ID SPBC405 standard; DNA; FUN; 14425 BP. XX AC AL035655; XX SV AL035655.1 XX DT 11-MAR-1999 (Rel. 59, Created) DT 04-APR-2000 (Rel. 63, Last updated, Version 3) XX DE S.pombe chromosome II cosmid c405. XX KW 60s ribosomal protein l36; ade1; KW dna-directed rna polymerase ii largest subunit; dnaj related protein; KW phosphoribosylamine--glycine ligase; ras-related protein; rpl36-2. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-14425 RA Seeger K., Harris D., Wood V., Rajandream M.A., Barrell B.G.; RT ; RL Submitted (02-MAR-1999) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk XX DR GOA; O94654; O94654. DR GOA; O94655; O94655. DR GOA; O94656; O94656. DR GOA; O94657; O94657. DR GOA; O94658; O94658. DR GOA; P20772; P20772. DR GOA; Q9UUM6; Q9UUM6. DR SPTREMBL; O94654; O94654. DR SPTREMBL; O94656; O94656. DR SPTREMBL; O94657; O94657. DR SPTREMBL; Q9UUM6; Q9UUM6. DR SWISS-PROT; O94655; YPT7_SCHPO. DR SWISS-PROT; O94658; R36B_SCHPO. DR SWISS-PROT; P20772; PUR2_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c405 is overlapped at the 5' end by cosmid c1778 CC and at the 3' by cosmid c609. XX FH Key Location/Qualifiers FH FT source 1..14425 FT /chromosome="II" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c405" FT /map="IIR" FT CDS 1..559 FT /codon_start=2 FT /db_xref="GOA:P20772" FT /db_xref="SWISS-PROT:P20772" FT /label=ade1 FT /note="SPBC405.01, len:186" FT /partial FT /gene="ade1" FT /gene="SPBC4C3.02c" FT /gene="SPBC405.01" FT /product="phosphoribosylamine--glycine ligase" FT /protein_id="CAB38600.1" FT /translation="PESFSKGDILLGLASDGVHSNGYSLVRKIVEYSDLEYTSVCPWDK FT NVRLGDSLLIPTRIYVKPLLHVIRKNIVKGMAHITGGGLVENVPRMLPSHLNAIIDVDT FT WEVPEVFKWLKDAGNVPISDMARTFNMGIGMVVAVASEDAEETMKELTSVGETVYRIGQ FT LVDKESSSERCHLVNLNKWETF" FT misc_feature complement(1..2091) FT /note="nominal overlap with SPBC4C3 S. pombe chromosome 2" FT misc_feature 2..499 FT /note="Match to PF00586, AIR synthase related proteins" FT CDS complement(937..2280) FT /db_xref="GOA:Q9UUM6" FT /db_xref="SPTREMBL:Q9UUM6" FT /label=SPBC405.02c FT /note="SPBC405.02c, len:448" FT /gene="SPBC405.02c" FT /gene="SPBC4C3.01" FT /product="hypothetical serine-proline rich protein" FT /protein_id="CAB38601.1" FT /translation="MTFENLGGHAQRRDESAYRLGEEDGRQKGESSRKKRPPLSRKNPS FT NVSFWSNEPIIRHSSVKTDRPQFHRADSTVTEQSSEILFDGNAESAEPLSKRSPPFLAY FT TPKRAVSATLATTQSSPISTSFNPQLPSNSNTNRFDFGSESQLSSNYTNDTGLSLLSLP FT KSVPHSPAMHKRTPSSDPNNPFGSTFANKFLDHIPAEPLPLPARPQISDLSFFRKPSLP FT SALQNIVIEKNASQRSVSEPLHNLSSRYSHFTSPHIDDSQHFPPMEFFARSDELPNPFV FT PFFDLDSKPNLSTLQDNASLTSQGSNLSSQNSGLSSSSSGIFGRMPIPAQSLDTTMLRT FT DSNSNIRRATTSFIANSEKENSSNFIDPQKYASIKFKNGNGVSKFMFLFTFGIVFPPLW FT ILASFLPIPRTKIHQMRVKHVHWRIINRVVACLGVAITFLFIGLGVSG" FT CDS complement(3101..4126) FT /db_xref="GOA:O94654" FT /db_xref="SPTREMBL:O94654" FT /label=SPBC405.03c FT /note="SPBC405.03c, len:342, SIMILARITY:Saccharomyces FT cerevisiae, YMB8_YEAST, hypothetical 43.7 kd protein in FT ost6-psp2 intergenic region., (393 aa), fasta scores: opt: FT 685, E():0, (40.7% identity in 356 aa)" FT /gene="SPBC405.03c" FT /product="hypothetical protein similar to yeast YML018C" FT /protein_id="CAB38602.1" FT /translation="MVLQAIGKHALGVVLLLFVVFLWLISSFLTSSLLDDDNFFSPFLI FT TYINTGTFVFYLIPWYFSEKKTRKHRLMSELSMYESVHDSSFNLGTRPNSPLGFRQTAY FT LSLGFCIIWFAANYFSNSSLGFTNVASFTIISSMSGFFTLGLGTIVNVERFTLSKLLAL FT MASVGGVIIVVTQDAKQADLNDSPPSRPALGNAYALLAALLYGCYSVMVKFHITEESCV FT STRLFFGLVGLFDLILLWPFLIILHLYGVERFSLPSTTAGLIVLIINASITFVSDYLWV FT IAMLMTSPLLVTVGMSLSIPLALFFDILLKGHYLNFSLILGSLLVFAGFIVVNYNQQNI FT I" FT misc_feature complement(3668..3706) FT /note="PS00693 Riboflavin synthase alpha chain family FT signature" FT CDS join(complement(5621..5701),complement(5224..5547), FT complement(4949..5161)) FT /db_xref="GOA:O94655" FT /db_xref="SWISS-PROT:O94655" FT /label=ypt7 FT /note="SPBC405.04c, len:206, SIMILARITY:Canis familiaris, FT RAB7_CANFA, ras-related protein rab-7., (207 aa), fasta FT scores: opt: 916, E():0, (65.6% identity in 209 aa)" FT /gene="SPBC405.04c" FT /gene="ypt7" FT /product="rab protein; involved in endocytosis" FT /protein_id="CAB38603.1" FT /translation="MAGKKKHLLKVIILGESGVGKTSIMNQYVNRKFSKDYKATIGADF FT LTKEVLVDDKVVTLQLWDTAGQERFQSLGVAFYRGADCCVLVYDVNNSKSFETLDSWRD FT EFLIQASPSNPETFPFILLGNKVDVEEQKRMVSKSKALAFCQARGEIPYFETSAKEAIN FT VQEAFETVAKLALENMDSDDIAADFTDPIHLDMESQKTSCYC" FT misc_feature join(complement(5621..5674),complement(5224..5547), FT complement(4952..5161)) FT /note="Match to PF00071, Ras family" FT misc_feature complement(5162..5174) FT /note="ctaataatttcag, splice branch and acceptor" FT misc_feature complement(5218..5223) FT /note="gtatgt, splice donor sequence" FT misc_feature complement(5548..5565) FT /note="ttgaccaaatctgtttag, splice branch and acceptor" FT misc_feature complement(5615..5620) FT /note="gtatgt, splice donor sequence" FT CDS 6223..6654 FT /db_xref="GOA:O94656" FT /db_xref="SPTREMBL:O94656" FT /label=SPBC405.05 FT /note="SPBC405.05, len:144" FT /gene="SPBC405.05" FT /product="hypothetical protein." FT /protein_id="CAB38604.1" FT /translation="MELIKKIQDRDAAEKAYYDVIEPYSELLEFSFHKEFVSEEKVTQR FT TASSDSLNTIASENNDENVINLEEFRQLKRNCDLYQRNLQKLQLLFKQQSQKNTLLEKQ FT LSLQTELNQEKDKRVKILQDELWALQLEVAALERKSPNA" FT CDS 8229..9470 FT /db_xref="GOA:O94657" FT /db_xref="SPTREMBL:O94657" FT /label=SPBC405.06 FT /note="SPBC405.06, len:414, SIMILARITY:Homo sapiens, FT O60884, dnaj protein., (412 aa), fasta scores: opt: 997, FT E():0, (38.7% identity in 408 aa)" FT /gene="SPBC405.06" FT /product="dnaj related protein." FT /protein_id="CAB38605.1" FT /translation="MVVDTKLYDILEVHFEASAEEIKKSYKRLALLHHPDKAPIHEKEE FT AAERFRGVQEAYDILKDPESREMYDMYGMNSDSNSQFDGGVNLDDVLAQMFGMNFEAGG FT PGKNVPRDRKRRGSDVIHDYEISLEDMFKGKEVKLRATRNTLCPRCQGRGGKRFAKEKP FT CLSCDGKGVKQHLKHVGPHHVTNSQVICDTCNGKGVSFRGKDRCKHCKGSGTVPEQRML FT SFFVNRSAKENDKIIQRGMADEAYGITPGDVILQLHQKPHPVFERLGDDLKAKLKISLA FT EALTGFNRVILTTLDGRGLEYVQPIGKILHPGDCLIIPGEGMYKDSKTDLRGDLYLEVD FT IEFPKDGLIGTTEIEILRDILPSIPKVSVMDDTLIDSVRGVPGDISHFGGDARYANEDY FT GDETYEGVPECQAQ" FT misc_feature 8244..8447 FT /note="Match to PF00226 DnaJ domain" FT misc_feature 8628..8891 FT /note="Match to PF00684, DnaJ central domain (4 repeats)" FT misc_feature join(10970..11194,11270..11341) FT /note="Match to PF01158, Ribosomal protein L36e" FT CDS join(10973..11194,11270..11347) FT /db_xref="GOA:O94658" FT /db_xref="SWISS-PROT:O94658" FT /label=rpl36 FT /note="SPBC405.07, len:100" FT /gene="rpl36-2" FT /gene="SPBC405.07" FT /product="60s ribosomal protein l36" FT /protein_id="CAB38606.1" FT /translation="MAPGLVVGLNKGKTLTKRQLPERPSRRKGHLSKRTAFVRSIVREV FT AGFAPYERRVMELIRNSQDKRARKLAKKRLGTLKRAKGKIEELTSVIQSSRLAH" FT misc_feature 11195..11200 FT /note="gtaagt, splice donor sequence" FT misc_feature 11256..11269 FT /note="ctaacaggttttag, splice branch and acceptor" FT misc_feature 14327..14425 FT /note="nominal overlap with cosmid SPBC609, EM:AL035226 S. FT pombe chromosome 2" XX SQ Sequence 14425 BP; 4820 A; 2442 C; 2614 G; 4549 T; 0 other; acccgaaagt ttctctaaag gtgacatttt gttaggtctt gcttctgacg gcgttcattc 60 aaatggctat tctcttgttc gcaagattgt tgaatatagc gatcttgaat atacttctgt 120 ctgcccttgg gataagaacg ttcgcttggg agattctttg ttaataccca ctcgtatcta 180 tgttaagcca cttttacatg tcatcagaaa aaatattgta aagggtatgg cacacattac 240 tggtggtggt cttgttgaga acgttccccg tatgcttcct agtcatctca atgccattat 300 agacgttgat acttgggaag ttccagaggt attcaaatgg ctgaaagatg ctggaaacgt 360 acctatttcg gatatggctc gtactttcaa tatgggtatc ggtatggtgg ttgctgtcgc 420 ttctgaagat gctgaagaaa ccatgaagga attaacgtcc gtcggtgaaa ccgtttaccg 480 cattggtcag cttgtggata aagaaagcag cagtgagcgt tgtcatttgg tgaacctgaa 540 caaatgggaa acattttgag ggaaattgtt taatctgtaa aacatatatc agtactttaa 600 gctaatttgg tcgtttttgg attttaagtt ctttttcatt taataaattg atggacttat 660 tgtatgtgta taaggttttt ccattcttta ctcagaacgt tgtgtatatt ctaacaaaaa 720 cttaagtaac tacattatta tatccaataa tatccactaa ataaatcgaa tgctgtaaaa 780 aaaaataata ttactgtact cgccttaaac atcaatatgt tttagtagag ataagtgcta 840 tgcagatata aggctaatac ttatataagc aatctgttca tattcaaata atgtgtagtt 900 agatagacaa ttgcaattga tcgtttcacc taactattaa ccagaaacgc cgagaccaat 960 aaataggaat gtgatagcta cgccgaggca tgcaactaca cgattgataa ttctccaatg 1020 aacatgttta accctcattt gatgtatttt ggtccgagga atgggaagaa aagaagctaa 1080 tatccacaac gggggaaata caattccaaa agtaaacaaa aacataaatt tcgatacacc 1140 atttccattc ttaaacttga tagaagcata tttctgtgga tcgataaaat tagaggaatt 1200 ttctttttct gaatttgcaa taaaggatgt cgttgctcga cgaatgtttg aattcgaatc 1260 ggtccgtaac atagtggtgt ctaatgactg tgcaggtatt ggcattcgac cgaatatccc 1320 ggaagaagaa gaacttaaac cagagttttg tgaacttaaa ttgctccctt gagaagttaa 1380 cgaagcatta tcttgtaaag ttgagagatt aggtttcgag tctaagtcaa aaaaggggac 1440 aaaggggttg ggtaactcgt ctgatcttgc aaaaaattcc ataggaggaa aatgctgaga 1500 atcgtctatg tgaggagaag tgaaatgact gtatcttgaa gacaagttgt gcaaaggctc 1560 ggatacactt ctttgagaag catttttctc tatgactata ttttgtagcg cactcggtaa 1620 tgaaggcttc cgaaaaaaag agagatctga gatttgtggt ctcgcaggta aaggcaaagg 1680 ttcagctggg atatgatcta agaatttgtt agcaaatgtt gaaccaaagg ggttattagg 1740 atctgaagaa ggggttcttt tgtgcatggc tgggctatgc ggtacacttt ttggcaagga 1800 taaaagggat aaaccagtgt cattagtgta atttgatgat agttggctct cagacccaaa 1860 atcgaatcga ttagtatttg aattggaggg caattgggga ttaaatgatg ttgagattgg 1920 gctactttga gttgttgcta aagtagctga cactgccctt ttgggagtat aagctagaaa 1980 cggaggagat ctctttgaga gaggttctgc agattctgca ttaccatcaa acaatatctc 2040 actagattgc tctgttaccg tactgtcggc acgatggaac tgtggacgat cggtttttac 2100 agaagagtgc cttataatag gttcattcga ccaaaatgaa acgttcgatg gatttttcct 2160 gctcagagga ggacgtttct tccttgaaga ctctcctttc tgtctaccgt cttcttcacc 2220 caaacggtaa gcgctttcat ctctgcgttg agcatgtcca ccgagatttt caaaagtcat 2280 gttttaacaa taataaacaa tattagaaaa acgcaaaata ttttcagttg tccaaataac 2340 tataggtaat aagtagatga tatgcttcta aagcgcatta gctccaacag aacatttcaa 2400 tgtagcaaaa tcttcaagtt ttaaaaaaga atgaaatcaa attatataaa agaaagttat 2460 ttttgtggat aaaagaatga aagatcaaat taaagaatga ttatgaataa aaaaaaagca 2520 aaagaacatt aattatgatt aaacaaaagg atcgactaaa tgcaaaaaaa agaaggacaa 2580 ggagtaggta aggatataaa agcgaatggc tttgctaaat aagcagaaga aaatagtgga 2640 acctattgtc ttatggtaaa agataaattg cggttgcaat gtggacccat attataaccg 2700 tcaaggttag catagtagta cgaacagtat attgctgtaa acaatggaac aaagaaagat 2760 accgaaaatc taccataaac taagctgcat taagaaaatt taaatcaaat ttacaaatac 2820 gaaattatca aattttaaaa tacgtagaaa tagcaggtgt aataattcga aaacaataga 2880 agtttgacat tgtaaattgt aaagcttata aataaaaatt taaacgaaca agaagaacca 2940 atgaaagatg taatcttaaa ataattttaa acatatcaca cttactgtac aaatttgagt 3000 ggaaacggaa ggcttgattc aagtcaatag caagcacatt tttatgtaag ggaaatcaaa 3060 agaaggcgaa acatggatat agttaggcat ctcataaatt ttagattatg ttttgttgat 3120 tgtaattgac aacaatgaat ccagcaaata ctagcaagga accaaggata agactaaaat 3180 ttaaataatg acccttaaga agtatgtcaa agaagagagc taatgggata ctaagactca 3240 tgcctactgt gaccaataag ggacttgtca ttagcatagc aataacccaa agataatctg 3300 aaacaaaggt tatcgaagca tttatgataa gcacaatcaa accagctgtg gtagagggaa 3360 gtgaaaagcg ttcaacgcca tacaaatgca aaataataag gaaaggccat aaaaggatga 3420 gatcaaaaag accaacaagg ccaaagaata ggcgtgttga aacgcaggac tcctcagtaa 3480 tatgaaattt aaccatcaca gagtagcaac catacaggag agctgccaac aaggcataag 3540 catttcccaa agcaggtcgc gatggggggc tatcattcaa atcagcttgc ttggcatctt 3600 gagtcactac tataataacc ccgccaacgc tcgccattaa agcgagtagt ttactcaagg 3660 taaatctttc aacattgaca atcgttccca aacctagtgt aaaaaaccca ctcatactgg 3720 agataatagt gaatgaagca acattggtaa atcctaatga gctattactg aagtaattag 3780 ccgcaaacca tatgatgcaa aatcccaaac taagataggc tgtttgtcga aatcctagag 3840 ggctgtttgg gcgcgtacca agattaaaac tgctatcgtg tacagattca tacatcgaca 3900 actcggacat tagcctgtgc tttctagttt ttttttcact gaaataccat ggaattaagt 3960 agaagacaaa tgtacccgtg ttgatataag tgattaagaa aggactaaaa aagttatcat 4020 cgtctaatag gctgcttgtg agaaaagaac tgatgagcca taaaaagacg acaaacaata 4080 aaagaacaac gcctagtgca tgtttcccaa tagcctgaag caccattttt ttctataaaa 4140 tttataaata atgatataat taataagaaa ggaaaacaag taagataaat tatggataga 4200 ctgtaaattg catttataaa gtgaactgga agaaactaaa aaaaatactt ctcatcaaat 4260 cattcacaaa aataaataat tataaaatta ggtccattta agaagctttt ctagtaaatc 4320 gagtaatctc accttaaagt agtaatggtg gtagggagga tgaatctata acaaacttat 4380 ataagctgta cgcaatttca gtttctctta cgttttcaaa ctatacgatg attaaagcgc 4440 caaattggga ttttttgctt tgtttatttt gttcaagcca aagaaccatt cttaattgct 4500 aaattccaag ttatggattt taattgacta aatacaacca catcttctga tgccactaac 4560 tttgaatatt cttttcaacc atatttctac aaatgttttt aatgttaaaa ggttgatata 4620 aatagaattc attttgctag atcaagctag tttcagataa ataatagagc atcaatgaaa 4680 gctaacggca taagcaaaaa taacataaaa ggcagacacg tcgtaccaga ggtgcacgga 4740 cttagttaat cattttgcga ataaaaggcc gatctaaata ctttaacggt ttctatgctc 4800 tcaacactta aatgaagagc aacataaatg ggaagaaaat ggaaataaga gaaaaggcaa 4860 agactatcat aagacaccaa tcatgcaaat aagaaaaaac ccatacaaag aaatgtcctt 4920 aattaagtag ctttaagaag aatagggttt aacagtaaca tgaagttttt tgactctcca 4980 tatctaaatg aataggatct gtaaagtctg ccgcaatatc gtcagaatcc atgttctcca 5040 gagctaactt agccactgtt tcgaatgctt cttgaacatt gatagcttct ttagcacttg 5100 tctcgaaata gggaatttct cctctagctt ggcaaaaggc caatgctttt gattttgaaa 5160 cctgaaatta ttagcaagaa attctcagct ttgtattaaa aattcaatac tttagacaca 5220 taccatcctc ttttgttctt ccacgtcgac cttgtttcca agcaagataa agggaaatgt 5280 ctctggattg ctcggtgatg cttgaatcaa aaattcgtcg cgccagctat ctaaagtttc 5340 aaaggacttg ctgttattaa catcataaac gaggacacag caatctgcgc ctcgataaaa 5400 cgcaaccccc aaactctgga accgctcttg accagcggta tcccagagct gtaatgtaac 5460 gactttgtca tcgaccagaa cttctttggt aagaaaatcc gctcctatgg ttgctttata 5520 atctttgcta aactttcgat tcacatacta aacagatttg gtcaataact ttcatttcaa 5580 acatgacagt cataacatta acatatttca aaaaacatac ctgattcatg atagaagtct 5640 ttccaacacc gctttctcct aaaataataa ctttcagcaa atgcttcttt ttgccggcca 5700 tatttacagc gtaaaaacga gataattcga tatattattg aaggccaata gtcctaattg 5760 aaccaagaat ccttttgaga tctgcaaaaa aaaataaatt tataaattac ttctttcttt 5820 gaaacggaaa tagttgcgca cgttcccttg gtgtttgctc tgcgagtatc aaggcttgtg 5880 agtctaccct tcatatgcct ttcacgtcat gagtataacg aacttcatca tgcttgggta 5940 ttttgatcaa aagaaatatg gtaaacttca ctatttaaat aattactaca taggcaatcc 6000 gatgtatact gacaactttc ttatatgctt gtcgaaaaca gtaatgattt attaatacat 6060 tggtaggaat ctaagttttt atttaaattt tattttttca agatttagta gtcaattttt 6120 ccagttcttt catctcgtct cgtattgagt aagttgctac catattttgt ttgtgttgtc 6180 ttcaagagaa tatcacgcag tctcctatct aactggtgtt aaatggagtt aattaaaaaa 6240 atacaagata gggatgctgc tgagaaagcg tattacgatg tcatagaacc atattcagaa 6300 cttttggaat tcagttttca caaagagttt gtgagtgaag agaaagtcac ccaaaggact 6360 gcgtcaagcg attctctgaa caccattgct agtgagaata atgacgagaa cgtaataaac 6420 ctagaagaat ttcggcaatt gaaaaggaat tgtgatttat atcaaaggaa tttgcaaaag 6480 ctgcagctgc tgttcaaaca gcaatcccaa aaaaacacac tcttagaaaa acagctttca 6540 ctacaaactg agttgaatca ggagaaagat aagcgggtta aaatactcca agatgagctg 6600 tgggctttac aacttgaggt agctgcttta gagaggaaat ctcctaatgc ctaaaattat 6660 ccgggattca attttttgtc gacagattat tttagttata ctgttaaatt tagaaaacgt 6720 cgattcgcgc taggttcact aattatgatt ttacgaaatg tttgttatgc ttatggatta 6780 atattaaata ttttctagat gatttcaagt taaaaaggat acttaaaagc ataatgagag 6840 gtcttcgctt gtactcgtcg ttccaatttt agaagttaca agcatagact atctcttcag 6900 tggttgaccg cacattttta tgtcaatgga tatgtccttt gtataatgag gaaacataag 6960 cattcaatta cttgtatgaa gatttttcgg cattaatatc ttcatgaata tcattttcta 7020 catggtcaaa atagtaaatt tgattatctc aattcaagta gcttatgttc ccctttttat 7080 ttccttatcg gtaacgccta cgagtaattg aattttcaat ctgtattatt atttaagcga 7140 tgtcttgtta taagtattgg ttgaaaaaat attatgcatt tctttaatac atttgatttt 7200 cgtcacttgt atgcttctaa tgagattggt tcatgaatga caacggttca acaaaagtat 7260 aatctagttc ttactgagta atcaaaacga agaattatcc ggcgaaacaa aatatgtctg 7320 cccaaagctt taagttgaat ttaataatag ttgcataatt ctttaaactt tagtatttag 7380 atagttcaga aatattgtat tgcttgcaag attgaatata aaagcttggg tatctaagcg 7440 taatgaatgt tactatttcc attactctga gcgacaatat ggataactca gtactagttc 7500 atagtctttt aaggtataca caaagaaaat tagaaggata ggaaatagaa taagaaatat 7560 aacttgtttt atacagggtt atactcaaag acaaatattt gatgcaaggg tttaatttta 7620 aagactacga tatacctaca atacactctt tttccctact gctatttggc attcaatcaa 7680 ataaagtgct gcttgttaga gcagtaagca aagaatacat ttatcattgg aaatttaagt 7740 acgattggta gtttattgat tcaaggtagc ctgctagaat ttgatattta atgttaatcg 7800 atcaattttg tcaatgagat tttgtgtggg caattgttca ctttagtttt cctaaatttc 7860 gtccagtgta tttttataaa gcatttattg taaaataatt tgaaaaatta tccactaaaa 7920 catcattctc atgtataatt ctataattga ttcacgctgt attcaacctc caaccatgta 7980 acttcaaatt tttcttgaac ttgttcagaa caaaccatcc gggaaatcac ttccattcaa 8040 atctttgcat atcataatat tttttcttac aaaagttaag ttgctagatt tatcactaag 8100 gggtcgtgtc tattgatgtt cactcattta taaatttgca aacgttattt atattctgtc 8160 gttgttaaag gacatacgaa tttccataat aattattaaa atttgtaaat ttatttgtga 8220 acttcagcat ggttgtagat actaaacttt acgacattct agaggttcat ttcgaagctt 8280 cagccgaaga gataaaaaaa tcttataaaa gactcgcact actacatcat ccggataaag 8340 caccaattca tgaaaaagaa gaagctgcag aacgattccg aggcgttcaa gaagcatatg 8400 atattttgaa agatcctgaa tctagagaaa tgtatgatat gtacggaatg aactcggatt 8460 caaatagtca atttgatggg ggtgtaaatt tggatgatgt tttagctcag atgtttggta 8520 tgaattttga agctggaggc cctggcaaaa acgttcctcg agaccggaaa cgtagaggtt 8580 ctgatgtaat tcacgactac gagatttctt tagaagatat gtttaagggg aaagaagtaa 8640 agcttcgtgc aactagaaac acactatgcc ctcgctgtca gggtcgtggt ggtaaacgat 8700 ttgctaaaga aaaaccatgc ttgtcttgcg atggtaaggg ggttaaacaa cacctaaaac 8760 acgtcggacc acatcatgtt acgaatagtc aagttatatg tgatacatgc aacggaaaag 8820 gagtttcctt tcgcggtaaa gatcgctgta aacattgcaa gggaagtgga acggttcctg 8880 aacagcgaat gctttcattt ttcgtaaatc gctcagctaa ggagaacgac aaaattattc 8940 agcgcggcat ggcagacgag gcatacggta taacacctgg tgatgttatc ttgcaattac 9000 accaaaaacc gcaccctgtt tttgaacggt taggtgatga tttaaaagca aaattaaaaa 9060 tttcattagc tgaagcactt acaggattca atcgtgttat tttgacgacc ctagatggaa 9120 gaggtcttga atatgttcaa ccaattggaa aaatattgca tcctggcgat tgcttaatta 9180 tacctggtga aggaatgtac aaggattcaa aaacagattt aagaggcgat ttgtatttgg 9240 aggttgacat agagtttccc aaagatggct tgataggtac tacagaaatc gaaattctgc 9300 gagatatcct tccttcaatc cctaaggttt ctgtgatgga tgatacctta atagattcgg 9360 ttagaggtgt acctggcgat atttctcatt ttggaggaga tgcacgctac gctaacgaag 9420 attatggaga tgaaacttat gagggagttc ctgaatgtca ggcccaatga tttctttttt 9480 ttatatataa taagaattgg cgtcttattt taattaagaa aaatttttag gttcaaaaaa 9540 gtcggaattt tgtctcaatg aaacaaataa aactacttct cgtacaacca ttgcaaaatg 9600 ttatgtccct aataaagcat ctatactaca gaagcaaagg tatctgtttg tatgtataaa 9660 ccgattgaga atggaaaaga tcaatataga taggaatcca ctaataaact gatctgcaaa 9720 atcaacatta taaagccttt aaatttgaca gccaagagtt tcttatgcaa tgaactgaca 9780 tttaaaggaa aaaagttaat tatatgaacg gaaaaatatt ttatgggaaa ggacatttgc 9840 aagttatcat tgtcgttgca ttcccaaacg ttaaagtcgt tattgccaaa tgtaacataa 9900 atatgaatgc acattattaa gaacgaagca ttgtaaaaaa ccaaaaatca tcagaagcaa 9960 aataaaattg gcaagcatca gaggttttgg agcattgaaa tgggataaat attaattcat 10020 acgtgagttt ttacagcata ataggaaccg gttgttttat cttctgtgct atgattcttg 10080 caaattcttc aaattgtaaa aaaaaaacat ttgtgttttg aaaagtggcg attttttgtc 10140 cgtataaagc aatagaaaaa gcaagctttt gaaaagaaat atgaaggttt tgaatcatac 10200 ttaaccaatt acctttttct ttaaaaaaaa ctaggaaaac tgtaagtcca aagtaaataa 10260 ctttagctgt aaataattaa tatttttctt ctaaagaacc aaacaacccg tcaatttgtt 10320 atagcaataa taaacagata ataatacttt gttaaaaatg tggcttcgat tgcaaaggat 10380 aaaaggctta aatgagaaaa taacatttaa ccttttgttt taatacggcc gagtgtttta 10440 gtgatttcat tcattcatac ataaaaattg taaacaaacc cagtaatata aacattagtt 10500 caactcaact tgagcattca gttattttaa gaaggaatgt aaaatctaca tatagctgct 10560 catgaaaaag atttgttttt ataaatttag ttatttaaaa ttaaatggaa ccattggatt 10620 ccccaagttt ttggccttca aaattcatgt tgaaaatata tacagaaaac aacaaaatac 10680 ggtttaaacg tgaactcaaa caatttaaat gttacttact ggatttcaaa acataatttc 10740 tacataaatt ttattttttt cattagggct aaatgattac aaaaagactt catatgaaaa 10800 ctgtagccct gggatgaaaa ctatattcaa tattcaaaac aaacattgag tttttgcctg 10860 cttaggcaaa ggcacaaata tttcaaaaga tagggtaggg ttggttgaaa acagtcacgc 10920 catgctacca aaagtttttt ccagacggta ggtacagtgt agactttaca cgatggcacc 10980 tggactggtt gttggtttaa acaagggaaa gactttgact aagcgtcaac ttcctgagcg 11040 tccttctcgc cgcaagggac atttgtccaa gcgtactgct ttcgtccgat ctattgtgcg 11100 tgaagttgct ggatttgctc cttatgaacg ccgtgtcatg gaattgatcc gtaactccca 11160 agacaagcgt gctcgcaagc ttgccaagaa gagagtaagt aaccttttga gtgcatttaa 11220 tttaattttt ttttttttaa ttttgtgaat gaatactaac aggttttagc tcggtacttt 11280 gaagcgtgcc aagggtaaaa tcgaagagct cactagtgtc atccagagct ccagattggc 11340 ccattaaact tgtcttccat ataataaaat tactttagca aatatcaact tgttatgatg 11400 cgtagttgtg tacgagaggt aaatggtaac tctcaatagt tatcaaaaag aataattatc 11460 gtgcttttat tggcttaagg catattctta caaaggattt gagaattggt acaatcacac 11520 cagttttttt tttttttttg cttttcatat taactaaatg ggagtgtaga agaacctaca 11580 atactagaag gtttaccgat tttggagaat acataaaatg catgaatgac tgttgcaaac 11640 ttttgtttgt gtaaagactg agtgaatgtc tttgcaatta gatttggcga taggaggtta 11700 ctatttacca tgtagtaaat tatacttgta aacttagatt acgtgcattt aagaataatt 11760 taaaaaaata aacgaaatac aaggaactcc cgcaaattcc tgtaatgcta tgattccttt 11820 tttaaaacgt aatttaacaa aatatgcggt tttaaacata ctgtttactt ttgactcaat 11880 aggtgactta tgagttgcga cgggaagaag tgccaaaacc cctaagatca acagaggaat 11940 taccgatggg caaagtgaat tttaagagaa agttaaaagt gcaaatgatt aatgctttcc 12000 tattccgaag aaagtatttc cttatagttc ctttttccac ttgaattatt aagacctcaa 12060 agttgagatt tatttacctt tgtaaaaagc tctttcaaca atgtcttatt gtttattaat 12120 tcattactca ttcaaatcag aacgccttac aaagtcctac atatctttac cgatatgtta 12180 caaattcgtt attaaagttt acaggaacgg aacgatttct ttacaaaact gattcagtga 12240 ctctgtctct cccgttatac tagccttacg attcaagtcc atttcattat ccaatgttgc 12300 cagcgaccat ggatccatta atggctgatt ttaagatgag ttcatggaca gcttcgggtt 12360 ggccacaatt aggcaaccag taaatcacct tacttgtctt cctccatgta actcgtagat 12420 cttacacatt ggagtagcac gctacttgaa ttgttatgaa tgatcaagtt gctagaaaaa 12480 acaggaaatc gtttttgtag acaagtcgat gacaatggaa aagaaaacag agttgggaaa 12540 gaaataaagg aagtaaacaa aaaagcgata tactggtttt cgcatttcca gcatatattg 12600 gagccgatca cattatccca tacatagcta aatacagata atcaagatat ggagtggata 12660 taaactgatt gcttttactt tcagctgatg ttttgaattc ttttcatgtt acttttgatt 12720 actacttgaa ttcaagtgga agtggttttc aaaaaaagtt gcatctgcgc tatacactta 12780 ctttagtaca tacactaacc acttgctgct ctttaggaaa agaccgtggc caccacacat 12840 tcactaagtg ggggataaaa gctgcaaccg tctatagtta aaggaaggga caacgaccgc 12900 cacataacta cctgatgggg gcaactaaca aagacgggtt ttcttccttc attgccatcc 12960 catctcgctt gttatctaac cttgtttcat aatttcttgc agccaatcat tgtcatggcg 13020 agaaccctta agacgcaaca ccaaccaacc agctttgacg tcacttgata tcgctaaccc 13080 gtttgcgaca tttaacgaga gcactgatgg caaccttcgt tagaagggaa actacagtca 13140 aatggtaatg cgaagaaagg gatttccagt atttttcttt catggaaaaa agagtgttga 13200 tatatttgga tgatcggtta atttcatact acgctttttc cttctttgcg ccgtttctgc 13260 cacttctact caagctcttc acctgttttc cctcttgtta gctcaatgcc cttcgacatt 13320 ttttcaaatg tctcttactg ccttgctgcg ttgctctgtt cagtgtagtc gttatcgctc 13380 gagttcagta cgctcaaaac tgaacccatt gtgttttcat aatttgcctc gctttttcgc 13440 tctatcaaat tacctataat gcgaaaatta ctgtctacgt aatatctacg gtttcgctat 13500 tggatttcgg atggcggcgg ccaaagtagt gagcgttgcc ttatttcatt atgggattca 13560 tcatccttaa gtattagtgt gtgtgatcca ttagcgtcca tcccactact gttaagcaaa 13620 catcgttaca tcgtgtaact aatcttgctt tcggaacttg attcaactca cattctcatc 13680 tttcatacat acgtatcttt tccaccttgc gcattttcgg ttaggctggc aaattccccc 13740 aatcataaaa aaatcggcga cgctcttagt ttgctcgatt cttggaaaat cctcaacagg 13800 cgcctgaatt tttaagtcgc tatacgttaa acttgagccc cttttttatt tccttgctac 13860 cgtcattctc gtcgtctcgg aaaaacagct taaaccttgt tgctggtaaa gcaggtttgt 13920 aaagattttt cctcttgttt tcatttcttc ttttgtctta tcgcccttgg ttcgttgcct 13980 ctacaacacc tacctaacac ttgcgaccac ctcattttac tcttttttaa gcacctgtct 14040 catcaattga cagtgccaat tggttgaaaa tcgctacaac cgtcattcga ttccgttcca 14100 ttcttgtaca taaagataat ccaaaacttg gtggatgttg gctttagcgc tattgtaaaa 14160 aaaaaattgc tttaaaagtc aatcaagttt tccttcgttg tttgttttag taaatttttg 14220 tcttcttctt cttcttcttt ttggcctggt tgggtttggc ttggtaaatt cattatttct 14280 tcaagtttca ttgacaccgt ttcattttgt catatacgat aattaacgaa agctctccat 14340 acactccatt caacgagcat tgtattttac tccatcatct gttaccgcat ttgcttgctt 14400 ctcttcactg catatcaatt ggatc 14425 //