ID SPBC649 standard; DNA; FUN; 11999 BP. XX AC AL023587; XX SV AL023587.2 XX DT 16-MAY-1998 (Rel. 55, Created) DT 28-NOV-1999 (Rel. 61, Last updated, Version 3) XX DE S.pombe chromosome II cosmid c649. XX KW 40s ribosomal protein; DNA repair; GTP-binding; gtp1; kinesin-like protein. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-11999 RA Purnelle B., Goffeau A., Lyne M., Wood V., Rajandream M.A., Barrell B.G.; RT ; RL Submitted (12-MAY-1998) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and Unite de Biochimie Physiologique, Universite RL Catholique de Louvain, Place Croix du Sud 2/20, B-1348 Louvain-la-Neuve, RL Belgium XX DR GOA; O59751; O59751. DR GOA; O59753; O59753. DR GOA; O59755; O59755. DR GOA; P32235; P32235. DR GOA; P40388; P40388. DR GOA; P79016; P79016. DR SPTREMBL; O59753; O59753. DR SWISS-PROT; O59751; KLP6_SCHPO. DR SWISS-PROT; O59755; CU12_SCHPO. DR SWISS-PROT; P32235; GTP1_SCHPO. DR SWISS-PROT; P40388; UV15_SCHPO. DR SWISS-PROT; P79016; R19B_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c649 is overlapped at the 3' end by c354 and at the 5' end CC by c1685. XX FH Key Location/Qualifiers FH FT source 1..11999 FT /chromosome="II" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c649" FT /map="IIL" FT misc_feature complement(1..989) FT /note="nominal overlap with cosmid SPBC1685, EM:AL031154 FT S.pombe chromosome 2" FT CDS join(complement(2388..2418),complement(24..2347)) FT /db_xref="GOA:O59751" FT /db_xref="SWISS-PROT:O59751" FT /label=SPBC649.01c FT /note="SPBC649.01c, len:784, SIMILARITY:Schizosaccharomyces FT pombe, YB3D_SCHPO, putative kinesin-like protein c2f12.13., FT (883 aa), fasta scores: opt: 1463, E():0, (43.9% identity FT in 805 aa)" FT /gene="SPBC649.01c" FT /gene="SPBC1685.15c" FT /product="kinesin-like protein" FT /protein_id="CAA19043.1" FT /translation="MKEGSSISVAVRVRPFTEREKGLLAETPKSKEFLGDGSLAVSNTS FT SNTFCTNGIRKIVRVLDDNVLIFDPPEENPLAKVQKSLLPAGKRFRDVRYAFDRLFGEE FT ASQEDVYKGTTEPLLDSVLQGYNATVFAYGATGCGKTHTISGRPDDPGIIFLTMRALLD FT RVEGLKRTMNVDISVSYLEIYNEKIRDLLVQDPLSMEKPKSLNICEDAEQNVSVPGLSY FT FTPTNLEEVMEIIIRGNSNRTMSPTEANAVSSRSHAVLQIYITQTPKSGEKQEESESQN FT SHKVRSVFSFIDLAGSERASATKNRGKRLVEGANINRSLLALGNCINSLCEPRRRQHVP FT YRDSKLTRLLKFSLGGNCRTCMIVCISPSSEHYDETHNTLKYGNRAKNIKTKVSRNVVS FT VDRHVSEYVRTIYELRQKVSILQKRIAEESKQLALNKEVRKISSREIKMLDARSMLKNS FT FDGSRDLQKSLIEHVRTLRRIEDEITLTKMWISIAKESDAMSGHNIKSVETRLAKLYDQ FT RSLITAKVNPEEICKTFQNSISHIVSSFKGEGADMYADMLQDDVDLLKSIIENQILDAK FT HESETFSSTSRKLIQNLFLLFPLLPGNAIDVNESLARAFDQLVGIVPSEPTIQVPNLIE FT KGKAPLLSMFEIPRSPSRFKARSPSKAARVLKKPLKKRVRFSEVPTTSSVPPVEIKNKD FT SKPKVEKSLDKHNMNNDRSFLVPSRDARNSLTSLSLHSNVAKNKSSHSSKWPTHTLSPI FT ITTALKQPVRRISLVSQPLQKTGGTENTPNA" FT misc_feature complement(1128..2099) FT /note="Match to PF00225 kinesin, Kinesin motor domain Score FT 359.55" FT misc_feature complement(1485..1520) FT /note="PS00411 Kinesin motor domain signature" FT misc_feature complement(2348..2359) FT /note="ctgaccatcaag, splice branch and acceptor" FT misc_feature complement(2382..2387) FT /note="gtaaga, splice donor sequence" FT CDS join(2710..2785,2959..3314) FT /db_xref="GOA:P79016" FT /db_xref="SWISS-PROT:P79016" FT /label=rps19 FT /note="SPBC649.02, len:143" FT /gene="SPBC649.02" FT /gene="rps19" FT /product="40s ribosomal protein s19" FT /protein_id="CAA19044.1" FT /translation="MAGVSVKDVDAQQFINAYAAFLKRSGKMTTPQWIDIVKTGTHKEL FT APYDPDWYYVRAAAIARHIYLRKQVGVGRLCKVYGGSVNRGMRPSHHRDGSGSVQRKVV FT QSLEKIGVLEKSDNGGRRISQQGQRDLDRIAYSLLEDEE" FT misc_feature join(2719..2785,2959..3311) FT /note="Match to PF01090 Ribosomal_S19e, Ribosomal protein FT S19e Score 297.30" FT misc_feature 2786..2791 FT /note="gtaggt, splice donor sequence" FT intron 2786..2958 FT /note="confirmed intron" FT misc_feature 2944..2958 FT /note="ctaactgatccgtag, splice branch and acceptor" FT misc_feature 3147..3206 FT /note="PS00628 Ribosomal protein S19e signature" FT CDS 4312..5181 FT /db_xref="GOA:O59753" FT /db_xref="SPTREMBL:O59753" FT /label=SPBC649.03 FT /note="SPBC649.03, len:289, SIMILARITY:Saccharomyces FT cerevisiae, RA14_YEAST, dna repair protein rad14., (371 FT aa), fasta scores: opt: 574, E():8.5e-28, (39.9% identity FT in 283 aa)" FT /gene="SPBC649.03" FT /product="putative dna repair protein with XPA domain; FT yeast rad14 homolog" FT /protein_id="CAA19045.1" FT /translation="MENSSIVKSPNPTIEEQRNEIEKLKNLTGIEEVHVDGAKVNKRKR FT TFDEQSEITKDYIEYDFSKIEDTKGGYLLEEKKVEDLREKPAERELREQEERQKKLRLA FT PLNLDPETAPKCFECDSIELDTKYFDIFHCRVCHTCREKYPDKYSLLTKTECKLDYLLT FT EPELQDQELLPRLLKANPHQQGWSNMMLYLRYQVEEFAKKKWGSMEALDAEFERREVQK FT KEMKEKKFEKQLLELRKRTRTSNYSRMSIREKRKHVHSYDEEFEKPNEPGVIVQRCKCG FT LEIEQLEI" FT misc_feature 4315..5178 FT /note="Match to PF01286 XPA, XPA protein Score 171.07" FT CDS join(6745..6780,6850..7031,7242..7287) FT /db_xref="GOA:P40388" FT /db_xref="SWISS-PROT:P40388" FT /label=uvi15 FT /note="SPBC649.04, len:87" FT /gene="uvi15" FT /product="UV induced protein" FT /protein_id="CAA19046.1" FT /translation="MSAQQFYGDKGYAPAPPQQAYGGPNYYPPQQNYPQQGYAPPQGYP FT QGGYPAQQPMYVQQPQASDPGGDLCCGLLTGLACCCCLDAMF" FT misc_feature 6781..6786 FT /note="gtatgg, splice donor sequence" FT intron 6781..6849 FT /note="confirmed by mRNA" FT misc_feature 6831..6849 FT /note="ctaacagcttcaattttag, splice branch and acceptor" FT misc_feature 7032..7037 FT /note="gtaagt, splice donor sequence" FT intron 7032..7241 FT /note="confirmed intron" FT misc_feature 7225..7241 FT /note="ctaacgactgtttttag, splice branch and acceptor" FT CDS join(8610..8616,8659..10298) FT /db_xref="GOA:O59755" FT /db_xref="SWISS-PROT:O59755" FT /label=cut12 FT /note="SPBC649.05, len:548" FT /gene="SPBC649.05" FT /gene="cut12" FT /product="spindle pole body component cut12" FT /protein_id="CAA19047.1" FT /translation="MSETLNTPPTYAWVLKAFSSKLAGTVTKPVTKMSSYIEDAESDAE FT LPQDAKEDLRPTETLTPLKSKAAQNGILKTPGTLQIKKTVNFKDISKDAATWNRPTKNN FT FLFTRLDDENPLMGHEEFKSPLLQSTPKPNINNPDNENKSKHDEFDNRYNININESYKN FT ETKSNQRLGEDVPSKKKYPHSMDAEISKFKWDSNNNNDWSSLMKDCFRDVVNNNRKMKE FT IIKDVMIDTSQAFPSESLDEPDYTINLDAPRSSSGKYWKQKFSMLDSAHSDLELELTSI FT RERLESLILEKQEEINFWKQRCRALETEKIHNHQGQQSKYKGKEFVGNRFSQMRELYTA FT KPSPITTKVVSRPSQSDVREPQEQVPSKNLHRGADMSHLAAQMLTHSSKKSHTTNLIPS FT EGIISSTPISAASKVRMNLMQSNQTPTPAPFSIAAKKSHLPSKLSFPQDGGSLSSATTL FT QQLPKARVTPNVLSSLSSNLGKTNPTSVYQSKANVTTSADVEKPQVKVATSSRVDYDLK FT SPNQRTANAKKRLEERRRRRKLKLQELQLNS" FT misc_feature 8617..8622 FT /note="gtaagg, splice donor sequence" FT misc_feature 8642..8658 FT /note="ctaatctcaaaatttag, splice branch and acceptor" FT CDS join(10748..10765,10811..10879,10995..11165,11219..11999) FT /db_xref="GOA:P32235" FT /db_xref="SWISS-PROT:P32235" FT /label=gtp1 FT /note="SPBC649.06," FT /partial FT /gene="gtp1" FT /gene="SPBC649.06" FT /gene="SPBC354.01" FT /product="gtp-binding protein 1." FT /protein_id="CAA19048.2" FT /translation="MGVLEKIQEIEAEMRRTQKNKATEYHLGLLKGKLAKLRAQLLEPT FT SKSGPKGEGFDVLKSGDARVAFIGFPSVGKSTLLSAITKTKSATASYEFTTLTAIPGVL FT EYDGAEIQMLDLPGIIEGASQGRGGRQAVSAARTADLILMVLDATKAADQREKIEYELE FT QVGIRLNRQPPNVTLTIKKNGGIKFNHTVPLTHMDYKMAYNILHEYRIHNADILIREDI FT TVDDFIDLVMGNRRYINCLYCYSKIDAVSLEEVDRLARLPKSVVISCNMKLNLDFLKER FT IWEELNLYRIYTKRKGEMPDFSEALIVRKGSTIEQVCNRIHRTLAEQLKYALVWGTSAK FT HSPQVV" FT misc_feature 10766..10771 FT /note="gtaaat, splice donor sequence" FT intron 10766..10810 FT /note="confirmed intron" FT misc_feature 10793..10810 FT /note="ctaatctaaattggctag, splice branch and acceptor" FT misc_feature join(10811..10879,10995..11165,11219..11998) FT /note="Match to PF01018 GTP1_OBG, GTP1/OBG family Score FT 542.34" FT misc_feature 10880..10885 FT /note="gtaagt, splice donor sequence" FT intron 10880..10994 FT /note="confirmed intron" FT misc_feature 10978..10994 FT /note="ctaacctagtcctttag, splice branch and acceptor" FT misc_feature 11112..11135 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 11166..11171 FT /note="gtttgc, splice donor sequence" FT intron 11166..11218 FT /note="confirmed intron" FT misc_feature 11201..11218 FT /note="ctaacaatggtaatatag, splice branch and acceptor" FT misc_feature 11303..11344 FT /note="PS00905 GTP1/OBG family signature" FT misc_feature 11645..11999 FT /note="nominal overlap with cosmid SPBC354, EM:AL022071 FT S.pombe chromosome 2" XX SQ Sequence 11999 BP; 3791 A; 2123 C; 2218 G; 3867 T; 0 other; gaaaaccgat ctcgttggtt tcttcaagca ttaggagtat tctcagtccc gccagttttt 60 tgtaaaggtt gtgaaacaag cgatatacgg cgtactggtt gtttcagtgc agttgtaatt 120 ataggactca gagtatgagt tggccatttg gaagaatgag aacttttgtt tttcgcgaca 180 ttagaatgca atgacaatga cgttaagcta tttcgggcat ctctcgaagg aacaagaaaa 240 gagcgatcgt tgttcatatt atgtttatct aaagattttt ccactttcgg tttcgaatct 300 ttattcttta tttcaacagg aggtacggaa ctagtagtgg gaacttcact aaatcgaact 360 cgtttcttca aaggcttctt tagaactcga gcagctttgg atggtgagcg agccttgaat 420 cgactaggag agcgaggtat ttcaaacatt gataatagag gtgcttttcc tttttcaatt 480 aaattgggaa cttgaatggt tggctctgaa ggtactattc caaccaattg gtcaaaggcc 540 cttgcaaggg attcattaac atcaatggca tttcctggta acagggggaa tagtaggaat 600 aggttctgga taagcttacg agacgttgaa gagaatgttt cagactcatg cttggcatca 660 agaatttggt tttcgataat agatttcaac aaatcgacgt cgtcttgcaa catgtcagca 720 tacatatcag ccccctcacc tttgaacgaa gacactatat gagaaatact gttttgaaaa 780 gttttgcaga tttcttctgg attaactttg gcagtaatca agcttctttg atcgtataac 840 tttgcaagtc ttgtttcgac agattttata ttatgccccg acatagcatc actttcctta 900 gcaatggaaa tccacatctt tgttaatgtg atttcatctt caatccttct caatgtacgt 960 acatgttcaa ttagtgattt ctgcagatcc cttgaaccat caaatgagtt tttgagcatg 1020 cttctagcat ctaacatttt aatttctcga gaagaaattt ttcgtacctc cttatttaaa 1080 gccaattgct tagactcttc agcaatcctc ttttgaagta tgctaacctt ttgtcgtaat 1140 tcgtaaatgg tgcgtacata ttcacttaca tgcctatcta cgctcaccac gtttctcgaa 1200 accttcgttt tgatgttttt ggctcgattg ccatacttta aggtattatg tgtctcatca 1260 taatgctccg acgacggtga gatacaaact atcatacacg tgcggcaatt tccgcctaaa 1320 ctgaacttta aaagacgagt caacttcgag tctctatatg gaacatgttg tcgacgacga 1380 ggttcgcaca acgagttgat gcaatttccc aatgccagta aagaccgatt gatgtttgct 1440 ccttctacta aacgtttgcc tctatttttc gttgcactcg ctctctctga gcctgctaaa 1500 tcaataaaag agaatacgga acggacttta tgggaatttt gggactctga ttcctcctgc 1560 ttctcacccg atttcggagt ttgcgtgata taaatctgta aaacggcatg cgagcgtgac 1620 gaaacagcat tggcttctgt tggtgacatg gttcgattac tgtttccacg aataataatc 1680 tccattactt cttccaaatt agttggtgta aaatatgaga gaccaggaac ggatacgttt 1740 tgctcagcat cttcacaaat atttaacgat tttggttttt ccatagaaag gggatcctgt 1800 actaaaagat ctcgaatctt ttcattatat atttcaagat atgagacact aatgtcgacg 1860 ttcatcgttc gcttgagtcc ttcaactcta tctaacaatg ccctcatcgt taaaaaaata 1920 atgcctggat cgtctggtct accactgatt gtgtgtgtct taccacatcc tgtagcacca 1980 tatgcaaaca cagtggcatt atatccctgc aaaacactgt ccaacaacgg ctctgtggta 2040 cccttgtaaa catcctcctg tgaggcttct tcaccaaaaa gacgatcaaa tgcatatcga 2100 acatcccgaa agcgtttccc tgcaggtaat agcgattttt ggactttggc caatggattt 2160 tcttcaggag gatcgaaaat tagcacgtta tcgtctaaaa cacgcacaat ttttcgaatt 2220 ccattcgtac aaaaagtatt cgaagatgta tttgacactg ccaaacttcc atctccaaga 2280 aattctttgg atttcggagt ttccgcgagc aatccctttt ctctttcagt aaacggtcgt 2340 acacgaactt gatggtcagt ttcgaaggat ttttttgaaa ttcttacctg caacggaaat 2400 tgaagaccct tctttcatag cagtatcgta atactgattc taggaatgaa tttgttttag 2460 ttgtgtgaag ctattaagaa gaacacaagt atgggaagct tgaaatgtaa acaatgaaaa 2520 aattaccaag aaaaatacaa gaaaaataaa ataaaactat taaaaataaa atatacaagt 2580 tatttatgta ttttaaatcc ccaaatagtt acttttatat ttagcagtca ctttttatga 2640 gttggtatcg aatttggtat agcattccaa tccagctaaa ttaacggtta acccagtagt 2700 aacggtaaaa tggcaggtgt tagcgtaaag gacgtcgatg ctcagcagtt tatcaatgct 2760 tatgctgctt ttttaaagcg ctccggtagg tagaagattg agctgttaat gggaactttt 2820 ggttgtagaa ggttttcatc tgtctgatca cagaataaga ttgtttagca tacgtgtgaa 2880 attgacagtg aacttgtagc ttattaacat ttactcactc atttctttct ataaagcaag 2940 tttctaactg atccgtaggt aaaatgacca ctcctcagtg gattgatatt gtcaagaccg 3000 gtactcacaa ggaattagct ccgtacgatc ctgattggta ctacgttcgt gctgccgcta 3060 ttgctcgtca catttacctt cgtaagcaag tcggtgttgg tcgtctctgc aaggtctatg 3120 gtggttccgt caaccgtggc atgcgtcctt ctcatcaccg tgatggatct ggcagtgtcc 3180 aacgcaaagt cgttcaaagt ttggaaaaaa tcggtgtcct cgagaagtcc gacaacggtg 3240 gccgtcgtat ctcacaacaa ggtcaacgtg acttggaccg cattgcatac tccttactcg 3300 aggatgaaga ataaaaaaag gaatagctta atcaataaat gatgtttcgt gggttgttat 3360 accattaatt gttttgtgta aaggtatgct gttctcgtaa ttactggtct tggcaccata 3420 acttcatagt acgtatatga ctgaagcgtc aatgtcagtg cgctattggt aaaatcatta 3480 agatttaaaa atatctgaag caagaattct ttattttttt tgtttggaat tcgtctagtt 3540 gaagcacttt cggtaatcgc agagctttag cgtctctcaa acgtctgttt tagctaatag 3600 ttaaaaaacg attatcctac caattcataa tcaaaatatc cttttgatga gtttatttag 3660 tcaacattat gtttgcttat tacaaatcgt ctctaattat tgtacctcat atattagcta 3720 aatatacaag gacaagggac aatattttat tatatcctgc tattaagatt atgcaaatag 3780 aagcattgaa gccaaaagaa agtaatgtaa tgtactctta tgctaaatgt ttgataattt 3840 aaactatatt gtagtgtttt ggtatttcaa attaaaggag aagcgcactc acaaaattga 3900 tgcagaaata taaatatata tatatacagt ttataaaatt aaaatgtggg atgaaaactt 3960 ggtacttttt ctcatgaagc aaacttggtg acttctcttc tccatgattt atgatgagaa 4020 aagctgacta acctttcaca tattaccttt ctaatgaatt ctttacggat gagcattttt 4080 tcttttaatt attgaacaat cagattatat tttcattaaa aaatcaaaaa atttgtaatt 4140 aaattgagac ttagagatta agaagcttgg tcattacaaa acccgtatcg acatctataa 4200 attgctttct tattgattgt ttcatttcta acaatagcca ttctcatttt ggattattat 4260 ttgatttttt gaattatcat actagggaaa taaaataaaa aaacttccgt aatggaaaat 4320 tcgtcaattg tcaagtcacc gaatccaaca atcgaggagc aaagaaatga aattgaaaag 4380 ttaaagaatc tcacaggtat agaagaggtt cacgttgatg gtgcaaaagt taataaaagg 4440 aagcgtactt ttgatgagca gtcggagata accaaagatt acatcgagta tgatttttcc 4500 aagattgaag atactaaagg tggttatctt cttgaagaaa agaaagttga agacttaagg 4560 gagaaaccgg ctgagcgaga gcttagagag caagaagaac gccaaaaaaa gcttaggcta 4620 gcacctctta atctagaccc agaaacggca ccaaaatgct tcgagtgcga ctccatagaa 4680 ttagacacaa aatattttga catttttcat tgtagggtgt gtcatacgtg tcgggagaaa 4740 tatccggata aatactcctt gctaaccaaa acggagtgca agttagatta tttgcttacg 4800 gaaccggaat tgcaagatca agaactttta cctcgactgt taaaggcaaa tccacatcag 4860 caaggctggt ccaacatgat gttatatctt cgctatcaag ttgaggaatt tgcaaagaaa 4920 aaatggggtt ctatggaagc tcttgacgcg gaatttgaga ggagagaagt acaaaagaag 4980 gagatgaaag agaagaagtt tgaaaagcag cttttggagc ttcgaaagag aacacggaca 5040 agtaattaca gtcgaatgag tattcgtgaa aagcgaaaac atgttcattc ttatgatgag 5100 gaatttgaga aacctaatga acccggtgta attgtacaaa gatgtaaatg tggcttggaa 5160 attgagcagc tggaaattta agtctttgtt ttttagactt tggatttgca cacctaactt 5220 ttttcaatgt aaatgctatc agatttcttc aaaaatcggg tttttttatt aatgatgttt 5280 caatgcagct atttatttat ttattttttc gacatacttc atgatattct cctttatgtt 5340 aagagaactc gcttaatggg aaaacttggg agtattaaag tcatttgttc gtattttttt 5400 ttatgaaaag tagactgctt gtaatagaaa agtactataa taatttaaat gatcactttc 5460 atttaatatg gtaaatgcca agttatcatt ctccactaaa cagatcttct tcaggaaaca 5520 gaccttttat ttttgacctg aaggtgtgat aaatcaggac attaagagaa atgaaattac 5580 aagtacagtt tctcatcttt tacatatttt cgttaatcgc cctataaggt agtatccctc 5640 ttaactgttt ctcacattaa atactcattc ctttctgtta gaaaattcaa agcgaatgtt 5700 cattcaaagc gtctcagcaa gtttttaagt agctttttgg caatttctcg ttcttgctct 5760 ctcatttctt caaacaattt ccctctattt aagcttaaaa ttagcgagtg tgatctagtg 5820 aggatgatag atcaaaatct tgacttctgc aaccgatgtc atgatcggcg gtagtctgac 5880 tgtggtattt caactatttc gcaagttttt agtcgtgaac ataaaaaaaa atattgagca 5940 tgaaaccttc atgctcatag tgaagacgat gcaagtcttc ttttgcaaac cgtatgattc 6000 tagcgaagca taggcctaag ttcgatcttt ctttcaatgc tgaggaaaga aggttaatgg 6060 tggatctaat acacctcttg ttccgatact cggaaactat ttaatattgc cgttcacttc 6120 gaatgtagaa gcttttgcta taaaatagca ctggtgaaaa aaaactattt tataacttta 6180 tacaatccaa cactaaggca tgtgtagtat tcatgagcaa ccggtaaaag atttgagtga 6240 tcaaacattc cagtcaagct acgctacaaa aatttcgaat gatcaagtga caatgaaaag 6300 caaaaaattt aaaagctcaa ctgaaaaaaa ataaaaactt accttgcatt tgcaaacgcc 6360 agcagcaaat caatagctat ttacacctat aacgcacttt aaagccagtt cgatatactc 6420 atattgggca acccaacatg tttttaacca tcagattatc tttgcacagc ctacagcgaa 6480 tattgcgtaa gatgcttagt ttatgtggta aaagaacttt ccaccgcaga aaaggaaagt 6540 atatatttta tacatttaca aacattttaa tacataaacc atttatttac aacattaaaa 6600 ttagtatgct tctattgttg ttgtataaat tttttgtcta tgcattcgat ctctgacgcg 6660 cacatagaag cctgcgcccg attcacaact tgccaactac catcaactgg ttttgttttt 6720 gtacccaatt atttaaggtg tcaaatgtct gctcaacagt tttatggtga taagggctat 6780 gtatggaatt tgttatgcag ctcagttgca acaatttatt caggatttta ctaacagctt 6840 caattttagg cccctgctcc tcctcaacaa gcttatggag gcccaaacta ttatcctcct 6900 caacaaaatt atcctcaaca aggttatgct cctccacaag gctatcctca aggtggatat 6960 cctgctcagc aacctatgta tgttcagcaa cctcaggcca gtgatcctgg tggcgatctt 7020 tgctgtggtc tgtaagtata aagaatgggc gcgtagaaga cgtcgaaatt gcattggaac 7080 ggtgaagcac actcttaatt ttgaaaggtg aatggggtat tctttattga attaggtcat 7140 tacgtcagtc gattaaagtt gctttggcgt tcctttcgaa tagttccctg ttgaactgtg 7200 ttttgcttta cctttttctc tttactaacg actgttttta gattgaccgg tcttgcttgc 7260 tgttgctgtt tggatgcaat gttttaaaaa actatttggc ttgttctttc tacttttctc 7320 gaaagagagc atgcaccact gattaaacta aaagccgtgt ttattttctg acttgagtgc 7380 aattaatgat tgttggttat tttttcatta attccctcgc cagcaaacaa ctttatggcg 7440 aggatttatt tatttacatt ggtaaagcgt tggtcgaata attatagatc ttgatttttc 7500 tgtacagagt gtcgtctcac tttttgaaaa ttgctattac ccaaccgttt aatttcagct 7560 tcttttcttc gaaattaaaa cctttagttt tatgatggac tgtcttttct attttttaag 7620 cgcaaaatct tttacagcat ccattggtct aaatcgttct ttatgaataa tttttagttt 7680 ggattagttg aaatgactcg tcctgaaaaa attcgcatgt ttatttatct tgcttaccct 7740 gaaggggcaa tatgtgtgtt tcgtttttag ctaacctttc tatggtttgt ctactttttt 7800 gctgctcgtt atatgttgtg tattctgttt agtatgctgt tgttttcttt tagtgtagat 7860 gaactcttta gatttcccaa tatgtttaag tttgatagag tcggtttttg atcgatacgt 7920 ataagaattc cttatttgtt ttttaaaaag attttaaaag taaattgagg catatatctt 7980 acgtaaaaag tttaaagttt ctaagatttg ctttgactat ttcaaacagg tagatagatg 8040 cgtgcttttt ctatggtgga aatacgacaa acttgttcac gaaaatgaag ctcaaccatt 8100 gcgacccccc ttgattcaaa tgctatgaat ttggatgcgc aagctcgtta agacaaaaat 8160 tgccatatga cttttattgc aatgagcgct atatctacaa atactcaata tcctttatca 8220 attacccatc tataagtatt atttataatc gtagtagtaa atgtatttca ttgcagctat 8280 actctacttc ctattcaatt acctcctcca tatagcgaaa agaccgttca cgatatcaca 8340 aagtttatta acatacaata acgagttcac atattaaaag aaatatgacg atacgcagtg 8400 tgtaaaatag tgtactgaga ggacgtccaa tgtaacatgc gatcgggttc tttattagtt 8460 tgttgtgttt gtgccatacg ttgaaaacca ccgaattggg aaatattgtt aaagttgggt 8520 tgtttggaca taattttgtt aaattcgttt aaattattta tatttttaat tatattttta 8580 catgcagaac aattcagaga tccgatagaa tgtcaggtaa ggaattccta tgtaaacaaa 8640 gctaatctca aaatttagaa actttgaaca ctccgccaac atatgcatgg gttttgaaag 8700 cattttctag taaattagca ggaactgtga cgaagcctgt tacaaaaatg tcctcttaca 8760 ttgaggatgc agaatctgat gcagaacttc cgcaagacgc aaaagaagac ctgcgcccaa 8820 ctgagacatt aactccgtta aaaagtaaag cagcacaaaa tgggattttg aaaactccag 8880 gtactttaca aataaagaag accgtcaatt tcaaagatat ttcaaaagat gctgcgacgt 8940 ggaatcgtcc aacgaaaaat aatttcttat ttacgagatt agatgatgag aatcctttaa 9000 tgggtcatga agaattcaaa tcccctttgt tacagagtac tccaaaaccg aatattaata 9060 atccggataa tgaaaacaaa agtaagcatg acgagtttga taatcgctat aatattaata 9120 tcaatgaatc ctataaaaat gagacaaaaa gcaatcagag attaggcgaa gatgtccctt 9180 caaagaaaaa atatcctcac tcgatggatg ccgagatctc taaattcaaa tgggatagta 9240 acaataataa tgactggtca agtttaatga aggattgctt tcgagatgtt gtgaacaata 9300 atcgaaaaat gaaggaaatt attaaagacg ttatgattga cacatcccaa gcttttccct 9360 ctgagagctt ggatgaacct gactatacga taaaccttga tgcgcctcgt tcctcttcag 9420 gaaaatactg gaagcaaaag tttagtatgc tagattctgc tcattcggat cttgagttag 9480 aattaacctc tatccgtgag cgtttggaat ccttaatttt agagaaacaa gaggaaatca 9540 atttttggaa acaacgttgt cgagctttag aaacggagaa aatccataat catcaaggac 9600 aacagtcaaa atacaaaggc aaggaattcg ttggaaatag atttagccaa atgagggagc 9660 tttatactgc taagccaagt ccgattacta ctaaagttgt ttctaggcca tcccaatctg 9720 atgtgcgtga gcctcaagaa caggttcctt ccaagaattt acatcgggga gcagatatgt 9780 cgcatttggc agctcaaatg ctgactcatt catcaaaaaa gtcccatacg acaaacctaa 9840 taccttctga aggaataatt tcatcaactc ctatttccgc agcttccaaa gtacgtatga 9900 atttaatgca gtctaatcaa actcctacac ctgctccatt ttcaatagca gcaaagaagt 9960 cccacttacc gtcgaaactt agtttcccac aagatggtgg tagcttatct tctgctacta 10020 ccttgcagca attgccaaaa gcaagagtga cgccaaacgt gttatcttct ttaagctcaa 10080 accttggaaa aacaaatcca acgtcagtat accaatcaaa agcgaacgta actacaagtg 10140 ctgatgttga aaaaccacaa gttaaagttg caactagttc tcgcgtggat tatgatttga 10200 agagtccaaa tcaacgtact gcgaatgcaa agaaaagatt agaggaaagg agaagacgaa 10260 ggaagttgaa acttcaagaa cttcagttga attcctgaag gtataatttt actagatcga 10320 tattgtataa ttagaatgca tatccttttt aagtaaagga ctggagcctt agtttcattt 10380 atttttgttg aggaaaggtg tgtgcatcaa gtattgaaaa ttaactatat tcctttcgag 10440 aattaaataa aatataagtc cattattaat attaactcaa attactaatt tttagtataa 10500 atgatggatt cattataaga ggcttgtaaa aggccgtatt agtcgtggat attgtaattt 10560 aatttcatct tttcatgcag tattttacta gaaaaacatt cagctgtaca tttagatcgt 10620 aagctgactg gaagaattcc atctcctcaa cctccatttg aatcttgtct taggccatac 10680 gcagtaaaaa cttgaaagta gcaacaattt catattacca cactacgata ggttattaaa 10740 tgggaaaatg ggtgtcttag aaaaagtaaa taaaaatatc tgccgttata tactaatcta 10800 aattggctag attcaagaga ttgaagctga aatgcgccgg acgcaaaaaa ataaggcgac 10860 ggagtaccat cttggtttgg taagtttttt taattcattt ctaactggaa tgccttttat 10920 tttatagcaa atattacaat gttgttccaa cttataaaga atcaactcta aattaaacta 10980 acctagtcct ttagttgaaa ggaaaactcg ccaagctgag ggctcaatta cttgaaccta 11040 cttcaaaatc ggggccaaag ggggagggct tcgatgtttt gaaaagtggt gatgctagag 11100 ttgcatttat tggatttcca tctgttggta aatctacttt gctgtctgct attacgaaaa 11160 cgaaggtttg ctatttcttt ttaaatactt tattttttta ctaacaatgg taatatagtc 11220 ggcgactgca tcttatgaat tcactacttt aacggctatt ccaggtgtac tcgaatacga 11280 tggagcagaa attcaaatgt tagatcttcc aggtatcatt gaaggtgcct ctcagggaag 11340 aggtggccgc caagcagtat ctgctgcacg cacagctgat ttaattttaa tggttttgga 11400 tgctacaaaa gctgccgatc agcgagaaaa aattgagtat gaacttgaac aagttggcat 11460 tcgtttaaat cgacaaccac caaatgtgac ccttaccata aaaaaaaatg ggggcattaa 11520 atttaatcac actgttcctc taactcatat ggattacaaa atggcataca atattttaca 11580 tgaatacaga atccacaatg cagatatcct aattcgtgaa gacatcaccg tggatgactt 11640 tattgatctt gttatgggaa atcggcgata tatcaattgt ctgtattgtt atagtaagat 11700 tgatgccgtt tcgttggaag aagtggaccg acttgctcgt ttaccaaagt ctgtcgttat 11760 tagctgtaat atgaagctga atcttgactt tcttaaagag cgcatttggg aagaactcaa 11820 tctctacaga atatatacta aacggaaagg agaaatgccc gacttctctg aagccctgat 11880 tgtgcgcaag ggatcaacaa tcgagcaagt ctgtaatagg attcacagaa cattggctga 11940 acaattaaaa tatgcacttg tatggggtac ttctgcaaaa catagtcccc aggttgttg 11999 //