ID   SPBC4C3    standard; DNA; FUN; 29767 BP.
XX
AC   AL021730;
XX
SV   AL021730.2
XX
DT   03-FEB-1998 (Rel. 54, Created)
DT   07-MAR-2002 (Rel. 71, Last updated, Version 4)
XX
DE   S.pombe chromosome II cosmid c4C3.
XX
KW   ade1; dna-directed rna polymerase i 190 kd subunit; fork head domain;
KW   GHMP_kinases; homoserine kinase; nuc1; phosphoribosylamine-glycine ligase;
KW   proteasome component precursor; protein kinase phosphorylase; sep1.
XX
OS   Schizosaccharomyces pombe (fission yeast)
OC   Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes;
OC   Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
XX
RN   [1]
RP   1-29767
RA   Wood V., Rajandream M.A., Barrell B.G., Lauber J., Hilbert H.,
RA   Duesterhoeft A;
RT   ;
RL   Submitted (02-FEB-1998) to the EMBL/GenBank/DDBJ databases.
RL   European Schizosaccharomyces genome sequencing project, Sanger Centre, The
RL   Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail:
RL   barrell@sanger.ac.uk and QIAGEN GmbH, Max-Volmer-Str 4, D-40724 Hilden,
RL   Germany
XX
DR   GOA; O43056; O43056.
DR   GOA; O43057; O43057.
DR   GOA; O43058; O43058.
DR   GOA; O43061; O43061.
DR   GOA; O43062; O43062.
DR   GOA; O43063; O43063.
DR   GOA; O43064; O43064.
DR   GOA; P15398; P15398.
DR   GOA; P20772; P20772.
DR   GOA; Q9UUM6; Q9UUM6.
DR   SPTREMBL; O43059; O43059.
DR   SPTREMBL; O43060; O43060.
DR   SPTREMBL; O43061; O43061.
DR   SPTREMBL; O43062; O43062.
DR   SPTREMBL; O43064; O43064.
DR   SPTREMBL; Q9UUM6; Q9UUM6.
DR   SWISS-PROT; O43056; KHSE_SCHPO.
DR   SWISS-PROT; O43057; MSS4_SCHPO.
DR   SWISS-PROT; O43058; SEP1_SCHPO.
DR   SWISS-PROT; O43063; PSB6_SCHPO.
DR   SWISS-PROT; P15398; RPA1_SCHPO.
DR   SWISS-PROT; P20772; PUR2_SCHPO.
XX
CC   Notes:
CC   Details of yeast sequencing at the Sanger Centre are available on
CC   the World Wide Web.
CC   (URL, http://www.sanger.ac.uk/Projects/S_pombe/)
CC   During 1995 to 1996 about 80% of S. pombe chromosome 1 was sequenced
CC   by the Sanger Centre.  The sequencing of the S. pombe genome is now
CC   being continued with funding from The European Commission.
CC   Fourteen European sequencing laboratories, including the Sanger Centre,
CC   are participating in the project.
CC   Protein coding regions (CDS) have been predicted with the help
CC   of computer analysis using the Genefinder program in PomBase
CC   (an ACEDB database) with additional predictions for the
CC   branch-acceptor sites supplied by the program Sp3splice.
CC   CAUTION: It is possible that for any individual CDS we may have
CC   underestimated or overestimated the number of introns/exons or
CC   we may not have chosen the correct splice donor/acceptor sites.
CC   CDS are numbered using the following system eg SPBC25H2.01c.
CC   SP (S. pombe), B (chromosome 2), c25H2 (cosmid name),
CC   .01 (first CDS), c (complementary strand).
CC   The more significant matches with motifs in the PROSITE
CC   database are also included but some of these may be fortuitous.
CC   The length in codons is given for each CDS.
CC   IMPORTANT: This sequence MAY NOT be the entire insert of
CC   the sequenced clone.  It may be shorter because we only
CC   sequence overlapping sections once, or longer, because we
CC   arrange for a small overlap between neighbouring submissions.
CC   Cosmid c4C3 no overlaps at present
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..29767
FT                   /chromosome="II"
FT                   /db_xref="taxon:4896"
FT                   /organism="Schizosaccharomyces pombe"
FT                   /strain="972h-"
FT                   /clone="cosmid c4C3"
FT                   /map="IIR"
FT   misc_feature    1..108
FT                   /note="nominal overlap with cosmid SPBC1778, EM:AL021730 S.
FT                   pombe chromosome 2"
FT   CDS             join(complement(1330..1530),complement(990..1226),
FT                   complement(826..935),complement(592..762),
FT                   complement(1..541))
FT                   /codon_start=1
FT                   /db_xref="GOA:O43064"
FT                   /db_xref="SPTREMBL:O43064"
FT                   /note="SPBC4C3.11, len:419, SIMILARITY:Mus musculus,
FT                   AAD38505, phosphoinositide-dependent protein kinase 1.,
FT                   (559 aa), fasta scores: opt: 966, E():0, (47.3% identity in
FT                   319 aa)"
FT                   /partial
FT                   /gene="SPBC4C3.11"
FT                   /gene="SPBC1778.10c"
FT                   /product="putative phosphoinositide-dependent protein
FT                   kinase 1"
FT                   /protein_id="CAA16833.1"
FT                   /translation="MDLEHKRISRSTLPDYADPDYFEARGERNPVKPQSSNVVPGTSHI
FT                   GSIKSPADYVFGDIIGDGSFSKVRRATDKKSWKEYAIKVLDKKYIVKENKVKYVNIERD
FT                   SMMRLNGFPGISRLFHTFQDDLKLYYVLELAPNGELLQYIKKYRFLDENCVRFYAAEIL
FT                   SSIEYMHSCGIIHRDLKPENILFDGNMHVKITDFGTAKILPPKYVNSPDYTTFPSSFVG
FT                   TAEYVAPELLSRQVVSKSSDLWAFACVVYQMIVGSPPFHGSNPNNIFKKIMSLEYELPK
FT                   LLPPDIVPLFSHLFRIQPSDRSTTQQIKQFPFFATITWDNLWTQDPPPMQSFRPNYNIA
FT                   IPNAPAYYRSNVTAAAAANAAAAFASASIVKHQETARRQELPTVNRFTAPTAHYGYASL
FT                   RSHQMPVDRLYYKLVPSSESI"
FT   misc_feature    join(complement(826..926),complement(592..762),
FT                   complement(319..541))
FT                   /note="Match to PF00069 pkinase, Eukaryotic protein kinase
FT                   domain Score 134.15"
FT   misc_feature    complement(542..557)
FT                   /note="ctgacaaatatttaag, splice branch and acceptor"
FT   misc_feature    complement(586..591)
FT                   /note="gtaaga, splice donor sequence"
FT   misc_feature    complement(763..783)
FT                   /note="ctaattctaacctattttttag, splice branch and acceptor"
FT   misc_feature    complement(820..825)
FT                   /note="gtatgt, splice donor sequence"
FT   misc_feature    complement(936..953)
FT                   /note="ttaactaagctttggtag, splice branch and acceptor"
FT   misc_feature    complement(984..989)
FT                   /note="gtatat, splice donor sequence"
FT   misc_feature    complement(990..1226)
FT                   /note="Match to PF00069 pkinase, Eukaryotic protein kinase
FT                   domain Score 33.05"
FT   misc_feature    complement(1227..1240)
FT                   /note="ctaatattcgttag, splice branch and acceptor"
FT   misc_feature    complement(1324..1329)
FT                   /note="gtaagt, splice donor sequence"
FT   CDS             join(2816..2871,2915..2997,3050..3182,3366..3774)
FT                   /db_xref="GOA:O43063"
FT                   /db_xref="SWISS-PROT:O43063"
FT                   /note="SPBC4C3.10c, len:226, SIMILARITY:Saccharomyces
FT                   cerevisiae, PRCD_YEAST, proteasome component pre3 , (215
FT                   aa), fasta scores: opt: 906, E():0, (62.5% identity in 208
FT                   aa)"
FT                   /gene="SPBC4C3.10c"
FT                   /EC_number="3.4.25.1"
FT                   /product="20S proteasome component (beta 1)"
FT                   /protein_id="CAA16832.1"
FT                   /translation="MATTVKDTMNVDINAIKKGEIRMGTTITALRYKDGVILAADSRTT
FT                   MGAYIANRVTDKLTQLTDNIWCCRSGSAADTQTVADLLKYYLSMYRIQFGHDPSVHTAA
FT                   TLASEMCYQNKNMLSAGLIVAGYDEKTGGDVYSIPLGGSLHKQPLAIGGSGSAFIYGFC
FT                   DANFRENMTQEEAVEFLKNAVALAMERDGSSGGTIRMVILNKDGMERKFFAIDTANPIP
FT                   VFTH"
FT   misc_feature    2872..2877
FT                   /note="gtatga, splice donor sequence"
FT   misc_feature    2903..2914
FT                   /note="ctgactttgtag, splice branch and acceptor"
FT   misc_feature    join(2934..2997,3050..3182,3366..3597)
FT                   /note="Match to PF00227 proteasome, Proteasome A-type and
FT                   B-type Score 138.11"
FT   misc_feature    2998..3003
FT                   /note="gtgtgt, splice donor sequence"
FT   misc_feature    3037..3049
FT                   /note="ctaacgttgctag, splice branch and acceptor"
FT   misc_feature    3183..3188
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    3351..3365
FT                   /note="ctaacgattatgaag, splice branch and acceptor"
FT   CDS             complement(4374..5504)
FT                   /db_xref="GOA:O43062"
FT                   /db_xref="SPTREMBL:O43062"
FT                   /note="SPBC4C3.09, len:376, SIMILARITY:Schizosaccharomyces
FT                   pombe, YA0C_SCHPO, hypothetical 43.7 kD protein, (371 aa),
FT                   fasta scores: opt: 1288, E():0, (49.1% identity in 373 aa)"
FT                   /note="also similar to adjacent sequence SPBC4C3.08
FT                   putative duplication"
FT                   /gene="SPBC4C3.09"
FT                   /gene="B20341-1"
FT                   /product="Pfam-B_20341; pombe specific; predicted
FT                   N-terminal signal sequence"
FT                   /protein_id="CAA16831.1"
FT                   /translation="MNFFKRLRLHTRLLLRSKFVLISLILLLNLGLLLGIQIYRDPAFP
FT                   GSLISSAAYEFGLHKHGPYYNDNVDDLKRYTFMGLLTLPTSEHDVYFNATRVLVYKLKH
FT                   HPETKSKYPVHVLVMKGVDEWKIERLRLDGAEIIMVDQIKTEDLIESGLSIGMGSYRYQ
FT                   YMFTKLSVFEQTQFDKVCILDSDLLVLKNMDDIFDTPYVYESPAEPDMFSFPIFKKPDD
FT                   EEDYQFSDNFDAYGAPRSEFYPYLLGACDDRNPGHATPPEESETFNAGLMLVHPSSLHM
FT                   HRIKKIARYPYMYDDARMMEQSLLNLAYNKYGWFPWTRLDFSYNGVWVTEEDLPYLRAA
FT                   HGKFWEYDNTEFPQILTAEWHKAFGELLAFHDYVVE"
FT   CDS             complement(6433..7551)
FT                   /db_xref="GOA:O43061"
FT                   /db_xref="SPTREMBL:O43061"
FT                   /note="SPBC4C3.08, len:372, SIMILARITY:Schizosaccharomyces
FT                   pombe, YA0C_SCHPO, hypothetical 43.7 kD protein c5h10.12c
FT                   in chromosome i., (371 aa), fasta scores: opt: 857, E():0,
FT                   (41.4% identity in 292 aa)"
FT                   /note="also similar to adjacent sequence SPBC4C3.09
FT                   putative duplication"
FT                   /gene="SPBC4C3.08"
FT                   /gene="B20341-2"
FT                   /product="Pfam-B_20341; pombe specific; predicted
FT                   N-terminal signal sequence"
FT                   /protein_id="CAA16830.1"
FT                   /translation="MRLYFSAFRHPKRLGLCLLITLSIILLGWQCVLLYNHSPEIQRSV
FT                   YTLTGLAPSSKMAFVTMLTVRAANGENEVENTQQDWYYNSTRLLVHRLVKFKPTKSKYP
FT                   VVVLAMKGIDQWKLDQLQEDGAIVKVVDPLYAHEVVDDVNDIALLDSRWSMMFTKLRVF
FT                   EMYEYDRICFLDSDILPIKKMDKVFDVHQLSYSKDSVLFPPTLFYKPRRSIFWRRFTEE
FT                   FAAYGLTRDDLYPYVFAAVSDPGMWHETPPPFKDYFNAGLFVFKPLKAHYKRLMALARF
FT                   PKLYDNANMMEQSLLNFAYNSAGAFPWESLDWTFNGLWARKNDLPYLKAVHGKHWQPEG
FT                   SLGYDEDTSKLWWDAFQEMQTYHDQQRNADLY"
FT   CDS             complement(8045..8953)
FT                   /db_xref="SPTREMBL:O43060"
FT                   /note="SPBC4C3.07, len:302, SIMILARITY:Caenorhabditis
FT                   elegans., Q18967, d2013.7 protein., (294 aa), fasta scores:
FT                   opt: 383, E():5.9e-18, (26.2% identity in 294 aa)"
FT                   /gene="SPBC4C3.07"
FT                   /product="Mov34 domain protein; putative COP9/signalosome
FT                   complex subunit 6; no apparent S. cerevisiae ortholog"
FT                   /protein_id="CAA16829.1"
FT                   /translation="MALGTKHVLHLTKPSSRSSPLNIVIEPAVLFSILDHSTRKSENNQ
FT                   RVIGTLLGTRSEDGREIEIKSCFAVPHNESSEQVEVEMEYHRAMYHLHLKANPREVVVG
FT                   WYATSPDLDAFSALIQNLYASPAEPGTAPLGTYPHPCVHLTVNTDVSSPLAIKTYVSSP
FT                   VGITERLADSCAFVPTPFTIRDDEAVRSGLKAVAAPKNDPSRLASLFTDLQQLRRSTLE
FT                   LLSMIERVSDYVQNVIDGSSPANVAVGRYLMKCFSLIPCVEGQDFEKIFSSHLQDVLVV
FT                   VYLANTLRTQVDIASRLNLLP"
FT   misc_feature    complement(8057..8893)
FT                   /note="Match to PF01398 Mov34, Mov34 family Score 165.25"
FT   CDS             join(complement(11807..11848),complement(9351..11765))
FT                   /db_xref="SPTREMBL:O43059"
FT                   /note="SPBC4C3.06, len:818, SIMILARITY:Saccharomyces
FT                   cerevisiae, YCS0_YEAST, hypothetical 96.1 kD protein, (870
FT                   aa), fasta scores: opt: 204, E():8.4e-05, (21.6% identity
FT                   in 886 aa)"
FT                   /gene="SPBC4C3.06"
FT                   /product="hypothetical protein; similar to S. cerevisiae
FT                   YCR030C"
FT                   /protein_id="CAA16828.1"
FT                   /translation="MESLTKTEYVDAFLSNYSPNDSMSIFRQRLEQVRLDNDMLSQWIR
FT                   ERMDIERQYSDQLHKLAMNMQEKNNSSFAFNYAWKQLEGETLEISRYHSQIIGQIASQV
FT                   YKPLIDYYTSSPQTATLRRLAERLSTVAEEMASSSVPGLKGLKKKGRDADTKSQNDLTA
FT                   SRATWDSDAPLAFEKLQIVDEERLLILKQVYLTIASLETDTALKQQEFFSKSMAVYSDL
FT                   PIEGEIRQFMNSTSKVMSSASANKPSKSSGFHINNGKSKEEKSHGENESGGKLKNKMST
FT                   LFRRKTIMPKKDKKPSHKSNGRPNKLTAFFNKNSKASSISSAEEHPSNIDDSSIERRHY
FT                   DSNHSSQIRDHPSTNNNASSYQNFNETSDEGEDNDATIRANNVRSSFLEAPLPVQPNVQ
FT                   AETVTPKISSKASPFNKPNSVHSEASRNTPSSIDRENASHSNPIMMHGNDFGGNFNNMQ
FT                   SRSTTTSPTSAVASPAPTENEDSNAAIERVANTLRKNPTISRRTRRAGTMDRYATASSD
FT                   YMESNLGSLPNLSTLSLQSGPDSTATWHPEFPNSSGLSASIVEKYSGELSEDGLLHPSC
FT                   SGHIFMKYTSDFNTPPPEMGVRVASEFPMSFTHLNDHAVKYGPSENTLSLIPELLLSPI
FT                   KVTDFNLHLDSINGASCIPLTVVQKWKHDESSSSMIAFVKPNPVWRNLGSSLHIEKLVI
FT                   IVYLGENVLVKSCQSSPAGEFSRKTSKLKLHLSNINISSSGFKILAKFAISPSAAIRKP
FT                   VIEFRIRMVDSSNNPGLTKLFLKPDMFDTTSSSGGSQLESAYEETKVPTSYGIHVRECS
FT                   VFADMS"
FT   misc_feature    complement(11766..11776)
FT                   /note="ttaacaaatag, splice branch and acceptor"
FT   misc_feature    complement(11801..11806)
FT                   /note="gtaagc, splice donor sequence"
FT   CDS             13046..18115
FT                   /db_xref="GOA:P15398"
FT                   /db_xref="SWISS-PROT:P15398"
FT                   /note="SPBC4C3.05c, len:1689"
FT                   /gene="nuc1"
FT                   /gene="SPBC4C3.05c"
FT                   /EC_number="2.7.7.6"
FT                   /gene="rpa1"
FT                   /product="DNA-directed RNA polymerase I 190 kD subunit"
FT                   /protein_id="CAA16827.1"
FT                   /translation="MNIAQPVSSEIKSVKFGIYDVDDVEKISVKQIVNPVLLDNLNHPT
FT                   NGGLYDLALGPYLKNSVCATCHLDERYCPGHFGHIVLPIPAYHPLFFSQMYNLLRSTCL
FT                   YCHHFKLSKVKVHLFFCRLKLLDYGLLNESEMVENVSLTEAIIKNSNGTPLEDGSDSED
FT                   SGLGHDDIAKDAATLMRIRDEFVAKSIADSRQNAHIDAQLTTLLLHERKKVVRAFYHAI
FT                   SSRKQCDNCQSFSPNFRKEGFAKIFEIPLSGKNLQFMEQTGKIRSDVLRDTSKKHHEDE
FT                   GYDGDSDSSNESEVEGIDLFEEDPNPLKNKSKSPIAHGAKYMTSTEVRNHLRRLFVKEN
FT                   VVLSRLYAHKRGKPASADMFFLQNIAVPPTRFRPASKMGDEVHENIQNELLTRILQSSI
FT                   QIASLSKDSTVEVNPDEKEGLERRSRAFELLINAFVQLQHDVNSLIDSNRNPSSGGQSR
FT                   TVPPGIKQILEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFATKLTYPE
FT                   PVTLYNFNEMRNAVINGPHKWPGASHIQNEDGTLISLMPLTIEQRTALANQLLTPQSNL
FT                   ISSPYSYSRLINTNKKVYRHVRNGDMLILNRQPTLHKPSMMAHKARILPGEKTIRMHYA
FT                   NCNSYNADFDGDEMNMHFPQSTNARSEAQFIANTDSQYLVPTSGDPLRGLIQDHVVMGV
FT                   WLTCKDTFYTRDEYQQLLFQALKPDETGMYGRIKTLPPAIQRPGIYWTGKQIISSVLLN
FT                   LKPSDRPGLNLKSKAKVPGKYWSPDSEEGSVLFDDGELLCGILDKSSFGASAFGLVHSV
FT                   HELYGPDIAGRLLSVLSRLFTAYAQMRGFTCRMDDLRLDEQGDNWRRQLLENGKSFGLE
FT                   AASEYVGLSTDSPIALLNANLEEVYRDDEKLQGLDAAMKGKMNGLTSSIINKCIPDGLL
FT                   TKFPYNHMQTMTVSGAKGSNVNVSQISCLLGQQELEGRRVPLMVSGKSLPSFVPYETSA
FT                   KSGGFIASRFLTGIAPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLMKHLEGLCVQYD
FT                   HTVRDSDGSIVQFHYGEDSLDVTKQKHLTQFEFSAKNYKSLIQKYKVKSVLSAVDSETA
FT                   SSYAKKALKKPYKYDPVLDKYPPSRYLGSVSEKFQRAVDEYTQKNPDKLIASKKESKLD
FT                   DSLLNESKFKALMQLRYQQSLVDPGESVGVLASQSIGEPSTQMTLNTFHFAGFGAKNVT
FT                   LGIPRLREIIMTASANIQTPTMTLRLNDGVSDKRASAFCKEVNKLVLSEVVRQVRVTEK
FT                   ISGQGSDEQSKTYAIRLDLYSRDEYQDEYGVLQEEIESTFSNRFLKILNRIIKSYLAKS
FT                   KQRKSGGKDDTVPEVGQALKPLEDIDEAPIEGRAQEALEDEDNDATNEKMVSRSKQHAS
FT                   YEGPDEADKVALRQLKGSNKVEDVNMDEEEDEGFKSDESVSDFKERKLLEKQNTVSISE
FT                   RRELQLKTAKEILSNCKHLDFDYVNGEWATVELVFPINTEKLLMVSLVEKACSETVIHE
FT                   IPGITRCFSKPPDSALDTVPKVITEGVNLKAIWEFYNEISMNDIYTNDIAAILRIYGVE
FT                   AARNAIVHEVSSVFGVYGIAVDPRHLSLIADYMTFEGGYKAFNRMGIEYNTSPFAKMSF
FT                   ETTCHFLTEAALRGDVDDLSNPSSRLVVGRVGNFGTGSFDIFTPVVDSPAN"
FT   misc_feature    13232..13249
FT                   /note="PS00190 Cytochrome c family heme-binding site
FT                   signature"
FT   misc_feature    13352..13369
FT                   /note="PS00190 Cytochrome c family heme-binding site
FT                   signature"
FT   misc_feature    14117..16243
FT                   /note="Match to PF00623 RNA_pol_A, RNA polymerase alpha
FT                   subunit Score 1213.39"
FT   CDS             complement(18642..20633)
FT                   /db_xref="GOA:O43058"
FT                   /db_xref="SWISS-PROT:O43058"
FT                   /note="This gene was originally given the ID SPBC4C3.05c,
FT                   but this caused confusion as we also had a SPBC4C3.05c. On
FT                   the 18. October this was renamed as SPBC4C3.12 the next
FT                   available name space for this cosmid"
FT                   /gene="sep1"
FT                   /gene="SPBC4C3.12"
FT                   /product="fork head domain; transcription factor; involved
FT                   in the regulation of cytokinesis; involved in the
FT                   regulation of septation"
FT                   /protein_id="CAA16826.1"
FT                   /translation="MNFNSTNPYYFTHEKNLNNASKYSELPIAYQEIPLQSLPPYPKVA
FT                   SKLKGVVAGGKENNIASFQKPSSKATRPYIPSYTRLTYSVPPLPIPPPSEQSLDTIIYR
FT                   NPSVSSSQSQEPEEFFLPLDDGKKPPYSYAMLIGMSIIRSPDRRLTLSAIYDWISNTFS
FT                   FYNKSNNGWQNSIRHNLSLNKAFMKIERPRNLPGKGHFWSIRPGHEEQFLKLKLRKPGV
FT                   NSRPAPPVQDVTSSTKYGSSTGSSGFNTFNTSPHIFNQRHQYLQNYYTASLTNIPTISN
FT                   VNATNFHPLHSQQPYVDTPGIDAPSDLEAKFSDLGVSSVVSVTSPLQSCTNSPSPPLSS
FT                   PASSASPSESLRNESLGIKSAKSLGLNKDDAPVEGPPVSHLEKDVETPSVHDSVLGFND
FT                   TVTNLGKKGLKDGTTNTLQIPAVRLPSLPSSPTIKNPSGLLLKRSNSIDFPTPPKALCP
FT                   KLFCFRDDIVADDYTKFSLLSPIRSDMSGISASPNTNLKEHRTRILQMLATPDAKQLSS
FT                   LTSSDAEFWSVTPLKSSILRNGDASKQVTLSESPKGDSLLDGGSLSYFTNNISSVAGLE
FT                   TPSKLPMSKSFDTFEDDFLDPMDMLSFENHFSDFNSNRKVSPVKREVRRKYISSATTIH
FT                   SSAAQDDTYLPSPTKRKMPLLRQTSTLF"
FT   misc_feature    complement(19977..20252)
FT                   /note="Match to PF00250 Fork_head, Fork head domain Score
FT                   167.46"
FT   misc_feature    complement(20100..20120)
FT                   /note="PS00658 Fork head domain signature 2"
FT   LTR             21406..21667
FT                   /note="208 (+1) 74 330 TF1"
FT   CDS             22753..23055
FT                   /db_xref="GOA:O43057"
FT                   /db_xref="SWISS-PROT:O43057"
FT                   /note="SPBC4C3.04c, len:100, SIMILARITY:Homo sapiens,
FT                   MSS4_HUMAN, guanine nucleotide exchange factor mss4, (123
FT                   aa), fasta scores: opt: 181, E():6.5e-07, (34.7% identity
FT                   in 101 aa)"
FT                   /gene="SPBC4C3.04c"
FT                   /product="putative guanine nucleotide exchange factor;
FT                   putative yeast dss4 homolog-Guanine-nucleotide exchange
FT                   factor for Sec4p"
FT                   /protein_id="CAA16825.1"
FT                   /translation="MSNLRIVCQHCPSVVFNNKRPDVVKRPTMSAMLHSETQEDLETDD
FT                   FFLLKDPFAFDNVSVSKPLANNYKLLACADCEKGPLGYYDSKNNEYLLLCSLEKN"
FT   CDS             complement(23698..24714)
FT                   /db_xref="GOA:O43056"
FT                   /db_xref="SWISS-PROT:O43056"
FT                   /note="Pfam match to entry GHMP_kinases PF0028 8, GHMP
FT                   kinases putative ATP-binding proteins"
FT                   /note="SPBC4C3.03, len:338, SIMILARITY:Saccharomyces
FT                   cerevisiae, KHSE_YEAST, homoserine kinase, (356 aa), fasta
FT                   scores: opt: 1074, E():0, (53.1% identity in 354 aa)"
FT                   /gene="SPBC4C3.03"
FT                   /EC_number="2.7.1.39"
FT                   /product="putative homoserine kinase"
FT                   /protein_id="CAA16824.1"
FT                   /translation="MQKFQIKVPASSANIGPGFDVLGMSLEEYMTLDVEVSTESGPCVL
FT                   TYEGDGKEHVSLDVQKNMITQTSLYVLRCNNISTFPYATKIHVINPIPLGRGMGSSGSA
FT                   AIAGVMLANEIAKLGLSKLQMMDYVLMIERHPDNVMASMMGGFVGSFLRELSEEEKNAF
FT                   SPSADDLLKNEALTLPPKSLGTFARLPWASELKAIVVIPEFHLATSKARSVLPTSYGRT
FT                   DVVYNLQRLALLTTALGQTPINPHLVYEVMKDKVHQPYRASLIPGLQNILATLNPDTQP
FT                   GLCGICLSGAGPTVLALATGNFDEIAHAMLSIFEKHGVKCRYLVLSPAFDGATVKYF"
FT   misc_feature    complement(24301..24513)
FT                   /note="Match to PF00288 GHMP_kinases, GHMP kinases putative
FT                   ATP-binding proteins Score 49.01"
FT   CDS             25869..28235
FT                   /db_xref="GOA:P20772"
FT                   /db_xref="SWISS-PROT:P20772"
FT                   /note="SPBC4C3.02c, len:788"
FT                   /gene="ade1"
FT                   /gene="SPBC4C3.02c"
FT                   /gene="SPBC405.01"
FT                   /product="bifunctional purine biosynthetic protein
FT                   ade1-includes:phosphoribosylamine--glycine ligase"
FT                   /EC_number="6.3.3.1"
FT                   /gene="min4"
FT                   /protein_id="CAA16823.1"
FT                   /translation="MEPIIALLIGNGGREHTIAWKLCESPLISKVYVAPGNGGTASNGA
FT                   ESKMENVNIGVCDFEQLVKFALDKDVNLVIPGPELPLVEGIEGHFRRVGIPCFGPSALA
FT                   ARMEGSKVFSKDFMHRNNIPTAVYKSFSNYDHAKSFLDTCTFDVVIKADGLAAGKGVII
FT                   PKTKKEAFEALESIMLNEEFGSAGKNVVIEELLEGEELSILTFSDGYTCRSLPPAQDHK
FT                   RAFDGDKGPNTGGMGCYAPTPVASPKLLETVQSTIIQPTIDGMRHEGYPLVGILFTGLM
FT                   LTPSGPRVLEYNVRFGDPETQAVLPLLESDLAEIILACVNHRLDAIDIVISRKFSCAVV
FT                   CVAGGYPGPYNKGDIITFDALKDKNTRIFHAGTSIRDGNVVTNGGRVLAVEATGDSVEA
FT                   AVRLAYEGVKTVHFDKMFYRKDIAHHALNPKRKTREILTYENSGVSVDNGNEFVQRIKD
FT                   LVKSTRRPGADADIGGFGGIFDLKQAGWNDPLLVSATDGVGSKLLIALSLNKHDTVGID
FT                   LVAMNVNDLVVQGAEPLIFLDYFATGSLDLKVSTSFVEGVVKGCKQAGCALVGGETSEM
FT                   PGLYHDGHYDANGTSVGAVSRDDILPKPESFSKGDILLGLASDGVHSNGYSLVRKIVEY
FT                   SDLEYTSVCPWDKNVRLGDSLLIPTRIYVKPLLHVIRKNIVKGMAHITGGGLVENVPRM
FT                   LPSHLNAIIDVDTWEVPEVFKWLKDAGNVPISDMARTFNMGIGMVVAVASEDAEETMKE
FT                   LTSVGETVYRIGQLVDKESSSERCHLVNLNKWETF"
FT   misc_feature    25887..27149
FT                   /note="Match to PF01071 GARS, Phosphoribosylglycinamide
FT                   synthetase (GARS) Score 984.59"
FT   misc_feature    26751..26774
FT                   /note="PS00184 Phosphoribosylglycinamide synthetase signatu
FT                   re"
FT   misc_feature    27222..28175
FT                   /note="Match to PF00586 AIRS, AIR synthase related proteins
FT                   Score 525.45"
FT   misc_feature    27677..29767
FT                   /note="nominal overlap with cosmid SPBC405, EM:AL021730 S.
FT                   pombe chromosome 2"
FT   CDS             complement(28613..29767)
FT                   /codon_start=1
FT                   /db_xref="GOA:Q9UUM6"
FT                   /db_xref="SPTREMBL:Q9UUM6"
FT                   /note="SPBC4C3.01,  len:<384aa"
FT                   /partial
FT                   /gene="SPBC4C3.01"
FT                   /gene="SPBC405.02c"
FT                   /product="hypothetical protein; sequence orphan"
FT                   /protein_id="CAA16822.1"
FT                   /translation="DRPQFHRADSTVTEQSSEILFDGNAESAEPLSKRSPPFLAYTPKR
FT                   AVSATLATTQSSPISTSFNPQLPSNSNTNRFDFGSESQLSSNYTNDTGLSLLSLPKSVP
FT                   HSPAMHKRTPSSDPNNPFGSTFANKFLDHIPAEPLPLPARPQISDLSFFRKPSLPSALQ
FT                   NIVIEKNASQRSVSEPLHNLSSRYSHFTSPHIDDSQHFPPMEFFARSDELPNPFVPFFD
FT                   LDSKPNLSTLQDNASLTSQGSNLSSQNSGLSSSSSGIFGRMPIPAQSLDTTMLRTDSNS
FT                   NIRRATTSFIANSEKENSSNFIDPQKYASIKFKNGNGVSKFMFLFTFGIVFPPLWILAS
FT                   FLPIPRTKIHQMRVKHVHWRIINRVVACLGVAITFLFIGLGVSG"
XX
SQ   Sequence 29767 BP; 9638 A; 5181 C; 5752 G; 9196 T; 0 other;
     gatcgactca gacgatggaa ccaacttgta ataaagtctg tcaacaggca tctgatggct        60
     tcgaagtgaa gcatagccat aatgagcagt tggagcagtg aaacgattta ccgtaggaag       120
     ctcctgacgt cgagcagttt cctgatgctt tacaatggat gcagaagcaa atgccgcggc       180
     agcattagca gcagctgcgg ctgtcacatt tgagcgataa taagcaggag cattaggaat       240
     ggctatgtta taattaggcc ggaatgactg cataggagga ggatcttgag tccataaatt       300
     gtcccaagta atagtagcaa aaaaaggaaa ttgttttatt tgttgggttg tagatcgatc       360
     agatggctga atacggaaaa gatggctaaa caaaggaacg atatcaggtg gtaagagctt       420
     tggaagctca tattccaggc tcattatctt tttgaaaata ttattaggat tgctgccatg       480
     aaaaggaggg gaaccaacaa tcatttgata aacaacacac gcaaaagccc ataaatcgga       540
     acttaaatat ttgtcagaaa aaaaatagac tgggataata ggttttctta cgattttgaa       600
     acaacttgtc tagacaatag ttcaggagca acatattccg cagtgccaac aaaggagctt       660
     ggaaaggtag tgtaatcagg gctatttaca tatttagggg gtaggatttt ggctgtgccg       720
     aaatcggtaa tttttacatg catatttcca tcaaataaaa tgctaaaaaa taggttagaa       780
     ttaggaaaag gaaacgaaca tttaatgacc actactcaaa catacttttc tggcttgaga       840
     tctctgtgaa ttataccgca ggagtgcata tactcgatac ttgataaaat ctcagcagca       900
     taaaagcgca cacaattctc atcaagaaaa cgatactacc aaagcttagt taataaagga       960
     aaaatgaata gactaatgaa aaaatatacc tttttgatgt attgcaaaag ttcaccattg      1020
     ggtgcaagtt caagcacata ataaagtttt aaatcatcct gaaatgtatg gaaaagacga      1080
     gagataccag gaaacccatt aagtctcatc atagaatctc tctctatatt cacatactta      1140
     accttatttt ccttgacaat atatttttta tcaaggactt tgatagcgta ctccttccaa      1200
     ctctttttat cagttgctct tctcacctaa cgaatattag acaacttatt cgtcagtaat      1260
     cgaaggtcca taggttaatc gacctgcggt tgaaaaactt ctgaactgag aagcaatgta      1320
     tcaacttacc tttgagaatg atccatctcc tataatgtca ccaaaaacgt aatccgccgg      1380
     agatttgatc gatcctatat gacttgttcc tggtactacg ttggaagact gaggttttac      1440
     cggatttctt tcacctctag cctcgaagta atcgggatcc gcataatccg gcaatgtact      1500
     tcggctaatg cgtttatgct ccagatccat catttataaa agaggttttc atgaaaaatg      1560
     aagttgtgtt tgagttactt tacgtttgct gttcgattcc aactgaaaca ccgtgcattt      1620
     aattgtggag ttgctggcct tggagttgtg ttctgtgaag gatgtaaaca ctaagtagag      1680
     taccctattt ctccaatcct cgtcattatt acataaattt aaaacgtaga atatgccatg      1740
     taaacaataa attaaaggtc gaattgtcaa agaaaaaatg ctcattaagc agcttgatag      1800
     ccttatcata cccatcaaag tcttacatcg cattaatgat acttcgatat gacctgaaga      1860
     tggtagtaca aaaaaattgc tttgggtgtt tatagcatta gcgaaagcga tacaatttgg      1920
     aacggcaatg aaaatttttt taattcaatg ttttaagctc acgctaagct atccatggcg      1980
     atattcgctc taaaaagcaa taaattgctt gaatatgttt gaaatagttt ataaataaat      2040
     atatatatgt acatattgtt gaaataacag acacctaaac aaaagagatt tttagaaagc      2100
     cagttgtctt tgggatactg ccttactaaa ataagcaaaa tacactgtag ttaatgaaat      2160
     gcttcttgcc ttaattccaa aattaatttg gcgattaaca gaatttggaa catcccctat      2220
     cacctcaata ttgcttggaa ttctgcttcg ctagaaatga aacataacat gatacctaat      2280
     tcacagttta gaagatccgt cgtaagaaat tctcgtaaat atatatacat cattccaggt      2340
     cgaacttcca atatcttcat tttttgttaa aagatcatgg tcatattatt ttcattcttc      2400
     aatagctatg gtttttttca tgttatttgc gtaagtaaac caaatataag cagtcgtcaa      2460
     atattaagaa aacaaaatct tcagaaacct ttttagtccc aaacttttag attctttcat      2520
     tctttcctat gttaatttct agctgagcac tttcaagttc aatccatggt tataactctg      2580
     tagtcggctg taacttttga tcaaaaattt ttaatactat acccttatct atagtcgtta      2640
     aagaatttct taaaaaatat acgaattctt tcaacacttt ttacaattga ataacaattt      2700
     tttatattca tactgcaatt tcatatgcag gtagcaatgt tacctaaatt ttggctgctt      2760
     ctcaatacca tacacaagtc cctaatcatt ttaacctttc accaaacttc tgaaaatggc      2820
     cactactgtg aaagatacta tgaatgttga cattaatgct attaaaaagg ggtatgattg      2880
     cgggaaattg attttgaaag ttctgacttt gtagagaaat tcgtatgggt accaccatca      2940
     cggcgctccg ttataaagat ggcgttatac ttgctgcaga ttctcgaaca actatgggtg      3000
     tgtattggaa tatcagaact tttcgttctt tgatttctaa cgttgctagg tgcatatatt      3060
     gcaaatcgtg tcactgataa gctgactcag ctgacagaca atatttggtg ctgtcgcagt      3120
     ggttctgctg ctgatacgca aactgtggct gatcttctaa aatactatct ttccatgtat      3180
     cggtaagtta cccttgaatg aaccgaatga ctgtaaatta aggctgcttt agctggttta      3240
     tcctttagaa taaactatcg acttactctc aagtccttat gtttactaga tgattactaa      3300
     agcctttttg catgttttat ttttcatttt attgttgtta aaaaaattat ctaacgatta      3360
     tgaagtattc aatttggcca tgaccctagt gttcatacag ctgctacttt agcttctgaa      3420
     atgtgttatc aaaacaaaaa tatgcttagt gcaggtttaa ttgttgctgg atatgatgaa      3480
     aaaactgggg gagatgttta cagtattccg ttaggtggta gtttgcataa gcaaccttta      3540
     gctattggag gaagtggttc tgcttttatt tatggatttt gcgatgctaa ctttcgcgaa      3600
     aatatgaccc aagaggaggc tgttgaattt ttaaagaacg ctgttgcttt agccatggaa      3660
     cgcgatggca gcagtggtgg taccattcga atggtcattt taaataaaga tggaatggag      3720
     cgtaaatttt ttgccattga tactgctaac cctattcccg tatttactca ctaagtactt      3780
     cacgtttcct tttattttac gtgactatac tgatacccaa tgcttatgct agacttgacc      3840
     ttattaatgc ctgtctcatt atttgtagct tttggagtgc aaggtcatga agaaaagtta      3900
     cttttctggt cagtgagata agtctttgtg atgattaaaa tagaaagatt ttttatagtt      3960
     acagttaact accgaagtgt agttatattg ttgatagtga aagaatatta ttgttatgag      4020
     tcctatgtaa ttgtcataag agtaaaaatg ttgtaagatg cctgcaagca catttaaaat      4080
     tttgattatc agcttcatac aagaaaattg taatcagcca tgtaaaatat aaaattagtc      4140
     cgaacaccgg tagacccttc taaagaagaa taaaatatga tgtgtctttt tttgtttaaa      4200
     attgaatgca gaaattatgt gaaaagaaca aactttaacg gtaagaatat acacggtgag      4260
     atatgtatta agctcttcaa caggtacacc gtagttacag gtcaaggaat ggaagtggga      4320
     caaaaaaata atgaagcatg aaaacattaa agataaacgc cccccttcat tttttattct      4380
     acaacatagt catgaaaagc cagcaactct ccgaacgctt tatgccactc ggcagtcaaa      4440
     atttggggaa actccgtgtt gtcatattcc caaaatttac catgagcagc acgaagatag      4500
     ggtaagtcct cttcggtgac ccaaactcca ttatatgaaa aatcgagcct cgtccaggga      4560
     aaccaaccat atttattata agcaagattt aataaacttt gttccatcat tctagcatcg      4620
     tcatacatat aaggataacg tgctatcttc ttaatcctat gcatatgaag actactggga      4680
     tgaacaagca tcagcccggc attaaaagtt tcagattctt ctgggggcgt cgcatgtcca      4740
     gggttacgat cgtcacatgc gccaagaaga tatggataga attctgagcg aggagcacca      4800
     taggcatcga aattgtcgct aaactgataa tcctcttcat catctggctt cttaaagata      4860
     ggaaagctaa acatatcggg ttctgcagga gattcataaa catagggagt atcaaaaatg      4920
     tcatccatgt ttttcaatac taggagatcg ctatccagaa tgcagacctt atcaaactgt      4980
     gtttgctcaa atacactgag ttttgtgaac atgtattgat aacgataact gcccatgcca      5040
     atagacaaac cactttcaat taagtcttca gttttaattt gatcgaccat aattatttcg      5100
     gccccatcaa gtcgcaatcg ttcaattttc cattcatcaa cccctttcat aacaaggaca      5160
     tgaacgggat atttactttt cgtttcagga tgatgtttca gcttgtatac tagtactcga      5220
     gtagcattga agtatacatc atgttctgaa gtaggaaggg taagtaagcc cataaatgta      5280
     taccttttta aatcatctac attatcgtta taatatgggc catgcttatg aagcccaaat      5340
     tcataggctg ccgatgaaat tagcgatcca ggaaatgcgg gatcccgata tatttggatc      5400
     cctaaaagta aacccaaatt cagcaaaaga attagtgaaa tcaagacaaa ttttgagcga      5460
     agtagaagcc tggtatgtaa gcgtaaccgc ttaaagaaat tcatattcta taaagcaaat      5520
     tttatcgctt tccgcaactt cgtttatagc tataaaatcc ccaccagaat aataaaaacc      5580
     ctaggattat aactgactat atctcgttaa gacttgctag gtttaataca ataaatataa      5640
     tgtagtttgt attattgagt ttggtagtgg ctgactacaa tttaggagac taaaggtacg      5700
     atgtaatgcg tacgaagtat agtttttcat gtaaaatttt aagattattt gagtttacag      5760
     tacttgttat ttgacattaa aaggtttaaa aaatttatca attacttgct attgatattt      5820
     tctatcccat cttcactcta tctaaaacca agccttcttt gatatatata tttaaaacaa      5880
     cttttaaata gatttgctac ctaaaacatt ttcaaatgtc ttattgaaat ctaaaaatga      5940
     aaaacatgct aaggatacgt atgctcacta attagcaatt tttatataaa tccgttggtt      6000
     ttcctttggt caaagaaaaa gcatttataa catgtttgct tacaatttta aaattgatga      6060
     taggactaac acttgattct ttacactaat taggaatttt ttaagaagga gcaaaatttc      6120
     ttgaaaccat tgaactttca gtgagtttta aacatacgtg atctaatttg catacagaga      6180
     ggaagctatt tttttgatta tggtttacct gtatccagaa tcccatcgat cgtgtatatg      6240
     aatttgaata gtatagtggt tttaaaaaag gacggaggaa acacaaatta ttttagaatg      6300
     actgtaaaaa tgagatagcc tttcaacagt acgtgttgtc agcaatacat taaatgaaaa      6360
     taactgcttc ttaaaagtca aaagccgcct tattttttac ttgatcacga catgaaaatt      6420
     gctttcatct gtttaatata aatcagcatt acgttgttgg tcatgatacg tttgcatttc      6480
     ttgaaacgca tcccaccata gcttggatgt gtcttcatca taacctagac ttccttctgg      6540
     ttgccaatgt tttccatgaa ctgcttttag atatggtaag tcattttttc tagcccaaag      6600
     tccgttaaaa gtccaatcaa gtgactccca tggaaaagca cctgctgaat tgtatgcaaa      6660
     atttagcaaa ctttgctcca tcatgtttgc attatcatac aattttggaa accttgctaa      6720
     tgccattaac cttttataat gtgccttcaa tggcttaaag acgaatagac cagcattaaa      6780
     ataatcttta aaaggaggag gagtttcatg ccacatacct ggatcggaca cagcagcgaa      6840
     aacgtaggga taaagatcgt ctcttgtcag cccgtaagct gcaaactctt ctgtaaagcg      6900
     tctccaaaaa atgctgcgcc taggcttgta gaatagggtg ggaggaaaca gaacagaatc      6960
     cttactatag gagagttggt gaacatcaaa aactttgtcc atttttttaa taggcaaaat      7020
     atcactatca agaaaacata ttctatcata ttcgtacatt tcgaaaactc tcaacttggt      7080
     aaacatcata ctccatcggg aatccagtag ggcaatgtca ttgacatcgt caaccacttc      7140
     atgagcatat agtggatcga ctactttaac aatagctccg tcttcctgca attgatcaag      7200
     cttccactga tcaattccct tcatggctag cactacaacg ggatacttgc ttttcgtagg      7260
     tttaaatttg acaagtcggt gaacgagaag cctagttgaa ttataatacc aatcctgttg      7320
     cgtattttct acttcgtttt ccccattagc ggcgcgtaca gtaagcatag ttacaaatgc      7380
     catcttagaa gagggcgcca accctgtcag tgtgtaaact gacctttgta tttctggact      7440
     atgattgtat agcaaaacac attgccaacc taataaaata atgctcaagg taatcagtaa      7500
     acacagtcct agtcgtttgg gatggcgaaa agcactaaaa tataaacgca ttttaatggc      7560
     aattgattgc caaattataa aatggtggtg ctttcggaga gaattactct acatactccc      7620
     ttaatgtttg ttggtgcatc atacacattt tgcttacttt caataccaaa acaaactcaa      7680
     caccctgaaa aacaaataac ataattaaat cgactttata acgtaaaaac atcaaatgtt      7740
     taaaaattaa acaagcttac tattttaact ataagaaatg ttaagataca tgactctgac      7800
     ttaaaatttt ctcttattta ataagacgtt taacctaaac caattatagt ataatactaa      7860
     atagttaccg acaagctaag ctactcaaac tatgtcgaaa tgggtgaatg acgagataaa      7920
     gacagttgct tccactgagg gttaacagcc agtgtgaaaa aaggataaaa taacggtgac      7980
     ttgaaaaaag ggctatcgaa caactgttag aaattgtccg gattttttag gttataacaa      8040
     ttgcttaggg aagcaaatta agacgggaag caatatccac ttgagtacgt aaggtatttg      8100
     cgagataaac tacaaccaaa acatcttgaa gatgtgatga aaaaattttt tcaaaatctt      8160
     ggccttctac gcaaggaatt aaactaaagc acttcatcaa atatctaccg acagcaacat      8220
     tagcaggcga agaaccatca attacgtttt gcacataatc ggaaactctt tcaatcatag      8280
     ataaaagctc caaggttgat cttcgaagtt gctggagatc tgtgaatagg ctagcaagtc      8340
     tagatgggtc attcttagga gcagctacag ctttcaaacc agaacggact gcctcgtcat      8400
     cacgaatggt aaaaggggta gggacgaatg cacagctgtc agcaaggcgc tctgtaatac      8460
     ctactggtga agaaacgtaa gtcttgatgg caaggggact gctaacatct gtgttgacag      8520
     taaggtgaac acagggatga ggatacgttc ctagtggagc agttccgggt tcagcaggag      8580
     aagcatataa attttgaatc agtgcactga aagcatctaa atcaggagaa gtagcatacc      8640
     aaccaacgac aacttcacga gggttagcct tgaggtgtaa atggtacatc gcacgatgat      8700
     attccatttc aacttctacc tgctcactgc tctcattatg aggaactgca aaacaacttt      8760
     taatctcaat ttctcggcca tcttcagaac gtgttcccaa aagtgtaccg ataacacgtt      8820
     gattattttc acttttccgg gttgaatggt caaggataga aaaaagcact gctggttcaa      8880
     tgacaatgtt caaaggactt gacctggaag acggttttgt gagatggagt acgtgcttag      8940
     tccccaaagc cattttttaa aattttcacg ttgttggcta ctctcaggta ggtagatctg      9000
     gtattgttcc ccaatcaata ataattttac tgtactagtt tacagtctca tagaattcgt      9060
     taaattgaag acactatttt tcgcctaact tctaaggttt accatttaag aaagtgtatt      9120
     ttcagttgcg ttgaataatc taaaaaatct ccttaacaat gtctcatttg tacgtacaat      9180
     aatgagaaac tctttattca aaattctata actatttaca tttgtacatt ctctggttaa      9240
     aaatcattta tatatatata caatgttcaa aaaattcggt tagcaaaaaa gtgtaaacat      9300
     aaaacccaaa aaagcagttt gctttttctt gactaataat gaacagtaat ttaactcata      9360
     tcagcaaaaa cagagcactc acgaacatga ataccatagg aagtaggaac cttcgtttct      9420
     tcataagcac tttctagctg agaacctcca ctagaagaag tagtatcaaa catatctggt      9480
     ttcaaaaaca atttggtgag accagggtta ttagaggaat caaccatgcg aatacggaac      9540
     tcgataactg gctttctaat agcagcacta ggactaatcg caaacttggc taaaatttta      9600
     aatccagacg aagatatatt aatgttcgaa agatgtagct taagtttact agttttcctg      9660
     ctaaattctc cggccggaga actttgacag ctttttacaa ggacattttc ccccaagtaa      9720
     acgatgataa caagtttttc aatatgaaga gatgagccta agttcctcca cacaggatta      9780
     ggcttcacaa atgcaatcat actactactg ctttcatcat gcttccattt ctgaacaact      9840
     gtcaatggaa tgcaactagc accgttaata ctatcaagat gtagattaaa atcagtgact      9900
     ttgattggtg agagaagtag ctctggtatt aaagaaagtg tgttttctga gggtccatat      9960
     tttactgcat ggtcatttaa atgagtaaaa gacataggaa attcagacgc aacgcgaaca     10020
     cccatttcag gaggaggggt attaaaatcc gaggtatatt tcatgaatat atgaccggaa     10080
     caggaaggat gaagaaggcc atcttcagat aattcaccag aatacttttc gacgattgaa     10140
     gcagaaagcc cggaagaatt tgggaactca gggtgccatg ttgcagtcga gtctggtccc     10200
     gattgtaatg ataaagtaga caaattgggc aagctaccga ggtttgattc catatagtca     10260
     gacgatgctg tagcataacg atccattgtc ccagcacgac gggtccttct tgatatagtg     10320
     ggattctttc gtaaagtatt tgctaccctt tcaattgcag cattgctatc ctcgttttca     10380
     gtaggcgcag gggaagccac cgctgatgtg ggagacgttg ttgttgatcg tgattgcatg     10440
     ttgttaaagt tcccaccaaa atcattgcca tgcatcatga taggattcga atgtgatgca     10500
     ttctctctat cgatcgatga aggggtattt cttgaggctt cagagtgcac agaattgggt     10560
     ttattaaagg gggaagcctt ggaggaaatc ttaggcgtaa ccgtttctgc ttgaacatta     10620
     ggctgcacag gtagcggagc ctccaaaaag gatgagcgaa cattgtttgc acgaatagtg     10680
     gcatcgttgt cctcgccctc gtcggaagtt tcattaaagt tttgataaga cgaagcgtta     10740
     ttattagtag agggatgatc ccgaatttgt gaagaatgat tggaatcata atgtcttcgt     10800
     tcgattgaac tatcatctat attcgatggg tgttcttcag cagacgaaat actcgaagct     10860
     ttggagttct tattaaaaaa agcagttaat ttattagggc gaccattaga tttatgcgaa     10920
     ggcttcttat cctttttagg cattatggtt ttccgacgaa acaacgtgga cattttgttc     10980
     ttcaatttac caccagattc attttctcca tgactctttt cctctttaga ttttccattg     11040
     tttatgtgaa agcccgatga cttagatggt ttattagcag atgcggaaga cataactttc     11100
     gatgtggagt tcatgaattg acggatttca ccttcaatag gtagatcaga ataaactgcc     11160
     atagatttag aaaaaaattc ttgctgttta agagccgtat cagtttccaa acttgcaatt     11220
     gtcaggtaaa cttgtttcaa tataaggagg cgttcctcgt caacaatttg caatttttca     11280
     aacgctaaag gagcatcgga atcccaggtt gcacgagaag cagtgagatc attctgactc     11340
     ttagtatccg catcacggcc tttttttttt aatcccttca gaccaggtac agaagacgat     11400
     gccatctcct ctgcaactgt tgataaccgc tctgctaaac gtctaagcgt agccgtttgt     11460
     ggtgaagaag tataataatc tatcaaaggt ttataaactt gcgaagctat ttgtccaatg     11520
     atttgactgt gatatcttga aatttcaagg gtttctccct cgagctgttt ccaagcataa     11580
     ttaaaagcaa acgatgaatt gtttttttct tgcatgttca ttgcaagctt atgtaattga     11640
     tctgagtatt gccgttcaat atccattcgc tcacgaatcc actgcgaaag catgtcgttg     11700
     tctaggcgaa cttgctctag gcgctgtcga aagatcgaca tgctgtcgtt tggagagtag     11760
     tttgactatt tgttaataag aaggaaatag ctaaaataaa gcttaccaaa aacgcatcta     11820
     catactccgt tttcgtcaat gattccatgg cgtggtggtg gttagtgtag ggggaatgcg     11880
     actcgataca tgacacttta ttccaaaatt gcaaaacaaa ttgtttatgg aggatgatta     11940
     gtattgctat tagatggctg ttatgaagac ataagaaaat atttttaata aggcaaaatt     12000
     ttcatttcta catacatcaa tatcgatgtt tccgaaatat gcataaataa attaatcgat     12060
     tattaactag ttagctgctc aatactatgg attagtctca aaaatatttc aattgaaaag     12120
     tgacccaata taccaacaca tattcgaacc gcttaacgat ttctcaaaaa acacaagttt     12180
     ttgaataaaa acatataggt agtgaaatct attgaaacgt tcaatttttt taagccttca     12240
     acatacgcta atttcaaatc tgagttctca ctactattat cgcacctttt tctattcttt     12300
     cgaaaacata cgtttgagca gagaaaaagt cagtaacaac ttccatagta taaaaaagaa     12360
     ggagatatgt tcaaaaatca acaaaaaata tgaataattg ttcgtaaacc catattgtta     12420
     ccatagatga attttactaa ctagtgctta taaacgaaag ttttctttcg ctacttaagg     12480
     taagtaagca gaaaacattg agaatggctt taattcaatt aaatttaaaa atgaagagag     12540
     accaagatca gaaatcctaa cacatgttag actattaagg cactttatct gaagtgaagt     12600
     ctaataaaat gtaagcaacg aaagtcagtt gattgatacc aacattccac tcgcatacag     12660
     tacgaattct ctaaataact ccagtttatt tttattacga caatgaaacc ataatgccat     12720
     ggtttaagtg gtcaatatgt taaccgtgta acaatgaaag tacatcgtaa cgtgttagca     12780
     tcaataatcc ggttttttcg gtttgtttat aaatttaccg atgcgctaaa atatctaatt     12840
     tgtagtttac caaaaaattt tacgtgtgtt attgtatata acgcgctgta aaataagtaa     12900
     tgaagcttca cagctatgca cattgtaacg catttcaccg gactttagca aattacagtc     12960
     taaggaaatt ttcttttcat acagaaccaa ataggtctgt gggcggattg catgtgccgg     13020
     ttgtatacaa aagcaaaata gtacaatgaa tattgcacag ccagtctctt cggagattaa     13080
     aagtgtgaag tttgggattt acgatgttga cgatgtcgaa aaaatatccg tcaaacaaat     13140
     cgtaaatccc gttttgcttg acaatttaaa tcaccctact aacggcggat tatatgacct     13200
     tgctttgggt ccatatctaa aaaattctgt ttgcgctaca tgtcatttgg atgaaagata     13260
     ctgccctggt cattttggtc atatagtact tcctattcct gcatatcacc ctctattttt     13320
     ttctcaaatg tacaatttat tacgttcaac ttgcttgtac tgccatcatt tcaagctttc     13380
     aaaagtcaag gttcatcttt tcttttgtag actcaagttg cttgattatg gtcttttaaa     13440
     tgagtcagag atggtggaga atgtcagtct tactgaggca atcataaaga attctaacgg     13500
     cactccactt gaagatggaa gtgacagcga ggacagtggt cttggacacg atgatattgc     13560
     taaagatgct gcaacactta tgcgcattcg cgatgaattc gttgctaagt ctattgctga     13620
     ctcacgccag aacgctcata tcgatgctca gttgactaca cttcttttac acgagaggaa     13680
     aaaagttgtg cgtgccttct accatgccat ttcatctcgc aaacaatgtg ataattgcca     13740
     gtctttttcc cctaacttta ggaaagaagg ctttgctaaa atattcgaga ttccattgag     13800
     tggaaaaaat ctccaattta tggagcaaac cggaaaaatt cgttctgacg ttcttcgtga     13860
     tactagtaaa aagcatcatg aagatgaggg atatgatgga gattctgatt cgagtaatga     13920
     aagtgaagta gaaggaatag atctctttga agaagatcct aatcctttga aaaataaatc     13980
     aaaatctcca attgctcatg gagccaaata tatgacttct actgaagtcc gtaaccatct     14040
     tcgccgtctt tttgtaaaag aaaatgttgt cctttctcgt ctttatgctc ataaacgcgg     14100
     aaaacctgcc tctgctgata tgtttttcct ccaaaatatt gctgttcctc ctactcgctt     14160
     ccgtccagct tccaaaatgg gcgatgaagt acatgaaaat atccaaaatg aacttctgac     14220
     cagaatttta caatcctcaa tacaaattgc ttctctctct aaagactcta cagttgaagt     14280
     aaatcctgat gagaaagaag gcttggagcg tcgttctcgt gcttttgaac tgttgattaa     14340
     cgcttttgtt caactacaac acgatgtaaa cagcctgatt gatagtaata ggaatcctag     14400
     ttctggagga cagagtagaa cagtaccccc gggtattaag caaattttgg aaaagaagga     14460
     gggtcttttc cgtaagcata tgatgggtaa acgtgtgaat tatgcagcta gatctgtcat     14520
     ttcacctgac ccgaacattg aaactaatga aatcggtgtt ccgccagtct ttgctactaa     14580
     actcacatac ccagaaccag taactcttta caactttaac gagatgagaa atgcggttat     14640
     taatggtccc cataaatggc ctggtgctag tcatattcaa aacgaagacg gcactttaat     14700
     ttctttaatg cctttaacaa ttgaacaacg cactgcttta gccaaccagc ttcttacacc     14760
     tcaaagcaat ttaatatctt ccccatattc ttattctcgc ttaataaata ctaacaaaaa     14820
     ggtttatcgt catgtcagaa atggagacat gttgatattg aaccgtcaac ccacccttca     14880
     taagccttcg atgatggctc ataaagctcg tattcttcca ggtgagaaga cgattagaat     14940
     gcattacgca aattgcaact cttacaatgc tgatttcgat ggcgacgaaa tgaacatgca     15000
     ttttccacaa agtaccaatg cgcgttctga ggctcaattt attgcaaaca cagactctca     15060
     atatttggtg cctacctctg gtgatccttt gcgcggtctt attcaagacc atgtcgtaat     15120
     gggtgtttgg cttacctgta aagatacatt ttatactcga gatgaatatc agcaacttct     15180
     atttcaggct ttaaagcctg atgaaaccgg tatgtatggg cgtatcaaaa ctcttcctcc     15240
     tgccatacaa cgtccgggta tatactggac aggtaaacaa ataatatctt ctgttttgct     15300
     caacctaaaa cccagtgatc gtcctggtct taatcttaaa agcaaagcaa aggttccagg     15360
     aaaatactgg tcacctgact cagaggaggg atcagtatta tttgatgatg gtgaactttt     15420
     atgcggtatt cttgataagt cctcttttgg tgcctcggct tttggcttag ttcactcagt     15480
     tcatgaattg tacggtcctg acatcgctgg tcgcttgctt tctgttttaa gtcgtctatt     15540
     cactgcgtat gctcaaatgc ggggctttac ttgccgtatg gatgatttga gacttgatga     15600
     gcaaggtgat aattggagaa gacaactatt ggaaaacgga aaatcctttg gacttgaagc     15660
     tgccagtgaa tatgttggcc tttcaacaga ttcgccaatt gcgcttttga acgctaacct     15720
     tgaggaagtt tacagagatg atgagaagtt acaaggttta gatgctgcta tgaaaggtaa     15780
     aatgaacggg cttacttcct caattatcaa caaatgtatc cctgatggtt tacttacaaa     15840
     attcccctat aatcatatgc aaactatgac cgtttctggt gccaagggta gcaacgtaaa     15900
     cgtctcacag atttcttgtc ttttgggtca acaggaatta gaaggacgtc gtgttcctct     15960
     tatggtgagc ggaaagtcac ttccttcctt tgttccatat gaaacttctg ctaagtctgg     16020
     tggttttatt gccagcagat ttttaactgg tatcgcccct caggagtatt attttcactg     16080
     tatggctggc cgtgaaggct tgattgatac cgctgttaaa accagtcggt ctggttatct     16140
     tcagcgttgt ctgatgaagc atctggaagg tttatgtgta caatatgatc atactgttcg     16200
     cgattccgat ggatctatcg tccaattcca ttacggagaa gattctttag atgtcacaaa     16260
     acagaagcac ttgacacaat ttgagttttc agccaaaaat tataaatcct taattcagaa     16320
     atacaaggtc aaatctgtct tatcggcggt tgattccgaa actgcatcct cttacgcgaa     16380
     gaaagcgttg aaaaagccgt acaaatatga tccagtattg gacaagtatc cccctagtcg     16440
     atatttggga agcgtaagcg agaagtttca acgtgctgtt gatgaatata cccagaaaaa     16500
     tccggacaag ttgattgctt cgaagaaaga gagcaagctt gatgattctc ttcttaatga     16560
     atcaaagttc aaggcattga tgcagttacg ttaccaacag tctctggttg atcctggtga     16620
     aagtgttggt gtattagcta gtcaatcaat cggtgagcca tctactcaaa tgactttgaa     16680
     cacattccat tttgctggat tcggtgctaa gaatgtcaca ttaggtattc ctcgtttacg     16740
     tgagattatc atgaccgcta gtgcaaatat tcaaactcct acgatgactc ttcgtttgaa     16800
     tgacggcgtt tccgataaaa gagcttcagc tttttgtaaa gaagtaaata aattggtttt     16860
     atctgaagtt gttcgacaag tccgagtaac tgaaaaaatt tctggtcaag gctctgacga     16920
     acaatctaaa acttatgcta ttcgacttga tttatattct cgtgatgaat atcaggatga     16980
     atatggtgtt cttcaggaag agattgagtc gacctttagt aatagattct taaaaattct     17040
     taaccgaatt attaaaagct atttggctaa atctaagcag cggaagtcag gaggtaaaga     17100
     tgatacagta cctgaggttg gtcaggcatt aaagccactt gaagatatcg atgaagcacc     17160
     cattgaaggt cgtgctcaag aagctctcga agatgaagac aatgatgcta ccaatgagaa     17220
     aatggtctct aggtcgaaac agcatgcttc ttatgagggg cctgatgagg cagacaaagt     17280
     cgcccttcgt cagctaaaag gatcaaataa agttgaagac gtaaacatgg atgaagagga     17340
     agatgagggt ttcaagtccg atgaaagtgt ctctgatttt aaagaaagga aattgttgga     17400
     aaagcagaac acagtttcca tttcggaaag gcgggaactt cagttaaaga cagcaaaaga     17460
     aatactcagc aattgcaaac acctcgactt tgattacgtt aacggtgagt gggcaactgt     17520
     tgaattggtg ttcccaatca atactgaaaa gctattaatg gtgtcacttg tggaaaaggc     17580
     atgttccgaa actgtcatac acgaaattcc gggcattaca cgctgttttt ccaaacctcc     17640
     agactctgcc ttagacactg ttccgaaggt tatcactgaa ggtgtcaatc tgaaagcaat     17700
     ttgggaattt tacaatgaaa tctccatgaa tgatatttac acaaatgata ttgcagcgat     17760
     ccttaggata tacggtgttg aagcagctcg taatgcgatt gttcatgagg tttcctccgt     17820
     ttttggagtg tatggtattg ctgttgatcc tcgtcatctt tccttaattg cagattatat     17880
     gactttcgag ggaggataca aagccttcaa tagaatggga atagaatata acacttctcc     17940
     atttgcgaaa atgtcttttg agaccacttg tcactttttg actgaggccg ccctccgtgg     18000
     tgatgttgat gacttatcca atccttcatc tcggttagtc gttggtcgag tcggtaactt     18060
     tggcaccggt tcttttgaca tattcacccc tgtagtcgat tctcctgcaa actaaaaaag     18120
     gtatatttat tgcggttggg gaataatttt agaaaaatgt gtgttttgac aaaataaaag     18180
     attttggaaa ttaaaccttt attggctact tgttacaaaa atatataaaa taaataaatt     18240
     gggttttgga actaatactt gtcatataag ttttagatag gttaccacaa ataaaattac     18300
     gtttaatcta caactcttac ataacacaag agataaactt ctaaacgcta taagcgtata     18360
     ctatgtttac gaaatattca taaagcttta tattgctaat gtgactatta gatatgcaac     18420
     tgggagaaca attcgccgga tataaattaa aagctttcgt aaatttaaaa aaattgcgca     18480
     cgcaaatgaa caagtaacat cgggggtttg aaagtttatt aagcaaccaa ggtaaaagat     18540
     atgtgtaaaa ttaggaattc ccatagcagt ctttaactag aacgaagaaa tatcacatta     18600
     aataaagcat ggataaaaag tagataagtg ctaaaacaaa tttagaatag tgttgaagtt     18660
     tgacgaagaa gtggcatttt cctcttggta ggagaaggca agtaagtatc atcttgcgcg     18720
     gctgaagaat gaatagtagt tgctgaagaa atatattttc tacgcacctc acgtttaaca     18780
     ggagacactt ttcgattgct attaaagtcg gaaaagtgat tttcaaaact caacatatcc     18840
     atgggatcca aaaaatcatc ttcaaaggta tcaaacgact tgctcatggg tagcttgctt     18900
     ggtgtttcta agccggcaac ggaactaatg ttattggtaa aataagataa tgatcctcca     18960
     tcaagtaagc tatcaccttt aggactttca gatagcgtta cttgtttaga tgcatctcca     19020
     ttacgtagaa ttgaagactt caaaggcgtg actgaccaaa actctgcatc agatgatgtt     19080
     aaagatgata attgctttgc atcaggtgta gccagcattt gcaagatacg agttcgatgc     19140
     tccttcaaat ttgtattcgg acttgctgag ataccactca tatcagaacg gatgggtgaa     19200
     agtaaagaaa acttagtgta gtcatcagcc acgatgtcat cacgaaagca aaacaattta     19260
     ggacacaagg ccttcggggg ggttggaaaa tcaatagaat ttgatcgctt tagcaaaagt     19320
     ccactgggat tttttatggt aggcgagcta ggtaaagaag gtaaacggac tgcagggatc     19380
     tgtagggtat tagttgtacc atcttttaaa cctttcttgc cgagattcgt tacagtgtca     19440
     ttaaaaccca acacggaatc atgaactgaa ggggtttcaa catccttctc caaatgtgat     19500
     acaggtggac cttctactgg tgcatcatct ttattcaaac ccaatgattt agctgacttt     19560
     attcccaaag attcattcct aagtgattca gatggagaag cactggatgc tggtgatgac     19620
     aaaggaggag atggagaatt tgtacatgat tgtaaaggag aagttacaga tacgacagag     19680
     gaaacaccca aatcggaaaa cttagcttcc aaatcagaag gtgcatcgat accaggggta     19740
     tctacatagg gttgttgact atgaagagga tgaaaatttg tggcattaac attagagatc     19800
     gtcggaatgt tcgttaagga tgcagtataa taattctgaa gatattgatg tcgctgatta     19860
     aatatatggg gagaagtatt aaacgtgtta aatccagagg aaccggtaga agatccatat     19920
     tttgtagagg aggtaacgtc ttgaacagga ggcgctggtc ttgaatttac tcctggttta     19980
     cgcagcttta gttttagaaa ttgttcttca tgaccaggac gaatgctcca aaaatgaccc     20040
     ttccccggta aatttctagg acgttcaatt ttcatgaatg ccttatttag acttaaatta     20100
     tggcggatgg aattttgcca accgttattg gacttattat agaaagaaaa agtattgctg     20160
     atccaatcat atatagcact taaagtgaga cgacgatcgg gagaacggat tattgacatt     20220
     ccaattaaca tagcatagga ataaggaggt ttctttccat catctagggg taagaaaaac     20280
     tcctccggtt cttgagactg agaagaagat acagaagggt ttcgatatat aatagtatcc     20340
     aaagattgct ccgaaggagg aggtatggga agaggaggaa cagaataagt caatctagta     20400
     taagaaggta tatatggtcg agtggctttt gaagaaggtt tttgaaaaga tgcaatgtta     20460
     ttttcttttc cgcctgcaac tacgcccttc aactttgaag caaccttggg ataaggtggt     20520
     aaagattgca aaggaatttc ctgataagca attgggagtt cagagtactt agaagcattg     20580
     ttaaggtttt tttcatgagt aaaataataa gggttagtag aattaaaatt catgaggaag     20640
     atgttcagac aaattgaata ataaaacaaa aattaaagca ccgttagata atggcaatgc     20700
     caataataat aatgattaaa agagaaaacc aattaaggga aaataatagt aatagtgaat     20760
     actactatac tccggactta cacaaacata gattgtcagt atgcggacca aaaagaatga     20820
     agtattttgc aaaattcaaa gatttgaaaa gaattaataa taatagtact caaaggacaa     20880
     aaaaaaaatt gtccgacctt ggattctcgc actagtgtta cgacaaggca cgattccgaa     20940
     gcacaaaaaa aagaaagaaa gaaagtgtgg tgctctaaat tcacaatcct ttacaaccaa     21000
     aaataaagtc ttaagtctaa gacagaaata attatagaaa taggtattac agtataggaa     21060
     gcaaaagata caaactcaat actggatgct gtcagaaacg agagaaatgc acaacgagat     21120
     actaatattg cataaaaata ttaagatttg taatagtgat acacaatcgt gtcaaatatc     21180
     ctttcgtatc aaatgctccg aattgctcca attttggacg tttgccaaaa tatgagtgta     21240
     cgagatgaga tagaaatctc cacctcgtga aagcggatcc tctattttag tgacaatatg     21300
     tcatagagcc gaaaaatcga ttacgatgtt gggttgtgag tattttacta acagtaataa     21360
     gggtatacgt tatgatacgt taagctgcca attatcctcc ttcattaagt atgcccttaa     21420
     tttgacacat ttctggttcc atagtattaa ccatacagta aaacgttgtt ttattttttg     21480
     aggtcctata attagaaatt taaatgaaat gaggcactag tttcagttat gaaatatttt     21540
     tttagtgaat agctataata ttatcttcat actaaaatat ttaataacgt cggatgttca     21600
     tgcaacttaa atattgctat aaagagagta taagttgaag ttgagcttag tctaatcata     21660
     tcagttagtg gttgacaaat tttaggtgat taatacattt ggttaagaat caatagcatg     21720
     cgttatattt tttgtattat ttcaacaata acaataacga tgattgataa attgacttgg     21780
     cttagaaact catttagtta ataaaataat aatatttcaa tatttggaag ctaataatat     21840
     tctttgtcac ataactgaat cgagaagttc acggagctaa tcaagaatac ttctttttat     21900
     taaggattta gacaaagtaa tcatagtagc aataattcga gcaaaaatag cgtagttcta     21960
     tagatttcaa ttaaaatatt agacaattga agggatggca cacgattcct acacatttac     22020
     attgaaaatt gcaagtgcca agctaatttc ccaattttgc agtctgcaca cattcaaagt     22080
     ttgattacaa tatttctttc aatgccgtac ttctaaaatt ttagttacta gaagaaagtt     22140
     caaaaaccac tgtgtacaaa gttttagtat gtgtcaaggt tgcaacacgg aaagcaaatt     22200
     gagtagaaag aaaaaggttc tgtatttaac atagaaggat agaagaatta tgtgtccgaa     22260
     tttctaaatt tgaaaataac tactatatga accaatgcat caggcgaact gatatgtctc     22320
     gtttaacatt aagagaaaga caatattcaa gaacacatta gacgagcaaa taaaaatttt     22380
     ttgcgttttc ttttataata acttactaat tatgtggtga agtttaaata tagtgaaaac     22440
     caggccatgt taatttatga aaccaaatag catgtcaaaa aaaaagaagt tttcagcgtc     22500
     taattattga tttgcttcta tcgtcaaaat gcaaaacatt gttttccata tcttcattgc     22560
     actagacacg tcagtaccta ttttggaaat gaatgctaca tgtattgaat taaatttgaa     22620
     gaacttgtaa ttagcattta aacttttaaa agttttctct tgtattttta tttttttaat     22680
     aggttatatc cacaaaaaac gctgattggc gcttactact aactaactac caccatattg     22740
     ttttcctaaa ttatgtcgaa tttgcgaatt gtttgtcaac attgcccttc agtcgtattt     22800
     aataacaaac gtccagatgt tgttaagagg ccaacaatgt cagctatgct gcattctgaa     22860
     acacaagaag atctagaaac tgacgatttt tttcttctaa aagatccgtt tgctttcgac     22920
     aacgttagcg tatcaaaacc cttagcaaat aattataaat tacttgcttg tgctgattgt     22980
     gaaaaaggtc cgttgggcta ctatgattct aagaacaatg aatatttatt gctgtgctca     23040
     ttggagaaaa actaagctta ataataagtt tatcaaacaa ctgtgctatt tatcttggtt     23100
     atagcatatt tttgtaaacg ttacttattt gatatggaat ggtcttttcc atgtgtcttt     23160
     ttattcttta tattttttta gaagacttgc aacatggcct tacaaaagac aggtatgttg     23220
     tggtttcata ttgaatagta accacgaaat taggtatatt taaatggaat tataatgttt     23280
     gtttcttatt aaaaagttct tttgtagctt acacctttgt tgtgattaga ttttaatctt     23340
     atcgggtatt aaatgaaatt aaccttgact aaacaaaata taccttacga ttaaaccaat     23400
     gtttttttag cactaattta aaatttgaag aaagcacagt gaatgtgttg tacatataat     23460
     cagcttttgt cttcgtaatt accgatagat ataaatcgga caagagatat aatctaagag     23520
     cataaaattt tataactgta tctatatttt attcaaaaaa gaaaaaacca aaaaaaaccg     23580
     tgatattaaa taaaaaaaag gaatgataat tatatggtat aattggaatc ccaaatacat     23640
     gtaaatgctt cattcacgtg ttaatatacg gcaacgcatt attcatagtt atccaattca     23700
     aaagtatttg actgttgcac cgtcaaatgc aggtgaaaga actaaatatc tacacttgac     23760
     accgtgtttt tcaaaaatgc taagcattgc atgggcaatt tcgtcgaaat ttccggttgc     23820
     tagtgcaaga acggtaggac cagcaccaga aagacaaatg ccgcacaaac caggttgagt     23880
     gtcagggtta agagttgcaa gaatgttctg caagcctggg atcaacgaag cacgatatgg     23940
     ttggtgaact ttatccttca tcacttcata aactaaatga ggatttatgg gagtttggcc     24000
     taacgcagtt gtgagcaaag ccaagcgttg caaattataa accacatcag ttctaccata     24060
     agaagtagga agcacactcc gtgctttaga agttgctaaa tggaattcag ggattacgac     24120
     aattgccttt aattcagaag cccatggaag cctggcaaaa gtacctaaag acttgggagg     24180
     taaagttaag gcttcgtttt tcaataaatc atcagcagat ggagaaaatg cattcttttc     24240
     ttcctcagat agttctctga gaaatgaacc tacgaatcca cccatcatgg acgccattac     24300
     attgtctggg tgtctttcta tcattagaac ataatccatc atttgcagtt tggatagacc     24360
     aagttttgca atctcgtttg caagcataac acctgcaatg gcagccgatc cactagatcc     24420
     cataccacga ccgagaggaa tgggatttat aacgtgtatt ttggtagcat agggaaatgt     24480
     agaaatgttg ttgcaacgta agacatataa agaggtttgt gttatcatgt ttttctggac     24540
     atccaaggaa acgtgttcct taccgtctcc ttcatatgtc aagacacaag gtccgctttc     24600
     tgtggatact tccacatcaa gggtcatgta ttcctcaaga gacattccca agacatcgaa     24660
     accaggtcca atgttagcgg acgaagctgg aacttttatt tgaaatttct gcattctcac     24720
     aaaaaaagca aacaccacaa aagaaatgag tttgttttaa taaaaattaa atatatatat     24780
     atatatatct gttaaatagt aaaaaataat gaacggtttg acttgaagaa aaccgactct     24840
     ataatcgtac ggcttgctag aagcaggaac aagttgaaag atcgctttaa tatgcacgaa     24900
     atattttaaa aacaaggaaa aagagaaatg caaaaattac gaaaataata taaccgcgaa     24960
     ccgataattt tcaaaatatt tccagatcaa aaaaataata agtatctatt cccaacaatc     25020
     aaattgctcg taattaaaaa gtaaaaacaa taaaaaagaa aggttgataa tttgaaggaa     25080
     atgaaaaacc caaaaaagcc tcgctttcta tgaagatata ggcaaagaat agttttcgct     25140
     gccagaaagt tgcaatgttt actaccttta attcccgatt taacacgaca aaatcaccgg     25200
     acacactcaa taaaaagtta aattgtgcgc aatcaaattg ctaacaagag tgttatcgtg     25260
     cgctgaaaat gctgtgaaaa aggtaaaatt tgatgttggt aaagatttcg tgcacatcgg     25320
     gaatccccat aagcgaaccc ctaactcgaa tacgaaatta cgcactcgaa tgcctaatct     25380
     attaagttga ttttgatttg aaaagtgtca tgttacccgc actttttcgc aaaaccaact     25440
     tgaaatccgg aaaactggaa caaaatgcag tttgcagtta tatattatct atatatgtta     25500
     tataagagaa attttttttt cgccaatttt attctaatga actaccaaca caagttctgt     25560
     aatataacga attgtgctcg catctggaat gtttaattaa agaaaattaa cgcaacacta     25620
     agtactttat agaatcggag catattgaaa cgatgcagcg atattgtaca ttacaaagat     25680
     aacagtcaag attttctctt aagcagaaat tgcacgaatg gagtctagca agtaccaagc     25740
     gcgtgctaat taaaaaagcc gtttttgagc ttcttcttat tatagctgta agttttaagt     25800
     cactattttt tgcagtcagt gtgttagata ctaacttgca atggtagctt gctcgctgta     25860
     acgaaagcat ggaacccatt attgcgttgc tgattggcaa tggcggtcgt gaacatacca     25920
     tcgcatggaa actttgtgag tctcctttaa tttccaaagt ttacgtggcg cctggaaatg     25980
     gtggtactgc aagcaatgga gcggaatcta agatggaaaa tgtaaacatt ggagtttgcg     26040
     attttgagca acttgtcaaa tttgcgcttg ataaagatgt aaatcttgtc attcctgggc     26100
     ctgaactccc tttggtagaa ggtattgaag gtcattttcg tcgtgtgggt atcccatgct     26160
     ttggtccatc tgcattagct gctcgtatgg aaggtagcaa ggttttttct aaagatttta     26220
     tgcatcgaaa caatattcct acagctgtat ataagtcctt ttccaattat gatcatgcaa     26280
     aaagcttttt ggatacatgc acctttgatg tagtcatcaa agctgatgga cttgctgctg     26340
     gaaaaggtgt aatcattccg aaaactaaaa aagaagcctt tgaagcttta gaaagcatca     26400
     tgttaaatga agagtttgga tctgctggta aaaatgtggt tatcgaggag ctgttggagg     26460
     gtgaagaatt atctatcttg acattttctg atggttatac ttgtcgttcg cttcctcctg     26520
     ctcaagatca taaacgtgct ttcgatggtg ataagggtcc caacactgga ggtatgggtt     26580
     gctatgctcc tactcctgta gctagcccca aactacttga aacggtccaa tccaccatta     26640
     tacagcctac catcgatgga atgcgtcatg aaggttatcc attagtaggt attttattta     26700
     ctggattaat gcttactccc tctggccccc gtgtcttgga gtataatgtt cgttttggtg     26760
     accccgagac tcaagcagta ttaccccttt tggaatccga tttggctgag attatccttg     26820
     cctgtgtgaa ccatcgcttg gatgctatag atattgtcat ttcgcgtaaa tttagttgcg     26880
     ctgttgtttg cgttgccggt ggatatcctg gaccatataa taaaggtgat atcattactt     26940
     ttgatgccct aaaagacaaa aatactcgta tttttcatgc tggtacctca atccgtgatg     27000
     gcaatgttgt taccaatgga ggacgtgtac ttgctgtgga ggctacggga gattcagttg     27060
     aggctgctgt tagattagct tacgaaggtg tgaaaactgt tcattttgat aagatgttct     27120
     accgtaaaga tattgcccac catgctctta atcctaagag aaagacacgc gaaatcctta     27180
     cttatgagaa ttcaggcgtc tcagttgata atggcaatga atttgttcaa cgtatcaagg     27240
     atttggtcaa atctacacgt cgtcctggtg cagatgctga catcggtggt tttggcggta     27300
     tttttgacct caaacaagct ggctggaatg atccattgtt ggttagtgct actgacggtg     27360
     tcggttcaaa gttgttaatt gctcttagcc ttaataagca tgatactgtt ggaattgatt     27420
     tagtagcaat gaacgtcaat gacttggttg ttcagggtgc tgagcctttg atatttttgg     27480
     attattttgc taccggttca ttagatttga aggtttctac tagtttcgtt gaaggtgtcg     27540
     tcaagggctg taagcaagca ggttgtgctt tagtaggtgg tgagacatct gaaatgcctg     27600
     gtttgtatca tgacggacat tacgatgcta atggaacctc agttggagct gtctccagag     27660
     atgatattct tcctaaaccc gaaagtttct ctaaaggtga cattttgtta ggtcttgctt     27720
     ctgacggcgt tcattcaaat ggctattctc ttgttcgcaa gattgttgaa tatagcgatc     27780
     ttgaatatac ttctgtctgc ccttgggata agaacgttcg cttgggagat tctttgttaa     27840
     tacccactcg tatctatgtt aagccacttt tacatgtcat cagaaaaaat attgtaaagg     27900
     gtatggcaca cattactggt ggtggtcttg ttgagaacgt tccccgtatg cttcctagtc     27960
     atctcaatgc cattatagac gttgatactt gggaagttcc agaggtattc aaatggctga     28020
     aagatgctgg aaacgtacct atttcggata tggctcgtac tttcaatatg ggtatcggta     28080
     tggtggttgc tgtcgcttct gaagatgctg aagaaaccat gaaggaatta acgtccgtcg     28140
     gtgaaaccgt ttaccgcatt ggtcagcttg tggataaaga aagcagcagt gagcgttgtc     28200
     atttggtgaa cctgaacaaa tgggaaacat tttgagggaa attgtttaat ctgtaaaaca     28260
     tatatcagta ctttaagcta atttggtcgt ttttggattt taagttcttt ttcatttaat     28320
     aaattgatgg acttattgta tgtgtataag gtttttccat tctttactca gaacgttgtg     28380
     tatattctaa caaaaactta agtaactaca ttattatatc caataatatc cactaaataa     28440
     atcgaatgct gtaaaaaaaa ataatattac tgtactcgcc ttaaacatca atatgtttta     28500
     gtagagataa gtgctatgca gatataaggc taatacttat ataagcaatc tgttcatatt     28560
     caaataatgt gtagttagat agacaattgc aattgatcgt ttcacctaac tattaaccag     28620
     aaacgccgag accaataaat aggaatgtga tagctacgcc gaggcatgca actacacgat     28680
     tgataattct ccaatgaaca tgtttaaccc tcatttgatg tattttggtc cgaggaatgg     28740
     gaagaaaaga agctaatatc cacaacgggg gaaatacaat tccaaaagta aacaaaaaca     28800
     taaatttcga tacaccattt ccattcttaa acttgataga agcatatttc tgtggatcga     28860
     taaaattaga ggaattttct ttttctgaat ttgcaataaa ggatgtcgtt gctcgacgaa     28920
     tgtttgaatt cgaatcggtc cgtaacatag tggtgtctaa tgactgtgca ggtattggca     28980
     ttcgaccgaa tatcccggaa gaagaagaac ttaaaccaga gttttgtgaa cttaaattgc     29040
     tcccttgaga agttaacgaa gcattatctt gtaaagttga gagattaggt ttcgagtcta     29100
     agtcaaaaaa ggggacaaag gggttgggta actcgtctga tcttgcaaaa aattccatag     29160
     gaggaaaatg ctgagaatcg tctatgtgag gagaagtgaa atgactgtat cttgaagaca     29220
     agttgtgcaa aggctcggat acacttcttt gagaagcatt tttctctatg actatatttt     29280
     gtagcgcact cggtaatgaa ggcttccgaa aaaaagagag atctgagatt tgtggtctcg     29340
     caggtaaagg caaaggttca gctgggatat gatctaagaa tttgttagca aatgttgaac     29400
     caaaggggtt attaggatct gaagaagggg ttcttttgtg catggctggg ctatgcggta     29460
     cactttttgg caaggataaa agggataaac cagtgtcatt agtgtaattt gatgatagtt     29520
     ggctctcaga cccaaaatcg aatcgattag tatttgaatt ggagggcaat tggggattaa     29580
     atgatgttga gattgggcta ctttgagttg ttgctaaagt agctgacact gcccttttgg     29640
     gagtataagc tagaaacgga ggagatctct ttgagagagg ttctgcagat tctgcattac     29700
     catcaaacaa tatctcacta gattgctctg ttaccgtact gtcggcacga tggaactgtg     29760
     gacgatc                                                               29767
//