ID   SPBC543    standard; DNA; FUN; 21027 BP.
XX
AC   AL391604;
XX
SV   AL391604.1
XX
DT   24-AUG-2000 (Rel. 64, Created)
DT   24-AUG-2000 (Rel. 64, Last updated, Version 1)
XX
DE   S.pombe chromosome II cosmid c543.
XX
KW   anion exchange; atp-dependent rna helicase; coiled-coil; DNAJ domain;
KW   helicase; mapk kinase skh1; respiratory chain; ribulose-1,5 bisphoshpate;
KW   septin; spn3.
XX
OS   Schizosaccharomyces pombe (fission yeast)
OC   Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes;
OC   Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
XX
RN   [1]
RP   1-21027
RA   Wood V., Rajandream M.A., Barrell B.G., Saunders D., Harris D.;
RT   ;
RL   Submitted (24-AUG-1999) to the EMBL/GenBank/DDBJ databases.
RL   European Schizosaccharomyces genome sequencing project, Sanger Centre, The
RL   Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail:
RL   barrell@sanger.ac.uk
XX
DR   GOA; P48008; P48008.
DR   GOA; Q9HGM3; Q9HGM3.
DR   GOA; Q9HGM5; Q9HGM5.
DR   GOA; Q9HGM6; Q9HGM6.
DR   GOA; Q9HGM7; Q9HGM7.
DR   GOA; Q9HGM8; Q9HGM8.
DR   GOA; Q9HGM9; Q9HGM9.
DR   GOA; Q9Y884; Q9Y884.
DR   SPTREMBL; Q9HGM1; Q9HGM1.
DR   SPTREMBL; Q9HGM2; Q9HGM2.
DR   SPTREMBL; Q9HGM3; Q9HGM3.
DR   SPTREMBL; Q9HGM4; Q9HGM4.
DR   SPTREMBL; Q9HGM5; Q9HGM5.
DR   SPTREMBL; Q9HGM6; Q9HGM6.
DR   SPTREMBL; Q9HGM8; Q9HGM8.
DR   SPTREMBL; Q9HGM9; Q9HGM9.
DR   SWISS-PROT; P48008; SPN3_SCHPO.
DR   SWISS-PROT; Q9HGM7; YW04_SCHPO.
DR   SWISS-PROT; Q9Y884; SKH1_SCHPO.
XX
CC   Notes:
CC   Details of yeast sequencing at the Sanger Centre are available on
CC   the World Wide Web.
CC   (URL, http://www.sanger.ac.uk/Projects/S_pombe/)
CC   During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced
CC   by the Sanger Centre.  The sequencing of the S. pombe genome is now
CC   being continued with funding from The European Commission.
CC   Fourteen European sequencing laboratories, including the Sanger Centre,
CC   are participating in the project.
CC   Protein coding regions (CDS) have been predicted with the help
CC   of computer analysis using the Genefinder program in PomBase
CC   (an ACEDB database) with additional predictions for the
CC   branch-acceptor sites supplied by the program Sp3splice.
CC   CAUTION: It is possible that for any individual CDS we may have
CC   underestimated or overestimated the number of introns/exons or
CC   we may not have chosen the correct splice donor/acceptor sites.
CC   CDS are numbered using the following system eg SPBC25H2.01c.
CC   SP (S. pombe), B (chromosome 2), c25H2 (cosmid name),
CC   .01 (first CDS), c (complementary strand).
CC   The more significant matches with motifs in the PROSITE
CC   database are also included but some of these may be fortuitous.
CC   The length in codons is given for each CDS.
CC   IMPORTANT: This sequence MAY NOT be the entire insert of
CC   the sequenced clone.  It may be shorter because we only
CC   sequence overlapping sections once, or longer, because we
CC   arrange for a small overlap between neighbouring submissions.
CC   Cosmid c543 is overlapped at the 5' end by cosmid c16A3,
CC   EMBL entry SPBC16A3, accession number AL021748, and at the 3'
CC   end by cosmid c16C6, EMBL entry SPBC16C6, accession number AL021767.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..21027
FT                   /chromosome="II"
FT                   /db_xref="taxon:4896"
FT                   /organism="Schizosaccharomyces pombe"
FT                   /strain="972h-"
FT                   /clone="cosmid c543"
FT                   /map="IIR"
FT   misc_feature    1..83
FT                   /note="nominal overlap with  SPBC16A3 S. pombe chromosome
FT                   2"
FT   CDS             join(complement(949..1255),complement(544..722),
FT                   complement(1..480))
FT                   /db_xref="GOA:P48008"
FT                   /db_xref="SWISS-PROT:P48008"
FT                   /label=spn3
FT                   /note="SPBC543.01c, "
FT                   /partial
FT                   /gene="spn3"
FT                   /gene="SPBC543.01c"
FT                   /gene="SPBC16A3.01"
FT                   /product="septin homolog"
FT                   /protein_id="CAC05243.1"
FT                   /translation="MWYTYNEDFGVVQLLFLHSNDTLTARTHITKGQIDIELTMRTTKK
FT                   SSKKGIPLNLMVVGDVGLGRTAFINTLCEKPLIRHNNNFDPAEASSVSPVEIVPYQTDI
FT                   ILEDGTKINLTVLDTPHFGEAIDNENNFDIILQYIESQYDNVLEEESRIKRNARFCDDR
FT                   VHALIYFISPTGHGLRELDIELMRRLAPRVNIIPAIAKADSLTAQELQTTKEMINADIE
FT                   YYKIPVYDFPYDIEEDEEAIINLSQQLRATIPFAIVSSDRLIEMNGQTVRGRAYPWGVV
FT                   EVDNPRHSDFLALRSALFATHIEDLHNITSNQLYETYRTEK"
FT   misc_feature    complement(4..480)
FT                   /note="Match to PF00735 GTP_CDC, Cell division protein
FT                   Score 364.94"
FT   misc_feature    complement(481..497)
FT                   /note="ctaacaatcactcatag, splice branch and acceptor"
FT   intron          complement(481..543)
FT                   /note="Intron confirmed by mRNA"
FT   misc_feature    complement(538..543)
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    join(complement(949..1111),complement(544..722))
FT                   /note="Match to PF00735 GTP_CDC, Cell division protein
FT                   Score 190.85"
FT   misc_feature    complement(723..738)
FT                   /note="ctaacgaaaactaaag, splice branch and acceptor"
FT   intron          complement(723..948)
FT                   /note="Intron confirmed by mRNA"
FT   misc_feature    complement(943..948)
FT                   /note="gtaaga, splice donor sequence"
FT   CDS             complement(1871..3301)
FT                   /db_xref="GOA:Q9HGM9"
FT                   /db_xref="SPTREMBL:Q9HGM9"
FT                   /label=SPBC543.02c
FT                   /note="SPBC543.02c, len:477, SIMILARITY:Homo sapiens,
FT                   TTC2_HUMAN, tetratricopeptide repeat protein 2, (484 aa),
FT                   fasta scores: opt: 828, E():0, (40.1% identity in 479 aa)"
FT                   /gene="SPBC543.02c"
FT                   /product="DNAJ domain protein similar to human
FT                   tetratricopeptide repeat protein and protein kinase
FT                   inhibitors"
FT                   /protein_id="CAC05244.1"
FT                   /translation="MTEVETTHMNAGTESQQEPAELAEKQKAIGNAFYKEKKYAEAIKA
FT                   YTEAIDLGSDSALAIYYSNRAATYMQIGEFELALCDAKQSDRIKPDVPKTQSRIRQAYE
FT                   GLSILNEAEVYLKNKQAGLALNALDRLQRRIDSTTQPPMSWMYLKAQVYIFQNDMDRAQ
FT                   KIAHDVLRLNPKNVEALVLRGKVMYYSGENAKAITHFQEALKLDPDCTTAKTLFKQVRK
FT                   LENTKNQGNDLFRQGNYQDAYEKYSEALQIDPDNKETVAKLYMNRATVLLRLKRPEEAL
FT                   SDSDNALAIDSSYLKGLKVRAKAHEALEKWEEAVRDVQSAIELDASDANLRQELRRLQL
FT                   ELKKSKRKDHYKILGVSKEATDIEIKKAYRKLALVYHPDKNAGNLEAEARFKEVGEAYT
FT                   ILSDPESRRRFDSGVDLEPGMEGGAGMDPFDILRAYQAGGSFPGGGFPGGGFPGGSYNS
FT                   QGFGMGGGFPGFTSFQFS"
FT   misc_feature    complement(2063..2257)
FT                   /note="Match to PF00226 DnaJ, DnaJ domain Score 131.90"
FT   CDS             join(complement(5925..6053),complement(5826..5880),
FT                   complement(5704..5770),complement(3827..5663))
FT                   /db_xref="GOA:Q9HGM8"
FT                   /db_xref="SPTREMBL:Q9HGM8"
FT                   /label=SPBC543.03c
FT                   /note="SPBC543.03c, len:696, SIMILARITY:Xenopus laevis,
FT                   Q9W627, human ku80 autoantigen homologue, (726 aa), fasta
FT                   scores: opt: 499, E():1.1e-23, (24.1% identity in 688 aa)"
FT                   /gene="SPBC543.03c"
FT                   /product="putative DNA helicase"
FT                   /protein_id="CAC05245.1"
FT                   /translation="MSDKECTVFVLDLGKDMGTCHHGRSHSDLEWTLSYFHDELSHKFL
FT                   ANRKTDVVGIVGYKCDDTKNDLAEQEAYWNISVLYPIQTALFSKLQSVSQTLKPSNTMQ
FT                   GDLISAIVVSFDLMARHCKKNKWKKKMIVLTAARGIIDFSDYIGIAEQLLQHDVFLGVY
FT                   GVDFDQEDINYSEPLKESQKKENEVRIQEFVESCHGQYCTFQQIYNNIGKPWVRKVRPV
FT                   AIFRGTFSIGNRDSKDTSISIQVERYPRTRLTKPPTSSAFYENDMSKNYECLNIENSNV
FT                   ENKSMESDAVSTVRSYMVRDPKTNDSFEVKREDLESGYSYGRTIVPISRSDEDVLALDT
FT                   IPGYEILGFIPKSSLPIYYTISDTNIIVPKDDFESKLNFSAFVQSLEREHRYALARFVS
FT                   KDKGVPVLLVLMPYVEFKRHYLVDIQLPFAEDVRPYSFSEFEKLSNEEDMRQIDFAVSN
FT                   YIDNMDLDSSDCGFNPPFEPENTFSMIPHRLQQAISYYANSPEGDLPQPNIYLTRYTNP
FT                   PKSLLDNCILDLKLIKEKLTVNVPVKPKYSSQETAFDTGAPISEEQIEELLNSGLDEQE
FT                   GEKLLVLHVSEKDPVGTFTEVLKNPFGLEDALTEMEKVIKNLIDKSKYDLALQSLQSLR
FT                   LHSILEDEVERFNEYLTRLKKDVMQNNKPKENELINKIRSSGLDIILHDELTRHDNFNN
FT                   I"
FT   misc_feature    complement(5664..5679)
FT                   /note="ttaacttcttaactag, splice branch and acceptor"
FT   intron          complement(5664..5703)
FT                   /note="Intron confirmed by TSE"
FT   misc_feature    complement(5698..5703)
FT                   /note="gtaagc, splice donor sequence"
FT   misc_feature    complement(5771..5790)
FT                   /note="ctaacttttacggtgtttag, splice branch and acceptor"
FT   misc_feature    complement(5820..5825)
FT                   /note="gtattc, splice donor sequence"
FT   misc_feature    complement(5881..5895)
FT                   /note="ttgacacatactcag, splice branch and acceptor"
FT   misc_feature    complement(5919..5924)
FT                   /note="gtattt, splice donor sequence"
FT   CDS             join(6715..7778,7844..8537)
FT                   /db_xref="GOA:Q9HGM7"
FT                   /db_xref="SWISS-PROT:Q9HGM7"
FT                   /label=SPBC543.04
FT                   /note="SPBC543.04, len:586, SIMILARITY:Homo sapiens,
FT                   Q12980, hypothetical 63.6 kda protein., (569 aa), fasta
FT                   scores: opt: 225, E():1.9e-07, (22.2% identity in 613 aa)"
FT                   /gene="SPBC543.04"
FT                   /product="hypothetical protein."
FT                   /protein_id="CAC05246.1"
FT                   /translation="MVRLTPRLVAIFLVEKTTSGANFVFHWPLQPQVRLQATHHNNDSA
FT                   ESAIGMLDLDDSDDDENNRFTEVADDTHVLGYEKGFLANMLSPRIELCNQKFEIWVDGL
FT                   TFLGCPVHIGPNGEWAKRRKPRTTVESNASSSHLVSKPESSHPSTGSFEVKSSSSKSRS
FT                   SMSLFHVVFVLNVPTATVYRPTVNTMYDHIVVKLVTGLKYEQAKRNYVENECIHILKLT
FT                   EKYSSQNVPFDVYAAQIPHHSNLASVLATTYEALINMHTAYLEINQSINLSLLWPMSVS
FT                   TNTLENYELQVRPSTILASQTIFSEEHPSSIEPFVAPYWTLLLLKDTDTIMKRVPLLQN
FT                   SLLSSFIAIVKPNLTFTDIANRLGISVSECFILAKHLIHWRKAIAIPPLLIRNTYVTSP
FT                   TANLFNLEEESKLFKKEFPSLPSLSTFLAILSFKPRPFASIIPSKDHELVYLEMLAWLC
FT                   RRNWVYEQNIYMYILVPEEIKKKAIALIESDESSKNDMQLRKQLEQDNGKESIIIDPHS
FT                   ASLLEQKWIQIIAYERGPEMAPLFTSIVKYLNGRFALQTIWVAEGLPRKLMRNILNEYN
FT                   DYILRWHSW"
FT   misc_feature    7779..7784
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    7825..7843
FT                   /note="ctaacttacaatatttcag, splice branch and acceptor"
FT   CDS             join(complement(10362..10510),complement(9995..10294),
FT                   complement(9502..9937),complement(9119..9463),
FT                   complement(8742..9065))
FT                   /db_xref="GOA:Q9HGM6"
FT                   /db_xref="SPTREMBL:Q9HGM6"
FT                   /label=SPBC543.05c
FT                   /note="SPBC543.05c, len:518, SIMILARITY:Saccharomyces
FT                   cerevisiae, YN15_YEAST, hypothetical 65.0 kda protein in
FT                   met2-sec2 intergenic region., (576 aa), fasta scores: opt:
FT                   1124, E():0, (47.2% identity in 509 aa)"
FT                   /gene="SPBC543.05c"
FT                   /product="anion exchange family protein"
FT                   /protein_id="CAC05247.1"
FT                   /translation="MNKKDKKFNYIFGSEIVNDVKKRLPYYKSDWIDACHYRVLPACLN
FT                   IYFSNLLPELAFALDMFAKTNNSFGVNEVLLASVLGSVVFALLSSQPLCIVGVTGPITV
FT                   FNYTVYDIMHDRGTPYFPFLCWICLWSMIFHFIIAIANGVYFVKHITKFSCEIFGLYVA
FT                   FIYLEKGVQVLCDQLKYGLTNTFLSITIALLFLMVGWLCDTVGKSSLFSYKVRILLLDY
FT                   GLVASIIFFSGFQHIGKMREVSLAKLPTTKAFEPTLSRSWFIKFWKIPVGDVFLAIPFS
FT                   IVLTILFYFDHNVSSVMAQDPSFPLTKPAGFHWDFFLLGITTGVSGILGIPAPNGLIPQ
FT                   APMHTAALCVKRVDYDEDEIEKTHKEVIDRVVEQRASNFIQGLMTVGTMTGPLLLVLHQ
FT                   IPQCVLAGLFWVMGFSAIFGNGITQNVIWMLSDRKVVSKNHTLNHCSSKRVVWLYTILQ
FT                   LIGFGATFAITQVDKASIGFPIIILLLIPFRTYCMPKWFLEEDLEILDENVGIIAYQKV
FT                   "
FT   misc_feature    complement(9066..9080)
FT                   /note="ctaactgaattttag, splice branch and acceptor"
FT   misc_feature    complement(9113..9118)
FT                   /note="gtattt, splice donor sequence"
FT   misc_feature    complement(9464..9476)
FT                   /note="ttaacattagtag, splice branch and acceptor"
FT   misc_feature    complement(9496..9501)
FT                   /note="gtatgt, splice donor sequence"
FT   misc_feature    complement(9938..9954)
FT                   /note="ctaattgaaaactgtag, splice branch and acceptor"
FT   misc_feature    complement(9989..9994)
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    complement(10295..10307)
FT                   /note="ctaaacttgctag, splice branch and acceptor"
FT   misc_feature    complement(10356..10361)
FT                   /note="gtatgt, splice donor sequence"
FT   CDS             join(complement(12313..12442),complement(12122..12245),
FT                   complement(10925..12032))
FT                   /db_xref="GOA:Q9HGM5"
FT                   /db_xref="SPTREMBL:Q9HGM5"
FT                   /label=SPBC543.06c
FT                   /note="SPBC543.06c, len:454, SIMILARITY:Saccharomyces
FT                   cerevisiae, DBP8_YEAST, probable atp-dependent rna helicase
FT                   dbp8., (431 aa), fasta scores: opt: 1580, E():0, (55.5%
FT                   identity in 427 aa)"
FT                   /gene="SPBC543.06c"
FT                   /product="atp-dependent rna helicase"
FT                   /protein_id="CAC05248.1"
FT                   /translation="MSEHTRKSFSDLGISPWLIDTLKALAIYEPTDIQEGVIAQILEGR
FT                   NCIGGAKTGSGKTAAFALPIIEKWSKDPSGIFALILTPTRELAIQIDEQFAALGANLNL
FT                   KHALIVGGMDMIRQSIDLSKRPHVVVATPGRLADLIRSNGEETIAGLRRIKFLVMDEAD
FT                   RLLSPTFADDLDDCFSVLPASEDRQTLLFTATVTDAIRQLKYQPQKNNKPPLWLYEVET
FT                   DNISVPSTLQQSYIFVSSQVREAYLVHLLTIPENAKKSAIIFVNRTRTAELIYSILRLL
FT                   ELRVTELHSEMVQRERINSLGRFRAEAAKILVATDVASRGLDIPSVQLVINFDLPRDPD
FT                   DYIHRVGRTARAGRSGESISIVTERDVDLVHAIEDRVGTKLSEYEHVSENKMLEYIKEV
FT                   TDAKRQASLEMIDRGFGERRQKRNEKRLMANGISNKLKNSGRKKKAKNTLSTEK"
FT   misc_feature    complement(11228..11473)
FT                   /note="Match to PF00271 helicase_C, Helicases conserved
FT                   C-terminal domain Score 123.11"
FT   misc_feature    join(complement(12313..12379),complement(12122..12245),
FT                   complement(11675..12032))
FT                   /note="Match to PF00270 DEAD, DEAD/DEAH box helicase Score
FT                   137.10"
FT   misc_feature    complement(12033..12045)
FT                   /note="ctaactcgaacag, splice branch and acceptor"
FT   misc_feature    complement(12116..12121)
FT                   /note="gtataa, splice donor sequence"
FT   misc_feature    complement(12246..12266)
FT                   /note="ctaacaaataaaaatttatag, splice branch and acceptor"
FT   misc_feature    complement(12307..12312)
FT                   /note="gtatgc, splice donor sequence"
FT   CDS             13449..14540
FT                   /db_xref="GOA:Q9Y884"
FT                   /db_xref="SWISS-PROT:Q9Y884"
FT                   /label=skh1
FT                   /note="SPBC543.07, len:364"
FT                   /gene="skh1"
FT                   /gene="SPBC543.07"
FT                   /product="mapk kinase skh1"
FT                   /protein_id="CAC05249.1"
FT                   /translation="MSKKPVLNLDTSNGFSEEYISHPERNDNQGIVEITDLVFSSESKL
FT                   TQRKESRDSKTFVPSFLEELDDDHLHELVTNGGILYMNSLGEGVSGSVRKCRIRGTQMI
FT                   FAMKTVLAAPNTALQKQLLRELKINRSCTSPYIVKYYGACYNNAECQLNIAMEYCGAGS
FT                   LDAIYKRVRSQGGRTGERPLGKIAFGVLSGLSYLHDRKIIHRDIKPSNILLTSKGQVKL
FT                   CDFGVSGELVNSLAGTFTGTSYYMAPERISGGSYTISSDIWSLGLTLMEVALNRFPFPP
FT                   EGSPPPMPIELLSYIINMPPPLLPQEPGIKWSKSFQHFLCVCLDKDKTRRPGPQKMLTH
FT                   PWVKAFERIHVDMEEFLRQVWSD"
FT   misc_feature    13701..14477
FT                   /note="Match to PF00069 pkinase, Eukaryotic protein kinase
FT                   domain Score 273.60"
FT   CDS             15174..15926
FT                   /db_xref="SPTREMBL:Q9HGM4"
FT                   /label=SPBC543.08
FT                   /note="SPBC543.08, len:251, SIMILARITY:Drosophila
FT                   melanogaster, Q9VRJ2, cg10671 protein., (423 aa), fasta
FT                   scores: opt: 210, E():6.3e-07, (31.1% identity in 183 aa)"
FT                   /gene="SPBC543.08"
FT                   /product="hypothetical protein"
FT                   /protein_id="CAC05250.1"
FT                   /translation="MTEKTASHYWNEETSILKLRRKDILLFEIYATTLLLGSIYSIYVD
FT                   KWSITSYFGNSKNLINLIFVKRGWFWTSLVYFYHAWDQKRNKIDFKFISRYIVATLWWM
FT                   FVTQWFIGPGLIDRTFALSGGSCKNFDGDSSVFIPLTASTCKGLNGSWSGGHDLSGHVF
FT                   LLTHSSLFMLSENFSFILNNGIKATSTKVLFGLLGLWWWMLFVTASFYHTTFEKCTGFF
FT                   SGILEWSIVYVFSSRMPAVADLLGSSDY"
FT   CDS             16974..19295
FT                   /db_xref="GOA:Q9HGM3"
FT                   /db_xref="SPTREMBL:Q9HGM3"
FT                   /label=SPBC543.09
FT                   /note="SPBC543.09, len:774, SIMILARITY:Saccharomyces
FT                   cerevisiae, RCA1_YEAST, mitochondrial respiratory chain
FT                   complexes assembly protein rca1(ec 3.4.24.-), (825 aa),
FT                   fasta scores: opt: 2363, E():0, (56.9% identity in 664 aa)"
FT                   /gene="SPBC543.09"
FT                   /product="putative mitochondrial respiratory chain
FT                   complexes assembly protein"
FT                   /protein_id="CAC05251.1"
FT                   /translation="MRNPFLTFRAPTRKTGDYLVSKFVKKDNFSSLRLARAYTFSTRST
FT                   AVSQFSLLSLSQRSFQSLKINKGIPEKHKIPLISSKQFSVTSKRSQNGSSGSNSDANGR
FT                   KNGQKNDDSKKKGLNGNDPKKVFEIALNGNTILGGILVAYILYNVLSPNANMQEITWQD
FT                   FRQQFLDKGLVERLVVVNRNMVRVILRGGVASGSGQYYFSIGSIDSFDRKLEDAQRQLG
FT                   IPPSEFVPVAYHDEVSVLATLLSFAPTLLIIGSVIYLSRRASGAAGGGQGGIFGIGKSR
FT                   AKMFNHETDIKIKFADVAGVDEAKEEIMEFVKFLKNPKFYERLGAKIPRGAILSGPPGT
FT                   GKTLLAKATAGEANVPFLSVSGSEFLEMFVGVGPSRVRDLFATARKNAPCIIFIDEIDA
FT                   IGKARGRGGQFGSNDERESTLNQLLVEMDGFTSSEHIVVFAGTNRPDVLDPALLRPGRF
FT                   DRQITIDRPDIGGREQIFKVHLKHIKAADNIDLIAKRLAVLTSGFTGADIMNVCNEGAL
FT                   IAARSNSNEVQMVHFEQAIERVTAGLEKKSRVLSPEEKNTVAHHEAGHAVAGWFMEYVD
FT                   PLLKVSIIPRAQALGYASYLPKDQYLMSRGQILDQMGMALAGRVSEEIFFGPEKITSGA
FT                   SDDFQKVTRMAQAYVTQYGMSPTVGTIAYPIDTRETVQKPFSEATAQMIDEEIRKLVKH
FT                   AYERTKKLLLEHKQGLENIAQRLLQKEVITYNEVETILGPRPYAYKHLNISELMRQSEY
FT                   KNDHDPRNPPIPPSPQQPSA"
FT   misc_feature    17964..18536
FT                   /note="Match to PF00004 AAA, ATPases associated with
FT                   various cellular activities (AAA) Score 321.51"
FT   misc_feature    18552..19166
FT                   /note="Match to PF01434 Peptidase_M41, Peptidase family M41
FT                   Score 372.40"
FT   CDS             join(19633..19719,19768..20134,20228..20289)
FT                   /db_xref="SPTREMBL:Q9HGM2"
FT                   /label=SPBC543.10
FT                   /note="SPBC543.10, len:172, SIMILARITY:Homo sapiens,
FT                   CAB90454, tryptophan rich protein, congenital heart disease
FT                   5 protein chd5., (174 aa), fasta scores: opt: 167,
FT                   E():0.00045, (22.1% identity in 149 aa)"
FT                   /gene="SPBC543.10"
FT                   /product="putative coiled-coil protein simialr to human
FT                   congenital heart disease 5 protein chd5."
FT                   /protein_id="CAC05252.1"
FT                   /translation="MMDLIISTILLSLFIHFFDKFAKKRTIDGAYRIYVSVSNNKDLKK
FT                   NKEILEQLLTVKKELNATSSQDQFAKWARLNRKYEQLSQEWEKQSANVKIFQDTFKRVL
FT                   SLFLWILTRGFRFYIQFKESKTPVFFLPAFLLPSWALWVLSLPRSIYGSVSLTVWNFAV
FT                   QKTISGIF"
FT   misc_feature    19720..19725
FT                   /note="gtaatt, splice donor sequence"
FT   misc_feature    19753..19767
FT                   /note="ctaataatgtgaaag, splice branch and acceptor"
FT   misc_feature    20135..20140
FT                   /note="gtatgt, splice donor sequence"
FT   misc_feature    20212..20227
FT                   /note="ctaacatggcatgtag, splice branch and acceptor"
FT   CDS             complement(20806..21027)
FT                   /codon_start=1
FT                   /db_xref="SPTREMBL:Q9HGM1"
FT                   /label=SPBC543.11c
FT                   /note="SPBC543.11c, len:74"
FT                   /partial
FT                   /gene="SPBC543.11c"
FT                   /gene="SPBC16C6.01c"
FT                   /product="similar to ribulose-1,5 bisphoshpate carboxylase"
FT                   /protein_id="CAC05253.1"
FT                   /translation="KAIEFLQMLCQKRISRFKNGGLTAEAYKTLLCDPTLKRENRSRLV
FT                   LQIFYHELNLLEKSMQETIYLCTENFED"
FT   misc_feature    20928..21027
FT                   /note="Nominal overlap with SPBC16C6 S. pombe chromosome 2"
XX
SQ   Sequence 21027 BP; 6709 A; 3845 C; 3605 G; 6868 T; 0 other;
     cttttcagtt cgataagttt catacagttg attgcttgtg atgttgtgta agtcctcaat        60
     atgtgttgca aataaagcag atcgaagagc cagaaagtca gaatgccttg ggttatcgac       120
     ttcaacgaca ccccaaggat aagctcttcc acgaaccgtt tgcccattca tttcaattaa       180
     ccgatctgaa ctcacaatag caaatggaat agttgcacgt aactgttgac ttaaattaat       240
     aatagcttcc tcatcctctt caatatcata agggaaatcg tagacaggaa ttttgtaata       300
     ctcaatatcg gcattaatca tttctttagt cgtttgaagt tcttgagctg ttaaagaatc       360
     agctttcgca atagcgggaa ttatgttcac acgcggagca agtcttcgca tcaactctat       420
     gtctaattcc cttaaaccat gccctgtagg cgaaataaaa tatatgagag catgaaccct       480
     ctatgagtga ttgttagtat ggagcttaac taaaaatttt cacctaatcg taatgttact       540
     tacatcgtcg caaaatctag catttcgctt gatccgagac tcttcttcta agacattgtc       600
     atattgactt tcaatatatt gaaggatgat gtcaaagttg ttttcgttat cgatagcttc       660
     cccaaaatgg ggtgtatcta aaacagttaa attaatcttt gtaccatctt ccagtataat       720
     atctttagtt ttcgttagca atttcttttt acaaaatata agatagctgg ctgaagtgac       780
     tgcccaggga aaaattgaaa tccattctag attataattt gatacaataa atataaaata       840
     tcaaggttat taacgagtta tgcactgtta acaaaatcaa gtttgtagag ttcaagtcgt       900
     actcttacaa atgaatatca cattgaaaag cctttatgca aatcttacct gtttgatatg       960
     gaacgatctc aacgggagag acgctagatg cctccgcagg gtcaaaatta ttgttatgtc      1020
     gtataagtgg tttctcacat aaagtattta taaacgcagt tcttccaaga ccgacatctc      1080
     caacaaccat caggttcaag gggattcctt tctttgaact tttcttagtc gtccgcatcg      1140
     ttaattctat atcaatttgc cctttggtaa tatgggttct tgcagtgagt gtgtcatttg      1200
     aatgtagaaa caaaagttgc actactccga agtcttcgtt atatgtatac cacatttcac      1260
     tacgatcttt tatcaatacc gtgtcatagt aaggtaggat gaacaatcaa agaatgtatt      1320
     gtacgttgta aaagaaaatg gtaattacag aaaaattagt tacaatgatt attgtacctt      1380
     tttagcttaa cgacacaatt cagcaatagt tacttcacat aaaccaactg acgactgctt      1440
     ataaatagta ttaaattaag aacattaatc gggaaacacg aaacgattac ttttaatgaa      1500
     accacaatac tagcggtaaa taacataagc agtttaatat tgataagcag atttatttac      1560
     aatacgatca agattccaaa tgatttatgg ctcgacaaac gctaaacgta aatcaacaac      1620
     atccgggaaa aaactgcaaa gatagataca gaaaacaaaa aaaaattcgg gcgtaataga      1680
     atacatatta ggtatcggtg taattacaat ccgaagttgt ctgactcacg aattgaacac      1740
     attcacgagt tttttttttt aatagatgaa atgtgtaata atgaaagata ggtcggaaaa      1800
     agttatgaat ctaaaaaaaa agataggaag aatgaaaacg gtataaacaa atcgtgaatt      1860
     cttttccaac ttaagaaaat tgaaaacttg taaatccagg gaaaccaccc cccatgccaa      1920
     atccctgaga gttgtacgaa cctcccggga aaccaccgcc tgggaaacca cctcctggaa      1980
     aactacctcc ggcttggtaa gcccgaagaa tatcaaaagg atccattccg gcacctccct      2040
     ccataccagg ttcaagatcg acacccgaat caaaacgacg tcggctttct gggtcagaaa      2100
     gaatagtata agcctcgcca acttctttaa agcgtgcttc agcctcaaga ttgccagcat      2160
     ttttatcagg atgatatacc agagctaatt tacgataagc tttcttaatt tcaatatcgg      2220
     ttgcttcctt ggaaacacct aaaatcttgt agtgatcttt acgcttcgac tttttcaatt      2280
     ctagctgaag ccggcgtaat tcttgacgca agttagcatc gctcgcatct agttctatag      2340
     ctgactgcac gtctctaact gcctcttccc acttttcaag agcttcgtga gccttagcgc      2400
     gaacttttaa accttttaaa taagatgaat ctattgccaa agcattgtca ctgtcactca      2460
     aggcttcctc cggtcgtttt aagcgtaata acacagtagc tctattcatg tacaacttgg      2520
     cgacagtttc tttattatca ggatcaattt gcaaagcctc agaatatttt tcgtaagcat      2580
     cttggtaatt accttgacgg aacaaatcat ttccttgatt tttggtgttc tcgagtttac      2640
     gaacttgctt gaataatgtt ttggccgtag tgcaatcagg atctaatttc aatgcttctt      2700
     gaaaatgggt aatagccttc gcattctcac ccgaataata cattacttta ccacggagga      2760
     ctaaagcttc tacgttctta gggttaagtc gtaaaacatc gtgtgcaatt ttttgagcac      2820
     gatccatatc gttctgaaaa atatatacct gcgctttcaa atacatccac gacattgggg      2880
     gttgagtagt actatcaata cgacgctgaa ggcgatcaag agcattaaga gctaatccag      2940
     cttgcttatt tttcaaatac acctctgcct catttaaaat tgatagacct tcgtaagcct      3000
     gacgaatacg agattgtgtt tttggaacgt ctggcttaat acggtcggac tgtttcgcgt      3060
     cacataaagc caattcaaac tcaccaatct gcatataagt agcggcacga ttggaataat      3120
     aaatcgccaa cgctgaatct gatcctaaat caatggcttc tgtataggct ttgatagcct      3180
     ctgcatattt cttttcttta tagaaagcgt ttcctatagc cttttgcttt tcagctagct      3240
     cagcaggctc ttgttggctc tctgtacctg cattcatgtg tgtggtttcg acttcagtca      3300
     ttttgatcga attaatttaa atatttaaaa aatttaaatt ttatttaaaa tgacagaaag      3360
     ttcaggaacg ctttccaatc gccgaagcgt aacagatcaa aaagtcagtg gtaggtaaat      3420
     agatacgacc aaactattaa attttagtat cactaataag gaacactgct gtagctcctt      3480
     aagcatgtcc ccgatatttg tccaattcgt gaaagtaagt ctaaaatgtt ctttgaataa      3540
     tgtaattgtg aaagatagaa tataaataaa aaaatgcaag gaactctcac caagttttta      3600
     aacgatagtt gtgttttctg aaatatcata ggtatgttta cctaaactac ttaagttaaa      3660
     actattttct atttttgcga ccgtgtattc tatatgctaa taaatagcgg attcatgact      3720
     taaaaatttt tattagaaat ttggataaaa gtaaaaaaaa tattgcaagt atttaataaa      3780
     atttatttat ttatgttcga gtaagacaag tcattgttgt cctatgctaa atgttattaa      3840
     aattatcatg tctagtcaat tcatcatgga gaataatatc taatccagat gatcttattt      3900
     tgttaataag ctcattctcc ttgggtttgt tattttgcat tacgtccttt ttcaatcgag      3960
     taagatactc attaaatctt tcaacttcgt cttccaaaat tgagtgtaac ctgagagatt      4020
     gcaatgactg caaagcaaga tcgtacttag acttgtcaat aagattttta attacttttt      4080
     ccatttctgt caaagcatcc tctagtccaa aagggttttt caaaacttca gtgaaagtgc      4140
     ctactgggtc tttttcacta acgtgaagga ctaataattt ttctccttcc tgttcatcga      4200
     gaccagaatt tagtagttct tctatttgtt cctctgatat tggggcgcct gtgtcgaagg      4260
     ctgtttcttg agaagaatat tttggtttga cggggacgtt cactgtaagt ttttccttaa      4320
     tcaacttcaa gtccaaaatg caattatcaa gtaaactttt tggaggattg gtgtaacgtg      4380
     ttaagtaaat atttggttga ggaagatcgc cttctggtga atttgcataa taactgatag      4440
     cttgttgaag tctatgtggt atcatactaa aggtattttc gggctcaaaa ggaggattga      4500
     acccacaatc agaggaatct aaatccatat tatcgatata attacttacg gcaaaatcaa      4560
     tttgtcgcat atcctcttca tttgacagtt tctcgaactc tgagaaagaa taaggccgaa      4620
     catcttcagc gaatggaagt tgtatatcaa ccaagtaatg tcttttaaac tccacgtaag      4680
     gcatcaagac cagcaaaact ggtacgccct tatctttaga aacaaacctt gcgagcgcat      4740
     atcggtgttc acgttcaagg gattgaacaa aggcagaaaa atttaatttg ctttcgaagt      4800
     catcttttgg aacgattata ttagtatcac taatggtata ataaattgga agactagatt      4860
     taggaataaa tccaaggatt tcataaccgg gtattgtatc taaagccaat acgtcttcat      4920
     ctgatcggct gatcgggacg attgtcctac cataactata accgctttcc aagtcttctc      4980
     ttttaacctc aaaagaatcg tttgtttttg gatcacgaac catgtacgat cgaacagtag      5040
     acactgcatc agattccata cttttgtttt ccacatttga attttcgata ttaagacatt      5100
     cataattttt agacatatcg ttttcataaa aagcagatga tgttggcggt ttagttaaac      5160
     gagttctagg atatctttca acctgtatgc ttatagacgt atctttgctg tctctattac      5220
     caatactaaa tgtacctcta aagattgcga caggtctcac tttacgaacc caaggtttac      5280
     cgatgttgtt ataaatctgt tgaaatgtgc agtactgacc atgacaactc tcaacaaact      5340
     cttgaattcg aacttcgttt tcctttttct gagattcctt taaaggctca gaataattaa      5400
     tatcttcttg atcaaaatca actccataaa cacctagaaa aacatcatgc tgcagtagtt      5460
     gttcggcaat tccaatgtaa tcactaaagt cgataatccc cctagctgcc gtaagcacta      5520
     tcatcttctt cttccatttg ttctttttac aatgccgagc catcaaatca aaggacacaa      5580
     ctattgcaga tatcagatcg ccttgcatag tattgcttgg ttttaacgtt tgagaaacgg      5640
     attgtagctt tgaaaataag gcactagtta agaagttaat ggagcattta agagaaagct      5700
     tacgtttgta taggatacaa aacactgata ttccaatagg cttcctgctc agctaaatca      5760
     tttttcgtat ctaaacaccg taaaagttag aagtagtgta cctttaaaac attacaatag      5820
     aataccatcg catttgtaac caacgattcc aactacgtct gtcttcctat ttgctaaaaa      5880
     ctgagtatgt gtcaataggg tgtcgataat gttgagcaaa ataccttatg agacaattcg      5940
     tcgtgaaaat acgacaaagt ccattcgaga tcagaatgag acctgccatg gtgacaggtc      6000
     cccatatctt tgcccaagtc aagtacaaaa acagtacatt ccttatcact catacgaatt      6060
     gttaaggaat acagatttgg tggaggtcaa agcaaggtga gatttgttgt agaacattgg      6120
     ggcctccgat gctttcaaca gttagatatc aattacacgg tcattttaaa tgattcaggt      6180
     attttcttcg cggtatgaat atactacatt aacagtaagt ccagcagcat atgtgcaaat      6240
     gcacatgtga ctgaaatgta aataacccaa aacattgtat ataaattagt caattcattt      6300
     ttataactta aatcagaaac tcttgagaat tgaattggag ctattaaagt tgctaaggtt      6360
     ttacgcacat tagaaatttt gcatagcgat gcttttactt tcaattcaca cattaattta      6420
     caaagccgtg aactcatatc tcaagatgtc aataattagt taacattcag tttaactatt      6480
     catgttagat cttattagtt ttgtactagg cgattaaaac accgagctgc cagatgcata      6540
     tcgctcacaa atctttcgta ctacacgcaa attaccagaa aacgatacca cccccttgag      6600
     gtataatgtt taaggtgata tttggttttc tgttgtgaaa aatatattaa aaaacacaca      6660
     tatgtacttc aattatcgaa catacacatt tatactttgt tttaaaacgc caaaatggta      6720
     cgcttaactc ctcgattagt agccattttc cttgttgaaa aaacaacatc aggagctaat      6780
     ttcgtctttc actggccgct acaacctcaa gtacgtctac aagccactca tcataataat      6840
     gattcagcgg agtctgcaat cgggatgctc gaccttgatg acagcgatga tgatgagaat      6900
     aataggttta ctgaagtagc tgacgataca catgtacttg gttatgaaaa aggctttctc      6960
     gcaaatatgc taagtcctcg tattgaactt tgcaatcaaa aatttgaaat ttgggtggat      7020
     ggtcttactt ttttgggatg tcctgttcat attggtccga acggtgagtg ggctaaacga      7080
     aggaaaccac gaactactgt tgagtctaat gcttcttcga gccatttggt atcaaagccc      7140
     gaatcttcac acccttcgac aggaagtttt gaagtaaaat catcttcatc aaaatcgaga      7200
     tcttcaatgt ctttatttca tgtcgtcttt gtattaaatg tgcctacagc taccgtatat      7260
     cgccctactg taaacacgat gtatgatcat atagtagtca agttagttac tggacttaaa      7320
     tatgaacaag caaaacggaa ttatgttgaa aatgagtgta tacacatctt aaaactgact      7380
     gaaaaatatt caagccaaaa cgtcccattc gatgtgtatg ccgctcaaat ccctcatcac      7440
     tcaaatcttg cttcggttct tgctactaca tatgaggctt taattaacat gcatacggct      7500
     tatttagaga taaatcaatc gattaactta agcttactct ggcctatgtc ggtttccacc      7560
     aacacacttg aaaattacga actgcaggtt agaccatcaa ctattttagc atctcaaacc      7620
     atcttctctg aagaacatcc ttcctctatt gaacctttcg ttgcccccta ttggactttg      7680
     ttgctcttaa aggatacaga cactataatg aaacgtgttc ctcttttaca aaattctctt      7740
     ctttcttctt tcattgccat agtaaaacct aacttaacgt aagttttgtc aagtctaaac      7800
     aaaatttatt attgctatta aatactaact tacaatattt caggttcaca gatatcgcta      7860
     atcgtctagg aatatcagta tcagaatgct ttattctagc aaaacacctt attcattgga      7920
     gaaaggctat cgctattcct cctttgttaa tccggaatac ttatgttaca tccccaactg      7980
     ctaatctgtt taatttggag gaggagtcaa agctttttaa aaaggaattt ccgagccttc      8040
     cctcactgtc aacattttta gctattttgt cgtttaaacc gcgaccattt gcctccatta      8100
     ttccatcgaa agatcatgag ttagtttatt tggaaatgct tgcttggctg tgtcgaagaa      8160
     attgggttta tgaacagaat atctatatgt atattctcgt tccagaagaa attaagaaaa      8220
     aagcgattgc actaatagaa tctgatgagt cttctaaaaa tgacatgcag cttagaaagc      8280
     aacttgaaca agataatggc aaagagtcta ttatcattga tccgcactct gcctctttgc      8340
     ttgaacagaa atggattcaa attatagctt atgagagggg accagaaatg gctccattgt      8400
     ttacgtcaat tgtcaaatat ttaaatggta ggtttgcttt acaaactata tgggttgccg      8460
     aaggcttacc aaggaaacta atgcgaaata ttcttaatga gtataatgat tacatccttc      8520
     gatggcattc ttggtgaaac tacgaaagta tagcttggac tagcttatta atatttaatc      8580
     aaaatttaac acaccaaata tattaccatt gtacgatatt agtaaattaa ttattagaaa      8640
     acgtctttga aatcaagtca tgacaaatac ctaattatac aacctattcc atcaagcttt      8700
     ttttatattt tatagaagac cccatcttta aaaaaagtag attatacttt ttgataagca      8760
     ataattccca cattttcgtc taaaatttca agatcttctt caaggaacca tttaggcata      8820
     caataagtcc taaatggaat cagtaataaa ataataatag ggaaaccaat ggatgcttta      8880
     tcaacctgag taattgcaaa ggtagcacca aaacctatta attgcaaaat agtgtataac      8940
     caaactacgc gttttgagct acagtggttt aaagtatggt ttttagatac cacctttctg      9000
     tcacttaaca tccagattac gttttgagtg ataccgttgc caaatattgc tgaaaacccc      9060
     atcacctaaa attcagttag caaaatataa tcttcccttc aaaaaaaaaa aaaaataccc      9120
     aaaataatcc tgctaaaaca cattgaggaa tttgatgtaa caccagtaaa agtggaccag      9180
     tcatggtgcc aacagtcatc aatccctgaa tgaaattact agctcgttgt tcaacaactc      9240
     gatctataac ttctttatgc gttttttcaa tttcgtcttc atcataatca acccttttaa      9300
     cacaaagtgc tgcagtatgc atgggagcct gtggaataag cccatttgga gcaggaatac      9360
     ctaaaatacc actcactcca gtcgttatac caagaagaaa aaaatcccaa tgaaatccag      9420
     caggtttggt taatggaaac gaaggatctt gtgccattac agactactaa tgttaaaaaa      9480
     aggaaattaa acaatacata cagaaacgtt atgatcaaaa tagaatagga tagtgagaac      9540
     aatagaaaaa ggaattgcca ggaaaacatc cccaacgggt attttccaaa attttataaa      9600
     ccagcttcta gataacgtgg gttcaaaagc ttttgttgta ggaagtttcg ctaaagaaac      9660
     ttcccgcatt ttcccaatgt gctgaaaccc actgaaaaaa atgatggatg caacaagtcc      9720
     gtaatcaaga agtagaatac gtactttgta actgaataaa gaagattttc ctactgtatc      9780
     acaaagccat cccaccatta aaaataataa agcaatagta attgacagaa atgtatttgt      9840
     aagcccatac tttaattggt cacaaagaac ttgaacgcct ttttccaaat aaataaacgc      9900
     aacatatagg ccaaaaattt cacagctgaa ttttgtgcta cagttttcaa ttagctggat      9960
     atcacaagaa cataaaagca aaaagcgaac ttacatatgc tttacaaaat aaaccccatt     10020
     tgctatagca atgatgaagt gaaaaatcat tgaccaaaga caaatccagc aaaggaaagg     10080
     gaaatatggt gttcctctat catgcattat atcgtaaaca gtataattaa agactgtaat     10140
     aggccctgta accccgacga tgcacaaagg ctgcgaagaa agcaacgcga aaacaactga     10200
     acctaaaacg ctggcaagta aaacctcatt caccccaaaa ctgttatttg tttttgcaaa     10260
     catatctaag gcaaatgcta attctgggag taagctagca agtttagaaa aagcacgata     10320
     aaatgtcaat tgtgataaat gtatatttga aacgcacata ctttgaaaaa taaatattta     10380
     aacaagcagg aagtactcga taatgacatg catcaatcca gtcagatttg taataaggta     10440
     atcgcttttt tacatcatta acaatctctg acccaaaaat gtaattaaac ttcttatcct     10500
     ttttattcat atgattagag attatttaaa agaaagaaac gaattgggta tggcagattt     10560
     gcttttataa tgttggttag ttatatcata aaggccattg ggttctaata taccgtggta     10620
     tccacaaatt acggtaacgg tctaggaaga ttgatgcttt gtaaacaatt acctgtactt     10680
     aagaatattt agaatcaaaa ttaataggga gaaatattag tccataaaaa atatttttcc     10740
     acaatgtcgc aatgtccaca ttctttgcat tcttgttata aaatctattt catcgtcaca     10800
     tttgatagtt aatgtggtca ataaaaccgc aacctccttt aagtaaacaa aatttaaata     10860
     ttattatccg tatatatata taccttaaac cactaaaaca accttgaact tcaaaacttt     10920
     tatactactt ttccgtagat aaagtattct tcgctttctt tttgcgtcca gaatttttta     10980
     atttattaga aataccattg gccatcagcc ttttctcgtt tcgcttctgt ctcctttcac     11040
     caaatcccct atcgatcatc tcaagagaag cctggcgttt agcgtccgta acttccttga     11100
     tgtattcaag catcttattc tctgacacgt gttcatattc agaaagctta gttcctactc     11160
     gatcctcaat agcatggact aaatcaacat ctctctccgt tacaatggaa atggactcgc     11220
     cactgcgtcc agcacgagct gtacgaccta ctcggtgaat atagtcgtct gggtcacgag     11280
     gaaggtcgaa gttaattact agttgcacag aaggaatatc caaacctctg cttgcaacgt     11340
     cagtggctac caaaattttt gcagcttccg cacgaaaccg tccaagtgaa ttgatccttt     11400
     cacgttgtac catttctgaa tgaagttcgg tgacacgaag ctcgagcaat cgaagaatag     11460
     aatatatcaa ttcagcagtg cgagtccgat ttacaaagat aattgcagac tttttagcgt     11520
     tctcaggaat cgttaacaaa tgcaccaaat aagcttctcg tacttgtgag gaaacaaata     11580
     tgtaactttg ctgcaaagta gaaggtacgg aaatgttatc agtttcaact tcgtataacc     11640
     aaaggggagg cttattattt ttctgtggct gatatttgag ctgacgaata gcatcagtaa     11700
     cagttgcagt aaacaaaagc gtttgacgat cttcagaggc tggaagaaca gaaaagcaat     11760
     catccaagtc atcagcaaag gtaggagaca acaaacggtc ggcttcgtcc attaccaaaa     11820
     attttattcg acgtagtccg gctatcgttt cttcaccatt acttctaatc aagtcagcta     11880
     ggcgaccagg agtagctaca acaacatggg gccgtttcga taaatcaata gattgtcgta     11940
     tcatatccat gcctccaacg atgagcgcat gctttaaatt aagattagca cctaaagcag     12000
     caaattgttc atcaatctgt attgcaagtt ctctgttcga gttagctaat tgtagtagaa     12060
     tagttaacat ttatactaat ttaaatttta agaaaaagta caataatgtt atattttata     12120
     cctggttggt gtcaaaataa gagcaaatat tcctgatgga tccttagacc atttttcaat     12180
     aataggcaaa gcaaaagcag cagttttacc agaacctgtt ttagcacctc caatacaatt     12240
     acgtcctata aatttttatt tgttaggcac attttacact taattttact ttattaattt     12300
     ttgtaagcat accttctaaa atctgagcaa ttactccttc ctgaatatct gtaggttcat     12360
     atattgcaag tgcttttagc gtatcgataa gccatggcga tattcctaaa tcagagaatg     12420
     attttcttgt atgttctgac atgttttctc cccgatgtaa gggttttatt taaattaaat     12480
     ataatggtta ctgtactgtc aaaccaaact attgggattc aacttgttgc ccttactgca     12540
     aaattaacac gctacgctac attacgctgc tttagacatt attgctgatg cgacattttt     12600
     caatgacttt taggtcaaca tacacagata aaatcttcat atggttaaca taaagttttt     12660
     attgttctct aaaataagta cagatagaac tcaaactaat ttcttcagtt tgcttgtaag     12720
     ttatttagtg ctttttcggt aaaccaacgt gcaaaacaca atatttgaac tttacgtagt     12780
     taatcgtgtt cttataatag ttaacggatt gtatgtagtt attataagcc atagaaaatc     12840
     atgcaatgat aaatatattc ttttatgttt tccttgaaca aaattaatta taattttaga     12900
     ggtagacatt tatagtaaat aaaagaagaa agctcacagg atatgatagt ctcataatta     12960
     cattaactta tactcgtaat gaacaattcc cgaagtcgtt ttaacaaagg tctcactaat     13020
     tctaaaataa cgtatctaca tagctaagtc cataagttat ttagtgaagt cctaatttag     13080
     aaatgtaggt tatactaata atggtcaatc gtatttagta tagcttccga aaactatacg     13140
     atttcttcta atagaggcct cggttgtttg tttgcgagga attaactctt ccatcaaagt     13200
     ttccgtttat agtgctatcc tctaattttc taattcagga agcaaaaact tcaaaaaagt     13260
     ttataattgg taggtttatt tagcgggaag accatacgtt agaatttact ttccttgcgt     13320
     ttttggaaaa gaagaataaa aattgaagtt tgttaaaaat acaaacaaac ttttggactt     13380
     ggtatcagtc atctcttgtc actctttcta caaattgaaa aaatatcgaa gaaagcgccc     13440
     atgcctctat gtccaaaaaa cctgtcttga acttagatac cagtaatggg ttctctgaag     13500
     aatatataag tcatcctgaa cgtaatgaca atcaaggaat tgtcgagatt acagacctgg     13560
     tgttttctag cgagtcgaaa ttaactcagc gaaaggagag ccgggatagt aaaacatttg     13620
     ttccttcctt tctggaagaa cttgatgatg atcacctaca tgaattggtt acaaatggag     13680
     gtattttgta catgaacagt ctaggtgaag gtgttagtgg ctctgtaagg aaatgcagaa     13740
     ttcgtgggac tcagatgatt ttcgctatga aaactgtatt agctgctccg aataccgctt     13800
     tacaaaagca actccttcga gagttaaaaa tcaacagaag ttgtacctct ccttacatcg     13860
     ttaaatatta tggcgcttgc tacaataacg cagagtgtca gttaaacata gctatggaat     13920
     attgcggagc aggatctctc gacgcgatat acaaacgcgt acgcagtcaa ggtggacgca     13980
     ctggagaacg accattgggc aagattgcat tcggtgtcct tagcggttta agctatttac     14040
     atgacaggaa aataatacac cgtgatatta agccatcaaa tatccttctg acgtcaaaag     14100
     gtcaagtgaa gttatgcgat tttggtgtat ctggagaatt ggttaactct ctcgctggca     14160
     cattcactgg aacttcgtat tacatggcgc ctgaacgaat ttctggggga tcttatacta     14220
     tatcgtcaga tatatggtct ttgggtttaa cattgatgga ggtcgcatta aaccggtttc     14280
     cattccctcc cgagggtagc cccccaccaa tgcctattga attgctctcg tatataataa     14340
     atatgccacc tcccctttta cctcaagaac ccggtattaa atggtcgaaa tcctttcaac     14400
     attttctatg cgtgtgtctg gataaagaca aaactcgtcg tcctggaccc caaaaaatgc     14460
     ttacccatcc ttgggttaaa gcgtttgaga gaattcatgt ggacatggaa gagttccttc     14520
     gtcaagtctg gtctgattag aagaaatagt gtcatatgtt agcactgtaa gttgataaat     14580
     tctgtttgaa aattcttatg ctaaatttct ttacattgga gaatgcataa tctgattaat     14640
     ggcaaaatat tatgagtcta actgtcttcc agttcgcttg ttgtatgaaa taaataggaa     14700
     agtcataata atatatactt tttattaatt gctaacggtt tttctaattt tctttataca     14760
     aatacctcct ttatagtaat tttatgggtt taacattttt aacagaaata attttggctt     14820
     gattatgcat actcaaatcg tagcgagaaa tgatagattt acgccttgct agctttttaa     14880
     caaaaatagg caaaataggc gttatatggc aacttaaaaa acgaaagaat tcgtatattt     14940
     aattatccac aattaaggac tatttctttt cgttctctta taacgtgagg caatgattcg     15000
     ttttttttct agtctacgca cgtaagttgg tggtgtaact acaccaaact tcccagggta     15060
     tacatgtcct taactctttc aatgaattaa ttgcttttca ctacaccgtt ctatctttat     15120
     ttttaagttt aatttgtata cgttgtctgc ctaataaaaa ttatttaaaa aaaatgactg     15180
     aaaaaactgc tagtcattat tggaatgaag aaacctctat attgaagctt cgtcgcaaag     15240
     atatacttct gtttgaaata tatgccacta cacttcttct aggtagcatt tatagcattt     15300
     atgttgacaa atggtcgatt acctcttact ttggaaactc gaaaaatttg attaatttga     15360
     tttttgtaaa aagaggctgg ttctggactt ctttagtata tttttatcat gcttgggatc     15420
     aaaagagaaa caaaattgac ttcaagttta tttcaaggta tatagtggcc actctatggt     15480
     ggatgtttgt aacccaatgg tttataggac ctggcctgat tgatagaacc tttgcattat     15540
     ctggcggaag ttgcaaaaac tttgatggtg attcatctgt gttcattcca cttaccgcct     15600
     ccacttgcaa gggattaaac ggatcttggt ctggtggtca tgatctctcg ggccatgttt     15660
     tcttgttaac tcactcgagc ttgtttatgt tgtctgaaaa cttttcattt attttgaata     15720
     atggaataaa agctacatct actaaagtac tttttggtct tcttggactt tggtggtgga     15780
     tgttatttgt tactgcatcc ttttaccata ctacttttga aaaatgtacc gggtttttct     15840
     ctggtatttt agaatggtct attgtttacg tgttctcttc aagaatgcca gcggtcgctg     15900
     atcttttagg atcctccgat tactagcctt taccaccatt tgtccttaaa ctatgcttct     15960
     aaatgattgt tttatatagt gcaacacttg tgacatagca tatccttcct tctctaaact     16020
     tatttgttta tgaccctttt atctctctgt cgattattac gatagtgcca tcatgataaa     16080
     aaaaatcttt tcattattta ccaaaactaa gtatatttta gagagtattt tacttgggaa     16140
     aaatactcgt caattgtttt gagtgaaaat gcgttcttcc atatatattt gatagccgta     16200
     aagtttcttc tttatcaagc ttgcatatta tagtgactat tatttattcc tttttttttt     16260
     ttgatacaaa tatgcataaa tgttttttat tatggtatct aagttagtaa tgtaaatcaa     16320
     ctcgctaata ttatccattc agcaaattat aatgtatttt aatttgtcaa caatatactt     16380
     gtaatacgtt tagtaaatct atagtaatta atagagacaa tgctaagaag ttggttgatt     16440
     tcattacggt cggtgcccat aataaatgac taatgcttcg gaaggttgtc actacccaca     16500
     acacacaagt ccaaggcatc tatattatcc ttcctttagg ctattttttg ttgacaggat     16560
     tagtaacggg tttattgagc tgaaaaaaaa gtgacaactg tgttcttatt ccttttaatt     16620
     accatttttg ctgacgtgaa acattggaat ttcttcaatt tcataacgct ttttggaggt     16680
     tgcccaaatc catgtccgga ggtaataata aatttttatt ttaatacaac cttataactt     16740
     ttcgtctcta ttcgttttgg tctcaattac tgaattgaac gattaattac tgctttcttg     16800
     aattttttaa ttctagaatc cacctttact cgtcatatac gaaggatatt tttcttaaaa     16860
     caatcattta cgtttatctc tttcgatatt gagggtttta tatattatac ttgcccttac     16920
     acgctcaatt caagttattg taccctgcga cttatttcca tataatattc cttatgcgaa     16980
     atcccttttt gacgtttagg gcacctacta ggaaaacagg agattacctg gtttctaaat     17040
     tcgtaaagaa ggataatttt tcttctttgc gtttggcaag ggcttatact ttttctacac     17100
     gttccacagc tgtttcacaa ttttctcttc tctcactttc tcagagatct tttcagtccc     17160
     ttaaaataaa taaaggaata ccggaaaaac ataaaatccc tctcatttca tctaaacaat     17220
     ttagcgtaac ctcaaaaaga tcgcaaaatg ggtcttcagg atccaattct gatgctaatg     17280
     gtaggaaaaa tggccagaaa aatgatgatt caaaaaagaa gggattgaat ggcaatgatc     17340
     cgaaaaaagt ttttgaaata gccttaaatg gcaacactat tttaggtgga attttagttg     17400
     cctatatcct ttacaatgtt ctctcgccta atgcaaatat gcaagaaatt acttggcaag     17460
     attttcgaca acagttttta gacaagggtt tagttgaacg gctagttgtt gttaaccgca     17520
     atatggttag agttattttg agaggcggtg tagcttcagg ttcagggcag tactattttt     17580
     caattggttc catcgactct ttcgatcgaa aactagagga tgcacaacgt caactgggta     17640
     ttccaccttc tgaatttgtc cctgtcgctt atcatgacga agtctctgtt cttgctactt     17700
     tattgtcttt tgctcccacc ttactgatca ttggaagtgt catttattta tcgcgacggg     17760
     cttcgggtgc cgcaggaggt ggtcaaggtg gcatttttgg aattggtaag agccgagcga     17820
     agatgtttaa tcatgaaact gatatcaaaa taaaatttgc tgatgtcgct ggcgttgacg     17880
     aggctaaaga agagattatg gaattcgtca aatttttaaa aaatcccaag ttttatgaaa     17940
     ggttgggggc taaaattcct cgtggtgcca ttctttctgg tcctcctggt accggtaaaa     18000
     ctcttcttgc taaagccacc gctggtgaag ctaacgtccc ttttttaagt gtgtcaggtt     18060
     ctgagtttct tgaaatgttt gttggtgttg gaccttcccg cgtaagagat ctttttgcta     18120
     ctgctcgcaa gaacgctcct tgtattattt tcatagatga aattgatgca attggtaaag     18180
     caagaggacg tggaggacaa tttggttcca atgatgaacg cgaaagcact cttaatcagc     18240
     tattagttga aatggacggt tttacgtcta gcgaacatat cgtcgtattc gctggtacta     18300
     atcgaccaga cgtattggac ccggcacttc tacgtcctgg tcgattcgat cgtcaaatta     18360
     cgattgatcg tcctgatatt ggcggtcgtg aacaaatatt taaggtccac cttaagcata     18420
     ttaaggcagc cgataacatc gacttaattg ccaagcgtct tgccgtccta acttctggtt     18480
     ttacaggagc tgatataatg aatgtatgta atgaaggagc gttaattgca gcacgatcaa     18540
     atagtaatga agtccaaatg gtacattttg agcaagctat tgaaagagtc acggcaggtt     18600
     tggaaaagaa gagtagggta ctaagtcctg aagaaaaaaa caccgttgct catcatgaag     18660
     ctggacatgc ggtagctggt tggtttatgg agtacgtcga tccactattg aaggtctcaa     18720
     tcattcctag agctcaagcc cttggctatg ctagttattt acccaaagat cagtatctga     18780
     tgagtcgagg gcagatttta gatcaaatgg gaatggcttt ggctgggcgt gtttctgaag     18840
     aaatattttt tggaccagaa aagattactt cgggagcttc cgatgatttt caaaaagtaa     18900
     cgcgcatggc tcaagcgtat gtgacccaat atggtatgtc tccgactgtt ggtactatag     18960
     cttatcccat cgacactcgg gaaactgttc aaaaaccatt ttctgaggct acagctcaaa     19020
     tgattgatga agaaattcga aagcttgtaa agcatgcata cgaaagaact aagaaacttt     19080
     tgctagaaca taagcaaggc ttagaaaata ttgctcaacg tctattacag aaagaagtca     19140
     tcacttataa cgaagttgag acgattcttg gaccaaggcc atatgcatac aaacatttaa     19200
     atatttctga acttatgcgt cagtctgagt ataaaaatga tcacgatcct cgaaatccac     19260
     caatcccccc atctcctcaa caaccttctg cctaatttgt caatttactg aatttaaata     19320
     aagcgttatg aatgaaaata gttactttca tggatctcat gatcaaagta tttgtcaatt     19380
     gaatatcata tagctatttt atctattttt tctatttaat attacagaag ctagataaat     19440
     atacttaaca tcaattcttc tgaactttaa aaggttaata gattattatt ttctaacaca     19500
     aaatagctaa tatcgtaaca aacaaacttg tgtttagttt cgacctttag accagcatgt     19560
     catagggagc gtgatactca acagttacac gtttgacact aaccactgta ctttcttaca     19620
     agtccatatt ttatgatgga tctgattatt tcaacaattt tattaagctt atttattcat     19680
     ttcttcgata aatttgcaaa aaaaaggact attgatgggg taatttaaca tatatacttg     19740
     ttgtaaagaa aactaataat gtgaaaggct tatcgaattt acgttagtgt ttctaataat     19800
     aaagatttaa agaagaacaa agaaatttta gagcagctgc ttactgttaa gaaagagcta     19860
     aacgctacta gcagtcaaga tcagtttgct aaatgggccc gtctgaatag aaagtatgaa     19920
     caactcagtc aagagtggga aaaacaatca gccaatgtta aaattttcca agatactttc     19980
     aagcgggttt taagcctttt tctttggatt ttaacccgtg gattccggtt ttatattcaa     20040
     ttcaaagagt ccaaaacacc tgtctttttc ctccctgcat tcttgcttcc ttcttgggct     20100
     ctatgggtgc tatctcttcc acgatcaatc tacggtatgt tgtttttaat gaaaattctg     20160
     aaaatctttt ttttattttt attttcattt atcacaatgg cagctgaaat actaacatgg     20220
     catgtaggat cggttagctt aacagtttgg aattttgcgg ttcaaaaaac tatttccggg     20280
     atattttgat ctccaaatca tcaaagacgg tgactaattt taatatttta tcatttagtt     20340
     taattaacta aagggaaaaa gatgccatat gtattttcag taaagtcatt ttataaatgc     20400
     gttttctact tccttttctc ataagaaaga atgccatgga aagcatagtt taccatgcac     20460
     gattaatatt atgttattcc ttcacaaatt gtacacttta tgtgctctac actggttttc     20520
     atctaaattg tcatcggatt tcttatttct atgcctacta attcatttgc ttaatttgac     20580
     gctttcatat ttctgatgct gtttataccg aaagtttgaa atggcaaata ggttatttat     20640
     tacacaggac atctagaaag ggaacgatgc agggttttgg aaaacatcat aaagttacta     20700
     caatgttaat taagaagggc acaaaattat gattaaaatt taagctgaac ttcgatctta     20760
     ccttttcctt ttatgcaaca tttccaaccg ttgtatgttg tttttttaat cttcaaaatt     20820
     ttcagtacaa agataaattg tttcttgcat tgatttttcg agtaaattaa gttcatgata     20880
     aaaaatttgt aagactaaac gagacctatt ctctcgttta agagtcggat cgcacaatag     20940
     agtcttataa gcttcagcag tcaacccacc atttttgaaa cgactaatgc gcttttgaca     21000
     cagcatctgt agaaattcta tagcctt                                         21027
//