tgcaagtgat 11400 cagtgtatca gggaattatt gtacagataa gaagcctgct gctattaatt ggattgatgg 11460 tcgtggtaaa agtgttattg ctgaagctat tattcctggt gatgctgtca aatcggtatt 11520 gaaaactact gttgaagatt tggttaaatt aaatgttgac aaaaacctca ttggtagtgc 11580 tatggctggc agcgttggag gatttaatgc tcatgctgct aacattgtca cggcagtata 11640 tttagcaact ggtcaagacc ctgcccaaaa tgttgaaagc agtaattgta taactttgat 11700 ggataatgtt gatggtaacc ttcagcttag cgtgtcaatg ccatccattg aagttggaac 11760 aattggtggt ggaacggttt tggaaccgca aggtgctatg cttgacttgc tcggtgtgcg 11820 aggtgcccat atgacctctc ccggtgataa ttctcgtcaa ctagcacgtg tcgttgcagc 11880 cgccgtaatg gctggtgaac tgtctttgtg ttccgcactt gctagtggcc atttagttaa 11940 atcccatatc ggactcaatc gaagtgcgct gaatactcct gctatggact cttctgccaa 12000 gaaaccagcg actgatgctc taaaatccgt taactctcga gtaccgggac gttgagggag 12060 caagcttgtt ttataatatt gtcacataca cgatgatgac aaattttttt aattttgatc 12120 tcccctaaaa agttacatct ttgaactgtt atgcctcagg aaaattagct ttaaattctt 12180 ttccattttt tatatattca tcttttaaaa gaatatggta tatccataca agtatgtagt 12240 ttacctagtg aacgctgatt tatagcttag gtaagaagac gtaaggcaat gtatattgct 12300 tatgtctagt gacacaaaca aatggattat attatacgga cttatattag ttatctcaat 12360 aaagaattta aatagatttt taattgtaat ggttttatga cttgaaattg aatttattag 12420 ggtatcaact acctcgtcgc tacacaccca tcgacttaca ttgcaccacc ataataggta 12480 agaacgtgtt tcaaacaaag gtagcgtctc taaactgaaa aaatagttag aagctatttg 12540 tttgaggcaa tgcacgattc ttcctggaca gaagctgata tactcggggt atgcagtttt 12600 ctagacatac caaagacaaa aattgatcct ttacttcagg tggacgcgtt tacatccata 12660 ttaatacctt taattagtaa aagcaaagat tatgaaagta taaaaaatga tcgtatagtt 12720 acagaagtca attacgagca acaattgcga aattcggaga agaaactact tcaatcaaac 12780 gaacgttacg atttattaga ggatgagcgc aagcttttag agaatgaact ctctcaaatc 12840 aaagaatatc ttagggagaa atcctcttca tatgacactg ttttgcacga ttgcagttct 12900 ctcaaaagtg taaatgaggc attaaaacaa gctcaggatc aaaatttgaa gcaaactgct 12960 caacttcaaa atcttttatc agataaagaa aaggaagttg aaaagaaaat cactatcatt 13020 aaagatctaa aggatgccct tgccagttct acccatcaag ttttggagct tcaacataca 13080 caacaagaaa aagcatcttt gcagactaac tatgagtttg agttgcaaaa attaacgcag 13140 aaaaattcga ttttggaaaa taataacacc tggttaagcc gagagcttca gggtgtgaac 13200 gacaaattgt tatctcttca tcaggaggcc tctttggaaa agtctcaact aagttctcaa 13260 ttatctgacg ctgttttgga aaaagatgcg ctacaacgga aagtgagttc tttgtctcaa 13320 cagtttacag aaagtaattt acgatatcag aatattgtag ctgaactctc cgaaatgcga 13380 aagcaatatg agttttcgca agtttctttt gaaaaagaga tttcttcaca aaagcaaatt 13440 agtgagttgt ggatggagaa atgtgaggat tgctctttac ggctcaaaga gttgcagaac 13500 tcaaacggcg agttggaaaa gctattggaa gctgcacaat catcttttga agaacagctt 13560 gaatctcata aggaagcaga agcttccttg aaatctcaaa tcaattttct agagaaagag 13620 gtatcaagtt tagagtctca gctaaagttg gctaatgagc gtcttcggca ttatgatgaa 13680 atagaaatct cagatatgag tgaattgaaa tactcaaatt tactaaataa tagtatgaaa 13740 ggctttaaag gtcagtcctc cgtctctgac ttgtattccg agcgtttata ctataaacag 13800 aagtatgagc aaacatgtca agaggttgaa aggttacaac gtagctataa ccatgttatg 13860 gaagaagcga atcttcagca tcctttggtt aaagaacagt ttaagcgatt tgctcatatg 13920 caacgggaaa ttgttgcaat gagtgagcaa tatcagaagt cattggaaga ctgtcagaaa 13980 gccaagtccc gttacgagca attagagaca ctatttaaag ataaatgcac agagaataag 14040 cattatgagc aagagaccaa agatttagcg cgacaggtgc aagttttact tcatgaactc 14100 gatttgtgtg agaacggcat agtgctaggc gtggatagta gaaagaagat taactcctat 14160 gttgaaaaat cgctcactga agatgaaact gatacggatc aaataatttc aagcaggcta 14220 gttgtatttc gtaatattag agaattgcaa caacaaaatc aaaatctact gtctgcagtt 14280 catgaattag ctgatcgtat ggagaaagac gaaaaacctg atcttgatgg agccgagatt 14340 caagaagaaa cactgataaa agctaacgaa actattgatc aacttactaa aatgttggag 14400 gaggtgagcg atcagttacg ctactcttta aaggaacgag acttttttag atcactagtt 14460 caagagaatg aaaaactttt agatatggcg cctgcaactc ctaattccaa attgaatact 14520 aatttaattg agcagacttc ttaccagcgt tcgcttattc gacttgaaca gctaactaat 14580 gaactggagt cccttaagtc aatttctcgt aacaaagaaa aaaagtttga ggaagctatc 14640 tcatctctcc agctcgaaaa atctaatatt caattgcaac ttacctcttt aacatctgaa 14700 cgaagcttag cccttgaaaa gctaaatgat ctggaaaaat cacttgtttt atctgaaaga 14760 agtaaagatg aacttgatga aagctataag tctttacaag agcaacttgc ttctaagaaa 14820 attgaagttc aaaatgtttc ttctcaatta tcaatctgta atagccagct tgaacaatcc 14880 aatcatattg ttgataattt aaaaagcgaa aacctgcttt taacttccgt caaggataag 14940 ttgaaagccg atttatctaa tttggagtcg aaactttcgt ccctgcagca ggataatttc 15000 catatgaaag ctcaaattga atcttcaaat caagagtata cggcaacagt ggactcaatg 15060 aatagtcgaa tacttgaact ttctaatgat cttcgagttg ctaattcaaa gctatctgag 15120 tgttccgatg atgttcgtag acttactcta caaaattcat ttgatttgag ggagcatcaa 15180 acattggtgc ttcaacttca gtctaacatc actgagttaa aacaagacat aacattgcaa 15240 cgcaccgtgc gaaatcagtt agaaatacaa accactgagt tgaaagagcg cttaaagttt 15300 atggaagaac ggcaggagaa cttgcaatct aaattaatcg cggctaataa agacacgaca 15360 caaaatcctg ataatgttga agtcgaggct atatctattg aactggaaag gacgaaggaa 15420 aaacttcgca tggccgagct tgaaaagagt aatattcaac aaaaatacct cgcttcagaa 15480 aaaaccttgg aaatgatgaa tgaaacccat gagcagttta agcatctagt agaatctgaa 15540 attagcacaa gggaagagaa aattacgtcc cttcgctctg agttgttgga tcttaataag 15600 agagttgaag tactaaaaga agagaaagag tcttcgtcca aggaacttgc caaacaactt 15660 gaggatgctg ttcgtgaaaa ggatagtgca ctttctttca aaaaagatta tgaaaaaatt 15720 cgttcagatg cggatcgtgt tattacctct ttgaaagaag atattgaaaa agaaagatct 15780 ctaatgaagg agtgtcattc taattacgaa tcagagatcg ttagtcatgg gcgtaccact 15840 caaaaattgc gggatttacg tactgaattt gacgaggtga atacgaaata tttaaagctc 15900 aaagcaaatt ttgaacagca gcactcagga ctttcaggtg ctgaaaagga ttggaatatt 15960 cagcggaaag ccatggaaga tgaaattagc tccttgaaag attacatttt gggacttgaa 16020 aatcaaaata aactactaca ttcgcaattt gattctctta gtcaacaaat aactgttctt 16080 caacagaatt cttctgaaaa tttaaatata tctgccaatt tagaagccgt tcaagataac 16140 gatttacgtg aacttgttag ctacttgagg cacgaaaagg aaataatgga taataaatat 16200 gagttaacaa ttctggataa tagaggtttg aatcaacaag tcaagtcttt gcaatccacc 16260 gttgattcat tgcaactcga gctcaaccgt ctgcagtctc tgcctgtgtc aaatgaccaa 16320 acagataccc ccattatcag cggaagtcaa gaagttcagt tactttatga aagtaatagt 16380 gtccttagaa aggacaatga tgctaaactt ggaaaaatac aagagctgga gaaagaggtt 16440 gaaaaactga atgcttcatt gaatccctta caaactgaaa taaatgaact taaggcagaa 16500 ataggcgcaa agacagcaag tctgaactta atgaaggaat acaattctcg atggaaatta 16560 agatttcagt ccgttttgaa caagtatgag cgtgttgatc ccacacagtt agaggagtta 16620 aagaaaaatt gtgaagcatt agaaaaagaa aaacaagagt tggaaacgaa acttcaggag 16680 acagcaaaag aaaccgatac atttaagcaa caggttaatt ctctaaacga agaggtggaa 16740 aatttgaaga aggaagttga gcaggcaaac accaaaaata ctagattggc agctgcttgg 16800 aatgaaaaat gtgaaaattt gaaaaaatcc agcttaacaa gatttgccca tctaaagcag 16860 gaattgacca acaaaaacaa ggagttaacc tctaagaatg ctgaaaatga agcaatgcaa 16920 aaagaaatag agtctctaaa ggattccaat catcaattac aagaatcggc ttccagtgat 16980 gctgaacaga tcacgaagga acaatttgaa caactcaagt cggagaagga aagaactgaa 17040 aaagagctag cagattctaa gaacgagcta gaacacttgc aatctgaggc tgtcgatgct 17100 gacggtaaaa ctgaaatttc aaatcttgaa aaagaaattc atgaattacg gtctgacaaa 17160 gaaggacttg tgcaacaagt acaaaacttg agtgcggaat tggcagcttt acgagagcat 17220 tcaccgaccc aaggaagttt agagaatgct gatgagattg caaggctacg ttcacaactt 17280 gaatctacga aacaatatta tgaaaaagaa aaggaaaccg aaattttggc tgctcgctct 17340 gaactcgtcg cagagaaaga aaagacaaag gaagagttag aaaatcaact caacgaaaag 17400 tcacagagaa taaaggaact tgaggaacaa gctcaaaaaa attcttcgga aaatactcat 17460 gacaatattg atgacatgat taagcagcag gttgaagaaa agcttaaaga aaattctgcc 17520 aactttgatg ttaagttgaa gaaggtggta gctgagacag aatttcggag caaagctaaa 17580 atatctgtgt atgagaagaa aactagggat cttcagaaca aaattacaca acttgaagaa 17640 actattgaga atttgaataa acagctatcc aatcctgaaa agactgatga atctacgtct 17700 tctgtaacag aaacaaagcc tgttacttcc aaaccaacag ctagcaaagc tgatgttggt 17760 cagaatgcta cagaagcttc gtcagccaag agagaacctt ccggtaaatc tctgagtgca 17820 agacttcaag gaacaggcaa acaaaaaggt gttcaacgac ccgctgtttc gcgtcctgtt 17880 cctatgaaac cagacagtgg aaaactctca ataactggag cttccaaacg aattgctact 17940 tcaaagaatg ctgcccaaaa cgctaaagaa ctgtcaagca ctgctaaatc cggctccctt 18000 aaaagacaac gtgacgatgc gaacaaagga ggatccagtt cgaaccaaaa gaaagcaaaa 18060 tagatgtttt catatggttc ataaatcact cttaggacta ttcatattta gttaacatga 18120 tttataataa tgacatgagt aaattttgta ttataaaatt tttgtcttat ttgtatttct 18180 gattcttaca cagactggtt tttgctattt cttgattttg caaagtaagt actttttcga 18240 cttacttatt ccattattat tagagataag ataagaaatg cacgctaaaa agtaaattca 18300 ctacttaaaa atgttaccac gactatttgc agaagtacaa attcagtcaa aatctacata 18360 tgagtaagag aacaaatgtc aaaactagaa tagttaaatt taaatggatt gttagtccat 18420 gataattaca gagaataaag tgaactaaaa aactcggtct taaacaaatt gcgataactt 18480 tatacaacaa aaaagagaag gaccatcatt aggacgttca ttaggaacaa ataaggtcgg 18540 aagtgagtga atggattata aatcaattag agagccaact tggggctgca tagattgctg 18600 ttgcatgccc tgcatcggtt gttgattttg gtaattgtaa ttctgttgat tataataggg 18660 ttgttgcatg ttttgttgtt gctgcatcgg ttgtttataa tatccggtag cttgttgcga 18720 ttggaaagga ttatgcgtgt taccggttgc ctgagcttga atagtctgac cagcactatt 18780 tgtaaatttg gatcctgtgt gttgagtcgg aactctggta agaccaatat taccgaaact 18840 atcagttccc ataggattac cagtggagat tgcttgagca atgttagaaa atcgatcgtc 18900 accagtccga acgggtttca tgggtttagt agcaggagca gtagattgag atggcaagtt 18960 tgaaaattga gcaaaaggat tatttgagcc agtcttcgta ggctccaaac gaggagcaga 19020 ttgttgttgt tgttgctgaa gtattccagt cgattgtgac tgtaaaggac gactgtaagg 19080 attattgttt cctgtatagc cggtagtttg ccgttgtaat ccagtgggct ggggatgaac 19140 ataaccagtg tggttgggag ccatcattgg agcattaggg gtttgaccaa agcctgtacg 19200 ctgaggttgc atgacaggga aagggttgtt ggactcaaat ggctgagaaa agcctgtacg 19260 ttggggttgc atcataccag tacgctgggg ttgcatatac ccagtaggtt ggggattgaa 19320 gaaaccattt tgctgaggtt gaacaaaacc agtacgttga ggctgtataa aacctgttgc 19380 ctgaggttga acaaatcctg tacgctgagg ttgcatgaaa cctgttgctt gaggctgaac 19440 aaaccctgta cgctgaggtt gcataaatcc tgttgcctga ggttgaacaa atcctgtacg 19500 ctgaggttgc ataaatcctg tagcttgagg ctgaacaaat cccgtcgctt gaggttggac 19560 aaatccggta gcctgaggtt gaacaaaacc agtacgttga ggctgcataa atccagtggc 19620 ctgaggttgg acaaacccgg tatgttgagg ttgaacgaac ccagtgtatt gaggctgtac 19680 gaacccggta ttttgaggac ggatgaaacc ggtgggttgt tgttggagga aaccggttgg 19740 ctgtggctga acaggatttc caaagaaatc gacaggttga taagcatttt gctgattgcc 19800 cataaatgcc tgttcttgtt gttcacgttc acgttgatgt ctttgacggg cttcgtcttc 19860 ttctttggaa agttggatgg ccttttgaag ctcagcttcc gaatcgttag ccatgttacg 19920 acgcttggca tcttcttcgg cctgacgttt agactcctca ataacacgtt gtaattctgg 19980 atcattttcc tcggcggagt tgtgttcagc gctcggggaa ggccttctac ttcttcgtct 20040 tgagcgtgag cgaccaggac ggcgagaacg actacgtctc cttgagcgat ggtcacgatc 20100 atcgtcatcg taacgactgg cccgactggg agcgcgagaa agtcgtgatt cctcgtaggg 20160 agcgcgatca tcatcatcat cgtcaaagcg agaggaacgc gttctgtctc tatctctgtc 20220 tctctctcta ctatcacctc ttgcctcctt caaagcgtgc tcgtcctcca acaaagaagt 20280 tatttcttta gccttggtac gaacgttttg gccttgatca tgaccattgt cgtcaacgta 20340 gacaaactca cgcaacgttg tgataatata tatattgtct ttggcccacc gaacaacgtt 20400 ttccgatcca ttgtggagac aatactcgag caaggataac gatttgaaaa catgtcgcca 20460 gttctttcct ttgtcattca gacgacgatc tataatgtcc ataacttcta gcatttcatt 20520 ttggtcatag gttagctctg ctatctccgc catggcagtg ccactgggac cccatgaatc 20580 atttgtagta gcatttctaa ccttaatttg cgtatctgtg tatcccttgg aaaagttttt 20640 tctgcgaatg ttagtaacaa ttcatagaat attgaatgga gtgcatccaa gtacgtgtat 20700 gctcagcacc acatgagaga tgaggtgtgt caatcgggca cgtacgcagc agggaggcaa 20760 atcaagaaaa actagaaatc aatgaagaag aagaagcaaa tttcagatga gatgatgggg 20820 aagatagaaa agaaggattg aacgactttc caagttattc caacttcttt tcactattct 20880 aatgatatga taaaaaatac tagactagaa agtacaaaat tacgccaaca aattataagc 20940 taacgctgaa aatgccatgg ctatggaaag aaatgataga ttgaataaaa tccaattcta 21000 aaatcaccca aagcatgcat ttcatcagct ttttggtcaa ttgaacaaac tttacgctcc 21060 ttcatccccg cttgatgggt tttccgcgta aaaaaatcat ccaaacgcct caattctgcg 21120 acctctttct cttctaccat tcttgggaat tccctcttta cttacactga tcgtacagca 21180 gctttcatgc tcgatctcta actcttgaga tccttcacgg tttaaccacg aatgtctcgt 21240 taatatgcaa attccaaatc cttctgaaaa atcaccaagc tatatgctct atcgtccttc 21300 tttccctact tcggcaacac tgctgatggg ttatggttaa ggttgagggt gccgctatac 21360 tatcgcgata aagcgagacg ggtaggagcg tatgagaata gtcaggatac ggaaacgcta 21420 agtctcgtta atttttcatt aaaaaaattt aaagaaatgg ggtaatattt gacggtaata 21480 gatgatataa gcttataatg agagaaatag ttggccacct cactaataaa tgtttaacga 21540 atttaatggt gtttagagaa gaaggaatgt ggtttagggg aaactacaac agggataacg 21600 caatggagtg cattctccta aactatgtta atgttagcaa cactacacca cgctatgaga 21660 cacagcgttg cgtatcacta tatgtcacgc gttctaatta tatatcgtac catgtatgat 21720 acgatattga gattgatctt aatgataatc tatcaagatc tatattatct gaataatata 21780 aatagagcta ctgctgaacc tcgttcctca gttcagttat aagctatatt agtgataggt 21840 aacattataa cctaattaat acaataccta tactcagttg ctactcatat aacctgtgta 21900 ttgcaatatg atagattgcg aggaaactta ccgcagttct acgtactttt aaaacatata 21960 taaaactgcg tagctgacag ttaaacacta taaagaactt gacagaaaat aatttcgtta 22020 tctttttaca aggatttgta cttattgaaa attaaacgtt ttttccgata tccttaaagt 22080 acgatattta gggatcaatc aatgagcctt tggttgttcg ccctgttgtt tgtttggctt 22140 gggtacagtg ctgtcgaaag taataaatat gtatttttgg ttttcattcc tttctttact 22200 aacaaatgaa taaattttct tgtatacttt tcaattgact ggtaaaagac atatgcatag 22260 tatatctagt aagaataagt tggatgtata tatagtctct agtttttttg cctgtccttt 22320 ctgtagtggg caacgaaata ttggcgctga atccacttca ttttaacaag aaatgtgcta 22380 aatatcatgt gcgataaaaa gaaatgtacc aaaacaaaaa cactgaagtt aatctagagt 22440 tgcttttata tgcaaccaga cagtatagaa cccgaaaaat gcatattaat aaattcggtg 22500 tttgcaggct atgcaaattt taaaacaaat tacaaaacat agatgaatat ttgttgaagt 22560 aagacagtgg ttgaaaattg gtatatatat gaatcacggg tgtatagcgc tagcacattt 22620 cttatagttt cgcatgctag tttcaggagt gaaaggtttt gtaaaatact tttcataaat 22680 atatttgtac ctactgcgca tgtgcaaaca agcgcagttt tcatttattt ggttcatctt 22740 gaatgatgaa ttattgtttt ttttttacat tggcttactg tcactacatc tagtttaaaa 22800 ttcctttttt tatttcattg aattaatttt attttatttt ctatattaat ttttcggggt 22860 tttttttttt tttttttttt ttaatttact ttcagataca attcatccag agtatgtttc 22920 gatatctgtt aatgttttat ttcgtaactc gaatttgcat catttgatca ttattattta 22980 cttcattgtt ttattgaaaa tgtacgattt atgtgtatat tctgactcag acatctctaa 23040 aaacttcttg tcgatttttc aataaaaacc gttaatagcg gcctctaata tgctgtgtcc 23100 aatgtttatc atatatcaaa gcgtttccag ttcattattc aaataaaata ttcttctcaa 23160 tcctgaagct tgggtcgatt ttgcgggaag atatcgacga gagtacaggt ttttgtttaa 23220 gtggaaacat taaccattac tagttgcgat gctgatttgt ctttttcagc catctgttga 23280 ttacagactt atttaaattt tttttctcca taaaaccata aggtgaaagt tttattgatt 23340 tctaattctt ttctactttg cactcttctt ttattatgga tattttactt acccatttct 23400 tctcatttgt tttcaacgca gtagaagaag tacagtattt ggaattgtgt aaacgagtta 23460 atccaacttt cacatattaa gaccccgtta atgatcctta tagctaatag cgtgtcaagt 23520 cataatatca ctaaacatat tgcttcacac agagctccat ttaattacca ttcaaaagta 23580 atagtcgata atcctttctt ttctttaaca taacaattat ttttgaaggt atgtagtaac 23640 agtgctttga agatgttcga aatgcttgtt aaaatgactg aattctgaaa atataaacta 23700 caattctcga ttatggtgtt actcttaaag tgattttctt ttataattaa tacaagcgtg 23760 tggccttata tcaaattcaa cattttcgaa attgtgatta tttttcgcgt ttgtttgttt 23820 gcttccctaa tgtttgttgt tgctttgtct ttctctttca gctaacttcg ttatcacttc 23880 gttttatcag cgtcttcaat taccttttgt ctatttgtgg aattttaatt aacgtaaaaa 23940 tttagttaac ttttgtctag cttttatttc ctcttcttcg tatcttactt ggcaatttct 24000 caattcaatt tgaataatta tctagtatca gtgatttcgc catataaatg catcgtcttt 24060 ttggtagaaa acctcctaca cagcctacgg cttcattaac tgacgccatt gattcggttc 24120 gtatatcttc attcttatag atttttgcca ttgactaata tcttttattt tagttggata 24180 aaagaagcga ctccgttgag gttaaaatcg caaaactaga tgcccagcta tctgttttcc 24240 agcagaaaat tgccaatacg cgtccaggtc ctgggcaaac ggctctcaag caacgagcaa 24300 tgaatgtact tcgccaaaag aaaatgtatg cattctcttt ctcccctttc ttgatgtcat 24360 attactaacg acagcaatat agttacgaaa gccagcttca acaattgcag caacaaagtt 24420 ttaatatgga acaagctgcc atgactacgg aatcgctcaa aaacacaatg gctacggtac 24480 agacaatgca ggagactgca cggcaattga aatctcaaag taaaaacgtt tccattgaaa 24540 aaatcgaaaa gcttcaggac gaaattcaag attatatgga tgcggctggt gaactcaacg 24600 aggttctcgg tcaaaatatg acggacatta acgttgacga ggaggaactg gatgctgaac 24660 tagaggcact tcagcaggag tcctcttggc ttggtgatca aagcacagct gaaaaacctt 24720 cttatttgat gccttccaat gaattaccta actttgtaga tgaggaagtt gctgaacctt 24780 caacagctca gtaagacgaa aattttccta ataggaaagt ttcccttatc ttgttttaat 24840 aatgtatgcg atgtggaatt tgtcatgatt ttgttgtcgt taagtctcat caatcatcct 24900 gtcttatgtg tttatatatt ttacgattat aaaatactaa tcaattcaat ctatcaggta 24960 attttaattg atgtttttca tttaataaat caatatagta agttgtcatc ataggattat 25020 aagcttaatt cttcattttg gcgtaaaaaa agatatgaaa acatccttta taacgtgctg 25080 tccaacggta acgctaggta atttgaagaa actaacaata tatcgaatca ggcagacatg 25140 ggtttttgag cacttaggaa ataattacaa gacaaaccaa gcccactcga tcctggcttg 25200 tcaagtgtcc actgctgttt caaagggttg taacaaacac cacgtatatc attaattatc 25260 caattctgtt ccttcaggaa atttgatagt tcgtcggcac gtataaactt ttcaaaagta 25320 tgtgtcccga caggtacgat gcgaagaaca tgttcggcaa gcgtaatcgt taacaatctc 25380 gccaagagag ttcgtgatat agttgacagt acgagtcgcc cgttaggttt cactttttcc 25440 attaatgaaa ataaaaaatc tctaggttgt tcgacatgtt caagcacctc catgcacgtt 25500 accacatcaa aagtagtagg aagttgtgaa ccttcgactg atccatgaat atactctaac 25560 cgaccattca aaacaggatc aagactggca tgtttttttg caacttcgat agccattgga 25620 gaagcatcaa ctgccgtcac tgaagcaccc aacctggcca tgctttcact caagatacca 25680 cccccgcaac caatgtcaag aatcttctta ccagaaaagc agttacgctc acgaaatact 25740 tcagtcataa aatccaaacg agtagaattc attaaatgta acaatcgact tccaccgtcc 25800 caatcccacc aagttttcgc cagttcattg aagtggtcta cttcatttac tgacactgaa 25860 tgatttcgct gttgacttag aaatccctgc ctaaccaatc tggtatagga ttttacattt 25920 tttactttat tgagaatgtt cattgagttc atactacttc atttggctcc ttcttgttgt 25980 ttacagtctt caatgtcata tcattcttat ataactaaaa tcctaggacg aattcgttat 26040 ataattttac ggtattgtaa tttatacgtt ggtcaatcga gcatgtcagc tacgcagttt 26100 gatatctgtt taatgataca ttggactgcg atgagtttta cttgcgatct acaatgtagc 26160 ggtatgcggt gtgttaagta acaatgtatg tttattgtta taagaagtct gttagtatcg 26220 gtcaccgata tagctcataa ctgaattgag gaacgagatt cagttgtagc tctatttata 26280 atcttcctaa aaagttgtta tcaacgggtg tctatgtata tagacggata gttacccgtg 26340 attatcaata aacggatctt agctagtatt ccaacatatg acatatagtg atacgcaacg 26400 tagtgtatca tagcgtaatg tagtattgct gacataccgt agtactaaac actcactatt 26460 gcaatgtgtc attataatca ttacgataac aaaccatcgt tctgaatcac aatattttat 26520 tatgctattc attatttcgt aaacattgaa atttgtttgt attaaagtaa accattaaac 26580 aaaaggaaaa aatgataatt aagcttgatt cattaagaat caagatgaag gagaaatgaa 26640 tgcaataaac gaaaatgaaa ttgtgaattt aacaaggtgg aacaacgagt tttccaattt 26700 cattagttaa tttaaagttg tcgtaaacaa gttaaaccat tattgtttgt agcgtagagt 26760 accattaaaa aagacaaata attagactcg catacataat aaataaagac tcagtcctca 26820 atgcacatta tccaacatcg tagaatgcat tggttggcaa tttttggtaa ttgaaagaat 26880 gagttaagct tatatctcac aaacttataa ggcaagagaa taattaaagt atgttggtgc 26940 ttatttttaa aaaacgccgc agcttctctg cgttggtgat tttggtaaag aggttttcca 27000 actggagcga caaccacatt aataaagcaa ttagacttcg ctttcaacat ccatttctcc 27060 caagggaatg tcattattat cgttggcacc tctaaacgca tttcctatcc gcccaattgc 27120 atttcctatc cctccaaatg catttcctat ccctccaaat gcattcccta aacctcctag 27180 tcgggtaagt aaaaaatcat tcatacagtt ggttgaatac acatacctag gaaagaagct 27240 ataccattcc cgataaattt gggcatcctt ttgagagcac ctggacgttc tggtatggtt 27300 agagtaaatt acaggaatat ataacgaacc catttcgtaa aagaaaagaa aatttcctat 27360 aacaaagagt gaagaggctt caatttcgta gcctgtcgcg tcgatatgtt tatcaaataa 27420 atacatcaaa cctttcgtta caataacgac acaactttgt acacccagca cttgaaacaa 27480 accaaaaagc atatgcttga gtgtccaaat tggaatacaa actgtatgtt agcgtttagc 27540 aagataattt cacttaccaa gcaataaaat gaaaaataaa gcagccgaaa tactgcatgt 27600 ggaacagatg agtgccttat ttaagtttag tctaccatcc ttgacgcaac caaagagtat 27660 aaaacaaatg actacccatg cgagccagat tgtaaccacc aaatcttttt ttgagttata 27720 caaaccgacc gcaattacct ttacacattt tgccaagaaa actgcagtca cctttacaca 27780 ttttgccaag aaaactgcag tcacctttac acattgtgcc aaggaaattg cagtcacctt 27840 tacacattgt gccaagaaaa ttacagtcac ctttatacat tgtgccactg cctgggtcca 27900 agtttcaaag aagcctaatg agttagtgaa tggacgtatt aacaacttca tgcatagctt 27960 acagaaaata gcaataaaca ctattggaca tgttatacca attgtgacgg agaaagctac 28020 cttgccgaat atcgacttct ccaacgggtt tacacaaacc catgcagtaa aaaagacaac 28080 aataactgca agaactgata ttagtagtct cagaagggaa tatatatttg gatgtgaatc 28140 tttgaattct tgtcttcttt cgacattggg atttgcaatt tctgtaggtc ctgtacttga 28200 atcctcagat acagttttaa tatatttcca aatttctgaa agcattaata aaataaataa 28260 cttttgaaat ttggtttttt ttttttttta aaatgatgta gaaggaagaa agtgtgtgcc 28320 ctgttagacg aatttatgct cgtaatatgt caagttgtaa acaaacaaat acaacaaaaa 28380 cattgtaaat caaaacaaac agacacagca aataatcctt gacacactca attctttatc 28440 ttatccacca acaacacaac acttacctga atatggaggc aatgtgctcc catcttctga 28500 attgtattct gggagaggac ctttttccaa atcaatttca ttatcgtttt ttgtactcaa 28560 ttcatccata gacgacctca agggataatc tttattcttc atttcttaga aacaatctat 28620 tattgaatga tatacacaca aatagttcaa ttgctgtgat tgcgacaaac gaaacagcga 28680 aatcaagaat attcgctctg tagtccaatt ccaatcgctt taaagacttt ttaacaaaat 28740 aataaaattg ttcaaacaaa tttccaacta attccttcaa acaatggcat aaaaaaagaa 28800 gaacgaaaaa actgaacgag gcagtggatt gcttctgaca catttattct gtcactgcct 28860 ttttattaag ttagcttgag attccttcat gttagctacg cagtttggta tctgatttaa 28920 ggatacgtag aactgcggtg agttttcctt gtgacctatt atattacatt acacaggtta 28980 tatgagtagc aactgagtat aggtattgta ttaattaggt tataatgtta cctatcacta 29040 atatagctca taactgaact gaggaacgag gttcagcagt agctctattt atattattca 29100 gataatatag atcttgatag attatcatta agatcaatct caatatcgta tcatacatgg 29160 tactatatat acatgtgaca tatagtgata cgcaacgtag tgtattatag cgtagtgtag 29220 tattgctgac acaatccaca ttatttcgca gctcactatt tgataaacaa tgaaaagacg 29280 aagctagaag taggtaagat tagtatatgt tatgttacgg agcataatta taaacacgga 29340 ttctaataca atacaatgga gattcatgta ctttactttg atcttaattt ttaaaatttg 29400 tgacaattct aatgttctga cgctagatca ttagaggcac aaatttttgt ccgtagcctt 29460 actaaacagt atagacactg atgtttgtta ttcagaattt atgaagaagc aacagaagtg 29520 gtgttatatt caaatgaata gcattaattg gtaatttgga acgtttctta atcagtgaaa 29580 tacacatttt tttttacgaa gtatgaaagt gaaaaatttg tgcaaagaaa ataaatgcag 29640 acaagttcat taatatttga accaatgcat tgtagtttta gaaattgttt gactgcattt 29700 tctcatatga atgtgtaaat aaggaaatga tcgttttgcg atcctcatat acattcaact 29760 cttcatttaa ttctattcaa cgagatcaaa aaaaattctt gtatgccttc atcacataga 29820 ttgaagattt tgacgcaaag tttctaccga agctggatca aaatcatcct ttgcaacact 29880 tgtactaagt gcaacattac tttcaagctc ttcccctatg tcttgatgtt gcttgcggat 29940 taattccaag gaatcgtggc ctaggacaag cttttgaggc ggcctgtcga gtttggcaat 30000 gctatataac aactccgcag ctttgttcgg gtcagtttcc tcgcagccat gatagttttc 30060 ccaaaatggt cgccaagacc tgtcattttc gtaggctgga tgaggttttg cccattgcat 30120 attagaggaa gcccattctg tttgcatgcc acctggctgt acaatagtta tcgcaatgtt 30180 ccaattcgga tctaactctc tcataattgt ttgcgaaagc ccttcgacag caaatttgct 30240 agcattatac atgcttaaac acggagatgg gtaataacct gcgactgacg aaatttgtaa 30300 aatacgccct cctttaccgg attcgcgcat gagattcaac gcttctttgg taatgtatgc 30360 aactccccaa aaatttacat tcatttgacg atgcatttcc tcaatgttgt atgattcaaa 30420 ttcgccaaca aggccatacc ctgcattgtt gatcactatg tctacgtttc caaatcgcct 30480 ctttgcatct ttgaaagcgg tttcaacaga cttcacatct gtaacatcta atttgagctt 30540 taataatttt gaatgctcga tggttattgt gtcgggagca cgagaacaag ctattacatt 30600 ataaccttgg gccaatccaa ctttcaccaa tgcatagccc aatcctttgg atgacccagt 30660 aatgagtaca gtagaaaacg tagatttcat tgtttcttat gatcgtgttt cgtcttttga 30720 gacaccacga ttgtacaatt aaacaatttt tttgctttct caaccaagcc cgtttttacc 30780 cgattactgt tgtagtaagc cttttcaaat ggtattcgag tagttcacaa tcgtcgcgta 30840 acagacaaac cctgattctt ttgagcttct taacaatgaa ttgcttaact taactctcta 30900 atccacttgc tggatattgc ttttcctaag tcttcatttc tcgaagtgaa agtatgatga 30960 tgttgttggt gttcggatgt ctgtaaacac ttttcgtttc tactatccgt agctcatcgt 31020 ataaaagaat cctataaagg gatatagata ggctcagtaa tgtagtgctt gcgctacgtc 31080 tcaaaactca ccaccatacc gctgtctcaa tgtcctgaac aatttgtgaa ttaagttagt 31140 taactcttaa agttgtaaga atacaatatg ttcttccgga tactgtatac tcttattgag 31200 ggcaatggag tcggattcct atagccggat cctggttttt ttacatgcag tgagattaat 31260 gtatcgttag catagaagac cgatttgaaa caagaagtgt taacttttta actttacgaa 31320 atttgctgtt tgtcatttca aggttgcttc tttagttgat actggtattg aaaatattta 31380 aaaaaaaatg ctgtgcgatt cgtcagaatc agtttcgttt tcatccatat ctaaagaaga 31440 agatacacca atcgctcgcc ttttgaaaaa cgcaaaagaa acaccagatc atcggtttat 31500 ctccgtgtac aatgaacgtg gaattgttgc taaatataca tatacagaat tacttcgtcg 31560 tgttaacaca attgctaaat tttgtgatga tttaggcttg ggaaagacag ttggaataca 31620 tatgggacac gagttggatt ttctgtgttc tatatttgct ttatgggcta ctggacgaac 31680 ctgcgttatt tttaaccaaa tttggtccca gcaagttgtt cgtgtacttg ttaaacgttt 31740 gaatatttct gatttgcttt atcatgaata taagcccaag tttgaggtgg acaccttaaa 31800 tgctacatcc ttggcttcgc tgccgctgga tatcgatgct ccttgtattc gagctggatt 31860 agagccggaa gtcgctctta ttaaccattc tagtgggtcc acaggagtcc ctaaatccat 31920 gccatttctc atgaagaaat atgctttggg ttatgactat ggaactcctg aatttatgaa 31980 tcatctctcc actccaatgg taatggctac cagctttgct ttaacaacct tgagttggat 32040 taatgccttg tattgtaatg ggaacttact gtacccatcc tcttcgatat cggctacttg 32100 cacttcagag gctgaacggc ttgcttggaa tgtttactat gctcttcgtg ctggatgcga 32160 acgtttaatt attttaccca atctccttgt tctaactctc caaataatgc ctgacaagga 32220 agaatgcttt cctgcttgta aactagtagc agcaggcggt gaaatggtcc ctgcaaacat 32280 gtatcataca tgcaaacgag tattaccaaa tgcgaccatt tatccacagt atggtactac 32340 tgagtcggga ttggtttcat ttttggctta caatgggaaa gacacactgc ataacaaaga 32400 gcttgtctat ttccctggta aaaccgttaa aaaactaatg ttagtcactg aggataacga 32460 agctgttcct gaaaaaattg gttgcgaggg ctttgtttgt gttgtgaccg atgtacaatc 32520 ggagccttat gtaggcgatg atgctgaaac tattcaatcc cgtaattcta cgtttataaa 32580 ttatgatggt caaccagcag tgcgatttgc tgacttggcg gtttggaatt cttataaagg 32640 aaaattggga atcaccatta aaggccggtt aggaagacgt gtcaaaagaa atggtgtatt 32700 ctttgatttg aaatattttg accaagttgt tgtaggattg aaggaggtaa aagacgcttt 32760 ttctttcttc atattcaatc gctttgtatt ggtgtatgtt cctgcatata atggtgtgga 32820 tcctgtaaca ctaaagcaaa aattgaacaa agagctccga gatcaccacc ttttctcaag 32880 ttgctttccg cttgctgata taccgcgtaa cgctgcagga aaagtggatt tgaagtctat 32940 cgaaacttac gcatctaaat gcctttccgt agaagatcag cgcttacctg ttttattaaa 33000 ccctgtggct attgaaatca gtaaaattgc ttcaaaaatt ctccaaaacc caagcttgga 33060 aggaaaggac gcacctcttt attcctgcgg tttagattcc attcattctg tgagattttt 33120 tcatgctatt caatcccact ttcatcttga aggcccaatt cgctacaata tgaattcaaa 33180 ttgtacccct aactcgatag cctctataat tcaaaagaaa agttacaacg tatcgtcaat 33240 cacctatgaa cttttaaatg aagatgcatg cgctttatca cgtaccattc ccaagttaag 33300 tattctgcct accaatggtc aatatttctt gttaactgga gcaacgggtt attttggtcg 33360 tcgttttttg gaatatctag taaagttgaa tataagtgtt gtatgtctag ttcgagagtc 33420 ctctgatgaa gctgctaaag aaaggttaat atcacttgtt cctagtcttc gaatttcgag 33480 tgaaaatata attgtatggg cggctcatgt agaggagatt agatttgggt tggatgatgc 33540 aaaatgggag tttctggtgg aaaatgtttc ccgaatctat cacatggctg cggaagttca 33600 ctggatgaag tcgtatcaag aacttagacc agcaaatgtt ttggggacta agactgtttt 33660 ggaactgagt gtgatgggac ccaaggctct ttactttatc tctggaggtg gacaacagga 33720 agtagagctt gacgatgata ctcaatctgc taaagcatct ggatatgcac tatccaaata 33780 cgttgctgag ctcttgtgtc gaaagattag cgatttagga catcccttaa tatatgttat 33840 tcgtccagga tttattatag caaacgatgg ggaaatttta tcgagagatt tcttttggcg 33900 tttcgtcgcg acagctttac gaatgggtat ttggccacaa agcgatgaat cacaatcttt 33960 ggtattccac atttcaacaa ctgatgcatt gtgcatgacg ctgactcaaa tattggagaa 34020 agaagctgat gcgtatgctc cacttttggc ttatgataag tttgacggtg atgagtttgc 34080 ttgtatttgt gaatctatga aaaacgttaa gctagacttt gttacattgg aggattggtt 34140 gaaggcactt gaaaaagatg tcgatgaaaa aggtgaagac catcctctat ttgctcttca 34200 gcatgcaacc aagtttgctc tgaaaagcag catgacacca agcaacgggc taaggaatat 34260 ttatcctttg agtgaaacct ttctaactaa ggaagccatt gcaaacgggc tggagaatct 34320 atacattgaa tagcttagtg ttagcactga tttgtccttt ggaacagagg ggccaaagag 34380 atgtacaaaa attaaagatt ggtttagatg tatcagtaaa tggtttctaa ctactaatct 34440 aaatctaagt gtatattaat tatgctgcaa ttctttgttg atttatttac aatatcaagt 34500 aacaagtaaa gaagcaagct tcatgttacc tgacctactg atcctcacta cctttataac 34560 gagtgagaag tttgaatgta tcacagttgt aaacccacaa aaaaaattta aaaaagcgtc 34620 tagcagcagg atcaaataaa aaaacattta attgtataat tttagaagat ttagcttcta 34680 agggaaattg tttatttgtt caatctactg tgaagtttgg gatagttgaa aagttttgga 34740 gaagataatc ggggattcct ttttggtata gtagcaatgt cttcgtcaag aagcggtgaa 34800 caccgtcgaa attatgcgca aggccgaaat tacgaatcca gtcgctcacg cggtgatcaa 34860 cgagacaggg attatcgtga atatcgtcga aattatagag acgagagaag tagtagacgt 34920 tacgaggatt cacaacgtag agattacagt ccagctagaa gacgcgatcg ttacgaaagg 34980 catcgagagt ctgtgcgaga ggaaagccct aggcgtccag tagagcatga acgaaactgg 35040 caaccggagc tgaagcatgg ccgagaaaga tttcgagagc gagactatga aggtcgacgg 35100 gatcggaagg aacgaagaga cggtgtctca cccttttctc ctgaagggga ggggttggaa 35160 aggaaaagag agcatgaaaa attgcaagca ccatctccaa aagaagagga agaaaggcct 35220 gttgatcaag gcgacaagat ggatggagta aaggaggata aggatgggtc tttggaagta 35280 ggaaaaagcc acgatgcgat gacgaggaca aagagcgctg aggaagaaat tgtggaacaa 35340 gaggatgaag cgacggcaga gatgaaacgt attatgggat tttcgggatt tgacacaacg 35400 acggggaaga agcatggaga cgtgggccag gtgtacaagc aaaagaaaac caagtataga 35460 cagtatatga accgacccgg tggatttaat cgtccattgg ataatgaata gaaagtcaag 35520 aaaggaggga aggtgtgtat ggatagaact ctttaatgaa tgatatgcaa gcagaatccg 35580 gaaaaaagta gttgtaaagg gaaaatgaag agaggagtag tttagttata aagagaacat 35640 gaaaagagat gtaaaaataa aaaaatgttt aatttagtaa agtcgacgaa aaaagttgaa 35700 atgtaaacga gagaagagtt gaatcaaaat gttcgtccta aagaagttgc gattttggaa 35760 tggtgtattg tttacttggc atgaactttt gccatgcatt taacgcaatc ctgcgtgaat 35820 atcgctagat aaaaacctta tattaagcga gagagataga aggaccccgc gaatattgga 35880 aattgtttgc atgtgcgcaa tcaagccgaa tccacttttc ttacagtaag agaaggaagc 35940 gtgtgtagag tgtataaaca agagaaatga aataaaaact gtgctaaagg aagcatttgc 36000 aaagatgtgg gacggatggg ccagtttatg caaattcgtt aaacaaagct ttgctttctg 36060 ctatggcagt aacaatggcg atattaatga ctgttgattt tgatgcctaa tggcttgatg 36120 aaacacgaca catgatcata aaccgtgtat ggtattattg tatattgtat ggtattgtgt 36180 attgtatatc gtactgtgtt cgaagagtat aaggaaaaaa tggtagagag gaaccaatta 36240 atgttttact gtaaagtagc ctgcattacg ttatatttga taatgagctc gataaatggg 36300 cttaatctat tttcttgaag gggagaatgg gacagatgga tggaaagatt tgaaaataca 36360 tagtgttggt tgaatttgca ttgggaggcc ggcggagcat gcgaaccatt atagaatagg 36420 cagtatgaaa atttagcaag cgatagctca agtttgcatg atcgaatgag ttatccaaaa 36480 aataaactgg agtattgttg aattcagttt tgagcaaccg aattcgcagt accttcttac 36540 agtacctcct cacagccaag tttctaccct agtagagagt atccagtttg tcggtttgtt 36600 ggttgcgaaa ccagtatgga cgatgttggt tgtcagatta agcagtgcaa gttttgcagc 36660 ccatgttggt aagtgaagag agacaaatag gatgacaacg agcggcaggg cgagagcgag 36720 gcaaggatga gagtaggaag agggaagaag gacaaaaatt tgaaaaggat gtgaatgtga 36780 atgtgattga gttggatgaa aatttcgtct ttacatttgc ccgttataaa cgagtgttga 36840 attattccta tactacagat ttatatatct acatgattcg attcctacag gattgtaaac 36900 ccacatgatt tgtatacact ataatttgta tatacctagt aatgattctt ttattctcca 36960 ctccactaat atgaaaatat tcttgtatgg ttatccttat gtgatgaaat atcttttaaa 37020 cgaggtccac gcggatctcc atatcagata aaaaaaaata ctacgacaaa agaaggctaa 37080 aggaataggg ttgagtgcta ggtggatggt acgatgttgt ttgccctaat acggcatact 37140 actagggaaa tgttgggtgc ataggcctac aatgttagtc gtaagagacg agacgagacg 37200 agacgagatg aacgaaataa cccgctccca actctataaa gggttaagga tagagagaaa 37260 ttgagtggta cgtttggtgt gccgtttgtc gagccgtcga ctgctagtaa tattgtcatt 37320 gtgattacca ttgccattgt caatgtcact gctattgcta ctgacactgc cgctgtactc 37380 ttcttccgat gtagctttat ttacattgta tcggaaaccg tccacaccca tggtcgagag 37440 ctgtgggtga cgcagacatt cgaatggcat gccctacaac aactaagaaa atggctatca 37500 tgcggaagct ggtgagaaga acagcatcgg gacaagggaa ggaagaacaa agacaaagaa 37560 aacaaaagaa agcaattgaa aacaaaacaa aacaattttc attccttctc ttatcattcc 37620 ttttcttttc ttttctctca ttcaacgcac tccatcgtat ccgtattcct cttatttttt 37680 ctctttctct atatccattt ctttctctct aggtgtgtcc tctctctctc ttcaatttct 37740 ctactccgca ttccaacgca tccttccccc aacctcccat ttcctcctta cggcccgata 37800 gcgatcgtct ttccctcgct atcactcgct accggcccct cctctgcacc gtaacctcct 37860 acgtatttac catatcataa agttttttcc gacgcttatc gctgaccccc tgtcgccctc 37920 ctattggctt ccggattatc ttcttgtcca taaggtgatc 37960 //