ID SPCC13B11 standard; DNA; FUN; 9999 BP. XX AC AL032681; XX SV AL032681.1 XX DT 29-OCT-1998 (Rel. 57, Created) DT 12-DEC-1999 (Rel. 62, Last updated, Version 4) XX DE S.pombe chromosome III cosmid c13B11. XX KW adh1; alcohol dehydrogenase; KW glutathione-dependent formaldehydedehydrogenase; KW hydroxyacylglutathione hydrolase. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-9999 RA Purnelle B., Goffeau A., Lyne M., Rajandream M.A., Barrell B.G.; RT ; RL Submitted (14-OCT-1998) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and Unite de Biochimie Physiologique, Universite RL Catholique de Louvain, Place Croix du Sud 2/20, B-1348 Louvain-la-Neuve, RL Belgium XX DR GOA; O74540; O74540. DR GOA; O94250; O94250. DR GOA; P00332; P00332. DR SPTREMBL; O94249; O94249. DR SPTREMBL; O94250; O94250. DR SWISS-PROT; O74540; FAH2_SCHPO. DR SWISS-PROT; P00332; ADH_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c13B11 overlaps cosmid c162, EM:AL023860, at its 5' end, and CC cosmid c777, EM:AL031532, at its 3 end. XX FH Key Location/Qualifiers FH FT source 1..9999 FT /chromosome="III" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c13B11" FT /map="IIIR" FT misc_feature complement(1..2205) FT /note="nominal overlap with cosmid SPCC162, EM:AL023860 S. FT pombe chromosome 3" FT CDS 2512..3564 FT /db_xref="GOA:P00332" FT /db_xref="SWISS-PROT:P00332" FT /label=adh1 FT /note="SPCC13B11.01, len:350" FT /gene="adh1" FT /gene="adh" FT /gene="SPCC13B11.01" FT /product="alcohol dehydrogenase" FT /protein_id="CAA21782.1" FT /translation="MTIPDKQLAAVFHTHGGPENVKFEEVPVAEPGQDEVLVNIKYTGV FT CHTDLHALQGDWPLPAKMPLIGGHEGAGVVVKVGAGVTRLKIGDRVGVKWMNSSCGNCE FT YCMKAEETICPHIQLSGYTVDGTFQHYCIANATHATIIPESVPLEVAAPIMCAGITCYR FT ALKESKVGPGEWICIPGAGGGLGHLAVQYAKAMAMRVVAIDTGDDKAELVKSFGAEVFL FT DFKKEADMIEAVKAATNGGAHGTLVLSTSPKSYEQAAGFARPGSTMVTVSMPAGAKLGA FT DIFWLTVKMLKICGSHVGNRIDSIEALEYVSRGLVKPYYKVQPFSTLPDVYRLMHENKI FT AGRIVLDLSK" FT misc_feature 2527..3552 FT /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding d FT ehydrogenases" FT misc_feature 2713..2757 FT /note="PS00059 Zinc-containing alcohol dehydrogenases FT signature" FT CDS complement(4555..4971) FT /db_xref="SPTREMBL:O94249" FT /label=SPCC13B11.02c FT /note="SPCC13B11.02c, len:138, questionable ORF" FT /gene="SPCC13B11.02c" FT /product="very hypothetical protein" FT /protein_id="CAA21783.1" FT /translation="MHFTLFLYFDAIRHANQRRWCHECTIKIFRRSFDIARHTVHLCVR FT KIFSLHPLTETDFLPNELRSEEDQTLIGIFWFLPPIIEGEDERSRFPRRSMSENHLIIT FT KKSLHNVASKDYIRGSHVPCFQPYEDVYELNIEE" FT CDS join(complement(7096..7214),complement(6506..6911), FT complement(6195..6440)) FT /db_xref="GOA:O94250" FT /db_xref="SPTREMBL:O94250" FT /label=SPCC13B11.03c FT /note="SPCC13B11.03c, len:256, FT SIMILARITY:Schizosaccharomyces pombe, CAB57337, putative FT hydroxyacylglutathione hydrolase, SPAC824.07, (256 aa), FT fasta scores: opt: 1005, E():0, (55.9% identity in 254 aa)" FT /gene="SPCC13B11.03c" FT /product="putative hydroxyacylglutathione hydrolase" FT /protein_id="CAA21784.1" FT /translation="MSFQILPIPMWVGTQDNYAYLLLCEETRQAAIVDPAEVNVVMPIL FT KKKLKNKEIDLQAILTTHHHADHSGGNLNLKKEFPHVTIYGGSDQNGVSHVLQDKETLR FT IGNVQIEALHTPCHTRDSICFYAHSSNEHAVFTGDTLFNAGCGRFFEGTAAEMHIALNA FT VLSSLPNNTVIYPGHEYTKSNVKFASKHLQSEALNHLEGLCNHNQFIAGHITMGQEKQF FT NPFMRVTDPELQKHLGLNDPIKVMDELRTLKNQG" FT misc_feature complement(6441..6456) FT /note="ctaacaagtttcctag, splice branch and acceptor" FT misc_feature complement(6500..6505) FT /note="gtaagc, splice donor sequence" FT misc_feature join(complement(7096..7154),complement(6506..6911)) FT /note="Match to lactamase_B , Score 33.12" FT misc_feature complement(6912..6926) FT /note="ctgacaaagctccag, splice branch and acceptor" FT misc_feature complement(7090..7095) FT /note="gtaagt, splice donor sequence" FT CDS join(complement(9723..9749),complement(8568..9683)) FT /db_xref="GOA:O74540" FT /db_xref="SWISS-PROT:O74540" FT /label=SPCC13B11.04c FT /note="SPCC13B11.04c, len:380, SIMILARITY:Candida maltosa, FT FADH_CANMA, glutathione-dependent formaldehyde dehydrogenas FT e, (381 aa), fasta scores: opt: 1813, E():0, (68.8% identit FT y in 381 aa)" FT /gene="SPCC13B11.04c" FT /gene="SPCC777.01c" FT /product="probable glutathione-dependent formaldehyde FT dehydrogenase" FT /protein_id="CAA21785.1" FT /translation="MQQSPTAGKIINCKAAVAWQPAAPLSIENVQVFPPRVHEVRIKIV FT NSGVCHTDAYTLSGKDPEGLFPVILGHEGAGIVESVGPQVTTVQVGDPVIALYTPECKT FT CKFCKSGKTNLCGRIRTTQGKGLMPDGTSRFSCNGNTLLHFMGCSTFSEYTVVADISVV FT AIERLAPLDSVCLLGCGITTGYGAATITADIKEGDSVAVFGLGSVGLAVIQGAVKKRAG FT RIFGIDVNPEKKNWAMSFGATDFINPNDLQSPIQDVLIHETDGGLDWTFDCTGNVHVMR FT SALEACHKGWGQSIVIGVAAAGQEISTRPFQLVTGRVWRGCAFGGVKGRSQLPDLVKEY FT LDHKLEIDKYITHRRPLKEINEAFTDMHNGNCIKTVLSIP" FT misc_feature complement(8616..9728) FT /note="Pfam match to entry PF00107 adh_zinc, Zinc-binding d FT ehydrogenases" FT misc_feature complement(9456..9500) FT /note="PS00059 Zinc-containing alcohol dehydrogenases FT signature" FT misc_feature 9527..9999 FT /note="nominal overlap with cosmid SPCC777, EM:AL031532 S. FT pombe chromosome 3" FT misc_feature complement(9684..9696) FT /note="cttattaaaacag, splice branch and acceptor" FT misc_feature complement(9717..9722) FT /note="gtaagt, splice donor sequence" XX SQ Sequence 9999 BP; 2856 A; 1993 C; 1887 G; 3263 T; 0 other; tggaatggtg tattgtttac ttggcatgaa cttttgccat gcatttaacg caatcctgcg 60 tgaatatcgc tagataaaaa ccttatatta agcgagagag atagaaggac cccgcgaata 120 ttggaaattg tttgcatgtg cgcaatcaag ccgaatccac ttttcttaca gtaagagaag 180 gaagcgtgtg tagagtgtat aaacaagaga aatgaaataa aaactgtgct aaaggaagca 240 tttgcaaaga tgtgggacgg atgggccagt ttatgcaaat tcgttaaaca aagctttgct 300 ttctgctatg gcagtaacaa tggcgatatt aatgactgtt gattttgatg cctaatggct 360 tgatgaaaca cgacacatga tcataaaccg tgtatggtat tattgtatat tgtatggtat 420 tgtgtattgt atatcgtact gtgttcgaag agtataagga aaaaatggta gagaggaacc 480 aattaatgtt ttactgtaaa gtagcctgca ttacgttata tttgataatg agctcgataa 540 atgggcttaa tctattttct tgaaggggag aatgggacag atggatggaa agatttgaaa 600 atacatagtg ttggttgaat ttgcattggg aggccggcgg agcatgcgaa ccattataga 660 ataggcagta tgaaaattta gcaagcgata gctcaagttt gcatgatcga atgagttatc 720 caaaaaataa actggagtat tgttgaattc agttttgagc aaccgaattc gcagtacctt 780 cttacagtac ctcctcacag ccaagtttct accctagtag agagtatcca gtttgtcggt 840 ttgttggttg cgaaaccagt atggacgatg ttggttgtca gattaagcag tgcaagtttt 900 gcagcccatg ttggtaagtg aagagagaca aataggatga caacgagcgg cagggcgaga 960 gcgaggcaag gatgagagta ggaagaggga agaaggacaa aaatttgaaa aggatgtgaa 1020 tgtgaatgtg attgagttgg atgaaaattt cgtctttaca tttgcccgtt ataaacgagt 1080 gttgaattat tcctatacta cagatttata tatctacatg attcgattcc tacaggattg 1140 taaacccaca tgatttgtat acactataat ttgtatatac ctagtaatga ttcttttatt 1200 ctccactcca ctaatatgaa aatattcttg tatggttatc cttatgtgat gaaatatctt 1260 ttaaacgagg tccacgcgga tctccatatc agataaaaaa aaatactacg acaaaagaag 1320 gctaaaggaa tagggttgag tgctaggtgg atggtacgat gttgtttgcc ctaatacggc 1380 atactactag ggaaatgttg ggtgcatagg cctacaatgt tagtcgtaag agacgagacg 1440 agacgagacg agatgaacga aataacccgc tcccaactct ataaagggtt aaggatagag 1500 agaaattgag tggtacgttt ggtgtgccgt ttgtcgagcc gtcgactgct agtaatattg 1560 tcattgtgat taccattgcc attgtcaatg tcactgctat tgctactgac actgccgctg 1620 tactcttctt ccgatgtagc tttatttaca ttgtatcgga aaccgtccac acccatggtc 1680 gagagctgtg ggtgacgcag acattcgaat ggcatgccct acaacaacta agaaaatggc 1740 tatcatgcgg aagctggtga gaagaacagc atcgggacaa gggaaggaag aacaaagaca 1800 aagaaaacaa aagaaagcaa ttgaaaacaa aacaaaacaa ttttcattcc ttctcttatc 1860 attccttttc ttttcttttc tctcattcaa cgcactccat cgtatccgta ttcctcttat 1920 tttttctctt tctctatatc catttctttc tctctaggtg tgtcctctct ctctcttcaa 1980 tttctctact ccgcattcca acgcatcctt cccccaacct cccatttcct ccttacggcc 2040 cgatagcgat cgtctttccc tcgctatcac tcgctaccgg cccctcctct gcaccgtaac 2100 ctcctacgta tttaccatat cataaagttt tttccgacgc ttatcgctga ccccctgtcg 2160 ccctcctatt ggcttccgga ttatcttctt gtccataagg tgatccatgc ttcctgaaga 2220 ttcccgaaat gtgtccactt tggcggggaa tcattccatc cacttctttc tctctcgctt 2280 tcctcattcg gcgctcccct tccgcgtctc attggtcttc cgctccgttt ttgctttgcc 2340 gatgttactt ggggagaggt gcgataatcc tttcgcaaaa actcggtttg acgcctccca 2400 tggtataaat agtgggtggt ggacaggtgc cttcgctttt ctttaagcaa gagaattcca 2460 ttgtcttgac tatcacaaac ttttaagtct tttctttttt ctaaccacat aatgactatt 2520 cctgacaagc agttggctgc cgttttccac acccacggtg gtcccgagaa cgtcaagttc 2580 gaggaagtcc ccgtcgccga gcccggtcaa gacgaggtct tggttaacat caagtacacc 2640 ggtgtctgcc acaccgattt acacgctctt caaggtgact ggcctcttcc cgccaagatg 2700 cctttgatcg gtggtcacga aggtgctggt gtcgtcgtca aggtcggtgc cggtgtcact 2760 cgtcttaaga ttggtgaccg tgttggtgtc aagtggatga actcttcttg cggtaactgc 2820 gagtactgta tgaaggctga ggagaccatc tgccctcaca ttcaactttc cggttacacc 2880 gttgacggta ctttccaaca ctactgcatt gccaatgcca cccatgctac catcatcccc 2940 gagtccgttc ccctcgaggt tgctgctccc atcatgtgcg ctggtatcac ttgctatcgt 3000 gccttgaagg aatccaaggt cggccctggt gagtggatct gcattcccgg tgccggtggt 3060 ggtcttggcc atcttgccgt ccaatacgcc aaggctatgg ctatgcgtgt tgttgccatt 3120 gatactggtg atgacaaggc tgagctcgtc aagtcctttg gtgctgaggt cttccttgac 3180 ttcaagaagg aagccgacat gattgaggct gtcaaggctg ccaccaacgg tggtgcccac 3240 ggtaccttgg tcttatccac ctcccccaag tcttacgagc aagctgctgg ctttgcccgt 3300 cccggttcca ccatggtcac tgtttccatg cctgccggtg ccaagctcgg tgctgatatc 3360 ttctggttga ccgttaagat gcttaagatc tgcggttctc acgtcggtaa ccgtattgac 3420 tctatcgagg ctcttgaata cgtttcccgt ggtctcgtca agccttacta caaggtccaa 3480 cccttctcta ctcttcccga cgtctaccgt ctcatgcatg agaacaagat tgccggccgt 3540 atcgtcttgg acctttccaa gtaagggaat gagaatgtga tccactttta attcctaatg 3600 aatacatgcc tatagttctt ttcttttgtt ctttatgtcg tttttcgatg gtacggccgt 3660 tgtcaatctc agtttgtgtg cttggttgca gcttggtttc aaatctgttc atctcatgaa 3720 tcttttacca tttcaccaca cgtttatacc attctctcat agaatcttca tcaaaccatc 3780 tcggggttag agtggaaaga aagtcttgtt cttttatttc cttttttcca tcttcaaggc 3840 ttttcttttc ttcctcctcc tcgttcatct tgaggtttga cgtgtctgtt tagaattttg 3900 agctgttgca gcatcttatt ttttgttttg cgaaaacgaa gcgctttact ctcttcatca 3960 gttggacgat tgtacctttg aaaaccaact acttttgcat gttttgtata gaaatcaatg 4020 atattagaat cccatccttt aatttctttc aaagtagttg agctatagtt aagtgtaaga 4080 catccaaaag tgtatatagt gataaagaaa aggtataaat gatatgataa acagtgatga 4140 taattagtag aaagacagat gaatggcaaa gtgattaaaa ctggacgaga tttaatgaga 4200 gtagagagat agaatttaga aagttggatg tgtgaatgaa gaaatgaatg agtatattag 4260 atgatgtaga aataatatgt atgagaaaag aaagaaggaa atgcaccaag ttaaaaatga 4320 agttccatct taaagtccat tatactacta atgcaatgcc aattctgatc aatgtacaaa 4380 agacctcgtt tagatggtat ttttcctaag aatcgtcttt taatacctcg atagtaatga 4440 tattttgtac gacgatccct aatccaacaa cctagttaag aatattgttt ttccaatgca 4500 tatgcaaatg gatggatctt tttcaagatt tgcgtctagt acatcctgta gtagtcattc 4560 ctcgatattc agttcataca catcttcata aggctgaaaa catggaacat ggctgcctct 4620 tatataatct ttggatgcaa cgttgtgcag tgattttttt gtgatgatca aatgattttc 4680 cgacatggat cgccgtggaa accgtgaccg ttcatcctct ccctctatga ttggtggaag 4740 gaaccaaaaa atgccgatca gagtttgatc ttcttctgat cgtagttcat tgggaagaaa 4800 atccgtctca gtcaaggggt gaagggagaa aatcttacgt acgcacaaat ggactgtatg 4860 gcgagcgatg tcgaatgatc gacggaaaat ctttatggta cattcatggc accatcttct 4920 ttgatttgca tgtcttatag cgtcaaagta gaggaataga gtgaaatgca tcaaatgtct 4980 ttcatgaatg aaattactct tttccgtttg aaggatgttt tggattgtct gagaaatgtt 5040 ttcacattgt cctttaaccg tcttttgacg atttggtaca agttttaagg tgcgaaaatc 5100 gatatcataa tcgaatgagt ggtgtggaca aaagcgatgt aagaaaggta aagaaggaaa 5160 aaaatggaat gaaacacagt acaaaaaagt taatggaatg aaatttaaaa atagttatag 5220 atagtgatga ctcagagagc ggcaatttga aaaacaacat aataaaatta cccggaatat 5280 gatttgaata cgatttcatt gaatgtatta gatttcttta aatttttatt ttcattttta 5340 tttattttat ttttatttta tttttttaaa taataatttt tataatttat atttatttgt 5400 tttctgaact tgttctttga ttattgtaat taaattttta tctgaaattt tttttttttt 5460 aatttatttt aatttaattc ttttccatta ttgtgtatcg actattttat aaaagtttct 5520 atgttctcct ttttaaccga tataaaaatt atgtattctt ttaaccatca ttatcctctt 5580 ttttcttctt tcttttattt acgatggatt ttagtcattg taatccaaaa atcattatga 5640 acgaatttac aaaagtcaat cagttttccc tcttctaatc ttctttaaat atctttttat 5700 ttttatttat ttcttgctac atctacatct attccacgac ttgtttttcc ttcgtaccat 5760 cctcaagatc tacatgcgcc aagcaaacta aacacttgat ttgcgcagcc atatatgcac 5820 gtggattgga atgctggaaa taaacaacag tcaagtttca tacaatattt tcatgagtag 5880 ctcagatcgt agtgtatttt attcccttct caagacggtt acttgcgact ggaaaccata 5940 tattttcaat cgcaaaatta atgttaacca aggaaaattt gatacttcca acaatacgct 6000 ttattctttc aatttaatat cttaaacatg ttaaaagatc aagttagtac aacatcatct 6060 tgaaacaaat ccataatgtt atgtttaaaa aaaaaaaaaa aaaacctttc aaacatatta 6120 ttatttaggt tgcaggatac attcttcaat attcgctata gatttgttta cacattaaag 6180 tatcactttt caatctatcc ttggttcttc aacgtgcgta gttcatccat caccttgata 6240 ggatcgttaa gacccagatg cttttgcagt tctggatcag ttaccctcat aaatggatta 6300 aattgtttct cctgccccat cgttatgtgg cctgcaataa attggttgtg attgcaaaga 6360 ccctccaaat gatttaatgc ctctgattga agatgttttg aggcgaattt cacattcgat 6420 tttgtatatt cgtgtccagg ctaggaaact tgttaggaaa aaaaaaataa aaaaaaataa 6480 aaaaaaataa aaatgaatcg cttacataga tgaccgtatt attgggtaaa gatgatagta 6540 ctgcgttcaa tgcaatatgc atttcagcag ccgttccttc aaaaaagcgt ccacatcctg 6600 cgttaaacaa tgtatcccca gtgaatacag catgttcatt tgagctgtgc gcataaaagc 6660 aaatgctatc acgtgtatgg caaggcgtat ggagagcttc aatctgaacg tttccaattc 6720 gcaatgtttc tttatcctgc aacacatgag aaacaccatt ttgatcagag cctccataaa 6780 ttgtaacatg agggaattct tttttaagat tcaaattccc tccagaatgg tctgcatggt 6840 gatgagttgt gaggatggct tgcaaatcaa tctccttgtt cttcaacttt ttcttcaaaa 6900 ttggcattac cctggagctt tgtcagcata gaattgaata aaaaagatca attccaagct 6960 ttggattatt cagtcaaact taaacacttt ctctgggagc catgcctgtc atgtcttctt 7020 ggctatataa caccagtgtc aagtgataaa aattcttccg tttctcatga atagctttcg 7080 ataattaata cttacacatt tacttcggct ggatcaacaa tcgctgcttg tcgagtttcc 7140 tcgcacaaca aaagatatgc ataattatct tgagttccta cccacattgg gataggtaat 7200 atttgaaaag acatattcgt tattattatt ttaatttttc ctccttttag cccaccaaca 7260 gccttcctaa cgttcgaact tttatatata aacgtgttga agtttcaaca ttccatcggt 7320 gatcattgac cgctctatta tatgaggctt gataggcaat aaattaccta tcattttcaa 7380 gataataatc agttatcgat atcaaagcga tgcgacacac agtcctttcg ctgtagagtt 7440 ccattagttc aatatttccc aattctccag ttggtcaaaa tgcgaacgca aagagtcagc 7500 ctcgttccac cgctacatta aacaaactga tgattctatg attccatata atacgataat 7560 accattctta gcactgctct tttacaattt ctcattttat aacaaaagtc attccatact 7620 tagtacaaac aacgtaaaac tgtttgtaac tcataacccc tttttaagaa cttaatgata 7680 tttacggtta atcaactttc tgttcgtttt cattcttaaa catttcatgc gatggcaaaa 7740 tgggtgtctt tgattttgct aacaaaagat atactcatta attttacctg ttcgtcctct 7800 taaaactaaa aagtcacgcg catttaatca atggcacttt ctaattacta aatggaggat 7860 acctttaaca ttgttacatg gcattagcat tttcacttct cctaacatat atttcataac 7920 tttgctttcc ttcatatatc actttcgatt cacagaaaga aaaaccttta tgagatttta 7980 gtcaaatgat actcgcttaa aacgtctttc atacattgat cctgtacccc gtgagttttg 8040 cacaattatc tctaaatcca tcctacaact acaaattgta atgaagggct ccaaagtgat 8100 attgcctgac atgtcgaaac gccatttatt atagattcaa gaagttttta tcatgttcta 8160 agatggatgc atatgcttgt tcaacctcaa tgatagaaat ttctctttgt aggcacggct 8220 atgaacaaat acaatattta taaatttatt tcttcaaagg catgctcgtc ttaagaattt 8280 ggaacattgc tgctattcac acgttaaaga tgcattactc gaattccata cagaattgag 8340 acattaatag acttctttgg tatcactagt ttatcgattc tcaatgacaa cttggaaatt 8400 cttgtaatga ctaattcaat ttcgtatggc tgactgcctt ctccattagc tctctaggtg 8460 attagcaata gcatgaacgg gaaagaggtt aaagttttag atggctggta agcaaatgaa 8520 agaacctaga tgctatttat tgactttttg actctttatt aaattcttca aggaatcgat 8580 aaaactgttt taatgcaatt gccgttatgc atgtcagtga atgcttcatt gatttctttg 8640 agaggtcgac gatgtgtgat atatttatca atttccaatt tgtgatctag gtactctttc 8700 accaaatcgg gaagctgact tcgtcctttc acacctccaa atgcacatcc tctccatact 8760 cgaccagtaa caagttggaa cggcctggtg gaaatttctt gtccggcagc tgctacaccg 8820 ataacaatgg attgtcccca acctttatgg catgcttcta aagcggatcg cattacgtgc 8880 acattacctg tacaatcaaa ggtccagtct aatccaccat ctgtttcatg tattagtaca 8940 tcttgaattg gactttggag atcattaggg ttaatgaaat cagtggctcc aaaactcatc 9000 gcccaatttt ttttttcggg attaacatct atgccaaaaa tccggcccgc acgtttttta 9060 actgctcctt gtataacagc tagcccaaca cttcccaaac caaaaacagc tactgagtca 9120 ccctccttaa tatcagcagt gatcgtcgcg gctccatagc cagtggtgat accacaaccg 9180 agaagacaga cgctatctaa gggtgccaat cgttcaattg ctaccactga tatgtctgct 9240 acaacggtat attcactaaa tgtcgagcat cccatgaaat gcaacaaggt atttccatta 9300 caggagaagc ggctggttcc gtccggcatt aaaccttttc cttgagtagt gcgaatgcgt 9360 ccacaaaggt tcgtcttgcc ggacttgcaa aatttacacg tcttacattc tggtgtatac 9420 aaggcgatca ctggatctcc tacttggact gtcgtaactt gaggaccaac ggattcaaca 9480 atgccagcac cttcatgacc aagaattact gggaaaagac cttcaggatc ttttccagag 9540 agtgtgtagg catcagtgtg acagactcct gaatttacga ttttgattct tacttcgtgc 9600 actcgtgggg gaaatacctg aacattttca atcgacagtg gagctgctgg ttgccatgct 9660 acagcagctt tacagttaat gatctgtttt aataagcaag actctgtttt tatttaactt 9720 accttgcctg cggtgggtga ctgttgcatt tctacgctct tgaacaattt ctaaaattgg 9780 ttttaagcct ttattaagca ttggctttgg agtatttata cgctgaaaac ggctattaaa 9840 gaccgatgaa tttgcatttt aatctatcag actggcttgt gaaaatgttc gtttcagcgg 9900 caaggagatt gatcgccgca tcggaatact gaagttattt cttcatgtat ctgattacaa 9960 cttaatctat gataatagtt gtaattgaat ttattgtcc 9999 //