ID SPBC4F6 standard; DNA; FUN; 44778 BP. XX AC AL031534; XX SV AL031534.1 XX DT 08-SEP-1998 (Rel. 56, Created) DT 26-JAN-2000 (Rel. 62, Last updated, Version 3) XX DE S.pombe chromosome II cosmid c4F6. XX KW 2-isopropylmalate synthase; 60s ribosomal protein L25; KW adp-ribosylation factor 1; asparagine synthase; KW atp-dependent dead box rna helicase; beta transducin; Chaperonin; KW disulfide bond formation in the ER; G-beta; Helix-hairpin-helix motif; KW homology to longevity assurance protein; hsp78p; lim domain protein; KW Major facilitator superfamily protein; mating-type switching protein; KW protein kinase kin1; ribosomal processing, rna-binding nucleolar protein; KW ribosomal protein l33-like protein; rpl23a-2; KW small nuclear ribonucleoprotein f; swi10; trp-asp repeat; KW vacuolar protein sorting-associated protein; WD domain. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-44778 RA Gwilliam R., Rajandream M.A., Barrell B.G., Skelton J., Churcher C.M.; RT ; RL Submitted (07-SEP-1998) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk XX DR GOA; O42707; O42707. DR GOA; O59734; O59734. DR GOA; O59735; O59735. DR GOA; O59736; O59736. DR GOA; O74391; O74391. DR GOA; O74393; O74393. DR GOA; O74394; O74394. DR GOA; O74400; O74400. DR GOA; O74402; O74402. DR GOA; P22987; P22987. DR GOA; P36579; P36579. DR GOA; Q06182; Q06182. DR SPTREMBL; O42707; O42707. DR SPTREMBL; O74393; O74393. DR SPTREMBL; O74394; O74394. DR SPTREMBL; O74395; O74395. DR SPTREMBL; O74396; O74396. DR SPTREMBL; O74397; O74397. DR SPTREMBL; O74398; O74398. DR SPTREMBL; O74399; O74399. DR SPTREMBL; O74400; O74400. DR SPTREMBL; O74401; O74401. DR SPTREMBL; O74402; O74402. DR SPTREMBL; O74403; O74403. DR SWISS-PROT; O59734; RUXF_SCHPO. DR SWISS-PROT; O59735; YHXF_SCHPO. DR SWISS-PROT; O59736; LEU1_SCHPO. DR SWISS-PROT; O74391; R25B_SCHPO. DR SWISS-PROT; P22987; KIN1_SCHPO. DR SWISS-PROT; P36579; ARF1_SCHPO. DR SWISS-PROT; Q06182; SW10_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c4F6 overlaps cosmid SPBC3E7. XX FH Key Location/Qualifiers FH FT source 1..44778 FT /chromosome="II" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c4F6" FT /map="IIR" FT misc_feature 1..4768 FT /note="nominal overlap with cosmid SPBC3E7, EM:AL023534 S. FT pombe chromosome 2" FT CDS join(483..679,799..838) FT /db_xref="GOA:O59734" FT /db_xref="SWISS-PROT:O59734" FT /label=SPBC4F6.01 FT /note="SPBC4F6.01, len:78, SIMILARITY:Drosophila FT melanogaster, RUXF_DROME, small nuclear ribonucleoprotein FT f, (101 aa), fasta scores: opt: 364, E():8.5e-21, (71.4% FT identity in 70 aa)" FT /gene="SPBC4F6.01" FT /gene="SPBC3E7.14" FT /product="small nuclear ribonucleoprotein with Sm domain" FT /protein_id="CAA20721.1" FT /translation="MSFVPVNPKPFLQGLIGKPVLVRLKWGQEYKGTLQSVDSYMNLQL FT LNAEELVDGVKTGDLGEILIRCNNVLWVGESTV" FT misc_feature 510..680 FT /note="Match to PF01423 Sm, Sm protein Score 82.05" FT misc_feature 680..685 FT /note="gttagt, splice donor sequence" FT misc_feature 781..798 FT /note="ctaacgtgattttaatag, splice branch and acceptor" FT CDS join(complement(2711..2758),complement(1423..2529)) FT /db_xref="GOA:O59735" FT /db_xref="SWISS-PROT:O59735" FT /label=SPBC4F6.02c FT /note="SPBC4F6.02c, len:357, SIMILARITY:Saccharomyces FT cerevisiae, YKA8_YEAST, hypothetical 49.0 kd protein FT ufd4-cap1 intergenic region., (418 aa), fasta scores: opt: FT 1005, E():0, (45.5% identity in 330 aa)" FT /gene="SPBC4F6.02c" FT /product="homology to longevity assurance protein." FT /gene="SPBC3E7.15c" FT /protein_id="CAA20722.2" FT /translation="MGNNTSRRSQSQKFKNIPSISAGSFSTMPVQHRGRRRRSKSIVGR FT AAQNAVLRSKEKTWIVPLILLTLLVGWYFVNPNGYIKYGIFLSYPIPGTNPAQYGKGRL FT DIAFCLFYALFFTFCREFIMQEIIARIGRHFNIRAPAKLRRFEEQAYTCLYFTVMGSWG FT LYVMKQTPMWFFNTDAFWEEYPHFYHVGSFKAFYLIEAAYWIQQALVLILQLEKPRKDF FT KELVVHHIITLLLIGLSYYFHFTWIGLAVFITMDTSDIWLALSKCLNYVNTVIVYPIFV FT IFVFVWIYMRHYLNFKIMWAVWGTMRTINSFDLDWAAEQYKCWISRDVTLILLTALQLV FT NIYWLILILRIGYRAFTTNDTHDERSEDEDEEVSDEKSSAKKND" FT misc_feature complement(2530..2550) FT /note="ctaattgccttcttcatctag, splice branch and acceptor" FT misc_feature complement(2705..2710) FT /note="gtaagt, splice donor sequence" FT CDS complement(3385..5139) FT /db_xref="GOA:O59736" FT /db_xref="SWISS-PROT:O59736" FT /label=SPBC4F6.03c FT /note="SPBC4F6.03c, len:584, SIMILARITY:Saccharomyces FT cerevisiae, LEU1_YEAST, 2-isopropylmalate synthase, (619 FT aa), fasta scores: opt: 2056, E():0, (53.6% identity in 573 FT aa)" FT /gene="SPBC4F6.03c" FT /product="2-isopropylmalate synthase." FT /gene="SPBC3E7.16c" FT /protein_id="CAA20723.1" FT /translation="MKSTFEAAGRVAKGMLKDPSKKYKPFKGIQLPNRQWPNKVLTKAP FT RWLSTDLRDGNQALPDPMNGQEKLRYFKLLCSIGFKEIEVGFPSASQTDFAFVRHLIET FT PGLIPDDVTISALTPSREPLILRTIEALRGAKNATVHLYNACSPLFREVVFRNSKQETL FT DLAIKGSKIVTAATKNALESKETNWGFEYSPETFSDTEPDFALEVCEAVKGMWKPSAAQ FT PIIFNLPATVEMSTPNTYADLIEYFSTNISEREKVCVSLHPHNDRGTAVAAAELGQLAG FT GDRIEGCLFGNGERTGNVDLVTLAFNLYTQGVSPNLDFSKLDEIIRITEDCNKINVHPR FT HPYAGNLVFTAFSGSHQDAISKGLKAYDERKAVDPVWKVPYLPLDPHDVNSEYAAIIRV FT NSQSGKGGVAYLLKTNCGLDLPRALQVEFGSIVKDYSDTKGKELSIGEISDLFYTTYYL FT EFPGRFSVNDYTLSSNGPQSKCIKCVVDIKGEKKDTPSRVVIEGVGNGPLSALVDALRR FT QFNISFDIGQYSEHAIGSGNGVKAASYVEIIFNNTSFWGVGIDADVTSAGLKAVMSGVS FT RASRAFAK" FT misc_feature complement(4105..4989) FT /note="Match to PF00682 HMGL-like, HMGL-like Score 298.71" FT CDS join(5624..5721,5990..6317) FT /db_xref="GOA:O74391" FT /db_xref="SWISS-PROT:O74391" FT /label=rpl25b FT /note="SPBC4F6.04, len:141" FT /gene="rpl23a-2" FT /gene="SPBC4F6.04" FT /product="60s ribosomal protein l25." FT /gene="rpl25b" FT /protein_id="CAA20724.1" FT /translation="MSVGKAKGAQKTVQKGIHNKVARKVRTSTTFRRPKTLELARKPKY FT ARKSVPHASRLDEYKIIVNPINSESAMKKIEDDNTLVFHVHLKANKFTIKNAVKKLYSV FT DAVKINTLIRPNGTKKAFVKLSADADALDVANRIGFL" FT misc_feature 5722..5727 FT /note="gtaagt, splice donor sequence" FT intron 5722..5989 FT /note="intron confirmed by mRNA" FT misc_feature 5977..5989 FT /note="ctaattgttttag, splice branch and acceptor" FT misc_feature 6066..6305 FT /note="Match to PF00276 Ribosomal_L23, Ribosomal protein FT L23 Score 105.67" FT CDS complement(6811..7965) FT /db_xref="GOA:O42707" FT /db_xref="SPTREMBL:O42707" FT /label=SPBC4F6.05c FT /note="SPBC4F6.05c, len:384, SIMILARITY:Saccharomyces FT cerevisiae, EM47_YEAST, 47 kd endomembrane protein FT precursor, (445 aa), fasta scores: opt: 177, E():0.00056, FT (24.7% identity in 348 aa)" FT /gene="SPBC4F6.05c" FT /product="hypothetical protein; with coiled-coil region" FT /protein_id="CAA20725.1" FT /translation="MKFCSLFHVLSFCCTLAYAVPKSQFLQLHSLSNAIPVEWKWYGSV FT DEDSGYVYLTSKDSNEARSGSLWSTSVLRQVGWQLSTSFVAHVSENENTFFAIWYTSAV FT GSEGPVFGASDKWDGLLISQEIDQTGKIFVRGYLNDKSFELAQFTDPDLPPFAKCTIES FT SPEALNNIILKYGDQSGLELFVNDKPCFQVKDVILPQGYYFGVSSQSTSAKDLVALSNL FT NILPPDTSNNENLNPTSNTKQSVGDNTSPQTVIDTEGLNAIKADLAKLFNLVESQRQKM FT DSLHFALTNALERLNDISSTSQFPSERFNALEKLLHDSLSAQSSTADGTSKHLAEFEKE FT IKKAMGNAYSPYNLTNFMVFLLLGAIVSYGIMLVRRDRRRHKYL" FT CDS 9961..12636 FT /db_xref="GOA:P22987" FT /db_xref="SWISS-PROT:P22987" FT /label=kin1 FT /note="SPBC4F6.06, len:891" FT /gene="kin1" FT /gene="SPBC4F6.06" FT /product="protein kinase kin1" FT /protein_id="CAA20726.1" FT /translation="MEYRTNNVPVGNETKSAALNALPKIKISDSPNRHHNLVDAFMQSP FT SYSTQPKSAVEPLGLSFSPGYISPSSQSPHHGPVRSPSSRKPLPASPSRTRDHSLRVPV FT SGHSYSADEKPRERRKVIGNYVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDI FT TKAKAAASAEATKAAQSEKNKEIRTVREAALSTLLRHPYICEARDVYITNSHYYMVFEF FT VDGGQMLDYIISHGKLKEKQARKFVRQIGSALSYLHQNSVVHRDLKIENILISKTGDIK FT IIDFGLSNLYRRQSRLRTFCGSLYFAAPELLNAQPYIGPEVDVWSFGIVLYVLVCGKVP FT FDDQNMSALHAKIKKGTVEYPSYLSSDCKGLLSRMLVTDPLKRATLEEVLNHPWMIRNY FT EGPPASFAPERSPITLPLDPEIIREMNGFDFGPPEKIVRELTKVISSEAYQSLAKTGFY FT SGPNSADKKKSFFEFRIRHAAHDIENPILPSLSMNTDIYDAFHPLISIYYLVSERRVYE FT KGGNWNRIAKTPVSSVPSSPVQPTSYNRTLPPMPEVVAYKGDEESPRVSRNTSLARRKP FT LPDTESHSPSPSATSSIKKNPSSIFRRFSSRRKQNKSSTSTLQISAPLETSQSPPTPRT FT KPSHKPPVSYKNKLVTQSAIGRSTSVREGRYAGISSQMDSLNMDSTGPSASNMANAPPS FT VRNNRVLNPRGASLGHGRMSTSTTNRQKQILNETMGNPVDKNSTSPSKSTDKLDPIKPV FT FLKGLFSVSTTSTKSTESIQRDLIRVMGMLDIEYKEIKGGYACLYKPQGIRTPTKSTSV FT HTRRKPSYGSNSTTDSYGSVPDTVPLDDNGESPASNLAFEIYIVKVPILSLRGVSFHRI FT SGNSWQYKTLASRILNELKL" FT misc_feature 10333..11145 FT /note="Match to PF00069 pkinase, Eukaryotic protein kinase FT domain Score 353.28" FT CDS join(complement(14997..15152),complement(14105..14960), FT complement(13765..14053),complement(13082..13727)) FT /db_xref="GOA:O74393" FT /db_xref="SPTREMBL:O74393" FT /label=SPBC4F6.07c FT /note="SPBC4F6.07c, len:648, SIMILARITY:Mus musculus, FT Q61119, atp-dependent rna helicase, (479 aa), fasta scores: FT opt: 901, E():0, (37.1% identity in 437 aa)" FT /gene="SPBC4F6.07c" FT /product="atp-dependent, dead box, rna helicase" FT /protein_id="CAA20727.1" FT /translation="MPKKAALDELKWKEVKLPDHLDDFDGFMGLEEIEGVDIKYQPKGA FT MKEVIYELPEVHEKKDKKPEKRKKDQKEASEKKKKGKRTSPTIEMTSLGSKVTSKNYNE FT FSTLEEEDEHNSHGVDVSAWAHFSLSPEMLGSLSKAGFSKPMPIQSLVIPEASIGFDII FT GKADTGSGKTLAFGIPILEHCLRNVDAKYVQALVVAPTRELAHQICQHFELIKPSPNIR FT VMSITGGLAVQKQQRLLNKHPHVVVATPGRLWSVINENNLTGNFKKIKCLVLDEADRLL FT QKSHFEELSKLLEILGNPMHTQRQTFIFSATFDEGLQQRLKKNMKGNITEKYNSPMENM FT LKEVRFFGKPKFLDANPQSAVASRVLEGLIECAPAEKDLYLYYLIMRYPGKTMVFANGI FT EDIKRITPFLNELKVPSYPLHAQLDQKKRLQSLEKFKNNPKGVLVCTDVAARGIDIPSV FT THVIHYHVPHTADMYVHRSGRTARANEDGVSILMCGPKELSQLKRLCYRLKKKIETFIN FT FPVDMSILDILKTRVVLAHKIVNLTRKDGRVGREEAWLKSMAQELGVESSDDEDPDLPK FT KSESSKNKKQIAHLRSELAPLLHEKIRTGFSGRYLTSGLVNMAEKLANEEVHDNIIGMD FT SISALEVLQKRKK" FT misc_feature join(complement(13765..13844),complement(13577..13727)) FT /note="Match to PF00271 helicase_C, Helicases conserved FT C-terminal domain Score 95.64" FT misc_feature complement(13701..13946) FT /note="Pfam match to entry PF00271 helicase_C, Helicases co FT nserved C-terminal domain" FT misc_feature complement(13728..13739) FT /note="ctaactaacaag, splice branch and acceptor" FT misc_feature complement(13759..13764) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(13995..14738) FT /note="Pfam match to entry PF00270 DEAD, DEAD and DEAH box FT helicases" FT misc_feature complement(14054..14068) FT /note="ctaacgactgcatag, splice branch and acceptor" FT intron complement(14054..14104) FT /note="confirmed intron" FT misc_feature complement(14099..14104) FT /note="gtatgt, splice donor sequence" FT misc_feature complement(14121..14708) FT /note="Match to PF00270 DEAD, DEAD/DEAH box helicase Score FT 176.72" FT misc_feature complement(14961..14971) FT /note="ttaacaaacag, splice branch and acceptor" FT intron complement(14961..14996) FT /note="confirmed intron" FT misc_feature complement(14991..14996) FT /note="gtataa, splice donor sequence" FT CDS join(complement(16020..16042),complement(15867..15968), FT complement(15766..15808)) FT /db_xref="GOA:O74394" FT /db_xref="SPTREMBL:O74394" FT /label=SPBC4F6.08c FT /note="SPBC4F6.08c, len:55, SIMILARITY:Arabidopsis FT thaliana, AAF08581, putative 50s ribosomal protein l33., FT (58 aa), fasta scores: opt: 175, E():5.8e-09, (47.3% FT identity in 55 aa)" FT /gene="SPBC4F6.08c" FT /product="ribosomal protein l33-like protein; FT mitochondrial" FT /protein_id="CAA20728.1" FT /translation="MAKKNKARLLVKLLSTAGTGFFYVRSRPKAAPKLAFIKYDPKIHK FT RVLFEESKMK" FT misc_feature complement(15809..15827) FT /note="ctaatgaatgaacccatag, splice branch and acceptor" FT intron complement(15809..15866) FT /note="confirmed intron" FT misc_feature complement(15861..15866) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(15969..15986) FT /note="ttaacatttatttttcag, splice branch and acceptor" FT misc_feature complement(16014..16019) FT /note="gtaaga, splice donor sequence" FT misc_feature 16043..20315 FT /note="low complexity gene-free region" FT CDS 20316..22154 FT /db_xref="SPTREMBL:O74395" FT /label=SPBC4F6.09 FT /note="SPBC4F6.09, len:612, SIMILARITY:Saccharomyces FT cerevisiae, Q08299, chromosome xv reading frame orf FT yol158c., (606 aa), fasta scores: opt: 576, E():6.6e-28, FT (30.5% identity in 522 aa)" FT /gene="SPBC4F6.09" FT /product="MFS efflux transporter of unknown specificity" FT /protein_id="CAA20729.1" FT /translation="MRLKSFSTTLDTLRRRFNDSSSEEDKLEKNIQDETSIKEVSLQDA FT KQSDEKGVEEKVFNDESFSIDVAPKPEDELSGIVKARYLTEHSSRISFYICYFSIFLLF FT FAISFQAECYYSLTAYATSAFAGHSLLSTIAVANNIISAAIKPPLARLSDVFGRLEAFL FT FSLLLYLVGLILMAASTNVQTYAGGSVLYNAGYTGVELIMTIFMADTSSMANRSLVLGI FT SYLPFVVTIWIGPRVAQEFYMHSTWRWGIAVWTILIPACSIPFLAVYSYYQFRAWREGA FT LKGTLTINPVELFKKLDIIGLILMTAGLALVLLSISLASYDTGKWSDAKFIVMIIIGGL FT CLIAFVLYEIFVASFPALPFRLMREPTIGACCAMSFLFYITFYCWDNYYYSFLQVVHYT FT SITAAGYISYTYSFTSCATGFFLGILIRLTKRYKWYFVASIPVYILGQGLMIRYRGEQY FT NWGYQIMPQIIVGIGGGVIANLLTVAVQTVVSTENFAIVTALVSTVTPIGGAVGSAISG FT AIWNSVMPKRLEKNLPSDLKDQAYTIFESLTVQLSYTRGTDARNAIILSYSEVQKILTS FT VATGFAGAMIFPVWFVANPRLSTVKTHIFDSKESKV" FT CDS 22869..24482 FT /db_xref="SPTREMBL:O74396" FT /label=SPBC4F6.10 FT /note="SPBC4F6.10, len:537, SIMILARITY:Saccharomyces FT cerevisiae, VPS9_YEAST, vacuolar protein sorting-associated FT protein vps9., (451 aa), fasta scores: opt: 782, E():0, FT (34.4% identity in 427 aa)" FT /gene="SPBC4F6.10" FT /product="putative vacuolar protein sorting-associated FT protein" FT /protein_id="CAA20730.1" FT /translation="MDYPSFHEDPTKDESTVAEQRKGQSNEEKPLIDLNDSLDEQRNAY FT NEHCKNHDQQPSQQVRNMEDEANQYEQTDSSSDQEVMNEKQSLDKENRNDNIPHENNPG FT QQEINEPIFDFHMFLEQLRSSSAEPVAKYLKSFLSEFTKRRWTVNYQVKLIRDFLKFIN FT EKIEQYEPWASGSQAEIDNAKEGMEKLVLNRLYTSLFSPEIAKSGIPLSSEHSDDVEED FT RVLSEKMELFQWITEENLDIKKQKSSSKFFKLAADELRRINDYHAPRDKIICLLNCCKV FT IFSYLRNVVKEESADMFVPILIFVVLQARPAHLVSNIQYIQRFRSPEKLTGEVMYYLST FT LMGAMSFIETLDCSSLTITEEEFNAQIEKSIKKMEERKLSEKSESKTAVNENATYKDPV FT LSRGLSSSIDVSTGVALVNLPEELENMKYLQIDTPESKEYPRSTRPRALLIVALSQLIL FT EKDHAETQTSMLVLAIDLPIEYLVHIPRLLPILPSFMKSSQWMMDYNKMMTCERQQQRL FT LRQLKLKGYKLGKRLKQLRL" FT conflict 24208..24209 FT /note="c18A7 has sequence 4033 here- checking FT GCACAAGGCCGAGAGCCTCTTCTCATAGTGGCT" FT /citation=[1] FT CDS complement(24641..26287) FT /db_xref="SPTREMBL:O74397" FT /label=SPBC4F6.11c FT /note="SPBC4F6.11c, len:548, SIMILARITY:Caenorhabditis FT elegans., Q21555, m18.3 protein., (475 aa), fasta scores: FT opt: 332, E():1.1e-14, (28.4% identity in 451 aa)" FT /gene="SPBC4F6.11c" FT /product="putative asparagine synthase" FT /protein_id="CAA20731.1" FT /translation="MCGILFALAEDRDNLLESPSFSALRKRIRARGPDFFGKHKLNSGP FT WNLHFESSVLHLRGPSDHLTPQPHVDSFGNVLCWNGEIWQINHSDHHKFTLNRNENDGA FT KLFELLNNNPGDIEKILGSIQGPFAFVYYQVRTNTLWWGRDRLGRRSLLYSLRDSNFVL FT SSVGNSSDFREVEPGFHSVQVDLIPKINFSKSLMQLEKTNPLPPVDESFLMGSISSDTV FT DTLHTYLIKALQDRVLTIPKLCSSNLDCSHYSRVCVLYSGGVDCGVLARLMHDIVPNNE FT SIDLINVAFENPRFTETYRDRETGLLPDNFDAYDVCPDRQTGLQGWQELISVCPARKWN FT FVAINVPYTEVCEAQEIVKTLIYPNDSVMDLSIGLAFYFASQGRGVLLQNVDDIKLKHQ FT LPSYTIKAKVLISGLGADEQLGGYMRHLRAFERKGMAGLEEELQLDIDRIPHRNLGRDD FT RVMSNQGKEVRYPFLDERLMALFSKMKTTDKMRLDLVGGDKLILRELGRRLGCPLASQE FT KKRAIQFGSKAAKMTPGTGRTSGRKKLEVCI" FT CDS join(27305..27333,27390..28677) FT /db_xref="SPTREMBL:O74398" FT /label=SPBC4F6.12 FT /note="SPBC4F6.12, len:438, SIMILARITY:Homo sapiens, FT O60711, leupaxin., (386 aa), fasta scores: opt: 434, FT E():1.9e-17, (25.9% identity in 321 aa)" FT /gene="SPBC4F6.12" FT /product="lim domain protein; leupaxin like" FT /protein_id="CAA20732.1" FT /translation="MHSPIPELPRFERRLTGPRAAPSSPVSTNGSPLNNLVRSRLSDGA FT LNFTGGRIATPLPQPSLKTPESPLSKRNPTIKQNRVRFDLPDDELSRSNVSSPEKTLLT FT SASTSTFDSLKKELLPELPSLAYSDDDEFPSSPEELNSHVNYPDVRNVYDCHTGLQPLV FT DHDCIEDRQKTFASKQLPTLPLQKSSKLSNRRPALHSFHSAPANSLYPLPTPTSQLPSN FT LSSNNLFQSDSLKPSMVSSHTSTKPVLYRGNSEKSCHSCGGSLRAGRIISASGKKLHPQ FT CFKCDTCSQNLEHVGFYYREGKFYCHLDYHEQFSPRCKHCKTPIEDQAVHINNDWFHEN FT HHFCAGCSEVFNVNIPCIYRDDLYWCQTCYDNKYAVKCKKCRKPILGISVKGSDGEYHS FT QCWTCGACNALLGDEGYFMIENTPICRPCKAISVKFNLD" FT misc_feature 27334..27339 FT /note="gtaatc, splice donor sequence" FT misc_feature 27372..27389 FT /note="ctaacttcgtttttgtag, splice branch and acceptor" FT misc_feature 28076..28249 FT /note="Pfam match to entry PF00412 LIM, LIM domain containi FT ng proteins" FT misc_feature 28132..28305 FT /note="Match to PF00412 LIM, LIM domain containing proteins FT Score 66.75" FT misc_feature 28256..28429 FT /note="Pfam match to entry PF00412 LIM, LIM domain containi FT ng proteins, score 14.40, E-value 0.014" FT misc_feature 28312..28485 FT /note="Match to PF00412 LIM, LIM domain containing proteins FT Score 27.00" FT misc_feature 28436..28588 FT /note="Pfam match to entry PF00412 LIM, LIM domain containi FT ng proteins, score 24.10, E-value 2.5e-05" FT misc_feature 28492..28644 FT /note="Match to PF00412 LIM, LIM domain containing proteins FT Score 33.76" FT CDS complement(29217..31427) FT /db_xref="SPTREMBL:O74399" FT /label=SPBC4F6.13c FT /note="SPBC4F6.13c, len:736, SIMILARITY:Drosophila FT melanogaster, O96841, eg:52c10.1 protein., (784 aa), fasta FT scores: opt: 1319, E():0, (38.5% identity in 761 aa)" FT /gene="SPBC4F6.13c" FT /product="WD domain protein" FT /protein_id="CAA20733.1" FT /translation="MNRKRSRSKRANSNVGVEKDKEKEKSKGVSNVPNEVETESSSHEP FT SFKKDVDEEIPSLTAELSEEEEGEYSSESGRSTPELSPDDFEDADDEEEFEEIDAGYSS FT DSSTEDVAPGLYESPYDENLYINYDIDGKKITRPATPAALDSLIASIDKDKGWTGIVDP FT MTGKPVNLTTEELGLLKRLAQSEIPDENFDPYPDYDDFFTNTVRETPLSSAPEPKRRFA FT PSKHEQKRILQLAYAIRKGRILTSEQRAERERESQSNYADHDLWADDDQATVNQRKLDY FT APAPKLPPPSHEESYNPPEEYLKQSSDFPKKYKSLRVVPAYSNLIKEKFERCLDLYLAP FT RVRRTKLNIDPESLLPKLPTPSELRPFPTRCTNVFIGHKGRVRCLSVHVSGNWLASGGD FT DGVLRIWEVMTGRCVWKCSLDSFGNAHNIDSDEDAVNESLSHSTKSSIIQSLAWGPLSD FT SPVLAVAVDETVYFITPPIFSDEQIEASKELFTSAPYQESSAIWRRGAKQSLQLHGGIV FT HATVSTPSSIKSLSWHRRGDYLATSSPTSSSQAVLIHQLSRGASQSPFSKSKGSVQAVT FT FHPTMPYLLVATQRYVRIYNLVKQELVKTLLTGVKWVSSLSVHSSGDHVIIGSYDKRLC FT WFDLDFSSKPYKNLRYHSRALRDVSYHPSLPLFCSGSDDGDVQVFHGRVYSDLLANPLI FT VPLKILRNHKVVDNVGVLSTCWHPKEAWLFSAGAGGEIRMWT" FT misc_feature complement(29385..29474) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 21.30" FT misc_feature complement(30207..30320) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 42.15" FT misc_feature complement(30207..30323) FT /note="Pfam match to entry PF00400 G-beta, WD domain, G-bet FT a repeats, score 38.40, E-value 1.6e-07" FT CDS 31658..33682 FT /db_xref="GOA:O74400" FT /db_xref="SPTREMBL:O74400" FT /label=SPBC4F6.14 FT /note="SPBC4F6.14, len:674, SIMILARITY:Caenorhabditis FT elegans., O62325, r05h10.2 protein., (406 aa), fasta FT scores: opt: 358, E():4.6e-14, (26.7% identity in 378 aa)" FT /gene="SPBC4F6.14" FT /product="RNA binding ribonucleoprotein" FT /protein_id="CAA20734.1" FT /translation="MNSNSTLFVRNLAFQTKQDDLTNFFSDVGPIKHAVVVTNPETGEN FT RGYGFVTFSMLEDAQRAAKELKNKKLHGRILRLDFATPRKRSEVDTDQNKAVKKTIRQD FT NRPRLIIRNLPWSIKKPQHLEPHFSKFGKVREIKIPTKGGGRMCGFAFVWMKDRKAAEE FT AMNSLNGTEIDGRPIAVDWAVSKDAFEATTLKDASSEEENKEFVSDEGHSIVTEDASAD FT SESEEEVDGHSEGKELAGESEEEGSNVDDVEDSGDSSSDKNSINHEIRDNEGLEDTVFV FT RNLLFECTEQELYNHFRQFGPLAYAKLVKDPATDRSLGRGFIKFRYEKDCQNCLEMASQ FT LPTQEPTEAEKRFLPSVLVDEGIDTDSVSSRFLLHGRLLKVTSAVTRKEASDINQKSLQ FT ERKQKMGKGVDRRHLFLLNEGKIAADHPLFNSLSETDKTLRSQSIAQRKKLLEKNPTLH FT LSLNRLSIRNISRHIDPKILAMLGRQAIRGFMDDVSKGLRANITEEEENLDKGHRLKRG FT KSGGVLKQAKVETEKAGAGRSKGFGFMQFISHKYALMALRWLNGREITVKKIIDAEIEW FT ARKHKIPEPQLPNIDYNDRPRRLIVEFAIENIQVVKRRQEKEKSFRQKAKQLKQQEDED FT NLKRKRSESDVEDNEAKEKQAKVARIIQRKRMKRRSRKN" FT misc_feature 31676..31888 FT /note="Match to PF00076 rrm, RNA recognition motif. (a.k.a. FT RRM, RBD, or RNP domain) Score 86.34" FT misc_feature 31676..31891 FT /note="Pfam match to entry PF00076 rrm, RNA recognition mot FT if. (aka RRM, RBD, or RNP domain), score 83.30, E-value 5e- FT 21" FT misc_feature 31982..32197 FT /note="Match to PF00076 rrm, RNA recognition motif. (a.k.a. FT RRM, RBD, or RNP domain) Score 68.60" FT misc_feature 32492..32668 FT /note="Match to PF00076 rrm, RNA recognition motif. (a.k.a. FT RRM, RBD, or RNP domain) Score 62.69" FT misc_feature 32492..32704 FT /note="Pfam match to entry PF00076 rrm, RNA recognition mot FT if. (aka RRM, RBD, or RNP domain)" FT CDS join(complement(34785..34931),complement(34640..34657), FT complement(34511..34596),complement(33943..34450)) FT /db_xref="GOA:Q06182" FT /db_xref="SWISS-PROT:Q06182" FT /label=swi10 FT /note="SPBC4F6.15c, len:252" FT /gene="swi10" FT /gene="SPBC4F6.15c" FT /product="mating-type switching protein swi10." FT /protein_id="CAA20735.1" FT /translation="MSDIDDEEFEQLAVSALEEVEKKAGFAQQPTPQKVSRVTAHSILV FT NPRQKGNPLLPHVRNVPWEYTDIVPDFVMGTGICSLFLSLKYHHLHPEYIYSRISKLGK FT SYNLRILLILVDVENHQASIQELVKTSIVNQYTLILAWSSEEAARYLETYKAYENMSPA FT LIMEKPSTDYLSQVQSFLTSIRGINKSDSLSLLSKFGSLERALVASRDELEQLEGWGPT FT KVNRFLEAVQQPFMSHSTIKRPEAINLKQT" FT misc_feature complement(34012..34101) FT /note="Match to PF00633 HHH, Helix-hairpin-helix motif. FT Score 41.74" FT misc_feature complement(34242..34334) FT /note="Pfam match to entry PF00633 HHH, Helix-hairpin-helix FT motif., score 42.30, E-value 1.1e-08" FT misc_feature complement(34451..34469) FT /note="ctgacttacatcatgctag, splice branch and acceptor" FT misc_feature complement(34505..34510) FT /note="gtatgt, splice donor sequence" FT misc_feature complement(34634..34639) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(34658..34671) FT /note="ttaacttcttatag, splice branch and acceptor" FT misc_feature complement(34779..34784) FT /note="gtaaga, splice donor sequence" FT intron complement(35384..35550) FT /note="confirmed intron; in UTR of swi10 or SPBC4F6; spans FT snoRNA" FT snRNA complement(35441..35526) FT /note="putative snoRNA, sp-U18, complements: sp-25s-rRNA FT and modifies Am674. Yeast U18 homolog. (Todd Lowe)" FT CDS complement(35787..37190) FT /db_xref="SPTREMBL:O74401" FT /label=SPBC4F6.16c FT /note="SPBC4F6.16c, len:467, SIMILARITY:Homo sapiens, FT AAF06104, ero1l, (385 aa), fasta scores: opt: 502, FT E():1.2e-25, (32.5% identity in 391 aa)" FT /gene="SPBC4F6.16c" FT /product="yeast ero1 homolog; possibly required for protein FT disulfide bond formation in the ER" FT /protein_id="CAA20736.1" FT /translation="MIGITKLISIWNAIWNFLLLPEIIISQTDTSSTGIYQMQSKVRSL FT VPVLTERSDYFSYYRVNLYRSSCPLWENDNAMCSNQGCAVKSLNEIEIPKVWKKLSDFE FT PHSKKNDTKCNWKYNPDLDYCYLDNSTSPDEYVYVSLVQNPERFTGYAGDHSAAIWRSI FT YEQNCFVVDDDDNPSEQPKSNALFRPNQIPLNLFTENHDDTSLSPSVACLEKRMFNRII FT SGFHASISTHVCQNYYDVEEQRWTQNLDWWRAKVGSFPDRIENIFFNYALLHQALVQIA FT TQMKNITSDSSFTFCPTDKDVDWRTHTAFEQLVYHAYQDRHVINREQFFADEEAKRFKD FT SFRKHFRDISRIMDCVGCDKCRLWGKVQITGYGTALKLLLEPETQLSDLRPEEVVALVN FT TFDRISHSVEATFWFSLKAKTNDTLDAIKALIYKTYRSPSKEILAFFIDQTWYLFYALF FT FICNVPRVI" FT CDS complement(38028..40439) FT /db_xref="GOA:O74402" FT /db_xref="SPTREMBL:O74402" FT /label=SPBC4F6.17c FT /note="SPBC4F6.17c, len:803, SIMILARITY:Saccharomyces FT cerevisiae, Q12137, hsp78p., (811 aa), fasta scores: opt: FT 2930, E():0, (57.7% identity in 803 aa)" FT /gene="SPBC4F6.17c" FT /product="yeast Chaperonin hsp78 homolog" FT /protein_id="CAA20737.1" FT /translation="MNILPKSIPIRIQSLRRYQGSLKTSLRALSTRPIFEKRLLAETPF FT SIRPSNASVLIAKRSPKFGWKQVRFYAANPNGGNFRMDLGGGRKQGAALEEYGTDLTAL FT AKQGKLDPVIGREEEIQRTIQILSRRTKNNPALVGPAGVGKTAIMEGLASRIIRGEVPE FT SMKDKRVIVLDLGALISGAKFRGDFEERLKSVLSDLEGAEGKVILFVDEMHLLLGFGKA FT EGSIDASNLLKPALARGKLHCCGATTLEEYRKYIEKDAALARRFQAVMVNEPSVADTIS FT ILRGLKERYEVHHGVRITDDALVTAATYSARYITDRFLPDKAIDLVDEACSSLRLQQES FT KPDELRRLDRQIMTIQIELESLRKETDTTSVERREKLESKLTDLKEEQDKLSAAWEEER FT KLLDSIKKAKTELEQARIELERTQREGNYARASELQYAIIPELERSVPKEEKTLEEKKP FT SMVHDSVTSDDIAVVVSRATGIPTTNLMRGERDKLLNMEQTIGKKIIGQDEALKAIADA FT VRLSRAGLQNTNRPLASFLFLGPTGVGKTALTKALAEFLFDTDKAMIRFDMSEFQEKHT FT IARLIGSPPGYIGYEESGELTEAVRRKPYAVLLFDELEKAHHDITNLLLQVLDEGFLTD FT SQGRKVDFRSTLIVMTSNLGSDILVADPSTTVTPKSRDAVMDVVQKYYPPEFLNRIDDQ FT IVFNKLSEKNLEDIVNVRLDEVQQRLNDRRIILTVTEAARKWLAEKGYSPAYGARPLNR FT LIQKRILNTMAMKIIQGEIKSDENVVIDVLDGELEFKANKLEPQSTSHED" FT misc_feature complement(38100..39050) FT /note="Match to PF00495 clpA_B, Chaperonin clpA/B Score FT 635.20" FT misc_feature complement(38100..40160) FT /note="Pfam match to entry PF00495 clpA_B, Chaperonins clpA FT /B" FT CDS join(complement(42656..42706),complement(42096..42587)) FT /db_xref="GOA:P36579" FT /db_xref="SWISS-PROT:P36579" FT /label=arf1 FT /note="SPBC4F6.18c, len:180" FT /gene="arf1" FT /gene="SPBC4F6.18c" FT /product="adp-ribosylation factor 1." FT /protein_id="CAA20738.1" FT /translation="MGLSISKLFQSLFGKREMRILMVGLDAAGKTTILYKLKLGEIVTT FT IPTIGFNVETVEYRNISFTVWDVGGQDKIRPLWRHYFQNTQGIIFVVDSNDRERISEAH FT EELQRMLNEDELRDALLLVFANKQDLPNAMNAAEITDKLGLHSLRHRQWYIQATCATSG FT DGLYEGLEWLSTNLKNQ" FT misc_feature join(complement(42656..42703),complement(42099..42587)) FT /note="Match to PF00025 arf, ADP-ribosylation factor family FT Score 419.20" FT misc_feature complement(42167..42703) FT /note="Pfam match to entry PF00025 arf, ADP-ribosylation fa FT ctors (Arf family) (contains ATP/GTP binding P-loop)" FT misc_feature complement(42588..42612) FT /note="ttaatagtatcgtttgtttatgtag, splice branch and FT acceptor" FT intron complement(42588..42655) FT /note="confirmed intron" FT misc_feature complement(42650..42655) FT /note="gtaagt, splice donor sequence" FT misc_feature 43160..44778 FT /note="nominal overlap with cosmid SPBC18A7, EM:AL080287 S. FT pombe chromosome 2" FT CDS 44051..44778 FT /db_xref="SPTREMBL:O74403" FT /label=SPBC4F6.19c FT /note="SPBC4F6.19c, SIMILARITY:Mus musculus, Q9Z1K1, hs1 FT binding protein 3., (396 aa), fasta scores: opt: 134, FT E():0.048, (22.3% identity in 139 aa)" FT /partial FT /gene="SPBC4F6.19c" FT /gene="SPBC18A7.01" FT /product="hypothetical dipeptidase; metallopeptidase FT family" FT /protein_id="CAA20739.2" FT /translation="MVSFESSFERGTDFLNRNFKKCLFACISIFIFALLALSFLSLLQP FT DTVQRLYQCAVPSMIYVPPMINEAISIQHEEFNNRRRRLSAALREDKLDALIMEPTVSM FT DYFANITTGSWGLSERPFLGIIFSDDEPYPGDVASRIYFLVPKFELPRAKELVGKNIDA FT KYITWDEDENPYQVLYDRLGPLKLMIDGTVRNFIAQGLQYAGFTTFGVSPRVASLREIK FT SPAEVDIMSRVNIATVAAIRS" XX SQ Sequence 44778 BP; 14319 A; 8306 C; 8137 G; 14016 T; 0 other; gatcacataa agccgaatga tatcagtaat ccaactagca tagttaacat ctcattattg 60 aaaaataatt taatgacaat atgtttttag ctgtgaacat attaccttat ttctgcagtg 120 aaatcagatc atccacgtta tcctttaaaa atagataaat aattattcga aagttcaatg 180 acacatgcga tcaacagact tagagcccgt gcccgtgttt aaacattcca ttataaaagg 240 gaagttttac tcaaagaagt gcccttgttt cgaaaatttc ttgccattca aaaaactaaa 300 cactttaaca cagaacaagt cgcaggattt gacgaattga tgggataacg tcttttgccg 360 taatacgtta tatcctcaag tagatgcaga acattcacct cttgcaggag aaacgtacat 420 cttcatctct aagcacatca acttaaacct aacaagtatt tggtttggat ttccataaga 480 aaatgtcttt tgttccagta aacccgaaac cttttttgca aggtcttatt gggaaacctg 540 tccttgttcg tcttaaatgg ggtcaagagt ataaaggaac cttgcagtct gtagatagtt 600 atatgaattt gcaactttta aatgcagagg agttagtcga tggtgtaaaa acaggagatt 660 taggtgagat tttgatcagg ttagtaaatt ttaaatgtta gaattcaaat ttttatcgtg 720 aattaaatag cacatgataa ttcaatttcg aaacacatgt tagtttgttt ttgtcttata 780 ctaacgtgat tttaataggt gcaataatgt cctttgggtt ggcgagagta ctgtttaata 840 atgacaagtc gatatataag gctgaaggct aagaatttgt atttaattga ttaaaaaact 900 gagattgttt ttcaacgttg catacgcatg acttctcaac atatcctccc tcgtttgttg 960 tatgtattcg gttataaatt tggatccata caaaagtgca aacattcctc ttagatttat 1020 tggatattgt acttgcataa aaattactcg ttagtgattg gaattatgcg tatatatact 1080 tttcatggag tgacctaatt agaattgaag tttctaataa tttgctacaa agagatataa 1140 ccttacacct ttgtagaatt ttttctcaca tccaattttt cttcataaaa atctatttcg 1200 gcagatgcat ttgttttatc gagtaatcgg atactgacaa tattctcgct tgctctatgt 1260 agcctgaaaa aaaaaacagt acaacgaaat aactatgaac agtaaacatg atataaagtg 1320 tgtttcaaac ttcaattaat aaagtaaaac taacactttt atgtctcatg tgccatggca 1380 ggagaaatta tagtatatgc ttaccgaacc gaaaattaaa aactaatcat tctttttagc 1440 ggacgatttt tcatcggaaa cttcttcgtc ctcatcctca ctacgttcgt catgagtatc 1500 gttcgttgta aaagctctgt aaccaattcg aagaatcaaa ataagccagt aaatgtttac 1560 tagttgtaac gctgtgagca ggataagtgt tacgtcgcgc gaaatccagc acttgtattg 1620 ctctgcagcc caatctaggt caaatgagtt aatagtacgc atggttcccc aaactgccca 1680 cataatctta aagtttaggt aatgtcgcat gtagatccat acgaaaacga aaataacgaa 1740 aatagggtaa actattacag tgtttacata attcaagcat ttggataaag caagccaaat 1800 atcagaggtg tccatcgtaa taaaaacagc caaaccaatc caagtaaaat ggaaataata 1860 gctgagtccg atcaaaagca gggtgataat atggtgtacc acgagctctt taaaatcctt 1920 tctaggcttc tcaagttgta aaattagtac gagtgcttgt tggatccaat aggctgcttc 1980 tattaaataa aatgctttaa agctgccaac atggtaaaaa tgagggtatt cctcccaaaa 2040 agcatctgta ttaaaaaacc acataggagt ttgtttcata acatacaatc cccaagaacc 2100 cattacagta aagtatagac aagtataagc ttgctcttca aagcgacgaa gctttgcagg 2160 agctctaata ttaaagtgtc tgccaattct cgcaataatt tcctgcatta tgaattctct 2220 acaaaaagta aagaataaag cgtaaaaaag acaaaaggca atgtctaaac gtcctttacc 2280 atactgagcg gggttggtac cggggatagg ataactaagg aaaattccat acttaatata 2340 accattagga ttaacaaaat accagccgac gagcaaagtt aagagaatga gaggtacaat 2400 ccacgttttc tctttactac gaaggacagc attttgagca gcacgaccaa cgatagactt 2460 cgaccttctt cgtcgtcctc tatgctggac tggcatcgtc gaaaacgacc cagcagaaat 2520 gcttggaatc tagatgaaga aggcaattag ctaacttgaa aagattatat gctttaaata 2580 tctaaaatat aaattcttgc aataagaaat ttaactcaat acatatgtta aacactcaga 2640 aattgattaa ttttcaattt acaagtaatc ctaccaagaa ctcacttttt caacgacaaa 2700 ttgaacttac gtttttgaat ttttgagatt gacttcttct cgaggtatta ttacccatta 2760 ttgattcgga ccagcaaact gcgttgtggg tgttgtttgg tgctggtatg ctcgcatgag 2820 cacaacaatg gtatttgtac tacagactgg tacctcagga gcatattgct ggtaggggat 2880 ggaaatcagg caatattttt gaaaatttcg cacataccta aattgtttaa aacaactaaa 2940 ttatatgtct aaagaaaaac aagatactta aatatgatta ttgaacaagt tgaaattata 3000 tagtaataaa tgtcaagact caattgcatt ccaacctctt cagcagcaaa aacattggat 3060 aaaatcgaat atgggcaaac cttaatattc cataaaccag tatataaaaa aagccttaaa 3120 tactgtctac taggcattca agattacaat ctttcatacc aaatatatac actgagacat 3180 tacataaatc aaatataaca aaaagagatt agaaaaatga tagaattaaa tattattaat 3240 ttataaatat agaatatttt tcaaccaaaa aaaaaggtcc aactcatttt atgttccagt 3300 ctattgtaag ccgttaaacc catgttttta agtaatagtt tttaaaagaa atatgtattg 3360 tcttcgacat aggataaggt aagattactt agcaaatgcg cgggaggcac gactaacgcc 3420 tgacatgaca gcctttaatc cggcagaggt aacgtcagca tcaataccaa caccccagaa 3480 agaagtgtta ttgaaaatga tctcaacata agaagcagct ttgacgccgt taccagaacc 3540 aatagcatgt tcagagtatt gaccaatgtc aaatgaaata ttgaactgac ggcgtaaagc 3600 atcaaccaat gccgacaaag gtccatttcc aacaccctcg atcacaaccc gcgaaggagt 3660 atctttcttt tcacccttga tgtcaacaac gcatttaata catttgcttt gaggtccgtt 3720 gctagaaaga gtgtagtcgt ttacagagaa acggccggga aattcgaggt aatatgtggt 3780 ataaaacagg tcgctgatct caccaatgct aagctccttt ccttttgtgt cgctataatc 3840 cttaacaata ctaccaaatt caacttgcaa agcacgaggt aaatcgagac cacagttggt 3900 cttcaacaga tatgcgacac cacccttgcc agattgagag ttaacgcgga taatagcagc 3960 atactcggaa ttgacatcat ggggatccaa aggcaagtaa gggactttcc aaacaggatc 4020 gacagcttta cgctcatcgt aagccttcaa acccttagaa atggcatctt gatgagaacc 4080 agaaaaggcg gtaaagacaa gattgccagc ataaggatga cggggatgaa cgtttatctt 4140 gttacagtct tcagtaatac gaatgatttc atccaacttg gagaaatcga ggttaggaga 4200 aacaccttgg gtatacaagt tgaaagccaa agtaaccaag tctacattac cagtacgttc 4260 accattgcca aacaaacagc cctcaatacg gtcacctccg gcaagttgac caagttcagc 4320 tgctgcgaca gcagtaccac ggtcgttatg gggatggaga gaaacacaga ctttttcacg 4380 ttcactaatg ttagtggaaa agtactcaat taagtcagca tatgtgttgg gcgtagacat 4440 ttcgacagtg gcaggaagat tgaagataat aggttgggca gcagaaggtt tccacatacc 4500 cttgacagct tcacaaactt ccaaagcaaa gtctggttcg gtgtctgaaa aagtttcagg 4560 agaatattca aatccccagt tggtttcctt cgattcaaga gcatttttcg tagcagctgt 4620 tacgattttt gagcctttga tggctaaatc caatgtttct tgcttactgt tgcggaagac 4680 aacttcacgg aaaagaggag aacaggcatt atacaagtga acagtggcat tcttagcgcc 4740 tcgaagagcc tcaatcgtac gtaggatcaa aggctcacga gaaggagtaa gggcagaaat 4800 agtaacatcg tcaggaatca aacctggcgt ttcaatcaga tgacgaacaa atgcaaaatc 4860 agtttgagaa gcacttggga aaccaacctc aatttctttg aagccaatac tgcaaagcaa 4920 tttaaaatat ctcaatttct cctgcccatt cataggatcg ggtaaagcct gattaccatc 4980 acgcaagtcc gtagaaagcc agcgtggagc tttcgtcaaa accttgtttg gccattgacg 5040 gttgggtagt tgaattcctt taaatggctt atactttttg gagggatcct tgagcatccc 5100 tttggcaacg cggccagcag cctcaaaagt agatttcatg gagactgtag cgatttttgg 5160 acaaaatgag acgaactaac taattcgttt gaggactatt caaaagtcaa attgataaac 5220 ttaacgttta tagaaaattt cgtaagggaa ataatcaaaa caatcttaga tcgtctttca 5280 aataggccgt tgcaatgata ataataccaa ttgatgaatc tcacttaaca aaatacaaag 5340 aaaatttgat ttctttgatc gttacccgcc aaaaagcacg taaacaggat gttgtggaga 5400 aggacaaatt acctgaacac aaaaaacttc catatatgct gtctcgctat tcgacatgat 5460 ggtggcgata acgataacga tcggagatct gcgtacgaga tcattaaacc tgcttccttc 5520 ggtaaacaga tacccttagg gtaggtttag tgactgcctc aaatgttagg gaaactttga 5580 agtacttcag acacagcgaa gccttttaca ctatagagtc aagatgagcg ttggtaaagc 5640 aaaaggagct caaaaaactg ttcaaaaggg gattcacaat aaggttgctc gtaaggttcg 5700 tacttctacc accttccgtc ggtaagttta cttgtttgca tcgtttgcta tgcttcgctg 5760 tagctttcca agaattgtta agaatggcgt gaaaccaggc cgaatagtga ccattttaaa 5820 tgattagggc aagagattct aaagataaag tgaataatta gaacctattc caattgatta 5880 cttgaaaatt cattataggc ttgcaattct tatgcatacc gaagtttata gaatattaac 5940 gtgattataa aaaaataagt taaatttttt ttcgtactaa ttgttttagc cccaaaaccc 6000 tcgagcttgc ccgtaagccc aaatatgctc gtaagagtgt tccccatgcc tcccgtcttg 6060 atgaatacaa aattattgtc aacccaatta actcggaatc tgctatgaag aagattgagg 6120 atgacaatac tctcgtcttt catgtgcatt tgaaggctaa taagtttact attaaaaatg 6180 ctgtcaagaa actttacagt gttgatgctg ttaaaattaa cactttaatt cgtcccaatg 6240 gtaccaaaaa ggcatttgtc aagctttctg ccgatgccga tgcccttgat gtagccaacc 6300 gcattggctt cctttagctt aaaaactagt ttaataattc acttttgagc tccgaaattg 6360 catcatgtac tttctagtct cggtacaaat atataatttt tttaccctgc atatttctgc 6420 taagaagtgt agtaggagga gattgaattg attcgtgcct attggcatta gtaaaacatt 6480 taaaaacagg aaatttgtaa acagatatag tgatgttaag ttatggaact agaggacccc 6540 cattttaggt aagtgtatat cttaagatat gaaaattata tattatttat aagatggtta 6600 agataatagc aagtaatgat tcaaatatgc atttcgtatg actaaaaatt ttgatgatga 6660 aaagacagga caaccacggt caaaagaaag gataatcgtc aaaacacaaa cagatgagca 6720 attctttgta taaaaacacc acttcataac tgcgcgtttt acacgcctat accgtttctg 6780 aaaattaatg gcaaatcacc ccaatcgaat ctataagtat ttatgtcttc tgcgatcacg 6840 acgaaccaac attataccat aggatacaat tgcacccaat aacaagaaaa ccataaagtt 6900 tgtcaagtta tatggcgagt aagcatttcc cattgccttt tttatctcct tttcaaattc 6960 tgctaaatgt ttagaagtac catctgcagt ggaagattgc gcagatagag aatcatgtag 7020 caatttttca agggcattaa atctttcact tgggaactgt gaagtagaag aaatatcgtt 7080 caaacgctcc aaagcattag tcaacgcaaa atgcaaagag tccatcttct ggcgttgaga 7140 ttctactaga ttaaaaagct ttgccaaatc agcctttatt gcgttcaaac cttcagtgtc 7200 aataactgtt tgaggactag tattgtcacc gacgctttgc tttgtattgg aggtaggatt 7260 caaattttca ttattagatg tatctggagg aagtatattg aggttcgata aagccaccaa 7320 gtcttttgca gacgtagatt gagaggaaac tccaaaataa tacccctgag gcaaaatgac 7380 atcttttact tgaaagcagg gcttgtcatt cacaaataac tctaatccag attggtcacc 7440 gtatttgaga ataatattgt tcaaagcctc aggagagctc tcaatggtac atttagcaaa 7500 gggcggaaga tcggggtcag taaactgagc aagttcaaaa cttttatcat tcaaatagcc 7560 acgaacaaag attttaccag tttgatcgat ttcctgggaa atcagaaggc cgtcccactt 7620 atcggaggcg ccaaaaactg gaccttctga accgacagcg cttgtatacc aaatcgcaaa 7680 aaaggtgttt tcgttctctg atacatgagc tacaaatgaa gtcgatagct gccagccaac 7740 ttgtcgtaaa acgctagttg accaaaggga tccagagcgt gcttcattac tgtctttgct 7800 ggttaagtaa acgtaacctg aatcttcatc cacactaccg taccatttcc attcaacggg 7860 aatggcgtta cttagtgaat gaagttgcaa aaactgagat ttagggacgg cgtaagccaa 7920 tgtacaacaa aacgataata catgaaacag ggagcaaaac ttcatttttc tttacttcgt 7980 ttaaaaatag ataaatgaat attgtgaaag tatgccaaaa aaaagagaga gaaacagaaa 8040 ttgaaagaaa ggattatttg gttaagacca gggacttttt gctctattac ttatagaaaa 8100 agattactcc agtccttaaa tcctttagtt accgggaacc aaagtaaata gatgtatttt 8160 tggtttatta gttaccgtca gaaagtttat ctacaaaatt ccgtaaatgt gaaatgacaa 8220 caaccgccaa ctcaatcgta gtaaataagg atgatatttc gaaagtcacc taacgagtaa 8280 tgttagactt ccctatattt aaacatggca gctttctgag caactatgga tgttgcagta 8340 aaattgtata tgaattggtt taattgctcg aaagcattgt ttgtgtgcaa tgcaactttt 8400 caatgcgaag tgtatttaat gattataaca agcaataaat gtagtaaaaa agaccatttc 8460 tctactccac atcagagaca gaaaccagtt tttgtttttt tttaaattgt gactaaaaaa 8520 acaaaaaaac aatcaatgaa ttaagagtac cgtcatggtc gatgactaat tttagtcgtt 8580 aagaaaatta attgattgtt ccatcgaaat aaatttcata agcttaagag acatgaaaaa 8640 tacttaaaac aaaactctag agtaacttta atatttcgtt aatttaaaaa gttttgactt 8700 ggcacgataa ttcagatgta tgaataatgt aaaaacacac gcgtatttgt tcatttatga 8760 ggaaactgtg atggtgattt attcattgta tttttgaata cgcatatatt taaaagattt 8820 aagtatacaa tttcaattga gtcgtttgct gcatactaaa tccattttta gataccatgt 8880 ttttctcata accataaagg agcatgcttg cgcctcggta tatagcagtc gtgatctttt 8940 aaaagggtgt gtgggaaagg aaaatacaag tcgataaata catgaaatag attaaaaaaa 9000 taaaagttta agaaaatagt aactggtagg ctattttgaa gtcttatctc tatataaatc 9060 gatactaaac gtaatgaatg ctttagcatg gtgcattcat ccatgacatc tccactgctg 9120 ctttaaccat tccgtacaac aacaaagcca gtgcatttgg gttagggaat ccttccttta 9180 cagtttctgg cttcatttcc tttttttgta ataatttaat tgaaaggaaa gaattgaaga 9240 gatattgaat gccttagggg acgtagcata gatttgcagt ggttgttaga caggaaacaa 9300 attgcgggaa aatctcaaag tcgtttgact ttctgttgct caataaaaga aacaggagac 9360 ctgtttatac tagaatttct caaacaagag tttttacgac cgaaaattat cgaaacaact 9420 atattttttg gtcgtttatc ttgttcatcg aaaaagctaa gccggtttac ctgttcttct 9480 tccatcttcc tgctgctcta ataatctcat ttgttatctt ttcaagcttt gcttatttgt 9540 tttgattgta gaaacggctt tatcggcttg tgagcatcct tcttttcaca aacaatattg 9600 attgactact aatccgtttc taagccacga gcattcttgt aactagatcg ctttgcttat 9660 ttgttttcat ctcgtacaag aatttcttcg tccctttatt gttttctttt taatttttcg 9720 gatttcacgc tttttcgtaa tatttgtcat cttaggttcg caaggaaact ggtgccacga 9780 tttacgataa caaagtattt tttgtcaacc aagatttaca cgtttgtatt attttcacaa 9840 agttattatt ttattacatt actcagtcgg cttattttga gttgattgct aatttttgcc 9900 tctcaaaagt tcaagcagta attttatatc tgcttttttg tctgttgatc ccatttcctg 9960 atggagtacc gtaccaataa cgtacccgtc ggtaatgaga caaagtctgc cgctttaaat 10020 gcgttgccga aaattaaaat atctgactcg cccaaccgtc atcacaacct ggtggatgct 10080 tttatgcaat ctccttctta ttctacacaa ccaaaatccg ctgtagagcc tctgggttta 10140 tctttttctc ctgggtatat ttctccttct tctcagtctc cacatcatgg ccccgtaagg 10200 tctccatcaa gtcgaaaacc gctaccagca tctccttctc gtacgcggga tcatagcctg 10260 cgagtacctg tatctgggca ttcttatagc gctgacgaga agcctcgtga aagaagaaaa 10320 gtcataggca attatgtact aggtaaaacc attggggctg gtagcatggg gaaagttaaa 10380 gttgcgcatc atttaaaaac aggtgaacag tttgccatta aaatagttac ccgtcttcat 10440 ccagacataa cgaaggcaaa agctgctgct tctgctgagg ctactaaggc agcacaatca 10500 gaaaaaaaca aggaaattcg tactgttcgc gaagctgcct tatctacttt gctccgtcat 10560 ccgtatattt gcgaggcaag agatgtttat attactaata gtcattatta tatggtcttt 10620 gaatttgtcg acggtggtca aatgctggat tatattattt cacatggaaa attaaaagaa 10680 aagcaagctc gaaaatttgt gcgtcaaatt ggaagtgcgc tgagttattt gcatcaaaac 10740 tctgtggtgc acagagatct aaaaattgaa aatattttaa tttcgaagac cggtgacatc 10800 aaaattatcg attttggtct ttcaaatttg tatcgacgtc agtctcgctt gcgcacgttt 10860 tgtggttcat tatattttgc tgctccagaa cttttgaatg ctcaaccgta cattggtcca 10920 gaggtagacg tttggagttt tggaatagta ctttacgttc ttgtttgcgg aaaagtgcca 10980 tttgatgatc aaaatatgtc tgccttgcat gcgaaaataa aaaaaggtac cgtcgagtat 11040 ccaagttatt taagtagtga ttgtaaaggt ttactatcaa gaatgttggt tactgatcct 11100 ctcaagcgag ccacgcttga agaagttttg aaccatcctt ggatgattcg caattatgaa 11160 ggacctccag cttcgtttgc tccggaaaga tctccgatca ctcttccatt agatcctgaa 11220 attattaggg aaatgaacgg ttttgatttt ggaccaccag aaaaaattgt tcgtgaatta 11280 actaaggtaa ttagcagtga agcttatcaa tctttagcta aaactggatt ttattccggg 11340 cctaattcag ctgacaagaa aaagtctttc tttgaattcc ggattaggca tgctgcgcat 11400 gatatcgaga atccaatatt accatctctt tcaatgaaca ctgatattta tgatgcgttt 11460 catcctctca tttcaattta ttatttagtt tctgaacgtc gtgtatatga aaaaggtgga 11520 aattggaata ggatagcaaa aacaccagtt tctagcgttc cttcttcgcc agttcagcca 11580 actagttata atcgtacttt accgccaatg ccggaagttg ttgcctacaa aggcgacgaa 11640 gaatcacctc gtgtttctcg aaacacatca cttgcacgca gaaagccttt gcctgatacg 11700 gaatctcact ccccttctcc ttcagcaacc tcctccatca aaaagaatcc atccagcatt 11760 tttagaaggt tttcatcacg ccgaaaacaa aataagtctt ctacatctac tcttcaaatt 11820 agtgctcccc ttgagacctc acaatctcca ccaacacctc gaaccaagcc gtctcacaag 11880 cccccagtat cttacaagaa taaacttgtt acccaatctg ctattggaag atcaacctct 11940 gttcgtgagg gccgctatgc tggtatctcc agtcagatgg attcactaaa catggattca 12000 acagggccct ctgcatccaa tatggcaaat gcacctccgt cggttcgtaa taatcgtgta 12060 cttaatcctc gtggtgcttc cttggggcat gggcggatgt caacttctac gaccaaccgc 12120 caaaagcaaa tccttaatga aacgatgggc aatccggtgg acaagaactc tacttcccca 12180 tccaaatcta cggataaatt ggatcctata aagcctgttt tccttaaagg cttgttcagt 12240 gtttccacta catcgactaa aagtactgag tcaattcaac gagatcttat tcgggtaatg 12300 ggcatgcttg atattgagta taaagagatc aagggtggtt atgcatgtct atataaacct 12360 cagggtatcc gaacccctac aaaatcgact tctgttcata cacgacgtaa gccttcttat 12420 ggctctaatt ctaccactga ttcttatgga tcggtgccgg acacagtccc attagatgac 12480 aatggtgagt cgcctgcctc taaccttgcc tttgaaatat atattgtgaa agtccctata 12540 ctctctcttc gtggcgtttc ttttcatcga attagtggaa actcatggca atataagaca 12600 ttggctagtc gtattcttaa cgaattaaaa ttgtgattga ctattaaagc tgcatacttt 12660 tttgaaatta tttatttcac ttcattttac gttatgacca cctaattagt gtttatggtt 12720 tttaatacta agaccgcttc aggttgaact atattagacg ttgagctttt ttagagacga 12780 gaaactagac ctctaatgct cttgcctgtg aaagcaaaca gatgccagag gcatgtaaag 12840 tcaacgtgta aatgcaccct cgttcgctta tgtttaagcc agatacataa ggctactata 12900 attaatgata tatcttatag taattcgttc acttatatag tctaatacga cgtttttgtt 12960 gatacttatc tagcagtaat attattatta acccataact ataaaatacc aaaaaaccat 13020 tgtataaaaa cctaaatgaa aacccgtgct atatgaaaag tagctaagta aaaacccttt 13080 tttacttctt ccttttttgc agaacttcca aagcactaat tgagtccatt ccgataatat 13140 tatcatgaac ttcttcgttg gctaattttt cagccatatt tacaagaccg ctcgtcaagt 13200 atctaccaga aaatcctgtt cttatttttt cgtgtaataa gggagcaagc tctgagcgaa 13260 gatgcgctat ctgtttctta ttcttactag attcagattt ttttggcaaa tccggatcct 13320 catcatcaga actttcaact cccaattcct gagccatcga ttttaaccaa gcttcctcac 13380 gtcccactct tccgtctttt ctagtgagat ttacaatttt atgtgctaag acgaccctcg 13440 tttttaaaat gtccaatatt gacatatcca caggaaaatt aataaaggtc tcgattttct 13500 ttttcaaccg ataacatagt cgtttcagct gtgacagttc tttaggacca cacattaaaa 13560 ttgaaacgcc atcttcgtta gcgcgagcgg tacgaccgct tctatgaaca tacatatcag 13620 ctgtatgagg aacatgataa tgaattacgt gcgtaacact aggaatatca ataccacggg 13680 cggccacatc agtgcaaaca aggactcctt taggattatt tttgaacctt gttagttagt 13740 aacatataaa taaaaataac ttacttttca agagattgaa gtcttttttt ctgatctaat 13800 tgagcatgta gaggatagga tggaactttt aactcattta gaaaaggagt gattctctta 13860 atatcctcaa taccattggc aaaaaccatg gtttttccag gataacgcat gatcaaataa 13920 taaagataca agtctttttc agctggagca cactctatga gcccttctaa tacgcggctt 13980 gccactgcac tttgaggatt ggcatccaaa aatttgggtt tgccaaagaa acgaacctcc 14040 ttcaacatat tttctatgca gtcgttagta agtgagaaag taaaatattt ctaattgaac 14100 atacccatcg ggctgttgta tttctcagtt atattgcctt tcatattctt tttaaggcgt 14160 tgctgtaaac cctcatcgaa agttgcagaa aagataaaag tctgacgctg agtatgcatg 14220 ggatttccta aaatttcaag tagtttgctc aattcttcaa aatgactttt ttgcagtaaa 14280 cgatctgctt catctaatac caaacacttg attttcttaa agtttcctgt aaggttgttc 14340 tcgttgatga cagaccacaa gcgacccgga gttgcaacca caacgtgagg gtgcttgtta 14400 agaagcctct gctgcttctg tactgctaat ccaccggtta tagacataac acgaatgtta 14460 ggacttggct tgataagttc aaagtgttgg caaatttgat gagcaagttc tctggtagga 14520 gcaacaacta gagcctgtac gtattttgca tctacattgc gaagacaatg ctctaaaatg 14580 ggaatgccaa aagctaaagt ttttcctgaa ccggtatctg cctttccaat gatatcaaat 14640 ccaatagaag cttcaggaat taccaatgat tgaattggca tcggttttga aaagccagct 14700 ttagataacg agccaagcat ttccggtgaa agtgaaaagt gtgcccaagc agagacgtcc 14760 acaccatgag aattgtgttc atcctcttct tctaatgtag agaattcatt atagttttta 14820 gaagtcacct ttgatcctag tgaagtcatt tcaatagtag gggaagtacg ttttcccttt 14880 ttcttttttt cactagcttc tttttgatct ttttttcgct tttccggctt tttatctttt 14940 ttttcatgaa cttctggtaa ctgtttgtta ataaattaga taataaacaa ttatacctca 15000 taaattactt ctttcatagc accttttggc tgatatttga tatccacacc ttcaatctct 15060 tccaagccca taaacccatc gaagtcgtct aggtggtcag gaagcttgac ttccttccat 15120 ttaagctcgt ccaatgcagc tttctttggc atcgtgatca aagcgttgaa aagtgtagta 15180 gtttgctcca catagaaaat gtaggtagac aaaaatttac actaagaatt ggaacgaggg 15240 aataaaaata attgcatcgt ataagctaat agaaaacaaa taattaaatg ttacgaagac 15300 attaaacgac gattggtttt agcaattcaa tgctttgcca tgttttgcat aatttctaaa 15360 tagtacaacc attttgtatt aaaaatattg cttgagaatt ttagaatcga atgatctgag 15420 ctacagtgct tacaagagta gtaaacacaa acgatgttac tactatagtt ctaattcggc 15480 tagcaattgg tacaggtgaa aggaacattc ttattacttt gaaaatttga catctcagtc 15540 cttctcttaa ataataataa taaaaatagg aattatagat atgacagaat aatataaggg 15600 tctttatgtt cacgcagctg tttagaatta tgtcgtataa gatgtaggtt gggaagctaa 15660 tacataatta atgcacatcc ataaagtttt tgaagaaaaa aggtagattg atcggtcata 15720 atttagcatt tcattttcag actatcattg aaatggaaga agtttttatt tcattttgga 15780 ttcttcgaaa agtactcttt tgtgaattct atgggttcat tcattagctt cttaaatgag 15840 gctttagaaa atccataata acttacttgg gatcatattt tataaaagca agcttaggag 15900 cagcttttgg acgtgaacga acgtagaaaa atccagtgcc agcggtggac aataatttta 15960 caagcaaact gaaaaataaa tgttaaaaat gcgcattaaa ttaagcatgt atgtcttacc 16020 gagctttatt ctttttagcc attctggata tacgtacagt gcaagcggta agttaaaggt 16080 tttgtagtta caccagggtt tgtgggcgag ctcttttaac ttgatggata acttgcagtc 16140 agaaatgtaa aattgaaagt ttgcaattca aagatattgt tttgagtaat gagaaagcct 16200 ttttgcaatc caatttttat taaatttggt tgtgtacaat cgaggctttt caataggtta 16260 tttttttgtt ttaggtagac tatagaacta ttagtaaaga taaaaggctc atcaatgaat 16320 tacttgtttt gaaaaaaagc atttagattt gaaattctaa ttgagaaaca tgcatgacgg 16380 cacttaagaa cgaaagacga acagtaagaa taaaaaaatt agaaagaatt tttgaataaa 16440 aataaaataa aataaaaaat aaaaaaatgt taataaggaa agtataacaa attgagtctg 16500 ctgcgtctct tctcctgatg tctgccaatt taacagagag gaataattaa caaactataa 16560 gtaatcttat aaatagaagt tgctgttcta ttaacattcg aagaaaaaat atgaagtgat 16620 gaacaactct tgaaaaattc ttttttttta ttacaattat tattgttttt taattattgg 16680 ctgtagatgg gtatttaatt aaagtccaat cgcgtctttg ccaatttata atcttatttg 16740 tatttctaca ttttttttgg aaagaatgat attcaaatga aagaaccaat tttctttcag 16800 gaaaaattct tttagttaaa atgacatgta ctagatgaat taggacgtta agaatgaact 16860 aattgcaata gcatagtttg ctagcgtgaa aaaaaaacac agatggaaat tagcgagcct 16920 agtaaagaaa catttatgac gaggtggttc taaaaagcct ttcgtgtata tatatatata 16980 tattcggctc taaacaaacg caagctttaa gtatcattgt aactgtaaat tattggcaat 17040 actgaaagta taagacgatc ctcaagttgt aagcaaacct aattcatttg ctgtaccaag 17100 actaggatgg atgagttaca agtcacttta agtgtttatg ggtccaaaga gaatataaaa 17160 tgtgttttcc caattttaca agggttagcc aaataaagaa tgcaaatgaa caaatcgcat 17220 gaattgcgga agctagtgac attgtatgac gatctgcccg aaatcccaag tccgtatctc 17280 atccgcgaaa ttgagacata tcacgatgca tacggagaaa atctatacaa cgcaagtata 17340 gccgcaccca aagacggata tagaatagac tggagaaggc tacatccctc ggatatggag 17400 actgaatgaa agaattgaga gagtatttaa agctcattaa gtgcaatgtt tacgattgtt 17460 attacggttc tacatggtca atagtatggg aaattttaaa ataaacattt ttcctggttg 17520 tgaaaatgat ggagagaagc aacgaaaata tctttaactg atgctttata tatgtagaat 17580 aaaaattgag ttggaaatta cagcagggat agtaaacaag tcaaggatat gttacagttg 17640 tcattagaat aacaaaaggt ttaataacta tcttttaaag aggatttgac attgtactaa 17700 gggctgagac aactcgcatt aaataagcaa aggctgaatt aagtaaaaga atattcgcac 17760 ttaatagagg aatactatgt taaatatagg atggatttgc tgtgtatata taaaattatt 17820 atcctcttat atatacatat aattatcgtt aattattatt tatattttat tttattttct 17880 tatcttttcc ttggttttta tgtatttact agtaaatcta taataatcat taactttaat 17940 aactttcttc aactgatcaa tttcccaacc aaaatgcttt gttatttgtt ctttaagctt 18000 gctatgttct ttagctgcgt gtctatcatc tcttcttgtt tggcttggca cgtgccattt 18060 taccatttct tgcttcctcc taccttttag gccttaatat taaccccctg ggtcatcttt 18120 tggcatatag ggtaaagggg ccaaactcac tatccaagat aagtctaagt atgcaactgt 18180 taacatttca gttaagcacg ttgtctccta taagcaagta taacgtagtt taaaaagaac 18240 gttaagttaa ttagtctgca cataatacaa acatgggata gtgagacaat atcgtctgtt 18300 agagtaaatt ttcctttctt gaaagatttt ccatttttgt gcatgaaaag gcgtaattta 18360 agatcatgcg atgggtagta caggtcaaat tgataaaccg acttttacca gtttgtgcta 18420 tcagatctca cactgtgctc tccttccgtc gcattatttt gttatttttt gagctgagta 18480 ttcccgtaat ccaaggacaa gcgtcagggt gtgtacgata gttgatctgt ttaataaaga 18540 aacatattat tagaaaaatt aggaatcatc aggaaatcaa caagttccaa aatgggtctt 18600 tgctccccaa gtgttccctt atacactcga tcaagagatg aaagtatcgg gtcagtaccc 18660 gtgcttcttt ggcttgggct tactaagtag ctatagtaaa acctggtgac atttctgttt 18720 ttgttacaca ctgtcagttt tatcctataa ccctatacta cactgtaccc ccgccgtgtg 18780 atcggcgcac agtcacgaaa attgcagtca tagttacagt tggaaaaaat agtgcatggg 18840 ccacaaaaag taagttaagt attagaagaa caataagaat agtatagact cttcatgaat 18900 acaatgttct ctatgcaata gacatattat ttcatttcgt aggtaaaata acatttgacg 18960 tatgtaaggt tagcgtgctc aataaagtaa ctagctatca gataaaaatt tcgtctgata 19020 atttttatcc ttgacatcag tctatgtgcg aggcacaaga cacaggcagt tgcgaagtcg 19080 gattaattca aacatatagg gttagtggca tttcaagttg tagtgtgagg tacaaatgct 19140 actaggtgat acttccgata tattgaatgg aaacgtgggg tcaaccaaat ctcctcaagt 19200 ggttgccttc atgaacgaac gacaagcgga agaacgggga aaaatgggat gatcgcttcc 19260 acttttcatc aaagattcga cgttataacg ttacttcagg agcttagcag cttgtgaaaa 19320 ctggacagac ccactgtatg atcgtgtcaa tgttcttggc tgaacaaaaa ttacgcaatt 19380 tttccatcaa taaagacagt cccgtacaag gaagaatatt taaatatgag acgctgccga 19440 ccatcagata attcttattt ttcactctat tcttacttag ttaagttgcc ttcacctcca 19500 tcttatctga gtgaagttaa gtaaactcag caaacataag tggattgaac atccaaggca 19560 aagtctaata gctttcatcg aaagaaaagt gaaaagagaa gaacagaatt taaatagact 19620 tcaacctatt ctgaatcttt gttttccttt ccttccttct ttccttggat cagcattctg 19680 tgatttggtg cttgaatcct ttgattaaat ttcaaaaaaa tatcctccac caaaaaaaaa 19740 gtagtttacc aacaattatt ttaactttac gttttagcgg aaaataagcg gcgtgcccac 19800 attgatcgta tctggatact tatcagatca tcagatatcg actaaatttt attttcaaaa 19860 gattttcatt atatttccgc tgacattgtc gcaagtgtgt gccatttctc tttgatatat 19920 cggtctgcct ttgttaactt tgctttataa aagcgtgcga gtgtatacta ttttcttcct 19980 cccccttgtc cactctcatt attgaagaga aaattgttaa gaaattgaag tatcagtcat 20040 tgttcaatac tgctgtgtct tctattttga acctttttaa tttcgagcgt cttttctttt 20100 cgtttttctg tttgtttcgt cctttgtttt tggttgccct tttgttaaag ataaccgatc 20160 catactaatc atcatcttaa ttctctttgg tttcttttaa aatttccatt gtaacatccc 20220 tggctgatct agaaaagaaa tcaatactat tccctcctaa tcctttttta atttagctat 20280 tttaaatttc tgcatttcta tattgttttc ccaagatgcg tctgaaatca ttctccacaa 20340 ctctcgatac attgcgaaga agatttaacg attctagtag cgaagaggat aaattggaaa 20400 aaaacattca ggatgaaact tccataaagg aagtttcatt gcaagatgca aagcaatccg 20460 atgaaaaggg tgttgaggaa aaggttttta atgacgagag cttttctatc gatgtcgccc 20520 ctaaacccga agatgaactt tctggcattg tcaaagctag ataccttacc gaacattcct 20580 ctaggatctc tttttacata tgctattttt caattttttt gcttttcttc gccattagtt 20640 tccaagcaga atgttattat tcattaactg cttatgctac ttctgctttt gcaggtcatt 20700 cattgctttc caccattgca gttgcaaaca atattatttc tgctgccatt aaaccccctc 20760 ttgctcgtct ctcagatgtc tttggacgtc tggaagcttt tctcttctct cttttacttt 20820 acctagtcgg tctcatttta atggccgctt ccacgaatgt tcaaacatat gctggtggta 20880 gtgttttgta taatgctgga tacactggcg ttgagttgat tatgacaatc tttatggcgg 20940 atacctcttc tatggctaac cgctctcttg ttttaggcat ttcttacctg ccattcgtcg 21000 taacaatttg gatcggcccc agagttgcgc aggaatttta tatgcattct acatggcgct 21060 ggggtattgc tgtatggacc attcttattc ctgcttgctc tattcctttc cttgccgttt 21120 attcatatta tcaattccga gcttggcggg agggtgcttt gaagggaacg cttacaatta 21180 accctgttga attgttcaaa aaactcgaca ttattggttt aattttgatg actgcgggcc 21240 ttgcccttgt cctgctttcc atcagtttgg ctagttatga tactggaaaa tggagtgatg 21300 ctaaattcat cgttatgatt attattggtg gtttatgtct tattgctttt gttttatatg 21360 aaatatttgt tgccagtttc cctgcattgc cattccgtct tatgcgtgag cctactattg 21420 gagcttgctg tgctatgtct tttctgttct acatcacctt ttactgttgg gataactact 21480 attatagttt cttgcaagtc gttcattaca catctattac tgctgctgga tacatatcat 21540 acacctactc attcacttct tgtgcaaccg gattcttttt gggaattctc attcgtctta 21600 ctaagagata caaatggtac tttgttgctt caattcctgt ttacattctt ggccaaggtt 21660 taatgattcg atacagaggc gagcaatata attggggtta tcaaattatg cctcaaatta 21720 tcgttggtat tggtggtggt gttattgcaa atctacttac tgtcgctgtt caaactgttg 21780 tcagcactga gaattttgct attgtcacag cccttgttag taccgttaca cccatcggtg 21840 gtgctgttgg aagtgctata tcgggtgcaa tctggaacag cgtgatgccc aagcgtttag 21900 aaaagaatct accaagcgac ttgaaagacc aagcatatac catttttgag agtttaaccg 21960 tccaattaag ttatactaga ggcactgacg ctagaaatgc catcattctt tcttatagtg 22020 aagtccaaaa gattttgacg agtgtcgcaa ctggttttgc tggtgccatg atatttccgg 22080 tttggttcgt cgctaatccc agactttcaa cagtcaaaac ccacattttt gattcgaagg 22140 aaagcaaagt ttaaaaatca tatgggagat aataaaaatc gtaattcgca tttcggcaga 22200 tatttatgtt tagtttcttc aaattttcaa cgcttaacat ctgtctcgaa tgctcaacgc 22260 atttttgtta aaggatgcga ttagtcgatg ctattttttc accgcctttc acgaagttcg 22320 tgcggttctg ttaatttcta attggtattg ccaactgggt aggtaatttc tttggtattt 22380 atttgttaat tttagtttga catctataaa acacctaata aaatcgttaa gtttatttaa 22440 attggtttag tttttaacac agcaatgttc gtaaataata agtagaaaaa ttctcttttt 22500 taccgtgttt tcatttaaca tatacatctc ttactaatac ttttttttaa gcaatgtata 22560 atggacatga taagtgtccc cttgaaatgg cttagcgttg gcattgtgtt cattagaaac 22620 taacttatag cattgtatat ctcgctattt taaaatctta tttagcaaat aaagctatat 22680 ttttatgata aaatgtatct acctagtccg tcaacataaa gtaccccttc tatcggttga 22740 ggttgtctgt cgactgcaca atacgaggat taaaccaggt ttacaccgca aagactcgta 22800 ccttgaaagt tatataatgg ttctttactt tcccttttaa atagtaattc atttaataat 22860 acttataaat ggattatcca tcatttcatg aagaccctac aaaggacgaa tctaccgtcg 22920 ctgaacagcg aaaaggccaa agcaatgaag aaaagccgtt gattgattta aatgacagtt 22980 tggatgaaca aaggaatgct tataatgaac attgcaagaa tcatgatcag caaccaagtc 23040 agcaagtcag aaatatggaa gacgaggcta atcaatatga acaaactgac agcagcagtg 23100 atcaagaagt tatgaatgaa aaacaatcat tagataaaga aaatagaaat gataacatac 23160 ctcatgaaaa taatcccggg cagcaagaaa ttaatgaacc tatttttgat tttcatatgt 23220 ttttagaaca attgcgttcc agttctgcgg aaccagttgc caagtacttg aaaagttttc 23280 tttcagaatt cacgaaaaga cgatggactg ttaattacca ggtcaaattg attcgtgact 23340 ttttaaagtt tataaatgaa aaaatcgaac aatatgaacc atgggcttct ggttcccagg 23400 ctgaaattga taatgctaaa gaggggatgg agaagttagt tttaaacaga ttatacacaa 23460 gtttattttc tcctgaaatt gcaaagtctg gcataccttt gagcagtgaa cattcggatg 23520 atgttgagga agaccgagtt ttgtctgaga aaatggaact atttcaatgg attacagagg 23580 agaacttaga tataaaaaag caaaaatcta gctcaaaatt ctttaagctt gctgctgatg 23640 aattaagaag aataaatgat taccacgctc cccgggacaa gattatctgt cttttgaact 23700 gttgcaaggt tatttttagc tacctaagaa acgttgttaa agaggagtca gcggatatgt 23760 ttgttcccat tttgattttt gtagtccttc aagcaaggcc ggcccactta gtatctaata 23820 ttcaatacat acaaaggttt cgttctcccg aaaaactcac gggagaagtt atgtactatt 23880 tatctactct aatgggagct atgtccttca tcgaaacact ggattgtagt tctctaacta 23940 taacggaaga agagtttaat gcacaaatag agaagtcgat caagaagatg gaagagagaa 24000 agttgagcga aaagtctgaa tcaaaaacgg ccgtaaacga gaatgcaacc tacaaggatc 24060 cggttctttc tcgaggactt tcatcatcca tagatgtatc gactggtgtt gcattggtaa 24120 atttaccaga agagcttgaa aatatgaaat acttgcaaat agacactcct gaaagcaaag 24180 aatatcctcg tagcacaagg ccgagagctc ttctcatagt ggctctttca caactgattc 24240 tggaaaaaga tcacgcagaa actcaaacaa gtatgttggt tctagcgatc gacctcccta 24300 tcgagtatct cgtgcatatt cctcgtctgc tacccattct cccatcgttc atgaagagca 24360 gccagtggat gatggattac aacaaaatga tgacctgcga gaggcaacaa cagcgtctct 24420 tgagacagct gaagctgaaa ggctacaagc tcgggaaaag gctgaagcaa ttacggcttt 24480 aagagctatg tttccagcgt ttgacagtga agtgattgaa gttgtgttaa atgcgcaaca 24540 aggaaggctt agttcatcta ttgattccct tttggagatg agttaacatt tgtagtttta 24600 tgaaatactc aagtataatt tattattatt attattattt ttaaatacaa acttctaact 24660 ttttacgacc tgatgttcta ccggttccag gagtcatctt tgctgcttta gaaccaaact 24720 gaatagccct ctttttttct tgactagcta agggacaacc taatcgacgt cctaattcac 24780 gtaaaattag tttgtcacct ccaactaaat ctagacgcat tttatcagta gttttcattt 24840 tgctaaacaa agccatcaga cgctcatcga gaaaaggata acgcacctct ttcccttgat 24900 tagacattac cctgtcatct ctgcccaagt tacgatgtgg aatacgatca atgtccaatt 24960 gcagttcttc ttcaagaccg gccatacctt tccgttcaaa cgctcgtagg tgccgcatat 25020 aaccaccgag ctgctcatca gcccccaggc cactgatgag gactttagct tttatagtat 25080 aggaaggtaa ttgatgtttc agtttgatat catccacgtt ttgtaaaagt acaccacgcc 25140 cttgtgaagc aaaataaaaa gctaatccaa tagaaagatc cataactgaa tcgttcggat 25200 agataagtgt tttgactatt tcctgtgctt cacatacttc tgtataagga acgtttatag 25260 caacaaaatt ccattttcga gcagggcaaa ctgaaataag ctcctgccag ccttgtaatc 25320 cagtttgtct atcaggacat acgtcgtatg catcaaaatt gtcaggaaga agtcccgtct 25380 ctctgtcacg gtatgtctct gtaaatcttg ggttttcaaa agccacatta attaaatcga 25440 tggactcgtt attgggaact atgtcgtgca ttagccgtgc taatacaccg caatccactc 25500 ccccagagta aagaacgcaa actcggctat aatgactaca gtcaaggttt gaagagcaca 25560 gtttggggat tgttaaaact ctatcttgaa gcgctttgat aagatatgta tgcaatgtgt 25620 ccacagtgtc tgaagagatt gagcccatga gaaaggactc atccacagga ggaagagggt 25680 ttgttttttc cagttgcatt aatgatttag agaagttaat ttttgggatc aagtccacct 25740 gcacactatg aaacccaggc tcaacttctc ggaaatcact agaatttcct acacttgaga 25800 gaacgaaatt actatctcgt aaactataca aaagggatct tcttcctaag cgatctcttc 25860 cccaccacaa tgtgtttgta cgaacttggt agtaaacaaa agcaaaaggt ccttgaatac 25920 ttcccaaaat tttttcaatg tcgcccgggt tattgtttaa aagttcaaaa agttttgcac 25980 cgtcgttttc attacgattg agcgtaaatt tgtgatgatc gctatggttt atttgccaaa 26040 tttctccatt ccaacacaaa acgtttccaa aactgtcaac atgaggttga ggcgttaaat 26100 gatcagaagg gccacgtaaa tgcaaaacgc ttgactcaaa gtgcaaattc caaggtccgc 26160 tattcaattt atgcttacca aaaaaatcag gtcctctagc ccgaatcctt tttcgtaaag 26220 ctgaaaaaga tggactttca agaagattat ctctgtcttc cgctaaggcg aaaagaattc 26280 cgcacataaa ctattctcaa acacttttgc ttctaacaaa tctacagtca aaaaagtgtt 26340 ttttccttta acgacgtttg tgtggtacag tgtgatcgta attttatata caatatcatt 26400 ttgcgacaca ttgcaacgct tataagtaac tacacactga acagactcac gggtctacat 26460 attttttctt atacaattat acttacaact ggtaaagaat tttcttaggt caatctgtag 26520 cttgaaagcc aaaattaggt ttctatttat gaaacaataa gcgaaatgct gtatgcctga 26580 caaagcataa tggggtagtt aatgacattt aaagagctgt aacaatacag taagcattaa 26640 taacgcgctc cacaataatc tactgccaaa gtataaaaaa aataaattat aaaaagatat 26700 tgtaccatat tatgaaatcg caacatataa aattgtccaa caaataacat tgatttcgtt 26760 tggaacattt tctgcatagg aatggcttaa ttcactttaa ttactaatat attcgcattt 26820 ttttactttc tgctggtata caaacattga atacgtactc tctaagtatt cgttaaaggt 26880 acaatgttac ctattatgag gctggtttct ataacaacga atgtttgttt atattttgga 26940 atatacactt aaacaaagcc aacacttatt agctaaaaca ctttggataa agcaaatatt 27000 actgctttct aaataataac tacttgctta caattgcatt tttttaatac agctagtttt 27060 tttgggggac tccgctcttt gagatatata tccttacgtt ggcaacaatt ttctataagt 27120 taatcccagc ttgatttttg tttttccttc cttatccttc tcttcctatt ttttatcttg 27180 tttttaagtg ttgcggctag atttataccc tgcgagcttg gctatcctga tttcttaagg 27240 ttgtcaacga tcctgaattc tttccgttga ttagtgtcct gatagttgag aagcatatca 27300 gcaaatgcat tcaccaattc cagaattacc aaggtaatct attgtcttat tgttattacc 27360 caattaggta tctaacttcg tttttgtaga tttgaacgtc gattgactgg tcctcgtgct 27420 gctccttctt cgccggtctc tactaatggc tccccgctaa acaatttagt tcgttctcgg 27480 ttatctgatg gagcacttaa ctttactgga ggtcgaatag ctacaccatt accgcaacca 27540 agtttgaaga ctcctgaatc tcctttgtcc aagaggaatc caacaataaa acaaaatcgt 27600 gtacgttttg atctgcctga tgacgagctc tctcgttcta atgtttcgtc gccggaaaaa 27660 acactactaa cctctgcttc tacttctact ttcgatagct taaaaaagga gcttttacct 27720 gaattgccat ctcttgcata cagtgacgac gatgagtttc ctagttcgcc ggaggaattg 27780 aattcacatg ttaattatcc agacgtacga aatgtttacg attgtcatac cggtttacag 27840 ccgcttgttg atcatgattg cattgaagac agacaaaaaa ccttcgcatc caaacaactt 27900 cctactcttc ctttacagaa atccagtaaa ctttccaatc gtagacccgc tttgcattct 27960 tttcattctg ctcctgctaa tagcttatat cctttgccca cccccacttc acaattgcct 28020 agcaacttgt cctcaaataa tttatttcaa tcagattcac ttaagccttc aatggtatct 28080 tctcatacat ctacaaaacc agttctttat agaggcaatt ctgaaaaatc ctgtcatagt 28140 tgcggcggtt ctttacgcgc tggcagaata attagtgctt caggaaagaa attacaccct 28200 caatgcttca aatgcgatac ttgttcccag aacttagagc acgttggatt ttattaccgc 28260 gagggaaaat tttattgtca tctagactat catgaacagt tcagtcctcg ctgtaagcac 28320 tgcaaaaccc caattgaaga ccaagcggtc catatcaaca atgattggtt tcatgaaaat 28380 catcattttt gcgctggttg ctctgaagtt tttaatgtaa atataccctg tatttaccgt 28440 gacgacctat actggtgtca gacttgttat gataataagt atgctgttaa gtgcaagaaa 28500 tgccgtaaac ccattttggg gatcagtgta aaagggtctg atggtgaata tcatagccaa 28560 tgttggacct gcggagcttg taatgcccta cttggagatg agggttattt tatgatagaa 28620 aataccccta tttgccgtcc ttgcaaggcg atatcagtca agtttaattt ggattaactc 28680 agacttactc atcactttct ttttcttttt tttttgttat tttttcactt ctttcatcga 28740 ttttagcttt ataaggaaag ctgtcttgga aatcttggag attttaaatc atttcattta 28800 atccacaaag tccagcatgt ttacttgcat ttaaacttgc tgtattttta taattaagca 28860 attaatgatt aggtaactat agatatataa aaagcactat tgaatttcaa cggttacgat 28920 ttttgatatc acgtaatact taaatacttt agataactta ccaaaaaata aaaaataaaa 28980 acatattcag tttgcacaaa tgcattttaa actttcgaaa acccctatat tcctattaaa 29040 tatccaaaat caagtacgaa aacaatcttt tcgacttgtt agcaaaacta taatacagca 29100 ttgaaaaagt atcttttgca gtaaacacta ccaaacatta tttttaaaag tagagttttt 29160 ctaaatttta aagcaagtga agaaaacaaa aatatttaag acgtttcaaa cctttttcaa 29220 gtccacatcc gaatttctcc accagcacct gcactgaata accaggcttc ttttggatgc 29280 cagcatgtgg ataaaacacc gacattatca accactttat gattccgcaa aatcttaaga 29340 ggaacaatca agggattagc cagaaggtca ctgtaaacac gaccgtggaa cacttgaaca 29400 tcaccatcat cagagccaga gcaaaatagt ggaagggaag gatgatatga gacatcgcga 29460 agagcacgtg aatgatatcg aagattttta tatggtttag aagaaaagtc taagtcgaac 29520 caacatagcc ttttatcata ggaacctatt atgacatggt ccccactcga atggacactt 29580 aaactcgaaa cccatttgac accagttaac aaggtcttta caagctcttg cttaacaaga 29640 ttgtatatgc ggacatatcg ttgagtagca accagaagat aaggcatagt agggtgaaac 29700 gtaacagctt gcacagaacc tttagactta gaaaatggcg attgacttgc acctcttgac 29760 aactgatgaa taagaaccgc ctggctagaa gaagtaggag aagaagtagc taggtaatca 29820 ccgcgacgat gccaagacaa ggacttaatg ctactgggag tagaaacagt agcatggact 29880 ataccaccat gtaattgtaa agattgtttg gctcctcttc tccatattgc actagattct 29940 tggtaaggag cagaagtaaa caattcttta gaagcttcaa tctgctcgtc agaaaagatc 30000 gggggtgtga tgaaatagac tgtttcatca acagcaacag caagcactgg actatctgaa 30060 agaggtcccc aagcaagtga ttgaattata gagctctttg tagagtgact taaagattca 30120 ttaaccgcat cctcatcgct atcaatatta tgtgcattac caaaactgtc caagctgcat 30180 ttccaaacac aacgaccagt cattacttcc caaatacgta aaactccatc atcacctcca 30240 cttgcaagcc aatttccgct aacatggacc gaaagacaac gaacacgacc tttatgaccg 30300 atgaaaacat tggtgcagcg tgtcggaaat ggacgaagct cagagggggt aggaagttta 30360 ggaagtaacg attctggatc aatattaagt ttggtacgtc taacacgggg agctaaataa 30420 agatccaagc aacgttcaaa cttctccttt ataaggtttg agtaagcagg aacaacacgt 30480 aaggatttat atttcttagg aaagtccgaa gactgtttta agtattcttc aggagggtta 30540 tagctttcct cgtgtgatgg aggaggaagc ttaggtgcag gtgcatagtc caactttctc 30600 tggttaacag ttgcttgatc atcatccgcc caaagatcat gatctgcata attgctttga 30660 ctttcgcgtt cacgttcagc acgctgttca gaagtgagaa ttcttccttt acggatagca 30720 taagcaagct gtaaaatacg cttttgttca tgcttagagg gagcaaatcg acgtttgggc 30780 tcaggagcgc ttgaaagagg agtttcccgt acggtgtttg taaaaaaatc atcataatca 30840 ggatatggat caaagttttc gtcaggaatc tcggattgag caagtcgctt tagcaaaccg 30900 agctcttccg tagtcaagtt aaccggcttt cccgtcatag gatcaactat tccagtccat 30960 cctttgtcct tatcaatgct agcaattaaa gaatccaaag cagcaggtgt cgcaggtcgg 31020 gtaatctttt ttccatctat atcataattt atatacaaat tctcatcata aggagattca 31080 tatagtccag gagcgacatc ttctgtagag gaatcggaag aataaccagc atcgatttcc 31140 tcaaattctt cttcatcatc agcatcctca aaatcatccg gggataactc tggagtagaa 31200 cgtccacttt cagaagaata ttccccttct tcttcctcgg ataactcggc cgtcaaagat 31260 ggaatttcct catcaacatc ttttttaaaa cttggttcat gtgaagaact ctcagtctca 31320 acctcatttg gcacatttga aactccttta gacttttctt tttccttatc cttctctacg 31380 ccaacgttgg aattggctct tttggacctg gacctcttcc tattcatgcc agtctccatc 31440 ttggaaaaag acaaggtagt ttagttcctg ttcaaagttt ctttttgctt tttctgcaaa 31500 gtagagtacg cttccgttaa catgtataag gatttgcaac gaaatgataa tataccgagt 31560 gtcattaaat aatatagagt gttgaagatt tcttctcgtt aatttcgaaa aagtctaaag 31620 tacatgttct taggaaaaaa gaaattgtcg ttgtaccatg aactcaaata gcacattatt 31680 tgtgcgaaat cttgccttcc agacaaagca agatgattta acaaacttct tttccgatgt 31740 cggacctatc aagcatgcag tagtggttac taatccggaa acaggtgaaa atcgaggata 31800 tggatttgta acattttcaa tgcttgaaga tgctcaaaga gcagctaagg agttgaaaaa 31860 taaaaaatta catggaagaa ttcttcgatt ggatttcgct actccccgta aacgatcgga 31920 ggtagacaca gaccagaata aggctgttaa gaagacaatt aggcaggata atcgacctcg 31980 tctaattatc cgaaatcttc cttggtcaat taaaaagcca caacatttgg agcctcattt 32040 ttcaaagttt ggtaaagttc gtgaaattaa aatccctaca aagggtggag gtcgtatgtg 32100 cggcttcgcc tttgtctgga tgaaagatcg taaagctgct gaggaagcca tgaattctct 32160 aaatgggaca gaaattgatg gtcgtcctat tgccgttgac tgggcagtta gtaaagatgc 32220 attcgaagct actacattaa aggatgcatc ttctgaggag gaaaacaaag aatttgtatc 32280 tgatgaagga cactcaattg taactgaaga tgcttctgcg gactcagaat ctgaggagga 32340 agtggatggg cattcggagg gtaaagaatt ggcgggggaa agtgaagaag agggtagcaa 32400 tgtcgacgat gtagaggatt ctggtgattc atcttctgac aaaaattcta taaatcatga 32460 aattcgggac aatgaaggat tggaggacac tgtgtttgtt cgcaaccttt tgtttgagtg 32520 tacggaacaa gaattgtata atcactttcg tcaatttggg ccgcttgcat acgctaagct 32580 agttaaggat cctgctactg atcgttcatt gggaaggggt tttattaagt tccgttatga 32640 aaaggattgt caaaattgtc ttgaaatggc ttctcagtta cctacacaag agcctactga 32700 ggctgaaaaa cgttttcttc catcagtttt agtagatgag ggaattgata ctgacagcgt 32760 aagttctcgt ttccttctac atggtcgttt gttgaaagtt acgagcgctg ttacacgaaa 32820 agaggcttcg gacattaatc aaaaaagttt acaagagaga aagcaaaaaa tggggaaagg 32880 tgttgatagg cgtcatctat ttcttctcaa tgaaggtaaa attgctgccg atcatccttt 32940 gtttaacagt ttatctgaga ctgacaaaac gttaagaagt cagtctatcg cccaacgtaa 33000 aaaattattg gagaaaaatc ccaccttaca tctttctctt aatcgtctct ctattcgtaa 33060 tatttctaga cacattgatc ctaaaatttt agcaatgctg ggtagacaag ctattcgtgg 33120 atttatggac gacgtttcga aaggattacg agctaacata actgaagagg aagagaatct 33180 tgacaaggga cacagactta aaagggggaa aagtggtggt gtacttaagc aagctaaggt 33240 agaaactgag aaggctggtg ctggaagatc aaagggtttt ggtttcatgc aatttatttc 33300 tcataaatat gcacttatgg ctttacgctg gctgaatgga cgggaaatta ctgttaaaaa 33360 aataatagat gcagaaattg agtgggcgcg aaagcataaa attcctgagc cgcagctacc 33420 aaatatcgat tacaatgatc gtcctcgtcg tctaattgtc gaatttgcta ttgaaaacat 33480 tcaggttgtt aagcgacgtc aagaaaagga aaagtcgttt cggcaaaaag caaaacaatt 33540 gaagcaacaa gaagatgagg ataatctgaa aaggaagcgt tctgaatccg atgtagagga 33600 taacgaagcg aaagaaaagc aggcgaaagt tgctcgtatc atccaaagaa aaaggatgaa 33660 gagacgctca cgaaaaaact aagctactca tttttgtcat tatgaagaca gatgatctat 33720 attttgtgtg gaaaataggt ttaagaaaac tttaaatgct ttaattaatt tctatttaga 33780 gggaataaaa tcaataattt ggtttggggg ttaatcattc agttcaaata gaaaactggg 33840 aaattaattt acgaaacact attagcgaat cctttgtata gatacggtta acataatgta 33900 aaagaatgag gcatagtcaa ataagttaat ataagaaata aatcaagttt gttttaaatt 33960 tattgcttca ggtcttttaa tggtagaatg ggacataaaa ggctgctgca ctgcttctag 34020 aaaacgattg accttggtag gaccccatcc ttctaactgt tctagttcat ctctggaagc 34080 cactaaagct ctctctaaag aaccaaactt tgataaaagg gacaggctat cgctcttgtt 34140 gataccgcga atactagtca aaaaagattg cacctgagaa agataatcag ttgatggctt 34200 ctccattata agtgcaggtg acatgttttc ataagcctta tacgtttcta gatatcgagc 34260 agcctcttca gaagaccagg ccaaaataag tgtatactga ttcacgatac tagttttgac 34320 taattcttga attgaagcct ggtgattctc aacatcaact aaaatcagta agattcttaa 34380 attgtatgat ttcccgagtt tagatatccg tgaataaatg tattcaggat gcaagtgatg 34440 gtatttcaag ctagcatgat gtaagtcagt ccttcaataa acgaattatg ctttggggaa 34500 tttaacatac cttaagaaca aagagcaaat acctgttccc ataacaaaat cgggaactat 34560 gtcggtgtat tcccatggta catttcgaac gtgaggctat tgtttatgag caagctttat 34620 ccacgagtaa gaaacttacc aataaaggat ttcctttcta taagaagtta atatagtcct 34680 tatcagaatg gtgataatcc cactacagaa aagaaaaaag caagattaaa aatgcatttt 34740 caacctgcta taacaaacca tgcgatctgt cttcagcttc ttacctgtcg agggtttacc 34800 aaaatagagt gagctgtaac cctagacact ttttgaggag ttggctgttg agcaaaacca 34860 gcttttttct ctacttcttc taaggcgcta actgcaagct gctcaaattc ctcatcatcg 34920 atatcagaca ttgtctaaaa tatataaaaa aaaaaaacag aactgctcaa gagcttcgct 34980 aatgaatact gtttcaatat ctgttgtact caattgggaa atttggtagg agtaagttga 35040 ccataccaag cttatattat gttactaaaa cagcatggtt tctggctact acgttgttga 35100 aaacgttcta tgacttatta tttttttact agttagcgga aaaccgaaga aatagcaaac 35160 tcctatagaa tgggtatatc aacttacatg tcattaagat aaaacattta cacggcgtcc 35220 caatgtcttg taatagactt aactgattct tactttctat accgatttac atatacaaac 35280 taaatttcgt tgaataaatg gacatacaat acaaatgacg attaaagata ttgtaaacaa 35340 attcattaat tttcaaattg tagcactact tgagctttat cgtctaagat gttagtaaat 35400 taaggaacaa aatttgaagc aaaaaaattt ttgaggaaaa aatcagaatt aaaaattggg 35460 tttctcttcg tttgctgggg tcttaatccc gctcagtaac acggaccaat tttggtcatc 35520 atagcttcca aaaaccgttt tttgacatac ctatcactat aagtaaaatg aggactctct 35580 atgattttta tgcctcgctt taaaaatgta tatgacaaat aatcttactt ccaaaaatgc 35640 ggcatcttca gtagagagat aacgcttttc gatataagga aaggccaact tcatcgtagt 35700 agcaccagct ttttatagta aaaaatttta aggtcgagat catgtaccag aaaagaatgg 35760 aaaaataaaa aaataggata taaaaattag attactcttg ggacattaca tataaagaac 35820 aaagcataaa atagatacca agtctggtcg ataaagaacg caaggatttc tttggacgga 35880 gacctatatg tcttgtaaat gagtgcttta atagcatcca aggtgtcatt tgtttttgcc 35940 tttaaactaa accaaaatgt cgcttcgaca gagtgtgaaa ttctgtcaaa ggtatttacg 36000 agagccacaa cttcttctgg tcttaagtca cttaattgag tttcaggctc caaaagtaat 36060 ttaagggccg tgccataacc tgtgatttga acttttcccc aaagtctaca tttgtcgcag 36120 ccaacacaat ccattatgcg agaaatatca cggaaatgtt tgcgaaagct atccttaaat 36180 ctcttagcct cttcatcggc aaagaactgc tcgcgattta taacatgacg atcctggtaa 36240 gcgtgataaa ccaactgttc aaatgctgtg tgagtacgcc aatcaacatc tttatcagta 36300 ggacaaaagg taaaagaact gtcgctagta atgtttttca tttgggttgc aatttgaaca 36360 agcgcttgat gtaacaacgc gtaattgaaa aaaatatttt caatgcgatc gggaaaactg 36420 ccaaccttgg cgcgccacca atccaaattt tgggtccaac gttgctcttc gacatcataa 36480 taattttgac aaacatgagt tgatatgcta gcatgaaatc ctgaaattat tctgttaaac 36540 atacgctttt ctaggcaagc aacagatgga gataaagaag tgtcatcatg gttctccgtg 36600 aacaagttca aaggtatttg atttggtcta aaaagagcat tacttttagg ttgttcagat 36660 ggattatcgt cgtcgtcaac cacaaaacag ttttgctcgt aaatgcttcg ccaaatcgca 36720 gctgaatgat caccagcata tccagtaaat ctttctgggt tttgcacaag ggatacatac 36780 acgtattcat cgggagaagt ggaattatca aggtagcagt aatccaagtc aggattatat 36840 ttccaattgc attttgtatc atttttctta gaatggggtt caaaatcact gagctttttc 36900 catactttgg gtatttcaat ctcattcaat gatttaactg cgcaaccttg gttactacac 36960 attgcgttgt cattttccca taaagggcag cttgatctat agagatttac tctgtagtat 37020 gaaaagtaat cactacgctc agttaagaca ggtactaatg agcgaacttt ggattgcatt 37080 tgataaatgc ctgtagaact agtgtctgtt tgagagatta ttatctccgg aagcaacaaa 37140 aaattccaaa tggcattcca aatagaaatg agctttgtaa ttccaatcat tgcaatattt 37200 ttctctgtca ctaaattatt ttttaaaaga aattctggtt atattttatt tttttaacga 37260 ttttgtattg aattctaagg atttgtgtag tactcgtact accgcgagta ttggagaagg 37320 acaaagaagg aattgataaa tatactgcga cctcatatcc ttaaattgtg cttagctaat 37380 gcaatagagt atgttttact ttaaagcttt ttatgttttt ctagaaaatt aagcacggaa 37440 actcgtcaat acttccttat gcttatcaac gctatatatt ttagaatttg tgcaatacga 37500 ataatagttg aaaatattct tgaaaaatat acatcgccac cggcatatgc aatatatttt 37560 aaggcgctct gctaaactag tatttctaaa gcaaaagcaa atttttatca cacatgtgct 37620 gaatttatta ttatacctga attagatatt tgagtttgag agctgtaaat tccggtcgta 37680 aacactgaac ataaaccagg tagaaaattc atcatcaatt ggaacgattc tttgatgtta 37740 catttacaag catcgaaaaa ttattatcaa acatgttagc taactccact attatatatc 37800 gaagagagtt tttgaaagaa aaataagcag tttactagta attacgcata acttgcttct 37860 taaccactac aatttcagac aattgcacat aagagatttg tgtaatcggt gtttgaataa 37920 ataaaaatga taataaataa ttgcgtaaaa tatttaaagc cgctattcaa tatggtcatc 37980 actaagataa taaagaaatt atcagataga aggttttcat aataacatta atcctcatga 38040 cttgtagatt gtggctcaag cttatttgct ttaaactcaa gttcaccatc caaaacgtcg 38100 atcacaacat tttcgtccga cttaatttct ccctgaataa ttttcatcgc cattgtgttc 38160 aaaatacgct tctgtattaa gcgattcaaa ggtctagcgc catacgctgg agaataacct 38220 ttttcagcaa gccatttgcg agctgcttct gtaactgtaa ggattatacg acggtcatta 38280 agacgttgtt gaacttcgtc caaacgaacg tttactatgt cttcaaggtt cttttccgat 38340 aatttgttga aaacaatttg gtcgtcaatt ctgttcaaaa attcaggagg ataatatttc 38400 tgtacaacat ccataacggc atccctggat ttgggggtga cagtagtact aggatcagca 38460 accaagatat cgcttcccaa attcgaggtc ataacaatca aggtagatcg gaaatccact 38520 ttacgtcctt gtgaatcggt caaaaatcct tcgtctagta cttgtagaag aaggttggta 38580 atatcatgat gcgctttttc taattcgtca aacaaaagta cggcgtatgg tttgcgacgc 38640 acagcttcag tcaactctcc agattcttca taaccaatat atccaggagg actaccaatc 38700 agacgcgcaa ttgtatgttt ctcctgaaac tcggacatat caaaacgaat catagccttg 38760 tcagtgtcaa atagaaactc tgctaaagct ttggtaagtg cagtcttacc tacaccggta 38820 ggtccaagga aaaggaatga tgccaaaggt ctgttggtgt tttggagacc tgcgcgtgat 38880 aaacgaactg catcggctat cgctttcaaa gcttcgtcct gaccaataat cttcttgcca 38940 atagtttgtt ccatattaag gagcttgtct ctttcaccac gcattaaatt agtggtagga 39000 attcctgtcg cccttgatac aacaaccgca atatcatcgc tagtaaccga atcatgtacc 39060 atggatggct tcttttcttc aagcgttttc tcttcctttg gaacactacg ctccaattca 39120 ggaataatcg catattggag ctcagaagca cgggcataat taccttcacg ttgtgttctc 39180 tcaagctcta ttcgagcctg ttcaagttca gttttagcct tcttgatgga gtccaaaagc 39240 tttctctctt cttcccatgc cgcagatagt ttatcttgtt cctccttcaa atcagtgagc 39300 ttggactcca atttctcacg tcgctcaacc gatgtcgtgt cagtttcctt cctaagggat 39360 tccaattcaa tttgtatagt catgatttga cggtctaaac gccgcaattc atcaggttta 39420 gactcttgtt gtaagcgaag agaggagcag gcttcatcga ctaaatcaat ggctttatcg 39480 ggaagaaatc gatcggtgat gtatctagcg ctgtacgtag ctgctgttac caaagcatcg 39540 tcagtgatac gtacaccatg atgaacttcg tatcgttctt tcagaccacg aagaattgag 39600 atggtgtcag ctacagaagg ttcatttacc ataactgctt gaaatcttct tgccaaagca 39660 gcgtctttct cgatgtattt tctgtattcc tccaaggttg tcgcaccaca acagtgcaat 39720 ttaccacggg ctaaagcagg ttttaataga ttgctggcat caattgagcc ttcagcttta 39780 ccaaagccaa gtaaaaggtg catttcatca acaaacaaaa tgacctttcc ttcagctcct 39840 tccaggtcac tcagtacaga ttttaaacgt tcctcaaaat ctccccgaaa tttggctcct 39900 gaaatgagag cgcctaaatc taggacaata acacgtttat ccttcatgga ctcagggacc 39960 tctccacgaa tgattcgcga ggctaatccc tccataattg ctgttttacc tacaccagcc 40020 ggaccaacta acgcaggatt attctttgtg cgtcgagaga gaatttggat ggttctttga 40080 atctcttctt cacgcccaat tacaggatcc aattttcctt gtttagccaa ggctgttaag 40140 tctgtgccat attcttccaa agcggctcct tgtttgcgtc cgccgcctaa atccattcga 40200 aaatttcctc catttggatt tgctgcataa aagcgtactt gcttccatcc aaactttgga 40260 gatctcttag ctatgagtac agaagcatta cttggtctta tagaaaatgg tgtttcagct 40320 aacagccgtt tttcaaaaat gggtcgagta ctcaatgccc gaagagaagt ttttaaactt 40380 ccttggtacc tacggagcga ttgtattcgt atcggaatac tcttaggtaa aatattcatg 40440 gtttgcgaaa tcttctcatt ttcttaccta ctgcttatat atatatatat gaatctataa 40500 agtgtcggct aactaaagaa ttacctggaa ggtagtagca aattcttata acgagctaac 40560 taaggttggc aaataacgcg tgcgttgctt ttcgtaaaag agctctttta aactgcaagc 40620 tgcatcaaat tagtaagagc aactgacaat ttttcttact cagtagcctt atcaccgata 40680 tctatattgt ggtcaaagaa tctacaattc attagcatcc atcgtatgat agcgttaaat 40740 aaaagaatat gaggtaaaag attatatgta gcacgaattg ctcttggacg aagcaactga 40800 gaagaacaga atgaaagtaa ataagcgacg tttataagaa atttcaaaaa gggcctttct 40860 caacgaagta ttgttatcaa tttctgtttt tataattttc tattctaata gctttcttaa 40920 tgtctacaag attagaatga ttggcagatt tgctgtgtaa ttgctaattt taagaatacg 40980 tttttgcaag ctattaatta aaaactattt gggattaatt gaaacagcgg tatagactat 41040 ttataagtcg ttagctgtaa ctcttttgat agattcaaaa cgtttagcaa attgtatact 41100 taaatcattc atatccttac tggtacatac tgctacaatt taaaaatttg tcaatataat 41160 gttatttcaa caaacattga gtgtaataca tgaattcctg agcatcgccc catatagcaa 41220 gcatttataa aatgttcatc aaacattact gagtaaggaa gagataataa ccattcaggg 41280 taaaatcgca accaaaacag taaatctagc aagaaaagaa ggtgaatatc caacttccat 41340 taactatgga atgcaaaaca ctcgtgcatc accagctgac aagtgcatac gatttctcta 41400 cttcatgagg agtcagccat ggacgcctaa cttcatgaag gtcgcttcgt ggcaaagcaa 41460 gctgttcatt tttctctatc aatcaagaac catcaaatat gctgaatcaa aattcaagcc 41520 gaatcactaa taaaccccca aatagataca caagatccca ttccatttac caattctcaa 41580 gctcgcagtc catgaaaggt atgcgttaca ataacaatga ctgaacagag cactgtacgt 41640 gcattataga aaagtcaaac cggttaattt tcaagacacc ctgcatgcaa taaaaactta 41700 tgatacatag catgcaaagt aattaccaaa gaccaaagct cccaaagctt ttatgagtgg 41760 caagcgaatg actagtggga actacaactt tggcaaccca tacctttagg ataggaacta 41820 gggagttaaa aatgcaacct tcatccctac ttcatgcata aagtaattag aagatagcaa 41880 cgggacggaa atgcaaatgc gaattcagta atgaacatcc gaaactatct aagacacatg 41940 attaagatat acgccaaaaa aaatgttaca gttccttttc tagaagcagt gaagtattcg 42000 aacaaatagt taatggaatt cacgggaaat agaaaatata gctattaaac atgtggacga 42060 ctgaactcag ggaaaaagta acaagtatat aaaatttact gattcttaag attggtagaa 42120 agccattcaa gaccttcata aagaccgtcg ccgctagtgg cacaagtggc ttgaatgtac 42180 cattgacgat gacgaagaga atgaagtcct agcttatcag tgatctcagc ggcattcata 42240 gcattaggca aatcttgttt gttggcaaag accaacaaaa gcgcgtcacg aagctcatct 42300 tcattgagca tacgttgtaa ctcctcatgg gcttcggaaa tacgttcacg atcattagaa 42360 tcaacaacga agataatacc ttgcgtgttt tggaaatagt gtctccacaa gggacgaatc 42420 ttgtcttgtc caccaacatc ccatacagtg aaagagatat tgcgatactc aacagtttca 42480 acgttgaaac caatggtagg aattgtggtg acaatttcgc caagcttgag cttatataaa 42540 atcgtagttt taccagcagc atcaagacca accatgagaa tacgcatcta cataaacaaa 42600 cgatactatt aataaaagtc cttctttttc aaacttttca aaggttttca cttacctccc 42660 tcttgccaaa gaggctttgg aacaatttgc taatactcaa acccattatg tcttatattc 42720 tttcgtaccg aatgtttttc tatttggtag tggttttggt ggaagaagaa atttatctgg 42780 tggtgtgcgg tgcagtatgg ctggaattac ggtgaccgtt atcaccagaa atgaaccacc 42840 tatgcttttc tttgaaaata ttcgcctttc atgtctgaaa ttttttattt attaaataaa 42900 aatctcggat aaaaattctc cctgtaaatt tatgtatttt ttttttaccc atcctcagcc 42960 caaacttcca ccctgttacc agtttgactt gtaaataaaa attaagtgaa actgattata 43020 gatcttaaca tctaaaatag atactatttt tttaaactac agtatgttaa atatccataa 43080 ttcccttctt gctaaaaatc aaagagtcta agcatggatg tcaacctgtt ttcttaactt 43140 cgacaacaac tctcttataa tgaccgtgac tgaaaagaac ctttgaattt tttttaaaat 43200 ttttcacttt ttttattatc ttatatacta tgggctatca attatcgcgt caattatata 43260 ggtaactcgt tacatttgtt ttgtaaatca cagtacctaa aagatcataa accttttaaa 43320 aatgaaggat taaacactct tatgctgcag gaactcaaaa ttgaaggatg aattaaccga 43380 atgcgaatca acaagttcac tttcatagct tattttgagt aacaaggtga ttttgaggtg 43440 taagatgaaa ccttcatttc taattctatg acactgtgaa aagtattcat gaatgttttt 43500 aatatttaaa aaagtggtca atttatagct cttaaacaag gcagtaaact ataaaataat 43560 aatagaaaca taaccatcaa gagcatatga aaccatgcga gatcaattgc aaaaatgaag 43620 cttcttttca aatgtaaagc tctttttaag ttaacttaaa atgagtacgt gaaacactag 43680 ggcttactga aatttttgga attgaactat acagcgacta ctttattatt gttgattaac 43740 attcctttga ggtatttata tttgacttga agaccaacta ttaaagagta agattttgat 43800 tgaaatagga caggggaatt tttcatttgt taggaaacta attgatacac caaattttca 43860 aatctcatat aggttttttt tataaaacta ataaacgaaa taaagctttt taatttaata 43920 aaaatatata caaaagcgac gatattgtag catcttcggt taactcaatg ctgtaatctg 43980 atagtcagta atatctgaca tactatatag ttcagcacca cctctcttca atcagcagaa 44040 ttgctcaaaa atggtttctt ttgaatcaag ttttgaacga ggtaccgatt ttttgaatag 44100 aaattttaag aaatgtctct tcgcatgcat ttccatcttc atttttgcgc ttttagcatt 44160 atcattccta tcactgttac aaccagatac agtgcaaagg ctttaccaat gcgctgttcc 44220 ctcaatgatt tatgttccac cgatgattaa tgaagcaatt tcaatacaac atgaagaatt 44280 caacaatcgt aggcggagac tttcggctgc acttcgtgaa gataagttgg atgctctaat 44340 tatggagcct acagtttcaa tggattattt tgcaaatatc actactggct cctggggtct 44400 ttctgagcga ccttttttgg gaataatatt ttcagacgat gaaccctatc caggagacgt 44460 ggcatcaaga atatattttc tagtacctaa gtttgagcta ccacgtgcta aagaattggt 44520 tggcaaaaac attgatgcga aatacatcac ttgggatgaa gacgaaaacc cttatcaagt 44580 tttatatgac cggttaggac ctttgaagtt aatgatagat ggtactgtgc gaaatttcat 44640 tgcacaaggt ttacagtatg ctggatttac cacatttggg gtgtcccccc gtgttgcgag 44700 tttacgggaa ataaaaagtc cagctgaggt agatattatg tcaagggtca atattgcaac 44760 tgtggcagct atacgatc 44778 //