ID SPBC3E7 standard; DNA; FUN; 34642 BP. XX AC AL023534; XX SV AL023534.1 XX DT 11-MAY-1998 (Rel. 55, Created) DT 16-FEB-2000 (Rel. 62, Last updated, Version 4) XX DE S.pombe chromosome II cosmid c3E7. XX KW 2-isopropylmalate synthase; DNA J; dna repair protein; KW hsp16, heat shock protein 16; major facilitator family transporter; KW methionine aminopeptidase 1; phosphatidylinositol-4-phosphate 5-kinase; KW rad13; RNA-binding; small nuclear ribonucleoprotein F. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-34642 RA Lyne M., Wood V., Rajandream M.A., Barrell B.G., Brown D., Churcher C.M.; RT ; RL Submitted (06-MAY-1998) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk. XX DR GOA; O14368; O14368. DR GOA; O59722; O59722. DR GOA; O59726; O59726. DR GOA; O59730; O59730. DR GOA; O59732; O59732. DR GOA; O59734; O59734. DR GOA; O59735; O59735. DR GOA; O59736; O59736. DR GOA; P28706; P28706. DR SPTREMBL; O59722; O59722. DR SPTREMBL; O59725; O59725. DR SPTREMBL; O59726; O59726. DR SPTREMBL; O59727; O59727. DR SPTREMBL; O59729; O59729. DR SPTREMBL; O59731; O59731. DR SPTREMBL; O59732; O59732. DR SPTREMBL; O59733; O59733. DR SWISS-PROT; O14368; HS16_SCHPO. DR SWISS-PROT; O59730; AMP1_SCHPO. DR SWISS-PROT; O59734; RUXF_SCHPO. DR SWISS-PROT; O59735; YHXF_SCHPO. DR SWISS-PROT; O59736; LEU1_SCHPO. DR SWISS-PROT; P28706; RA13_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c3E7 is overlapped at the 5' end by c6B1 and by c4F6 CC at the 3' end. XX FH Key Location/Qualifiers FH FT source 1..34642 FT /chromosome="II" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c3E7" FT /map="IIR" FT misc_feature complement(1..57) FT /note="nominal overlap with cosmid SPBC6B1, EM:AL021838 FT S.pombe chromosome 2" FT CDS complement(1..4010) FT /db_xref="GOA:O59722" FT /db_xref="SPTREMBL:O59722" FT /label=SPBC3E7.01 FT /note="SPBC3E7.01c, probable FT phosphatidylinositol-4-phosphate 5-kinase (partial), FT len:1336aa, similar eg. to YFR019W,FAB1_YEAST, P34756, FT probable phosphatidylinositol-4-phosp,(2278aa), fasta FT scores, opt:587, E():0, (25.8% identity in1443 aa overlap), FT contains PS00030 Eukaryotic putative RNA-binding region FT RNP-1 signature" FT /partial FT /gene="SPBC3E7.01" FT /gene="SPBC6B1.11c" FT /product="fyve finger containing putative FT phosphatidylinositol-4-phosphate 5-kinase" FT /protein_id="CAA19005.1" FT /translation="MSEVETPTAASPTFPVETSHRLDTLHTSSTEQIIKDSENVVHTTL FT KLPTSTLSREFWMKDERTNNCSLCETEFTLFRRKHHCRICGKIICKYCLKEAPGFIFRL FT QGSIKVCRPCASILVNNYSRSQLFNHSLNESKNRDLTEQHPFVTLDELNSNDQVLSSFG FT DLSSTFEMPNNIHPPEVAPMIAIPSSRSNYDSPGWAHHSIFLDWSKRNLDSNVINVEDS FT ESGKYNALTITNSYDAGPSSVSTDYRPVNFGKVPSYSKLRKNKAFSSAKVSDMYLSADE FT RNRLEDFSKGDRGLSFVNLSPNIKATSYDRLSTVINEPFISRSSSLTDERGLADSGNSY FT HHFSDSDDESLFNDGLGLSFHANSAIIKQRQQNVASIQRYGNESYLSNFLKAFLPKTVC FT DYLFPSSTIPDGLPALIENFNARVDKVNHPGGTEEPLPYQGKSRASSVVTSSKSTCILP FT PWILFSDSFNQLVCTFLGKLLFQMLNDEGVDSPMQWVLCLPKILLKMALDLGPDIRSGD FT DIDVRSYVKIKKIPGGSIQDCFLVNGVLFSKKASSKSMDRSLRRPRIALLTFSLDYACD FT EQRILSLDLIISQQEEYIINLVNRICMLKPNLVFAQGQIPSIALKYFEEHGVIAFHGLK FT ESVLYDIARCCRADIISSIDKLSLCPRLGTCGRFQLRTYVVDENKGLRKTFAILDRCSE FT RLGCTIVLRGADYNQLSKVKKIVELVVLIAYHIKLECALLRDKFVNMPELFETTYQSLS FT RKSLPSFASTAADKEKSQNHEKKSLNSDNQSLRPLENENQSVSSTQGSNSPLELINNLP FT ASDDYSSITKALKTRFLTFSPFLSKPLPRLLNQVNYYQFIRNKLLKDVKLHPYSPTGSF FT VMKQSENDNVEESYEESYKFFCIDERYHFLEKQWTLYYSHSKLMFSPFSSQRIILLYSI FT INKETSVPCIGPERCLLEFYRETDCTLGQYIEDSCLNTNVSCGGEYCKTNDMLWHYRSY FT VHGNSRISVFLESFSCPVPGLEEKIIMWSYCKFCKKNTHITVMSEETWKYSFGKYLEFM FT FYNSQIRDRFEFCDHSVMAQHVHYFGYCNMALRFQRDLIEIFELFVPSVTLRNNPSYIK FT ELKEKEYKRLKGVIEKCLSSVASRINQIKCDWVTDPEKFESCTSEISKFRTLLSSDYTE FT LYSEFDSIYLNSSTSDYLSLNSILRVLQGKMVKWEQRFLDYQRLYLPSYKELSKIAAAQ FT IKKVFLERPLSQTPLDLPETLENTQIDIYPSFKTESTDDQLEKVTQTNVASNKRVAPYA FT DSMANVGSPESDCFSVATSSDIPKANIDFTNDISTQNTFPASPVSNSGFSRQT" FT misc_feature complement(3111..3134) FT /note="PS00030 Eukaryotic putative RNA-binding region RNP-1 FT signature" FT misc_feature complement(3669..3842) FT /note="Match to PF01363 FYVE, FYVE zinc finger Score 79.02" FT CDS complement(5157..5588) FT /db_xref="GOA:O14368" FT /db_xref="SWISS-PROT:O14368" FT /label=hsp16 FT /note="SPBC3E7.02c, len:143" FT /gene="hsp16" FT /product="heat shock protein 16" FT /gene="SPBC3E7.02c" FT /protein_id="CAA19006.1" FT /translation="MSLQPFFGFPPTVNDLFSDFVSYSPRLNNQIPGELSPSIDVHEGK FT DTVSVDVELPGVKKEDVQVHYDSGKLTISGEVVNERKNESTEGNQRWSERRFGSFSRTI FT TIPAKIDADRIEANFSNGLLTVTLPKVEKSQTKKQIAIK" FT misc_feature complement(5160..5489) FT /note="Match to PF00011 HSP20, Hsp20/alpha crystallin FT family Score 85.67" FT misc_feature complement(5160..5492) FT /note="Pfam match to entry HSP20 PF00011, Heat shock FT hsp20proteins" FT CDS join(complement(9143..9319),complement(8703..8903), FT complement(8495..8608),complement(8305..8358), FT complement(7505..8242),complement(7364..7426), FT complement(7155..7317)) FT /note="SPBC3E7.04c, len:158, SIMILARITY:Drosophila FT melanogaster, CNN_DROME, centrosomin, (1033 aa), fasta FT scores: opt: 104, E():3.4, (33.0% identity in 109 aa)" FT /pseudo FT /gene="SPBC3E7.04c" FT /product="psuedo; gag acceptor, and out of frame" FT misc_feature complement(7318..7337) FT /note="ctgattaaaaaaaactaaag, splice branch and acceptor" FT misc_feature complement(7358..7363) FT /note="gtatga, splice donor sequence" FT misc_feature complement(7427..7439) FT /note="ctgacgttggtag, splice branch and acceptor" FT misc_feature complement(7499..7504) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(8243..8258) FT /note="ctaattcttccttcag, splice branch and acceptor" FT misc_feature complement(8299..8304) FT /note="gtacgt, splice donor sequence" FT misc_feature complement(8904..8915) FT /note="ctaacagattag, splice branch and acceptor" FT misc_feature complement(9137..9142) FT /note="gtaagt, splice donor sequence" FT CDS join(complement(12000..12062),complement(10428..11960), FT complement(10333..10389)) FT /db_xref="SPTREMBL:O59725" FT /note="SPBC3E7.05c, len:550, SIMILARITY:Caenorhabditis FT elegans., Q22505, similar to l96 protein., (727 aa), fasta FT scores: opt: 215, E():2.8e-05, (22.8% identity in 561 aa)" FT /gene="SPBC3E7.05c" FT /product="hypothetical protein; possible coiled-coil" FT /protein_id="CAA19009.1" FT /translation="MNRQLRTVKSCFSLQKTHQYRSFWIQSSLRALPPDVKQNKTEPIP FT FVPKPEEGSSNKSNSSKFRKRFLLLFLLGITGYSCSVVYCFKDPNFYDYFAEHTPFGKQ FT VLYNVEQSWIGYKYLGGNRIKVDDSSPKLKQNSNNISKKQNSSRNDDTKVKKDTTIERP FT ESLVVEIVDLPSEVTKDTAEESVWKDIGLDQETGLSVTAIPIITETLDHAHEQEIKDQS FT LRFESSLNEANELHGKLSKIQQEQEHLFEQRLREKVSEMESKLEALLIARDEKWQSAFE FT SEKLRLQKLHEARLQQELFKLASVFESKLKNELTEQAITLEKLHLQSIKAQVEQERGSR FT LGRLQELRNSFQQLQELVRVVLHENGRVTRLVDVSNTLDDLNKDMRFHKLSEVRQHVNT FT LKEATKDDELAALASRVIEKIVDSGPILDKEELQTKFDTLSKEIYKTCFLTTESGFFGH FT LKSIILSQLPAAVFKSPDIVSVKKTLEDARSHLLKDDLDGSVRALLSLSQWPRALSRDW FT INACRRRMELQQAIEIIKASATLSSQLEDAQQA" FT misc_feature complement(10390..10401) FT /note="ctaaccaattag, splice branch and acceptor" FT misc_feature complement(10422..10427) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(11961..11971) FT /note="ttaacagaaag, splice branch and acceptor" FT misc_feature complement(11994..11999) FT /note="gtatgt, splice donor sequence" FT CDS complement(12874..14607) FT /db_xref="GOA:O59726" FT /db_xref="SPTREMBL:O59726" FT /note="SPBC3E7.06c, len:577, SIMILARITY:Schizosaccharomyces FT pombe, CAA20760, msf transporter., (531 aa), fasta scores: FT opt: 1192, E():0, (38.6% identity in 495 aa)" FT /gene="SPBC3E7.06c" FT /product="MFS transporter of unknown specificity" FT /protein_id="CAA19010.1" FT /translation="MSNPRTKSPNTNRGQGLRSERSALLNDSLSSLNGNSSYDSIKDSS FT KNNKDVAEVNEYPRRPESSVSVVSNSPHRQDAATTNTVSTVSVSKVLPALLLGVVLAAL FT DNTIVASTYTKIGAEFGKFSQVSWTATAYMISCTAFQPLFGKFCDIYGRKKTLLAAYCV FT FGIGCFLCGTSRSLWQLVAARAIAGIGGGGMNSTVSILMSDIVPLKQRGTYQGIINVFF FT AIGSSLGGPVGGYFADQYTWRIGFLIQVPLIAIAFLCVYFTLNLPHHNHVSFMTRFRKI FT DLKGLILLIIGVTTMTCAFTLGGNVREWNDPVVISLLIASSISYLSFVYVEAFVAFEPL FT APMDVLTERTCLSSYLCNFFHSVANFGWIYGMPLFFQSIKNEGAEKSGIRLIPMIIGSS FT LGSLLGGAVISLTGNYKKITVGSYFFGSVAALFMLRYGYSNFNWEYAVYPFSGGLGNGI FT AVTTTLVAIIHASPSAFQASAIATSYLFRSNGCVLGVSISSSIVQTVLGIKLRKSLDFD FT VDELLHHLRKDISYVHRLPEEIRQTVLDALLGSIHYSFLFVSFMFFCAFVCSMFIKNRN FT L" FT misc_feature complement(13042..14340) FT /note="Pfam match to entry sugar_tr PF00083, Sugar (and FT other) transporters" FT CDS join(complement(17364..17411),complement(17307..17318), FT complement(17218..17245),complement(17120..17174), FT complement(16841..17064),complement(16626..16702)) FT /db_xref="SPTREMBL:O59727" FT /note="SPBC3E7.07c, unknown, len:108aa, similar eg. to S. FT cerevisiae, YPL225W, Q08971, ORF, (146aa), fasta scores, FT opt:364, E():1.5e-31, (52.4% identity in 103 aa overlap)" FT /note="SPBC3E7.07c, len:147, SIMILARITY:Saccharomyces FT cerevisiae, Q08971, chromosome xvi reading frame orf FT ypl225w., (146 aa), fasta scores: opt: 518, E():1.9e-28, FT (53.9% identity in 141 aa)" FT /gene="SPBC3E7.07c" FT /product="hypothetical protein" FT /protein_id="CAA19020.1" FT /translation="MLSTKIDAENAENAAEIEMQFAVKAVEQAQIYWSLLEMRKGSELK FT LTKYDDEIFEDLINTFPEFKDPKTASFVNEDEMKSAKGKAAWRPFLMRYEKKVDDYNFG FT TLLRIKNTDEYEQETTIFVPRMQFLAYEIARNRYGLNDWIKKD" FT misc_feature complement(16703..16716) FT /note="ctaacaagtcttag, splice branch and acceptor" FT misc_feature complement(16835..16840) FT /note="gtatgt, splice donor sequence" FT misc_feature complement(17065..17099) FT /note=" ttaatttaaagttcaaattgcttactattgaatag, splice branch FT and acceptor" FT misc_feature complement(17114..17119) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(17175..17186) FT /note="ataacaatttag, splice branch and acceptor (atypical FT branch but intron confirmed by homology)" FT misc_feature complement(17212..17217) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(17246..17264) FT /note="ctgatttaaaaaattttag, splice branch and acceptor" FT misc_feature complement(17301..17306) FT /note="gtacgt, splice donor sequence" FT misc_feature complement(17319..17332) FT /note="cttacagattttag, splice branch and acceptor (atypical FT branch)" FT misc_feature complement(17358..17363) FT /note="gtaagc, splice donor sequence" FT CDS complement(17686..21024) FT /db_xref="GOA:P28706" FT /db_xref="SWISS-PROT:P28706" FT /note="SPBC3E7.08c, len:1112" FT /gene="rad13" FT /product="dna repair protein rad13" FT /gene="SPBC3E7.08c" FT /protein_id="CAA19011.1" FT /translation="MGVSGLWDILEPVKRPVKLETLVNKRLAIDASIWIYQFLKAVRDK FT EGNQLKSSHVVGFFRRICKLLFFGIKPVFVFDGGAPSLKRQTIQKRQARRLDREENATV FT TANKLLALQMRHQAMLLEENNKKATALANASVQNERQMPSSMTLDNSEIKPVLNQRKNY FT LKPDPYQLPEMDVSFDKLGSSYDPRIMSQDELTQYVSSFTKIEDINLFDFSNIDFDSEL FT FQSLPDTDKYSILSAARLRSRLRMGLSSEQLSEMFPNRMDFSRFQIERLKERNDLTQRL FT MDFTGMNEFGPSRVVSEKNREYILVKNEGAEGGWALGVISGSTNNEPIIIDDEATKLSS FT NLIDEDEDEAFYDVPLPSRSHSMNPRELVAAKLKEIKENSFSENQQSDEADYNVTDDLI FT LQLATQQSLEENKKSKELFSLSASEFDKLNSEKKTFEILSTDIPAEDSMNSLLNDEENL FT KLEHVGDVSNDSLAFAEKKHPENGTSIFMDALPSASREKKTNDLIDPLPFQPMDWGKSI FT FFEKLKKPTETFMDSKTDIPSEAPDNSKLVEDTNLHTINATVNIESDLDAAKPGIENPI FT ISPLLPVKDDEKDLDLRELNPLEPFENMKEQADDGTVTNPLNVSSDKAMSVYLLSSENA FT KDTGDIKSESIDAVLPTLETSSPSLSIPTDFQKEASPNKGAAALSSKVEPEVVEKLLDE FT EEEEMIIRMAEEEKEYDRFVSELNQRHETEEWNQEAFEKRLKELKNQKRSEKRDADEVT FT QVMIKECQELLRLFGLPYIVAPQEAEAQCSKLLELKLVDGIVTDDSDVFLFGGTRVYRN FT MFNQNKFVELYLMDDMKREFNVNQMDLIKLAHLLGSDYTMGLSRVGPVLALEILHEFPG FT DTGLFEFKKWFQRLSTGHASKNDVNTPVKKRINKLVGKIILPSEFPNPLVDEAYLHPAV FT DDSKQSFQWGIPDLDELRQFLMATVGWSKQRTNEVLLPVIQDMHKKQFVGTQSNLTQFF FT EGGNTNVYAPRVAYHFKSKRLENALSSFKNQISNQSPMSEEIQADADAFGESKGSDELQ FT SRILRRKKMMASKNSSDSDSDSEDNFLASLTPKTNSSSISIENLPRKTKLSTSLLKKPS FT KRRRK" FT misc_feature complement(18466..18732) FT /note="Match to PF00867 XPG_I, XPG I-region Score 175.54" FT misc_feature complement(18679..18723) FT /note="PS00842 XPG protein signature 2" FT misc_feature complement(20731..21024) FT /note="Match to PF00752 XPG_N, XPG N-terminal domain Score FT 206.01" FT misc_feature complement(20773..20817) FT /note="PS00841 XPG protein signature 1" FT CDS 21284..23263 FT /db_xref="SPTREMBL:O59729" FT /note="SPBC3E7.09, len:659, SIMILARITY:Saccharomyces FT cerevisiae, Q12232, orf yor154w., (587 aa), fasta scores: FT opt: 684, E():0, (36.8% identity in 405 aa)" FT /gene="SPBC3E7.09" FT /product="hypothetical protein" FT /protein_id="CAA19012.1" FT /translation="MVKRRLSAFGNAFLIYFIIFRLCCCSPQTSHWCKYPALCLKSPDT FT HNENLVCDAYLSVIATKSEEKEASNPTTWDFTPTNKYQEPSFHTKTSLNGSDTISSNFL FT SKYEYSNGTSTSEFIDSISPPLVNETSTISSSKKLEQNYSVTEVIDTNIITSSSVTLPI FT SEDGSSTSAAATIDSNIDEKTVAFSEEKRFNFASTDCAAAVIKTNPEAVGSSSILTENK FT DKYMLNKCSAENKFVVIELCEDIYVDTVQIANFEFFSSIFRDFKVSVSGKYPKYESSWM FT ELGTFTALNLRTLQSFHIENPLIWAKYLKIEFLTHYGSEFYCPVSLLRVYGKTMIEEFE FT EANEDFLEQKVNDGSAIKADEIRKPQESPIFVDEEDTDVQSKPVRKNPSVELNSTDTLL FT SSTVISKSLSTVVIGNETGKSESYPATSTRSFNDISPSSSSSYSTAQISTFPSNQESIY FT KNINKRLSTLEERKKAFDEIVEKILTNYGKHNAKNMNFTQLLHELNSTLQLEISKLSKS FT VVKPSLFALQAKLELLSAENEYFQSQITSLYQESSFQKRLLMLQLTVLIVLTVYMAVSR FT LPENLPTTRSSSNNPIEASRPPFSRDEQDISKANDFRVSASSAVYTVGPELLQRKKRDP FT NTSIRSIHEREQDKIIHSRSHSVC" FT CDS join(23540..23656,23709..23729,23779..23824,23885..24840) FT /db_xref="GOA:O59730" FT /db_xref="SWISS-PROT:O59730" FT /note="SPBC3E7.10, len:379, SIMILARITY:Saccharomyces FT cerevisiae, AMP1_YEAST, methionine aminopeptidase 1 FT precursor, (387 aa), fasta scores: opt: 1419, E():0, (53.8% FT identity in 377 aa)" FT /gene="SPBC3E7.10" FT /product="putative methionine aminopeptidase" FT /protein_id="CAA19013.1" FT /translation="MATEIAKHICCGIDCNNEADRLQCPKCLNDGVKSYFCGQECFRNS FT WNIHKHLHRPPNVEKREDGTYNPFPKFHFAGSLKPVYPLSPIRKVPPHIKRPDYAKTGV FT SRSEQIEGRSFKLKRLTPKEQEGMRKVCRLGREVLDAAAAAVRPGTTTDELDSIVHNAC FT IERDCFPSTLNYYAFPKSVCTSVNEIICHGIPDQRPLEDGDIVNIDVSLYHNGFHGDLN FT ETYYVGDKAKANPDLVCLVENTRIALDKAIAAVKPGVLFQEFGNIIEKHTNSITEKQIS FT VVRTYCGHGINQLFHCSPSIPHYSHNKAPGIARPGMTFTIEPMLTLGPARDITWPDDWT FT SSTASGRCSAQFEHTLLVTETGCEVLTARLPNSPGGPLK" FT misc_feature 23657..23662 FT /note="gtaatt, splice donor sequence" FT misc_feature 23690..23708 FT /note="ctaattcaaaaaaaaaaag, splice branch and acceptor" FT misc_feature 23730..23735 FT /note="gtaata, splice donor sequence" FT misc_feature 23760..23778 FT /note="ttaacactaggtaatccag, splice branch and acceptor" FT misc_feature 23825..23830 FT /note="gtacgt, splice donor sequence" FT misc_feature 23869..23884 FT /note="ctaatttgttcatcag, splice branch and acceptor" FT misc_feature 24061..24792 FT /note="Match to PF00557 Peptidase_M24, metallopeptidase FT family M24 Score 219.31" FT CDS join(complement(26248..26336),complement(26134..26206), FT complement(25100..26005)) FT /db_xref="SPTREMBL:O59731" FT /note="SPBC3E7.11c, len:355, SIMILARITY:Schizosaccharomyces FT pombe, YAY1_SCHPO, hypothetical 44.8 kd protein c4h3.01 in FT chromosome i., (392 aa), fasta scores: opt: 503, FT E():4.9e-23, (40.2% identity in 378 aa)" FT /gene="SPBC3E7.11c" FT /product="DNA J domain protein" FT /protein_id="CAA19014.1" FT /translation="MVQRVVDRDYYDILNISVDADGDTIKKSYRRLAILYHPDKNRENP FT EAAREKFQKLAEAYQVLSDPKLREKYDKLGKVGAVPDAGFEDAFEFFKNLFGGDSFRDY FT VGELNLLKELCKMINEEPELKAIEDTEESKKQLQREESKEADRLLQERIDVLCKNLLDK FT LSIWTETDMSDRVTDAFKQKMQFEAELLKDESFGNEMLHAIGSTYVQRANILIQSQSFL FT GIRGVWGSLCAKGTLLKDTWNTVVSAVDVQSSAAALAKAEEGEEQWSKEKRDEAARELT FT GKVLSATWKGTRFEVQSVIRTVSDKILYDKAVPLEKRINRANALLMIGQVFLKVAPNEK FT SDANYFEDLMNDRGK" FT misc_feature join(complement(26248..26312),complement(26134..26206), FT complement(25943..26005)) FT /note="Match to PF00226 DnaJ, DnaJ domain Score 59.56" FT misc_feature complement(26006..26024) FT /note="ctgaaataacaaagtatag, splice branch and acceptor FT (deviates from consensus but confirmed by homology)" FT misc_feature complement(26112..26312) FT /note="Pfam match to entry DnaJ PF00226, DnaJ, FT prokaryoticheat shock protein" FT misc_feature complement(26128..26133) FT /note="gtaaga, splice donor sequence" FT misc_feature complement(26207..26219) FT /note="ctaataaacttag, splice branch and acceptor" FT misc_feature complement(26242..26247) FT /note="gtaagc, splice donor sequence" FT CDS complement(27057..28427) FT /db_xref="GOA:O59732" FT /db_xref="SPTREMBL:O59732" FT /note="SPBC3E7.12c, len:456, SIMILARITY:Saccharomyces FT cerevisiae, SKT5_YEAST, skt5 protein., (696 aa), fasta FT scores: opt: 261, E():9.7e-09, (26.0% identity in 312 aa)" FT /gene="SPBC3E7.12c" FT /product="very putative chitin synthase regulatory factor" FT /protein_id="CAA19015.1" FT /translation="MPASTSIPETPSKLPDALLVNSDPASKVDNVSVKIEQESPLALEG FT SPLPTVSDVLPETNNAHEEVSSSSWSLSSSDSIMSYDSLSDDVSVLSFLDCPLTTFETA FT PSIASFSNSAADVSSHSRSSSSWSAKLSRFTKHASKPSLSSNSSDSSFSKSGSESNALS FT SRGSFELEPHGIHRHVSRAKRLLSKFYSKFHHKKEDSSFDPLAPLVFAPNTSRVLRVTN FT EANASAISLEKATSLSSQEQPGSEIKKELSLYDHEFDQILDLAIKAKKDGNLENAIEFL FT EYIMPEVASQQNFVPYELAELYKQRGTSQDLKSILPLYMLAASLGHDRSSFLVGEAFFY FT GTYGARENKLRALQYYHLANDKGNADAMLALCKLYLRGLPGHIFPSSRRAFEYAHRAAM FT LGHAPACYVLGKFYETGVGCVKDLAKSEAGFRAGLINDSPITDADALQIASTLVLLQ" FT misc_feature complement(27462..27509) FT /note="PS00589 PTS HPR component serine phosphorylation FT site signature" FT CDS join(complement(29352..29417),complement(28679..29302)) FT /db_xref="SPTREMBL:O59733" FT /note="SPBC3E7.13c, len:229, SIMILARITY:Homo sapiens, FT O95926, dj465n24.1, (243 aa), fasta scores: opt: 450, FT E():2.7e-18, (32.4% identity in 225 aa)" FT /gene="SPBC3E7.13c" FT /product="hypothetical protein" FT /protein_id="CAA19016.1" FT /translation="MDSPSHSREARVEKLKKIREQMRKSSHENRKEVVQEHSRMRIDPA FT LERRLERKRMEAEEELAKIETEEEGGDFERRRAWDWTIEESEKWDQRLRKKKQTIQNVA FT FSDYHSQASKDYNRGIRDLKPDYEKYDKDKKEEKSKSRSVALYDEAERLDWVSNKPDKE FT HVERLVESIKKQDQRRLKNTKRRGTDEEDHITFINERNRKFNLKLQRFYSKYTKDIKED FT LERGTAL" FT misc_feature complement(29303..29317) FT /note="ctaaccaaagtttag, splice branch and acceptor" FT misc_feature complement(29346..29351) FT /note="gtatgt, splice donor sequence" FT misc_feature 29875..34642 FT /note="nominal overlap with cosmid SPBC4F6, EM:AL031534 S. FT pombe chromosome 2" FT CDS join(30357..30553,30673..30712) FT /db_xref="GOA:O59734" FT /db_xref="SWISS-PROT:O59734" FT /note="SPBC3E7.14, len:78, SIMILARITY:Drosophila FT melanogaster, RUXF_DROME, small nuclear ribonucleoprotein FT f, (101 aa), fasta scores: opt: 364, E():8.7e-21, (71.4% FT identity in 70 aa)" FT /gene="SPBC3E7.14" FT /product="small nuclear ribonucleoprotein F" FT /gene="SPBC4F6.01" FT /protein_id="CAA19017.1" FT /translation="MSFVPVNPKPFLQGLIGKPVLVRLKWGQEYKGTLQSVDSYMNLQL FT LNAEELVDGVKTGDLGEILIRCNNVLWVGESTV" FT misc_feature 30384..30554 FT /note="Match to PF01423 Sm, Sm protein Score 82.05" FT misc_feature 30554..30559 FT /note="gttagt, splice donor sequence" FT misc_feature 30655..30672 FT /note="ctaacgtgattttaatag, splice branch and acceptor" FT CDS join(complement(32585..32632),complement(31297..32403)) FT /db_xref="GOA:O59735" FT /db_xref="SWISS-PROT:O59735" FT /note="SPBC3E7.15c, len:357, SIMILARITY:Saccharomyces FT cerevisiae, YKA8_YEAST, hypothetical 49.0 kd protein FT ufd4-cap1 intergenic region., (418 aa), fasta scores: opt: FT 1005, E():0, (45.5% identity in 330 aa)" FT /gene="SPBC3E7.15c" FT /gene="SPBC4F6.02c" FT /product="homology to longevity assurance protein." FT /protein_id="CAA19018.2" FT /translation="MGNNTSRRSQSQKFKNIPSISAGSFSTMPVQHRGRRRRSKSIVGR FT AAQNAVLRSKEKTWIVPLILLTLLVGWYFVNPNGYIKYGIFLSYPIPGTNPAQYGKGRL FT DIAFCLFYALFFTFCREFIMQEIIARIGRHFNIRAPAKLRRFEEQAYTCLYFTVMGSWG FT LYVMKQTPMWFFNTDAFWEEYPHFYHVGSFKAFYLIEAAYWIQQALVLILQLEKPRKDF FT KELVVHHIITLLLIGLSYYFHFTWIGLAVFITMDTSDIWLALSKCLNYVNTVIVYPIFV FT IFVFVWIYMRHYLNFKIMWAVWGTMRTINSFDLDWAAEQYKCWISRDVTLILLTALQLV FT NIYWLILILRIGYRAFTTNDTHDERSEDEDEEVSDEKSSAKKND" FT CDS complement(33259..34642) FT /codon_start=2 FT /db_xref="GOA:O59736" FT /db_xref="SWISS-PROT:O59736" FT /note="SPBC3E7.16c, SIMILARITY:Saccharomyces cerevisiae, FT LEU1_YEAST, 2-isopropylmalate synthase, (619 aa), fasta FT scores: opt: 1575, E():0, (51.2% identity in 461 aa)" FT /partial FT /gene="SPBC3E7.16c" FT /product="2-isopropylmalate synthase" FT /gene="SPBC4F6.03c" FT /protein_id="CAA19019.1" FT /translation="ILRTIEALRGAKNATVHLYNACSPLFREVVFRNSKQETLDLAIKG FT SKIVTAATKNALESKETNWGFEYSPETFSDTEPDFALEVCEAVKGMWKPSAAQPIIFNL FT PATVEMSTPNTYADLIEYFSTNISEREKVCVSLHPHNDRGTAVAAAELGQLAGGDRIEG FT CLFGNGERTGNVDLVTLAFNLYTQGVSPNLDFSKLDEIIRITEDCNKINVHPRHPYAGN FT LVFTAFSGSHQDAISKGLKAYDERKAVDPVWKVPYLPLDPHDVNSEYAAIIRVNSQSGK FT GGVAYLLKTNCGLDLPRALQVEFGSIVKDYSDTKGKELSIGEISDLFYTTYYLEFPGRF FT SVNDYTLSSNGPQSKCIKCVVDIKGEKKDTPSRVVIEGVGNGPLSALVDALRRQFNISF FT DIGQYSEHAIGSGNGVKAASYVEIIFNNTSFWGVGIDADVTSAGLKAVMSGVSRASRAF FT AK" FT misc_feature complement(33979..34641) FT /note="Match to PF00682 HMGL-like, HMGL-like Score 121.44" FT misc_feature complement(34198..34239) FT /note="PS00816 Alpha-isopropylmalate and homocitrate FT synthases signature 2" XX SQ Sequence 34642 BP; 11363 A; 6381 C; 5999 G; 10899 T; 0 other; gtttgtctac tgaaacctga atttgagacc ggagaagctg gaaaagtgtt ctgagtagaa 60 atatcattgg taaaatcgat gttggcttta ggaatatcgg aagatgttgc tactgaaaag 120 caatcagatt ctggagaacc aacatttgcc atactatctg catacggagc aacacgcttg 180 tttgaagcaa cattagtttg ggtaactttc tcgagttgat catcagtgga ttcagtttta 240 aaggagggat atatatcaat ttgagtattc tcaagtgtct ctggcaaatc taaaggggtt 300 tggcttaatg gacgttccag aaacactttc ttaatttgag cggctgctat tttacttaac 360 tctttgtaag atggaagata cagccgttga tagtcaagaa agcgctgttc ccattttacc 420 attttaccct ggaggacgcg caggattgag tttagtgata aataatcaga agttgaggaa 480 ttaagataaa ttgaatcaaa ttcagaatac aattcagtat agtcacttga aagtaaagtg 540 cgaaattttg aaatttcaga tgtacaagac tcaaatttct caggatcagt aacccaatcg 600 cactttattt ggtttatcct tgaagcaaca gaagacaagc atttttcaat gacacctttt 660 aaacgtttat actccttttc tttcagctct ttaatatatg atggattatt tcgtaaagtg 720 accgatggaa cgaagagttc aaaaatctct attaggtctc tttgaaatcg taaagccatg 780 ttgcaataac cgaaataatg aacatgttgt gccataacac tgtggtcaca gaattcgaag 840 cgatccctta tttgagaatt atagaacatg aattcaagat attttccaaa cgaatatttc 900 catgtttctt cagacataac agtaatgtgt gtattctttt tacagaattt gcagtaactc 960 cacataatta tcttttcttc caaaccaggg acagggcacg aaaaagattc caaaaaaacg 1020 ctgatccgac tatttccatg aacataactc ctgtaatgcc acagcatatc attcgtttta 1080 caatactcac ctccacaact tacattggta ttcaagcatg agtcctctat gtactgacca 1140 agagtgcaat cagtttctcg ataaaattct aatagacaac gttcagggcc aatacaagga 1200 acagaagttt ccttgttaat aatggaatat aacaaaataa tcctttgaga agaaaatgga 1260 gaaaacatga gttttgaatg agagtaataa agtgtccact gcttttctaa aaaatgataa 1320 cgttcatcaa tacaaaagaa tttataggac tcttcgtaac tttcttctac attgtcattt 1380 tcggactgct tcattacgaa tgagccagtt ggtgagtatg gatgtaactt cacatctttc 1440 agtaatttgt tacgaataaa ctggtaataa ttaacttggt ttaataaacg tggaagaggc 1500 tttgataaaa agggtgaaaa cgttaaaaat ctggttttca aagccttggt aatagaagaa 1560 tagtcatctg aggctggtaa gttattgatc aactcaagcg ggctgttgct accttgggtg 1620 ctagaaacac tttgattttc attttccaaa ggtcgcaaac tttgattatc actgttcaga 1680 gatttttttt catgattttg gcttttctct ttatcagctg cagtagaggc aaacgaaggc 1740 aacgatttcc tagacaaact ttgataggtt gtttcaaaaa gctccggcat attcacaaat 1800 ttgtctctta acaaggcaca ttcaagtttg atatgatatg caatcaaaac aacaagttcg 1860 acaatcttct tgaccttgct caactgatta taatcagctc ctcttagaac tatggtgcag 1920 cctaaacgtt ccgagcagcg atcaagtata gcaaacgttt tcctcaaccc tttgttttca 1980 tcgacaacat acgttctgag ttgaaacctg ccgcaagtac caagacgagg acaaagcgac 2040 aatttatcta ttgacgatat tatgtctgca cgacaacatc tagctatgtc atataaaact 2100 gattctttaa gtccatgaaa ggctataacg ccatgttctt caaagtactt caaggcaata 2160 ctggggattt gaccctgagc aaaaactaga ttcggtttaa gcatgcagat tctattgaca 2220 agatttataa tatactcttc ttgctgagag atgattaaat ccaaggataa aattctctgt 2280 tcgtcacaag cgtagtctaa actgaaagtt aaaagagcta tacgaggccg acgaagcgag 2340 cggtccatag atttggacga agcttttttt gagaacaaaa caccattaac aagaaaacaa 2400 tcttgaatgc ttcccccggg aatctttttt atttttacat agctgcggac atcaatatca 2460 tcaccagagc gaatatcagg acctagatcc aaagccattt ttaaaagaat ttttgggaga 2520 caaagtaccc attgcatagg cgaatccaca ccctcatcat ttagcatttg aaagagtaat 2580 tttcccagaa aagtacatac aagctgatta aatgaatcag agaagagaat ccaaggtggt 2640 aaaatacatg tgcttttgga agaggtaact acagaagaag cacgcgactt tccctggtaa 2700 ggaagaggct cttctgttcc accgggatga ttcaccttat caactcgcgc attgaagttt 2760 tcaattaaag cgggaagtcc atcgggaata gtagaagaag gaaaaagata gtcgcaaacc 2820 gttttcggaa gaaaagcttt taaaaaattt gataagtaac tttcattacc gtaacgctga 2880 attgatgcaa cattttgctg gcgttgctta ataattgcac tattggcatg aaaagaaagg 2940 cccaatccat cattgaatag tgattcatcg tcggagtcgg agaaatgatg ataggaattg 3000 cccgaatcgg ccaaaccccg ttcatcagtc aaggaagaac ttcttgaaat aaagggttca 3060 tttattactg tgctcaatcg atcgtaagac gttgctttta tatttggaga aaggttaaca 3120 aatgaaaggc ctctgtcgcc tttgctaaaa tcctcgagcc ggtttctttc atcagccgac 3180 aagtacatat cagagacttt cgctgaggaa aacgctttat tctttcttaa ctttgagtat 3240 gaaggtactt ttccaaaatt gacgggacga taatctgtgg aaacagagct aggaccagca 3300 tcgtaactat ttgtaatggt taaagcatta tatttaccac tttcggaatc ttcaacattt 3360 ataacattcg aatctaaatt ccttttgctc cagtcaagaa agatggaatg gtgagcccaa 3420 ccaggagaat cataattcga gcgactagag ggaatagcta tcattggagc aacttcagga 3480 ggatgaatat tattaggcat ctcaaatgtg ctacttaaat ctccaaatga tgatagtact 3540 tgatcattcg aattaagttc gtccagtgta acaaacggat gttgctccgt aagatctcta 3600 tttttggatt cgtttaatga atgattgaat agctggcttc gagaataatt attaactaaa 3660 attgaagcac atggacgaca cactttgatc gatccttgga gacgaaagat aaatccagga 3720 gcttctttta agcaatattt gcagataatt ttcccacata ttctacaatg atgtttcctt 3780 cgaaataaag taaattccgt ctcacataat gaacagttgt ttgttctttc atctttcatc 3840 caaaattcgc gcgacaacgt actagtcggc aatttcaacg tagtgtggac aacattctcg 3900 gaatctttaa tgatttgctc tgtgcttgat gtatgcaaag tatctaaacg gtgagaggtt 3960 tcaacaggaa aagtgggcga ggctgcggta ggcgtttcga cttctgacat ttgaacagaa 4020 atgcaaaccg aagattaaaa ttatctccgg aaattattgg ttctattaat taagttctat 4080 gaattgtcat gattgttata tcgaaaagca tgtacgttaa acgcagctgt ttgataataa 4140 atactttagg ttttggtgtt gatagaatag tgtatattaa cgagattcgc cgaatttaag 4200 ttttacaaag ccatagcaat acaagagctt tcggctttac tgtagagcta gatattatag 4260 caaacaagaa tttggtttaa tcacacacga aaaccataac attcttaact ttaaactgta 4320 tgttgattac tgaaaaagaa aggtacccta ggctatatat ttatgtgtac ttttttttat 4380 aggaaacatt ggatcaccca aggattagtg gtagtatgga aacactcgct caaggccaag 4440 gagatttaac tacttttagg ttagcgtgtc catgaaccaa tgaactagta atataaagaa 4500 taaaaataga aaggaacaca tctatgaagc ccttgtccct aacatgaaat cacaaaactt 4560 ccgcttaaac aaaccttatg gctcactaat aaaaccaaaa attgttaaga gcatattatc 4620 agatctccgc aaaaggaaga cgatttcatt gccccggtga tttaagactc aaagagcata 4680 cacaacttta tgatatgcta atgtaactcc tgttaattca ttaggagcta cataatactg 4740 ttcttttttt ttgaaaaaaa taaaaataaa tctacacata ttacgataga gcattttgaa 4800 acaacttgtt ttctaattag gaataaaaaa atatttattt atttatttat tttgaaaaat 4860 tgctagagat cacttgctca tcattggaga atcgtaacaa gtggtagtca agatcattaa 4920 aacactgtct gacagctggc cataaattgc ttgatgtgga atttaaatgc tcttttactg 4980 tttagaagac cgtgttcaat tcattatcaa aattcatcaa tccaatggca agcggatcat 5040 taattgcata tgttatgatt gattgttaaa tcaaacaata atatatgctc acaatccaac 5100 aagattggtc tcataaccat ttcgaaacta tcatattaaa atcggaagag acgattttac 5160 ttaatagcaa tttgtttctt agtttgggac ttctcgacct tgggcaaggt gacagtcaat 5220 aggccattac tgaagttggc ctcaatgcga tctgcatcaa tcttggctgg aatagtaatg 5280 gtacgagaga atgagccaaa gcgacgctct gaccagcgtt ggttaccctc ggtgctttca 5340 ttctttctct cattgacgac ttcgccagaa atagtaagtt ttccgctatc ataatggact 5400 tgaacgtcct ctttcttaac accagggagt tctacatcaa cgctaacagt gtctttaccc 5460 tcatgcacat caatcgaagg agacaactcc ccaggaattt ggttgttcaa acgaggggag 5520 taactaacaa agtcagagaa caagtcgttg acagtagggg gaaagccgaa aaaaggttgc 5580 aaagacattt tttaaaattt aaacaattgc gagtaacttg aaattatatg aattcaattc 5640 aaatctgtat ttgttcgatg ctggactagc ggaaggagta cccttattta tacctttctg 5700 ggaagcacgg aatgggatgg atgtcatata ttgtacgatg actcgaattt tctcgtaaac 5760 gttgtgaaag atcacgaatt tgccggagtt tgtactttcg gaacggcgtc ttttgctaac 5820 actcaaactc tgtattgggt ggacttagat gttcgttagt gcttgctcta gaaaagtcca 5880 aatttgccac ttatgcgcca caaccgaggc agattcaaat ataaacttcg gtacgcaagg 5940 ctgtgctatc tttctagaga gatctagaaa ataatcattc tagtagagtt agaaaaatac 6000 tcatttcatt gactgtatat cgtttccttt accttatttt tttttttact ttgtagtcaa 6060 ctaaccaaaa taaaattttt aggacgcatt tagatttgta aataaaccat aacgtaagaa 6120 tttttctttc taatcttatg atttgagcgc tttattggca aagacgtatt ttgtgcattc 6180 acgcaattgt tgctcatgca cttgaaaaca tttcataaat ctataaaact tatgcgactt 6240 cctcttgttc gtcataaaat tgttcttctg caatatctac gttaaaagca tagcaatatg 6300 aatagttaat tcctttactt tacacaattg ttgggttaag ttacgcaaat ttctgcgatt 6360 gttaactttt taaatattca aataataaat atatttgaag gaatcggacg ttctactgta 6420 tcgtcgcacc tcatattaga tgttttttcc atcattgcag taatgctcac ggtagagtgt 6480 ttgatttacg caataaattt cacaagtgac tcaattggaa gatccttaaa attgtggggt 6540 acatcccgtc gcttacgatt tgcggagacg gagagttttc acaacaaaaa acctacgtca 6600 ttatttaccc aacatgagtt ttcctattca tgcgcatatc aatgaaatct atattatcgt 6660 aaagtcaatt tcgtacagct gtcgttttaa tctttagttt agaaaaaagt agctaactct 6720 ctagcaagga aaataaatat tgaggtttat aacatgattc aaccactaca ttcgaaaagc 6780 aaatgaaaaa tttacgacgg aagctatcgc tcttttttca ataaacaaac cctttcctga 6840 attgttgaca aagtttatta ttaattacta ataaacaact atgagaaaag atggggaaac 6900 tgcaaattat gcctaatgac tgccgaatat catgatatta cttccatctt tccattctgc 6960 cgtcttcttt taagtctttt acctaccgaa taatacatga tcaaaatctt actaaaaata 7020 atgtcgttta ataactcatt acatattaca taccgcataa tgcgaattgc aatatccgac 7080 ggttaaaata tagacattta cggtatacaa atgaagttta ccaactcact agacaatgta 7140 aaatacacga cgtactaact tgctttgcta attttgataa aatgaagaat ttcatgaaat 7200 ttaaaagtgg aaaacattaa cagtaaaata tgtataggtc caacaaaact atgataacaa 7260 tgatatatga aactctccga actcatttga aaaataagac aaaagacaac gtctatactt 7320 tagttttttt taatcagaat cattatcatc caatttctca tacaagccgc tatttacagc 7380 ttgttggata ggattagtaa cttgaatagt actatttttt tccaagctac caacgtcagc 7440 caaatatact cgagacatat atatgtattt ttttaaaaaa aaataaataa acaaacaaac 7500 ttaccgttga aacaaataga ataatctttc tgcttctcgc tctttctctt cttggcttaa 7560 ctcaagtctt tgagatttat ttctatttgt gcacatactc ccagtaatag gatcgattgc 7620 aaggttattt tcttcagtat tttcttggcc ccttgaattt ttctggaata ctggtgaagc 7680 ggcttttgaa agtgggctag gaaatggcat agtttcggaa tgttgtgaga tacccatcgc 7740 atatccagct ccaaatattc gtgcaatttg ctgtgaatcc ccgtcgcata gttcatttaa 7800 aagggacgcg tagtaagtgc caatgggctc aacaattggt atagttaaaa gtctcagtaa 7860 aaggcaacgg aagcttttac ccttttgaag actctgtttg cgatcatcgt tagttggaaa 7920 taatagcata gaaaggttct gtttaatgtt aaaaaatgaa agaagagaaa gcagaattgc 7980 taaaatcggt ggcagagtat tttgatactt tgctgctatg tcaaagcaca aatttaggcc 8040 cttttctagg tattctactt cgcgggaaat aagtatggat tgtaaagttt gacaagcaat 8100 ttcagaaaca taaatggctt ggtcaaggga gagcagctgc agattgaaag atagtagagc 8160 attggtagca tgccatcgaa gcggcgaatt aggattgtta tttaaagaac tggcccaaat 8220 ttcaattaca agtagaagaa ttctgaagga agaattagca aaaccagaga taaaggaact 8280 cattaatttt tcaaataaac gtacttttgt tcgtcttcct cctttaagta tgaacgtttg 8340 ctaattggaa aaagcagcct caaaatttca gttaaaacca tttcgttatc ttggctatta 8400 ttagagggcg agctatttag tgtccacatt ttcttcaaca tctttcaata ctgggttatt 8460 tcgaataaaa aaaaagcgtc gatataatac ttacctgtat taactgagtt ctaacctgtc 8520 gcatatctaa gcaaatatca tcggtttgtg tagataggag aatgaataaa aaacgcatga 8580 aaacaactct tctctccaaa tcgtcattct gatcgtgtgt taaaaaagta atgttgagta 8640 agaaggaaga aaatataaaa aaaatcaaat tcaacctctt tgtctgcctt atagacaaat 8700 acaaaggttg aaatcagtga taaaactttt ggggctctta cttcgaaaac agaggtagtg 8760 agttgtttta aggactcatt gtgtacaatt tgtactgaaa tactgggtac ctgtctcaag 8820 caatttgcta acaatttcat caattcaagt gaaacatcct tttcccataa taaacttatg 8880 actctaagta gatggctcca attctaatct gttagcatct gtttcaatat aagacttatg 8940 ctgggcattg atcatcaaag aacgaagata ttgaaacgga aagagatttt gcaattaaac 9000 cactatacct atatcctaaa gtatcagatt attgcctcat aatgtccctg tatcaacctt 9060 cactaggcct ttttcattta gaatctgtac taatatagca tcgatacagt aagaaacctt 9120 gatcccacaa atagccactt accaaagatt ttgcaactac ttttgatgtt tccaattctc 9180 tacaagcttc ttttaattta ataatagtag agatgggtat gttaaaactt tggtttgctt 9240 cgtcatgaaa ttgtgtagca ctttgtgaat agctttctat tcctaacccc aaactttgga 9300 tataagcttc caattccatt ccttttaagc acatgaaata atttgttaat tttaatgagt 9360 tttcttttat ttaagtctcc attaacatca atttatttgc gcttaagatt agtgtactta 9420 aggtcttaca tgactaccta cttcagcgtc aaaagttgta acaacgctga cattcgtaaa 9480 aatggtatca gtcctttaca ctactgtcac cattactgca ctacactatg caatttgctc 9540 tgcgtttaca agatgctcat atttctaaat attagtcaag aaccttttat caacaattac 9600 gcatgaaatt ttttatgctt tatataacta ccctttaatg aaaaatttta gaattatcat 9660 aaaatgaagt tccaccgagc tggttcctca gttcgattat ttaatgataa ttacaattat 9720 aagaatacca acaataggct gctacttata atacctgtgt actgtaatat tagatctcaa 9780 aaaagcttac cgcacttctt cctatcgtta aaaccgatac tagactgcaa ttagtttgat 9840 aacaagtttt ataactttcg atatcaaaat ttcttggttt tacgtgaata aaagaaaaga 9900 atcaaataat gagcttcgta gagtaatttc agccttctta aacgcaggtt tcttatagtc 9960 ctcaaatttt cttgatcaaa ctaacaaact gtttactttt acgtcctcaa gatatgtaat 10020 ttcaaattga aaaattcatt atttacgttt ggaaatatcc attccaaaac attcaacata 10080 ataataagcg tttaactctt ttcctttact ctgtaatgtc cctaacgtaa ccggctaacc 10140 tattacatgc aatttgagcg agttaagcgc ttgatgaaag gtaatataat attcatcagc 10200 aaaaagattc attcttttat agaacttgga ttaaaaaaaa aaagatggtt atttcattat 10260 caatgagaat ggtagcataa aaccaaagtt aaaaacatca attttattgc aagaatgggg 10320 caaatttcgt gtctatgctt gttgggcgtc ttcaagttgt gaagaaagag tagcagatgc 10380 cttgatgatc taattggtta gcataggtga aatgtttaat tacttacctc tatggcttgc 10440 tgcagttcca tacggcgacg acacgcattt atccaatctc gagaaagagc acgaggccac 10500 tgtgaaagtg ataaaagagc acgaacagag ccatcaagat catcttttaa tagatgagaa 10560 cgagcgtctt ccagcgtttt tttcacagaa acaatatcag gagacttaaa tacagcagcg 10620 ggaagttgag acagtatgat gctcttcaaa tgaccaaaaa atccactttc tgtagtgagg 10680 aaacaggttt tgtaaatttc ctttgataac gtgtcaaact tcgtctgcag ctcttctttg 10740 tctaagatcg gcccggagtc cacaattttc tcaataacac gtgatgctaa agcagccaac 10800 tcatcatctt tagtggcttc ttttaatgta tttacgtgtt gacgaacttc agaaagttta 10860 tggaaacgca tgtctttgtt caaatcatct agagtattgc taacatcaac taatctagtt 10920 acacggccgt tttcatgtaa aacaactcta actagttctt gcaattgctg gaatgaattt 10980 cttaactctt gtaaacgtcc caaccttgaa ccacgttctt gttcgacctg ggctttaata 11040 gattgtaagt gtaatttctc caacgtgata gcttgctcag taagttcatt tttcagcttg 11100 gattcaaaaa cacttgcaag cttgaaaagc tcttgttgta gacgagcttc atgaagtttt 11160 tgaagtcgta gtttctcaga ctcaaaggca gattgccatt tttcgtctct cgctataagc 11220 aaagcttcca acttactttc catttcacta actttctcac gaagacgttg ctcaaaaaga 11280 tgctcttgct cttgctgaat tttcgaaagc ttgccatgca actcattagc ttcgtttaat 11340 gaagattcaa atcttaatga ctgatccttt atttcttgtt catgagcatg atctaaagtt 11400 tcagtaatga tgggtatggc agttactgaa agaccagttt cttgatccaa tccaatatct 11460 ttccatacag attcttctgc agtatcctta gtcacttcag aaggtaaatc cactatttcc 11520 acaactaaag actcgggtcg ttctatagtt gtatcttttt tcaccttggt atcgtcgttc 11580 ctactagaat tttgtttctt agatatatta ttggagttct gcttcaattt aggggatgaa 11640 tcatcgactt ttattctgtt accgcctaaa tatttgtatc ctatccatga ttgctcgacg 11700 ttatatagca cttgcttacc aaaaggagta tgctcagcaa agtagtcata aaaatttggg 11760 tctttaaagc aataaacgac gctgcatgaa tagccagtta tgcctaaaag aaagagaaga 11820 agaaatcttt tacgaaattt agaggaattc gatttatttg atgaaccttc ctctggtttt 11880 ggtacaaacg gaattggttc cgtcttgttt tgcttcacat caggaggtaa tgcccttaag 11940 ctggattgga tccaaaacga ctttctgtta atataataag acagagaata aatacataca 12000 cgatattggt gcgttttctg taaagaaaag caacttttaa cagttctaag ctgtcgattc 12060 attgagaggg gagtgtgttt actggttaga acactaagaa ctcaagacgt tgctactcca 12120 aaagctttaa cgtattgtgg tgtaccttac agcagcacca tttgcactac tatctataat 12180 gaacgcaaat tgatgacgcg cttagttacg ctaaacttcg ctatatgcat atattattca 12240 tttaacacta gggatttaaa aagatgttgg gtttactttg tactacgctc actggttaaa 12300 tgaatattta ctaattagct ttgttcgagt gcctatggct tttttggccg tattgaatat 12360 aagtattgct gcagtcaaat agaaagcggc tataaaaact cttcaatttt caattgttat 12420 gaagtctaat aaattacatt tagcaattgt aaattatcag gtttagcact gtatgaaaat 12480 tcatatggaa gagatttaat tataccaata catactcatt ttagtagcat tctgataata 12540 attatgatac atatacatac tctgtaaacg aaaaaagagt aaaaacaatg agcatctctc 12600 ggttaagaaa actctcaggt tcttttatca tttgctgcgg acaaaaatta tatgtactgc 12660 ttggatagct gtgaaatacg tttaaaaaaa gtaaaagaaa gggtaagttg acatttaatt 12720 ggtaactagt taaaaactat aaaggctata atgaagaaaa taaattcaaa acgattaaaa 12780 taaaggaagt agtatacaaa atcacaaata tagagtaaag ttgatctata tgctgaaaaa 12840 actttacaat atattcattt ggtataatct tttctagagg ttacgatttt tgataaacat 12900 tgagcaaaca aatgcgcaga aaaacatgaa tgagacaaac aaaaacgaat agtgaatgct 12960 acccaaaagt gcatccagta ctgtttggcg aatttcttca ggtaaacgat gaacataaga 13020 aatatcttta cgtaagtgat gaagcaattc atcaacgtca aaatctaatg attttctcag 13080 tttaattcct aaaacagttt gcacgattga ggatgatatg gaaacgccta ggacacaacc 13140 attggaccta aacaaatatg aagtagcaat agcagaagct tgaaatgctg acggagaagc 13200 atgaattatg gcgactaaag tagtagtaac agcaatgccg tttcctaaac caccggaaaa 13260 gggataaaca gcatattccc agttaaagtt cgagtagcca taacgaagca tgaaaagggc 13320 agcaacacta ccgaaaaaat aactaccaac ggttattttc ttgtaatttc cggtaagact 13380 aattaccgca cctccaagaa gcgaacccaa actgctgcca ataatcattg gtatcagtct 13440 aatgccagat ttctcagcac cttcattttt tatggattga aaaaaaagcg gcattccata 13500 aatccagcca aagttagcaa cggagtgaaa gaaattgcaa agatatgatg aaaggcaggt 13560 tctctcagta agaacatcca ttggcgccag cggctcaaaa gccacaaacg cttctacgta 13620 aacaaatgaa agatatgaaa tagaagaagc gatcagcaaa gaaataacaa caggatcatt 13680 ccattctcta acatttccac ctaaggtaaa agcacaagtc atcgttgtga caccaataat 13740 tagcaagatc agacctttca aatcaatttt ccgaaatctg gtcatgaaac ttacgtggtt 13800 gtgatgggga agattaagag taaagtaaac acacaaaaag gcgatagcaa ttaagggaac 13860 ctgaattaaa aaaccaattc tccaagtata ttgatcggca aagtaaccac ccactggtcc 13920 gccaaggctt gaaccgatag caaaaaatac atttataatt ccttggtaag ttcctctttg 13980 ttttaaaggc acgatatcgc tcattaaaat gcttacagtc gaattcatgc ctcctccacc 14040 aattccagca atagctcgag ctgctactag ctgccataaa gagcgagaag taccacaaag 14100 gaagcagcct attccaaata cacagtaagc cgccagaaga gtctttttcc tcccatagat 14160 atcgcaaaat tttccgaaca atggttggaa cgcagtgcaa gatatcatgt atgctgtagc 14220 ggtccatgaa acttgactaa actttccaaa ttcggcacca attttcgtat acgtagaggc 14280 gacaatggta ttgtctaaag cagccaaaac aacacccaac aataacgccg gaagaacttt 14340 ggaaacagaa actgtagaca cagtattagt cgtcgctgca tcctggcgat gaggcgaatt 14400 gctaactaca gacactgaag attctggcct acgagggtac tcgttcactt cagcaacatc 14460 cttgttgttt ttggaagaat ctttgataga gtcatatgat gagtttccat ttaatgaaga 14520 cagagagtca ttcaagagag ctgagcgctc tgaacgtaat ccttgacctc tgtttgtatt 14580 aggagatttg gttcttgggt tcgacattcg attaattagc tacaattgga tgaatgcaca 14640 tgaataagta aggagtgttt cgagacgaca aaatctgaaa tttatgaata tatgcgaatc 14700 ctaaatcgta caaaatgaaa gaacttcagt ggtagtgcat ttgttagtaa atgttatgac 14760 tgcctccctt acttaaattt gtatacttct cgctaacatc tattatctta tcatttcggt 14820 aaacaaagtc cggttagata cgggacagtg tgctcggata cgctcccgaa gtctcgtcat 14880 aaatctatag tattatacca acttgcgttt tcaagtcggt tattagcgcc attgaaggct 14940 cggtcaaata taaaaaaatt ggctcttcga aaattttaat atgtagctcc tccaagtaaa 15000 aaaatatgca agtgattgtc attctttgag atgtgtacgt ctcatagata accaactact 15060 gtaaaataaa aacatcaaaa atttgtaatg catatcttaa cttgcaaagg atgccgagat 15120 tggtgaaata aatgaatgcg tttaccaatt tttatttatc ggaaatcctt ttcagtcgca 15180 taaaatcact tggtttacta actgaaacta ttaacttata tgggtttgaa ttttgaaata 15240 catatgttta gttaatttgc tcattgaatg gatctgtaat caaatagatg attatattct 15300 taacaaagca ttctgatcta taagtaaaat tacaagatga acaaattata tctaatctat 15360 atattcaaat taggtgtgag ctcaaacaaa cttgcttgaa aaatagttgc ttctgtgtaa 15420 cttcgcattt gcttcataaa aagtcaaaga atatgaaatg cacctgaaac gcagaatgga 15480 ccctttgttg ataacttcaa gtattttgct taattgtgaa atttaaatac gcaattgttt 15540 cgttcaaatg aattctgaac tttcgaaact cattgttatt attaataata atattttttt 15600 tttgttattt ttacaagcga accgaaattt tgcttttagt gggtatactg attcgtggtt 15660 tattgaccag taataaattc atcaatattt tgtaattatt ttgcagaaaa agtacatgaa 15720 attcttttta agtatatagt aattctcgag attctgtaag gtagaattaa ataccaataa 15780 ttttatgcag ttacctttac tatggtcggc aaaatcaact tatagactaa gtaagtggtc 15840 ctcgtaattt cttttgttta tcccacaaat tcttaaccgg cgtcttacat ctcaaatgat 15900 tacgaaaaaa aagaagcatc ttgctaactg taaatacatg aattagtaaa attcaagttg 15960 agatttctga aaaaaaatag ttaataagta tgcagccctt acgtatgaaa tagtgctaca 16020 taattgaaat gctcaatggg ttaaagattc gctattagaa gttagaaaca taaagctcga 16080 cacaatttta tatctgtgtt tgcactgaag taaatctatg cactttgttc tcatataatt 16140 ataagaatta ttatactcaa atataaagtt tgcagtcctt catattatta gtatcatttc 16200 tttaaagtgt ttacttttag caaaaattat ttccttacac aatatctaga aatctaaaca 16260 agttgtgagt cactttgtta gaaaaaaaaa aaacgtcgaa taatcaggac ggatttaatt 16320 gtaaacatca ctctgattag cataggaaat ctggtctctt tggttttgtt gtttacttgt 16380 cacaattctc aattagtaac tttagaaaaa ataacatttt cttactcaag cactatgaat 16440 tttgtttgat atacgtttat aagagaagga aatatgacct tcatccactt gttttgattt 16500 tattctgaat tgtaattgta cattaggaaa aaccaatgta tatgttatct aactacggag 16560 caatcatttg tacaaatact tccttcagaa aaatttggat gagttgtaat atttattaac 16620 aaggtctaat cttttttaat ccaatcgttc aaaccgtatc tattacgggc gatttcgtag 16680 gccaaaaatt gcatacgagg gactaagact tgttagctaa ataaaataga acattaaaat 16740 atggaaattc atggatcgca taaacgattt tttttaaaaa aatggcactt aaaaaatggc 16800 catgtttctt agaccattaa atttgattcc tagtacatac caaaaatagt cgtttcttgc 16860 tcatactcat cagtattctt aatacgaaga agagtaccaa aattgtaatc gtcaaccttc 16920 ttttcatagc gcattaaaaa tggacgccag gcagcttttc ctttggcgga cttcatttca 16980 tcctcattaa caaaagaagc tgttttaggg tctttaaact cggggaaggt gtttattaaa 17040 tcttcaaaaa tctcatcatc gtatctattc aatagtaagc aatttgaact ttaaattaaa 17100 gatgtaaata tatacttact ttgtcagctt taactcgctt cccttgcgca tttccaaaag 17160 actccagtat atttctaaat tgttattttt tattccatca tattttgctc aacttacgag 17220 cctgttcaac agcttttact gcaaactaaa attttttaaa tcagtacatg ctttaccaaa 17280 actaaatact ttctacaacc acgtacctgc atttcaatct aaaatctgta agtattatta 17340 aataaataat aaccaaggct tacctcggcg gcattttccg cattttccgc atcaattttt 17400 gtacttaaca tttcgaaaaa tattctgttt ctccgttttt actttactgc tgctaagtag 17460 gttgtagtag aaagtgacat taggtaaggt aacaaagagc aagaaaaatt gtaaataatc 17520 aaaacacgaa taaatcacaa aatataagct atgttgctca attactttgt ctaaacacag 17580 ttacagcagg aaaactcaaa aaaatttact caacaaaaaa ttacagtaac ttcttttata 17640 ggaacaacca gttaagtaaa caaataaata aataatttat taaacttatt ttcttcttct 17700 tttgctgggt ttttttagta agctagtact aagcttggtt tttctaggta gattctcaat 17760 agaaattgaa gaagaattcg tcttcggagt taaacttgct aaaaagttat cttcagagtc 17820 tgaatctgaa tcagaggaat ttttgcttgc catcattttc ttccttctaa gaatacggct 17880 ttgtagttca tctgatcctt tagattcacc aaatgcatct gcgtctgcct gaatttcttc 17940 actcattggg ctttgattgc taatctgatt tttaaaagat gaaagagcat tttcaagccg 18000 tttactctta aaatggtatg caactctcgg cgcatataca ttagtattac caccttcaaa 18060 aaactgagtc aaattggact gtgtacccac gaattgcttt ttatgcatgt cttgtataac 18120 cggaagtaaa acttcattag ttcgttgttt tgaccaaccc acagtagcca tcaaaaactg 18180 gcgtaactcg tcaaggtcgg gtatgcccca ttgaaacgat tgcttgctat catccacggc 18240 cggatgaaga taagcttcat caactaacgg attaggaaat tctgatggta aaataatttt 18300 tccaaccaac ttgttaattc tcttttttac tggcgtatta acatcatttt ttgatgcgtg 18360 tccagttgat aaacgttgaa accatttttt aaattcaaaa agtccagtgt caccaggaaa 18420 ttcatgtaaa atctccagtg caagaactgg acctacccta gaaagtccca tagtataatc 18480 acttcccaaa agatgtgcca acttaattaa atccatttga ttcacattaa attctctttt 18540 catatcatcc attaaataga gttcgacaaa tttgttctga ttaaacatat ttcgatatac 18600 ccgagttcca ccaaaaagaa acacgtctga gtcatcagta acaatcccat caaccagctt 18660 tagctccaaa agtttagaac actgggcttc tgcttcttga ggagcaacga tatatggtaa 18720 gccaaataaa cgcagaagtt cttgacattc tttaatcatt acttgagtga cctcatccgc 18780 atcacgtttt tcagaccttt tttgattttt gagctctttc aacctttttt caaaggcctc 18840 ttgattccac tcttcagttt catgtcgttg attgagttct gaaacaaacc gatcatattc 18900 cttttcttct tctgccatcc tgataatcat ttcctcttct tcctcatcta aaagtttttc 18960 aaccacttca ggctctactt tcgaactcaa ggcagcagct cctttatttg gagaggcttc 19020 tttttgaaag tcagttggaa tgctaagtga agggctgctg gtctctaaag taggaagaac 19080 agcgtcaatt gattcggatt tgatatcccc agtatcctta gcattttcgg agctcaataa 19140 atacactgac atggccttat cactagaaac atttaatggg ttggtaactg tgccatcatc 19200 agcttgttct ttcatattct caaagggttc caaaggattg agttcacgta agtctaaatc 19260 tttttcatca tcttttaccg gaagaagagg tgaaataatt ggattttcaa ttccaggttt 19320 agcagcgtct aaatcggatt caatattaac tgttgcatta atagtatgta aatttgtatc 19380 ttccacaagt ttagaattat ccggtgcctc acttggtata tcagttttag aatccataaa 19440 tgtttcagtt ggtttcttta atttctcgaa aaaaatagac tttccccaat ccataggctg 19500 aaaaggtaaa ggatcaatta aatcattggt ttttttctct ctactcgcag atggaagggc 19560 atccataaaa attgaagtcc cattttcagg atgctttttt tccgcgaatg ctaatgaatc 19620 attggaaaca tctccaacat gttcaagttt caaattttcc tcgtcgttaa gaagtgaatt 19680 cattgaatcc tctgcaggaa tatcggtcga caaaatttca aacgtctttt tctcgctatt 19740 caacttatca aactcagaag ccgaaagact aaacagctct tttgattttt tgttttcctc 19800 tagagattgc tgggttgcta attgaagtat taaatcatca gtaacattat aatctgcttc 19860 atctgattgc tgattttccg aaaatgaatt ttcttttatt tcctttaatt tagcggctac 19920 caattctcta gggttcatgc tatgagatcg gctaggtaaa ggcacatcgt agaatgcctc 19980 atcctcgtct tcgtctataa gattgctgct aagttttgta gcctcatcat caataataat 20040 aggttcattg tttgtagatc ctgagataac accgagagcc catccacctt cagcaccttc 20100 gttttttact aaaatatatt ctcggttttt ttcacttact actctagagg gtccaaactc 20160 attcattcca gtaaagtcca ttaatctctg agttaaatcg ttacgttcct tcagtctctc 20220 aatttgaaaa cgagagaaat ccattctatt aggaaacatc tcggaaagtt gttcagagct 20280 taaacccatt cgtaaacgag agcgtaatct tgctgcactt aaaatactat atttatccgt 20340 atcgggtaat gattgaaata attcagagtc aaaatcaata tttgaaaaat caaataaatt 20400 tatatcttca attttagtaa aactagagac atattgtgta agctcatcct gggacataat 20460 tcgagggtcg taactcgacc ctaacttatc aaacgaaacg tccatttcag gtagttggta 20520 tggatcaggc ttcaaataat tttttctttg attaagtact ggcttaattt ctgaattatc 20580 caatgtcata gatgaaggca tttgtctctc attttgaacc gaggcatttg ccaatgcagt 20640 agctttttta ttattttcct ctaaaagcat tgcctgatgc ctcatttgca aagccagaag 20700 tttattggcc gtgaccgtgg cattttcctc cctgtcgagt cttctggctt gtcttttttg 20760 gatagtttgg cgtttcaatg acggcgctcc tccatcaaaa acaaatacag gtttaatccc 20820 aaaaaataat agtttgcata tccttctaaa aaatcctaca acatgactgc ttttcagctg 20880 gtttccttct ttgtcacgta cggcctttaa gaattgataa atccaaattg aagcgtcaat 20940 tgccaaccgt ttgttaacaa gtgtttctag cttgacaggc ctttttaccg gttctaaaat 21000 atcccaaaga cctgaaaccc ccattgcaaa atattatatg cgatgtcaag aagtttcgtt 21060 gtagacgact ttatttttga ttattatacg aagaaatgtg attaaagcaa gcctttttct 21120 ttaccctttt tcttcttttt taattaaaat cgttataaaa gacatgtttt accaacaaag 21180 cgataaaaca agggcatgtg cgatgattga tgctaacact ttagtgtgtg gcacttgact 21240 tgagccaatt accacattaa actgataggg ctgcctaaat catatggtca aaagaagatt 21300 gtctgcattt ggaaatgcct ttttaattta ttttattata tttcggttat gctgctgctc 21360 tccacaaacg agtcattggt gtaaatatcc ggcattgtgt ttgaagtcac cagatacgca 21420 taacgaaaat ttggtatgtg atgcgtacct ttctgtgatt gctaccaaat ctgaagaaaa 21480 agaagctagc aaccctacaa catgggattt cactcccaca aataagtacc aggaaccttc 21540 gtttcacaca aaaacgagtt tgaatggaag tgataccatt tcttctaatt ttttgtcaaa 21600 atatgaatat tccaatggaa caagtactag cgaatttata gattcaatta gcccaccatt 21660 ggtgaacgag acgtctacaa tttcatcctc aaagaagcta gagcaaaact attctgtaac 21720 ggaagttatt gatactaata ttattactag ttcttcggtt actctaccaa tttctgagga 21780 tggttcctct acttcagcag cagctacaat tgattcaaat atagatgaaa agactgttgc 21840 attctcagaa gaaaaaagat tcaactttgc ttcaactgac tgcgctgctg ctgtcattaa 21900 aacaaatcct gaagcagtcg gatcttcttc gattctgacc gaaaacaaag acaaatatat 21960 gctgaacaaa tgttccgctg aaaacaagtt cgtggtaatt gaactttgtg aggatattta 22020 tgtcgataca gttcaaattg ccaacttcga atttttttca agtatatttc gtgatttcaa 22080 ggtcagtgta agcggtaaat atccaaaata cgagtcttct tggatggaat tgggtacatt 22140 tacggcctta aacctaagga ctcttcaatc ttttcatatt gagaaccctc ttatttgggc 22200 gaagtatctt aaaatagagt ttttaactca ttatgggtca gaattttatt gtcctgtaag 22260 cctacttagg gtttatggaa aaactatgat agaagaattt gaagaagcaa atgaagactt 22320 cttagaacaa aaagtgaacg acggaagcgc tattaaagca gatgaaatcc ggaagcctca 22380 agaaagtcct atttttgtgg acgaagaaga taccgatgtt caaagcaaac cagtgagaaa 22440 gaatccatca gtcgagttga atagtacaga caccttactt tcttctactg tgatatctaa 22500 gtctttgagc actgttgtta taggaaatga aacaggaaaa agtgaatcat atcctgcaac 22560 atcaactcgc tcttttaacg atatttctcc atcttcttca tcttcttaca gtaccgctca 22620 aatatctacc tttccttcta atcaggaaag catttacaaa aacataaata agcgtctttc 22680 taccttagaa gaacggaaga aggcatttga tgaaattgta gaaaaaatat taacaaatta 22740 tggtaagcac aatgccaaaa acatgaattt tacgcagcta ttacatgaat tgaactcgac 22800 ccttcaatta gaaatttcga aattgtcgaa aagtgtcgtt aagccgtctt tgtttgctct 22860 ccaagctaaa cttgagcttc tttctgcaga aaatgaatac tttcagagtc aaattacttc 22920 actatatcaa gaatcatctt ttcaaaagcg acttttaatg cttcaactca cggttctaat 22980 cgttttaaca gtgtatatgg ccgtatcgag gcttccagaa aatctgccaa caacccgttc 23040 atcttcaaac aaccctattg aggcttcaag accacctttt tcacgtgacg agcaagatat 23100 ttcgaaggcc aacgattttc gcgttagcgc ttcctcagcg gtttataccg ttggacctga 23160 actactgcaa agaaaaaagc gagatccaaa taccagcata cgcagtatac acgaaagaga 23220 acaagataaa attatacatt ctaggagcca ttcagtatgc taatcataga atgtattgtg 23280 aaacttccat attttttcat aagttaatga tttaaattca tattaaaatt agaaaaatga 23340 attatttatt taaaaactga aaagcatata ttaaagttat ttttttagtt ttgcaaaaat 23400 cataacttta aagagtggca ttgggttata taggttccaa cgacattaat gtacttcacg 23460 gctacgaagc actagtgtga ctagaaattc tcgagtctag aaactaaggc gagtgatacc 23520 cttaagacaa agtatttata tggctactga aattgcaaaa catatttgtt gcggtataga 23580 ttgtaataat gaagctgaca gactgcaatg tcccaaatgt ctaaatgacg gagttaaatc 23640 ttacttttgt ggacaggtaa tttagttttt ctgttagttt acgtatttac taattcaaaa 23700 aaaaaaagga atgcttcagg aacagctggg taatacaaga aaatttcgtg taacgtaaat 23760 taacactagg taatccagaa tattcacaaa catcttcatc gtccaccgaa tgtagaaaag 23820 agaggtacgt acaacaaaag tatatagctt ttattttcaa gcgtttttct aatttgttca 23880 tcagaggatg gaacttacaa tcctttccca aaatttcatt tcgcaggttc attgaaacca 23940 gtttatccgc tttcgcctat acgcaaggtt cctccacata taaaaagacc tgactatgcg 24000 aagacaggag tctctcgtag cgagcaaatt gaaggtcgaa gcttcaaact gaagagattg 24060 acacccaagg agcaggaagg tatgcgtaaa gtatgtagac ttggtagaga ggtacttgat 24120 gctgccgctg ctgccgtccg tcctggaaca actaccgatg aacttgatag tattgttcat 24180 aatgcatgca ttgaacgtga ttgttttcca agcaccctta actattacgc gttcccaaaa 24240 agtgtttgta cttctgtgaa cgaaatcatc tgtcacggaa ttccagatca aaggccactt 24300 gaggatggtg atattgtaaa cattgatgtt tccctttacc ataacggttt tcatggtgac 24360 ctaaatgaga cttactatgt tggagataaa gcaaaagcaa atcctgacct cgtttgcctt 24420 gtagaaaata cgagaattgc tttggataaa gcaattgctg cggtaaaacc gggagtattg 24480 tttcaggaat tcggaaatat tattgaaaag catacaaata gcattactga gaagcagatt 24540 tctgtcgtcc gcacatattg tggacatgga atcaaccagt tatttcactg ttctcctagt 24600 attcctcatt attcccacaa caaggcacct ggaattgctc gcccaggaat gacttttaca 24660 atcgaaccta tgcttactct aggtcccgcc cgagacatta cctggccgga tgattggact 24720 agttcaactg catctggacg ctgttctgct caattcgaac atacactgtt agttacagag 24780 actggttgtg aagttttaac agccagactc cccaattcac ctggagggcc cttaaaataa 24840 attttgatat acccaacatg aattaaaata aaagcagaaa atttttcttt gtatatgaaa 24900 tttataagta aaaggctgaa agaattatat atgagatttc cttcctttaa ccagaataat 24960 gacacttgta caaacacatt gactatatta catacttgct gaaaaatgtg aggtgcatac 25020 ccaaatcaaa agccttcgta gtcgactatg aaccaatttc caacaatcac taacctttat 25080 tacgtaaatc caataatgac tatttacctc tgtcgttcat taagtcttca aaataattag 25140 cgtcactctt ttcgtttggc gcgactttca gaaatacctg acctatcata agcaaggcat 25200 tagcgcgatt tatccttttc tcaagaggaa cagctttatc ataaagaatc ttgtcgctca 25260 cagttcttat cacactttga acttcaaaac gcgttccttt ccatgttgca gataaaactt 25320 taccagttag ttcacgggca gcttcatctc ttttttcttt ggaccattgc tcttcacctt 25380 cttctgcttt tgctaacgca gctgcagagg actgaacatc tacagcacta acaaccgtat 25440 tccaagtgtc tttcaataaa gttccttttg cacaaagact tccccataca cctctgatac 25500 ccaaaaaaga ttgggattgg ataagtatgt tcgcacgttg cacatatgtg gaaccaatcg 25560 catgaagcat ttcattccca aatgactcat cttttagtaa ttctgcttca aattgcattt 25620 tctgtttgaa agcatcagtc actctatcag acatatcggt ttcagtccat atagaaagtt 25680 tatccaaaag atttttacat aatacgtcta ttctttcttg caatagacgg tcggcttctt 25740 tcgattcttc tcgctgaagt tgctttttag actcctcagt atcctcgata gcttttaatt 25800 caggttcttc attaatcatc ttacacaatt cctttaacaa attcaactcg ccaacataat 25860 ctcgaaaaga atccccacca aatagatttt taaaaaattc gaaagcatct tcaaatccag 25920 catccggaac cgcaccaact tttccaagtt tgtcgtactt ctcccttaac tttggatcac 25980 tgagaacttg atatgcttct gctaactata ctttgttatt tcagttctag tacgcccaac 26040 actagttgag gaaatatttg caagtcgctc tctttttcac gagaaactca ctcaatcgta 26100 aaaaagacaa aattttgttt aataaattct taccttttga aatttttctc tagctgcttc 26160 agggttttcc ctgtttttat caggatgata aaggatcgcc aaccgactaa gtttattagc 26220 ttacaattaa cagaaacgta tgcttaccga tatgattttt ttatagtgtc accatctgcg 26280 tcaacagaaa tgtttagaat atcataataa tctctatcga caactctttg aaccataggt 26340 gagatatacg tacgtgtgaa attcgatgta agtatatgcg agttaaaggg tataccgtag 26400 tgaaatgtat aaacttttat aaaattatga gcgctaaaca gttacaaaac atatagaaat 26460 attgtaaatt gtaatagatc actaaattga acgcataact tggttctatg aaaccttccc 26520 agttagcgcc tgcatcaaca aatttacttg cataatgtat gtcgtgaggt atataatagt 26580 aaatgcttaa agtacgagtt atacaaagct acatcaattt tgtaactgaa atataatcta 26640 atttagcagc cacggaagta taagcatttg gaattttaaa aaagagtcat tattaaaaaa 26700 attaaatata aatgagatat gacagatgaa ttggtattaa aaataagaac aaaatttgcg 26760 actttctagt gcaactgatg catgataaat gatatacctt atactaaaca aatgctggta 26820 tgggtacttt cgaaaccttt gaatgagagc atatatcgtc gagaattgca gttgatatca 26880 aggataaaac tacagattca gcaggcgaag gtttccagga agacgccgta aatgaaacca 26940 attataacca tcaataattg ggtgccaaat acgattaaat gaaaataata agacaaaggg 27000 tttatatatt atacattgcg aaaggaaaac gctccgttta cgagcttatt cttctttcac 27060 tggaggagaa ccaaggtact agcaatttga agggcatcag catcagtaat tggcgaatca 27120 ttgataagac cggcacgaaa gcccgcttcc gatttagcta ggtctttaac acaacctacc 27180 ccagtttcat aaaacttccc gaggacataa caagcaggag catggccaag catcgcagca 27240 cggtgtgcat attcaaatgc acgacgcgaa ctaggaaata tatgaccggg taaacctcgt 27300 aaatatagtt tacataaagc aagcatagcg tccgcattac ccttgtcatt ggccaaatga 27360 tagtactgca aagcacgtag cttattctct cgcgccccat atgttccata gaaaaatgct 27420 tctccaacaa ggaaggaact tctgtcatgc cctaaagagg cagccaacat gtacaaggga 27480 agaatgctct tcagatcttg actagttcct cgctgtttat acaattcggc aagttcatag 27540 ggtacaaaat tttgctgaga tgctacctcc ggcattatgt attctaaaaa ttcaattgca 27600 ttttccaagt taccatcctt cttagccttt atagctaagt ccaaaatttg atcaaattca 27660 tgatcataga gtgaaagctc tttcttaatt tcgctgccgg gttgttcctg agaagaaagg 27720 ctagttgcct tttcaagact gatggcacta gcatttgctt cattagtaac acgaagaacc 27780 cgagaagtgt ttggcgcaaa aacaagagga gctaagggat cgaaactaga atcttccttt 27840 ttatggtgaa atttcgaata aaatttgcta agtaaacgct tcgctcgact aacatgtcta 27900 tggataccat gaggttcaag ttcaaaactt cctctagaag aaagagcgtt tgactccgaa 27960 ccagatttgg aaaatgagga atcagaagag tttgaagaga gtgaaggttt agaagcatgc 28020 tttgtaaacc gagagagctt tgcactccag ctgctagaag aacgagagtg tgaactaaca 28080 tcagctgcac tgttcgaaaa gcttgctatg gaaggtgcag tctcaaaagt tgtaagggga 28140 caatctagaa acgataaaac tgaaacatcg tcggacaaag aatcatagct cattatagaa 28200 tcagaggacg aaagtgacca gctgctagaa gagacctctt catgtgcatt attagtctct 28260 ggaagaacat cgcttactgt aggtaacgga cttccttcaa gagctaaagg gctttcttgt 28320 tcaattttaa cagaaacatt atcaacttta gaagcaggat ctgaattaac cagcaatgcg 28380 tctggtaact tcgaaggagt ttcggggatg gacgtggatg caggcatgga agtcacagag 28440 tcgttattac cttaccttca aactgctcat tacccagaaa atgtgcaatc ttcgaatata 28500 aatacttctc gtacatcagg tacctttgac atcctttatc cagccacata aacaggtttc 28560 ggtaaaacca acctacccag tatatgccag ccacgccaga gtactttctt acgttgcgcg 28620 ttgggtttcg gtaaaacaag aaaggctggt aaaagcaaat aaaaaaagca taagatgatt 28680 aaagagccgt acctcgttcc agatcttcct taatatcttt cgtgtatttt gagtaaaatc 28740 tctgaagttt gaggttgaac tttctgttac gttcgttgat aaatgtaata tggtcttcct 28800 catctgtacc acgccgtttg gtatttttta accttcgttg gtcttgtttt ttaatacttt 28860 ccactaaacg ttcgacgtgt tccttatcag gtttatttga cacccagtcc aaacgctctg 28920 cttcgtcata taaagcgacg gatcgagact tgcttttttc ttctttttta tccttgtcat 28980 acttttcata atccggcttc agatctctta tgccacggtt gtaatctttg ctagcttgag 29040 aatgatagtc tgagaatgcc acattctgaa ttgtttgctt tttctttcgt aatcgctgat 29100 cccacttctc gctttcttca atcgtccaat cccaagctct tcgtctttca aagtctcctc 29160 cttcttcctc agtttcgatt ttagcaagct cttcctctgc ctccattcgt tttcgttcga 29220 gtcgccgctc caaagcagga tcaatgcgca ttcgtgaatg ctcttgtact acctctttac 29280 gattttcatg agaagatttc ctctaaactt tggttagccg tacaaaatag ctaagtagtt 29340 aacgaacata ccatttgttc acgaattttt tttagttttt caactcgtgc ttcacgtgag 29400 tgagaaggcg agtccattgt gtttaaaatt ctttgcccct tagttttttc ctctaatttt 29460 taaaaaaacc acaactattc agaaatcaag tttaattgtt gtagtgtgct acgcatttac 29520 tctacacaat tatgtatgaa caaataatta cctcacaata tgaatttacg ttgactatgg 29580 atactgctct attcattgta aacaaaacaa aacaaatgtc acaaggtaag gaaaagtgct 29640 cggttttaaa cctaactata aactcatcgg attttacagg atgttaataa agaaaaaaag 29700 gcctttgatc atgattcatg ttgtgtcttt gctctcagtt ttcttatctt ttttcctaaa 29760 tccagttgga atagattatt gttttatgat tttataattt aaagtaaaac cttgagcttg 29820 ctcctttcac cgctaaaaca tatctaactt ttctgcatta aaatatgggg tttagatcac 29880 ataaagccga atgatatcag taatccaact agcatagtta acatctcatt attgaaaaat 29940 aatttaatga caatatgttt ttagctgtga acatattacc ttatttctgc agtgaaatca 30000 gatcatccac gttatccttt aaaaatagat aaataattat tcgaaagttc aatgacacat 30060 gcgatcaaca gacttagagc ccgtgcccgt gtttaaacat tccattataa aagggaagtt 30120 ttactcaaag aagtgccctt gtttcgaaaa tttcttgcca ttcaaaaaac taaacacttt 30180 aacacagaac aagtcgcagg atttgacgaa ttgatgggat aacgtctttt gccgtaatac 30240 gttatatcct caagtagatg cagaacattc acctcttgca ggagaaacgt acatcttcat 30300 ctctaagcac atcaacttaa acctaacaag tatttggttt ggatttccat aagaaaatgt 30360 cttttgttcc agtaaacccg aaaccttttt tgcaaggtct tattgggaaa cctgtccttg 30420 ttcgtcttaa atggggtcaa gagtataaag gaaccttgca gtctgtagat agttatatga 30480 atttgcaact tttaaatgca gaggagttag tcgatggtgt aaaaacagga gatttaggtg 30540 agattttgat caggttagta aattttaaat gttagaattc aaatttttat cgtgaattaa 30600 atagcacatg ataattcaat ttcgaaacac atgttagttt gtttttgtct tatactaacg 30660 tgattttaat aggtgcaata atgtcctttg ggttggcgag agtactgttt aataatgaca 30720 agtcgatata taaggctgaa ggctaagaat ttgtatttaa ttgattaaaa aactgagatt 30780 gtttttcaac gttgcatacg catgacttct caacatatcc tccctcgttt gttgtatgta 30840 ttcggttata aatttggatc catacaaaag tgcaaacatt cctcttagat ttattggata 30900 ttgtacttgc ataaaaatta ctcgttagtg attggaatta tgcgtatata tacttttcat 30960 ggagtgacct aattagaatt gaagtttcta ataatttgct acaaagagat ataaccttac 31020 acctttgtag aattttttct cacatccaat ttttcttcat aaaaatctat ttcggcagat 31080 gcatttgttt tatcgagtaa tcggatactg acaatattct cgcttgctct atgtagcctg 31140 aaaaaaaaaa cagtacaacg aaataactat gaacagtaaa catgatataa agtgtgtttc 31200 aaacttcaat taataaagta aaactaacac ttttatgtct catgtgccat ggcaggagaa 31260 attatagtat atgcttaccg aaccgaaaat taaaaactaa tcattctttt tagcggacga 31320 tttttcatcg gaaacttctt cgtcctcatc ctcactacgt tcgtcatgag tatcgttcgt 31380 tgtaaaagct ctgtaaccaa ttcgaagaat caaaataagc cagtaaatgt ttactagttg 31440 taacgctgtg agcaggataa gtgttacgtc gcgcgaaatc cagcacttgt attgctctgc 31500 agcccaatct aggtcaaatg agttaatagt acgcatggtt ccccaaactg cccacataat 31560 cttaaagttt aggtaatgtc gcatgtagat ccatacgaaa acgaaaataa cgaaaatagg 31620 gtaaactatt acagtgttta cataattcaa gcatttggat aaagcaagcc aaatatcaga 31680 ggtgtccatc gtaataaaaa cagccaaacc aatccaagta aaatggaaat aatagctgag 31740 tccgatcaaa agcagggtga taatatggtg taccacgagc tctttaaaat cctttctagg 31800 cttctcaagt tgtaaaatta gtacgagtgc ttgttggatc caataggctg cttctattaa 31860 ataaaatgct ttaaagctgc caacatggta aaaatgaggg tattcctccc aaaaagcatc 31920 tgtattaaaa aaccacatag gagtttgttt cataacatac aatccccaag aacccattac 31980 agtaaagtat agacaagtat aagcttgctc ttcaaagcga cgaagctttg caggagctct 32040 aatattaaag tgtctgccaa ttctcgcaat aatttcctgc attatgaatt ctctacaaaa 32100 agtaaagaat aaagcgtaaa aaagacaaaa ggcaatgtct aaacgtcctt taccatactg 32160 agcggggttg gtaccgggga taggataact aaggaaaatt ccatacttaa tataaccatt 32220 aggattaaca aaataccagc cgacgagcaa agttaagaga atgagaggta caatccacgt 32280 tttctcttta ctacgaagga cagcattttg agcagcacga ccaacgatag acttcgacct 32340 tcttcgtcgt cctctatgct ggactggcat cgtcgaaaac gacccagcag aaatgcttgg 32400 aatctagatg aagaaggcaa ttagctaact tgaaaagatt atatgcttta aatatctaaa 32460 atataaattc ttgcaataag aaatttaact caatacatat gttaaacact cagaaattga 32520 ttaattttca atttacaagt aatcctacca agaactcact ttttcaacga caaattgaac 32580 ttacgttttt gaatttttga gattgacttc ttctcgaggt attattaccc attattgatt 32640 cggaccagca aactgcgttg tgggtgttgt ttggtgctgg tatgctcgca tgagcacaac 32700 aatggtattt gtactacaga ctggtacctc aggagcatat tgctggtagg ggatggaaat 32760 caggcaatat ttttgaaaat ttcgcacata cctaaattgt ttaaaacaac taaattatat 32820 gtctaaagaa aaacaagata cttaaatatg attattgaac aagttgaaat tatatagtaa 32880 taaatgtcaa gactcaattg cattccaacc tcttcagcag caaaaacatt ggataaaatc 32940 gaatatgggc aaaccttaat attccataaa ccagtatata aaaaaagcct taaatactgt 33000 ctactaggca ttcaagatta caatctttca taccaaatat atacactgag acattacata 33060 aatcaaatat aacaaaaaga gattagaaaa atgatagaat taaatattat taatttataa 33120 atatagaata tttttcaacc aaaaaaaaag gtccaactca ttttatgttc cagtctattg 33180 taagccgtta aacccatgtt tttaagtaat agtttttaaa agaaatatgt attgtcttcg 33240 acataggata aggtaagatt acttagcaaa tgcgcgggag gcacgactaa cgcctgacat 33300 gacagccttt aatccggcag aggtaacgtc agcatcaata ccaacacccc agaaagaagt 33360 gttattgaaa atgatctcaa cataagaagc agctttgacg ccgttaccag aaccaatagc 33420 atgttcagag tattgaccaa tgtcaaatga aatattgaac tgacggcgta aagcatcaac 33480 caatgccgac aaaggtccat ttccaacacc ctcgatcaca acccgcgaag gagtatcttt 33540 cttttcaccc ttgatgtcaa caacgcattt aatacatttg ctttgaggtc cgttgctaga 33600 aagagtgtag tcgtttacag agaaacggcc gggaaattcg aggtaatatg tggtataaaa 33660 caggtcgctg atctcaccaa tgctaagctc ctttcctttt gtgtcgctat aatccttaac 33720 aatactacca aattcaactt gcaaagcacg aggtaaatcg agaccacagt tggtcttcaa 33780 cagatatgcg acaccaccct tgccagattg agagttaacg cggataatag cagcatactc 33840 ggaattgaca tcatggggat ccaaaggcaa gtaagggact ttccaaacag gatcgacagc 33900 tttacgctca tcgtaagcct tcaaaccctt agaaatggca tcttgatgag aaccagaaaa 33960 ggcggtaaag acaagattgc cagcataagg atgacgggga tgaacgttta tcttgttaca 34020 gtcttcagta atacgaatga tttcatccaa cttggagaaa tcgaggttag gagaaacacc 34080 ttgggtatac aagttgaaag ccaaagtaac caagtctaca ttaccagtac gttcaccatt 34140 gccaaacaaa cagccctcaa tacggtcacc tccggcaagt tgaccaagtt cagctgctgc 34200 gacagcagta ccacggtcgt tatggggatg gagagaaaca cagacttttt cacgttcact 34260 aatgttagtg gaaaagtact caattaagtc agcatatgtg ttgggcgtag acatttcgac 34320 agtggcagga agattgaaga taataggttg ggcagcagaa ggtttccaca tacccttgac 34380 agcttcacaa acttccaaag caaagtctgg ttcggtgtct gaaaaagttt caggagaata 34440 ttcaaatccc cagttggttt ccttcgattc aagagcattt ttcgtagcag ctgttacgat 34500 ttttgagcct ttgatggcta aatccaatgt ttcttgctta ctgttgcgga agacaacttc 34560 acggaaaaga ggagaacagg cattatacaa gtgaacagtg gcattcttag cgcctcgaag 34620 agcctcaatc gtacgtagga tc 34642 //