ID SPCC1281 standard; DNA; FUN; 23700 BP. XX AC AL035218; XX SV AL035218.1 XX DT 15-JAN-1999 (Rel. 58, Created) DT 19-JUN-2002 (Rel. 72, Last updated, Version 3) XX DE S.pombe chromosome III cosmid c1281. XX KW acyl-coa desaturase; ags1; cell wall alpha-glucan synthase; KW conserved hypothetical protein; nuclear; protein localisation; KW pyridoxal reductase; wtf pseudogene; wtf11. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-23700 RA Volckaert G., Wood V., Rajandream M.A., Barrell B.G.; RT ; RL Submitted (15-JAN-1999) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and Katholieke Universiteit Leuven, Laboratory of RL Gene Technology, Kardinaal Mercierlaan 92, B-3001 Leuven, Belgium XX DR GOA; O94519; O94519. DR GOA; O94522; O94522. DR GOA; O94523; O94523. DR GOA; O94524; O94524. DR GOA; Q8NIP9; Q8NIP9. DR GOA; Q96WS1; Q96WS1. DR GOA; Q9USK8; Q9USK8. DR SPTREMBL; O94519; O94519. DR SPTREMBL; O94520; O94520. DR SPTREMBL; O94521; O94521. DR SPTREMBL; O94522; O94522. DR SPTREMBL; O94523; O94523. DR SPTREMBL; O94524; O94524. DR SPTREMBL; Q8NIP9; Q8NIP9. DR SWISS-PROT; Q96WS1; ME24_SCHPO. DR SWISS-PROT; Q9USK8; MOK1_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c1281 is overlapped at the 5' end by cosmid c622, EMBL CC entry SPCC622, accession number AL033127. XX FH Key Location/Qualifiers FH FT source 1..23700 FT /chromosome="III" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c1281" FT /map="IIIR" FT misc_feature 1..223 FT /note="nominal overlap with cosmid SPCC17A7, EM:AL049472 S. FT pombe chromosome 3" FT CDS <1..3060 FT /codon_start=1 FT /db_xref="GOA:Q9USK8" FT /db_xref="SWISS-PROT:Q9USK8" FT /note="SPCC1281.01, len:<1019" FT /gene="ags1" FT /gene="SPCC1281.01" FT /gene="mok1" FT /gene="SPCC338.01c" FT /gene="SPCC17A7.01" FT /protein_id="CAA22822.1" FT /translation="DPTDTDEIVDDKAVAITDIDPDMEKSKVEHKRLAQEWAGLEVNEK FT YDLLVFVGRWSSQKGIDLIADIAPSLLESYKVQLICVGPIIDLYGKFAAEKLDVLQKKY FT PTRVFSQPKFTQLPPYIFSGADFALIPSRDEPFGLVAVEFGRKGALGIGARVGGLGQMP FT GWWYSVESSATPHLLKQFEQACQQALSSSQRTRARLRARSAKQRFPVSQWKAKLEALTD FT GCIKCSQKYGRNSRSRSSFYSLIHESFSRSSEVLPTSSDTNLDAKRAEEAEMIMIETPP FT TAEANTGAKLDRSLSLGSRRGPGHTTEDDASDGLDTIQEESMTAGDSTSGGSDISRYRA FT ERLNPDSHSPSEYSFDSGDYEFDPQRSYYYDDLFDDDTTIRNAPSFRPQMGSFDAEHAV FT GATFSQDDLSDPARSVDSDSVSPPLPPFVAGSNPNARNNNNPYFYGNLHTESSLSLASV FT MSGKEKRDFSLTRVEETFTDEDGQALRSFSEKLQKLNAKNSKDDLCIEQYLMKSERSFF FT HERRAIKLGLQKPNKLHVNELSSHSGTEESESLSNGQTSYDDIIAMTDESNYTQLGDDD FT FKTIHGLKKFMLFKIYDWPIYSIFLALGQILAATAYQLTLFTGTSNIQTYEIYSVCAFF FT IGASFVWWFMFARLPSYYVLSIPWLFYAVALFLVGLPAFDTVAPGRVWITNVAAWIYAI FT ASASGSIFFSLNFGEEGAVQTRIWVFRACLVQGVQQVWSAALWYWGAHLNKRLTAGEAN FT TFKMSPAIPSITWPLSAVSILIFALLFKGLPEYYRQLSGSIPAFYKSLLRRKLVVWFCI FT SVFLQNFWLSSLNGRSWSYLWDIGNIHQWQIFLLIVAFYIVLWALLLGVLAWISRTHSW FT IICVFGVGLGAPRWLQQFWATSNIGLYLPWAGYSGPYLGRTLWLWLGVLDAIQSVGIGM FT ILLQTLTRRHVASTLMTGQIVGAVATMIGRGASPNREGPANVFIDFTKWNHGDGSSILA FT SAPFWINIICQLAICVGYLAFFRRENLSRP" FT CDS complement(4146..5081) FT /db_xref="GOA:O94519" FT /db_xref="SPTREMBL:O94519" FT /note="SPCC1281.02c, len:311, SIMILARITY:Homo sapiens, O759 FT 40, 30kDa splicing factor., (238 aa), fasta scores: opt: 14 FT 8, E():0.23, (31.3% identity in 150 aa)" FT /gene="SPCC1281.02c" FT /gene="spf30" FT /product="putative spliceosome associated protein; by low FT similarity; possibly involved in pre-mRNA splicing; no FT apparent S. cerevisiae ortholog" FT /protein_id="CAA22823.1" FT /translation="MEKELEEYKSQLALVQISLQKTPQNEELQLLENDLKELISLTENL FT LQESVENDKNTFQNSQNGVAGFNTSKPVHIDFTPGNLVMARWVSGDYLFYPSRITAVSG FT FGANKKYTVQFLDYPDIETVSLKHIKAMPEEKRQEIEGNKEILKKSTTIRSTPVREPTK FT AISVASMSTSPSNYASRASSPDMKSSAAVTANVSPIQNVAQHVSTLPKISPIPPSNPPP FT VPSVSYSQKQQKQLKPKAALEASQNSWKQFAARGVKTGRVGKRKKIGESSIFKSTEDFP FT GRTNPKNFGNVARSGHREKHIYNYREDEDS" FT CDS complement(5688..6269) FT /db_xref="SPTREMBL:O94520" FT /note="SPCC1281.03c, len:193, SIMILARITY:Saccharomyces cere FT visiae, YGY1_YEAST, hypothetical 21.5 kD protein in sec15-s FT ap4 intergenic region., (190 aa), fasta scores: opt: 405, E FT ():3.1e-20, (41.1% identity in 180 aa)" FT /gene="SPCC1281.03c" FT /product="hypothetical protein; similar to S. cerevisiae FT YGL231C" FT /protein_id="CAA22824.1" FT /translation="MHINEETDWIDLVKPALAKKPKKIVDNSDKFPTPRGFQQKSLVSK FT NIHSGNSASSTSIFAKREEELQKDLLLKKAWELAYSPLKQIPMNAILAYMSGNSLQIFS FT IMTTLMLLVNPLKAITSTGSAFTPFKGTHPGTLWPAMGAYILFQLLLMGIGVYKLQRMG FT LLPTTTSDWLAWEVSKVFMDRSYGPSKTVL" FT CDS 8458..9459 FT /db_xref="SPTREMBL:O94521" FT /note="SPCC1281.04, len:333, SIMILARITY:Schizosaccharomyces FT pombe, O14295, hypothetical 36.8 kD protein c9e9.11 in chr FT omosome i., (333 aa), fasta scores: opt: 1713, E():0, (74.5 FT % identity in 333 aa)" FT /gene="SPCC1281.04" FT /product="pyridoxal reductase homolog" FT /protein_id="CAA22825.1" FT /translation="MPIVNGFKVGPIGLGLMGLTWRPKQTPIKQAFELMNYALSQGSNY FT WNAGEFYGINPPTANLDLLADYFEKYPKNADKVFLSVKGGTDFKTLAPHGDPESVTKSV FT KNALTRLRGKKKLDLFQCARVDHKVPIETTMKALKAFVDSGEISCVGLSEASAESIKRA FT LAIVPIAAVETEYSLFSRDIEKNGILDTCTQLSIPIIAYAPFCHGLLTGRVKTAEDLKD FT FIKAFPFLRNMDKFNPKVFEKNIPFLKAVEQLAQKFGMSMPEFALNFIIANGKGMIIPI FT PGSTTVQRAESNLSALKKSLSSEQLEEAKKVLDKHQIFGLRYNKQLESTLSI" FT CDS 10454..11626 FT /db_xref="GOA:O94522" FT /db_xref="SPTREMBL:O94522" FT /note="SPCC1281.05, len:390, SIMILARITY:Saccharomyces FT cerevisiae, NPL6_YEAST, npl6 protein., (435 aa), fasta FT scores: opt: 607, E():2e-31, (33.7% identity in 359 aa)" FT /gene="SPCC1281.05" FT /product="possibly involved in nuclear protein FT localisation; similar to S. cerevisiae NPL6" FT /protein_id="CAA22826.1" FT /translation="MDSTAGSDASTPTNHTVSSKKRRGRPPKGSYAAYGSSDDDDEEYS FT GRTRRRNRNTRPRVSAPSSSSTVVPKDLYSHRATLEDDELNFGVVDPEGEKKVNELGYL FT NGGREYRCRTFTCLGRGNRLYMLSTEPARAMGYRDSYLLFLKHRSLHKIIVDDSEKWDL FT IERNIIPHSYKGRAVGIVAARSIFREFGARIIVGGRRIVDDYWEGEFRARGFVEGELAD FT PDDKLPPPGMPYNRNQYVAWHGASAVYHPQPSLEAQLPAAARKRKKEPPKDATWLFQHA FT KATAAYNNDITKYLVQKQDIGYFEPHTNLLHVPLNTQPTKTHWIQAKTGTECPAPKLDI FT LVALNSDVAPQVSIANIPPSVYASCPLHVQEAIRKRQEQEIRSIRLNSMY" FT CDS complement(14346..15785) FT /db_xref="GOA:O94523" FT /db_xref="SPTREMBL:O94523" FT /note="SPCC1281.06c, len:479, SIMILARITY:Ajellomyces FT capsulata, Q12618, acyl-coa desaturase 1, (476 aa), fasta FT scores: opt: 1816, E():0, (53.8% identity in 472 aa)" FT /gene="SPCC1281.06c" FT /product="putative acyl-coa desaturase 1; similar to S. FT cereivisiae OLE1" FT /protein_id="CAA22827.1" FT /translation="MTAPSATAFSSATTQPTTEGNASMRKRTIPVVPSVPERKWDPKAP FT KHIQEQPWTMQNWWRHLNWLHCMLIFGLPMIAIYGVFTTPLQTKTLIFAIIYYAYSGLG FT ITAGYHRLWSHRAYKAKKPLEYFLAAGGAAAFEGSIRWWSRDHRAHHRYTDTDKDPYNV FT KKGFWYAHVGWMIILQNPRRIGRSDVSDLNSDPFVMFNHRHFLPIASFMAFIFPSLFCG FT LLWGDYRGGYFYAGVCRLVFVHHATFCVNSLAHLIGSQPFDDTNSARNHFITALVTLGE FT GNHNYHHAFPNDYRNGLRWYEYDPTKIFIYIASLFGLAYNLNTFPDNEIQKGIVQQKQK FT VLDRWRAKLNWGIPLEQLPVMEFEDFLEQSKTRPLVLINGVVHDMTGFEHPGGQGLLRS FT AFGKDATAAFNGGVYDHTNGAHNLLSTYRVAVVRGGMEVEVWKSGAGAQLPMKDTQGQK FT IVRVGEQITRIQPPIEAAAAN" FT misc_feature complement(14865..15584) FT /note="Pfam match to entry PF01069 Desaturase, Fatty acid FT desaturase" FT misc_feature complement(15822..19244) FT /note="low complexity gene free region" FT CDS complement(19281..20222) FT /db_xref="GOA:O94524" FT /db_xref="SPTREMBL:O94524" FT /note="SPCC1281.07c, len:313, SIMILARITY:Synechocystis sp., FT P74752, hypothetical 36.5 kD protein., (319 aa), fasta sco FT res: opt: 1019, E():0, (52.3% identity in 306 aa)" FT /gene="SPCC1281.07c" FT /product="glutathione S-transferase" FT /protein_id="CAA22828.1" FT /translation="MSNTHITDWSSKDGEFRRQVSSFRERISPEHKYFQPEKDRYHLYV FT SYACPWAHRTLIVRKLKGLENVIPVHVVGWLMGPNGWNFDKENDSTGDPLYNSPYLRNL FT YFRADPNYNMRFTVPVLWDSKYNTIVNNESAEIIRMFNDAFNEVIEDEEKRVVDLYPSS FT LRTKIDELNDYFYDTVNNGVYKTGFATTAEAYEKNVRVVFQGLDRLEQVLKESKGPFLL FT GDHLTETDVRLYTTIVRFDPVYVQHFKCNIGTIRHNYPHINQWLKRLYWKHPAFHETTD FT FKHIKCHYTQSHTQINPLGITPLGPIPNVEYF" FT misc_feature complement(19416..19649) FT /note="Match to PF00043 GST, Glutathione S-transferases. FT Score 24.28" FT CDS join(21035..21191,21354..21674,21722..21952,21991..22043, FT 22100..22132) FT /db_xref="GOA:Q96WS1" FT /db_xref="SWISS-PROT:Q96WS1" FT /note="SPCC1281.08, len:264," FT /gene="SPCC1281.08" FT /gene="wtf11" FT /gene="meu24" FT /product="hypothetical wtf protein; meiotic expression FT upregulated" FT /protein_id="CAA22829.1" FT /translation="MNSNYVPLTSSVDVEEKMESENGVDLGNDIDLEKGLPLKYNSENE FT SGLPSNSASSYLINPDPTMDLEAQTFNHNESTTSVGHDNSNSPPKCRKTCSSNKVYSNE FT VPLLFVFVISISIVCIFDLVIFGCLQYNMVSMDDLHVMQRLSWFCASLALLFILMRYYD FT FWTKACKDGIKHIFKKWKNTPLAFLQVLIFNIIGFFVRKGLKDSFGEQWGLKTSLFAHV FT SFATMSIFIFIFETLKPGSCSVDWIARILKAVVYFLEDSDEL" FT misc_feature 21192..21197 FT /note="gtacgg, splice donor sequence" FT misc_feature 21340..21353 FT /note="ttaactattcgtag, splice branch and acceptor" FT misc_feature 21675..21680 FT /note="gtaagt, splice donor sequence" FT misc_feature 21710..21721 FT /note="ctaattcattag, splice branch and acceptor" FT LTR 22526..22874 FT /note="wtf" FT misc_feature 22808..23700 FT /note="nominal overlap with cosmid SPCC622, EM:AL033127 S. FT pombe chromosome 3" FT misc_feature 22875..23700 FT /note="wtf pseudogene" FT CDS join(23186..23324,23556..>23700) FT /db_xref="GOA:Q8NIP9" FT /db_xref="SPTREMBL:Q8NIP9" FT /gene="meu24" FT /gene="wtf16" FT /gene="SPCC1281.09" FT /gene="SPCC622.21" FT /product="hypothetical wtf protein" FT /protein_id="CAB63875.1" FT /translation="MKNNYTSLKSSVDEEDELKTGHEIDLEKGPLPEHNSEGESTLPPY FT SDISKLANLVPEDSSTGPTETANPNVERRQEFKDLHPNIYSLLRLLIAVL" XX SQ Sequence 23700 BP; 7500 A; 4212 C; 4601 G; 7387 T; 0 other; gatcccacgg ataccgacga gattgtagat gacaaggcag tggctattac agatattgat 60 cctgatatgg aaaagagcaa ggttgaacac aagcgattag ctcaagaatg ggctggttta 120 gaggtaaatg agaagtatga tcttttggtc tttgtcggtc gttggtcttc tcagaaaggt 180 attgatttga ttgctgatat agccccttcg ttgcttgaat catacaaggt acaacttatc 240 tgtgttggcc ctattatcga tctttacggt aagttcgctg ctgagaaact tgatgtttta 300 cagaaaaagt atcctacacg tgttttctcc caacctaaat tcactcaact tcctccctac 360 atttttagcg gcgctgactt tgctttgatt cctagtagag atgagccttt tggtttagtc 420 gctgttgaat ttggacgtaa gggagcttta ggtatcggag ccagagttgg tggtttaggt 480 caaatgcctg gttggtggta ttctgtagaa tcaagtgcta ctcctcattt gttaaaacaa 540 tttgaacaag cttgtcagca agcgttatca tcttctcaac gtacccgtgc tcgacttcgt 600 gctcgttcag ccaaacaacg ctttcccgtt tctcagtgga aggctaaact agaggcactt 660 accgatggat gtattaaatg tagccaaaag tatggaagaa attctcgctc tcgttcttcc 720 ttctactcat taatacatga atcctttagc cgttcttctg aagtcttgcc tacaagcagt 780 gatacaaacc tagatgctaa aagagcagaa gaagctgaga tgattatgat tgaaacccca 840 cctactgctg aagctaatac tggtgccaag ctggatcgtt cattatctct tggtagtcga 900 cgtggacctg gccatacaac tgaagatgat gcaagtgatg gattagatac tattcaagaa 960 gaaagcatga ccgctggaga ttctacttct ggtggttccg atatttcaag atatcgggct 1020 gagcgattga atcccgattc tcactctcca tcagaatata gttttgattc tggtgattat 1080 gaatttgatc cccagcgttc ttattattac gatgatttat ttgatgatga caccaccatt 1140 cgtaatgcac cttctttccg acctcaaatg ggaagttttg atgctgagca tgctgtgggc 1200 gctactttta gtcaggacga tctttcggac cctgctagat ctgttgattc tgattctgtt 1260 tctccaccat tacccccgtt tgttgctggc tcgaatccaa atgctcgcaa taataacaac 1320 ccttactttt acggtaactt gcatactgaa tctagtctta gtcttgcctc agttatgtca 1380 ggaaaagaaa agcgtgactt ttctttgacg agagttgaag agacttttac tgatgaggac 1440 ggtcaagcat taaggtcgtt ttctgagaag cttcaaaaac taaacgccaa aaattctaag 1500 gatgatttgt gtattgaaca atacttaatg aaatcagagc gatcattttt ccatgaacgt 1560 cgtgcaatta agttaggttt acagaagcca aataaacttc acgtcaatga gctttcatct 1620 cactcaggca ctgaagaatc cgaatccttg agcaatggac aaacttctta tgatgatata 1680 atcgccatga ctgacgagtc caactacact cagctaggag acgatgattt taaaacaatt 1740 catggtctca aaaaatttat gcttttcaag atttacgact ggccgattta ttctattttc 1800 cttgcacttg gtcagattct tgccgcaact gcatatcaac ttacattgtt taccggtact 1860 agcaatattc aaacgtacga gatctactct gtttgcgcgt tctttatcgg cgcttcattt 1920 gtatggtggt ttatgtttgc tcgtcttcct tcttattacg ttttgtcgat cccttggctt 1980 ttttatgcgg ttgctttgtt tttggtaggg cttcctgcgt ttgacacagt cgctcctgga 2040 cgtgtatgga ttacgaacgt tgccgcctgg atatacgcca ttgcttcggc tagcggatct 2100 atcttctttt ctttgaattt tggtgaagaa ggtgctgtgc aaactcgtat atgggttttc 2160 cgcgcatgct tagtccaagg agttcagcaa gtatggtcag ctgctttgtg gtattggggt 2220 gcccatctca ataaaagatt aactgctggt gaagctaata cttttaagat gtctcccgcc 2280 attccttcaa ttacttggcc actgagtgct gttagtatct taatttttgc attattgttt 2340 aagggtctac cggaatatta tcgacaattg tctggtagta taccagcctt ttataagtca 2400 cttttgcgaa gaaaactggt ggtttggttt tgcatttccg tctttttgca aaacttctgg 2460 ctatcatctc ttaatgggcg ctcctggtct tacttgtggg atattggaaa tattcatcag 2520 tggcaaattt tccttttaat tgtagctttc tatatcgtcc tttgggcctt actacttgga 2580 gtcctggctt ggatatctcg aactcactcc tggattatct gcgtttttgg tgtcggattg 2640 ggtgctccta gatggttgca acaattttgg gctacttcaa atattggctt gtacctaccg 2700 tgggcaggtt attccggtcc ttatcttggt cgtacactat ggctatggtt gggggtgtta 2760 gatgctattc aaagtgttgg aatcggtatg atattgctgc aaacattaac tcgtcgtcac 2820 gtagcaagta cgcttatgac tggacagata gttggtgccg ttgctacaat gatcggacgt 2880 ggtgcatcac ccaaccgtga gggacctgct aatgtattta ttgactttac taaatggaat 2940 catggtgatg gctcttcaat cttagcaagc gcaccttttt ggattaatat tatttgtcaa 3000 cttgctattt gcgtaggtta tttggccttc ttccgtcgtg aaaaccttag tcgtccttag 3060 ttttctagtc ttagtcttac aaagcgaaat tttaattgaa gttcacgaaa tcggagcatg 3120 tacagttact gtgatgtttt aaacaaaata tcctccaagc tcggtcttgt tgagcatcag 3180 gtcttttaaa tgaatacttc aagttatgtt tcattatatt ctatatccac cttatttaac 3240 ttcctcatat ccttgttact attcttatct agtttccgtt ggcatttggc tttgctgacg 3300 agaatgtgtt atatctaagc tttatttaag ggaatatcac ttggtcatac ataaattgca 3360 ttataaattt caattagcat agtatctaca ttttatgata agtgttacat gtttccatta 3420 aaacaaaatt aaatctatcc gccctttgta tgcttaccga tttctttcat acaattagat 3480 tttttgtaat actagtatat tagaggagct agttttcatt gctgtctgtg gatgatccct 3540 caacatatac ggctttatat acctcttata gaatacgaat gacaaataga atatttcagt 3600 ttatcatgta acaatgctat taaaaacata agttgccgtt atttaaaaga gcatggcgag 3660 acaagatagt accaccaccg atttactttc accaactatt gtaaactaag aagtcaaatt 3720 ttggtggaat acaattagca aatgtcacgg gaaatggatc tattgtttaa gaacgaaatg 3780 actatttcgc atcagaaaat agtaatgatg ctattcataa aaccgtatgc agatgtgaat 3840 ataaaaaagt agtctatggc tgttaaattc ttaagatgcg aaaggtaata attcttttct 3900 aattactcat tcctctctaa tgtatacacc aacaacaaca aaagaattgt tttatagctg 3960 tagacaatgc gacgaacaat ttgttaaata tggaaaacca ggacagcttc atcagaaatt 4020 aggttaaaga tctgtaaaaa gcttatttat gcttattgca ccaaaaaata tataaatgaa 4080 aacataaaca gcggctgtta aaagcctatt aattaaatac caagtttcaa atgaagacac 4140 attgctcagc tatcttcgtc ttctctataa ttatagatgt gcttttcgcg atgcccagac 4200 ctcgcaacat ttccaaaatt tttagggttt gtccttccag gaaaatcttc agtgctttta 4260 aatatactag attctccaat cttctttcgt ttgccaacgc gtccagtttt tacacctcga 4320 gcagcaaact gtttccaaga attttgtgat gcttcaagtg ctgctttagg ttttagttgt 4380 ttttgctgct tttgggagta tgaaacacta ggaacaggtg gagggttaga gggaggaatg 4440 ggagagatct ttggtagggt tgaaacatgc tgagcgacat tttggatcgg agatacgtta 4500 gccgttacag ccgccgaact cttcatatct ggagaagagg cacgagacgc ataattggaa 4560 ggacttgtag acatagatgc tacagatatt gcttttgtag gctctctaac aggtgtacta 4620 cgtatagtgg tagatttttt gagaatttct ttatttcctt ctatttcctg acgtttttcc 4680 tcaggcatgg ccttaatatg tttgagggaa acagtttcaa tgtcaggata gtcaagaaat 4740 tgtactgtgt actttttgtt tgcaccgaag cctgaaacag cagtaatacg tgaaggataa 4800 aataaataat ctcctgaaac ccatcgggcc attactaaat ttccaggcgt aaagtcgata 4860 tgtactggct ttgaagtatt gaaacctgca acaccatttt gggaattttg aaacgtattt 4920 ttatcatttt ctacactttc ttgtagtaag ttttcagtaa ggctaattaa ttcctttaaa 4980 tcattttcca gtaactgtaa ttcctcgttt tggggagtct tctgaagaga aatttgaacg 5040 agagcaagct ggctcttgta ttcctctaat tccttctcca tacgattact tttatagatt 5100 taatagattt ttttttcaaa cagtaaaaat ttccaagtgt aatggcttta tcgccaaaac 5160 cggttgtaag tgtagataat atgtgaagca ggcgctcagt gaagtgcctg aaaattaagc 5220 tcagctatta cactagggtg aagaaaacaa tattggagtg agattaaatt tatactaaaa 5280 gcactaattc tttaactcaa tatactaaga cattattgat aatagttaaa acaaagaaga 5340 atatttgata tttctatatt cagtataatc aagacgtaaa agaaagtatt ctatcaaaaa 5400 tttcatgctc tcgaaaacta tggatgggta aaaagaactg gataatcaag tattttcgag 5460 gttcgtttat ggcgtgcatg atatcgatta aaggcattga acgtttaatg ccgcataatg 5520 gaggataaat tattaatcca gaagacaata tgtttccgaa ctccaagcat tccttcttta 5580 tatgaattta ttattttcta ggtcagctag aagcaatggc attaggaggt actataattt 5640 aacgatttca ctcgtatatc tttaaaattt tggagtaaat gaaattctta caaaacagtt 5700 ttactaggac cataagatcg atccataaag accttcgaga cttcccaggc aagccaatcg 5760 ctggtagtcg ttggcaataa tcccattctt tgcagcttat agactccaat ccccataagc 5820 aataattgga ataaaatata agcacccata gcgggccaaa gggttcctgg gtgggtgcct 5880 ttaaatgggg tgaaggcaga tcctgtagat gttattgctt tcagtggatt tacaagcaac 5940 ataagagtcg tcataatact gaaaatttgt agtgaattac cagacatgta tgctaaaata 6000 gcgttcatag gaatttgttt aaggggggaa tatgcaagct cccatgcttt ctttagtaag 6060 agatcctttt gtaattcttc ctctcgttta gcaaatatgg aagttgagga agctgaattt 6120 cctgaatgaa tgtttttgga aaccaacgac ttctgttgaa atcctcgagg cgtagggaac 6180 ttgtcagaat tgtcaacgat ctttttgggc ttctttgcta acgctggttt gaccaaatcg 6240 atccaatctg tttcttcgtt aatgtgcatc ttgaaaggga aaaaagagaa atttaaagtt 6300 gcgactaaat ttttggactc gtaaaccaag gaataaattt agtcaatgaa tgaaaagcct 6360 gattgcagct aacctacagt caaaaagtat tggtagcacc tcaattatgt ttctaaaata 6420 cgaagaccag ccttatttga tgtttctgaa acaagatatt tcaccagaag tcaatctcag 6480 tttttcgtta tttgatgtaa gttgggtggt agaacaatct tttcaagcaa attaataact 6540 ttggttgaag ttaaaaattt tctggtctaa ataatttgag aacacgcctc aaaatataat 6600 atttcaaaat aaacaatata gtggaggtgg cagatgctaa ggaacgaaac tggtggtaat 6660 agtgaaaagc ccatcagcta atgaatccca aaaatacaag cgcaaacaat ggcaaaaaga 6720 aagccatcct gttataaaag ttcaagatta acttgctttt gtgctttctt tggttttcta 6780 ctgtctcatg gcccggatat gaatatgtac aacgcttaaa catctaatgt taatgatttc 6840 ttgttaatta tcaaacccaa cgatcattat tgattacagc tggaattagt tttggtttct 6900 tttatggata taggatcttg atcttgaaaa agttctgact ctttatctta caatggtaat 6960 accatgctca atgattgata tttttacact gagatgtttt caaatattca atggataaag 7020 aacatatcgt tttgtaactt tttaagcata atctcgttag ccaagctatt acataaacaa 7080 agatcggata cagtatgaaa gtactcatgg tgtaaatatt taggaagacg tgttttggag 7140 ggcactcttt gtgagaattt ttttcttatt ctagaatatg agttttaaca tattgccgca 7200 agcccaaaat tgagttgtac gactcaatat actctgccta aaaagtaagt gcattttcga 7260 agcataaaga aaaaaaatga acattactgg aaatttattt tgaaataatc gctttttaat 7320 cgtgtaatgt attgttattg attaccttac cgatactgat aatgcttgct tttctcctgt 7380 ttcgagtttc cgttcaaaag acttcttgtt tatgatatat gactgcgcat aagaagtgat 7440 aattgtcctt gtatattaat attgcctgaa ataacttgta agaccgagcg tctaattttt 7500 aaaaatatat aatatcaaga ggaaaaactt gccgttctgc tatgatagag caaagtcgaa 7560 aacaacgtga accttcaacg aaattcttta caatttataa accatttcaa gtcctccatt 7620 ctttaaaacg gaatgattct ccttgcactc gaatctcaca taaatatatt caacgaaata 7680 taaaagacac tttgtttatt ttcaaatagc ttgtttgcta gaattgctgc tacgactaat 7740 tcaaaggcag cctttggaaa ttgaacaaca ttaaatacga ctctagtttc cattgtttca 7800 ttactgctct tttataccgt tcacagtttt ctaagacccc tcaaataaaa gcaattcgcg 7860 cttttgtaac taacttcatt ctggcctaat tcatacgaaa cactaatgaa tgggataagg 7920 accgttgggc agttttctga gtaaagtaat aataacagta tcctgttgca tttgatcaaa 7980 ttataaaatg atctaaaaaa ctcaagcacc catgatatga accgtaaaaa acctttcctt 8040 tttcagagac ctgggtacag aaacttgatc acggtttatt atagataagg gccactgtaa 8100 aaacataatt caaaaaaata taaatcaatg ttatctaaaa aagcagagaa ataagaaatt 8160 tcactaatca acagtaaacg tgtgggaaag gttgaatgtt gtaagactag cgtcacatcc 8220 ctccaaatta taaatcagaa caaaatttat actgacgctc acgaaataca aattactgaa 8280 gattcataaa cagacgatat tttccttgat ttttgtttca agttggtttt ccccattttg 8340 aaactatttg gtataccaat tgcaccagaa ctgaaagtat agtagacatt tacttttcgt 8400 gagaattaga gaatttctta aaattatttt tcttctcgat ttgactgtca tttcacaatg 8460 cctattgtga acggttttaa agtaggacct attggcttag gccttatggg tttaacttgg 8520 agacccaagc aaactcccat taaacaagcc tttgagttaa tgaattacgc cttgtcccaa 8580 ggttcgaact attggaatgc tggagaattc tatggcatca atcctcctac tgccaattta 8640 gatttgttgg ctgattattt tgaaaagtat ccaaaaaatg ccgataaagt atttttatca 8700 gttaagggag gaacagattt taaaacactc gctccccatg gagatcctga atcagtgact 8760 aagagtgtaa aaaatgcact tactcgttta cgtggaaaga aaaagctaga tctcttccaa 8820 tgtgcccgag ttgatcacaa agttccaatt gaaactacca tgaaagcatt gaaggctttt 8880 gtagactcag gagaaatttc atgtgtcggt cttagcgagg cttctgctga aagcatcaaa 8940 cgcgcccttg ccatcgtgcc tattgcggca gtcgaaaccg aatactctct attctcacga 9000 gatatcgaga aaaatggcat tctcgatact tgtacacagc tctctatccc aataatcgct 9060 tacgcgcctt tctgtcatgg acttttaact gggcgtgtca agactgctga agatcttaaa 9120 gactttatca aagcatttcc cttcttacgg aatatggaca agtttaatcc aaaagttttt 9180 gaaaaaaata tcccgtttct taaagcagtc gagcaattgg ctcaaaagtt tggtatgagt 9240 atgcctgaat tcgctcttaa cttcattatt gcaaacggaa aaggcatgat cattcctatt 9300 cctggatcta caactgttca acgagctgag agcaatctta gtgcactcaa gaaatctttg 9360 agttcagaac aacttgaaga ggctaaaaaa gttttggata aacatcaaat ctttggactt 9420 cgttacaaca aacaacttga atccaccctt tccatctgag catgatttta gcaacttcac 9480 cgatttgagt tttttattta atatttgcat ttaaccttaa ctcctctcta gatttagatg 9540 tatacatgct gtgtcatcct atcggcatca atacaataaa atatttcttt aaaaactaag 9600 actgtagtct ttgagtttat tcacaccttt atatattatt ctctattgtc agtgatttat 9660 cttacactgt gtaaaaaata gaaagtaagg tagtgtaagg aacaagaaaa ctttcaataa 9720 gctttgggta taattgaata atcagaaact tcctttacac agaataatca tgactttggt 9780 gacacaattt tttagaatgt caactgctct gcataaagta atttaggaac gaaattgtag 9840 ccttgatata aattcaaccc taaagtatta tgatggtcta cggttatttc ggtctagtcg 9900 acgatgcaca aaatgagatg tcaataagcg cgatgcttca atcattttct tgaaacttat 9960 tttaatcaat aggaattatc tacagatagg ttacgctcga ttattaattg cgataagaat 10020 ttacattgaa ttggttgcca aggctggaga ttcatttttg aattcaatac aacaatgaaa 10080 acccaacgta ttatggtgct tcaaaaagcg gtgtagtaga aagtatttta tttaactgct 10140 agtatcttct acgactgaca atcgttactc atttcttagg tgttttcaat cctgcatcta 10200 ggaagacgat catcattctt actcttattg tttccgccaa tatgcttttg atatttagtt 10260 atctaaatag taggctgctt gtatcagtat aacatgtagc accaaggtat gcgttactaa 10320 cagtaggatg ggtttagtgg tagttgtgct aactataacc aaactcacca ccaaaaaaag 10380 caatttttaa cacagtgcta ttcagtacga taagattgaa ctgtttatgg aataaacacc 10440 ttgcaattaa agtatggatt ctacggctgg ctccgatgct tccactccta caaatcacac 10500 ggtaagctcg aagaagcgaa gaggacgccc tcctaagggt agttacgccg catatggaag 10560 tagtgatgat gatgatgaag aatactctgg gcgtacgcgt cgtagaaatc gtaatactcg 10620 ccctagagtt tcagcgccgt cttctagctc aacagtagta ccgaaggatt tgtactcaca 10680 tcgggctact ttggaagatg atgagctaaa ctttggtgta gtagatccag aaggagagaa 10740 aaaagtgaat gaattggggt atttgaatgg cggtcgagag tatagatgtc gaacgttcac 10800 gtgcttaggt cgtggtaatc gattgtatat gctttccacc gaaccagcga gagcaatggg 10860 ctatagagat tcgtatttat tatttttgaa gcatcgttca ctgcataaaa ttattgttga 10920 tgattctgag aaatgggacc ttattgaacg aaatattatt cctcattctt acaaaggccg 10980 tgcggtaggt attgttgctg ctcgttctat ctttcgtgaa tttggtgcta gaatcatcgt 11040 tggtggtcga cgaattgtag acgattactg ggaaggagaa ttccgcgctc gtggtttcgt 11100 cgaaggagaa ttagctgatc cagacgataa attgcctcct cccggtatgc catacaatcg 11160 aaatcaatac gtcgcttggc atggagctag tgcagtatat cacccgcagc cttcactaga 11220 agctcagctg cctgcagctg ctcgaaaaag aaaaaaggaa cctccaaaag atgccacatg 11280 gctttttcaa catgctaaag caactgcagc ttacaataat gatattacaa aataccttgt 11340 tcaaaaacag gatatcggtt attttgaacc acatactaac ttgttgcatg ttccccttaa 11400 tacccaacct acaaaaaccc attggattca ggcaaagact ggtacggaat gtcctgcacc 11460 taaattggat attctcgttg ctcttaactc ggatgtggct ccacaggtgt ctattgcaaa 11520 tatccctccc tccgtttatg cgagttgtcc actccacgtt caagaggcta ttcgcaaacg 11580 tcaagaacaa gagattcgta gtattcgttt gaatagcatg tactagagtg ctcgttttct 11640 tttaatccta ttttgttttg gatgttttat aatattaatt ttcagattgt atacagtcat 11700 ttatcacacg tacgacgtaa gcccgaatta tcttcttact cgagttattt acggagaaaa 11760 catgcgttaa cgaaatccaa aacttgttaa tcaattactt tagtactttg tttttgctta 11820 gtaaagcgga aaaaaagata ttgtctacaa aaatcagatg tacattcaac aaaactatta 11880 aagaaatgat ggcgcgacgt ttccattgaa tgaaacgttt accaaccgaa accaatcgat 11940 tagcttgtat cctctcactt gtcctaatcg gtccagccga gggcgaagaa tattatggag 12000 gattgtttga tgaattattg ggcatggtca ggtcgtaggt taaaaacttt aggtaagtca 12060 aaacgtggct ttggcgaagg agtatttgtg agaagaacga ttgctgttat aatgaatatt 12120 aaataagcaa aaccgatcac catccacatt ataaagaaaa aaccattgaa tcccttcaaa 12180 taatacacca ggtcgacaat ataagcaacc aagtggagga caaggaaaac atacccgaat 12240 tgtcgaagaa tgataaactt cttcatcgtc gcctgggtgt acattttata tgtgagctca 12300 cctcttactg ctatcctgtc gtaccctgcc atgatgatga aaccgagaga agtagatatt 12360 cgtgtaacgt gcttcaaaaa aaaagagcgt tttaagcaga cgagaacggt aaataaaaaa 12420 atggctcttc acgacaaata aaaaaaaaag aatggactaa ttttcaagtc caaggtgtgt 12480 cgcaaaatgt atctcatcaa tattaaatag tgagatcatt cgacgtaata aatcttctat 12540 ggactgaaag ctatgatttt tttggcattt tacattcatc catttccttg tgtcctaaga 12600 ttttttgttt acttagtctg ttttgattac gaagcaatga gtgcaagagg atccatttaa 12660 ctgcaagaat ttcgatcaca acttccaaac gtcgagtgca gagaatggat tgacaaacaa 12720 agttattatt ctataaaaga ccaaactgat aattttactg tttttatctc ttttcattgc 12780 ggatacaatg tgctttaccg ctttatcatt tttatagtaa ctattgaatc atcgaatctg 12840 gaaaatggta cagatttatc actcgttgct gttgccgatt tcatctttaa cactatcaat 12900 attgtatcta ttattgccat gattttttat actcttaaaa agttcgatat tgaaatcact 12960 agagaagtaa tggattattt tacaagatat tttgacggac agaaattgaa gaaaaataac 13020 gtataaattc aatcatttag tcaccttatt caatgttttt ctaagaaaca acgcttcagc 13080 atactagctt taatggaaaa attaacgaaa ttcaagtttc catagaatgg gtggtgaagt 13140 atgagaacac ataagctgtt aaacttacaa aattagcttt taggaaatta ccaaagaaaa 13200 aaaatctcag aaggaagaag ctcaatgtga attgctaatc accgcaataa aacttatttg 13260 gcattcattc cgtgacgttg atcaggttca gtcataaaga ctggagtgta tttatagagg 13320 atcattagat atattttcat catcggtctg actctttggc tcaaggcatt gcttatgagg 13380 aatttggttg actagaaaac ctaaggagct gccaataatt gatttgagga ttatgttatt 13440 aattttacat ttttgggacc ttcaaatttt taaagtgcat tcatcttgct catattttgt 13500 ataaagttaa cagtggacca aggttggagc acgccgtctg ccggaactga cataatactg 13560 aacagcataa acttcatagt tgtttgtgtc gtgtttattt ttggtactta taaactcaat 13620 attctttgca aaaaacatga gctagatgaa tattgagaga tttctgaaaa agccgtagta 13680 tgaagaatga atttttatat acaattttga gtctacaaat aaaatgtaca cgtatcccgc 13740 ctaataccat ttttgtaaag tgacttgtat agtattgttg agaacaacaa aaatggaaat 13800 gcccgctcaa tttcttttaa ctttgtgcaa aagaataaat agtgtccagt agcttacaat 13860 tgcaataaag aagaatttaa cttttataac ttgagatgaa acaaaaatag ataattaaat 13920 aagcaataat aataaaaaag aaacgagaat ctcgaatttt caaagtttta actaccatac 13980 tcatttcgtc tcgacaagct gttttgtgtt gataatttaa attgtttaat tatgagaaat 14040 taaaagtcta agcactgtaa gttgactgaa gtaaaaagag ttactttcga aaacgactct 14100 attcaaaatc cctacatcgt attcattcaa taacgactac cgctgtaaaa cccaaataat 14160 cattcattac tttaattaac aatcatcata caaaacagat tttttataaa gaattttaaa 14220 aggattaaaa atgcattata ttattgctag ttgttaaaag aattaaacag aaaaacttaa 14280 acatcccgag gaataattag agaaacaaga gaatagagaa catgaaagaa aaatacagac 14340 ctcatttagt tagcggcagc agcctcgatg ggaggctgaa tacgagtaat ttgctcacca 14400 acgcgaacaa tcttttgtcc ttgggtatcc ttcataggga gttgggcacc ggcaccagac 14460 ttccacacct caacctccat accaccgcga acaacggcga cacgataagt ggaaagcaag 14520 ttgtgggcac cattagtgtg gtcataaaca ccaccgttga aagcagcagt ggcatcctta 14580 ccgaaagcag aacgcaaaag gccttgacca cctgggtgct cgaaaccggt catgtcgtga 14640 acaacaccat tgatgagaac caagggacga gtcttgcttt gctccaaaaa gtcttcgaat 14700 tccatgacgg gaagttgttc aagaggaata ccccagttaa gcttggcacg ccagcggtcc 14760 aaaacctttt gcttttgttg aacaataccc ttttggattt cgttgtcagg gaaagtgttg 14820 aggttgtagg caagaccaaa gagactggca atgtagatga agatcttggt gggatcatat 14880 tcgtaccatc taagaccgtt acggtaatcg ttggggaaag catggtggta gttgtggttg 14940 ccctcaccaa gagtgaccaa ggcggtgatg aagtggttac gggcactgtt ggtgtcgtca 15000 aagggttggc taccgatcaa gtgagcaaga gagttaacac agaaggtagc gtggtgaaca 15060 aagaccaaac ggcagacacc ggcatagaaa taaccaccac ggtaatcacc ccacaacaaa 15120 ccgcagaaga gagaagggaa gatgaaggcc atgaagctag caatgggcaa gaagtgacgg 15180 tggttgaaca tgacaaaggg atccgagttc aaatcggaga catcggagcg accaatacga 15240 cgggggtttt gcaagatgat catccaaccg acatgagcat accagaaacc cttcttgacg 15300 ttgtagggat ccttgtcggt atcggtgtaa cggtggtgag cacgatggtc acgagaccac 15360 caacgaatgg agccctcaaa ggcagcagca ccaccggcag ccaaaaagta ttccaaaggc 15420 ttcttagcct tgtaagcacg atgagaccag agacgatggt aaccggcagt gatacccaaa 15480 ccagagtagg cgtagtatat aatggcgaaa atcaaagtct tggtttgtaa gggagtggta 15540 aagacaccat agatggcgat catgggaaga ccaaagataa gcatacaatg aagccaattc 15600 aaatgtctcc accagttttg catggtccaa ggttgttctt ggatatgctt gggggccttg 15660 ggatcccatt tgcgttcggg aacgctgggg acgacaggaa tagtacgctt gcgcatagaa 15720 gcgttaccct cagtggtggg ctgagtggta gcggaggaga aagcagttgc agaaggagca 15780 gtcatattgt gaagaaaaaa taataataaa aaaaaaggaa agtgagaaga aatatagaaa 15840 aaaaaactag ttccaaactt ggttctttat aaacaaagac ttggaaaaag gtctacaggc 15900 accacaaaac aaaaaaagaa gaattctaga aaaaggaaga attcaagaag ttaagcgatg 15960 tttccagacg tacaagtagt ataagggttt tttacgtatt ctcgcaaaaa aacctaaaac 16020 tgaatgtaga agggaaaaaa tgaagaggca gtaaagaaaa aaaaaacttt ttcgatacta 16080 gcacacgaca aaaggctaga gaggcacaaa aaaaataaaa taaacaaagt tgtataatca 16140 aagatacaac gagattctaa tttataggta gagaaaaaaa acaagcacca atcaaaagag 16200 aatcaaagga gctgtaagaa tttcgataaa aaggttcgaa tcaatcaaaa atcaaaaaaa 16260 aaaaaaggaa aaaatcaaag aattaaatgt aatgtaattt aattgtttga tttgatttta 16320 ttttgtttga tttcaatttg atataatttt ctcgttccga tttcctaatc tattccacgt 16380 aaatgggagg atatgtgggt ggaggtaaaa aaaaatggaa taccagggtt aaacaagcag 16440 gcaaaataaa cgtgctctgt acaaacaacc agactgatcc tcgatacagt tgggaatcgt 16500 ctttggctga tatggagaag agctaagatg acggacaagc aagtatgggg gatgcccatc 16560 cttatatagc gaagcgtgag acgaaatgac gttgagtcaa cttaggttag ggtttacgtg 16620 aggaggagtc tatggcgaaa aaggacggca agttgggaag caaaaccagg gtaacgtagc 16680 ggtgctaatc agcgcgccga taatagaaag agaggataaa atgcaagttt accctagggg 16740 gaaaggcgtc cgaaggctca gggggggaag ggtttggagg aaaatgcgaa gcggcaatga 16800 atttggacgg attggtttga tggggatggg cgaaagaacg gcggaaatcg atgggagata 16860 tgtggaggaa gggaagaaga gtaggcaaaa aagaaagcga gtaggcagaa aaaatggatg 16920 aaaagagaga gaagcaagaa ggttttatga ttataaatgt aaaattatat ttgaaaatgt 16980 tttaaaatgt aaaaaaggaa ttgaaaattt ggggaaacat tgaagttttg tgggtttttc 17040 gatttttttg tttttttttt tttttttttt ttttcgtttt tgaaaatttg gatggttttt 17100 gttttttttg gaggtttttt ttttgggaca ctgttttatc taaacaaagg atgagtttgg 17160 gtagcgaatt tgggcatttg tgcttcgttt cgtttcgctg tttgtagaaa agattgcggt 17220 tttgacttga tgtttatctt tgggtttttt gccaacgctc aaatcgtcaa gggaagaagg 17280 atctgataag cgggagtgga ggagtagaga aagcaatgaa aataaccaaa aaaaaaaaaa 17340 aagaaaaaaa aaagtgaaat gtaatgtaat gtaatgtaat gtaatgtaat gtaatacaaa 17400 tgacaaggaa ttagagttag aattagaatt agaatagaat aaaataaaat tagaataaca 17460 aaaaatgaaa ttagaataac aaaaaatgaa atagaaatgg aaattgaaat gatcaacatg 17520 aatactatga aacaaacctt tgctaatagt atagaaattc caacattatg gattgcacac 17580 atattggcaa tgaagtagcg caccgcaccg caccgcgctg tctagcccag tgaaaccgag 17640 aggaaagaag gaaagaaaat aaaagaaaaa gaagaaaata aaaagaaaaa aacgaaaaaa 17700 ataaaaataa aatggcaaaa agcaaaaagc aaaattagtt gaatggaaat cgcaaaatcg 17760 ccacgaaatt caaactacca cgaaatctaa aagtctacta cgtaaacgac taggacaagt 17820 gagaaagagg caagtgtcag taaaaaagca agcatagatg agccagggtg agcatttgta 17880 gagagagtta aaaatggatt ttcaatattg attacattac aacaatcaat cgatcatatc 17940 aacaatatcg acaacacaat ttaaagccaa gccagtaaat actcgacaat caagcatact 18000 aaaattaaca ttattaaaaa tcaacattac taaaattaac aacaatccat tccaaacaat 18060 caacgatatt tccatattca tttctttttc ttttctttca ttccatttct ttttcatttt 18120 cttttcactt ggtttcttca aaatcctctt ttcgtttgtt tctctctcct cttcccctgt 18180 ccacctgact ttgactctcg cctcgctttc cttaacgctt cattggacct cctccttatc 18240 ttaacgagct tttgtgtact ttggtggagt tttaagattc tgcactaaag tagccctcca 18300 ccaatccccg tccacacaga tcccaaacga ggggaacaat tgccacaccc cttcggtggt 18360 tgggaggctt gccgtgggaa cctgacagga caagttcttg tagccaatca cagactcatt 18420 gataacggcg gggcattttg tggacaaaag cacgatcagc ggatggacga gaacttcagg 18480 cttaaggaga cgtaaggaag cggtcaaaag gtgtactatt tatagaattt cccacttttt 18540 ttttctttta cgcggaaaat cttttttagg tggaaattgc aactcgttaa aacggggtag 18600 agattggatt ggattggatt gggataggga ttggattttg gtttcggttt cggtttcggt 18660 ttggggttcg gtttggggtt cggttggttt tcggtttcca tttcggtttc gttaagggat 18720 atgtcaaatc caacttgaac ttgttttgaa aacaactctc ttttactgtt tctttacaat 18780 tcctttctca atacaaatcc aatacgatac tgtcttgcac tgtttggaat agcattagca 18840 ttagctttat tttacctatt ttatttactt ttcatttcct ttgtaattgc tgtgtgttta 18900 ctttttacgt tcttttctat gtcgcatctg catttgcatt tgcattcgct ttcgcactca 18960 cactcgcact cgcaccacac tcgcatttta cattcttctc gtcaacctcc cattgtactt 19020 gtttagcgga aatatcactc ggtacttttt aagcatcttc ttctctcttt tcaaacaatt 19080 cggtcggttg aagcttaact agtttaacgt ttcgtaaacg aaaaacccgc agagacattg 19140 gtattgcaca caaaaagcac gcatccaaac aaaacaaaac aaaaattcca atccaactcg 19200 ttgaattgga attttcaacc ccataaccaa tcgttcaacc caaattccaa cttgttggaa 19260 tttcttcaaa aaaaataaac tcaaaaatat tcgacattgg gaatgggtcc aagaggagta 19320 atgcctaatg gattgatttg ggtgtgactt tgggtgtaat gacatttgat gtgtttaaaa 19380 tctgtagttt catgaaacgc cggatgcttc cagtatagtc ttttcaacca ttgattgata 19440 tgaggatagt tgtgacgaat ggtaccaatg ttgcatttaa agtgttgtac atataccggg 19500 tcaaagcgta caatcgtcgt atacaatcgc acatccgtct ctgtcaaatg atctccaaga 19560 agaaacggtc ctttgctttc cttcaaaacc tgctccagtc gatcgagccc ttgaaacaca 19620 acgcgcacgt tcttctcgta cgcctctgcc gtcgtggcaa accccgtctt gtagacgccg 19680 ttattgacgg tatcgtagaa atagtcgttc aactcgtcaa tcttcgtcct cagcgacgat 19740 ggatacaaat cgaccacccg cttctcctca tcctcaatta cctcgttaaa ggcatcatta 19800 aacatacgga tgatttctgc actctcgttg ttcactatcg tgttgtactt ggaatcccac 19860 agcaccggca ctgtaaaccg catattgtaa ttgggatcgg cgcgaaagta tagattgcga 19920 aggtacggac tgttgtacaa gggatcccct gtactatcgt tctccttatc aaagttccac 19980 ccgttcggtc ccataagcca gcctaccaca tgcacaggga tcacattttc tagacccttg 20040 agttttcgta caatcagtgt tcgatgagcc caaggacatg cataactcac gtaaagatga 20100 taacggtcct tttctggctg gaaatacttg tgctcaggtg agattctctc tcgaaaggaa 20160 gatacttgtc ttcgaaattc gccatccttt gagctccaat cggtaatatg agtgttggac 20220 atggttctga tgaaaaaacg ttgctgtacc actcgattcg tcaaacgtga aaattttctg 20280 caaagcaaat ccatgccgaa tttatacaga ggcaaatggc aagtacatga gtaagcatgg 20340 tgtcatgggg tccatggttg ggattgtatc gttccccatc cacatggcca ttcatccatt 20400 cattattagt aagactgatt tcattgtgga agataaatta gaagaaagag tggaagttta 20460 acgaagtaaa aggtgctggg atgttgaaga attgcgatgc ataccgtgta cgttgttaaa 20520 tgaaaatggc aaagtacttt aagaaatacg ttgcaagatt ttagaatggt aatgcctcgc 20580 atcgctttag ctcgttactt gcattcacac tcgccctcta tgttggacgt tcagttgcct 20640 tacaacctta cagcaacaca aattacttta cgtagcgagc agtttacgga ttgctttagt 20700 tagcagtaaa ccccgatata gcgtttggat gatcgaccat cgatcgttac acacagcgaa 20760 ataaacaaaa aaatcattgt gacaaaatga tggtgtcagt aaagaaatgc aatgcctcat 20820 tgagtgttgt tcctttttcc tttttcatga atgccgttat ttgaaaaaac ttatttgacc 20880 gacttgcttg gtttgttaaa agtcgttgaa aactagtgga attcagttac aggttgattt 20940 ttagatttct ctattttgtt ttgtcttgat ctagcaatta aagtatattt gtgcataaat 21000 ctaattgaac ttacaagtta tcctttcctt gaaaatgaac agcaattacg ttcccttgac 21060 aagttcggta gatgtggaag agaaaatgga atcggaaaat ggagttgatt taggaaatga 21120 tattgacttg gaaaaaggtt tacctctaaa atacaattcg gagaatgaga gcggtttgcc 21180 ttcaaattca ggtacggttt attgtttatc ataaaaaaat gcaatagtaa agaaagtttt 21240 acttcttgtc taactgttag tgaacgttat gtgcaatcaa ctctagaata gcacgcacgt 21300 tcgtcttcct ttcccaatga actaattttt tcatttgtat taactattcg tagcttcttc 21360 atatttaatc aatcctgatc ctacgatgga ccttgaagcg caaacgttca atcacaatga 21420 atccacgacc tctgtaggcc atgacaatag caactctcct cctaaatgtc ggaaaacttg 21480 ttcatctaat aaggtgtata gtaatgaggt gcctctgtta tttgtttttg tgatatctat 21540 ttccatagtc tgtatatttg atcttgttat ctttggttgt ctacagtata acatggtttc 21600 tatggacgat ttacacgtaa tgcaacgttt atcgtggttc tgtgctagcc ttgctctttt 21660 gtttatttta atgcgtaagt gagacatgga attgtactat actcaataac taattcatta 21720 ggctactatg atttttggac caaggcatgc aaagatggaa tcaagcacat ttttaagaag 21780 tggaaaaaca cgcctcttgc tttccttcaa gtgcttatat tcaacatcat tggctttttc 21840 gtgcgaaaag gtctaaaaga cagttttggc gagcaatggg ggttgaaaac atctctcttt 21900 gcccatgttt cctttgctac tatgagcatc tttatcttca tttttgaaac atgttcgtta 21960 tatacctgtt attatattct aaccatgtag taaaaccagg atcatgcagt gtcgattgga 22020 tcgcaaggat attgaaagcg gtggtatgtt gcatgggaga cattttatga tgagttgttt 22080 tactaacaaa actttatagg tgtattttct tgaagattca gatgaattgt agcattctcg 22140 ttatgaataa gatcactaaa caagttgcga cctttgattt tattgcatac tttgtctgtc 22200 atacgaatgg cattgactag caaattgctt gaaagtatta acgattagtt taaactactc 22260 attatatttt tgcatacgag agctttatga tgatcaccac gtagaataac cgttttcaga 22320 aacagttagc tcaacttatg aaattataag attcattact tcacaacctc gatcaaaagt 22380 tgtttcatta atacttttgc tatgtacggt tttccctcca ttttggtttt tctgatgaac 22440 caaacatgtc gcttattgta tatgctttaa ttcaaacaaa tttaatgttt acaaaataat 22500 gaatagcata ataaaacatt gtgactgtca gcaatactac actacgctat aatacactac 22560 gttgcgtatc actatatgtc acatgttcta attatatata gtaccatgca tgatacgata 22620 ttgagattga tcttaatgat aatctattaa gatctatatt atctgaatac tataaataga 22680 gctactgctg aacctcgttc ctcagttcag ttatgagcta tattagtgat aggtaacatt 22740 ataacctaat taatacaata cctatactca gttgctactc atataacctg tgtaatgtaa 22800 tatgatagat cacaaggaaa actcaccgca gtactacgta tccttaaatc agataccaaa 22860 ttgcgtagct gacattatat tatactacaa cgttttgctt ctcaaaaacg tttaaggaaa 22920 gctaagttgg ggtgaataaa aagggcagtg acaaaataaa tgtgtcagaa gtaattcact 22980 gcctcgttct tcttttttta tgccattgtt tgaaggaatt agttggaaat ttgtttgaac 23040 gattttatta ttttgttaaa aagtctttaa agcgattgga attggactac agagcgaata 23100 ttcttgaatt cgctgtttcg tttgtcgcaa ttatagcaat taattcgcgc atgtatttta 23160 ttaaataaag aatgatctta ttattatgaa gaataattac acttccttga aaagttctgt 23220 agatgaagaa gatgaattga agacaggaca tgaaattgat ttggaaaaag gaccactccc 23280 agaacataat tcggagggtg agagtacact acctccatat tcaggtaagc gttgcaaaca 23340 ataaaaaaga aaaatcaatt aaacttacat cttgctgttg ctttaaaata acatggttgt 23400 ggtcattgtt tacagttggc atccccaaca ctagatcatc aaacatgcgc acattgtatt 23460 tactcatgtt atgaactcac gttaagttat caaaattgga atatatattt cactcattct 23520 ttaaatatta cacgccaggc taactataaa tgcagacatt tcgaaacttg ctaatcttgt 23580 acctgaggat tcaagtacag gacctacaga aactgcaaat cccaatgtcg aaagaagaca 23640 agaattcaaa gatttgcatc caaatatata ttcccttctg agactactaa tagcagttct 23700 //