ID SPBC691 standard; DNA; FUN; 11764 BP. XX AC AL590882; XX SV AL590882.1 XX DT 24-APR-2001 (Rel. 67, Created) DT 24-APR-2001 (Rel. 67, Last updated, Version 1) XX DE S.pombe chromosome II cosmid c691. XX KW alpha-adaptin; apl3; atp-dependent rna helicase; DHHC zinc finger domain; KW ion channel protein. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-11764 RA Aert R., Robben J., Volckaert G., Wood V., Rajandream M.A., Barrell B.G.; RT ; RL Submitted (20-APR-2001) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and Katholieke Universiteit Leuven, Laboratory of RL Gene Technology, Kardinaal Mercierlaan 92, B-3001 Leuven, Belgium XX DR GOA; O13622; O13622. DR GOA; Q9C0W7; Q9C0W7. DR SPTREMBL; O13622; O13622. DR SPTREMBL; Q9C0W6; Q9C0W6. DR SPTREMBL; Q9C0W7; Q9C0W7. DR SPTREMBL; Q9C0W8; Q9C0W8. DR SPTREMBL; Q9C0W9; Q9C0W9. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c691 is overlapped at the 5' end by cosmid c17A3, CC EMBL entry SPBC17A3, accession number AL109652, and at the CC 3' end by cosmid c22H7 XX FH Key Location/Qualifiers FH FT source 1..11764 FT /chromosome="II" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c691" FT /map="IIL" FT misc_feature 1..1508 FT /note="Nominal pverlap with SPBC17A3 AL109652 S.pombe FT chromosome II cosmid c17A3." FT CDS join(383..512,593..643,696..791,853..1009,1071..1232, FT 1282..1624) FT /db_xref="SPTREMBL:Q9C0W9" FT /label=SPBC691.01 FT /note=", len:312, SIMILARITY:Saccharomyces cerevisiae, FT YN66_YEAST, hypothetical 39.2 kd protein in egt2-kre1 FT intergenic region., (336 aa), fasta scores: opt: 271, FT E():2.6e-10, (31.1% identity in 183 aa)" FT /gene="SPBC691.01" FT /gene="pi035" FT /product="hypothetical protein; human reduced expression in FT cancer protein homologue" FT /protein_id="CAC37362.1" FT /translation="MSTNLEEKQRRFSKLQKTLGVVFPAAILLSTGYTVWVFIALICVD FT SNIKIRNGYRNLGGGIVLIIFFFITSGLAYFSYFRVLFSSPSFCGNTLYTYYGFDNPIF FT LCGPNGAPRMCGTCKCWLPDRSHHSRVSMRCIRKFDHYCSFVGKDVCFSNQKFFYQFLF FT YGFSAACMVLISTAIMISRTYHYRSLPGTWIFVLVFSAFGVLFLGVMLVRHTGYLLLNI FT NSHEAKNWKTRIYSFSVFFPEHMDSRVLVQSDPGDLPWDRGYSENWRAVMGDHWYNWIL FT PLRRSPGDGEHFLYSPSFVSKMQSKALSMNS" FT misc_feature 513..518 FT /note="gtacgt, splice donor sequence" FT misc_feature 574..592 FT /note="ctaattatattctatacag, splice branch and acceptor" FT misc_feature 644..649 FT /note="gtaagc, splice donor sequence" FT misc_feature 683..695 FT /note="ctaacctttaaag, splice branch and acceptor" FT misc_feature 792..797 FT /note="gtatgc, splice donor sequence" FT misc_feature 833..852 FT /note="ctaacatcagtttattctag, splice branch and acceptor" FT misc_feature join(891..1009,1071..1128) FT /note="Match to PF01529 zf-DHHC, DHHC zinc finger domain FT Score 58.55" FT misc_feature 1010..1015 FT /note="gtacgt, splice donor sequence" FT misc_feature 1057..1070 FT /note="ctaattttgatcag, splice branch and acceptor" FT misc_feature 1233..1238 FT /note="gtaagt, splice donor sequence" FT misc_feature 1261..1281 FT /note="ctaacaatattatatcaatag, splice branch and acceptor" FT CDS complement(1714..3750) FT /db_xref="SPTREMBL:Q9C0W8" FT /label=SPBC691.02c FT /note="SPACTOKYO_453.01, len:678, SIMILARITY:Lampetra FT reissneri., BAA84733, ephc, (350 aa), fasta scores: opt: FT 114, E():5, (19.5% identity in 287 aa)" FT /gene="SPBC691.02c" FT /gene="pi034" FT /product="hypothetical protein; sequence orphan; low FT similarity to human RAD50-interacting protein" FT /protein_id="CAC37363.1" FT /translation="MMSQQLIDFIDSRTRHPYKSDEVEKFQQEVNELQLPDPNSLPILS FT EEEKRQAREDAAFRRSSEGLEDAWLDSAIPADPTPIFRDTVELLCVYQSFVKKSASLDT FT VANFLDFSTDFSTLSTKKDETEIAPDCLHYIAELLFQKKEREVKEKWKNELTEKLKTLF FT NWPAINPNLKESSKFESFFGFVRSIQSFKDSETGLPLFMQVYITPYVNQFRYHFMSQKQ FT TNVLSKPEWFFEFLLKVFRSNRSFYMLMRDIKFFPGVPPFFTFINLLNNVAKEKLTHII FT KYDDYLVHLVHETLQYSVRLEQHFHYTQDPLIIFLFEQNGTYDKWLGLETQLSLTKLED FT IKIASDAWELESDQSDDFSSAVPTKMTVRFRDMIETTFSVLQNLPSLDYQFNFWRSVQL FT KPMMQYVNWLEAFYESHESSSSIHLPGSLQTDKSKFDIAEVERMCKLYSNFKLLMDWLD FT DIEDEDVYIRIGHKMGSENYAAFYQVKPRLSTLTNGSFRMILRAVSQTLRPLLDNYSDL FT DTWVIKEQLPGAALLSTSVSAEIVGFQSRLKEIIALLQKLLIGSSQCEAIYQIGTLVES FT WMIKIVMTHQFSVRGGVQFAMDAMQIVLEFSDYPLLKFERLMSTVELLSLESGENKLIK FT KLIIEINQKNYDFIDEFFKTKEITLSYEDALGVLYRRVDAWKD" FT CDS complement(4511..7147) FT /db_xref="GOA:Q9C0W7" FT /db_xref="SPTREMBL:Q9C0W7" FT /label=apl3 FT /note="SPACTOKYO_453.02c, len:878, SIMILARITY:Mus musculus, FT ADAC_MOUSE, alpha-adaptin c, (938 aa), fasta scores: opt: FT 1522, E():0, (35.9% identity in 934 aa)" FT /gene="apl3" FT /gene="SPBC691.03c" FT /gene="pi033" FT /product="putative alpha-adaptin" FT /protein_id="CAC37364.1" FT /translation="MVASNNMKGLRAFISDLRSLEHDDEEKRVNVELAKIRAKFQSSTL FT SAYDRKKYVSKLLYIYMLGYPITFGHMEAAKLLSGTKYSEKLIGYLAVALLLNENHELM FT KLVINSIKKDLLSHDSLQNSLALHTIANIGGRELCETVYYDIYKLLMSASNENIVRQKS FT ALALLHIYRKFPDLINPEWFEPIVMILGDDDLNVSLAVSNFVNLIVIREPKYQKFAYGK FT AVGKLKNIVFEHGYSSDYLYYSVPCPWLQVNLCRILLACERPSDNPTRATLIRVLDRIL FT SLPNDNSNVQQVNAVNAILFEAIKLAFLVDESHSLYEKCMDRLADMIADKESNIRYLAF FT ETTAYLISCGHSITSLKHYKELILSSLRYKDVSLRKKSLELLYMMCDEENAKLIVADLL FT QYLPHLDSVTQEDLISKVAIISETFATDYEWYVDVTIQLLRIAGKSADDGVWHQLVHVI FT VNNEEIQEYATKRLFSLLQSETIHECLVKAGGYVLGEFGHLITDYPDSQPVHQFSTIYR FT KLNVSSPSTRVLLLTTLIKLANLQPELNDRIAKVFQEYSTIINPEVQQRACEYLQLLKM FT PRDFLQLVCDEVPPFLDGNRDGVHPKSRPSSKVNLVDTYPQTIPNVSKPSTPIDVPEYD FT ISACLPGFYRLCWKDKGILYQDSQIQIGVRSEYHNSEGAIYLYYENRQSNTLKSLSSTL FT IRTFSTFHLATTFQDTNLPSGVQLQQKYVMSGVNEIFEPPIIHVSYVTGVIRSIDLQLP FT VLLSKFMKPTIFDSYDFFNHWGQMGVEREAQLTFGLNSKDRKLDAKRLTKIVSGFHWGI FT CQNVDSIALNIVGAGIIRFGTQNVGCLLRIEPNYEQNLIRLSIRSTNTSIANTLAKEMQ FT EILRNSF" FT misc_feature complement(5420..7078) FT /note="Match to PF01602 Adaptin_N, Adaptin N terminal FT region Score 471.29" FT CDS 8630..10237 FT /db_xref="GOA:O13622" FT /db_xref="SPTREMBL:O13622" FT /label=SPBC691.04 FT /note="SPACTOKYO_453.03c, len:535, SIMILARITY:Arabidopsis FT thaliana, Q9ZS00, rna helicase., (563 aa), fasta scores: FT opt: 782, E():0, (32.5% identity in 462 aa)" FT /gene="SPBC691.04" FT /gene="pi031" FT /product="putative atp-dependent rna helicase" FT /protein_id="CAC37365.1" FT /translation="MNISLKGAIFSTVGRFNLPKVQGFIRWNSTMKSQQPTLFSEVASL FT SSTFKNSLSRAGFEKMTPVQQRVLNEVFPNEENAVVQAKTGTGKTLAFLLVAFKDVLKG FT KPRLNSSKIHSVILSPTRELALQIFEEARKLTYGTGIRVSYAIGGNSKMREENAIRRGN FT ANLLIATPGRLEDHLQNPRILESLSTDSFILDEADRLMDMGFAESILNIHEAVTTTKTR FT KLCFSATMPPKVSNVFRGILGTDFKLINCLDPNEPPTHERVPQFVIETKLDKVFSSSLS FT LLQQLTSSNPSSRIIVFLPTISMVDFVGGVLENHLKIPCFILHSGLTTAQRRSITESFR FT KCQSGILFATDVVARGMDFPNITQVVQITGPSNTDDYIHRIGRTGRAGKTGEAYLILLE FT QEKPFLNSIKHLPLKRATIEPLSDQALSTLRSDIEKSSKFSRTNALKTLYGSKPHVFSG FT SSQRRATGKNIHESAIALFSLHDVPGLMEELIYKSRGRGSPKGFRGSQLKYPSSSSSSF FT QRRPRSLPSRGRYQQSRR" FT misc_feature 8780..9427 FT /note="Match to PF00270 DEAD, DEAD/DEAH box helicase Score FT 186.94" FT misc_feature 9545..9793 FT /note="Match to PF00271 helicase_C, Helicases conserved FT C-terminal domain Score 86.71" FT misc_feature complement(10595..>11764) FT /note="Nominal overlap p22H7" FT CDS complement(10596..>11764) FT /codon_start=3 FT /db_xref="SPTREMBL:Q9C0W6" FT /label=SPBC691.05c FT /note="SPACTOKYO_453.04, len:668, SIMILARITY:Drosophila FT melanogaster, O97132, abnormal x segregation., (646 aa), FT fasta scores: opt: 308, E():2.5e-12, (24.0% identity in 608 FT aa)" FT /partial FT /gene="SPBC691.05c" FT /gene="pi030" FT /product="putative ion channel protein; by similarity to FT yeast YBR086C" FT /protein_id="CAC37366.1" FT /translation="STIANVPLFLISGCILLFLIAIAFIVDVTLSEVYSGPLKSIVSLL FT PAVVFQVLTLPFTFIYSIVAERLTKLENRRTKTDFQASLSGKMFLQNFMLSYTALFLIS FT YIYGPFAEYFVPHYIQNRMSQSFFSVGYIAKSTFKLNPLRLRNQYIYFLTNAQVINYIT FT ILAVPQLISYVKKHYMSKPTRELHIQDIPSETVTLKRARSEAEKIEYDCYNDYKDFVLM FT FGFLVMFSPIYPLAPIFSLVNCVLYIRSSVYRFTKMVKKPVPCRVDSIAPWDQRLSLLS FT WLGCITMPSICYFYSSTTKPSDKSMVIAAVIGLLSEHLWFLLRMFISSVFPVDKTFFAP FT AKERQHLLAERSFSIPPVADVPTSTTTAFEEADETLSIYRTAENKKTK" XX SQ Sequence 11764 BP; 3779 A; 2096 C; 2079 G; 3810 T; 0 other; aactcaacca cttctactac ttgtcaaaat acacaattat gttcgttggc ttgcgtgaag 60 caattattat tttatatcat tttgaccttt agttatatgt tatttctaaa aaactgtgtt 120 cttcgtacca aaaacttttt acatttttac gcccctttcg tgtactcttc agcttgatag 180 ttctgtaata gacgtaatag cactcgaaaa tttcaaaatc gatatctgcc actaaaatta 240 tttttgtata cttatttatt tatttttttg aaattatctt tataccactt gtattttaac 300 cctcaacagt cgctacgttt ttcttaaaat taaagattcg aaactttctt attcaaatat 360 actaaacgct ttgttggagt tcatgtctac aaatttagaa gagaaacaga ggagattttc 420 taagcttcaa aagactttgg gtgttgtttt cccagctgca attctgcttt caactggcta 480 cacagtttgg gtatttatag ccctaatatg cggtacgtga atgaagggcc aattctaacc 540 gctaagaaag aatttccatt atatagtcat atgctaatta tattctatac agttgattcc 600 aatatcaaga ttcgcaatgg ctaccgaaac ctaggaggag gaagtaagct attaccacag 660 ttaaattaaa acatggacac gactaacctt taaagttgta cttattattt tttttttcat 720 aacttccggg ttggcgtatt tttcatactt cagggttttg ttttcaagtc cttcattttg 780 cggtaatact tgtatgctat tcaataattg agtttgtttt tattgtgttt ggctaacatc 840 agtttattct agtatacacc tattatgggt tcgataatcc aattttttta tgtggaccta 900 atggtgcccc ccgaatgtgt ggaacttgca aatgttggct gcccgatcga tcccatcaca 960 gtagagtcag catgagatgt attagaaaat ttgatcatta ttgttctttg tacgtaaacc 1020 gaaaatcctc tgatctgcat atctttgaat aaagcactaa ttttgatcag cgttggcaaa 1080 gatgtttgtt tttccaacca aaaattcttt taccaatttc tattttatgg attttctgcc 1140 gcctgtatgg ttttgattag tacggcaatc atgatatcga gaacatatca ttatcgtagt 1200 cttccaggga cttggatttt cgttcttgtg ttgtaagttt taccctattc accataacag 1260 ctaacaatat tatatcaata gttccgcctt tggagtttta tttttgggtg taatgttggt 1320 aagacacacg ggatatcttt tattaaatat aaacagccat gaggctaaaa actggaagac 1380 acggatctac tccttcagtg tctttttccc cgagcacatg gactctaggg ttttagttca 1440 aagtgatcca ggtgatttac catgggatcg aggctattct gagaattgga gagcagtaat 1500 gggagatcat tggtataatt ggattttgcc gcttcgtaga tcaccaggtg acggtgagca 1560 ttttttgtat agtccaagtt ttgtcagcaa aatgcaatca aaagctttat caatgaattc 1620 ttaattttta tgatctatta atgtcgttac tatctttgtt ttctagattc tctaaaaaaa 1680 aagaaacatt cgagtcagat aatatttaaa taattaatcc ttccatgcat caactcgccg 1740 atataaaacg ccaagtgcgt cctcgtagga aagcgtaatt tcctttgttt taaaaaattc 1800 atctatgaag tcataatttt tttgattaat ctcgataatt agttttttaa taagcttatt 1860 ttctcccgat tccagagata gtagctcaac agttgacatt aatcgctcga atttcagcaa 1920 aggatagtct gaaaattcta gtacaatctg cattgcatcc attgcaaatt gtacacctcc 1980 tctcacactg aactggtggg tcataacaat ttttatcatc caactttcaa ctaacgttcc 2040 aatctgatat atagcttcgc attgagaaga gccaatcaaa agcttttgga gcagtgcaat 2100 gatttctttt agcctggact gaaatcctac aatttctgca gaaaccgatg ttgataatag 2160 agcagcacca ggaagttgtt ccttaattac ccatgtatca aggtcagaat agttgtcaag 2220 taacggcctt aacgtttgcg aaactgcacg taaaatcatg cgaaaagatc catttgttaa 2280 agtagataat ctaggtttga cttgataaaa agccgcatag ttttctgatc ccattttatg 2340 tcctatacga atgtagacat cctcatcttc aatatcatca agccaatcca tgagtaactt 2400 gaagttactg taaagtttac acatccgttc aacttcagca atatcaaact tggatttgtc 2460 tgtctgcaga ctaccaggta aatgaataga tgatgaactt tcatgagatt cataaaaggc 2520 ttccaaccaa ttaacatact gcatcatagg ctttaactga acagatcgcc aaaaattaaa 2580 ttgataatca agagatggta aattttgaag cacggaaaac gtcgtctcaa tcatgtctcg 2640 aaatcgtaca gtcattttcg tggggaccgc tgagctgaaa tcatcagact gatcgctttc 2700 cagctcccaa gcatctgatg caatttttat atcttccaac tttgtgaggc tcaattgagt 2760 ctctaaaccc aaccatttat cataagttcc gttttgctca aaaagaaaaa taattaaagg 2820 gtcttgggta taatgaaaat gttgctccaa ccgcacagag tattgtaggg tttcgtgaac 2880 taaatgaact aaataatcat catactttat tatatgcgtt aatttttcct ttgcaacgtt 2940 gtttagcaaa ttgataaatg taaaaaatgg agggacgccg ggaaaaaatt ttatatcacg 3000 cataagcatg tagaaactac gattagagcg aaaaactttt agtaagaact caaaaaacca 3060 ttctggtttt gacaatacat ttgtttgctt ctgagacata aagtggtaac gaaactggtt 3120 tacatagggg gtaatgtaca cctgcataaa taatggaaga cctgtttcag aatctttaaa 3180 cgattgaatg gatcggacaa aaccaaaaaa actttcaaat tttgatgatt ccttcaagtt 3240 agggttaata gcaggccaat taaataatgt cttaagtttt tcggtgagct cgttcttcca 3300 tttttctttc acttctcttt cctttttctg aaaaagtaat tcggctatgt aatgtaaaca 3360 atcaggtgca atttctgtct catctttctt cgttgacaat gtcgaaaaat cggtagaaaa 3420 gtctaagaaa tttgcaacag tatcgagaga agccgatttt ttgacaaagg attgatatac 3480 gcataataac tcaactgtgt ctcggaaaat aggcgtcggg tcggcaggta ttgctgaatc 3540 taaccatgcg tcttcaagcc cttcactaga ccttcgaaat gcggcatctt cgcgagcctg 3600 cctcttttct tcttcgctta aaataggaag tgagttagga tccggaagct gaagctcatt 3660 gacttcttgt tgaaatttct ctacttcatc tgacttataa ggatgccgtg ttcttgaatc 3720 aataaaatca attaactgtt gggacatcat caaaaagtcc taggtgaccc ttcaatgaag 3780 tttcagctgc tatttggttc tttgtttact tctctgaaca gttttggaat agtcaatgtg 3840 ttggcacgac tttatttacg gtgctcgcta atgttgctaa tatcatatag tttgaagttt 3900 taaacaataa gactattgca atataaagtg agtagttttt attaaacaaa aattaatatt 3960 caataaattg ttggcttata cttccaaact tgtgattctg agtgggttat atttgacaaa 4020 gatatgctga tggttacact tcgtcgcttt tacgaaaaga agtgaattat acgatataaa 4080 tagcaaaaaa gtgtctcaat tattcaggtc tatattactt ttattaagga cattaagatt 4140 tgttggtatc gactgcgcat atttcgagac agagtattta gatgtttaat gtcctagcgt 4200 gtgccaaata aggaagagtt tttatccatt aaaaacagta taagtatttt cacttagaag 4260 aagttcacta aagcaaatag atataaagaa acaaagataa aataacaaac atcattgaac 4320 agcacttcga atacattaaa attgtattgt actctcgtac ttccaataaa aggggtataa 4380 gttagtatat aaaataaaat tcaaggtaaa tcttcactaa gagatactca actcatcaaa 4440 tgtggacaga ggcataggca ttaaagctat gacaatcaat aaaaattttt gagagtagca 4500 gcgacaacta ttaaaacgaa ttccttaaaa tctcttgcat ttcttttgcc aacgtatttg 4560 ctattgaagt gttagtagaa cgaattgata gacgaatcaa attttgttcg taatttggtt 4620 caatacgaag taaacatcca acattctgtg taccaaatcg aataattcct gctcctacaa 4680 tattaagggc aatagaatca acattttggc atattcccca gtgaaatcca ctaactattt 4740 ttgtcagtcg ttttgcgtca agctttctat ctttgctgtt gagtccgaaa gttaactgtg 4800 cttccctttc cactcccatt tgaccccaat ggttaaagaa atcatagctg tcaaatattg 4860 tcggtttcat aaattttgat aacaaaaccg gtaattggag gtctatcgaa cgtataacac 4920 cagtaacata agacacatga ataatcggag gttcgaatat ctcattaact ccactcataa 4980 catatttttg ctgaagttga actcctgatg gcaaatttgt atcttgaaaa gttgttgcta 5040 aatggaaggt agaaaaggtt ctaattaacg ttgaagagag tgacttcaac gtatttgact 5100 gtcgattttc ataatacaaa tatatggcgc cttctgaatt gtgatattct gaacgaacac 5160 caatttgtat ttgagaatct tggtacaaaa ttcccttatc tttccaacat aaacgataaa 5220 acccaggaag acatgctgat atgtcatatt ctggaacatc aatgggcgtg gatggtttgg 5280 aaacattggg aatggtttga ggataggtat caaccaaatt taccttgctg ctaggacgtg 5340 actttggatg cactccatct cgatttccgt ctaaaaatgg gggaacttca tcacaaacca 5400 attggagaaa gtcccttggc atttttaaaa gttgaagata ttcacatgct ctttgttgta 5460 cttctggatt tataatagta gaatattcct gaaaaacctt cgcaattcta tcgttcaatt 5520 caggctgcaa atttgccagt ttgattaaag tggttaaaag cagaaccctc gtactgggag 5580 aagaaacatt cagcttacga taaattgtag aaaactgatg aacaggttgg ctgtccgggt 5640 aatcggtaat taaatgccca aattcaccaa gaacataacc tccagctttg actaagcatt 5700 catgaatcgt ttcagactgt agtaagctga atagccgttt ggtagcatat tcctggattt 5760 cttcgttgtt cacaatgaca tgaactagct gatgccagac gccatcatca gcggattttc 5820 cagctatccg aagcagttgt atagtaacat cgacatacca ttcatagtcg gtagcaaagg 5880 tctctgaaat tatggcaacc ttagaaataa gatcctcctg agttactgag tcaagatgtg 5940 gtaaatactg caataaatcg gcaacgatga gtttagcatt ttcctcgtca cacatcatat 6000 acaagagttc taaacttttt tttctaaggg aaacatcctt gtacctcaaa gaggataata 6060 ttaattcctt ataatgcttt aaagaagtga tagaatgtcc gcatgaaatt agataggcag 6120 tcgtctcaaa agccaaatac cgaatattgc tttctttatc agcgatcatg tcagcaagtc 6180 tgtccataca tttttcgtac aaagaatgag attcgtcgac tagaaaagcc agtttgatgg 6240 cttcgaaaag gatagcattc accgcattta cttgttgtac gtttgagtta tcatttggca 6300 aactaaggat tcgatctagt acacgtatta gagttgccct tgtgggattg tccgaaggcc 6360 tttcgcaagc aagtagaata cgacaaagat taacctgtag ccaagggcaa ggtacagaat 6420 aatacaaata gtcacttgaa taaccgtgtt caaaaactat gttcttcagt ttaccaaccg 6480 cttttccata agcaaatttt tgatattttg gctcccgaat tacgattaaa ttaacaaaat 6540 tagagaccgc caacgaaacg ttaaggtcat catcacctag tatcataact atcggctcaa 6600 accattctgg gttgattaga tccggaaact ttcgataaat atgtaggaga gctaaggcag 6660 atttctgacg aacaatattt tcgttgcttg ccgacattag aagtttatag atgtcgtagt 6720 acacggtttc acataattct cggccaccaa tgttggctat tgtatgcaag gccaacgaat 6780 tttgtaaaga gtcatgactc aaaagatctt ttttaatact atttataacc aacttcatca 6840 actcatggtt ctcgtttagc aacaaagcaa ctgccaaata accaatgagt ttttcactat 6900 acttcgtccc tgaaaggagt tttgcagctt ccatatggcc aaaagtgatg ggataaccca 6960 gcatatatat atataaaagc ttgctgacat atttttttcg gtcatacgca gataaagtag 7020 aactttgaaa ctttgcacga attttagcca attcaacatt tacacgtttc tcttcatcgt 7080 catgctctaa acttctcaaa tccgagataa acgctcgaag ccctttcata ttgttgctag 7140 ccaccatttt ttactatttg tatactttgt gagcaatcac acttttatcg gtattgtaac 7200 atgcaatatt cttataaact caacccaaaa gattcattac aatggcacta tatccaaata 7260 cccaccaatt gagcttttgg cttagaacaa acaaagttgt aagaagcgac gcgctgttca 7320 aacaatactt tttcgtatta acttcatttt cgttaataga aattatcgta gggggacgta 7380 gcccatgatt ttcaaaacaa cgtactacct agtattactt tatataccaa agtaaacaaa 7440 agattaattt ttagaaaaaa cgtgatgaat gcaaagccgg gtaatggaac tgaatagaaa 7500 atgctttcat ctgtttcata caaacacatg tgcctaaaat attcgacttg ggtttgcgtg 7560 gatgagaaaa ttaatttatg agcatcagta caaaacattt catttagagc agccatccaa 7620 tattgaattt aagcatattt tgctgtgttc ttacttttta cagaaaactc aaaacatttt 7680 ctagcttcaa ggtgtctctc aaacgataaa tctgtattaa atagttagca ggtaagccga 7740 ttccgagtga aatggattaa atcatattat acatgaagcc gtaataattc cggatactga 7800 agggcctttg actttttttc aacaattgga atatcaattg gttttgacaa gtcttatttt 7860 gcttttggag gctaatttct cccattaaag aagcaaaacg aagtatcatt aaattataac 7920 gtgtctaata attttagtct tcacgctttg tttcataaaa acgattttgt ttgcatgggg 7980 caactatgca agcaaaccag ttattttttt tatagacttt gttgtctcaa taatcttttc 8040 tttcaggttg tatcttccca cttttttttc aataaaattg gacttaaaat atggctgaaa 8100 taaaatgaac cagttatttt ataagaattg taacaaaata agatgcattt ggaacttgga 8160 aaaaacaatc aattctttca aattttgaac tactataact aaagcttgaa aacattacag 8220 gaatcgattt atagacataa attgaaggat acaattaaac tcaatacata actactttcc 8280 taaaatattt ttttacatag aattatatat aacaactctt tagctgaaga gttcgtgtta 8340 aaacagctgt caatcttgaa tcgaagaaaa attgaaagtt ggatttccta catgaaatga 8400 cgctttaaac attccttttt tttcataata ttgaggaaat accatattta ctgaagatta 8460 aaattttgta aaattcctct taactttttt ctttggctca tgtatcccta cttccacaac 8520 cattattttt ggaacttttt tttgaactat attgagttac aagtatattt atttcttcgt 8580 aattttgagt caattggtaa tacaagcagt atagttcaga aagtcgagaa tgaatatctc 8640 actgaaagga gctatttttt caactgttgg gagatttaac ttacccaaag ttcaaggatt 8700 tataagatgg aactcgacaa tgaaatcaca gcaaccaacg ctgttttcag aggttgcttc 8760 tctttctagt actttcaaaa atagtttgtc tcgcgcaggg ttcgagaaaa tgactccagt 8820 tcagcagcgg gtattgaatg aagtttttcc taacgaagag aatgctgtag tgcaggcaaa 8880 aacaggtaca ggaaagactt tggctttctt gttagtggcc tttaaagatg tgcttaaggg 8940 aaagccacgt ttgaattcct ccaaaattca ctccgtaatc cttagcccga caagagaatt 9000 ggccttacaa atttttgaag aagctagaaa attgacttat gggacgggaa tccgcgtttc 9060 ttatgccatt ggcggaaact caaagatgag agaggaaaat gcaattcgtc gtggtaatgc 9120 caatcttctg attgcaactc ctgggcgttt ggaagatcac cttcagaatc caaggattct 9180 tgaatcttta tctactgact ctttcatttt ggatgaagct gaccgtttaa tggatatggg 9240 gtttgctgag tcaattttga acattcatga agctgtcaca actactaaga ccaggaagtt 9300 gtgttttagt gcaacaatgc cgccaaaagt ctctaacgtt tttcgtggaa ttcttgggac 9360 tgattttaag ctcataaact gtctggatcc aaacgagcct cctacgcatg agcgtgtgcc 9420 ccaatttgtt atagaaacca agctcgataa ggtattctct tcttctctct cacttttaca 9480 acaactcact tcttcaaatc cctcaagtcg tattatcgtt tttcttccca ccataagcat 9540 ggttgacttt gttggcggag ttttagaaaa tcatttgaag attccttgct ttattttaca 9600 ttccggttta actactgcgc agcgtagatc tattacagaa agctttagga aatgtcaaag 9660 tggtatttta tttgctacag atgttgtcgc acggggaatg gatttcccta acattaccca 9720 ggttgtccaa ataactggtc ctagcaatac cgatgattac attcatcgaa ttggacgtac 9780 gggtagggct ggtaaaacag gagaggcata tttaattctt ctggaacaag agaaaccttt 9840 tttaaatagt atcaaacatt tacctttaaa acgggcaact atcgagccct tatcagatca 9900 agctctctca actttgaggt cggatattga aaagtcatcg aaattttccc gtacaaatgc 9960 tttgaaaact ctgtatgggt ctaaacctca tgtcttctct ggttcgtccc aaagacgagc 10020 caccggtaag aacattcatg aatctgctat tgctttattt tctttacatg acgttcctgg 10080 cttaatggaa gaacttatat acaagtcaag aggtagaggt tcaccaaaag gttttagggg 10140 atctcaatta aaatatccat catcttcatc ttcctccttt caacgacgac ctcgttccct 10200 tccttcaaga ggtcgctatc aacaaagtcg tcgctagttc caccatgaca aaaaaacaaa 10260 acatttcatt tctctgatta ttaaaaatta aaaaaggatg tacattacat gtgatttcac 10320 gcataatact gacgatcgtt atacatttct tttaatactt atggacccgc attttatgaa 10380 ttttttttgt ttggctttct aaagcagaag aagtaaaatg actttttttt atataattat 10440 aagtattaac gcatcttagc atgatatatt taatagttat ttcaatagga atcacaggta 10500 aagatatcct atattccata gtttattgat tatatacatg tgtatcagta aagtaacata 10560 tgttgataaa gtggtaaaat aggtaagagg cgtactcact ttgttttctt gttttcagca 10620 gtgcgataaa tactcaaagt ctcgtctgcc tcttcaaaag ctgttgtagt agatgtcggt 10680 acatctgcaa caggtggtat agagaagctc ctttcagcta ataaatgttg cctttcctta 10740 gctggagcaa agaaagtttt gtcgacgggg aaaaccgaag agataaacat gcgaagcaaa 10800 aaccacaaat gctcagatag aagacctatt acagctgcga tcaccatact tttatcagat 10860 ggttttgtag tagaagaata aaaatagcaa atagagggca tggtgataca acctaaccag 10920 cttagaagag aaagtcgctg atcccaaggt gcaatagaat caacacgaca aggaacgggc 10980 tttttgacca tcttggtaaa cctatagaca gagcttcgaa tataaagtac acaattaact 11040 aaggagaaga taggggcaag aggatatata ggagaaaaca taactagaaa cccaaacatt 11100 agaacaaagt ccttgtaatc attatagcaa tcgtattcaa ttttttcagc ttcagagcga 11160 gctcttttta aagtaacagt ttcagaaggt atatcttgaa tgtgtaattc tcttgtaggc 11220 tttgacatat aatgtttttt gacatatgag attaactgtg gaacagcaag aatggttata 11280 tagttaataa cctgcgcatt ggttaaaaag tatatgtact gatttcttag tctaagagga 11340 ttaagtttaa atgtcgattt agcaatataa ccgacactga agaaagactg ggacattctg 11400 ttttgaatat aatgtggaac aaaatactct gcaaacggtc catagatata agatatcaaa 11460 aatagagcag tatatgaaag cataaaattc tggaggaaca ttttcccgct taaggacgct 11520 tgaaaatctg tcttggtacg acgattctct aatttcgtca acctttcagc aactatagaa 11580 taaatgaaag tgaacggaag agtcaaaact tgaaatacaa ccgctgggag cagggagact 11640 atagatttca atgggcccga ataaacttcc gaaagggtaa cgtcaacgat gaaagctatg 11700 gcaatcaaga aaagcaggat gcatcctgag atcaaaaaca aaggaacgtt ggcgatggtc 11760 gatc 11764 //