ID SPBC651 standard; DNA; FUN; 25350 BP. XX AC AL035570; XX SV AL035570.1 XX DT 26-FEB-1999 (Rel. 59, Created) DT 26-FEB-1999 (Rel. 59, Last updated, Version 1) XX DE S.pombe chromosome II cosmid c651. XX KW cell wall biogenesis cwl1; clathrin coat assembly; KW dna-directed rna polymerase iii; gtp-binding protein; nitrilase; KW TBP binding; transcriptional regulation. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-25350 RA Wood V., Rajandream M.A., Barrell B.G., Volckaert G.; RT ; RL Submitted (25-FEB-1999) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and Katholieke Universiteit Leuven, Laboratory of RL Gene Technology, Kardinaal Mercierlaan 92, B-3001 Leuven, Belgium XX DR GOA; O94659; O94659. DR GOA; O94660; O94660. DR GOA; O94664; O94664. DR GOA; O94666; O94666. DR GOA; O94669; O94669. DR GOA; P53694; P53694. DR SPTREMBL; O94660; O94660. DR SPTREMBL; O94661; O94661. DR SPTREMBL; O94662; O94662. DR SPTREMBL; O94663; O94663. DR SPTREMBL; O94664; O94664. DR SPTREMBL; O94665; O94665. DR SPTREMBL; O94667; O94667. DR SPTREMBL; O94668; O94668. DR SPTREMBL; O94669; O94669. DR SPTREMBL; O94670; O94670. DR SWISS-PROT; O94659; NOG1_SCHPO. DR SWISS-PROT; O94666; RPC1_SCHPO. DR SWISS-PROT; P53694; CWL1_SCHPO. XX CC Notes: XX CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. XX CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. XX CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). XX CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. XX CC The length in codons is given for each CDS. XX CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. XX CC Cosmid c651 is overlapped at the 5' end by cosmid c725, CC EMBL entry SPBC725, accession number AL034352 and at the 3' CC end by c31A8. XX FH Key Location/Qualifiers FH FT source 1..25350 FT /chromosome="II" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c651" FT /map="IIR" FT misc_feature 1..125 FT /note="nominal overlap with SPBC725 S. pombe chromosome 2" FT CDS join(complement(1366..1386),complement(1215..1310), FT complement(1031..1125),complement(1..810)) FT /db_xref="GOA:O94659" FT /db_xref="SWISS-PROT:O94659" FT /label=SPBC651.01c FT /note="SPBC651.01c, len:340, SIMILARITY:Homo sapiens, FT G4191616, gtp-binding protein ngb., (633 aa), fasta scores: FT opt: 1523, E():0, (66.2% identity in 340 aa)" FT /partial FT /gene="SPBC651.01c" FT /product="gtp-binding protein" FT /protein_id="CAB37597.1" FT /translation="MATAVFKNITPIPDVNTFLDVVLSRTQRKTPTVIRSGFKISRIRG FT FYGRKVKFTQDTITEKLDSILQEFPKLNDIHPFHADLLNILYDRDHLKIALSQLSTAKH FT LVENVARDYIRLLKYGDSLYRCKQLKRAALGRMATIIKRQKSSLEFLEQVRQHLSRLPA FT IDPNTRTLLVCGYPNVGKSSFMNKVTRAQVDVQPYAFTTKSLFVGHFDYKYLRWQVIDT FT PGILDHPLEQMNTIEMQSITAMAHLRSAVLYFMDLSEMCGYSVAAQVKLYHSIKPLFAN FT KVTILVLNKIDAMRPEDLDQKNQELLQTIIDDGNVKVVQTSCVQDIGVMDVRTTACEAL FT " FT misc_feature complement(477..500) FT /label=* FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(811..825) FT /note="ctaacaatttcttag, splice branch and acceptor" FT misc_feature complement(1025..1030) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(1126..1141) FT /note="ctaacgaaaatattag, splice branch and acceptor" FT misc_feature complement(1209..1214) FT /note="gtatgt, splice donor sequence" FT misc_feature complement(1311..1325) FT /note="ttaacattgatgcag, splice branch and acceptor" FT misc_feature complement(1360..1365) FT /note="gtattt, splice donor sequence" FT CDS join(2395..2541,2594..2689,2740..3174,3235..3250, FT 3308..3444) FT /db_xref="GOA:O94660" FT /db_xref="SPTREMBL:O94660" FT /label=SPBC651.02 FT /note="SPBC651.02, len:277, SIMILARITY:Mus musculus, FT G3228668, nitrilase 1., (323 aa), fasta scores: opt: 769, FT E():0, (45.4% identity in 282 aa)" FT /gene="SPBC651.02" FT /product="putitive nitrilase homolog" FT /protein_id="CAB37598.1" FT /translation="MTLAAVAQLNSSGSILKNLAICKELISQAAAKGAKCIFFPEASDF FT IAHNSDEAIELTNHPDCSKFIRDVRESATKHSIFVNICVHEPSKVKNKLLNSSLFIEPL FT HGEIISRYSKAHLFDVEIKNGPTLKESNTTLRGEAILPPCKTPLGKVGSAICFDIRFPE FT QAIKLRNMGAHIITYPSAFTEKTGAAHWEVLLRARALDSQCYVIAPAQGGKHNEKRASY FT GHSMIVDPWGTVIAQYSDISSPNGLIFADLDLNLVDHVRTYIPLLRRNDLYPTI" FT misc_feature 2542..2547 FT /note="gtacga, splice donor sequence" FT misc_feature 2574..2593 FT /note="ctaatatctctgacatacag, splice branch and acceptor" FT misc_feature 2690..2695 FT /note="gtacgt, splice donor sequence" FT misc_feature 2719..2739 FT /note="gtaacaaacttgtctttatag, splice branch and acceptor" FT misc_feature 3175..3180 FT /note="gtatgt, splice donor sequence" FT misc_feature 3218..3234 FT /note="ctaattaaaatttttag, splice branch and acceptor" FT misc_feature 3251..3256 FT /note="gtatgt, splice donor sequence" FT misc_feature 3295..3307 FT /note="ctaatgcatctag, splice branch and acceptor" FT CDS complement(4034..5155) FT /db_xref="SPTREMBL:O94661" FT /label=SPBC651.03c FT /note="SPBC651.03c, len:374, SIMILARITY:Caenorhabditis FT elegans., E1350681, y54e2a.12 protein., (430 aa), fasta FT scores: opt: 347, E():6.9e-17, (30.0% identity in 210 aa)" FT /gene="SPBC651.03c" FT /product="hypothetical protein" FT /protein_id="CAB37599.1" FT /translation="MKKKEIKQLKNEIKIALLNSDVETLSHIGKEGHGFLMKSLRKSVW FT VSLCGLSCRHRMECLSRSTSQSSYADQNQVHLDSERSFFQYKLNPFLLRKHRSQLTKLL FT SVVFKHYPELCYYQGLHDIAQILLLTLPFSHALPLMEHLVFYRLRDFMLPTLDGTVKQL FT QLILAVIKARDPTLYEYLIKADIQCYFALSWLITWFAHDVSDISVVCRLFDFFISSHPL FT TVVYTCAQVVLDNRTSIIELLWDNSGADLLHSYLCKLPASINVNQLIKNTCATISAVPF FT SSLPLDRYQISPYSCLRNTGDPWEYMSRSNGLLLFRLQLAELQEEKHKPGTKVPAVFLQ FT ENIFNGCNMLAAITVIGIGIVASQLIPKSTSNS" FT misc_feature complement(4430..5062) FT /note="Pfam match to entry PF00566 TBC, TBC domain" FT CDS 7057..7770 FT /db_xref="SPTREMBL:O94662" FT /label=SPBC651.04 FT /note="SPBC651.04, len:238" FT /gene="SPBC651.04" FT /product="hypothetical protein" FT /protein_id="CAB37600.1" FT /translation="MSSAELGKLHIYASPEQWEKWSPRWKSIVFRTQYESIFKNPKHHG FT EKKPFHCLFKLAGTMKSISLSHLDIPEHRMSNAVAFPITTSTTPMQLDVTLQFRGHKIP FT LVVGEASVSLEDIFTHGTVESVIPLFMKKRHPEAYLRIKLVYTRSKRKSARKHKVPSSF FT HRFSGRRGLGIHYNHSGSQSSLITLPLPQKQPDFLRMNNDTNELKTNGFEPIRFVFTTT FT PYSPASFEVPKTLKT" FT CDS join(complement(8490..9128),complement(8312..8431)) FT /db_xref="SPTREMBL:O94663" FT /label=SPBC651.05c FT /note="SPBC651.05c, len:253, SIMILARITY:Caenorhabditis FT elegans., Q18258, nearly identical to c. elegans predicted FT protein f17c8.5., (365 aa), fasta scores: opt: 475, FT E():2.1e-24, (32.5% identity in 237 aa)" FT /gene="SPBC651.05c" FT /product="hypothetical protein" FT /protein_id="CAB37601.1" FT /translation="MRKRIGIGALNDDEYLKQYEEVGNELIEQQSDEIASQLSTFQEAL FT KTFAREHATEIKQNSQFRNTFVKLALKIGLDPFVSGSDESAWAAVGMNEFYYQVAVRVI FT EVCYATQMENGGLLSVSQVCRFLNEENEAFGHEWLRETDVVRAVDSLAPLGPGFVLEKI FT AGKQYIRSLPLELNTDQNVVLEAVEILGYVTISILRDNYAWERSRCIQVLNDLVSKSLL FT WIDSQGVEMAYWGASNLIDDQAQRFLYENF" FT misc_feature complement(8432..8448) FT /note="ctaaccaaataatttag, splice branch and acceptor" FT misc_feature complement(8484..8489) FT /note="gtacgc, splice donor sequence" FT CDS 9694..10398 FT /db_xref="GOA:O94664" FT /db_xref="SPTREMBL:O94664" FT /label=SPBC651.06 FT /note="SPBC651.06, len:235" FT /gene="SPBC651.06" FT /product="hyptohetical protein" FT /protein_id="CAB37602.1" FT /translation="MPRRAVLFRGNSFISFSSISSGNESSAHGDASLGQADKPLTVDVL FT DAWTTQFTKKQTRVFHEAYVSAYIDLQQKYARLERLQEQILNLERSLLNYKSLKSNSTT FT TVATVPSEKRYFFRRKPKTSSTTNSLSSSSSSVSHMNQDANPNSTVLTFTAVPYDSCLP FT APDRHTPSSASSRASETGTTSPQSMRNQISLLYSKVDQVKTEIASAQAVMHDLLRTYPG FT SESLQQSTHTQF" FT misc_feature 9718..9741 FT /note="PS00030 Eukaryotic putative RNA-binding region RNP-1 FT signature" FT CDS join(10806..10816,10902..11131,11201..11283,11345..11827) FT /db_xref="SPTREMBL:O94665" FT /label=SPBC651.07 FT /note="SPBC651.07, len:266" FT /gene="SPBC651.07" FT /product="hypothetical protein" FT /protein_id="CAB37603.1" FT /translation="MIVIEPTILYEAAALYTRYTANGGDSNDVVALLVGPIVQTLSIPS FT STSSAPLVTSVREILELACNDAVLDKSFLNERLEHCKLQDFPLVGCLVLGNRVDHRVRS FT IAHQLQEATAFPYLMLFPSNFDLTQLKLFRLPDFNNKDQFWKEEWSTEQYEIAENPSGY FT ASALHTLTQLDDGSETNAINVSTQKFAIQKLQSCAMRVREQLEYNPTTFASRDLSSISY FT ICRLLDTMDLPSDTFSHQKSQASFLCALQQILRCTELIEKVYSNGS" FT misc_feature 10817..10822 FT /note="gtacgt, splice donor sequence" FT misc_feature 10886..10901 FT /note="ctaactaaaattgaag, splice branch and acceptor" FT misc_feature 11133..11137 FT /note="gtatga, splice donor sequence" FT misc_feature 11181..11200 FT /note="ctaatccgtaaaccaaatag, splice branch and acceptor" FT misc_feature 11284..11289 FT /note="gtacgg, splice donor sequence" FT misc_feature 11329..11344 FT /note="ttaacgcttatactag, splice branch and acceptor" FT misc_feature 11861..11864 FT /note="true clone end of c31A8 S. pombe chromosome 2" FT CDS join(complement(16537..16560),complement(12293..16486)) FT /db_xref="GOA:O94666" FT /db_xref="SWISS-PROT:O94666" FT /label=SPBC651.08c FT /note="SPBC651.08c, len:1406, SIMILARITY:Homo sapiens, FT RPC1_HUMAN, dna-directed rna polymerase iii largest FT subunit, (1391 aa), fasta scores: opt: 3528, E():0, (51.7% FT identity in 1409 aa)" FT /gene="SPBC651.08c" FT /product="putative dna-directed rna polymerase iii largest FT subunit" FT /protein_id="CAB37604.1" FT /translation="MKDPIDDQIPKRIKHLQFGINGPEEFVKDGTVEVSRRDLYTMTDR FT SPAEHGALDLHMGTSNKQINCATCGESMADCMGHFGYVKLALPVFHIGYFKATLTILQN FT ICKDCSSVLLSDQEKRQFLKDLRRPGIDNLRRSQICKRINDHCKKMRRCSKCDAMQGVV FT KKAGPLKIIHERFRYVRKSQDDEENFRHSFDEALKTIPELKMHLSKAHDDLNPLKVLNL FT FKQITPVDCELLGMDPEHGRPENLLWRYVPAPPVCIRPSVAQEGATTEDDLTVKITEII FT WTSSLIRAALSKGTPISNLMEQWEFMQLSIAMYINSEMPGLRPSDMPSKPIRGFCQRLK FT GKQGRFRGNLSGKRVDFSGRTVISPDPNLRIDQVAVPYRIAKILTFPERVTTQNKKHLQ FT DCIRNGPDVHPGANYVIDRESGFKRFLRFGNRNRIADDLKIGDIVERHLHDNDVVLFNR FT QPSLHKLSIMAHLVKVRPWRTLRFNECVCGPYNADFDGDEMNLHVPQTEEAKTEALELM FT GIKNNLVSPRNGEPIIAATQDFITAAYLLSLKDTFLDRKSISNICCYMMDASTHIDLPP FT PAIIKPRCLWTGKQVFTVLMKPNRFSKVLVNLDAKTRSFSRIKSKTPEMCPKDGYLMIR FT NSEIIAGVVDKSVVGDGKKDSLFYVILRDYGALEAAEAITRLSKMCARFLGNRGFSIGI FT EDVQPGKSLSSQKEILVNKAYATSDDFIMQYAKGILECQPGMDQEATLEAKISSTLSKV FT RDDVGEICMDELGPANSPLIMATCGSKGSKINVSQMVACVGQQIISGKRVPDGFQDRSL FT PHFHKNSKHPLAKGFVSNSFYSGLTPTEFLFHAISGREGLVDTAVKTAETGYMSRRLMK FT SLEDLSSAYDGTVRSSNSDVVQFVYGDDGLDPTYMEGDGQAVEFKRTWIHSVNLNYDRH FT DSAMLPYEIIDYVNRALDDPKFLTNCNRDFIETIRTFVIENIAKYLASVRERRDLAPML FT EEPDMDDLDDMEGDEFAPVAKRKSVENIIRVTEKQLRSFVDRCWEKYMRAKVEPGTAVG FT AIGAQSIGEPGTQMTLKTFHFAGVAAQTTLGVPRIKEIINAAKTISTPIITGQLINDRD FT ERSARVVKGRIEKTYLKDVTSYIEEVYGPVTTYLSIQVNFDTISKLQLDITLADIAAAI FT WNTPKLKIPSQQVTVNNTLQQIHVHTSSDGKSSETEVYYRLQTYKRVLPDVVVAGIPTI FT NRSVINQESGKIELFMEGTGLQAVMNTEGIVGTKTSTNHVMEMKDVLGIEAARYSIISE FT IGYTMAKHGLTVDPRHIMLLGDVMTCKGEVLGITRFGVAKMKDSVLALASFEKTTDHLF FT NAAARFAKDSIEGISECIVLGKLAPIGTNVFQLIRRTEEEEEQKPKELLFDTPSLHQLE FT ITA" FT misc_feature complement(13861..15831) FT /note="Pfam match to entry PF00623 RNA_pol_A, RNA FT polymerase alpha subunit" FT misc_feature complement(16487..16501) FT /note="ctaatattgtggtag, splice branch and acceptor" FT misc_feature complement(16531..16536) FT /note="gtatga, splice donor sequence" FT CDS join(complement(19508..19596),complement(19284..19457), FT complement(17817..19236)) FT /db_xref="SPTREMBL:O94667" FT /label=SPBC651.09c FT /note="SPBC651.09c, len:561, SIMILARITY:Homo sapiens, FT Q92541, myeloblast kiaa0252, (664 aa), fasta scores: opt: FT 639, E():7.8e-28, (27.7% identity in 548 aa), SIMILARITY: FT yeast, RTF1_YEAST RTF1 PROTEIN,(558 aa), fasta scores, FT opt:320, E(): 1.7e-10, (30.3% identity in 485 aa overlap)" FT /gene="SPBC651.09c" FT /product="conserved hypothetical protein; may be involved FT in transcriptional regulation" FT /protein_id="CAB37605.1" FT /translation="MADFQDELLALAGIDDSDVASNRKRAHDDLDDVLSSSSDEDNNEN FT VGQDYAEESGGEGNEKSEDEFEEKFKNPYRLEGKFKDEADRAKIMAMTEIERESILFER FT EEEISKLMERRELAIRLHQQNAQYMAQSTRRSTRDKPLTSAAAGKRDKLTELKKRRQER FT SARSVSERTRKRSPVSDYEEQNESEKSEEEEGYSPSYAEEKVEQVSKDNASANLYDLNA FT IRLGRKHVAEYMYHPIFESTVTGCFVRVKIGERDGQGVYRLCQVKGILESRKPYRVDGV FT LTKVSLECFHGRSKRVFDVNVLSNEPFSDHDFQRWHHQMMEDKLSMPSKNFVQRKLNDL FT RDMSKYVLSEKEVSDIINRKKELSRVPSNIAAEKTRLRQRRQAAYVAGNAELVKEIDDQ FT LNTLEELSMGSNQNSNSAMDQLAKVNERNRRRNHTEIRLAEQRMNEERRRLSAAATATP FT MSAPTSVLTGTSPQPSPSLSTSIMSTPKLNPSESVVVASEKASSPDLSPKLLPSESQIF FT DEGIAVTQTPNTLEDKDFKLHEKAVHGIDDIIATVDFGIDINI" FT misc_feature complement(19237..19250) FT /note="ctaaccaaataaag, splice branch and acceptor" FT misc_feature complement(19278..19283) FT /note="gtacgt, splice donor sequence" FT misc_feature complement(19458..19476) FT /note="ctaacaaaacatattttag, splice branch and acceptor" FT misc_feature complement(19502..19507) FT /note="gtaaga, splice donor sequence" FT CDS 20113..21279 FT /db_xref="SPTREMBL:O94668" FT /label=SPBC651.10 FT /note="SPBC651.10" FT /gene="SPBC651.10" FT /product="hypothetical protein" FT /protein_id="CAB37606.1" FT /translation="MNSALKAIIELCIEEDLLPKSLDVLEYLLSTTSIPIPACYIRMCI FT TLLVHPEYPTSSNIQESCNWILQQVVENRSKINFDAWSFENDLSDNDMPKENYLKIFSN FT QCLFTQDVDYWDLIAYMSSRPPDLERWMSLMDIWLRILEIDAEENGSALMKKYMGEDLC FT ELQDAIRICFSCFTLPQQTMESPFATSMSKAPAKTESRGSNSFEGTSRLANLGAKLLCL FT IWAMLPKGRFFVVHLTDAFHFLSKLDERFSKLNAKQQDLFFGNLGASNLRYCLSQYILM FT KGIGIGINIRHTRCEFTKQLTQLLPTSLPKNKIRQKLHLRAWVSFLGSALRESDRNFDK FT ELFYTTLKQLYTMYQQTELVGIDRPMAILKDMLVLLDISKKLSLDKIV" FT CDS join(complement(22810..22850),complement(22346..22765), FT complement(21481..22297)) FT /db_xref="GOA:O94669" FT /db_xref="SPTREMBL:O94669" FT /label=SPBC651.11c FT /note="SPBC651.11c, len:426, SIMILARITY:Rattus norvegicus, FT A471_RAT, clathrin coat assembly protein ap47 homolog 1, FT (418 aa), fasta scores: opt: 550, E():2.6e-29, (26.8% FT identity in 437 aa)" FT /gene="SPBC651.11c" FT /product="putative clathrin coat assembly protein ap47 FT homolog" FT /protein_id="CAB37607.1" FT /translation="MSTIEAIYLVDTNGALLLQLESRGRTSPITLEHIKNELFRYKLRN FT EEPPFILHNKNFLIFQELEEDVRLCIPTTCDTEPLYIHDIMRRIVDVVKTFFGGFNASK FT VEKNVCVIVQLLAEMIDYGYATCMEPNALQDIVPLPSFMNKFMAVTGLQTNTPTLARDT FT VPWRTAKAKYATNEFFIHVLERVSAVYQPNGKLAFGTVKSDMECKCQISGMPLLLLSLR FT PGTKLGNVRFHQSVNLKRWKQHPDQIEFIPPDGKFTLASFQTDFATQKSLPVVVEAKNK FT LDGRFEVRIRNTGKKSVENLKILITIPQALKSVTVTEGNYIFRASKYTHMEEGILEWSV FT KKLAWTSPALVLTGFLAPLKKDANSTEESSSYSKLEHLDLQYKLQGSTLHNFKVESLKM FT LNHPDKKSYKGVKHTIIAQNVSFRFR" FT misc_feature complement(21579..22832) FT /note="Pfam match to entry PF00928 Adap_comp_sub, Adaptor FT complexes medium subunit family" FT misc_feature complement(22298..22314) FT /note="ctaaccgcatgatttag, splice branch and acceptor" FT misc_feature complement(22340..22345) FT /note="gtatgt, splice donor sequence" FT misc_feature complement(22766..22782) FT /note="ttaatcaagttgactag, splice branch and acceptor" FT misc_feature complement(22804..22809) FT /note="gtatgc, splice donor sequence" FT CDS complement(23229..24050) FT /db_xref="SPTREMBL:O94670" FT /label=SPBC651.12c FT /note="SPBC651.12c, len:274" FT /gene="SPBC651.12c" FT /product="hypothetical protein" FT /protein_id="CAB37608.1" FT /translation="MSSKKVKYNPRKSASQNEATSASAGSKAFGFNSAKKEKLHRMALS FT MEAIEDVEDQSFNGKSSNLVRKRRGLDEDIDEFSSSSEDERKPARHPQSSSQKPFASST FT YNVELPTSPTKITNIGQSSPRALRYLSPESQRIKNAKMKSPISTHLAKYSIHHMGTPPS FT KPSFLSSSVSSPASSKQKSLFQCTKDLEKRYINRVHRSSETELVQLSSIKVLDRFLSDI FT YLVEAEKNEEKCTVLLLKRSNTDVDNSSSLSLTLPLCKFTKNGHQVHIHPC" FT CDS complement(24888..25350) FT /codon_start=2 FT /db_xref="GOA:P53694" FT /db_xref="SWISS-PROT:P53694" FT /label=cwl1 FT /note="SPBC651.13c, len:154" FT /partial FT /gene="cwl1" FT /gene="SPBC651.13c" FT /product="cwl1 protein, putative cell wall biogenesis" FT /protein_id="CAB37609.1" FT /translation="INLPRLFFRTFRYVFLITSIIEFGGLFASNGKRGVLSHFRSSYIT FT CDSKALDRIVNSIVDIFNVMLIQFQRILFAESPILTFTASVAAFIEFFLSGFLSYKSLF FT VWNVLFAFILPRLYVCNERSIKHLVASLERSGDKLKKQATETINTTVNK" XX SQ Sequence 25350 BP; 8154 A; 4826 C; 4435 G; 7935 T; 0 other; aaaagggctt cacaagcggt agtacgtaca tccataacac cgatatcttg aacacagcta 60 gtttgaacca ccttaacatt accgtcgtca atgatggttt gaagaagctc ttgatttttt 120 tgatccaaat cctcaggcct catggcgtca atcttgttga gaaccaaaat agtaaccttg 180 ttggcaaaaa ggggtttaat gctatgatat aatttaacct gtgcagcaac actgtaaccg 240 cacatttccg agagatccat gaaatataaa accgcagatc gaagatgagc cattgcagta 300 atagattgca tttcaatggt gttcatttgc tctaaagggt ggtccagaat accaggagta 360 tcaatcactt gccatctcaa atatttataa tcaaaatgac cgacaaatag agatttagtg 420 gtaaaagcat aaggctgaac atcaacttga gcacgagtaa ccttgttcat gaatgaggat 480 ttaccaacgt tgggatagcc gcaaaccaat aaggttcgtg tatttggatc aattgctggc 540 aaacgagaca agtgctgtct gacttgctca agaaattcga gggatgactt ttgcctttta 600 atgatcgttg ccatgcgtcc caaagcggca cgcttgagct gtttgcagcg gtataagcta 660 tcaccatact tgagcaaacg gatataatca cgagcgacat tttctactaa atgtttggct 720 gtcgagagct gtgaaagagc gattttaagg tgatcgcgat cgtaaagaat gttcaaaagg 780 tcagcatgaa aaggatgaat atcgttaagt ctaagaaatt gttagtgaac catagatagt 840 gatatggaaa taaggaaaga ttcacgatgc tgctgagaat tccaacacaa ttaaacactt 900 aaaaaatcaa taggagtaac acagtgttaa gaatactgtg cacataagaa ttcacaccaa 960 acacgttaaa gcatcatttc tcattcttta acagtgactg caggcatcca tttctttggc 1020 aaatacttac ttagggaatt cctgtaaaat cgaatccagc ttttcagtaa ttgtatcttg 1080 agtaaatttt acttttcgtc cataaaaacc tctaatacga gagatctaat attttcgtta 1140 gtagatgatt cgcaaatcta gaattccaat gcaaccactc taatacgata attgaactga 1200 aaatgtttac ataccttaaa ccctgatcga ataacggtag gtgtttttct ttgagtccga 1260 gaaaggacca cgtccaagaa cgtgttcaca tccggaattg gagtaatatt ctgcatcaat 1320 gttaataaga atgatacaaa ctttcaattt tagaaattaa aataccttga acactgccgt 1380 tgccatggag tagaaaagtt tggtagatgg caaatgtcaa agacaatttt tcaccgttca 1440 cgcagtagtt atccagctag cattgataat ggacgaaggt tcgaatcgta taggtagaac 1500 agtcaccttc tgttaacgaa tttttgtttg acattgataa atcgtataac gcaaagaaac 1560 gcaatagaag gtaaacaaag caagtttata ggcaggcatt atgaatcgaa tatctacggt 1620 ttgtgacaaa ttttattcaa tgttttaatc tacatttcat acttcaaaaa tcccgttatt 1680 ataatcttaa ttttcttttc aagaatattg ggtagtttga tctggtgtcc gaatggatga 1740 aaagtgatag caaaatttca taaaacaaaa tccaagaaat cagtatttat tagaatgcta 1800 cttaaacttt tttcactttc ttaaaatcat gttgtgaaca aaacgattta cattcctaca 1860 ctgcaaatac gaagaataaa atgcatagat tgatttgaac aacagaatgt tgactgaagt 1920 agatgtatgt agattagcag aacttatgtt atagcacttt cattttcttg attctattag 1980 ctttaaagga aatttcgaag ataccctact tgttgatagg ctccatgtat ttaataattt 2040 tgttcgcatt ttatttgaaa aagttagcat ctattttctt tggttctagt atttagttaa 2100 tgacttaaag aatctttctt aggagagcga aatagttcaa ttgaacatac tgtatgccca 2160 tccttcatat tgatgcctaa atcaacatat cgtatagtta cataaagcat aatttatcat 2220 ttttttaaat ttcctttaga cattactttt cacaaatttg cgactttcgc tctatttaac 2280 aaaaatccta tcattttgac agtataatac atcttgtatt gcaatgccag ctttactcaa 2340 cgacaaacta aaccttgtaa acgcagggtc ccattcatcc atttttgtac catcatgaca 2400 ttggcagcag tagctcagct taactcaagt ggttctattc taaaaaactt agccatatgt 2460 aaagaattga taagtcaagc agccgccaaa ggtgcgaaat gcatattctt ccctgaggct 2520 tctgacttta tagctcataa tgtacgacac ttttgcatac tttaccaact ttactaatat 2580 ctctgacata cagagtgatg aggctattga acttacaaat catcctgact gtagcaagtt 2640 tattcgggac gttcgagagt cagctaccaa acattcaatc ttcgtaaacg tacgtactaa 2700 tgtttaacta ctttgatagt aacaaacttg tctttataga tatgcgtgca cgaaccatct 2760 aaggttaaaa acaagctact aaacagtagc ctgtttatcg agcctcttca tggtgaaatc 2820 attagccgtt acagcaaagc tcatcttttt gatgttgaaa ttaaaaatgg accaacttta 2880 aaagagtcga atactacact tcgtggtgaa gctattctcc caccttgtaa aacccctcta 2940 ggcaaagttg gttctgcaat ttgttttgac atccgcttcc cagaacaagc tataaagctt 3000 agaaacatgg gtgctcacat tatcacatac cctagtgctt ttactgaaaa gaccggagct 3060 gctcattggg aagtgctgtt gagagctcgc gctttggact ctcagtgtta tgttatagct 3120 cctgcgcaag gtggaaagca taacgagaag cgtgctagtt atggtcattc catggtatgt 3180 cgtcttcaag tttcacctgt ctgtttaaga attcttgcta attaaaattt ttagattgtt 3240 gacccttggg gtatgtcatt ttgacaattt tattaggtaa aataacttga aattctaatg 3300 catctaggta ctgttattgc tcaatacagt gatatctctt ctccgaatgg cctcattttt 3360 gctgaccttg atttgaatct tgttgaccat gtacgaactt atattccact attacgtaga 3420 aacgatttat acccgaccat ttagcactgt tatacaaact gaggtgattt caatttaaat 3480 taaagagaaa attttttttc ggcttgttta cgaagtattc attattactt acggatttgc 3540 aagattaaag cctgaatact atgaaaataa atttgcgaca attaaataat tccataaaac 3600 cgtaaattac tgagcgctcg atatagtaaa cataatagaa tcgaagtgga atgcaaaaag 3660 taagtactta ttttattaat taatgcataa tttatatatg tataacgatt aggcatcata 3720 taggaaaagt gcaatacaca gacaaaaaga agaaaaatta aaaaaaataa aaagaaatag 3780 acttcttaca ataaagcatg aaaaatcatt aatgactgca ccttcagaat cactttgatt 3840 caaaagtgtt gttttgtgat tagaaaaaaa gttaaaataa aaaacaaaat atagtccctg 3900 cggaaacccc ccgaacattc tttcccatgc gtggaaagaa taaccgtatt atagtagtat 3960 ttggaatata aattaaagga ccctattcaa tttaggatct tgcatgaatt agtaatatta 4020 aacgattaaa atactaagaa ttggatgtgg actttggaat aagttgagat gcgacaatac 4080 cgatgcctat tacagtaatg gccgcaagca tgttgcaacc attgaatatg ttttcttgaa 4140 gaaaaacagc aggaaccttg gtgccaggct tgtgtttttc ttcctgcaat tcagcgagtt 4200 gaagtcgaaa taaaagcaat ccattggatc gagacatata ttcccaagga tcgccagtat 4260 tacgaagaca actgtacgga gaaatttggt atcggtccaa gggtagagaa gaaaagggta 4320 ctgctgatat agttgcacag gtatttttaa ttagttgatt tacgttaata gacgccggaa 4380 gtttgcacaa atagctatgc aataaatcag caccagaatt atcccataaa agctcaataa 4440 tggaagtacg gttatcaagc acaacctgag cacacgtgta cacgacggta agaggatgag 4500 aagagatgaa gaagtcaaat aacctgcata ccaccgaaat gtctgaaaca tcgtgtgcaa 4560 accaagtgat taaccatgaa agagcaaaat aacactggat atctgccttt attaaatact 4620 cataaagagt gggatcgcga gccttgataa ctgctaaaat tagctgcaat tgtttcaccg 4680 tgccatcaag ggtaggaagc ataaagtccc gaagacggta aaatactaga tgctccatta 4740 aagggagagc atgagagaaa ggaagggtaa gaagcaagat ctgggcaata tcatgaagac 4800 cttgatagta gcatagttcc ggataatgct taaagactac actgagcagc ttggtcaatt 4860 gagaacggtg tttacgaagt agaaatggat tcaacttgta ctgaaagaat gatcgttccg 4920 aatccaaatg aacctgattc tggtcggcat aagaagactg agaagtagat ctcgaaagac 4980 actccattcg atgtcgacac gataaaccac aaagactgac ccatacagac ttgcgcagac 5040 tcttcatgag gaagccatgt ccttctttgc caatgtggga aagtgtttcg acatcagagt 5100 tcaataatgc aattttgatt tcatttttta gttgttttat ctccttcttc ttcatctcat 5160 gagcgaaatc gccacttccc ttaagggaga aatatttgaa gaagaatatt tttgaaattt 5220 tgaactgaaa actaaatcac actttgctta ggaatcctga aatcctttaa tctcaggcct 5280 ttactttttc ataaatagct aaatttttct ttaataaaat atctcgtttg gcatctaaaa 5340 caccgtttta taaaggatca aaaaagttgg gcgcagttag tggtctgtgg gttgatgtac 5400 gtacccactt aaatgggaaa aaaaaaatca gaagatgaaa aggaacacaa tgaacaactg 5460 cgccgaacac cctctcgaca accttaataa aagaagatct ttaacaactt taaaaagaaa 5520 gaaagaaagt aaatttaaaa ttttataaaa attcttaaac gaagcatttt tacggttttt 5580 tttttttttt cgaatatcgt tagtattatt actataccat ctccttatga aatttttttt 5640 tgctagttaa tatatgatgg cgaagtaaag tagaagggct tttataaata gctgtaaagt 5700 tcaacagcat gtgtgtcaac tcataaggag agacttccat caaatcaaac aagaagaact 5760 ttctttattt cttctctttt cttcttttct ttttttcaaa ttaaggaaag aatatcagta 5820 tgcactgccg aaatcgttat gttactatta gatggtggat tgtacaaata ataaaattaa 5880 tatccgtatg aatatttgac aaatgaaaca gttccctgct gtagatcctg cgggtttgtt 5940 tagctgtcat tgtaaaacga ttgcggataa atcttcttta ctttcccacc aaataatgct 6000 atatccaaag tatcaaaagt tttgtgcggg taagtcgtta aaataacacc attcctccaa 6060 aaaaataaat aaatataata taaaaaataa aacgaacccc ttcaaacgag ggagaatact 6120 ctcctgaaga tgaacgaatt ttgaaaaatt tttcttattt tttaattaaa atctatttaa 6180 tggtatttgc tgaaaactcg atttgacccc aagcaaatgt tgagacattc atgtaaaaga 6240 aattattacg aaaaagaaaa aaataagcga tgacttaaaa ccatcagtaa tgaatccaca 6300 tgttaaagta gcgaatactt aagcttgata aaaagaatac ctaattctaa tataatccta 6360 gtaggaaata ttaatataaa tttttgaggt ggctctttta ttgaagtatc gcttcatttt 6420 gtattagtta aaataggcaa tacatcaatc tatttagctt ttagattaaa actacatatt 6480 gttatatttc aaaaatccgt gcttaattca gttgggctta ctataatatt aaacagatag 6540 tttctggatt tattttgagt ggaatggctt gtttcagata gaaaggatat gatttgagaa 6600 gtgtgaagtt aagaatttac tgcttttgtc ttaaaaagca tactcaaact tgctgaaaca 6660 tatttaggtc tgtattcatg atgaatctta gttttcccaa tttatttctc atcatctacc 6720 agctaaaccc agcaatctga gtgaaaaggt atcttcatta aaaacctata atcgtgaaaa 6780 tcatattgga atgttctaac atttatcaaa caacatcctt tctgtttaca gcgaggtttc 6840 ttgtgttgat tttgctactt tagataagtc agatcaaggt aacatatttg tgggtcagcg 6900 atctgataac tacagatggc tggtattcga attttcgttt ggattagcaa atttgctgct 6960 tagacctatc tttcctctta ccgcctctcc gtatacattg tacatcccat ctttcatcga 7020 aagcttttga gtatatagac aggcaaagag ctttgaatga gttccgctga actcggaaag 7080 ctacatattt atgcctctcc tgaacaatgg gagaagtgga gtccccgttg gaaaagtatc 7140 gtttttcgaa cgcaatatga atcgattttc aaaaatccga aacaccatgg ggagaaaaaa 7200 ccttttcatt gcctcttcaa actcgctgga actatgaaga gtatctcttt atcgcatttg 7260 gatattccag agcatcgcat gagcaatgca gtagcttttc ctatcactac ttctacaacc 7320 cctatgcaat tagatgtcac cttacaattt cgtgggcaca aaattcctct tgtagtcgga 7380 gaagctagtg tttccttgga agatattttc actcatggaa ctgttgaaag cgtaatacct 7440 ttatttatga aaaaaaggca tcccgaggca tatcttagga tcaaactcgt ttatacgagg 7500 agtaaaagaa agagcgccag gaaacacaaa gttccttctt cctttcatcg attttctggt 7560 cgacgtggtc ttggtataca ttacaaccat tctggttctc agagcagctt aataacttta 7620 cctttacctc aaaagcagcc tgatttttta cgtatgaata acgatactaa tgagctaaaa 7680 acaaatgggt ttgagcctat tcggtttgta tttaccacta ctccttattc acctgcttcc 7740 tttgaggtac caaagaccct taaaacttaa aaaatgattg ttttcttcca aggaatttcc 7800 cttactaatt aattttgttt ccattttcca aggtccatac aactttgcgt cttgctgttt 7860 aatatgacct ccgattctat tctattttat tatattatta ttattcttaa attattgttg 7920 tgttgtttat cactacttcc cgttatttcg agctcttctc ttcttcttct ccttcttata 7980 cctgtacata ttatcttttc cagtttcata ctttatgtct ctcctttttt cggttttcgt 8040 gcttcagttt cttttacttc ttaattcttc taaacccaaa cttttttctc aaacatatat 8100 acatatatat atatattaca tattacgttt tcttcatcga attcaaagtt ttattcttca 8160 ttagtttgac ttttatcaca gcgttactag atgcttttac gaattaatat atagactggc 8220 aaaattaagc gtagggttga ctatctatga acggttgtaa acaagcaggt caacctcccc 8280 caaaattcta ggtagtcttg ataaaaaggc attagaaatt ttcgtataaa aacctttgcg 8340 cctggtcgtc gataagattg cttgcacccc aataggccat ctccaccccc tgggagtcaa 8400 tccagagtaa tgattttgaa actaaatcat tctaaattat ttggttagtc gcaaatgttt 8460 tgagatattt ttataattta actgcgtacc aatacttgaa tgcatctgct acgctcccaa 8520 gcgtaattgt cccgtaaaat agatattgtt acatagccca atatctctac agcctctaaa 8580 acaacatttt ggtcggtgtt gagctctaaa ggaagggacc ggatatactg tttacctgca 8640 attttttcaa gaacaaagcc agggccaagt ggggccaaac tatcgacagc tcgaacaacg 8700 tcagtctctc ttaaccattc atgaccaaag gcttcatttt cttcatttaa aaaacgacaa 8760 acttggctga ccgataagag gcctccattc tccatttgag tagcataaca gacttcgatt 8820 actcgtacag cgacctgata atagaattcg ttcatgccca cggccgccca agctgactca 8880 tcagaaccac taacaaatgg atctaaacca attttcaaag ctaacttaac aaatgtattt 8940 cgaaattgag agttttgttt tatctcagtg gcatgttctc tcgcaaacgt cttcagcgct 9000 tcctgaaacg tcgagagttg agatgcaatt tcatcggact gctgttcaat aagttcattt 9060 cctacttctt catactgttt tagatattca tcgtcgttca aagctccaat tccaattctt 9120 ttacgcatcg gcccaaccga acattgcttg tttcaagcgc acaatcttta tgatcgaggc 9180 ttttaattaa caagtaattt cgaaaaaata tcaacaacaa cgtaattgac cagtttctac 9240 aattattcgc gaataatagt cctcttccaa gatcacagga gttgtgtaga agagcaataa 9300 caacctgctt aggagaataa accatccatt aattataaca atagtaaact aactagctca 9360 tgaaaagaat gtaactaaca ggagcgttac atttcattat ctagtatacc aagttatttc 9420 ctgctatatt agtaaactat cttaaattag aatatcgtat agcagcgcat attcagtttt 9480 ttaacgcact taactggact tccttataaa gttgtttatc acattgttta gctgcggtat 9540 tttcttgatt atagactggt accaccacca atagtgacta agtgtaggcc agagattatt 9600 tggtgctaaa accaactact tcttgggact ctgcgaggct cgagtaattt caatcgtttt 9660 tttttattta ctcacattca gggtgctttg aagatgccaa ggagagctgt acttttccgt 9720 ggcaattcat tcatttcgtt ttcgtcaatt tcctcaggaa acgagagtag cgcccatggg 9780 gatgcttcac ttggacaagc agataaaccc ttaactgtcg acgttttaga tgcttggacc 9840 actcaattca caaaaaagca gaccagggtc tttcatgagg catatgtaag cgcttatatc 9900 gatttgcaac aaaaatacgc tcgacttgaa cgacttcagg agcagatcct taatttggaa 9960 agatcgctgt taaattataa atctttaaaa agtaactcta ccacaacggt ggcgacagtt 10020 ccctccgaaa aacgatattt cttccgccgc aaaccaaaaa cttcttcaac tactaattct 10080 ctctcttctt cttcttctag tgtctcgcat atgaatcaag atgctaaccc caatagcacc 10140 gtattgacct ttactgctgt tccttacgat tcttgtttac ctgcaccaga ccgacacact 10200 ccctctagtg catcgtctag ggcgagtgaa acgggtacca caagcccaca aagtatgagg 10260 aaccaaatta gccttcttta ctcaaaagtc gatcaagtca aaactgaaat tgcttcggca 10320 caagctgtta tgcatgattt gttgcgcact tatcctggca gtgaaagttt gcaacaatct 10380 actcatactc aattttgatg cccctacaca aacaaaaact ctctctattt ttagttttct 10440 gttttatctg cgttttctct tgaaatgaat attttttgtt aagttgtatt ttagagaatt 10500 cgattatcga tggatgtcca ttgatgaatc gatcgaaaga gtcccatgag actttttctt 10560 taattgtttt accctttaat aacttggaag cattcaccaa tatatatttg ttatcgtctt 10620 ttccatcgaa tcttctgtaa ttcacctctt tacctttttc cagcaagcct tgaactttcg 10680 ttacttgggt cgttacttta tactgatgtc ctctaaatta atttcgatcc acttacttcc 10740 ccatctcttt caacatttac actttctgac tatagtaagt gtttaattgt aaaagaggtt 10800 actccatgat tgtaatgtac gttcctcaat aaatgttgct gtacggacat tgccgtaaca 10860 aattcagtca gtcagatata tttttctaac taaaattgaa gtgagccgac aatactttac 10920 gaagctgctg ctttatacac ccgttatact gcaaatggag gcgattctaa cgacgttgtc 10980 gcgttattag taggaccgat cgttcagaca ttatctatac cttcttcaac atctagtgca 11040 ccgcttgtca cttcagttcg ggagattctt gagcttgctt gcaatgatgc tgtgctcgac 11100 aagtcgtttc tcaatgaaag attagaacac tgtatgatca ataagcatca cttcgcttat 11160 gcgcgctaag catcattttg ctaatccgta aaccaaatag gcaaacttca agattttcct 11220 ttagtgggat gtttagtttt gggaaacaga gtggatcata gggttcgttc aattgctcat 11280 caggtacggt acaatgctac ttcgtaacca gttctttgaa ttattttgtt aacgcttata 11340 ctagttacaa gaagctaccg cctttcccta tcttatgctt ttcccatcca attttgactt 11400 gacgcaattg aagttgttcc gtctccccga ttttaataat aaggatcagt tttggaaaga 11460 agaatggtcg acagaacaat atgagattgc tgaaaatcca tctggttatg cttctgctct 11520 tcacacatta actcaattag atgatggaag tgaaaccaac gctattaatg tttcaactca 11580 aaagtttgcc atccaaaaac ttcaatcttg tgcgatgcga gttagagagc aacttgagta 11640 caacccgact acattcgctt caagagattt atcttcaatt tcatatatat gtcgtctgct 11700 cgatactatg gatctaccaa gtgatacatt ctcccatcaa aaatctcaag catcattttt 11760 gtgcgctctt caacagatcc tccgttgcac tgagttaatt gaaaaagtct atagtaatgg 11820 ttcataattt tccttacatt gcatttcgtt tctgccctat gatcatattt aactcaccca 11880 tgtttcttaa tattggcctt aattccaagt tggcatgtct ttaaaacgtc tactttctac 11940 agcacttttc agaattttta aagctataat tattcctctc accatttaca ggtattttta 12000 ctgaaatatt tttatgttcg ttgttcaacg atttaatgct ggaatttttg agacttggtg 12060 taacaaacac ttctttccct tgtataaata attattttat tttcccatta ccaaaaaaag 12120 acgctgggta ttttagacgc ctttgaatat gcaatttaac tattgtagcc aagttgaatt 12180 cgtccgcaat aagatatacg aatcccatca aaactaaatt aaaagttata atataagcct 12240 ttttctcaaa taaaaacata atccaaccga atgtaatata caataaaaat ttttaagccg 12300 taatttccaa ttgatgaaga gatggagtat caaacaatag ttctttcggt ttttgctctt 12360 cttcttcttc tgttcttcta ataagctgaa agacattcgt gccaatagga gccagtttac 12420 cgaggacaat gcattcactt atgccttcga tagaatcttt tgcaaacctc gcagcagcat 12480 taaacaaatg gtccgtagtc ttttcaaacg atgcaagtgc taaaacacta tctttcatct 12540 ttgcgacacc aaacctcgta attcccaaaa cctcaccttt acatgtcatc acatcaccaa 12600 gaagcataat gtgtcgagga tcaactgtaa gaccatgttt ggccatcgta tacccaatct 12660 cagagataat ggagtaacgg gcggcttcaa tacctaggac atccttcatt tccattacat 12720 gattagtact agttttcgtt cccacaatcc cttctgtatt cattacagcc tgtaaaccgg 12780 taccttccat gaagagctca attttaccgg attcttgatt gataaccgaa cgattaatgg 12840 tcggtattcc agcaactaca acatctggta aaacgcgctt atacgtttgc aatctgtaat 12900 aaacttctgt ttcgctactc ttcccatcgg aagaggtgtg aacgtgaatc tgctgaagtg 12960 tgttgttaac agtgacttgt tgagatggaa tcttaagttt tggagtattc caaattgctg 13020 cggcaatatc agctaatgta atatctagct gcaacttcga aatagtatca aaatttactt 13080 gtatagataa gtaagtagtg accggaccat aaacttcctc aatataacta gtaacgtctt 13140 tcaggtatgt cttctcaata cgacctttaa cgacacgtgc agatctttcg tcacgatcat 13200 tgataagctg tccggtgata atgggagtac taattgtttt ggcagcgtta ataatttctt 13260 tgatgcgagg tacacctaga gtagtttggg cagcaacacc agcaaaatgg aaagttttaa 13320 gagtcatctg agtaccaggc tcaccaatgg actgagcacc aatggcacca acagccgtac 13380 caggctctac cttggcacgc atatactttt cccaacaacg gtctacaaat gagcgtagct 13440 gcttctcagt caccctgata atgttctcaa cagattttct tttcgcaacg ggtgcaaatt 13500 catccccttc catgtcatcc aggtcatcca tgtctggttc ttcaagcatg ggggcgaggt 13560 cacgacgctc acgaacagaa gccaaatact ttgcgatatt ttctataaca aatgtacgta 13620 tagtttcaat aaaatctctg ttgcaattgg tcagaaactt tggatcatca agggcccgat 13680 taacataatc tataatttca tatggcaaca tcgcagagtc gtgtctatcg taattcaaat 13740 tgacagagtg gatccacgta cgtttaaatt cgacagcttg accatctccc tccatatacg 13800 ttggatccaa cccatcatca ccataaacaa actgtacaac atcactattt gagcttcgaa 13860 cagtaccatc gtacgcagaa gataaatcct ccaacgattt cattaatcga cgtgacatgt 13920 aaccagtttc ggcggttttg actgcagtat ctacgagacc ttctcgccca gagatagcgt 13980 gaaatagaaa ctcagtaggt gtcaatccac tgtaaaaact attacttaca aatcctttag 14040 ctaacggatg ctttgaattc ttatggaaat gaggaagtga tctatcttgg aaaccatctg 14100 gaacacgttt accactaata atctgttgac cgacacaagc aaccatttga gaaacgttaa 14160 tctttgaacc cttggaacca caggtagcca taatcagagg tgaattagca ggacccaatt 14220 catccataca aatttctccg acatcgtcac gaactttgga aagtgtcgag gaaatttttg 14280 cttcaagcgt ggcctcctga tccattcctg gttggcattc aaggattccc tttgcatact 14340 gcataatgaa atcatcagaa gtagcatagg ctttgttgac caatatttct ttttgagaag 14400 aaagactttt gccaggttga acatcctcaa tacctatgga aaatcctcga ttacctaaaa 14460 atctagcaca cattttggaa agcctagtga ttgcctcggc tgcctctagt gctccataat 14520 cccgcaaaat cacataaaat agtgaatcct tcttgccatc gccaacaact gatttatcaa 14580 caacaccagc tataatttcg ctatttctaa tcattaaata tccatctttg ggacacatct 14640 caggggtctt tgacttaatt cgagagaagg atcgagtttt agcatccaga tttaccaaaa 14700 ctttgctaaa tctattaggt ttcatcaata ctgtaaacac ttgttttcca gtccataaac 14760 agcgaggttt aataatggca ggtggaggta aatcaatatg agtcgaagca tccatcatat 14820 aacaacatat attcgagata cttttacgat ctaaaaacgt atcttttaaa gaaagcaaat 14880 aggcagctgt aatgaaatct tgagttgctg caataatggg ctcaccgttt ctgggactta 14940 caagattgtt tttaatgccc atcaactcca aggcttctgt ctttgcctcc tcagtttgag 15000 gaacatgtaa attcatttca tcgccatcaa aatcggcatt gtagggaccg catacacatt 15060 cattaaatct taaggtacgc catggtcgta cctttaccaa gtgagccatg attgataact 15120 tatggagtga aggttgacga ttgaacaaaa ctacatcgtt atcatgtaga tgacgctcaa 15180 cgatatcacc aattttcaaa tcatcagcaa tacggtttct attgccaaac ctcaaaaagc 15240 gcttaaaccc gctttctcga tctataacat agtttgcacc tggatgcaca tcgggcccat 15300 ttctgatgca atcctgtaag tgcttcttgt tttgagttgt gactctttcg ggaaatgtca 15360 aaattttagc aatgcgatat ggaacggcaa cttgatcaat tcgtaaatta ggatccgggc 15420 taataactgt tctgccggaa aagtctacac gctttcccga caaattacca cgaaatctac 15480 cctgtttacc cttaagacgt tgacaaaacc cccgaatggg ctttgagggc atgtcagaag 15540 gacggagacc tggcatctca ctattaatat acattgcaat ggatagttgc ataaattccc 15600 attgttccat taaattacta ataggagtgc ctttacttaa ggcggcacga attagcgaac 15660 tagtccaaat aatttcagtg atttttacgg ttaaatcatc ttcagtggta gcaccctctt 15720 gggctaccga aggacggatg caaacaggag gagcaggaac gtaacgccaa agtaaatttt 15780 ctggacgacc atgttcagga tccattccca gtagctcaca atcaactgga gtaatttgtt 15840 tgaaaagatt taaaaccttt aaaggattta aatcatcatg ggcttttgag agatgcattt 15900 tcagttcggg tatagttttc aaagcttcat cgaacgagtg tcgaaaattt tcctcgtcat 15960 cttgtgattt gcgaacatac cgaaatcttt cgtgaattat tttcaaagga ccagcctttt 16020 ttaccacacc ttgcattgcg tcgcatttag aacagcggcg catttttttg caatgatcat 16080 taattctctt acatatctgt gaccgacgca gattatcaat gccaggacgt ctcaagtcct 16140 tcaaaaattg gcgtttttct tggtctgata gaagaactga agaacaatcc ttacatatat 16200 tttgtaaaat ggtcaacgta gccttgaagt atcctatgtg aaaaacgggt aaagcaagct 16260 taacataacc aaaatgaccc atacaatcag ccattgattc accacaagta gcacaattaa 16320 tttgcttatt gctggtaccc atatgtaaat ctaaagcacc atgttctgct ggtgatcggt 16380 ctgtcatcgt atacagatct ctcctagaaa cttctacggt tccatcttta acaaattctt 16440 ctggaccatt aattccaaac tgaagatgct ttatcctctt aggaatctac cacaatatta 16500 gtaagtgagt acaaccacaa cacacgaaaa tcatacctga tcatcaatag gatctttcat 16560 tttttaattt gaaaccttga caaaacaaga aatggaagac acaagccaat tcttggcttt 16620 tttctttgcc gtgtcaggat ttggcgaaag gcagctagtt ttctataatg ctcgagtgca 16680 ctgaatactt aaaattaagg gcgttccacc tcgttatata tttcgcatat aatagaattg 16740 tggtttaagc caagagttga ggaggctata tatttagtac attgaagcat gttatgtaca 16800 taattgtcta caaatatcag cccctttgca tttccattct agtgaacttt ggagaaggta 16860 tgaacgcatt cgcatattcc acagaaaatt caattgtaaa tttacaacat aatcaagaga 16920 tacaaattca gtaattctta tttttttaaa gtcacatctg taacttttat gacaattttc 16980 gttaagtcca ccactgctta ggttacgaat tgatgaaaga taaaatgtaa taattattaa 17040 caatgaaatc tataataaac aaaagccaaa tacatttaat caaaaatcgg cattatcggt 17100 atgagaaaat aaaatatgat ggggtaataa atagagtttt aaagcatcat tgataataat 17160 tgtcagcaaa agactgaatt gctgttgttt tataaattcc ttagcaaatg aagaattatt 17220 agtaaaatgg caaaaattgt ttaatcagta ataattgctc ttaattttta tttttttttt 17280 taaaaaaaaa ttagcaatga gctcgagaat taaacatagt tttactgtca actgagtttg 17340 atatcctcca taatttagac atttcaaaaa acaaccctag tccaagggag taatttattt 17400 aatagtaccg gtttcatatt taaaagtttc ataaaattta aaactagaaa aatgacaaaa 17460 aaatgtgaga atggtttctc aactacaatt ttaaaccaaa aattaaggtg tgaaaaaacc 17520 aaaaacaaaa ggaagataaa gatctaataa gaaaaaaagc aaaaaaataa ttataaaaac 17580 gaaacttcat tcaaaatcat tgtcaacatc aagaggaagg caatacggct gcattagaat 17640 ctttcctctg aattaatatt ccactactct aaaccaaagt aacggaaaca gtaaatttta 17700 tgtaggaggg attttcaaaa gctaaacaaa caagaaaaaa gctgacaggt ttatataatc 17760 ctggatgatt tttgcaaact aggataataa taaataaaac gcgagaatac tgagaattaa 17820 atgttgatat caatgccaaa atccacagta gcaataatat catcaattcc gtgaacagct 17880 ttttcgtgaa gtttgaaatc tttgtcctcc aacgtgttcg gggtttgagt cactgcaatg 17940 ccttcgtcaa aaatttggga ttcagaaggt aatagcttag gactcaggtc aggagatgat 18000 gccttttcag aggcaacgac gactgattca ctggggttca gctttggggt agacataatg 18060 gaggtagaaa gggaaggtga aggttgagga cttgttcccg tcagtacgga agtaggtgca 18120 gacattggtg tggcagtagc cgctgctgag aggcgtcttc gttcttcatt catacgctgc 18180 tctgccaggc gaatttcggt atggttgcgg cgtcgattac gttcattcac tttggcaagt 18240 tgatccatgg cagaattact attttggtta gatcccatgg aaagttcttc caaagtgttt 18300 aattgatcgt caatctcctt gaccaattct gcattaccag caacataagc agcttgtctc 18360 ctttgacgaa gacgggtctt ttcagcagcg atgttcgaag gaacacgcga taactctttc 18420 ttcctgttaa taatatcaga aacctccttt tcgcttaaaa cgtatttact catatccctg 18480 aggtcattca gctttcgttg tacaaaattt ttagagggca tggaaagctt atcttccatc 18540 atttggtgat gccatcgttg gaaatcatgg tcggaaaaag gctcatttga taagacgttg 18600 acatcgaaca ctcttttcga gcgaccatga aaacattcca gtgaaacttt agttaaaaca 18660 ccatcaacac gatacggctt tctgctttct aaaataccct tgacttgaca taagcgatat 18720 acaccttgtc catcacgctc accaatttta acccgaacaa agcatccagt gacggtggac 18780 tcaaagatag gatgatacat gtactccgcg acatgtttac gcccaagacg aattgcattt 18840 aaatcgtaca aattggcgga tgcattatct tttgaaactt gttcaacttt ttcctcagca 18900 tagctgggag agtaaccttc ctcttcttcg ctcttctccg actcattctg ttcttcataa 18960 tcggaaacag ggctcctttt tctagttctt tcagagacgc ttctagctga acgttcctgg 19020 cggcgctttt tcagctcagt aagcttatca cgtttgccag cggctgctga agttaaaggc 19080 ttgtcacgag tagaccttct agtagattgc gccatatact gagcattttg ctgatggagg 19140 cgaattgcca attcacgcct ttccatcaac tttgaaattt cttcttcacg ttcgaagaga 19200 atactctctc tctcaatttc cgtcattgcc attatccttt atttggttag acaactttat 19260 gaaaaatgta aaaatcaacg tactttgctc tgtctgcttc atctttaaac ttgccctcta 19320 gacgatacgg gtttttgaat ttttcttcaa attcgtcttc cgacttctca tttccttctc 19380 ctccagactc ttccgcataa tcctgtccaa cattttcatt attgtcttcg tctgaactgc 19440 tgctcaacac atcatctcta aaatatgttt tgttagcaag gtcaatccga taaatttgct 19500 ttcttacaaa tcatcatgag cccttttacg gtttgaagca acatctgagt catcaatacc 19560 agctaatgcc aacaattcat cctgaaagtc ggccatcttg gtggaggaca ggatcagatt 19620 agctagatac ctgactaata acggttccaa ggactctcca ccaatttcat aacagcagcg 19680 aaacttttat ctactagctt tcaaaggtac tatctgctag tacattaaaa gaataatgtt 19740 tttataattt gaaaagtgat ttttttttta attttttttt tacgaaataa tttttgcaga 19800 tgttgtcttc cttggttaca aaccttatcg ttgaaagctt ccttttaaaa tactgctcat 19860 ttggggtcct cctctttccc tctttttgaa tatatttctt ctgtcgcgta aaaacttcaa 19920 actgagaatt ctgcattttg ttacaatata aaattcgtga atcaaaccat tcaataataa 19980 tcacaagact gtaaataggg cacatgttaa atgctctttt acaaagaaaa tcgttttaag 20040 aaataagata tctcttccat atctggcttc ttttacatat aaagtagcaa agattgctta 20100 cgccatttca aaatgaactc ggctctaaag gcaataatag agctttgtat tgaagaagac 20160 ttgttgccaa aatcattaga tgttttagaa tatcttctat cgacgacctc tataccaatt 20220 ccagcttgtt atatacgaat gtgcataact cttctagtcc acccagaata tcctacctct 20280 tctaatattc aagaaagctg taattggata ttacagcagg tggttgagaa cagaagcaaa 20340 atcaactttg acgcatggtc atttgaaaat gatctatcgg acaacgatat gcctaaagaa 20400 aattatctga agattttctc caaccaatgc ttatttaccc aagatgttga ttattgggat 20460 ctaattgcat acatgtcttc tcgtcctcct gaccttgaac gttggatgtc cttgatggac 20520 atatggttaa ggatattaga gatcgatgct gaggaaaacg gatctgcgtt gatgaaaaaa 20580 tacatgggag aagatttgtg tgaacttcaa gatgccatca gaatttgctt ctcctgtttc 20640 actcttcccc agcaaacaat ggaatcacct tttgcaacaa gtatgtccaa agcacctgct 20700 aaaacagaaa gtcgaggttc aaatagtttt gaaggaacat caagactagc aaacctaggt 20760 gccaaactct tatgccttat atgggctatg cttccgaagg gaagattttt tgttgtacat 20820 ctgacagacg cttttcattt tcttagcaaa ctcgacgaac gtttttcaaa actgaatgcg 20880 aaacaacaag atcttttctt tggaaactta ggcgcctcca atctccggta ttgcctgagc 20940 caatatatac ttatgaaagg aataggtatt ggaattaaca tacgccatac acgttgtgag 21000 tttactaaac agctaactca acttttaccc acttcccttc cgaaaaacaa aatcagacag 21060 aagctacatc tacgagcatg ggtctcattt ttgggttcgg cccttcgtga aagtgatcgc 21120 aactttgata aagagctatt ttacacaacg ttgaagcagt tatacacaat gtatcaacaa 21180 acagaattag ttggtattga tagaccaatg gcaatactca aagacatgct tgtattatta 21240 gatatttcaa aaaaattgtc cttggataaa atcgtttaac ttaataattt aactacaaat 21300 taacagaagt catttggcat taattgtgta tcctaatata tatagactat atgtatcgtt 21360 tcaatgaatg aggctttgtg tggaaaataa ttattataat cattagtgat aactaagaaa 21420 atgaaattta tatgaataat atataataaa caaacgggta gatagaaagt aaattaatta 21480 ttaccgaaaa cgaaatgaaa cattttgtgc aataattgta tgcttgaccc ctttataaga 21540 ttttttatct ggatgattaa gcatcttcaa tgactctact ttaaaattat gaagggttga 21600 tccttgaagt ttatattgta aatcaaggtg ctcaagctta gagtagctac ttgactcttc 21660 ggttgaattg gcatctttct ttaagggggc caggaatcct gtcaacacta aggccgggga 21720 tgtccaagct aattttttta ccgaccactc cagaatacct tcttccatat gagtatactt 21780 ggaagcacga aaaatataat ttccctcggt aaccgtaacg ctctttagag cttgaggaat 21840 agttattagg atttttaaat tttcaacgga ttttttcccg gtgtttcgaa tacgtacttc 21900 gaaccttcca tccaacttat tttttgcttc aacaacaaca ggcaaagatt tctgggtagc 21960 aaagtctgtt tgaaaagaag ctaatgtaaa ttttccgtcc ggtggaatga attcaatctg 22020 atccggatgt tgtttccatc tttttaaatt gactgactgg tggaaccgaa cattccctag 22080 ttttgtgccg ggtctcaaac tcagcaaaag taaaggcata ccagatattt gacatttgca 22140 ttccatatca cttttaactg tgccaaaagc aagttttccg ttaggctggt aaacggctga 22200 tacgcgttca agtacatgaa taaaaaattc attggttgca tattttgctt tagctgttct 22260 ccaaggaacg gtatctcttg caagagtcgg tgtatttcta aatcatgcgg ttagcactgc 22320 aaaaacagaa aactaaataa catacgtttg tagaccagta actgccataa acttattcat 22380 aaagctaggg agtggtacaa tgtcctgcaa tgcatttggt tccatacaag ttgcatatcc 22440 ataatcaatc atttcagcta atagctggac aataacgcaa acatttttct cgacctttga 22500 agcattaaac ccaccaaaaa atgttttaac tacatccaca atgcgtctca taatatcatg 22560 aatgtagaga ggctcagtgt cgcaagttgt aggaatacac aaacgcacat cttcctctaa 22620 ctcttgaaat atcaaaaaat ttttgttatg taatataaat ggaggctcct catttcgaag 22680 tttgtagcga aaaagttcgt tttttatatg ttctaacgtt atgggagatg tccttcctcg 22740 agactccaac tggagtagta acgccctagt caacttgatt aataaagtaa ataaacagct 22800 aacgcatacc cattagtgtc tacaagatat attgcttcta ttgtgctcat tcaaaagttt 22860 tatgaaagga gcggttggtt ggtgatgaat acgtatgaag gtaaatggat taagaaggtc 22920 ttctagtgta caggaaaggg taaccataga tgtcctttct caatcttttt aaagcctaat 22980 ttataaacaa tttaagtaat taatagtaat taagccatgc tactgttgac atgctaaacc 23040 gtttaaatgg gttgctaaaa ggtacgcagg aacctcaggt tgaaaaatta attagattaa 23100 acagaaaacc acctttcata aatgtcgtag attaagatac ttgtaaaaaa tatatatata 23160 tgacaaataa atatatcaca atgaacttta cgctttgtgt aaatatagca aaaagcatta 23220 tatatgaatc agcaaggatg tatgtgtact tgatgcccat ttttggtaaa tttacacaaa 23280 ggtaaagtaa gagatagaga gctactattg tctacatcag tattagaacg ttttagaagt 23340 aaaactgtgc atttttcctc atttttttca gcttcaacta gatatatgtc agagagaaat 23400 cgatcgagaa ctttaatgga agaaagttgc acaagctcag tttcagatga acgatgaaca 23460 cgattgatat atctcttctc gagatctttt gtgcactgga aaagtgattt ttgtttacta 23520 gatgcagggg aagacacgct agaactcaag aatgacggtt tagatggtgg agtacccatg 23580 tgatgaatag aatatttagc cagatgtgtt gaaataggcg acttcatctt ggcgtttttt 23640 attctctgag attctggaga caggtagcgc aatgctctag ggcttgactg accgatattg 23700 gtaattttag tcggagatgt tggaagctct acgttgtatg tagagctagc aaatggtttt 23760 tgagaggagc tttgaggatg tcgagcaggc tttctttcat cctctgatga agaagaaaat 23820 tcatcaatgt cttcatccaa accccgacgc tttctgacta gattggaaga cttgccattg 23880 aacgattgat cctcaacatc ttcaattgct tccatagaca gcgccattct atgaagtttc 23940 tcctttttcg cggaattaaa tccaaaagct ttgctacctg ctgaagctga ggtagcttca 24000 ttttgagatg cgctttttcg aggattgtat ttgactttct tggaactcat gtataatagc 24060 gttgcggcat gataaattga caataaattg aatttcaata atcctaatat atggatacaa 24120 aggaaatttt gagcttaaac gtaaaaagct ggcacaacat tgatataagt gaatgacttg 24180 tggtgagagc agacaacgat catgcgagtg taatcagcac tttactgtat gatcggctgt 24240 attaaatacg aagtagtgga aaaaaaataa taatttttgg ttaacaaata ctttagtcat 24300 ttggttaaac aaaatagatt ttttcgtcca cagacccatt ttagttatgg aaaatatata 24360 tatatatttt ttttttcgaa aagagcagca ataaggaata cgaggaggac ctacaaaaca 24420 acacggagta attacgagat taaattacga ataataagta cgttgggtat taaacgaagc 24480 agagaaaata taataaaata gcatcatatt gagcaaagca acaagaactt caaccacact 24540 gcaatagttt gcaactcaga agagaaatga gagattgagc cgaacctgtt acatttacaa 24600 tatatcgaga tgagaaagac gtatttatga aaataaacac tcatagtcat aagcaaaata 24660 attgagaaaa cgcattcaat ctcctaattc aagtcataat acaacacttt tgaaacgcaa 24720 cacaacacag caacacattt tcaaagttga aaacaaaacc atggttatta cccttgcatt 24780 tttttgcaaa agatactatt gaaaccttaa aataaacgag gaagcgaacc aaataaaaat 24840 caagcgcaac ctgacagaaa caatcaaaca aattatcccg cagaggttta cttgttaaca 24900 gtggtgttta tagtctcagt agcttgcttt ttaagtttat caccagatct ctcaagggaa 24960 gcaaccaaat gcttgataga gcgctcattg catacataca atctgggaag gatgaaggca 25020 aacaaaacat tccaaacaaa gagagacttg taggaaagga agccactaag gaaaaactca 25080 ataaaagcag caacagaggc agtaaaggtc aaaatagggc tctcagcaaa caagatacgt 25140 tggaattgaa tcaacataac gttgaaaatg tcgacaattg agttgacaat cctatcaaga 25200 gccttggagt cgcaggtgat gtaggaggaa cggaagtgag acaagacacc acgcttaccg 25260 ttggaagcga aaagaccacc gaattcaatg atggaggtaa tcaaaaagac ataacggaaa 25320 gttctgaaaa agaggcgagg aagattgatc 25350 //