ID   SPBC6B1    standard; DNA; FUN; 30830 BP.
XX
AC   AL021838;
XX
SV   AL021838.1
XX
DT   13-FEB-1998 (Rel. 54, Created)
DT   07-APR-2003 (Rel. 75, Last updated, Version 6)
XX
DE   S.pombe chromosome II cosmid c6B1.
XX
KW   autophagy; beta-transducin; helicase; LTR;
KW   phosphatidylinositol-4-phosphate 5-kinase; pre-mrna plicing factor; prp1;
KW   serine/threonine-protein kinase; ubiquitin carboxyl-terminal hydrolase;
KW   WD repeat; WD40; zer1.
XX
OS   Schizosaccharomyces pombe (fission yeast)
OC   Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes;
OC   Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
XX
RN   [1]
RP   1-30830
RA   Wood V., Rajandream M.A., Barrell B.G., Hamlin N., Churcher C.M.;
RT   ;
RL   Submitted (12-FEB-1998) to the EMBL/GenBank/DDBJ databases.
RL   European Schizosaccharomyces genome sequencing project, Sanger Centre, The
RL   Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail:
RL   barrell@sanger.ac.u.
XX
DR   GOA; O43065; O43065.
DR   GOA; O43066; O43066.
DR   GOA; O43069; O43069.
DR   GOA; O43072; O43072.
DR   GOA; Q11119; Q11119.
DR   GOA; Q11120; Q11120.
DR   GOA; Q12381; Q12381.
DR   SPTREMBL; O43065; O43065.
DR   SPTREMBL; O43066; O43066.
DR   SPTREMBL; O43067; O43067.
DR   SPTREMBL; O43068; O43068.
DR   SPTREMBL; O43069; O43069.
DR   SPTREMBL; O43071; O43071.
DR   SPTREMBL; O43072; O43072.
DR   SPTREMBL; Q11120; Q11120.
DR   SWISS-PROT; Q11119; UBPE_SCHPO.
DR   SWISS-PROT; Q12381; PR01_SCHPO.
XX
CC   Notes:
CC   Details of yeast sequencing at the Sanger Centre are available on
CC   the World Wide Web.
CC   (URL, http://www.sanger.ac.uk/Projects/S_pombe/)
CC   During 1995 to 1996 about 80% of S. pombe chromosome 1 was sequenced
CC   by the Sanger Centre.  The sequencing of the S. pombe genome is now
CC   being continued with funding from The European Commission.
CC   Fourteen European sequencing laboratories, including the Sanger Centre,
CC   are participating in the project.
CC   Protein coding regions (CDS) have been predicted with the help
CC   of computer analysis using the Genefinder program in PomBase
CC   (an ACEDB database) with additional predictions for the
CC   branch-acceptor sites supplied by the program Sp3splice.
CC   CAUTION: It is possible that for any individual CDS we may have
CC   underestimated or overestimated the number of introns/exons or
CC   we may not have chosen the correct splice donor/acceptor sites.
CC   CDS are numbered using the following system eg SPBC25H2.01c.
CC   SP (S. pombe), B (chromosome 2), c25H2 (cosmid name),
CC   .01 (first CDS), c (complementary strand).
CC   The more significant matches with motifs in the PROSITE
CC   database are also included but some of these may be fortuitous.
CC   The length in codons is given for each CDS.
CC   IMPORTANT: This sequence MAY NOT be the entire insert of
CC   the sequenced clone.  It may be shorter because we only
CC   sequence overlapping sections once, or longer, because we
CC   arrange for a small overlap between neighbouring submissions.
CC   Cosmid c6B1 is overlapped at the 3' end by cosmid c3E7.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..30830
FT                   /chromosome="II"
FT                   /db_xref="taxon:4896"
FT                   /organism="Schizosaccharomyces pombe"
FT                   /strain="972h-"
FT                   /clone="cosmid c6B1"
FT                   /map="IIR"
FT   CDS             complement(<1..1005)
FT                   /db_xref="GOA:O43065"
FT                   /db_xref="SPTREMBL:O43065"
FT                   /gene="SPBC1826.01c"
FT                   /protein_id="CAA17044.1"
FT                   /translation="MTTRLDRLVVLLDSGSTSVVRETAAKQIGDIQKVHPDELYNLLGR
FT                   VVPYLKSKNWDTRVAAAKAIGGIVENVPVWNPNRTSPVKKEETEDLPSFNGDTEEKPFI
FT                   KTEEGAPASSQSQVVVSSNLTSNSEVSKLEEERLSTRSHSQEIKPIVDFGPDEETAKEL
FT                   NTELKGKFENSLLSFESFDIANVLKAGKKLLGSASRDYDVNPANYSTHYLQQLSNLKSR
FT                   LDLAGEYLDDSIMNDLGDNVGSNSKGSPTTSIPEHKTSINNNKPEDTPTPSENVHLSAR
FT                   QRNALKRKARQMKNSQKVRVIDVAPTLVHQQNSTSSADKKTGADYNFTAQSRSD"
FT   misc_feature    1..101
FT                   /note="nominal overlap with cosmid SPBC1826, EM:AL035583 S.
FT                   pombe chromosome 2"
FT   CDS             3034..5895
FT                   /db_xref="GOA:O43066"
FT                   /db_xref="SPTREMBL:O43066"
FT                   /gene="SPBC6B1.02"
FT                   /product="Ark1/Prk1 family protein kinase; putative
FT                   serine/threonine protein kinase; similar to S. cerevisiae
FT                   ARK1 and ARK2 and ALK1; similar to S. pombe SPBC557.04 and
FT                   SPCP1E11.02; actin cortical patch component (predicted);
FT                   consensus phosphorylation target site [LI]XXQXTG
FT                   (putative)"
FT                   /protein_id="CAA17045.1"
FT                   /translation="MTEVYSKAPATVGQVKLSNNGTSNKAYSVPKSPAPVRTDLFSKIP
FT                   AGTKIQVGSHSVIIQRYLSEGGFSHVYLALLENEKPFVLKRIYVPDKTALQLVHGEIET
FT                   MKRLKGHRHIVNYIDSSALYSKSENRYEVYLLMEFCAGGGLIDFMNTRLQHRLTEGEIL
FT                   KILADVCDAVAAMHYLDPPLIHRDLKIENVLLVAPNSYKLCDFGSACEPLAPATTPDTI
FT                   MFLEQNIAAYTTPQYRAPEMIDINRRQGIDEKSDIWAIGVLAYKLCYYTTPFEQVGNSA
FT                   ILKASFSFPPFPRYSDRMKRFIATCLQEQPSHRPNIYQTLKEIMEMQGTPLKLPDVYGG
FT                   VNASTYNPPRAPLQRTPSGSLTPLSSRPAHTSLPPIPTVQTTSSNVPPVNRPSLKSKSP
FT                   SVSNILSNQLSPISSANNDVMARLQPKSPIPATKSYSATIQTPRSPSLRRADSTSHIIK
FT                   VPHLPDTSVKTAKTGASEIDVLSRYPSVEEIDKITDKIEVSKPLRNSGPLAFKPFEKIS
FT                   ANKQTDLLQNKPEALLDLENRFLPKPSPKPSEFSSSVGSKQNLSMDIPSVQNVSTKQKS
FT                   TNDTDNSKLKINKPLTGGYAPLPSRPNRMNHSVLNEKSNKEFVRGPRVLPPIEVSSSKM
FT                   AGLDIRKEPFTPAVPSAKSGLKKDQSSEVANKDVVSKNKDNIAILADREARPQLLLDDN
FT                   NDSSSSSSEHLISFNNHTGNKILSRQTTSSSIDSNNVQSNIEFLKGLNATHARSTSQVS
FT                   HTQRLQQSISTSLERVKSNTKKESNSPRQVSKLKRPIGASNKILSGKFGEAFKKFEFGG
FT                   EKMSRRRKSETKKNLVSILPDTEVDEYPKASNEWIVESEELPQVHETINQYRKSCETQR
FT                   SRKSHEGSNDLERQPSSPDTVHPGIKRSHFIRERVKQLLSDANKHHQSPSDSETDRTPD
FT                   SSSIHLPHIERLNLFHTKSESLE"
FT   misc_feature    3202..4011
FT                   /note="Pfam match to entry PF00069 pkinase, Eukaryotic prot
FT                   ein kinase domain, score 165.10, E-value 1.2e-45"
FT   misc_feature    3580..3618
FT                   /note="PS00108 Serine/Threonine protein kinases active-site
FT                   signature"
FT   CDS             join(complement(7312..7407),complement(6876..7245),
FT                   complement(6482..6834))
FT                   /db_xref="SPTREMBL:O43067"
FT                   /gene="SPBC6B1.03c"
FT                   /product="hypothetical protein; similar to S. cerevisiae
FT                   YHR097C"
FT                   /protein_id="CAA17046.1"
FT                   /translation="MGKNNPFVHSNANFPPLQTHNFEDIPEKGYTIFSSPRIDVFNEER
FT                   PHSGINLNQYQHHEDDAELQSNNPFLNKDSGVDLLKLHSRSNSRIYEAKPKRVIKPKIA
FT                   IIECNEMAENPPFWNQNKAFERKVSSKESFNMLGYDKIDKLDSSNSYLGDFGVHHDGPF
FT                   DPCSKHRNLDAATSPIAAFSSQSEANSLPAFLLPNNSKGVEKSEENEDGVTDNDSSNVN
FT                   SSTNESPNPTDINVCSNDDATDNTENNLKKKASFIYRLRKHLKRNSIETE"
FT   misc_feature    complement(6835..6849)
FT                   /note="ttaactaaactttag, splice branch and acceptor"
FT   misc_feature    complement(6870..6875)
FT                   /note="gtaaga, splice donor sequence"
FT   misc_feature    complement(6991..7011)
FT                   /note="PS00092 N-6 Adenine-specific DNA methylases signatur
FT                   e"
FT   misc_feature    complement(7241..7267)
FT                   /note="ttaaccgatatcgtgtactatagtttag, splice branch and acce
FT                   ptor"
FT   misc_feature    complement(7306..7311)
FT                   /note="gtacgt, splice donor sequence"
FT   CDS             8465..9730
FT                   /db_xref="SPTREMBL:O43068"
FT                   /gene="SPBC6B1.04"
FT                   /gene="mde4"
FT                   /product="no apparent orthologs; possibly involved in
FT                   meiosis; possibly involved in sporulation; Mei4p-dependent
FT                   expression"
FT                   /protein_id="CAA17047.1"
FT                   /translation="MSTISTSTDSKLDNLGLSVTSRRNQILFYLSKALNLAHLLRSDSL
FT                   QKSFLDALKQSATDSELLHKNLDEIKFLQNEKLNNEKLLEQEQNEANDYRLKVERLEHK
FT                   ISDYVQEINSLNSQLQIQKSNPEKHEDAVSQNRLRGSLDTVSSPSKTHKANKDEKATRL
FT                   HLIIANLKKALKEKDAEVLNLQSHVSSKESELDRFKIKLETEESNWKVRLQVLESKLAT
FT                   QDRKLRMQKKSTERKSLLVSPRVSSPKLFSPSKQAIMGTRQPNATSGSPLSVTPFLQKT
FT                   STSIGLSSSPPQSSPSAQSSQPFSRDKYPHSMTVSPSNARYLKKHLDDTIPSNVSDINH
FT                   NDHLKIPQSPSSLSPSKIPIRKKRKLKDTVSNCEFTEEDSESSFLLETIQPTKSTLRRS
FT                   ISPLKKRNDEINELKKGFTMKK"
FT   CDS             join(complement(11844..12034),complement(11697..11802),
FT                   complement(11323..11655),complement(10853..11287),
FT                   complement(10637..10792),complement(10174..10598),
FT                   complement(9829..10132))
FT                   /db_xref="GOA:O43069"
FT                   /db_xref="SPTREMBL:O43069"
FT                   /gene="SPBC6B1.05c"
FT                   /product="possibly involved in autophagy; similar to S.
FT                   cerevisiae APG7; possibly involved in vacuole targeting;
FT                   possibly involved in peroxisome degradation"
FT                   /protein_id="CAA17048.1"
FT                   /translation="MFVGKALQFQSFHSSIDATFWHQLSNYKVEKQKLDASPLTIHGKF
FT                   NTYSRGNISIVFGEAPSNSNIKDCLAEGTLLNANTPQEFTNADVKKIREEIGEVLLNSI
FT                   KNGVVSERPNELLRFLIFSYADIKAYKYHYWCLFPSFKETPHWIVKDLSPAESLIPSGP
FT                   ILSQIREFLSTADYYQRPFFLLIKSTLDEWTIAPLKELSHCVDKSLQFYLVAEDSVQLA
FT                   EYPSWPVRNILAFAFIKFKLKVINLFLYRDGINSDTLSKSILIKVEADKDMILEAPLSI
FT                   VGWERNGKGVLGPRVVNLSTVLDPFVLSESASTLNLSLMRWRLVPQLDLDRIQNSKCLL
FT                   LGAGTLGCGVARNLLSWGVRHVTFVDYSTVSYSNPVRQSLFTFEDCKRKLPKAECAAQR
FT                   LKEIYPNMFSTGYNISIPMLGHPIYEAGIEKTMHDYETLENLISTHDAIFLLTDTRESR
FT                   WLPTVISTAMDKLLINSALGFDSWLVMRHGSVLQKENRLGCYFCNDIFAPSNSLVDRTL
FT                   DQTCTVTRSGCANIATAIAVELFVSLLQHPNGHAAPVLNEDQTVLGELPHQIRGFLHNF
FT                   SLMKISGMAYPQCSACSECIINEWNREKWMFVLRAINEPDYVEELCGLREVQALGEIAG
FT                   TMEEWISDKESVIL"
FT   misc_feature    complement(10133..10149)
FT                   /note="ttaattatcaattttag, splice branch and acceptor"
FT   misc_feature    complement(10168..10173)
FT                   /note="gtacgg, splice donor sequence"
FT   misc_feature    complement(10571..11035)
FT                   /note="Pfam match to entry PF00899 ThiF_family"
FT   misc_feature    complement(10599..10610)
FT                   /note="ctaacaaagaag, splice branch and acceptor"
FT   misc_feature    complement(10631..10636)
FT                   /note="gtacaa, splice donor sequence"
FT   misc_feature    complement(10793..10804)
FT                   /note="ctaacgttctag, splice branch and acceptor"
FT   misc_feature    complement(10847..10852)
FT                   /note="gtaatg, splice donor sequence"
FT   misc_feature    complement(11288..11298)
FT                   /note="ctaacacgtag, splice branch and acceptor"
FT   misc_feature    complement(11317..11322)
FT                   /note="gtatgc, splice donor sequence"
FT   misc_feature    complement(11656..11671)
FT                   /note="ttaacattatgtatag, splice branch and acceptor"
FT   misc_feature    complement(11691..11696)
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    complement(11803..11817)
FT                   /note="ctaatctgtccctag, splice branch and acceptor"
FT   misc_feature    complement(11838..11843)
FT                   /note="gtaatg, splice donor sequence"
FT   LTR             12254..12597
FT                   /note="tf2 type LTR"
FT   CDS             join(complement(15354..15449),complement(13053..15284))
FT                   /db_xref="GOA:Q11119"
FT                   /db_xref="SWISS-PROT:Q11119"
FT                   /gene="SPBC6B1.06c"
FT                   /EC_number="3.1.2.15"
FT                   /gene="reserved_name_ubp14"
FT                   /product="ubiquitin carboxyl-terminal hydrolase; UBA
FT                   domain; zinc finger protein; zf-UBP type; similar to S.
FT                   cerevisiae UBP14"
FT                   /protein_id="CAA17049.1"
FT                   /translation="MSCPHLTETNVVIPDNSQVIYREECVRCFNSQDEEGGIDLCLTCF
FT                   QSGCGETGLKHSLVHFEQTLHPIVVTIARQPKQKINDEPPQKITKLEIREDSDEDLYDY
FT                   FYVPKCLVCNIILDIQDPLLSLSLEAMKNATKASNKSQLTAWENELTTCDHIINLPENE
FT                   TYVTNLDNATCSKCDLAENLWMCLTCGALSCGRKQYGGGGGNGHALSHYDDTGHPLAVK
FT                   LKSISPDGQADIYCYSCDEERIDPNIKTHMLNFGIDIAKLNKTEKSLAELQLEQNLNWD
FT                   FGASEEDDASKRLFGPGLTGLKNLGNSCYLASTMQSLFSIKEFAIHELNLFNTYNSVCQ
FT                   TPTTDLQCQLGKLADGLVSGKFSKPSKIGLLNNPSSSILPYQDGLRPFMFKDVVGQGHS
FT                   EFGTSQQQDAYEFLLYLLGKIRKSSIAKTDITKIFDFETEQKLSCLSCKRVRYSSFSSQ
FT                   GLTLTVPRVKIGEIEGEQIYEEVSIDQCLDATIQPDQMEYTCEACKSKLGATTTTAMKS
FT                   FPKVLILQANRFDLQGYQVKKLSIPIIVNEDGIYNFDRLMAKDHPNDEDYLPEKTETIE
FT                   WNQSAIEQLQAMGFPLVRCQRALLATGNSDTETAMNWLFEHMEDPEIDKPIEVSELLPK
FT                   ADSSVSEENVQSLCEFGFTVAQARKGLLESNNNIERAVDWILNHPDESFEEPPLEGSDS
FT                   SIKNENMGSWESTNVPVNYNLKAIISHKGSSAHAGHYVAFIRKEIDGKQQWVLFNDEKV
FT                   LQVASLEEAKTTGYVYLFERLD"
FT   misc_feature    complement(13188..13244)
FT                   /note="PS00973 Ubiquitin carboxyl-terminal hydrolases famil
FT                   y 2 signature 2"
FT   misc_feature    complement(13191..13313)
FT                   /note="Pfam match to entry PF00443 UCH-2, Ubiquitin carboxy
FT                   l-terminal hydrolases family 2"
FT   misc_feature    complement(13413..13535)
FT                   /note="Pfam match to entry PF00627 UBA, Ubiquitin-associate
FT                   d domain (UBA-domain)"
FT   misc_feature    complement(13431..13553)
FT                   /note="Pfam match to entry UCH-2 PF00443, Ubiquitin carboxy
FT                   l-terminal hydrolases family 2"
FT   misc_feature    complement(13599..13724)
FT                   /note="Pfam match to entry PF00627 UBA, Ubiquitin-associate
FT                   d domain (UBA-domain)"
FT   misc_feature    complement(14496..14549)
FT                   /note="Pfam match to entry PF00442 UCH-1, Ubiquitin carboxy
FT                   l-terminal hydrolases family 2"
FT   misc_feature    complement(15285..15298)
FT                   /note="ttaacaaacgttag, splice branch and acceptor"
FT   misc_feature    complement(15348..15353)
FT                   /note="gtatgt, splice donor sequence"
FT   CDS             17430..20150
FT                   /db_xref="GOA:Q12381"
FT                   /db_xref="SWISS-PROT:Q12381"
FT                   /gene="prp1"
FT                   /gene="zer1"
FT                   /gene="SPBC6B1.07"
FT                   /product="pre-mRNA splicing factor; TPR repeat protein;
FT                   involved in G0 transition (EMBL D83659 unpublished);
FT                   similar to S. cerevisiae PRP6"
FT                   /protein_id="CAA17050.1"
FT                   /translation="MANFYPDFLNMQPPPNYVAGLGRGATGFTTRSDLGPAQELPSQES
FT                   IKAAIEQRKSEIEEEEDIDPRYQDPDNEVALFATAPYDHEDEEADKIYQSVEEHLSKRR
FT                   KSQREKQEQLQKEKYEKENPKVSSQFADLKRGLSTLTDEDWNNIPEPGDLTRKKRTKQP
FT                   RRERFYATSDFVLASARNENQAISNFAVDTQAGTETPDMNGTKTNFVEIGAARDKVLGI
FT                   KLAQASSNLTSPSTIDPKGYLTSLNSMVPKNANDLGDIRKARKLLQSVIETNPKHASGW
FT                   VAAARLEEVANKLSQAQSLILKGCENCSRSEDVWLEAIRLHPAAEAKVIIANAVKKLPK
FT                   SVTLWLEAEKLENQAQHKKRIIKKALEFNPTSVSLWKEAVNLEEEVDNARILLARAVEL
FT                   IPMSIDLWLALARLETYENAKKVLNKARQTIRTSHEVWIAAARLEEQQGNVSRVEKIMA
FT                   RGVSELQATGGMLQRDQWLSEAEKCETEGAVITAQAIINTCLGVGLDEEDQFDTWLDDA
FT                   QSFIARKCIDCARAVFAFSLRVYPKSEKLWLRAVELEKLYGTTESVCSILEKAVESCPK
FT                   AEILWLLYAKERKNVNDIAGARNILGRAFEYNSNSEEIWLAAVRIEFVNNENERARKLL
FT                   ARARIESGTERIWTKSISLERILDEKDRALQLLENALKIYPHYDKLYMMKGQIFEDKEQ
FT                   IELARDAYLAGTKVCPYSIPLWLLLAKLEEKQSVIRARVVFDRAKVKNPKNEFLWLELI
FT                   KMELRAGNISQVRAALAKALQECPSSGLLWTEAIWLEPRAQRKTRATDALRKCEGNAHL
FT                   LCTIARMLWLEKKADKARSWFLKAVKADQDNGDVWCWFYKYSLEAGNEDQQKEVLTSFE
FT                   TADPHHGYFWPSITKDIKNSRKTPQELLHLAINVL"
FT   CDS             complement(20486..22033)
FT                   /db_xref="GOA:Q11120"
FT                   /db_xref="SPTREMBL:Q11120"
FT                   /gene="SPBC6B1.08c"
FT                   /product="histone acetyltransferase complex (predicted); 2
FT                   OG-Fe(II) oxygenase superfamily; similar to S. cerevisiae
FT                   YER049W"
FT                   /protein_id="CAA17051.1"
FT                   /translation="MGDTQQPTVLDRFAPHALDTSEAERLSREYHKNGPYNHVVIRPLI
FT                   NDTLLRNVRKELMENIHFTEKVTDIYRVWQTGDLANLDGLDKKEQNMLKYLRQVRDALY
FT                   SEEFRSHVQKITGCGPLSASKKDLSVNVYSKGCHLMNHDDVIGTRCISYILYLVEPDEG
FT                   WKPEYGGALRLFPTLQPSFPAADFCHSIPPQWNQLSFFRVKPGHSFHDVEEVYVDKPRM
FT                   AISGWFHYPQPGEPGYDANYCDNTVSTLQSLTMKQMDLELPRFSYYPVVKPEPLSKQDT
FT                   DILSNYINPLYLTPDGIEKLSKRFFQDSVIVLVEFLNQEFANTLLKRIIDAERQPTPMH
FT                   SSEVSFPWKTAIPPHKHRYLYLDHEEFGPDIILPMDLQRLPAFQRWIQLVSGLPLRSFH
FT                   QVGRRFRPGSDFTLATTNDTALLEATLCLSPGTGIANTDNGAYDIYMIGDEDPDVDAAV
FT                   YRGDQQDDSILLSLPAAWNVFSLVYRDEGVLQFVKYVSRQAESSRWDIYSQWNPVAE"
FT   CDS             join(complement(26318..26354),complement(26205..26258),
FT                   complement(26078..26166),complement(25825..25973),
FT                   complement(25706..25785),complement(24495..25663),
FT                   complement(24185..24448))
FT                   /note="02.04.2002 prediction extended (V.W) by 4 N-terminal
FT                   exons, this identified FHA domain; 07.03.2003 additional
FT                   intron 25664..25705, and exon extension 25974..25988 (pers.
FT                   comm. Chahwan)"
FT                   /gene="nbs1"
FT                   /gene="SPBC6B1.09c"
FT                   /product="FHA domain (phosphopeptide binding); low
FT                   complexity region (C-terminal); similar to human NBS1
FT                   (pers. comm. Chahwan); no apparent S. cerevisiae ortholog;
FT                   involved in DNA repair (predicted); involved in cell cycle
FT                   checkpoint (predicted); localization nuclear (predicted);
FT                   Mre11 complex (multisubunit endonuclease) (pers. comm.
FT                   Chahwan)"
FT                   /protein_id="CAD88196.1"
FT                   /translation="MWIIEAEGDILKGKSRILFPGTYIVGRNVSDDSSHIQVISKSISK
FT                   RHARFTILTPSEKDYFTGGPCEFEVKDLDTKFGTKVNEKVVGQNGDSYKEKDLKIQLGK
FT                   CPFTINAYWRSMCIQFDNPEMLSQWASNLNLLGIPTGLRDSDATTHFVMNRQAGSSITV
FT                   GTMYAFLKKTVIIDDSYLQYLSTVKESVIEDASLMPDALECFKNIIKNNDQFPSSPEDC
FT                   INSLEGFSCAMLNTSSESHHLLELLGLRISTFMSLGDIDKELISKTDFVVLNNAVYDSE
FT                   KISFPEGIFCLTIEQLWKIIIERNSRELISKEIERLKYATASNSTPQKIIQPQRHIQKN
FT                   IVDDLFSVKKPLPCSPKSKRVKTLENLSIMDFVQPKQMFGKEPEGYLSNQSNNGSAQNK
FT                   KSGDNSEKTKNSLKSSSKKSANTGSGQGKTKVEYVSYNSVDKGNSSPFKPLELNVVGEK
FT                   KANAEVDSLPSENVQESEDDKAFEENRRLRNLGSVEYIRIMSSEKSNANSRHTSKYYSG
FT                   RKNFKKFQKKASQKAPLQAFLSLSEHKKTEVFDQDDTDLEPVPRLMSKVESIPAGASSD
FT                   KSGKSSISKKSSNSFKELSPKTNNDEDDEFNDLKFHF"
FT   misc_feature    complement(24449..24466)
FT                   /note="ctaatctttttcatacag, splice branch and acceptor"
FT   intron          complement(24449..24494)
FT                   /note="confirmed intron (pers. comm. Charly Chahwan)"
FT   misc_feature    complement(24489..24494)
FT                   /note="gtatgt, splice donor sequence"
FT   intron          complement(25664..25705)
FT                   /note="confirmed intron (pers. comm. Charly Chahwan)"
FT   intron          complement(25786..25824)
FT                   /note="confirmed intron (pers. comm. Charly Chahwan)"
FT   misc_feature    complement(25974..25988)
FT                   /note="splice branch and acceptor"
FT   intron          complement(25974..26077)
FT                   /note="confirmed intron (pers. comm. Charly Chahwan)"
FT   intron          complement(26167..26204)
FT                   /note="confirmed intron (pers. comm. Charly Chahwan)"
FT   intron          complement(26259..26317)
FT                   /note="confirmed intron (Pers. Comm. Charly Chahwan)"
FT   intron          26756..26876
FT                   /note="possible intron in 5' UTR of prp17; predicted by
FT                   HMM_intron, Score=9.30"
FT   intron          26941..26984
FT                   /note="possible intron in 5' UTR of prp17; predicted by
FT                   HMM_intron, Score=13.64"
FT   CDS             join(27086..27196,27238..28002,28042..28657,28701..28748,
FT                   28788..28924)
FT                   /db_xref="SPTREMBL:O43071"
FT                   /gene="SPBC6B1.10"
FT                   /gene="prp17"
FT                   /product="WD repeat protein; putative pre-mRNA splicing
FT                   factor; complexed with Cdc5p; similar to S. cerevisiae
FT                   CDC40"
FT                   /protein_id="CAA17053.1"
FT                   /translation="MLVANYSSDSEEQENSQSPNIQPLLHTENLAPAVVDNVKDDLIVS
FT                   KGGNSRELARNVPVNEMVQPALGPANPFVTKEQDSIKNSITGYAEREYVPNFVFNQEYY
FT                   ANTHAIYGKRNFDDNEATTSTDLKRKSQKIKERREDPGDPSILEGDGAYKGPWAGYGSE
FT                   QSSSPLEYSEYEEVESLDVKSEKDTESNNLGQNELLKEQLATPEVETHRSKEETILHKD
FT                   RLFDYQNRSYMHVPNDVGINLSEEPGEQTCYIPKKHIFTWKGHTKGISCLRFFPISGHL
FT                   LLSGSMDNQIKIWEVYHDRSLLRTFQGHARPIRDLSFSQDGRSFLSTSFDKTIKLWDTE
FT                   LGKCLNCFNSDRLTNCVKFQVDPDKPNEFLAGTADKRILQFDIRSPDIVQAYDHHLGGI
FT                   NSITFLENGKRFVTTSDDSSMRFWEYGTPVPIKFVADIAMHSMPRVALRPNGKSIACQS
FT                   LDNCIYVYSAYEKYRQNKKKVFKGYSCSGYSLEVGFSPDGRFVFSGDSSGNACFWDWKT
FT                   CKLMAKLPAHSGPVQSMAFHPQETSKVATSSIVDGSIKYWD"
FT   misc_feature    27197..27202
FT                   /note="gtattt, splice donor sequence"
FT   misc_feature    27225..27237
FT                   /note="ctaatcattttag, splice branch and acceptor"
FT   misc_feature    27629..27730
FT                   /note="Pfam match to entry G-beta PF00400, WD domain, G-bet
FT                   a repeats"
FT   misc_feature    27761..27859
FT                   /note="Pfam match to entry G-beta PF00400, WD domain, G-bet
FT                   a repeats"
FT   misc_feature    27851..27970
FT                   /note="Pfam match to entry PF00400 G-beta, WD domain, G-bet
FT                   a repeat, score 33.60, E-value 4.5e-06"
FT   misc_feature    27983..28099
FT                   /note="Pfam match to entry PF00400 G-beta, WD domain, G-bet
FT                   a repeat, score 34.70, E-value 2.1e-06"
FT   misc_feature    28003..28008
FT                   /note="gtatgt, splice donor sequence"
FT   misc_feature    28031..28041
FT                   /note="ctaatatttag, splice branch and acceptor"
FT   misc_feature    28241..28357
FT                   /note="Pfam match to entry PF00400 G-beta, WD domain, G-bet
FT                   a repeat, score 13.90, E-value 0.78"
FT   misc_feature    28501..28524
FT                   /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
FT   misc_feature    28637..28759
FT                   /note="Pfam match to entry PF00400 G-beta, WD domain, G-bet
FT                   a repeat, score 20.00, E-value 0.058"
FT   misc_feature    28658..28663
FT                   /note="gtatgg, splice donor sequence"
FT   misc_feature    28687..28700
FT                   /note="ctaactagttttag, splice branch and acceptor"
FT   misc_feature    28749..28754
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    28775..28787
FT                   /note="ctaacatttttag, splice branch and acceptor"
FT   CDS             complement(28985..>30830)
FT                   /codon_start=2
FT                   /db_xref="GOA:O43072"
FT                   /db_xref="SPTREMBL:O43072"
FT                   /gene="SPBC6B1.11c"
FT                   /gene="fab1"
FT                   /gene="SPBC3E7.01"
FT                   /protein_id="CAA17054.1"
FT                   /translation="TQNTFPASPVSNSGFSRQTYPNISQRQGVNMLSHKRKSASTSDRR
FT                   FVNASSTSGMNMPISSSISAKISSIQNSTKYSPRKPIPAKDVRVSSLVRRFEELSLQLQ
FT                   EKQKRDEELIKARRKRALPVVPSKPVVEVFNDLNEAFDDENSEDENGINDTKENRATES
FT                   NFSGVDSMSKERENVSSNEDNSPEAFEDIFGILFKNESGLEEQQNLEPSSQMDKEGSKL
FT                   PTSGPLADKTSVYRILSAFWNEWNSLNPPPFEFPLQPTEHMFSDSNVIIREDEPSSLIS
FT                   FTLSSPDYLSKMVEIEDSMDEALTNQGLQGSTQFKIENLMLKPTGTHLKYQFEEGSARL
FT                   SCKVFFAEQFSALRRACGCEETFVTSLARCSLWESSGGKSGSAFLKTFDKKYILKVLSR
FT                   LESDSLLNFAPAYFDYISKVFFHELPTALTKIFGFYRVDIRNPTTGTICKTDIMIMENV
FT                   FYDECPSRIFDLKGSMRNRHVESTGKVDEVLLDENLVELIYESPIFVSEQLKSLLHSCL
FT                   WNDTLFLSKLNIMDYSLIVGIDYTKKELYVGIIDFIRTYTWDKKLESWVKEKGLVGRGP
FT                   EPTIVTPKQYKNRFRKAMDCYILASQDFETGEGFKFCE"
FT   misc_feature    30774..30830
FT                   /note="nominal overlap with cosmid SPBC3E7, EM:AL023534 S.
FT                   pombe chromosome 2"
XX
SQ   Sequence 30830 BP; 10033 A; 5556 C; 5359 G; 9882 T; 0 other;
     atcagaccga ctttgagcag taaagttata gtctgcacca gtttttttat cagcagacga        60
     agttgagttt tgctgatgta ctaaagttgg agcaacatca ataacacgaa ctttttgtga       120
     atttttcatt tgtctagctt tacgctttaa tgcattccgc tgacgagcag ataaatgaac       180
     gttttcggaa ggagtcgggg tatcttccgg tttattatta ttgatagaag ttttatgttc       240
     tgggattgaa gtagtagggg aacccttgga attggaaccc acattatctc ctaaatcatt       300
     cattatactg tcatctagat actcgccagc aagatcgaga cgacttttca aattagaaag       360
     ttgttgtaaa taatgtgtag aataatttgc aggattaaca tcgtaatcac ggctagcact       420
     ccctaataac tttttaccag ctttgagaac atttgctatg tcaaaacttt caaaagataa       480
     caacgaattt tcaaattttc ctttaagctc agtatttaac tctttcgctg tttcttcatc       540
     aggaccaaag tcaactatcg gttttatttc ttgtgaatgt gaacgagtag aaagcctctc       600
     ctcttccagt tttgatactt cgctattaga agttaggttg gaagagacga caacttggga       660
     ttgtgaagat gctggagcgc cttcctcggt ttttatgaac ggtttttctt cagtgtcacc       720
     attgaaagaa ggcaaatctt cagtttcctc cttttttacc ggagacgtcc tatttggatt       780
     ccatacaggc acattttcca ctattccacc gatcgctttg gcagcagcaa cacgtgtatc       840
     ccagttttta gatttcaagt atgggacgac tcgtcccaat agattgtaaa gctcatcagg       900
     atgaactttc tgtatatctc caatttgttt agcagctgtc tctcgaacga cagaagtaga       960
     gccgctatca agcaatacaa ccaaccggtc gaggcgtgtt gtcatatgtg aaattaaaga      1020
     aaaagaagct tttcccaaaa gatcagttta attactcact taatatgagg ctcaaattac      1080
     acctcccaaa tataaaatta acaaacaaac aaaaaagaaa acagtgctta aaaataataa      1140
     taataacacg aaggattcaa ataaaaaacc aggatctcta taattgaaaa taaaggtttg      1200
     tttacagcta gctgtagact gatgatgagc gtagtacctg tcaataaaca cgtcggtaac      1260
     caaatttttt atcactatac taaaaaaccc ttattgaatt caaccgtgga aataatagag      1320
     cataattctt ttaatgttta ctaatttgcc gctttcaatg gctgcaaaag ccatcgtcag      1380
     ctgggaggct ggtggtactt atgcgatttg agaagccatc aaaacgtgaa aaaagctggc      1440
     aaaccctaac ccacacattt acttatatga gtagttgcaa attttataat gcaatttgac      1500
     aaaaaatatt gaaatgaaca tgcttataca tttatactgt gtacttaatt gtaaaaatgt      1560
     tatgacccac tagtcatatg ttatgtctat gtattttgca accttggaat gattagttca      1620
     aagaaagcaa acaacgtatt ctcgcatcgc gctaagcatc gttactttgc attattatca      1680
     atttgcttat cattttgctt attaagtata gaacaaataa aattcttatg aaatttctcg      1740
     tattctaaaa aatgaattaa ttcccgcttt aaacaagatt taacaccgtt taaagttcct      1800
     aaaaacggaa cattgcaatt gcgttctttg aaggatagtg atggttttcg gtaaatatta      1860
     ttcttattgt gcaccctaca cagattgaca aataataaaa ataatcaagt acgataatga      1920
     tgcttctgat aattggtgat tcgacgaagt ttaccaattg tccaaattac cagcgtctgc      1980
     taagcttttg cgcatgaaag atgtgttacg aatattacaa gtgaatacaa gaaaaagagt      2040
     gtttctaaag aagagtaggg ttaatgaata gttgcagtct attatcgttt tgaacgcaga      2100
     gttgtttagt agaaaacaaa aaaaaaaagt ttacatattc ggtaaaaaaa tgtatggatg      2160
     ctatgggcac caatagtatg cataaggtta actctttgta ttgcagctaa agatgtagtg      2220
     aggacgtcaa tatttgcaat tccgcatctg aacacaggaa gtctagcaaa ctcttaaaga      2280
     ctttttatta taaaccaaaa atgagtgaga atgtttttct tatttttatg tttaaaaagt      2340
     aaaaacaaaa aaactcttga aatattaacc tttaaacaca taaagtatat actacttgta      2400
     tagaaaacgt aatgttccct atcactttta cagttaaaaa atgttgaatc aaaatttgaa      2460
     tatgatagta ataccactaa aaacttaatg ttaacaaaca actactttta attgatgaat      2520
     ttacttttat aaattgctat ttgatgctat tatgttttca ttataatatg ttttacggat      2580
     tgatcggtaa gttgcgatac acggtatgtt agattttcat gaaccgattt agtgtcattt      2640
     cgcttactcg ttatccgaac cgtttccgca tcaagctgat atttaccata acaagacctc      2700
     acggttaagt cgctatctcc gttgcctccc ttactgacag acccaaaacg cacttgtcaa      2760
     gttggggctt actcttccat tgtgagtttt gttctttctc ctttgcaatt aattgaaagt      2820
     attaatcgct agttaagcta taaaggtttt aattacccaa cgttgtgaag agtaaccaaa      2880
     cgtactttgt gaaatttcat ttaatagaaa accggttgct tcaatttgta tattcttctt      2940
     ttgtacaaaa ttacctttca tttctcattt ttaattgcat caattaaggt tcctaattgt      3000
     ttgtttggaa ttccattatt gttctaattg catatgacag aagtctactc gaaagcaccg      3060
     gctaccgtag gccaagtcaa attatcaaac aatggaactt ctaataaagc ctactcagtt      3120
     ccgaaatctc cagctccggt aaggactgat ttgtttagta agattccagc tggtactaaa      3180
     attcaagttg gctcacacag tgtcattatc cagcgctacc tcagtgaagg cggattttct      3240
     catgtttatc ttgctttatt ggaaaatgag aaaccctttg ttttaaaacg tatatatgtc      3300
     cctgataaaa ctgctttaca acttgttcat ggagaaattg agacgatgaa gcggctaaaa      3360
     ggtcatcgtc atatagttaa ttatatcgat tcaagtgcac tttattccaa atcagaaaat      3420
     cgttatgaag tctacttgct tatggagttt tgtgctggtg gtggtctgat tgactttatg      3480
     aatactcggt tgcaacatcg gttaactgaa ggcgaaatat taaaaattct agcagacgtt      3540
     tgtgatgctg tagccgctat gcactactta gatccccctt taatccatag agatttaaaa      3600
     attgaaaatg ttttgttggt ggctccgaat tcttacaagc tttgtgattt tggaagtgca      3660
     tgtgaaccat tggccccagc tacaacgccc gacacaataa tgtttttaga gcaaaatatt      3720
     gctgcttata ctacacccca gtaccgagct cctgaaatga ttgatattaa tagaaggcaa      3780
     ggaatagacg aaaaaagtga tatatgggct attggtgttc ttgcatataa gctatgctat      3840
     tatacaacac cttttgaaca ggttggtaat agtgcaatac ttaaggcttc tttctctttt      3900
     ccaccctttc cacgatatag tgataggatg aagcgtttca tagccacatg ccttcaagaa      3960
     caaccttccc atcgtccaaa tatttaccaa actttgaaag aaattatgga aatgcaaggt      4020
     acacctctga aacttcctga tgtatatggt ggggtcaatg cctcaactta caatcctcca      4080
     agagctcctc ttcagcgaac tccttcagga agccttactc cgctgagttc tcgtccagca      4140
     catacgtctc ttcctcctat tccaactgtg caaacgactt cttcaaatgt acccccggtg      4200
     aatcgcccat ctttaaagtc aaaatctcct tctgtttcta acatcctttc aaatcagtta      4260
     agtcctattt cttctgctaa caatgatgtg atggcgcggt tgcaaccaaa atctccaatc      4320
     cctgcaacaa aaagctactc tgcaacaatt cagacgcccc gttctccttc tttacgaagg      4380
     gctgatagca catctcatat tataaaagtt cctcatttac ccgacacatc tgtgaaaact      4440
     gctaaaaccg gggcatctga aattgatgtt cttagtcggt atcctagcgt ggaagaaatt      4500
     gataaaatta ctgacaaaat tgaggttagt aaaccacttc gcaacagtgg gcctctagct      4560
     ttcaagcctt ttgaaaagat ttctgcgaac aaacagactg atttattaca gaataaacct      4620
     gaagccctcc tagatttaga gaatcggttt ttacctaaac catctcctaa accatccgaa      4680
     ttcagttcgt ctgtgggatc taagcaaaac ttgtcaatgg atattccttc agttcaaaat      4740
     gtttcgacaa aacagaagtc tacaaatgac acagataata gcaaattgaa aataaataag      4800
     cctttaactg ggggatatgc acctctacca tcacgtccga atcgaatgaa tcatagcgtt      4860
     ttaaatgaaa aatctaacaa ggagtttgta cgaggaccaa gagtacttcc gccaatagaa      4920
     gtttcttcct ctaagatggc tggactggat attagaaaag agccttttac acctgctgtt      4980
     cctagcgcaa aatcaggttt aaagaaagac caatctagtg aggttgcaaa taaagatgtt      5040
     gtatcgaaaa acaaggataa catagctata ctggctgata gagaagcacg tccccaactc      5100
     cttcttgacg ataacaatga ctctagctcc tcctcgagcg agcatctcat atcgtttaat      5160
     aatcatacgg gaaacaaaat attatcaagg cagacaacat catcaagcat cgatagtaat      5220
     aatgttcaat cgaatatcga gtttttgaaa ggattgaatg ctactcatgc tcgttcaaca      5280
     tctcaggtat cgcatacaca aagattacag cagtcaattt caaccagctt agaaagagtt      5340
     aagagcaata ccaaaaagga gtctaatagt cctcgtcagg tgtctaaatt gaagcgcccc      5400
     atcggtgctt ctaataaaat tctctctggt aaattcggtg aagcattcaa aaagtttgag      5460
     tttggtgggg agaagatgtc acggagacgc aaaagtgaaa ctaaaaagaa tttagtatcg      5520
     attttacctg acactgaggt cgacgagtat cctaaggctt caaatgaatg gatagttgaa      5580
     agtgaagaac ttccccaagt acatgaaact atcaatcagt atcgaaagtc ttgtgaaaca      5640
     caaagatcac gtaaatcgca tgaaggaagc aatgatctag aacgtcaacc atcttcgcca      5700
     gatactgtgc atccgggaat caagcgatct cactttattc gagagcgtgt gaaacaatta      5760
     ctctctgatg ctaataaaca ccatcaatca ccatctgact cagaaacaga tagaacacct      5820
     gattcgagtt ctattcattt accacacatt gagcgtctaa accttttcca taccaaatct      5880
     gaaagcttgg agtaacacta gcattcagta tttgtttaaa tcgtacttaa tttctcggtt      5940
     gcattagata ccaaagcata tttgtcttct atttttggac gtggagtact ctctttttat      6000
     tttgtccgct gataacttct ttatgaactt aatgatttat ttttaacaaa aaaaaaaaaa      6060
     aagattttat atactactaa tcaactactt gttgtaagta ttgtttatta tattgtctta      6120
     ttcaatattc atcaaccact aaacgaatgc tacttgcatg ttccgaggtt caacagtcag      6180
     tttttactat tttatattat aactttgttc tttggccacc aatttgtaaa taaaaagaac      6240
     ttgtgctttc tatgcacttt gttgattcaa attaaagaat taaaaattgc cttaaaccat      6300
     aaacattttt aatataacat atatatatat atatatatat agtaacatag atactgttct      6360
     gtaaatttat cataacttcc aggtgggtag cgatcatcgc attgcgcaaa tggatttgaa      6420
     gtttcgctag actatgtaat gagcgtaatc caccaaactt aacaattata aaattcaaca      6480
     atcattcggt ttcaatggaa ttacgcttca aatgcttgcg caaacgatag ataaaagatg      6540
     cttttttctt taaattattt tccgtattgt cagtcgcatc atcgttgctg catacattaa      6600
     tgtctgtagg gtttggagat tcatttgttg atgaatttac gtttgaagaa tcgttgtccg      6660
     tcacaccgtc ctcattttct tcagattttt caacaccctt tgagttatta ggaagtaaaa      6720
     atgctggtaa tgaatttgct tcgctctgac ttgaaaatgc agctattggg ctagtggcag      6780
     catcaagatt tcgatgctta gaacacgggt caaatgggcc atcatggtga acccctaaag      6840
     tttagttaaa aggctgctga gttgcacaat cttaccgaaa tctcctaggt atgaattcga      6900
     agagtccagc ttgtctattt tgtcatagcc tagcatgtta aaactctctt tggaagatac      6960
     ttttcgctcg aatgccttgt tctggttcca aaatggagga ttttcggcca tttcgttaca      7020
     ttctattatt gcaatttttg gtttgatcac cctctttggt ttcgcttcat atattctaga      7080
     attgctacga gaatgcaatt tcagcaggtc aaccccacta tctttattta aaaatggatt      7140
     atttgattgt agttctgcat cgtcttcatg atgttgatat tgattcagat ttatgccgga      7200
     atgcggtcgt tcttcgttaa aaacgtcaat tcttggggag ctaaactata gtacacgata      7260
     tcggttaatt aaccatttat attttttata aaaattatat tttgaacgta cgattgtgta      7320
     ccctttttct ggaatgtctt caaagttatg agtttggagc ggcgggaaat ttgcattcga      7380
     gtgcacaaaa ggattgtttt tccccataat tgaatattaa agtaaaaaag aaagaaagga      7440
     ggacctactt aatgcccctt ggtaaaaatg agacagcttg tttttacact aatgagctgt      7500
     atttattcgt tttttgtact tcgacgtcac aaagcaatca taaaagtcat tgataatgtt      7560
     aggatcattg ttacagagta atgaagaaag aaaacatcaa tagcaatttt tagtagctac      7620
     gcgatttagg actcttttga tgctaaaggt gggcgatcat taatgattta cattatcaag      7680
     tattatagtg tcgacacaaa ctgcgtgtat ataaatgtag tagtactttg attaaataaa      7740
     agttctttta gttagttata aatgtgttat agttaaaaaa tgttatatac cattttaaaa      7800
     aacattcaat gtcagtattt aatgtacaga ccatgctcga cttagatata cagtctttgg      7860
     aagttttatg aattacaaaa aaggagaagc tgtgattttc atttacaatt atttcctgtt      7920
     taaagtaact gtatttgaag tgatgccaat atttgcatta ttagtctaaa ctgttcaaaa      7980
     tatactttcg aatggtagca atatttagaa aatgtttatt tattcgtcct atttagttta      8040
     tattaatttt accgtatgat tatgcatact aaatcgagtg ctaatattca tttattaaaa      8100
     taatacttca ttaaaccaat ttcaacacct aaaaaacaaa taaatataaa tttgagtatg      8160
     ttggttagtt aatccaaata tttcagaatt ttgtttgttt acgtatcttg aatgaatttc      8220
     aggactgaaa cagacctaat atacactgcc ttgataacag cgtataagta aaaaagttgc      8280
     aaattctaaa taagaaaatt tggaaagctt tcattatatg ttaattgttt attagtattt      8340
     atgcgtaaca ctttcacatt atagtgccaa accaaaacct tcctagaact gtaaaacgga      8400
     aatttttcat tttcttgttg tctttttttg gtttaatctt tttgcatact caaaatacta      8460
     ggaaatgagt accatttcca cgtctactga ttcaaaactt gataatttag gattaagtgt      8520
     tactagtcgt cgcaatcaga ttttattcta tctttcaaaa gcactgaact tagctcattt      8580
     acttcgctcg gattctttac aaaaatcatt tttggacgca cttaagcaat ccgctactga      8640
     ttccgaattg ctacataaaa acctcgacga aattaaattc ctgcaaaatg aaaaactcaa      8700
     caacgagaaa ttattagaac aagaacaaaa tgaagcaaat gattacaggt tgaaagtcga      8760
     acggctggag cacaaaatct cggattatgt gcaggaaatt aactccttga attcccagtt      8820
     gcaaatccaa aaatctaacc ctgaaaaaca tgaggatgca gtgtctcaaa ataggttacg      8880
     aggttcctta gatacggttt cttctccttc aaaaacccac aaagctaaca aagatgaaaa      8940
     agctacaaga cttcatttga ttattgcaaa tttgaaaaaa gctttaaaag aaaaagacgc      9000
     tgaagtttta aatcttcaat cacatgtatc ttcgaaggag tctgagcttg atagatttaa      9060
     gattaaactg gaaacagaag agtccaactg gaaggttcga ttgcaagtcc ttgagtcgaa      9120
     actggctacc caggatagga agctgaggat gcaaaaaaag agtactgaga gaaagagttt      9180
     acttgtttct cctcgtgttt cgtccccaaa acttttttcc ccttcgaaac aggcaattat      9240
     gggtactcga caaccaaatg caacttcagg atcccccttg agcgttaccc cttttcttca      9300
     aaaaacttct acttctatag ggctatcttc tagtccgcct caatcatcgc catcagctca      9360
     gtcctcacag cctttttcgc gtgacaagta tccccactcc atgaccgtaa gcccatccaa      9420
     tgctcgttat cttaaaaaac acttagacga taccatccct tcaaatgtaa gtgatattaa      9480
     tcataatgat cacttaaaaa taccacaatc cccatcatca ttgagtcctt ctaagattcc      9540
     aatcagaaaa aaaagaaagt tgaaggatac tgtttctaac tgtgaattta cagaagaaga      9600
     tagcgaatct agctttctat tagagacaat acaacctact aaaagtacat tacgacgctc      9660
     aataagtccg ttaaaaaaaa gaaatgatga gataaatgaa ttgaagaaag gatttacaat      9720
     gaaaaaataa attaaataga ttttgtctaa cacttcatag atttttcaat tatcgatttt      9780
     tccaaacata gtttaattca ttagtatact ggtccataac acacgccatt aaagaatcac      9840
     actttcttta tcactaatcc attcttccat tgtgccagca atttcaccta atgcttgtac      9900
     ttctcttaat ccacataatt cttcaacata gtccggttca ttaatggctc gtaaaacaaa      9960
     catccatttc tctctgttcc attcatttat aatacattca ctgcaagctg aacactgagg     10020
     ataagccatc cctgaaattt tcattaggct aaaattatgc aagaaccctc gaatttgatg     10080
     gggaagttca cctaacacag tttgatcttc atttaagaca ggtgcagcat gtctaaaatt     10140
     gataattaat aattctaaaa aaaatttccg tacccattgg ggtgctgcag caagctaaca     10200
     aataactcta ctgctattgc tgtagcaatg ttagcacatc ctgatcgtgt tactgtgcag     10260
     gtctgatcaa gtgtacggtc aactagtgag tttgaaggcg caaatatgtc attacaaaaa     10320
     taacaaccta agcgattctc tttttgtaaa acactaccat gtctcatgac cagccagctg     10380
     tcaaatccta atgctgaatt gatcaacaac ttgtccatgg cagttgatat gactgtcgga     10440
     agccaacgtg attcccttgt atcggtcaac aagaatatcg catcgtgagt ggaaataagg     10500
     ttctcaagag tttcgtaatc atgcatagtt ttctcaatgc cagcttcata tatagggtgt     10560
     ccaagcattg gtatgctgat gttatatccc gttgaaaact tctttgttag cttgcattca     10620
     taataatttt ttgtaccata ttcgggtata tctccttaag ccgttgcgcc gcacactctg     10680
     cctttggcaa ctttcgtttg caatcttcaa atgtaaacaa tgactggcgg acaggatttg     10740
     agtaggagac agtagagtaa tccacaaatg taacatgtct caccccccac gactagaacg     10800
     ttagcaattt ggtcgtttgc ttcatataaa tattttattt caatttcatt accagcaaat     10860
     tccttgccac tccacaaccc agagtaccgg cccccagaag taaacatttt gagttttgaa     10920
     tacgatcgag atctaattgc ggcactagtc tccatctcat caagcttagg tttaacgttg     10980
     aagcagattc agacaataca aaaggatcaa ggaccgtaga caaattaacg acccggggac     11040
     ctaaaacgcc ttttccattt ctttcccatc caacgattga aaggggtgct tcaagaatca     11100
     tatccttatc tgcttcaact tttattagta tgcttttcga cagcgtatca gaattaatcc     11160
     catcgcgata tagaaataaa ttaatcactt tcaatttaaa cttaataaat gcaaaagcga     11220
     ggatattcct gactggccaa gatggatatt ctgccaattg aacagaatct tctgcaacga     11280
     gataaaacta cgtgttagtt ggattaaaaa tcgatggcat acctgaagcg acttgtccac     11340
     acagtgggaa agctccttca gaggtgcaat agtccattca tctaatgttg attttattaa     11400
     taagaaaaaa gggcgttgat agtaatcagc tgtagacaag aattcacgaa tttgagataa     11460
     aattggacct gaaggtatta gcgattcagc tggtgataag tcttttacaa tccagtgagg     11520
     agtttcttta aacgaaggaa ataagcacca ataatggtat ttgtaagctt ttatgtcggc     11580
     gtaagaaaat ataagaaatc taagtaattc attaggcctt tcagaaacaa ctccgttttt     11640
     aattgaattt aataactata cataatgtta atgagctttt gtatcaatct acttacaact     11700
     tcaccaattt cctctcgaat ttttttcacg tcagcgttag taaattcttg aggagtattg     11760
     gcatttaaca gtgtaccctc ggctaaacag tctttgatat tactagggac agattagatg     11820
     aagcattatt gtacactcat tacctgtttg atggcgcttc tccaaataca attgatatat     11880
     ttcctcttga atatgtatta aatttaccat gaatagttaa aggtgacgcg tctaattttt     11940
     gcttttcgac tttgtaattg ctcaattgat gccaaaacgt agcatcaatg gaggaatgga     12000
     atgactgaaa ctgcaatgcc tttccaacaa acatttctga acgttgctac aacgttagtt     12060
     tgctacacag ttactatata ctgctgggta tacacagtaa gtagtgtagt aaattataga     12120
     tgtcattaca tgttgaagcc gtgaactgtt tatcactgtg ctttaaattt cgttaaatta     12180
     gaaattattt agggcaagtc caatttacac ctgcgttatt acagaatata ttgaatattg     12240
     caaatatgct ataattacat tggtgtcagc aatactacac tacgttgcgt atcactatat     12300
     gtcacatgtt ctaattatat atcgtaccat gtatgatacg atatggagat tgatcttaat     12360
     gataatctat taagatcaat attatctgaa tactataaat agagctactg ctgaacctcg     12420
     ttcctcagtt cagttatgag ctatattagt gataggtaac attataaccc agttaataca     12480
     atacctatac tcagttgcta cttatacaac ctgtgtattg taatataata gatcacaagg     12540
     aaaactcacc gcagttctac gtatccttaa atcagatacc aaactgcgta gcttacaatt     12600
     gggtttcaga tatattttca aataaaatga atgtcagctc tcttatgtat ttagggtcaa     12660
     atttacatat tttgaaactc ttgaccgtgg agacgatata gcatttaatt ggaatggtgc     12720
     gtggatactt acaatcaaaa ctactctttc aaaatttaaa atacgaaatt cgttcacaga     12780
     aggtaactca aaatgctatt aaggatattt tttatttatt tcaaatattc ggggagtgat     12840
     gactgtaaaa cgacttttgc gtcaaaggag tttttaaagc caaactgaat ggttggtcta     12900
     ttttgtaaag aaagacttaa atccgggtct ctttgataat gtaatgttaa aaaaatttag     12960
     ttgttgtatg ctaccaaatt ctgctcaacc caaaattcaa taagacgctc cgatgattgc     13020
     tattaaaaaa aaaaaaatga tataaattaa tgtcaatcta gcctttcaaa aagatagaca     13080
     tatccggtag tttttgcttc ttccaaggag gcaacttgaa gcaccttttc atcattaaac     13140
     aaaacccatt gctgctttcc atctatctct ttgcgtataa atgctacata atgaccggca     13200
     tgcgcacttg agcccttatg gcttattatg gcctttaaat tgtagttgac tggaacgttt     13260
     gtcgattccc aactacccat attttcattt tttattgaag aatctgatcc ttcaagtggt     13320
     ggttcttcaa aactttcatc cggatgattt aaaatccaat caactgcgcg ctcaatatta     13380
     ttgttagatt caagcaatcc ttttcgtgct tgtgcaacag taaagccgaa ttcacataat     13440
     gattgaacat tttcttctga aacacttgag tctgctttgg gcagtaattc agaaacttca     13500
     ataggtttgt caatttcagg gtcctccata tgttcaaata gccagttcat ggcagtttca     13560
     gtatcagaat ttccagtagc gagtaatgct cgttggcatc tgactaaagg aaatcccata     13620
     gcttgaagct gttcaatagc actttggttc cattcaatgg tctctgtctt ttcaggaaga     13680
     taatcttcgt catttgggtg gtccttagcc attaagcgat cgaaattata aattccgtct     13740
     tcattaacta ttatagggat gcttaatttc ttaacttgat atccctgtaa atcaaaccgg     13800
     ttggcttgta ggatcaagac tttcgggaac gacttcatgg cagtagtagt tgtagctcct     13860
     agtttacttt tacaagcttc acaagtatac tccatttggt ctggttgtat agttgcatct     13920
     aaacattggt ctattgagac ttcttcataa atttgctcac cctcaatttc accaatttta     13980
     acacgcggaa ctgtcaaagt caatccctga gaagagaaag aagaatagcg aacgcgttta     14040
     caggaaagac aagataattt ttgctccgtt tcaaagtcaa aaatcttagt aatgtcagtt     14100
     ttcgcaatac tagatttccg tattttcccc agcaaataca ataaaaactc ataagcatct     14160
     tgctgttgag aagttccaaa ttcagaatgc ccttgtccca caacatcttt gaacataaaa     14220
     ggcctcaaac catcttggta aggaagaatc gatgaagaag gattattgag taaaccaatt     14280
     ttgctaggtt tagaaaattt cccacttact aaaccatcag ctagtttacc aagttgacat     14340
     tgcaaatctg tagtgggggt ttgacaaaca gaattataag tgttgaaaag gtttaattcg     14400
     tgaatagcaa attccttaat agaaaacaac gactgcatag ttgaggccag ataacagcta     14460
     ttaccaagat ttttaagacc agttaatcct ggtccaaaca atctttttga agcgtcatcc     14520
     tcttcggagg caccaaaatc ccaatttaaa ttttgctcta attgtagttc agccaaagat     14580
     ttttcagttt tgttcaactt ggcgatatcg atgccgaaat ttagcatatg tgtctttata     14640
     tttgggtcaa ttctttcctc atcgcaacta taacaatata tatcagcctg accatcaggt     14700
     gaaatgcttt tgagtttaac tgcaagcgga tgtcctgtat catcataatg agaaagggcg     14760
     tgcccattcc caccacctcc tccgtactgt tttcttccac agcttaatgc gccacatgtt     14820
     aaacacatcc atagattttc tgcaagatca cattttgaac atgtagcatt gtccaaattt     14880
     gtgacgtaag tttcattttc tggtaaattt attatatgat cacaagtagt taattcattt     14940
     tcccatgcag ttaattgact tttgtttgat gccttggtag catttttcat tgcctctaat     15000
     gataacgaaa gtaagggatc ctgtatatct aatattatat tacagaccaa acacttaggg     15060
     acataaaaat aatcatataa atcttcatca ctatcttctc tgatctcaag tttcgtaatt     15120
     ttttggggag gctcatcatt aattttttgc ttaggttgcc tggcaatggt gaccacaatt     15180
     gggtgcaaag tttgttcaaa atggacaagt gagtgtttta acccagtttc cccacatcca     15240
     gattgaaaac aggttaagca taaatcaatt ccaccttctt catcctaacg tttgttaacg     15300
     aatttgaact cctctgagta catgttttaa aacaagctat ttaaaaaaca tacctgcgaa     15360
     ttaaagcaac ggacgcattc ttcacgatat attacctgag aattatctgg gattacaacg     15420
     tttgtctctg tgaggtgcgg acacgacatg ggttgctata ggtgtttatg gatggatgga     15480
     catgaggtag gcagaatatt aacattagtt aataatatac gtgcatcttg ttgattaacg     15540
     tatcgctaca actaaaatac catcatgttt tacagagggc ttaattaata ctcctaatcc     15600
     tgcataccaa actcttatta attcgtttaa ttataaacta aattgcagta cgttacagta     15660
     ctgcaacgag taatatcatt ataactcaat tttccttgtt tgtagaactc cagaggtcca     15720
     ataattgaac atcctggggt tattcttttt attgtgtaaa taaattaaaa accaagaata     15780
     ctgtgcatga actattacca tatttagact tccgagtgca gatgtatgct gtcgagtcta     15840
     cctatactgc tgattagata ttgcttatta aaacaacatt tgtatcattt cctgtaagct     15900
     tgcattttta tattgaatat tcgaatagaa tactcattgc tgtatccatg tattaacgca     15960
     acagtggaca gcgtaaataa cattggcata tataatgtta tcaagcagga gatttgtaga     16020
     aacagcttat ttacacagtc ttaaaataac aatagttaat taatatttct tgaatttttt     16080
     ttatgataag tgaaaatcca cacatcagat tctactatac tcactcaagt tgtaaacaga     16140
     tggttaatat acgctgtatt tattaaaata tcattctgaa tatatcatta tcatttacac     16200
     aggtactcct gaaatttata atattaaaaa aaaaaaaaaa aaaagagaaa aagatacagc     16260
     tagattagct gccgtatttt ctttaaacca aatttattta cacactacat acataattca     16320
     tgcctatatt tataaatgga ataaaataga acaattttaa tacccaaaat taacctggaa     16380
     aagctaagtt aaaaatgaaa cgagccatat atattgccga ttattatcat attttgatat     16440
     cagtgttttg cagatgattc taatctaaca tatctgaatc ttttattctt ttttgtgaaa     16500
     ctgacttgct tgcatcttat ggctggagtc agtataaatt tcttagaact tatcaatcca     16560
     acgaatatac ttctaaaaga tattacatta gccttgcaca acctgcagtt ataatcaaaa     16620
     cacttaatca acgtagctca agcatgtcta tttaagatgt taaatatgtt ttggtaaatt     16680
     actttgcaaa taaaattcta aatacaatgg tttggcatta tgataaagaa taagacaatt     16740
     tacaagcgaa aataaatttg actgatgtgt ccaggtacac tcatactaga tacgatgagc     16800
     attgatttga aacaccagta taatataccg agacattaaa agacaaacgt agtggccatg     16860
     caaaaatatt gctgcaacgt ctgtccagtt atcactcgga ttcaattaag atttgtttaa     16920
     ttccaatact cacaaagctt gtgatgaaca atatttttcg taatttcaac cgttctgcat     16980
     actttacacg acattgattt acaaagtgta aattcatctt caaagaaaag taggaaaata     17040
     aaagaaagga agaaaacact gttcatgcat tttttcaaaa ttgttgcaaa aaatctaata     17100
     aatttatttg gctatcaaat gctaaatcat aaatactcgt gtgttagcgg ttcagtgtat     17160
     aacaagtcaa tcacaatgct tatttatata tcgtttgatt gtaaaatcat tacatacagt     17220
     aggaaattta ttttgtttaa gaaatattct atcttaagtt tttctaaatt tacttttacc     17280
     taatggctct ttttaacttt gttgtagtaa agctgctagg agttaatttc tcttcttcgt     17340
     attgcctact tttaaaattt gaaagccact accagatatt tataaagccg aaaggctcgg     17400
     cttattgcat ttaattgcag ataattagaa tggcaaactt ttatccagat tttctgaata     17460
     tgcagccacc tcctaactat gtagcaggtt taggacgtgg tgcaacagga tttacaacgc     17520
     gttcagatct tgggcctgct caagaattgc catcccaaga atctataaag gctgcaattg     17580
     aacaaaggaa atcagaaata gaggaagaag aagatatcga tcctcgttat caggatcctg     17640
     acaatgaagt agcgctgttt gctactgctc catatgatca tgaggacgaa gaagctgata     17700
     aaatatatca atctgtagag gaacatttaa gtaaaagaag aaaatcccaa cgtgaaaaac     17760
     aagaacagct acagaaagaa aaatatgaaa aagaaaaccc caaggtttct tcacaatttg     17820
     cggacttaaa acgtgggtta tccactttga cagatgaaga ctggaataat atcccagaac     17880
     ccggcgatct aactcgtaaa aaaaggacta aacagccgag acgtgaaaga ttttatgcaa     17940
     caagtgattt tgttcttgca agtgctcgca atgaaaatca agctatctct aattttgcag     18000
     tggatactca agcaggaaca gaaactccag atatgaatgg gacaaaaaca aattttgttg     18060
     aaattggagc tgctcgtgac aaagttttag gtatcaagtt agcacaagct tcgtcgaatt     18120
     tgacttcacc atcgactata gatccgaagg ggtatttaac tagtctgaat agtatggttc     18180
     caaaaaatgc caatgacctg ggtgatataa gaaaagctag aaaattgttg caaagtgtta     18240
     ttgaaacgaa tccaaagcac gcctctggct gggtagctgc tgcgcggctt gaagaggtcg     18300
     cgaataaatt atctcaagca caatctttaa ttttaaaagg ttgcgaaaat tgttctcgct     18360
     ctgaggatgt ttggctagaa gcaatacgac tacacccggc tgcagaagca aaagttatta     18420
     ttgcaaatgc cgttaaaaaa ttaccaaagt cagtgacgtt atggcttgaa gccgaaaaac     18480
     ttgaaaatca agctcagcac aaaaaaagga ttataaaaaa agctttagaa tttaacccga     18540
     cttctgtaag cttatggaaa gaagctgtaa atttagaaga agaagtggat aatgcaagga     18600
     tactattagc tcgtgccgtt gaattaatac ccatgtccat tgatttatgg ttagctcttg     18660
     ctcgacttga aacttatgag aatgctaaaa aggtgctcaa taaagccaga caaaccatcc     18720
     gtacttccca tgaggtttgg attgctgctg ctcgtttgga agaacagcaa ggtaatgtat     18780
     cacgggtgga aaaaataatg gctcgtggtg taagtgagtt acaggctact ggtggtatgt     18840
     tacaacgcga tcagtggctt tccgaggctg aaaaatgcga aactgaaggg gcagtgatta     18900
     ctgcacaagc tataattaat acgtgcctcg gtgttggatt ggatgaagaa gatcaattcg     18960
     acacctggtt agatgatgct caatctttta tagctcgtaa atgtatagat tgtgcgcgtg     19020
     ctgtttttgc tttttcttta agagtctatc caaaaagtga gaaactttgg ctgagagctg     19080
     ttgaacttga aaagctgtat ggtacaacag aaagtgtttg ttctatttta gaaaaagctg     19140
     tagaatcatg tcctaaagcc gaaattttat ggttgcttta tgctaaagag cgaaaaaacg     19200
     ttaatgatat tgctggtgct cggaatattc ttgggagagc ttttgaatat aattctaata     19260
     gcgaagagat atggcttgct gctgtcagaa ttgaatttgt gaacaatgaa aatgaacgtg     19320
     ccagaaagct acttgcccgt gctcgtatcg aatcgggaac tgaacgaata tggactaaat     19380
     ccatttcgct tgaacgaatt ttggacgaaa aagatcgggc gttacaactt ttggaaaatg     19440
     cactgaaaat ttatccccat tatgataagt tgtacatgat gaagggtcaa atttttgaag     19500
     ataaagagca gattgagctt gctcgagacg catacttggc tggcacaaaa gtttgtcctt     19560
     attccatacc tttgtggctt ttgctagcca aacttgaaga aaagcagtcc gttatacgcg     19620
     cgagagttgt gtttgatagg gctaaggtta aaaatcctaa gaatgaattt ttatggcttg     19680
     aacttataaa aatggaactc cgggcgggga atatttcaca agttcgtgca gcccttgcta     19740
     aggccttgca ggaatgccca tcttcgggtt tgctgtggac ggaggctata tggcttgaac     19800
     ctcgcgcaca gcgtaaaact cgtgctacag atgctttaag gaaatgtgaa ggcaatgcac     19860
     atttactttg caccatcgcc aggatgctgt ggctggaaaa aaaagcagat aaggcgcgta     19920
     gttggttttt aaaagctgtt aaggctgacc aagataacgg agatgtgtgg tgttggtttt     19980
     ataagtatag cttagaggct gggaacgaag accaacagaa agaagtgctt acaagttttg     20040
     aaaccgctga tcctcatcat ggttattttt ggcccagtat tactaaagat atcaaaaatt     20100
     ctcggaaaac tccgcaggaa ctattacatc ttgccataaa tgtgttatga ttacgacaaa     20160
     aatgatgact gtaacatatt ggatctatta tttatcttaa aattaatgtt taaattggta     20220
     ttcgaattta ctttagatat ttgtaaattt acggactttt taataaaaaa gaacgatttt     20280
     taaacaggtt cgattgaaca cttactttaa atcaacaaga ataccagtta agaaagcagt     20340
     aaaagtgtaa accaaaactt tttatgtaat acacactatc aacacgaaag tgggttttaa     20400
     aaaacacaag ggaaaaactt tcaaaaataa gacaaaaaat tagagaaaaa aaaattaagt     20460
     aacccctttt aagtatatgt tgcctttact cagcaacggg attccattgt gaatatatat     20520
     cccagcgact agattcggct tgacgcgaca catatttgac aaattgaagg acaccttcat     20580
     ctctataaac caaagaaaaa acattccaag cggctggcaa agaaagcaaa atactgtcat     20640
     cttgctgatc acccctatac acagcagcat ctacatcagg atcttcatcg ccaatcatat     20700
     aaatatcata tgcaccattg tcagtattcg caatgcctgt ccccggagat aagcaaagag     20760
     tagcttctag taaagctgtg tcattcgtag tagcaagcgt aaaatcggaa ccagggcgga     20820
     atcgtcgacc aacttgatga aaggaacgaa ggggtaagcc actgacaagt tggatccaac     20880
     gctgaaacgc aggaaggcgc tgcaaatcca tgggcaaaat aatatcaggg ccaaactctt     20940
     catgatctaa atataggtac ctgtgcttat gaggaggaat ggcagttttc caagggaatg     21000
     acacttcgga agaatgcata ggagtgggct gcctttcagc atcgatgatt cgcttaagga     21060
     gagtgtttgc aaattcctga tttaaaaact ctactaaaac aataacagaa tcttgaaaaa     21120
     agcgttttga tagtttttca atgccatcag gtgtcaggta aagtggatta atataattgc     21180
     ttaaaatatc agtatcctgt ttggataaag gttctggctt aacaactggg tagtatgaaa     21240
     accggggaag ttctaagtcc atttgtttca ttgttaaaga ctgcaaagta gaaacggtat     21300
     tgtcgcagta attagcgtca taaccaggtt cgccaggctg agggtaatga aaccagccgg     21360
     aaatagccat tcgaggttta tctacataaa cttcttcaac atcatggaat gaatgtccgg     21420
     gcttaactcg gaagaaagag agttgattcc attgaggagg aatggagtga caaaaatcag     21480
     cagcaggaaa ggatggttgt aatgtaggaa acaaccggag tgcacctcca tattcgggtt     21540
     tccaaccttc gtcaggttct accaagtata agatatagga aatgcacctg gtaccaataa     21600
     catcgtcatg attcatcaaa tggcatcctt ttgagtaaac attaacagac aaatcttttt     21660
     tgctagccga taaagggcca cagccggtaa tcttttgaac gtgagagcga aattcctcag     21720
     agtaaagagc atcacgaact tgacgcaaat acttaagcat gttttgctct ttcttgtcta     21780
     atccatccaa gtttgctaga tcaccagttt gccaaacacg gtaaatatca gttactttct     21840
     ctgtaaaatg tatgttttcc ataagttcct tacgaacatt tcgaagaagt gtatcattga     21900
     tcagaggacg aatcacaaca tgattatacg gtccattttt gtgatattcc cgtgaaagtc     21960
     tttctgcctc actggtatct aatgcatgag gcgcaaatct atccagcact gttggttgtt     22020
     gagtatcccc catcccgttt ttatatttga gatttcacct gaatataatg tgcaattagg     22080
     taaaaatttt agtggttggc aaactcccaa tagtagcaat gaaaagcatc ccacccattt     22140
     ttatggactc gggtctcacc ataggtaaca ttcttgaatt atcgtaagac tttcttagac     22200
     ctcctattac ggagtgactt cggtaactgt gaatttgttt aatgataggg aacgcaggtt     22260
     aattcttcgc ttgcttaaaa caacgtgcta tccgtaattc tgcctattgc tatatatttg     22320
     gatagtaacg cttcgagctt aaagaacagt atagtcccaa aataaggcta aaagagtttg     22380
     aatcttaaac agtaatctgt tttcttttcc attttctgat tagttagata actttctttt     22440
     gatgcttttg aatcaaataa atgaattatt caagatgttt gtgatttaaa gtactatttt     22500
     tttattcctt aaaaaaaccg tagctagttt tattaccaca actcgcattt caggtttcgg     22560
     aaattaatct catttctttt taaaaattaa tattcaataa agggaacaat ttgtttctat     22620
     acttctattt caaaacttat gtctatggcc aaatattgca ttaaatactt tgcctgaaca     22680
     aattgggtta ttgaccccca tataaggtta tagttattag ttgtatagta gtcaagatat     22740
     taataaaccc taagtggggt tattataaag gtcaaaacgc aattcaagca gtctataact     22800
     tacaaggaaa attgtcccaa gtgggggccg aaatcaataa caataagaaa tcccagtgtt     22860
     tgattaaata gtaaaaaaag aaaagaaagt aaattagaga agtacgatta ttaactatcc     22920
     atttaactat tttttccttt tttttttttt tttttttaaa taatatgcta ctgatcgtta     22980
     cgcgcaactt tatggataac ttatactata cttcatgaac tattgtgatt tcctgagatt     23040
     actcgatggc ttttatatct tggtcatatt ttataatcag ttatcccata acaaagattt     23100
     aaagctgtac ggcccttcaa ttgttaatat ctgcatgaaa acttgtttac atttgtacaa     23160
     agcgaaatga tgcactatca aatattgtag aaaattttaa aaattataat tatgtgcaaa     23220
     tgctcttctt ccaagatttt gaaaattgct attaattctt cgacttgcta ataagagcat     23280
     atttgcaaat atatagaatg aggaacgaaa ccgtatcata acataatgaa tccaacaatt     23340
     tttaattgtg taccttttat tatagaatcg ttgttagtaa tatccttatt attttttcct     23400
     ctcactgttt cagtctcaaa tgatccaatg taaccaaaga gtaccctcat gcatggtgca     23460
     tcacttcgac accaaaaaac tagaaaaaca ataatttttt atttttgtgt tacattttat     23520
     tccctccatt tgctgactca ggaggattgg ccaactttag aacgcaggtc ttaatgtctt     23580
     tgagcaagtc cattttaacc gaatcgggaa tactttcagt tgcagactgc aaggcgctct     23640
     catatagctt ttgaaaatca attttagaat cggaattcac aattccccga gtgtagtcac     23700
     gtaattgagt tgtccaaccg caggattcaa gtttgtattc taattcattt gctagcctac     23760
     attttttaaa ttgttgttta gttataaaat ttttttttta aaaaagaaag cctatctttt     23820
     atacctttca taatctccag tttcatatag ctgctcaaca attttctcag tggtcatctt     23880
     tgttgaaaat atgaggtcgt acattgctac gcagaaatat accattgcag atgcaaacga     23940
     aatatttaaa ccagcattga aaagtaacct ttataattaa atcatttttt aatttaggag     24000
     ttgaaaaata aaatatttgg atttcattct gaatacgata tctcaggtaa gtagtcaata     24060
     atagtacaat attattaaaa gtgtagcttc tctatttttt actataaaca aaaaaactga     24120
     ctatcagtaa tgcatttttt gacagttaat aaactacaaa aattctttgg aaataatagc     24180
     tttattaaaa gtgaaacttg agatcattaa attcatcgtc ttcgtcatta ttggttttag     24240
     gagatagttc tttaaatgaa ttactcgatt ttttagaaat tgatgatttg ccgcttttgt     24300
     cagacgatgc tccggcagga atactttcta cttttgacat gagtcttggt acaggctcta     24360
     aatctgtatc atcttggtca aacacttctg ttttcttatg ctcagataaa gagagaaaag     24420
     cttgtaaagg tgctttttgt gaagctttct gtatgaaaaa gattagtcga aattttcttt     24480
     attataccac ataccttttg aaatttttta aaatttttac ggcccgaata atattttgaa     24540
     gtatgcctac tgttagcatt cgatttctcg gatgacataa ttcgaatata ttcgacagat     24600
     ccaaggtttc gtaaacgacg attttcctca aatgctttat catcttcaga ttcttggaca     24660
     ttctctgaag gtaaactatc tacctccgca ttggcctttt tctcaccgac aacattaagt     24720
     tctaatggtt tgaacggaga agaatttcct ttatccactg aattatagga aacatactca     24780
     accttggtct tcccctgacc actgcctgtg tttgccgatt tttttgaact ggattttaaa     24840
     ctgtttttag ttttttcact attatcaccc gattttttat tttgagctga accattgttt     24900
     gattgattgc ttaaataacc ctcaggttct tttccaaaca tttgtttagg ttgtacgaaa     24960
     tccataattg aaaggttttc tagcgttttt actcgcttgc tttttggcga acaaggcaat     25020
     ggctttttta cagaaaataa atcatcaacg atgttctttt ggatatggcg ttggggttga     25080
     ataatttttt ggggggttga attagaagca gtagcatact ttaacctctc aatttctttt     25140
     gagattagtt cccttgaatt cctttcaatg attatcttcc atagctgctc aatagttaaa     25200
     caaaagatac cttctgggaa agaaatcttc tcagagtcat atactgcgtt gtttaataca     25260
     acgaaatccg tttttgaaat caattccttg tctatatccc caagactcat aaaggtcgat     25320
     atcctcaaac ccaataactc caataagtgg tgggactcac tcgacgtatt taacatggcg     25380
     caactgaatc cttctaatga atttatgcag tcttcaggag atgacgggaa ttgatcgttg     25440
     ttctttatga tatttttaaa acattcaagc gcatctggca ttaggctggc gtcttcaatt     25500
     acggattctt taacagttga taggtactga agatagctat catctataat tacagttttt     25560
     ttaagaaaag catacatagt tccaacagtt atactggacc cagcttgtct gttcataaca     25620
     aagtgggtag tagcatcgct atcgcgtagt ccagtcggta tacctgaaag ttgataagaa     25680
     gtgaaaaaaa aaaagaccga agtacctaag aggtttaaat ttgaagccca ctgggataac     25740
     atttcagggt tatcgaattg tatacacata cttctccagt atgcacttaa agttagtaaa     25800
     tcatatatag tcgataaaac ttactttatc gtgaatggac atttacccag ttgtatttta     25860
     agatcttttt ctttgtaaga atcaccattt tgaccaacaa ctttttcatt aaccttggtt     25920
     ccaaacttcg tatcgaggtc ctttacttca aactcgcatg ggccaccggt aaactgtgca     25980
     catattagct ggcattgatt taaaatataa gaaagataaa catataatag aaatgaaaaa     26040
     tgaaaagctc aatatttcca tttaattgga tacgtacgta gtctttctca cttggggtca     26100
     aaatcgtaaa acgagcatgg cgtttactaa ttgatttaga aatcacttga atgtgggacg     26160
     aatcgtctgc aatattagaa aattaacaaa aataagaaac ttaccagata catttcgacc     26220
     tacaatataa gttcctggaa atagtatccg tgattttcct gctgtttagt acgtacaata     26280
     cggccataat gaaattgata tagctagtaa gagatacctt ttagaatgtc accctcagcc     26340
     tcaattatcc acattttttc aacataaaat tctttttatt gaaaaaattc agaaaccaga     26400
     atgctgtttt cacaactgag gatgcatagg tgcgtcgctt ttaattttag tacaattgaa     26460
     agtaacaaag taacccttta tgatgtccaa aagcccttcg ttaaattaga agctaaatct     26520
     actaaaccaa ttcttgaatt tgaattgaca aagcttgctt ttcaaagctt tcttcaagaa     26580
     aaagtttaat caacaaaaac tcttaaaaaa tttataattt caaaaaatta gacttacaca     26640
     ggttctctgt cctagccttg caaacacaaa aaatactgtg agtacactag aaaatgaatt     26700
     tactaaaggg gtaaactatc gtaccaaaat gaaattttta aagtcatgag cttatgtgag     26760
     caaacaaact tcaattaaat actatttatc atacgtcgtg tatatgcact actggataac     26820
     ttcttttaca gtttaaaaaa gtccatgcct ctttaaataa ctaactttat ttctagtttt     26880
     tactacattc ctttattttt taatcaatga attatctatt acctatccta ataagcagaa     26940
     gtatgagtta gctgtagtgt ttcattttcg ctaattgata ttagccagga atctctcatc     27000
     ctcgctaaac ctccctacag cttaatcttc cttaaaccat taccatacga atttgctggt     27060
     ttcatattcg ccgtttgcaa tttctatgtt ggttgcaaac tattctagtg attcagaaga     27120
     acaggagaat tcccaatcgc ctaacatcca acctcttctg catactgaaa atttagcgcc     27180
     agctgtggtt gataacgtat ttatcaaatg ttttttataa catgctaatc attttaggta     27240
     aaggatgatt taattgtttc aaagggagga aactctagag aattagcgcg taatgtcccg     27300
     gttaatgaaa tggtgcagcc tgctttaggg cctgcaaatc catttgtcac taaagaacag     27360
     gattctataa agaacagtat taccggttat gctgagaggg aatatgttcc aaattttgta     27420
     tttaatcaag aatattatgc taatacacat gctatttatg gaaaacgaaa ttttgatgat     27480
     aacgaagcta ctacttctac agatttaaaa aggaagtccc agaaaataaa agaacgtaga     27540
     gaggatcctg gcgatccatc tatccttgaa ggggatggtg cttataaggg gccatgggcc     27600
     ggatacggtt ctgaacaatc ctcttcacct ttggagtaca gtgaatatga agaggttgaa     27660
     tccctggatg tcaaaagtga aaaggatacg gaatctaata acctgggtca aaatgaatta     27720
     ttgaaggaac aattagctac tccagaagtt gaaactcatc gctctaaaga agagactata     27780
     cttcataaag atagattatt tgattatcaa aatagaagct atatgcatgt cccgaatgac     27840
     gtcggaataa atttatcgga agagcctggt gaacaaactt gttacattcc aaagaagcat     27900
     atattcactt ggaaaggtca tacgaaaggt atttcctgcc ttaggttttt tccgattagt     27960
     ggccatttac ttctttctgg ctcaatggat aatcagataa aggtatgttt gtaagcaaaa     28020
     agatgataaa ctaatattta gatttgggaa gtttaccatg accgttcttt gcttcgtaca     28080
     ttccaaggac acgctcgtcc tatccgcgat ttatcattta gccaagatgg acgatcattc     28140
     ttaagtacta gttttgataa aacaattaaa ctctgggata ccgaattagg gaaatgtttg     28200
     aactgcttta attcagatag attaacaaac tgcgtcaaat tccaagtaga tcctgataaa     28260
     cccaacgagt ttttagcagg aacagctgac aaaaggatcc ttcaatttga tatcagaagt     28320
     cctgatattg ttcaagcata cgatcatcat ctcggcggaa tcaattccat aacattcctt     28380
     gaaaacggaa agcgcttcgt taccacatct gatgactctt caatgcgatt ttgggaatac     28440
     ggaactccag ttcctataaa atttgtggct gacattgcaa tgcattcaat gcctcgggtt     28500
     gccttacggc caaatggaaa gtcgatagca tgtcaatctc tagataactg catttacgta     28560
     tattcggcat acgagaaata tagacaaaac aaaaagaagg tctttaaggg atacagttgt     28620
     tcaggttata gcctagaagt tggattttca cctgatggta tggcgttcat tttttattac     28680
     gaatttctaa ctagttttag ggagatttgt ttttagcgga gattcgagcg gaaatgcctg     28740
     tttctggggt aagtgcttgg aattggaaaa acacctaaca tttttagatt ggaaaacctg     28800
     taagctaatg gctaaactcc cggctcatag tggacccgta caaagcatgg cgttccaccc     28860
     tcaagaaaca agcaaggtag ctacatcatc tatagttgat gggtctatca aatactggga     28920
     ttaaaaagat tgttcatatt tcttgaccaa acagcgaaat atatacatta aactaacgtt     28980
     tcttctattc gcaaaactta aaaccttccc cagtctcaaa atcctgagat gctaaaatat     29040
     agcaatccat agcctttcgg aatctatttt tgtattgctt tggagtaaca attgttggtt     29100
     caggacctct accaactaag cctttctcct ttacccaact ttcaagtttt ttgtcccaag     29160
     tgtatgttcg tatgaaatca attattccaa cataaagttc tttttttgta taatcaatac     29220
     caacaattaa agagtaatcc atgatattga gttttgagag gaacaatgta tcattccaaa     29280
     ggcaagaatg caaaagactt tttagttgtt cactaacaaa tattggagat tcgtaaataa     29340
     gttcaaccaa attttcatca agcaatactt catctacctt ccctgtagat tctacatgtc     29400
     gattcctcat ggaaccttta agatcaaata ttctagacgg acattcatca taaaatacat     29460
     tttccataat cattatatca gtcttacaga ttgtaccagt agtaggattt cgaatgtcta     29520
     cgcggtaaaa tccaaagatt ttagtcaatg cagttggcaa ctcgtgaaag aaaactttag     29580
     atatgtaatc aaaataagct ggagcaaaat taagcaagga gtcactttcc aaccttgaca     29640
     gaactttgag aatgtatttc ttatcgaaag tttttaaaaa tgctgatcca gattttccac     29700
     cgctagattc ccaaagagaa catctcgcta gagatgtcac aaacgtctcc tcacagccac     29760
     aagctcttcg caaagcacta aattgttccg cgaaaaagac cttacaggat agtcttgctg     29820
     atccttcttc aaactggtat ttcaaatgcg tccccgttgg tttgagcatt aagttttcaa     29880
     ttttgaattg cgtcgagcct tgtaagcctt gattggttaa agcttcgtcc atgctatctt     29940
     caatttctac catttttgat aaatagtcag gagagctaag agtaaaactt atcaaggagc     30000
     taggttcgtc ttcccttatg atcacatttg agtcggaaaa catatgctct gtaggttgta     30060
     gaggaaattc aaaaggtgga ggattgaggg agttccattc attccaaaat gcagataaaa     30120
     tcctgtaaac tgaagttttg tcagccaaag gaccagaagt tggcaacttt gatccctctt     30180
     tatccatttg actagaaggt tcaaggtttt gctgttcttc gaggccagat tcatttttga     30240
     aaagaattcc aaaaatatct tcaaacgctt caggtgaatt gtcttcattc gaagaaacat     30300
     tttctcgctc cttgctcata gaatcaactc cagaaaaatt gctttcggta gcgcgatttt     30360
     cttttgtgtc attaatgcca ttctcatctt cggaattttc atcatcaaat gcttcattaa     30420
     ggtcattaaa tacttctact accggcttag atgggactac aggaagagcc cgcttgcgtc     30480
     gagcctttat taattcttca tctcgttttt gcttttcttg taattgtaaa cttagctctt     30540
     caaatctacg cactaaagag ctaacccgca catcttttgc tggaatgggc ttcctgggtg     30600
     agtattttgt agaattctgt atactggaaa tttttgcaga tattgaagaa gaaataggca     30660
     tgttcatccc acttgttgaa gatgcattga caaatcgcct gtcactggta ctagcacttt     30720
     tccgcttatg agaaagcata ttaacgcctt gtctttggct tatatttgga tacgtttgtc     30780
     tactgaaacc tgaatttgag accggagaag ctggaaaagt gttctgagta                30830
//