ID   SPBC3D6    standard; DNA; FUN; 32329 BP.
XX
AC   Z95620;
XX
SV   Z95620.1
XX
DT   22-MAY-1997 (Rel. 52, Created)
DT   07-MAR-2002 (Rel. 71, Last updated, Version 7)
XX
DE   S.pombe chromosome II cosmid c3D6.
XX
KW   40s ribosomal protein; beta transducin; disulphide-like; dna binding;
KW   DNA repair; dna-(apurinic or apyrimidinic site) lyase; endonuclease;
KW   n-acetylglucosaminyl-phosphatidylinositol;
KW   ribose phosphate pyrophosphokinase; rps25; serine rich; thioredoxin;
KW   transcription factor; trp asp repeat protein; WD repeat; zinc finger.
XX
OS   Schizosaccharomyces pombe (fission yeast)
OC   Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes;
OC   Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
XX
RN   [1]
RP   1-30198
RA   Wood V., Rajandream M.A., Barrell B.G., Hilbert H., Duesterhoeft A;
RT   ;
RL   Submitted (10-DEC-1998) to the EMBL/GenBank/DDBJ databases.
RL   European Schizosaccharomyces genome sequencing project, Sanger Centre, The
RL   Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail:
RL   barrell@sanger.ac.uk and QIAGEN GmbH, Max-Volmer-Str 4, D-40724 Hilden,
RL   Germany.
XX
DR   GOA; O74172; O74172.
DR   GOA; P87168; P87168.
DR   GOA; P87170; P87170.
DR   GOA; P87171; P87171.
DR   GOA; P87172; P87172.
DR   GOA; P87173; P87173.
DR   GOA; P87174; P87174.
DR   GOA; P87175; P87175.
DR   GOA; P87178; P87178.
DR   GOA; P87179; P87179.
DR   SPTREMBL; P87168; P87168.
DR   SPTREMBL; P87169; P87169.
DR   SPTREMBL; P87170; P87170.
DR   SPTREMBL; P87171; P87171.
DR   SPTREMBL; P87172; P87172.
DR   SPTREMBL; P87174; P87174.
DR   SPTREMBL; P87175; P87175.
DR   SWISS-PROT; O74172; R25Z_SCHPO.
DR   SWISS-PROT; P87167; YB12_SCHPO.
DR   SWISS-PROT; P87173; YB18_SCHPO.
DR   SWISS-PROT; P87176; YB1B_SCHPO.
DR   SWISS-PROT; P87177; YB1C_SCHPO.
DR   SWISS-PROT; P87178; YB1D_SCHPO.
DR   SWISS-PROT; P87179; YB1E_SCHPO.
XX
CC   Notes:
CC   Details of yeast sequencing at the Sanger Centre are available on
CC   the World Wide Web.
CC   (URL, http://www.sanger.ac.uk/Projects/S_pombe/)
CC   During 1995 to 1996 about 80% of S. pombe chromosome 1 was
CC   sequenced
CC   by the Sanger Centre.  The sequencing of the S. pombe genome is now
CC   being continued with funding from The European Commission.
CC   Fourteen European sequencing laboratories, including the Sanger
CC   Centre,
CC   are participating in the project.
CC   Protein coding regions (CDS) have been predicted with the help
CC   of computer analysis using the Genefinder program in PomBase
CC   (an ACEDB database) with additional predictions for the
CC   branch-acceptor sites supplied by the program Sp3splice.
CC   CAUTION: It is possible that for any individual CDS we may have
CC   underestimated or overestimated the number of introns/exons or
CC   we may not have chosen the correct splice donor/acceptor sites.
CC   CDS are numbered using the following system eg SPBC25H2.01c.
CC   SP (S. pombe), B (chromosome 2), c25H2 (cosmid name),
CC   .01 (first CDS), c (complementary strand).
CC   The more significant matches with motifs in the PROSITE
CC   database are also included but some of these may be fortuitous.
CC   The length in codons is given for each CDS.
CC   IMPORTANT: This sequence MAY NOT be the entire insert of
CC   the sequenced clone.  It may be shorter because we only
CC   sequence overlapping sections once, or longer, because we
CC   arrange for a small overlap between neighbouring submissions.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..32329
FT                   /chromosome="II"
FT                   /db_xref="taxon:4896"
FT                   /organism="Schizosaccharomyces pombe"
FT                   /strain="972h-"
FT                   /clone="cosmid c3D6  "
FT                   /map="IIR"
FT   misc_feature    1..200
FT                   /note="nominal overlap with cosmid SPBC31A8, EM:AL035584 S.
FT                   pombe chromosome 2"
FT   misc_feature    1..359
FT                   /note="previously annotated as SPBC3D6.01 SPBC31A8.02 very
FT                   hypothetical proteinbut has no met"
FT   misc_feature    1..1640
FT                   /note="putative gene free region"
FT   CDS             1655..2827
FT                   /db_xref="SWISS-PROT:P87167"
FT                   /note="SPBC3D6.02, len:390, SIMILARITY:Schizosaccharomyces
FT                   pombe, O42663, hypothetical 39.7 kD protein., (383 aa), fas
FT                   ta scores: opt: 301, E():9.8e-13, (22.7% identity in 396 aa
FT                   )"
FT                   /gene="SPBC3D6.02"
FT                   /product="hypothetical protein; possibly S. pombe specific;
FT                   Pfam-B_10631; predicted N-terminal signal sequence"
FT                   /protein_id="CAB09122.1"
FT                   /translation="MQLLNSFLGFAASIAVLASSADAAPTLYKRKSKSNTNTAKSVAIL
FT                   DGVGVNNTFGVISYREKFPMDYHIWHTAPSTGKTYLQPWNDAVEPSTYYIDEGTFLRTG
FT                   LKFAYIGDNMDLAFTNHTDWKASKHDDGTHRVDLSQRKPANNFMATQRCGKLDPFGYQL
FT                   KRSKKVFQACGTQVFVGSGRSIDCQWMDSVALNLSRYYGNTEALSSLPLPRNLSADIPA
FT                   KSSRLFPHGIYNFNFSAPNKRMQRFTASEATTVNGQNQSVYLTYDVPYGRSLYYYTSCA
FT                   LEFRFTNEFFPMDVTPNDGSAQFVVYNMSGNPKKQTTSSKGPTRLYEVARFNCTTRGCE
FT                   YTQNIPCPRAGHSHTYELAPASPNTSISWIQSYSPRIGVTLQVYSNANFD"
FT   CDS             complement(3885..5921)
FT                   /db_xref="GOA:P87168"
FT                   /db_xref="SPTREMBL:P87168"
FT                   /note="SPBC3D6.03c, len:678, SIMILARITY:Schizosaccharomyces
FT                   pombe, YATA_SCHPO, hypothetical protein, (809 aa), fasta
FT                   scores: opt: 280, E():1.8e- 10, (32.0% identity in 494 aa)"
FT                   /gene="SPBC3D6.03c"
FT                   /product="Metallo-beta-lactamase family protein; conserved
FT                   in eukaryotes"
FT                   /protein_id="CAB09123.1"
FT                   /translation="MKASLLVPRRALLFGQLLPPKYSWYSVKRWQSQLTFRNKSKRNTN
FT                   RIMLSVVSSLNPDSLIAPLLCVSLDNRKYLIGSMGELTQMKFRSQASNYGGKSVSVFLM
FT                   PPSLQSLNAWGITAGLFGYLQSSGIQNTWGLHAPKPVISIIKKSHHLFSGSPLRLDLNS
FT                   FSSEDNADATNSFYLDEPEFCTIKGNIYSNWSFLSFNSKEAAGVFNADKALALGVPFGP
FT                   SNGKLCAGEAVLSKDGTTWIYPHQVVGPPRKRQYFYVLGCSSLSALNQMSKHVDSFSDV
FT                   YPTCIIHILEKGIWGPEYIKFLSHPKFSRAQHFISCIELASNNPVFQRNKGRNVLPACR
FT                   DFAAFDIKPSTLDTQTQLPENTYVLKEETSMVLYDEQCKISESPSYSPVKLAKKFSSFN
FT                   PLPFENEGYTLDVLGTSATCPTWRRSLSSYSVAIDGTVIMLDCGEGAISQFFRQYGTNT
FT                   EPMLRKLKAIFITHLHSDHYLGLLNVLQAWNKANTNNSMHINIIGPKFLWQWLQRLKSP
FT                   ANLQALLNRIIFIIAKETVTTPLQLTSDLSISSVPSIHINDSYSCIISHTKYGKLVYSG
FT                   DTRPNEKLVKAGIGASLLLHESTFEDDLKHEAIQRQHSTASEALSVAQSMKAKALILTH
FT                   FSQRSYDADFLPPDWTIYPKSKTIYANDGLQWQQFQSKQRETI"
FT   misc_feature    complement(4239..4268)
FT                   /note="PS00152 ATP synthase alpha and beta subunits signatu
FT                   re"
FT   misc_feature    complement(5628..5651)
FT                   /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
FT   CDS             join(6157..6159,6210..6450,6555..6577)
FT                   /db_xref="GOA:O74172"
FT                   /db_xref="SWISS-PROT:O74172"
FT                   /note="SPBC3D6.15, len:92"
FT                   /gene="rps25-1"
FT                   /gene="SPBC3D6.15"
FT                   /product="40S ribosomal protein S25"
FT                   /protein_id="CAB09129.2"
FT                   /translation="MAPKKKWSKGKVKDKAQHATVFDKSIIDRINKEVPAFKFISVSVL
FT                   VDRMKINGSLARIAIRDLAERGVIQKVDQHSKQAIYTRAAASA"
FT   misc_feature    6160..6165
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    6192..6209
FT                   /note="ctaattccatattattag, splice branch and acceptor seque
FT                   nce"
FT   intron          6451..6554
FT                   /note="confirmed"
FT   CDS             join(complement(8855..9005),complement(6886..8804))
FT                   /db_xref="SPTREMBL:P87169"
FT                   /note="SPBC3D6.04c, len:689, SIMILARITY:Saccharomyces cerev
FT                   isiae, MAD1_YEAST, spindle assembly checkpoint component
FT                   mad1, (749 aa), fasta scores: opt: 454, E():1.1e-16, (23.4%
FT                   i dentity in 710 aa)"
FT                   /gene="SPBC3D6.04c"
FT                   /product="predicted coiled-coil protein; possibly involved
FT                   in spindle-assembly checkpoint; similar to S. cerevisiae
FT                   MAD1"
FT                   /protein_id="CAB09124.1"
FT                   /translation="MSSKLTVYQATTSMADSPRDPFQSRSQLPRFLATSVKKPNLKKPS
FT                   VNSANETKNPKLASLEFQLENLKNDLKRKELEFEREQIELQRKLAEEHEQKNSLQLRLT
FT                   LVEKQLEEQSTSYQKEIEEVRNEKEATQVKIHELLDAKWKEIAELKTQIEKNDQALSEK
FT                   NHEVMVSNQALQMKDTNLTNLEKLFADSREQLETKCKELAAAEQQLQELSVHNQQLEES
FT                   IKQVSSSIELEKINAEQRLQISELEKLKAAQEERIEKLSSNNRNVEILKEEKNDLESKL
FT                   YRFEEYRDKVATLELENEKIQTELNSWKSLITNELPTPEAVSNKLVFLQNTNANLGERV
FT                   SSLESQLSNKPANQPLGANEKDAAHITELETKLKELHEQNRRLQRQKSLATQEIDLLRE
FT                   NLKSYDDEEAILSEKNTDMKKLERIEGLVKLVDEYKLKLESMPVSLDVDETSDEVSLQK
FT                   RRRKNEHKDAGYVTELYRKNQHLLFQVKEKTNIEAFLREQIITLESSIATLRQELAQVT
FT                   EINSCRVLQHRSNPTLKYERIKAAQLEMLNAENSALKALLEDKKVDCLPIQSFKIAERK
FT                   ALDLKKEVAEREKRIQRLKEIFSVKSLEFREAVFSLFGYKLDFMPNGSVRVTSTYSRED
FT                   NTAFIFDGESSTMKLVGNPSGPEFERLIRFWCDERKTIPGMLAALTLELLDKND"
FT   misc_feature    complement(8805..8818)
FT                   /note="ctgacaccctgtag, splice branch and acceptor sequence"
FT   misc_feature    complement(8849..8854)
FT                   /note="gtatgt, splice donor sequence"
FT   CDS             join(10265..10340,10378..10616,10939..11280)
FT                   /db_xref="GOA:P87170"
FT                   /db_xref="SPTREMBL:P87170"
FT                   /note="SPBC3D6.05, len:218, SIMILARITY:Saccharomyces
FT                   cerevisiae, Q12382, chromosome xv reading frame orf
FT                   yor311c., (29 0 aa), fasta scores: opt: 509, E():8.8e-29,
FT                   (41.2% identity in 216 aa)"
FT                   /gene="SPBC3D6.05"
FT                   /product="conserved protein; similar to S. cerevisiae
FT                   YOR311C; contains DUF56"
FT                   /protein_id="CAB09125.1"
FT                   /translation="MSTKLTWSQWSKKHEIPRKALHTSIGFFALLLQGCGYHAAQIIPV
FT                   IEIGFIPAFTGDVIRFNWPAFSRLYNRVIGPLMRESEKNAWNGVIFYMIGVWIVLKVFP
FT                   EEIAVMSVLLLSWCDTTASTVGRKWGKYTPKIAKNKSLAGSLGAFVCGVFCCYVYWGLF
FT                   RTGPDSLAAQSRIPFPWLCLINGFIGAFAEAMDVWGLDDNLVIPVVSACLLYLIM"
FT   misc_feature    10341..10346
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    10364..10377
FT                   /note="ttaaccgggtctag, splice branch and acceptor sequence"
FT   misc_feature    10617..10622
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    10925..10938
FT                   /note="ctaactaagttcag, splice branch and acceptor sequence"
FT   CDS             join(complement(13150..13256),complement(11809..12727))
FT                   /db_xref="GOA:P87171"
FT                   /db_xref="SPTREMBL:P87171"
FT                   /note="SPBC3D6.06c, len:341, SIMILARITY:Homo sapiens, KPR3_
FT                   HUMAN, ribose-phosphate pyrophosphokinase iii, (317 aa), fa
FT                   sta scores: opt: 730, E():0, (49.6% identity in 337 aa)"
FT                   /gene="SPBC3D6.06c"
FT                   /product="putative ribose-phosphate pyrophosphokinase"
FT                   /EC_number="2.7.6.1"
FT                   /protein_id="CAB09126.1"
FT                   /translation="MKNLVVFGTESHPKLTESICEHLCLDIGRVELSKFSNGETSVRIK
FT                   QSVRGCDVYIVSPASGQVNDHLMELLIMISACKTASAKKVTAVLPVFPYSRQPDQKFSF
FT                   SGAPLSDLQDAVVPCKKQTGYHPWIAQSGTLVADLLMCSGADHIITMDLHDPQFQGFFD
FT                   IPVDNLFGRPLLKHYISLNIPNYHNAVIVSPDAGGAKRATAIADALGLDFALIHKNRRH
FT                   EYGTSLMLVGDVQNKVAILIDDLIDTAYTLVRAAEFVKEHGASKIYALVTHCVLSGDAI
FT                   ERVKLSCIDKLIVTNTAPQTITPSGCFDIIDVAPTFAEAIRRIHNGESISILYDHNQVW
FT                   V"
FT   misc_feature    complement(12082..12120)
FT                   /note="PS00103 Purine/pyrimidine phosphoribosyl transferase
FT                   s signature"
FT   misc_feature    complement(12255..12854)
FT                   /note="Pfam match to entry PF00492 PRPP_synt, Phosphoribosy
FT                   l pyrophosphate synthetase"
FT   misc_feature    complement(12728..12747)
FT                   /note="ttaacgtgtatttattgcag, splice branch and acceptor seq
FT                   uence"
FT   misc_feature    complement(12966..13247)
FT                   /note="Pfam match to entry PF00492 PRPP_synt, Phosphoribosy
FT                   l pyrophosphate synthetase"
FT   misc_feature    complement(13144..13149)
FT                   /note="gtaaga, splice donor sequence"
FT   CDS             join(14661..14757,14818..14897,14953..15230,15274..15389,
FT                   15433..16232)
FT                   /db_xref="GOA:P87172"
FT                   /db_xref="SPTREMBL:P87172"
FT                   /note="SPBC3D6.07, len:456, SIMILARITY:Mus musculus, Q64323
FT                   , phosphatidylinositol glycan, class a, (485 aa), fasta sco
FT                   res: opt: 1497, E():0, (52.7% identity in 421 aa)"
FT                   /gene="SPBC3D6.07"
FT                   /product="n-acetylglucosaminyl-phosphatidylinositol"
FT                   /protein_id="CAB09127.1"
FT                   /translation="MVSDFFFPQPGGIESHIFQLSQRLIDLGHKVIVITHAYKDRVGVR
FT                   YLTNGLTVYYVPLHTVYRETTFPSFFSFFPIFRNIVIRENIEIVHGHGSLSFLCHDAIL
FT                   HARTMGLKTCFTDHSLFGFADAGSIVTNKLLKFTMSDVNHVICVSHTCRENTVLRAVLN
FT                   PKRVSVIPNALVAENFQPDPSKASKDFLTIVVISRLYYNKGIDLLIAVIPRICAQHPKV
FT                   RFVIAGDGPKSIDLEQMREKYMLQDRVEMLGSVRHDQVRDVMVRGHIYLHPSLTEAFGT
FT                   VLVEAASCGLYVISTKVGGVPEVLPSHMTRFARPEEDDLADTLSSVITDYLDHKIKTET
FT                   FHEEVKQMYSWIDVAERTEKVYDSICSENNLRLIDRLKLYYGCGQWAGKLFCLLIAIDY
FT                   LVMVLLEWIWPASDIDPAVDRVSSTFKISKQNFDESLVLTDPKKKTKIKTACLKDAQ"
FT   misc_feature    14758..14763
FT                   /note="gtatgc, splice donor sequence"
FT   misc_feature    14799..14817
FT                   /note="ctaacatgcattatattag, splice branch and acceptor sequ
FT                   ence"
FT   misc_feature    14898..14903
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    14940..14952
FT                   /note="ctaaacaatgcag, splice branch and acceptor sequence"
FT   misc_feature    15180..15704
FT                   /note="Pfam match to entry PF00534 Glycos_transf_1, Glycosy
FT                   l transferases group 1"
FT   misc_feature    15231..15236
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    15262..15273
FT                   /note="ttaactaagaag, , splice branch and acceptor sequence"
FT   misc_feature    15390..15395
FT                   /note="gtgagt, splice donor sequence"
FT   misc_feature    15420..15432
FT                   /note="ctaacatttttag, splice branch and acceptor sequence"
FT   CDS             join(complement(16928..16991),complement(16811..16879),
FT                   complement(16647..16762),complement(16396..16569))
FT                   /db_xref="GOA:P87173"
FT                   /db_xref="SWISS-PROT:P87173"
FT                   /note="SPBC3D6.08c, len:140, SIMILARITY:Saccharomyces cerev
FT                   isiae, YJM4_YEAST, hypothetical 20.3 kD protein in gcd14-po
FT                   s18 intergenic region., (172 aa), fasta scores: opt: 393, E
FT                   ():2.6e-19, (45.5% identity in 134 aa)"
FT                   /gene="SPBC3D6.08c"
FT                   /product="small nucear ribonucleoprotein (Sm protein);
FT                   RNA-binding; possibly involved in control of mRNA decay;
FT                   similar to S. cerevisiae LSM1"
FT                   /protein_id="CAB09117.1"
FT                   /translation="MNQATQIIPFTTSGSLVDYVDRKVIVVLRDGKKLIGILRSFDQFA
FT                   NLMLQYTIERIYVDDMYGDIDRGVYIVRGENVVLLGELDLDKEYDAVKQLRRMPAEELY
FT                   PLAKLHEEEKKKNIREKGKYLHSVGFSVDGGHDDLY"
FT   misc_feature    complement(16570..16586)
FT                   /note="ctaaatatttcgaaaag, splice branch and acceptor sequen
FT                   ce"
FT   misc_feature    complement(16641..16646)
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    complement(16763..16774)
FT                   /note="ctaactgtgtag, splice branch and acceptor sequence"
FT   misc_feature    complement(16805..16810)
FT                   /note="gtatgg, splice donor sequence"
FT   misc_feature    complement(16880..16896)
FT                   /note="ctaactttaccttttag, splice branch and acceptor sequen
FT                   ce"
FT   misc_feature    complement(16922..16927)
FT                   /note="gtatgt, splice donor sequence"
FT   CDS             join(18050..18222,18355..18473,18512..18852)
FT                   /db_xref="GOA:P87174"
FT                   /db_xref="SPTREMBL:P87174"
FT                   /note="SPBC3D6.09, len:210, SIMILARITY:Saccharomyces
FT                   cerevisiae, Q04603, hypothetical protein., (196 aa), fast a
FT                   scores: opt: 210, E():1.8e-05, (29.8% identity in 181 aa)"
FT                   /gene="SPBC3D6.09"
FT                   /gene="dbp4"
FT                   /product="DNA polymerase epsilon fourth subunit; similar to
FT                   S. cerevisiae DPB4"
FT                   /protein_id="CAB09118.1"
FT                   /translation="MNQDKSKETSELDDLALPRSIIMRLVKGVLPEKSLVQKEALKAMI
FT                   NSATLFVSFLTSASGEIATNNNRKILMPQDVLNALDEIEYPEFSKTLKKHLEAYELALK
FT                   EKRLKLPNVSDVDNRKKAKIDAHDTTPLDEEKDELEEERIAEDIAQNEVEQNIDDVEDL
FT                   EEVNDTLDANAESPQIETIHLTDATGNPIEDSSESDSEESLQLNDSS"
FT   misc_feature    18223..18228
FT                   /note="gtatgt, splice donor sequence"
FT   misc_feature    18341..18354
FT                   /note="ctaacgttacttag, splice branch and acceptor sequence"
FT   misc_feature    18474..18479
FT                   /note="gtatgt, splice donor sequence"
FT   misc_feature    18499..18511
FT                   /note="ctaactattaaag, splice branch and acceptor sequence"
FT   misc_feature    19313..20221
FT                   /note="Pfam match to entry PF01260 AP_endonulease1, AP endo
FT                   nucleases family 1"
FT   CDS             join(19313..20105,20143..20921)
FT                   /db_xref="GOA:P87175"
FT                   /db_xref="SPTREMBL:P87175"
FT                   /note="SPBC3D6.10, len:523, SIMILARITY:Mus musculus,
FT                   APE1_MOUSE, DNA-(apurinic or apyrimidinic site) lyase, (316
FT                   aa), fasta scores: opt: 310, E():3.4e-12, (29.7% identity
FT                   in 306 aa)"
FT                   /gene="SPBC3D6.10"
FT                   /EC_number="4.2.99.18"
FT                   /product="DNA-(apurinic or apyrimidinic site) lyase"
FT                   /protein_id="CAB09119.1"
FT                   /translation="MRILSWNVNGIQNPFNYFPWNKKNSYKEIFQELQADVICVQELKM
FT                   QKDSFPQQYAVVEGFDSYFTFPKIRKGYSGVGFYVKKDVAIPVKAEEGITGILPVRGQK
FT                   YSYSEAPEHEKIGFFPKDIDRKTANWIDSEGRCILLDFQMFILIGVYCPVNSGENRLEY
FT                   RRAFYKALRERIERLIKEGNRKIILVGDVNILCNPIDTADQKDIIRESLIPSIMESRQW
FT                   IRDLLLPSRLGLLLDIGRIQHPTRKGMFTCWNTRLNTRPTNYGTRIDYTLATPDLLPWV
FT                   QDADIMAEVMGSDHCPVYLDLKEEYEGKKLSNFLSHSKEPPLLSTAHHSAYRPSKNIHS
FT                   MFQHFNSMKKNKNNSPTQSENVSASASSGSSPTVSRANSVIDVDAYPPEKRRRKEQSKL
FT                   LSFFAKQKEEKEETNKTEDVSIEVLDNNNESDIGLTVKKKVENGNAWKQIFSERAPPLC
FT                   EGHKEPCKYLTVRKPGINYGRKFWICARPVGELIKNSNAVSEEDTQPFQCRFFIWDSDW
FT                   RANSKD"
FT   misc_feature    19415..19444
FT                   /note="PS00726 AP endonucleases family 1 signature 1"
FT   misc_feature    20106..20111
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    20121..20142
FT                   /note="ttattttttttacaatggatag, splice branch and acceptor s
FT                   equence"
FT   CDS             complement(21058..21867)
FT                   /db_xref="SWISS-PROT:P87176"
FT                   /note="SPBC3D6.11c, len:269, SIMILARITY: low to
FT                   Caenorhabditis elegans., YQ57_CAEEL, hypothetical 24.9 kD
FT                   protein c16c10.7 in chromosome iii., (235 aa), fasta
FT                   scores: opt: 186, E():0.00023, (35.6% identity in 73 aa)"
FT                   /gene="SPBC3D6.11c"
FT                   /product="zinc finger protein; zf-C3HC4 type (RING finger);
FT                   similar to S. cerevisiae YER116C"
FT                   /protein_id="CAB09120.1"
FT                   /translation="MPPAHKRDTNVRNLSAPYNIPSQSARVAAGNAAINRRRSSPVENS
FT                   PGNGFPVSEDATDYPSGTTSENESLPLNRAPRSLREVASELAQEETLPVETSDLNIDVE
FT                   SEVFDLEDINFQNDADDINQRFTYNNHPASVENSLTNVNSIHAQPTTISDMIDLTDETS
FT                   YDPRKQKFEQGKNPSTTNAEIEKEEPSKKQVVPSSQRLADYKCVICLDSPENLSCTPCG
FT                   HIFCNFCILSALGTTAATQKCPVCRRKVHPNKVICLEMMLGSQKKKS"
FT   misc_feature    complement(21130..21252)
FT                   /note="Pfam match to entry PF00097 zf-C3HC4, zinc finger, C
FT                   3HC4 type (RING finger)"
FT   misc_feature    complement(21178..21207)
FT                   /note="PS00518 zinc finger, C3HC4 type, signature"
FT   CDS             22471..25239
FT                   /db_xref="SWISS-PROT:P87177"
FT                   /note="SPBC3D6.12, len:922, SIMILARITY:Saccharomyces
FT                   cerevisiae, DIP2_YEAST, dom34 interacting protein 2.dom34
FT                   interacting protein 2., (943 aa), fasta scores: opt: 1617,
FT                   E():0, (41.2% identity in 985 aa)"
FT                   /gene="SPBC3D6.12"
FT                   /product="WD repeat protein; similar to S. cerevisiae
FT                   DIP2-dom54 interacting protein (possibly involved in
FT                   translation)"
FT                   /protein_id="CAB09121.1"
FT                   /translation="MVKSYTRYEPTEFFGVIASSGCNILGQPSSSAKSVGRAIVGGLES
FT                   VLEWDLKTGQLLSKWKDSDCSAKVTCIANFDEMYAVGYADGSIRLWKDGELLITLNGHK
FT                   SAVTTMDFDKMGTRLASGSMDTDIIVWDIVAETGLFRLRGHKDQITKLLFITPPSKNTA
FT                   EETVVDTDIDSGDMDVDSKSSDSFLLSVGKDSFMKLWDLSIQHCVETHVDHQGEIWAMC
FT                   VSPDAKRCLTAGTGSDVKVWEISFPDDNNFTPTTKAFQQLGTFTRQSRDRPITLAYDVS
FT                   NRYVVFQAHDRLLEVFRLRSSAELEKILNRRRRRKKSEDVSITLKDEYEPFALIRTTAR
FT                   ASSVAWIPGNRTPTLVTSLQNNSIEVYALDVKSEGSAAPLTERASRISAIEIPGHRADV
FT                   RTLALSANHDVILSGANGSLKLWNKKTTSCIRTIECGYVLAASFINNDKCIVSAYKSGE
FT                   LEVYDIASSSLIERIQAHDGAIWDLAVGHDGTYFATASADHTVKLWSLKSSFDFVPGTT
FT                   RKVTTLKLEQTRQIDFTDDVLAVKISPDGRFVAASLLDNTVKVYYLDSLKFFLNLYGHK
FT                   LPVLSMDISYDSKLLVTCSADKNVKIWGLDFGDCHKSIFAHQDSIMEVTFQPDTYNFFT
FT                   CSKDREVRYWDGKSFDLILKLRGHHSEVWALAVGPTFVVSGSHDHSIRLWEQGDDLVFL
FT                   EEERERELEEQYESTLVSSYENAEADGEVKDGDVAAVTKQTIESLKDGEKILEAITIGI
FT                   EDLDQEIQYRLDLLKSPGKARGPRNPILAHLGVSAEEYVLNTFKKIRSSHLDDALLVLP
FT                   FEHVLSLFRFIDIWASRKWSIPLVSRIIFFLLRTYHRQLTTTVKMRPLLNNIRSSLRGS
FT                   LQEERSLIGYNAAGLSYLRHEWELTHNTSLEDIDSTSLEVDGKKRAFSNIV"
FT   misc_feature    22750..22866
FT                   /note="Pfam match to entry PF00400 G-beta, WD domain, G-bet
FT                   a repeat"
FT   misc_feature    22825..22869
FT                   /note="PS00678 Beta-transducin family Trp-Asp repeats signa
FT                   ture"
FT   misc_feature    23032..23076
FT                   /note="PS00678 Beta-transducin family Trp-Asp repeats signa
FT                   ture"
FT   misc_feature    23083..23199
FT                   /note="Pfam match to entry PF00400 G-beta, WD domain, G-bet
FT                   a repeat"
FT   misc_feature    23626..23739
FT                   /note="Pfam match to entry PF00400 G-beta, WD domain, G-bet
FT                   a repeat"
FT   misc_feature    23869..23985
FT                   /note="Pfam match to entry PF00400 G-beta, WD domain, G-bet
FT                   a repeat"
FT   misc_feature    24166..24282
FT                   /note="Pfam match to entry PF00400 G-beta, WD domain, G-bet
FT                   a repeat"
FT   misc_feature    24292..24408
FT                   /note="Pfam match to entry PF00400 G-beta, WD domain, G-bet
FT                   a repeat"
FT   misc_feature    24418..24528
FT                   /note="Pfam match to entry PF00400 G-beta, WD domain, G-bet
FT                   a repeat"
FT   CDS             complement(25609..27789)
FT                   /db_xref="GOA:P87178"
FT                   /db_xref="SWISS-PROT:P87178"
FT                   /note="SPBC3D6.13c, len:726, SIMILARITY:Schizosaccharomyces
FT                   pombe, O74481, hypothetical 64.7 kD protein., (561 aa), fa
FT                   sta scores: opt: 317, E():6.7e-11, (22.9% identity in 498 a
FT                   a)"
FT                   /gene="SPBC3D6.13c"
FT                   /product="putative thioredoxin"
FT                   /protein_id="CAB09115.1"
FT                   /translation="MRSNTFGSVMRISWVVAFITMVQTLVSGVPLTDNDLESEVSKGTW
FT                   FIKYYLPSCGACKRLGPMWDNMVEKAKEQVEGSNFHFGEVDCSKELSSCANIRAVPTLY
FT                   LYQNGEIVEEVPFGASTSEASLLDFVETHLNPDTDPDIPSDEDVLTDEDTEEVASIQPA
FT                   LSTSVSSLSLASTAMSKSASASEFSGSSVTKASKKLTSSPTSVASKKATLSSVSKVAST
FT                   SSLPVTSVSASVDPKSAASKVQDAEFSIQTAPSFPKEKEEKENTEETEESKKSINPTGT
FT                   SKALALDADIDAALTDKEGWFIQFYSSECDDCDDVSTAWYAMANRMRGKLNVAHINCAV
FT                   SKRACKQYSIQYFPTFLFFKEEAFVEYVGLPNEGDLVSFAEEAANFEIREVELLDTVNA
FT                   EKNGDVFFLYFYDDDSAEYLNIIRKTGIQLLGHANLYLTTSQQIAKKYRVVSFPKLIVV
FT                   RDGIASYYPAKMAQDNKDYRRILGWMKNNWLPVLPELRTSNSKEIFNDESVVLFLLNPE
FT                   LDDFDETKRTAQKIATEFLDEEGRTYQSNWQKETDKKNSLVNEAEEKNDLEAIEAAKNF
FT                   HVNGKPSPTRFAWVNGKFWAQWLRKFDIDIEATGPRVIVYNAAQDIYWDETAKGTPISI
FT                   EKDTVFDIIKQVETDPDHLKFKILKKNLGVEYLESYGLNIRVLYMVLGIVTVGILVWYF
FT                   SGRRARTLQRRRHSTPILPVSMRSTGNSGKFD"
FT   misc_feature    complement(26635..26820)
FT                   /note="Pfam match to entry PF00085 thiored, Thioredoxin"
FT   misc_feature    complement(27385..27705)
FT                   /note="Pfam match to entry PF00085 thiored, Thioredoxin, sc
FT                   ore 32.40, E-value 1.9e-08"
FT   CDS             complement(31398..32329)
FT                   /codon_start=3
FT                   /db_xref="GOA:P87179"
FT                   /db_xref="SWISS-PROT:P87179"
FT                   /note="SPBC3D6.14c, len:310, SIMILARITY:Saccharomyces cerev
FT                   isiae, YN23_YEAST, hypothetical 52.3 kD protein, (503 aa),
FT                   fasta scores: opt: 522, E():3.1e-16, (38.2% identity in 325
FT                   aa)"
FT                   /partial
FT                   /gene="SPBC3D6.14c"
FT                   /gene="SPBC30B4.01c"
FT                   /product="hypothetical serine-rich protein (52 consecutive
FT                   serines); contains WSC domain; possibly involved in
FT                   carbohydrate binding; putative proteophosphoglycan;
FT                   subcellular localization of GFP fusion-Membrane"
FT                   /protein_id="CAB09116.1"
FT                   /translation="SDNIAFVAIRNNQCYCGSTLTATEVSSSLCTTPCPGYGSLMCGGD
FT                   LYWSVYLTGNGVLQTTVSSSSVSSTTSSSSSSSPSSSSTTTTTSPSSSSSSSSSSSSSS
FT                   SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSVPITSSTSSSHSSSSSSSSSS
FT                   SSSSRPSSSSSFITTMSSSTFISTVTVTPSSSSSSTSSEVPSSTAALALNASKASNHTS
FT                   LNAGAIVGIVIGCVAFAVVMALCIFLYFYFRRFKIRMSDSANEGKYPSYASELDSRLDP
FT                   AMMNRKSSESLADSQDYSRKILRVTNLN"
FT   misc_feature    31399..32329
FT                   /note="nominal overlap with cosmid SPBC30B4, EM:AL031262 S.
FT                   pombe chromosome 2"
XX
SQ   Sequence 32329 BP; 10045 A; 6041 C; 5901 G; 10342 T; 0 other;
     gatcctttcc tatccactac catttctcct tcctctctcc attgctggtt tttttaccac        60
     actcctttgc actaccttcc acctccatat cttctcggtt cctggcctcc cctcaccaat       120
     cgttgctctt ctcacctgcc gctcgcattc atccatctgc ccttcacgtc ctctcattcg       180
     ttcgtttcgc ctatcctcac cgttgccctc gctccgttgc cttaacattt cccgcatgcc       240
     gtttcgtccc cccctcgtct gacgtcaatc acgcgatcgg ccgtacctct ggacggttcg       300
     tttttcccaa ttcacttccc gaaccctccg tccacggaag tgacgccact gaactataaa       360
     agggcgactc cctcccgcaa attccggttc ttttccaaac cagcgtagcg agtttctttc       420
     tctctaggaa tagcaaattc agttgaattg tttgattcaa cttcctttcc tcatctacaa       480
     tcgtttcttc cttttctttt tctttttttt cgtttctctc gtcttttttt tcttagaacg       540
     atatctaatc gtaaattcat agaaaagtga aactaaaaaa attttctctc ctaacatctc       600
     catcttagac atttgtttgt ttgtttcttt acacttacac acttgtcttt ttacttagga       660
     acatttgttg attattcaaa ctattgctgc gatatttccc caatagtttc ttcccatcaa       720
     tcaatatctc ttcctaaatt gcttagaaaa tttttttctt ttgctttttt tggtccatta       780
     aattcccgct cctttttttt ggtgaatttg ctacgatccc atctttccta gtttggtctt       840
     gatttttagt tttccctttt aatcttagtc ttgacctagt tctcgtttcc cctttccccc       900
     attttttatt tttatttttg tgtaaagagt ccccgttggt ttcttacttt ttattacaaa       960
     aaaaattaat ctgcacttct ccattcacct gaactgcaag tttacttttt tttaatcaaa      1020
     cttctcacaa tttcaatcac tttaactcgt gatttttttg tgtgttcgta caaatttaaa      1080
     aagttagctg tttggtgtta cttttctttt tttgtccact atttcaccaa attccttctt      1140
     ccgatacatt cgcttgtttc gtttccgttg gaatttttct cccgctctta taaaaacccc      1200
     atactaagca acgctgattt tatacacttt gccctgtcat aagtgtgtat tcttctttgt      1260
     tagtctgttt tttttgtttc ttaaatatat agacatacac ccgttgtgaa atcgtgtttg      1320
     gctttcaacc ttgtttttga aatcttacca tctcacatct cttctttttc tttaatcgtt      1380
     tgtacgtctt gagtttcttt ttctcattaa accgtacact ccttggtatt accgtttttt      1440
     ttcttccttt acaaatctcg tttgttttgt taactgagaa aaatctcgta cctcttttta      1500
     actcttccta tctcttttat tagtttgcgg attttttctc tttctcttac actttaatct      1560
     ttgttatttt tgttgtttga cttgtgtgtg tgattcaaaa ccccataatt ctctacactt      1620
     ttaactttct tacaactagt tctctttttt gaaaatgcaa ttgttaaact cttttctcgg      1680
     tttcgcagcc tctatcgctg tccttgcctc ttcggctgat gccgctccta ccttgtacaa      1740
     gcgtaagagc aagagcaaca ccaacactgc taaatctgtc gccatcttag atggtgtggg      1800
     tgtcaacaac acctttggtg ttatctctta tcgtgaaaag ttccccatgg actatcacat      1860
     ctggcatact gccccctcca ccggtaaaac ttacttacaa ccctggaacg acgctgtcga      1920
     gccctctacc tactacatcg atgagggtac cttcttgcgt actggcttga agtttgctta      1980
     cattggtgac aacatggatc ttgcctttac caaccacact gactggaagg ctagcaagca      2040
     cgatgatggt actcaccgtg ttgacttgag tcaacgtaag cctgctaaca acttcatggc      2100
     cactcaacgt tgtggtaagc ttgatccttt tggttaccaa ttgaagcgtt ccaagaaggt      2160
     cttccaagct tgtggtactc aagtctttgt tggttctggt cgtagtatcg attgccaatg      2220
     gatggactct gttgccttga acctttctag atactatggc aacaccgagg ctcttagctc      2280
     tcttcctttg cctagaaacc ttagtgctga cattcctgcc aagtctagcc gtctcttccc      2340
     tcacggtatc tacaacttca acttctctgc ccccaacaag cgtatgcaac gtttcaccgc      2400
     ttctgaagcc actaccgtca acggccaaaa ccaatctgtt taccttactt acgacgttcc      2460
     ttatggtcgc tctttgtact actacactag ctgtgccttg gaattccgtt tcaccaacga      2520
     gttcttcccc atggacgtta ctcccaatga cggttccgct caattcgttg tctacaacat      2580
     gtctggtaac cccaagaagc aaaccacctc ctccaagggc cccacccgtc tctatgaggt      2640
     tgctcgtttc aactgcacca cccgtggctg tgaatacact caaaatattc cctgccctcg      2700
     tgctggtcac tctcacactt acgaacttgc tcctgcttct cctaacacct ctatttcttg      2760
     gattcaatca tactctccta gaattggtgt cacccttcaa gtctactcca atgctaactt      2820
     cgattagact ggcagttgct gggttccctg tccttcattc gtatgcgatg ttgcattcgt      2880
     cttcctttcg taattaataa tggcgtcgct gtgatgcgat ttgaaatttt gtccttgttt      2940
     acgtaatgat gcgtgtgctt gttgtactgg atgagacctc ttctagttta agcgcgcgtg      3000
     cactttacta ttaacctcta tttaccggtt cccccctttt tcccttttcc gcgcatgcgg      3060
     ttggaatgca gttaagttgc tgctaaaatt aataacatgt ttttccagcg acttaaatgc      3120
     tcaatgtagt agatgctcct ttactatatg agggtgcgta aaaaaccgta tttacttgtt      3180
     cggtaaatac tcaccctttt tttctttttc tctactacgt taattacctt ttgccgaccc      3240
     attgaatcat ctttgaaatt ttattacagt aaaacatttg gatactgaat tttcattgtc      3300
     agcttattta gatctttttt tcgttgtttt aatcacttac tatttgttta tatgagacct      3360
     acaacaatat cgtaaaaaca gtgatatata tatatttaag tgttatttaa taactttatg      3420
     tgtatgaatt gttggtagta aaggtatagt taatgttggt ttgtgtgtat aatgtgtcgt      3480
     gtgtacgttg tctttttcag atagtgtagg ttttgtactt gtgatttggt gaactgtttg      3540
     catttagtat tattgttagc gatgttcttt ggttaactag cagtgctagc agttagtaaa      3600
     catatttttg gctttcatgc tagttagttg ctagtattac tttgagagaa gagcaaacga      3660
     tgttcttccc agactacaga catttaaaca tttttgaaaa aatcattatt ttttatcatg      3720
     aaacctatta aacaaagtaa tgccttttgc tctaagagca cctgagaaga gtggagagtc      3780
     tgtgctagtt ttgtttcgta ctcaaaaatg catacgagca gaaaaccttc aaatttaagt      3840
     gattggcatt caactcaaat taaccataca agatattaac agccctatat cgtttctcgc      3900
     tgcttgcttt ggaactgttg ccactgaagg ccgtcattag cgtatatggt ctttgatttt      3960
     ggatatatgg tccaatccgg gggtaaaaag tcagcatcat aagagcgttg actgaaatgt      4020
     gtcaaaataa gtgctttggc tttcattgat tgagcgactg aaagcgcttc ggatgcagtc      4080
     gagtgctgtc gctgaatagc ttcatgtttc aaatcatcct caaaagtcga ttcatgaagg      4140
     agtaaagaag cacctatacc tgctttgaca agtttttcat tgggtcgagt gtcaccactg      4200
     tacacaagtt ttccgtattt ggtgtgcgat ataatacagg aatatgaatc atttatgtga      4260
     atagatggta cagaagaaat tgagagatcg gaagttaact gtaaaggagt ggtaaccgtt      4320
     tctttagcaa taatgaatat tatacggttc aacaatgctt gcaaatttgc tggacttttt      4380
     aagcgctgta accactgcca caagaatttg ggaccaataa tgtttatatg catactgtta      4440
     ttagtatttg ctttgttcca agcttgcaat acattcaata atccaagata atgatcggaa      4500
     tgtaagtgcg taataaagat tgcttttagt ttccgaagca ttggctcagt atttgttcca      4560
     tattggcgaa aaaattggga tatggctccc tcgccgcagt ccagcatgat gactgttcca      4620
     tcgattgcga ctgagtaaga acttaagctt ctacgccaag taggacaggt ggcactagtt      4680
     cctaagacat ccagcgtgta tccttcattt tcaaagggta aaggattaaa cgagctaaat      4740
     tttttagcca gcttcaccgg actatacgaa ggactctctg aaatcttgca ctgctcatca      4800
     taaagaacca tcgatgtttc ttccttcagg acataagtat tttcaggcaa ttgtgtctgt      4860
     gtatccaaag tggaaggctt tatatcgaag gcagcaaaat cacggcaggc tggcaaaaca      4920
     tttcttccct tatttctttg gaaaacaggg ttattactgg caagttcgat acacgagatg      4980
     aaatgttgag cacgagaaaa ctttgggtga gataaaaatt tgatatattc tggcccccaa      5040
     ataccctttt ctaatatatg aattatacaa gtgggatata cgtctgagaa tgagtctaca      5100
     tgttttgaca tttggttgag ggcagaaaga ctcgaacaac cgagaacata aaagtattga      5160
     cgcttcctag gaggacccac tacttgatga ggataaatcc atgtagtacc atctttgctc      5220
     aacaccgctt caccggcgca taacttgccg tttgatgggc caaaaggaac tcctagagct      5280
     aaagccttgt ccgcattaaa cactccagct gcctctttgc tgttgaaaga aagaaaagac      5340
     caattggagt atatattccc tttaatcgta caaaattccg gctcatctaa gtaaaaagaa      5400
     ttcgtagcat cggcattatc ctcacttgag aatgaattaa gatcgagtcg taatggactt      5460
     cctgaaaaaa gatgatgaga ttttttaata attgaaatta caggtttggg agcatgcaaa      5520
     ccccaagtgt tttgtatacc actggattgt aagtagccaa aaaggccagc agttataccc      5580
     caagcgttca gggattgtaa actaggtggc attaaaaata cactgacaga tttccctcca      5640
     tagttagacg cttgacttcg aaacttcatt tgagtcagtt ctcccatgct tccaataagg      5700
     tactttcgat tatcgagaga aacgcatagt aaaggggcta tgagactatc aggattcaaa      5760
     gaagaaacta ccgaaagcat aattctattc gtgtttcttt tggatttgtt tcgaaatgtc      5820
     aattgactct gccatctttt gacactatac caagaatatt tgggcggtaa taattgaccg      5880
     aatagcagcg cccgccgtgg aaccagaaga gaagctttca tcccagcatc cttctgttca      5940
     atatttcagt tgaattgcaa ttattgatgc cgtttggaag tccaagtcaa agtaaggcta      6000
     cacctctttt actttaccta agtctcatta gaagctctag atacttgtta cttgattcga      6060
     attctggtgg taaatttttg ttacccagag gcagtcacaa atgtttggac ttcaaagcaa      6120
     caccagaaac ttgttacaaa ccaaacttca tcaaaaatgg taagtgtgga ttataccatt      6180
     tgcattgagt actaattcca tattattagg cacctaagaa gaaatggtct aagggtaaag      6240
     tgaaggacaa ggctcaacat gccactgtct tcgacaagag catcattgac cgtatcaaca      6300
     aggaagttcc tgccttcaag ttcatttctg tctcggttct tgttgaccgt atgaagatta      6360
     acggctccct tgctcgtatc gccattcgtg atttggccga gcgtggtgtc attcaaaaag      6420
     ttgatcaaca ctccaagcaa gcgatttaca gtatgttaaa gttgattgga ttcgagactt      6480
     tttagtacat gttaagaagt ctcttttctg tgatttacat ttcttgattt ctttttacta      6540
     acattaatgt ctagctcgtg cggctgcttc agcttaaatg acttgagaac gaaaaataaa      6600
     tttattttga aggttgtatt caacaatttc tattgtgcgt atgaattcgt aagatgatta      6660
     aaatggttta gcagttttga ctagtttgta atggtgaaat atatttagcg cttaggccag      6720
     tacaaactgt ttacagtttc attgtatcga cattgaagga tatattgata ttattagtta      6780
     aacaatctat ttcataaaaa agtattactt ttcacatttt gattatgcgt atttgttagt      6840
     gtacatattc atcgcctgta agatgatgct taaggcgtaa gttaatcaat catttttgtc      6900
     aagaagctct aacgttagag ccgctaacat gcctggtatt gttttgcgtt catcacacca      6960
     aaatcgtata aggcgctcaa attcggggcc tgatggatta ccaaccaatt tcatggtgct      7020
     ggattcgcca tcaaatataa aagcggtatt atcttcacga gaatatgtgg atgtaacacg      7080
     aacactccca ttaggcataa aatcgagctt atatccaaaa agcgaaaaaa cagcttcgcg      7140
     aaattccaaa gactttactg aaaaaatctc ctttaaccgt tgaattctct tttctctctc      7200
     ggctacttct ttctttaaat ccaaggcctt tctttcagct attttaaatg attgtatagg      7260
     tagacaatca acctttttat cttccaaaag agctttcaaa gctgagttct cagcattcag      7320
     catctccaat tgcgcagctt taatcctctc atatttcaaa gtaggattgg atcgatgctg      7380
     taatactcga catgagttta tttcagtaac ttgtgccagt tcttgacgta aagttgctat      7440
     ggaggattcc aatgtaataa tctgctccct tagaaaggct tcaatgttgg ttttctcttt      7500
     aacttgaaaa agcaaatgct gattcttacg atatagctcc gttacgtaac cagcatcttt      7560
     atgttcgttt ttcctgcgtc tcttttgtaa tgagacctca tctgaagtct catctacatc      7620
     aagagataca ggcatacttt caagctttag cttatattca tcaaccagct tgaccagacc      7680
     ttcaattctt tccaacttct tcatatcagt atttttttca ctcaaaatcg cctcctcatc      7740
     atcatagctt ttaaggtttt cccttaaaag gtcaatttct tgggttgcca aagatttttg      7800
     tctttgtaga cgtcggttct gctcatgaag ttctttaagc tttgtttcaa gttcggtaat      7860
     atgagcggcg tctttttcat ttgcaccaag cggctggttt gcaggcttat tagacaattg      7920
     actctctaaa ctagaaacgc gctctccgag attagcattg gtattctgta gaaacacgag      7980
     tttgtttgaa acagcttcag gggttggtaa ctcgttagta attaaactct tccaagaatt      8040
     taattcagtt tgaatttttt cattttcgag ttcaagggta gcaaccttat ccctatattc      8100
     ttcaaaacga taaagtttgg actccaaatc gtttttctct tccttgagaa tttcaacatt      8160
     cctattattg gatgatagct tttcaattcg ttcttcctgc gcagctttta atttttccaa      8220
     ctcgctaatt tgaagacgtt gctcagcatt tattttttcc agttcaatag aactagaaac      8280
     ctgcttgatg gactcttcca attgctgatt atgaactgaa agctcttgta attgctgctc      8340
     ggcagccgca agttccttac acttcgtttc aagctgttcg cgggaatccg caaagagttt      8400
     ttcaaggttt gtaagattgg tatccttcat ttgcaaagct tgatttgaga ccattacttc      8460
     atgattcttt tcacttaaag cttgatcatt cttttctatc tgggttttca actctgcaat      8520
     ctctttccat tttgcatcaa gtagttcatg gatcttcacc tgagtggctt ccttttcatt      8580
     tcttacttct tctatttctt tttgataaga agtagactgc tcctccagtt gcttttcaac      8640
     tagagttaga cgcagctgta acgaattctt ctgttcatgt tcttctgcaa gttttctttg      8700
     caactcaatt tgttcacgct caaattccag ttccttccgc tttaaatcat tttttaggtt      8760
     ttctagttga aattctaaag aagctagttt gggatttttt gtttctacag ggtgtcagat      8820
     ccataaacaa acgtcaaata taagtttcac ataccattag cagaattaac agaaggcttc      8880
     ttcaaatttg gtttcttaac gcttgttgct agaaatctag gcaactgtga acgcgattgg      8940
     aacggatccc taggagaatc cgccatggat gtagtcgctt gatacactgt cagcttggag      9000
     ctcatagtga gaaattgatt tttggtatac ctctttaata taatattgac aatatggagg      9060
     acaaattgca tctcagtaat ttattgaaat cagggaatta aagaaaggta ggactgactg      9120
     catatgctca aacaacatac ttgtttaatg atatctaaat taatggaact tattactttt      9180
     tctttttttt taaatcatag accttgttat tattatatta tatatttaat gtgttgaatt      9240
     ccttaatcaa ttttcgatgc acgtgtgaac ataaaagctt ttaagtcttc tagttttttt      9300
     atattgatat tattattatt tatttaaatt gctagaccaa atcgcgtacc ctaaggaact      9360
     tacgtagtct taacataaat tataatagtt tttttttttt tttttttttt tttttttaat      9420
     aaaacttcaa tttgaacaat taaccaataa ctgaaaataa acctgatttt gagcagactt      9480
     attattatta aataaaaatt attacttcta gttcatcaac taaagaataa tggttttcgc      9540
     atttaatttt caaaattgct tggcaatgat ataagctcta aaatggtttc agtttctttt      9600
     aggaatttta ttagcataca tattcaagtt atcattttac tttttaatag aaactttcgc      9660
     gtacttgaga attgtcttta tattttcaat taattctccc atatttgaca acaaaaagcg      9720
     aaacgtaaga gctcacaata gcatctaaag tttcgtaaag tagcgaaatc cacgttgcgc      9780
     tattctgaag gttcagtgac ttataaatga ttctgcattg gctgtatgtc gatgcagtta      9840
     ttaattctct taatatatca tctaaagaat atttacatct aaagccatat agtgtataac      9900
     ccattcgttt tgatactgag tcatcctgcg aatcactttc aaagctatgc tattcatcta      9960
     ggaagtcgag ctcttatatt ggcagtgata aataaataaa ttttttccaa ctgatgaagg     10020
     aaataaatcg gtttcttttg ggactctcag gaagtcattc attctattaa ttttgacttt     10080
     agctcataat gtttacggaa taaggaggaa tagtgcaacg ataaaaaaat agtgagctat     10140
     atgcgagaac attccttgcc tcgcatatac cgattccttg catcacggcc ggtatcgcta     10200
     tttttttttt acccattaga aataccttta gattggaaaa cactactgag cgaatactca     10260
     tccaatgtcg actaaattga cgtggtcgca atggtccaaa aagcatgaaa ttccccgtaa     10320
     agcactccat acttctattg gtaagttgtt tttatgactt ggattaaccg ggtctaggat     10380
     tttttgctct attacttcag ggatgtggat accacgctgc tcaaatcata ccggttatag     10440
     aaattggatt catacctgca tttactggag atgtaattcg ttttaactgg ccagctttca     10500
     gccgccttta caatcgcgtt attggtcctt tgatgcgaga gtccgaaaaa aatgcatgga     10560
     atggtgttat tttttatatg atcggggtat ggattgtttt aaaagttttt ccagaggtaa     10620
     gtaaaagtca ttgtaatgtc tatcattact gttattattc tttaagaaaa aggaagatat     10680
     ggttttcctt gttccaggcg atccgaaggg ttttgttttt tactggacat actactctat     10740
     agaacccatt ttttcacgga gaatgatttt ctattctaag tatttgtcag accaagcata     10800
     ttgttgttgc atagagttta agttagtatt tttgatcatg attactcaaa tctactttgc     10860
     cttgcttgat cttttcctaa cttcaccttc cttcttcttt tacttatata ttatgccata     10920
     gttactaact aagttcagga gatagcagta atgagtgtcc ttttactgtc atggtgtgac     10980
     actactgcct caaccgttgg tcgaaaatgg ggcaagtata ccccgaaaat tgccaaaaat     11040
     aagagtttgg ctggaagttt gggcgcattc gtttgtggtg ttttttgttg ctatgtgtac     11100
     tggggcttgt ttcgtaccgg tcctgacagc ttggccgctc aaagcagaat tcctttccct     11160
     tggctttgct tgataaatgg atttattggt gcctttgcag aagctatgga tgtgtggggt     11220
     cttgacgata accttgtaat tcctgtcgtt tctgcctgtt tactatattt aatcatgtga     11280
     taaccatgtt cttttatact gacattcttt tgttttttcc attcgtcctt tcccgaccac     11340
     gtttgaaaaa ttattgaata tagttatgtt ttgttgattc gctcctccat ttatcaccat     11400
     ttctattgtt catctttttt ccgtctaacc agtatgcgta catactgtta aaatgtatag     11460
     aaatacctac aagcttcatt acccagacaa ttttaggctt tttgtatgaa acatgacgaa     11520
     atcgtgcaat tagactgcct atatagtttc tacatagctt gtacatatat aatggtcgtg     11580
     aagaacctta tatttagcag ttttacacta gagattagct aagttgaaat tagttttagg     11640
     aaattagctt gataatcatt ttgtcaactc aaagtaaata ataattattt ccaatgtaac     11700
     tgtctaaagt taaagtaaag aaaaaggaca attgatagta tcaaaaaaaa tcggatagtc     11760
     ttaagccaac tagatcaaaa caaattaaat aatatgaaca acgtacagtt aaacccaaac     11820
     ttgattgtgg tcatacagta ttgaaatact ctcaccattg tgtatgcgac gaattgcctc     11880
     cgcaaaggta ggagcgacat cgattatgtc aaaacatcca cttggtgtaa tagtttgagg     11940
     agcggtgttt gtaacaataa gcttgtcaat gcaagaaagt tttacacgct caatagcatc     12000
     tcctgataaa acacagtgag tgacgagagc atagattttg ctagctccat gttctttgac     12060
     aaactctgct gctcgaacta gtgtgtaagc ggtatcaata agatcgtcga tgaggatggc     12120
     gactttgttt tgtacatcac caacaagcat caaagatgtt ccgtattcat gtcggcgatt     12180
     cttatgaatt aaagcaaagt ccaaacccag agcatcagca atagcagtag cacgtttggc     12240
     accaccagcg tcgggagata caattactgc gttatgataa ttcgggatat taagagaaat     12300
     gtaatgttta agtaatggtc ggccaaaaag attgtctaca gggatgtcaa aaaagccctg     12360
     aaattgggga tcatgaagat ccattgtgat tatatggtca gcaccagagc acataagcaa     12420
     atcagctact agcgtgccgg attgtgcaat ccatgggtga taaccagttt gctttttgca     12480
     tggaacaacc gcatcttgca agtcagataa aggagcaccg gaaaaggaaa atttttgatc     12540
     aggttgacga ctatatggga atacaggaag gacggcggta acctttttag cagatgctgt     12600
     tttacaagca gaaatcataa ttaacagttc cattaaatgg tcgtttacct gtccagatgc     12660
     tggactaaca atataaacgt cgcaaccacg aacggactgc ttaattctca ccgaagtctc     12720
     gccattgctg caataaatac acgttaatat aatcaaatag aaaaacatag atagatgtga     12780
     taaagaggtg gaatcaaaaa tggaataaga gtatgcattc aaagatgatg ctgccaaatc     12840
     tttatcagtc actaaaaaca ttaactaaat agagactaag atcaaataat tatgaattaa     12900
     acataaagta aaaaccaatt aacaattaat ggactgaaag tgcgagtata aaactgtcag     12960
     taggggcaag ctactcgact atctaaaatt tttgatagct atcgacccgt atcatggttg     13020
     ggtaaaacgg catactttca gtagtgactt tagcttttaa agaaaatcat tataaataga     13080
     agatttatag gcaactccaa ccctcccaat tgctacaaac tcttcgaaca ctcaaatgta     13140
     ctttcttacc taaactttga aagttcaacc cggcctatat caagacaaag atgttcacaa     13200
     atactttctg taagcttggg atgcgattct gtaccaaaaa caaccaaatt tttcattgtt     13260
     ctgttttagg tgaaacaacc ttgttcaggt taaatagctc ttccaaactc atcgaaaaaa     13320
     cctctgtttg gtatgtccgg ggaaaagcct cggcaaccac aacttgggat agtaggttaa     13380
     aaaaaggcgc tggaatgttt tagtttaaaa aaataaaact tttttaaact taagaaccat     13440
     ccctacaatt tttgatcaga tcaggagtgg tcttaatgac ttcgacttga tcgtccaaat     13500
     ttagcttcct tttgcagcta tttcgcttga ttttcgacat cagcaagtag atttaattaa     13560
     tatgataggt gtaatttgta acttctattt taagaagatt tgaataacca acgttgatat     13620
     tacggtcaat aagaagtcca aacaagttca tattgaggag gacagcataa gcacacttag     13680
     ctaggcgtca aatttgtaaa attcacgaaa ataaataata tccgtacaat ctccatcttg     13740
     gtctgtgttc gcctttatgg taatcaggtt tacaagattc acacatcaaa aaaataccac     13800
     atttaaggtg tttttctttt tgacaggatt acctgtttca aaagaagtgg atatatgctc     13860
     aatgtgaaat ggagaaaatg gtcttgaatc attgttgaat agattggtgc agattgattt     13920
     taatactgta aactgtcgta aactactgtt tcatccaatt gtcttcacct atagaattat     13980
     tttttttttt aaaaaaaaag caactaaggg ctgcagaacg attttgacaa ctcaagcact     14040
     tcaagcgata cttcctcctt ctcaacatta aatagcttgg caaatatttg tgagaataat     14100
     ttgccgtaaa gcagcctctc tcaaagtctt atttaaagta aacttagggt gttcttatac     14160
     gttaaagaat tgttaaatcc tactctgttt acttctttga tgtcagaaca cgattttaag     14220
     tcattgcttt tcatagaaat taatatgttt attatttaac tttcaaaaca cttctgtacc     14280
     tcaattgact gtgaaaggct gatttcattt gggactaatt ttgttgttct tacactcacc     14340
     caaatttcta ataatatgcc attgaagagt aaacaactcc caaagtagat taaaaaaaac     14400
     caaaaatttc tttgaatgaa taaaaaagtt taaaattcat ctaaaatggg atacagggtc     14460
     gcgtatgttt tgaaatgcaa ctttcacaat caatattgtt tgttaaggag attttcttag     14520
     tacaaaatga agcctatagc attttttatt ttttaacatt cttatgataa tatactggct     14580
     tcaataagct tctataaatc accttttctc ttagattgaa atcccaacgt tcaatagatt     14640
     gctaactttg tatgcttaga atggtatcag acttcttctt tcctcaacct ggggggattg     14700
     aaagccatat ttttcagctt tctcaaagat tgattgattt agggcataaa gtaattggta     14760
     tgcgtttagc cttatgataa tgtcaacttg tacatgctct aacatgcatt atattagtta     14820
     tcacacatgc ttataaggat cgagttggcg tcagatactt aactaatggg ctaaccgttt     14880
     actacgtgcc gttacatgta agtttttaat tgaaattttg atcgcgcata gcgttgaaac     14940
     taaacaatgc agactgtgta tcgtgaaaca acatttcctt cctttttttc cttttttcca     15000
     attttccgca atatagtcat tagagaaaat atcgaaatag tccacggtca tggcagttta     15060
     tcctttctat gccatgatgc tattctgcat gctcgtacaa tgggcttgaa aacttgtttt     15120
     accgaccact ctttgtttgg ttttgcagat gctggcagca tcgttacaaa taagttatta     15180
     aaatttacga tgagcgatgt aaatcatgtt atttgtgtct ctcacacttg gtaagtatct     15240
     catgagcaag tatttaaatt attaactaag aagccgcgaa aatacggtgc ttcgtgcagt     15300
     tctaaatcca aaaagagtat ccgtgattcc caatgcctta gtagcggaaa actttcagcc     15360
     agacccatct aaagcttcaa aagatttctg tgagtttttt cgtttattaa ggaaaaaatc     15420
     taacattttt agtaaccata gtagtaatct caaggcttta ctataacaaa ggcattgatc     15480
     ttttaatcgc agttataccc agaatttgtg cgcaacaccc taaagtacga tttgttattg     15540
     ctggcgacgg acccaagtca atcgatttgg aacaaatgcg agaaaagtat atgttacagg     15600
     atcgcgttga aatgcttggt tctgtaagac atgatcaagt tcgtgatgtg atggtcaggg     15660
     gtcatattta tttacatcct agtttgaccg aagctttcgg cactgtttta gttgaagccg     15720
     caagctgtgg tctttatgtg atttctacaa aagtgggagg tgttcctgaa gtcttgcctt     15780
     cccacatgac acgattcgcc cgtcctgaag aggatgattt agctgataca ctttcgagtg     15840
     ttattactga ttatcttgac cataaaatca aaaccgaaac tttccatgag gaggttaagc     15900
     aaatgtactc gtggatagat gtcgcggaaa ggacagaaaa ggtttacgac agtatatgtt     15960
     cagagaataa tcttagacta atagaccgtc taaagcttta ttacggatgt gggcaatggg     16020
     ctggtaagct attttgttta ctcatagcta tagattatct tgtaatggtt ttactagaat     16080
     ggatttggcc agcatctgat attgacccag cggttgaccg cgtatcctct actttcaaaa     16140
     tttctaagca gaactttgac gaatctctgg tattaacgga ccccaaaaaa aagacaaaga     16200
     taaaaactgc atgtttaaaa gatgcacaat gattactaaa ctttgaacga acggtaatgg     16260
     gattatgacg attcatgtct taaaaattac attacatcca tttaaaaggg gaataaacag     16320
     cggtcgagat agctttctat cgtgactgta aacaaacggt atagcaatat tgtgataaat     16380
     ttgttcaacc gttgtctaat acaaatcatc atgtccgccg tcaacactaa agcctacaga     16440
     atgaaggtac ttgcccttct cacgtatatt tttcttcttc tcttcttcat gaagcttcgc     16500
     caaaggatac agttcttcag caggcatacg tcgcaattgt ttgactgcat catactcctt     16560
     atccaaatcc ttttcgaaat atttagccca cgttcaaaga aatttataaa gatgctcgaa     16620
     tattttatgt tacaaacgaa acttaccaat tcacctaaaa gcacgacgtt ctcgccccga     16680
     acaatataca cacctctgtc tatgtccccg tacatatcat ccacatagat cctctcaatc     16740
     gtgtattgca acattaaatt tgctacacag ttagtaaact cacttatgcg cctattcacg     16800
     caaaccatac caaattgatc aaaggacctt aaaattccaa tcagtttttt tccatctcgt     16860
     aaaacaacaa tcacttttcc taaaaggtaa agttagatca aggaaaacat tggaaaaaac     16920
     accgtactgt ctacgtagtc aacaagtgac ccagaagttg tgaatgggat aatctgtgta     16980
     gcttgattca ttcagctatt atttggatgt agcataaact aataatttaa tttagattta     17040
     actttctatt tcttttataa acgcctgatg actttatttg agtgttttcc ttaaaaaacg     17100
     agttcgagga gatggttaga agcaagtgct ctgaggtcgt caaatctgga atcctaaatt     17160
     ctccctgttt aaccctaaaa gtgcttctga agtttaaatg ttattcgttt gttatgtttt     17220
     tttgctaatt gtaaattaaa ttatttggtt tttccatttc taaacttgcc catcattgaa     17280
     tgttgtaatc tgactttcta gttataaagg gaagtcggtc ttcacaaaaa ttaaagaaca     17340
     aaaacatgta tatttttgat cacagattgt aaaaagggaa tctaattata ctcaagctac     17400
     ctaacaattt ttcagcatca taagcggatt agttcattga aaggctcaac attttgcgaa     17460
     gaacagaaat aaataatttg atgattttta tcaattccaa aatcgaactt gtaaaaatgt     17520
     tgccaatccc atttgtaata tccctattct gagctatttc gactgagaag agattgccta     17580
     ttattctctt agaacgttca ttgaacgttt ttggagtgtt ctgaaaaaag ataataaatt     17640
     tagttgtttt tatctattaa ttacaatcaa aaatcgagcc tttaataatg tattgtatgg     17700
     ttatcaaaaa gctttattta tttctaacaa cgctaaaaaa cttttttttt tactcattta     17760
     atataaacaa aacagtacaa ctatttagtt ttaagaaatt tgatagcatt tctacaaatg     17820
     tttcaactct aaggctctct cggattctgc tcataacgca cagatagtgt ttagtgaaaa     17880
     ttgacagaaa taggcgactc agtgaattta ttatacatta attagctaaa aagaagcaac     17940
     cgcctttctc tgtgattatc gtttggtgac cataggatga tatttggatt ggatttataa     18000
     aagacttgta tacagcgttt gtaaaagatc tagcggctgg aaaatcaata tgaatcaaga     18060
     taaatcgaaa gaaacttccg aattggatga tctggcgctt cctcgatcga tcattatgcg     18120
     attagtcaaa ggtgtcttac ctgaaaagag tcttgtacaa aaagaagctc tcaaggctat     18180
     gatcaattca gcaactcttt ttgttagttt tctaacatcc gcgtatgtaa tctatataac     18240
     tatataacca tattgaaggg cttgtatgat gaaagaattt attatataat tgccaatttt     18300
     attttcttct ggaaacactt tgtatatgaa tgaataaaga ctaacgttac ttagttctgg     18360
     ggaaattgct acgaataata acagaaaaat tcttatgcct caagacgttt tgaatgcgct     18420
     cgatgaaatt gagtatccag aattctctaa aacgttaaaa aaacatctcg aaggtatgtt     18480
     tcttactctg tacttcttct aactattaaa gcatatgagc ttgccttgaa agaaaaacga     18540
     ttgaaactcc ctaacgtatc agatgttgat aacagaaaga aagccaaaat agacgcgcat     18600
     gacactactc ctctagatga agaaaaagac gaattagaag aagaacgaat tgcggaggat     18660
     atagcacaaa atgaagttga gcaaaatatt gatgatgtgg aggacctcga agaagtgaat     18720
     gatacattag acgcaaacgc agaatctcct caaatagaaa ccattcatct tacagatgct     18780
     acgggaaacc caattgaaga tagctctgaa tccgactcag aagaatctct tcaacttaat     18840
     gattcttcgt aattactgtt ggttaaatgt atatgaagat tgtcaatagt cctaacttac     18900
     atggagagct aatcatattt ttttacacga aaaactaaac cttctttatt ttttaatgga     18960
     ttttttggat acctgttaat accccaattt acatccttgt atccaaacat agctttttta     19020
     aacagcagtt tgagataatg tctttctagc acaacatgta tactcgttta atgacatata     19080
     tttagaaaga atcattagat tgtttacagt tgtaactcaa tattagtcaa tctagaattt     19140
     ttttgaaaat caacattcaa tagggagaag gtcgaaaaga aaagaaaaag ttcattctcg     19200
     aattaaacaa atgcatttta ttttccatca gattaactta tgtcaacaat tgtaaattca     19260
     aaagtctgtc gcctttacct tcgcacactt tctctacgta aaaattataa gaatgcgaat     19320
     tctaagttgg aatgtgaacg gtatacagaa tccattcaat tattttccat ggaataaaaa     19380
     aaattcctac aaagagatat ttcaagagtt acaggctgat gtaatatgtg ttcaagaatt     19440
     gaaaatgcag aaagacagct ttcctcaaca atatgcagtt gttgagggat tcgacagtta     19500
     ttttacattt cctaagatca gaaaaggcta tagtggggtt ggattttatg taaaaaaaga     19560
     tgttgctatt ccagtgaaag cagaagaggg aattactggc atcctgccag tacgaggaca     19620
     aaaatattca tattcagaag caccggagca tgaaaagata ggatttttcc caaaagacat     19680
     tgacagaaaa actgctaatt ggattgatag tgaaggaagg tgtatattat tagattttca     19740
     gatgttcatc ctaatcggtg tttactgtcc agtaaactct ggagaaaata gactagaata     19800
     tcgacgggcc ttttataaag ccttacgaga aagaattgaa agattgataa aggaaggaaa     19860
     tcgaaaaatc attctcgttg gggatgtgaa tattttgtgt aatcctattg acactgctga     19920
     tcaaaaagac attattcgag agagtcttat tccaagcatc atggaatcaa gacaatggat     19980
     acgtgattta ttactaccaa gcaggttggg actactgttg gacattggcc gtattcaaca     20040
     tcctactcgg aaaggaatgt ttacatgttg gaatacaaga cttaatacaa ggcccacaaa     20100
     ttatggtaag ttctgaattg ttattttttt tacaatggat aggtacgaga attgattaca     20160
     ctttggcaac acccgattta ttaccttggg ttcaagatgc agatattatg gctgaggtca     20220
     tgggttcaga tcattgcccc gtatatttag atttaaaaga agaatatgaa ggaaaaaagt     20280
     tgtccaactt tctaagtcac tcaaaagaac cacctttact atcaacggcg catcattcag     20340
     cctatcggcc atcaaaaaat attcattcaa tgttccaaca tttcaattcg atgaaaaaga     20400
     ataaaaacaa ctcacccact cagagcgaaa acgtatctgc ttctgcgtcc agcggctcct     20460
     caccaactgt ttctcgtgca aactctgtca tagacgtcga tgcctaccca ccggaaaaga     20520
     gaagacgaaa agaacaatcg aagcttcttt cattttttgc gaagcaaaag gaagagaaag     20580
     aagaaaccaa taaaacagaa gacgtttcga ttgaggtcct tgataacaat aatgaatctg     20640
     acatagggtt gacagtaaaa aaaaaagtag aaaacgggaa cgcctggaag caaatattca     20700
     gtgaacgagc tcctccactt tgtgagggtc acaaggaacc ttgcaagtat ttgacagtga     20760
     ggaagccggg aatcaattac gggcggaagt tttggatttg tgccagaccg gttggtgaac     20820
     tgattaaaaa ctcaaatgca gtttctgagg aagatactca accgttccaa tgcaggttct     20880
     ttatctggga ctcagattgg agagcaaatt caaaggactg aaaatttgta atgactagca     20940
     taacttgctc ttaatcaatt ctcaattttg atgtgtataa accgcaaaaa gcattgagca     21000
     gtgcatcaca catctttcat taacattctt aatatgtata tacggaattt tgtacggtta     21060
     agatttcttt ttttgagatc cgagcatcat ttccaaacat ataactttgt ttggatgtac     21120
     ttttcttctg cacaccggac atttttgtgt ggcagccgtt gtacctaaag cacttagtat     21180
     acaaaaattg caaaatatat gcccacaggg agtacaagat aggttttccg gactatccag     21240
     acaaattaca cacttataat cagctagtcg ttgtgaagat ggaacaacct gttttttgct     21300
     aggttcttct ttttcaattt cggcgttggt ggtcgatggg ttctttccct gttcaaattt     21360
     ttgttttctt ggatcatagg aagtctcatc agttaaatca atcatatcgc ttatagtagt     21420
     aggttgcgcg tgaatactat taacatttgt taaactgttt tcaacggaag ctggatgatt     21480
     gttgtaggtg aatctttgat ttatgtcatc agcatcattc tgaaaattaa tgtcttccaa     21540
     gtcgaatact tcactttcca catctatgtt taaatcagag gtttcaacag gtagtgtttc     21600
     ttcttgtgct agctccgaag caacctctct tagcgacctt ggtgcacgat tcagtggtaa     21660
     agactcattc tcagaggtag tgcctgaagg atagtctgtt gcatcttctg aaaccggaaa     21720
     tccgtttcct ggcgaattct ctactggaga agaacgtctc ctatttattg ctgcatttcc     21780
     agctgcgact ctagcggatt gagatgggat attgtatggt gcagataagt ttctaacgtt     21840
     ggtatctctc ttatgtgcgg gtggcatttt tttgccaatt ggtcctgaaa ttcgaaaata     21900
     gtttatagat tattgattaa tgggctaata ttaggataat tttgatcgta tcctaatcga     21960
     ttgtcaaatg cttttcaggc ttgctagaat aataaaagag aattgtgtta acgtcaatat     22020
     acgcaaacag caattatttt ggcaacttgc caacaagttt aaaattaaat ttagtagacc     22080
     tatgattttt gaagtctaca tggaaaaatt ggctcactac cacaatgttg taagatgcta     22140
     gtctaattaa tatttatgac ctttttcatg agcacattca atagcgcaag cggtatttca     22200
     aataagaaaa gagaacagaa aagctggtaa aacttaattg tgtatcaata atcttttcaa     22260
     tgcagttcat taaactgcgc aaccgacatt attatgagta ttccataaac tatgcaaaaa     22320
     tgtattatgg agtgcattaa ggaatgctaa aataaaaaaa cgataacaat gtatatcgct     22380
     atttcttttc caaattgttg aatattagag gagtgtatat acttagcatc aaccaacgcc     22440
     ttttttttaa tctaggtctg ggtagacgca atggtcaaaa gctatacgcg gtacgaacca     22500
     accgaatttt ttggtgtcat tgcgtcttcg ggatgtaata ttctcggtca accctcttcg     22560
     tctgctaaat ctgtaggcag agccattgtt ggcggtcttg agtctgtttt ggaatgggat     22620
     ttaaagactg ggcaattact atcaaaatgg aaggattctg attgttcggc aaaagttact     22680
     tgtattgcaa actttgatga aatgtacgct gtgggctatg cagatggttc tatacgtctt     22740
     tggaaagatg gagagctctt aataactctt aatggtcata aaagtgctgt tactaccatg     22800
     gattttgata aaatgggcac aagattggcc agtggaagca tggataccga cattattgta     22860
     tgggatattg tagctgaaac cggcttgttt agactacgtg gacacaagga ccaaattacc     22920
     aagcttttgt tcattacacc tccttcgaag aatacagctg aagaaacagt ggtggacaca     22980
     gatattgatt ccggcgacat ggacgttgac agtaaatcgt ctgattcgtt tcttttgtct     23040
     gttggcaaag attcttttat gaagctttgg gatttgtcta ttcagcattg cgttgagact     23100
     catgtcgacc accaaggcga aatttgggct atgtgtgttt caccagacgc caaacggtgc     23160
     ctcactgctg gtaccggttc tgatgttaaa gtttgggaaa tcagttttcc agatgacaat     23220
     aatttcactc caactactaa agcatttcag caattaggta cctttacccg tcaaagccgt     23280
     gaccgtccca tcaccttggc ttacgacgtt tcaaaccgtt atgttgtatt ccaagctcat     23340
     gaccgtcttc tggaggtttt tcgccttcga tcaagtgcgg agctcgaaaa gattctgaat     23400
     cgacgacgcc gtcgtaaaaa gtctgaggac gtttcgatca cgttaaaaga cgaatatgaa     23460
     ccttttgctc taattcgaac cactgctcgt gcttcgtctg tagcttggat accaggaaat     23520
     cgtacaccta cgttggtaac atctcttcaa aataactcaa ttgaagttta cgctttggat     23580
     gtcaaatctg aaggttctgc tgcaccatta actgaacggg cttcgcgtat aagtgccatt     23640
     gaaattcctg gtcatcgtgc tgacgttcgt accttggctt tgtccgctaa tcacgatgtg     23700
     attttaagcg gtgctaacgg ctctttgaag ctttggaaca agaaaaccac atcttgtatc     23760
     cgtacaatcg aatgtggtta tgtacttgct gctagcttta taaataacga caagtgtatc     23820
     gtatccgctt acaaatcagg agaacttgaa gtctatgaca ttgctagctc ttctcttatc     23880
     gaacgtatcc aagctcacga tggcgcgatt tgggatttag cggttggtca cgatggcact     23940
     tacttcgcga ctgcctctgc cgatcacaca gtcaaactct ggtctctaaa atcgtctttt     24000
     gatttcgtac caggtaccac tagaaaagtc accacgttga aattagagca aacacgacaa     24060
     atagatttca cagacgatgt ccttgcggtt aaaatttcac ctgatggtcg tttcgttgct     24120
     gcttcactat tagataatac cgtcaaggta tactatttgg attcgttgaa attcttttta     24180
     aatctttatg gtcataagct tccagttctc tctatggata tttcttatga ctcaaagttg     24240
     ctggttactt gcagtgccga caagaatgtc aaaatatggg gtcttgattt tggcgattgc     24300
     cacaagtcta tatttgcaca tcaagattct attatggaag tcacatttca accagatact     24360
     tacaactttt ttacttgttc aaaagatcga gaagttcgtt attgggacgg taaatcattt     24420
     gatctaattt taaaacttcg cggtcatcac tctgaagtct gggcattagc tgttggtcca     24480
     acttttgttg tttctggctc ccatgaccat tcaatacgtt tatgggaaca aggtgacgat     24540
     ttggtatttc tagaagaaga acgggaacgt gagcttgagg agcaatatga gtcaacgctt     24600
     gtttcatctt atgaaaatgc tgaagccgac ggagaggtta aagacggaga cgtggcagct     24660
     gtcacgaagc aaacaattga aagcttaaaa gacggagaaa agatcttaga agctattaca     24720
     ataggtatag aggatttgga tcaagaaatt cagtacagac ttgatctgct taagagccct     24780
     ggtaaagccc gtggaccgag aaatccgata ttagcccatt taggtgtttc agctgaggag     24840
     tacgttttga atactttcaa aaaaattcgt agtagccact tagatgacgc tcttctcgtg     24900
     cttccttttg agcacgtctt atcccttttt cgatttattg atatttgggc tagtagaaaa     24960
     tggtcaattc ctctcgtttc tcgtataatc ttttttttac tcagaacgta tcaccgacag     25020
     ttgacaacta cagttaaaat gcgtccatta ctaaacaata ttcgtagtag tttgaggggg     25080
     tcactacagg aggagcgttc tctcatcggc tacaatgctg ctggtctttc ttatttaaga     25140
     catgaatggg agcttactca taatacttca ttagaagata ttgatagtac ttccttagaa     25200
     gtggatggaa agaaacgagc cttttccaac attgtttaaa gttcttaatc cttgggtaaa     25260
     aatatttgga tagagaagtt tattttgtat taaattggga tttttggtgg taaataaaaa     25320
     tgttttatta taatatttga aatatgcttt taatgctaga agaattctat taaaactcat     25380
     ttccttttac gaagtaagta acgtaactaa ttgaatataa tcaactttaa ttcataaagt     25440
     aaaattggac tgaaaaaact tttcaatgat caacgaaacg gaatagaagc aacatttatg     25500
     gcatatttcc tagtaattaa cgatatcaca gtaaatgacg cataaaacca ataaattatt     25560
     taatcggaga tgatgaacga tgaagtgaga ggtaaaagat aaacagattt aatcaaactt     25620
     tccactgttt ccagtgcttc tcatagaaac aggaaggatt ggggtggaat gtctacgacg     25680
     ttgaagagtt ctagctcttc ttccgctaaa gtaccacact aatattccaa cggtaacaat     25740
     ccccaagacc atatacagaa cacgaatatt caatccatat gattccaaat attcgacacc     25800
     aagattcttc tttagaattt taaatttcaa atggtcggga tcggtttcaa cctgcttaat     25860
     aatgtcaaat acagtatcct tttcaataga aataggagtt cccttagcgg tttcatccca     25920
     ataaatatct tgagcagcat tatacacaat cacacgtggc ccagttgctt caatatcaat     25980
     gtcaaactta cgcaaccact gagcccagaa tttaccattc acccatgcaa atctagtagg     26040
     agatggcttg ccatttacat gaaaattctt tgcagcttct attgcctcta agtcattttt     26100
     ctcttcagcc tcgtttacta aagagttctt tttgtcagtt tctttttgcc agtttgactg     26160
     gtaagtacgg ccttcttcat ctaaaaattc ggtagcaatc ttttgagcag tacgcttagt     26220
     ttcatcaaag tcatctaact caggatttaa caagaacagc acgacacttt catcgttgaa     26280
     aatttctttg gaattggatg tacgaagttc aggaagaaca ggaagccaat tgtttttcat     26340
     ccaaccaagt attcttctat agtccttgtt gtcctgtgcc attttagccg gataataact     26400
     agctatgcca tcacgaacaa caatgagctt ggggaaggaa acaacgcgat atttcttggc     26460
     aatttgctgt gaggtagtaa gatacaagtt agcatgtcct aaaagctgga ttccagtttt     26520
     acgaatgata ttcaaatatt cggcactatc gtcatcgtaa aagtacaaga aaaagacatc     26580
     accgttcttt tcggcgttaa cagtatccag tagttctacc tcgcgaatct caaagtttgc     26640
     agcttcctct gcaaagctaa ctaaatcacc ctcattggga agtccgacat actccacaaa     26700
     agcttcttcc ttaaagaaaa ggaatgttgg gaagtattga atactgtatt gcttgcaagc     26760
     acgttttgaa acagcacagt taatatgtgc gacattaagt ttaccacgca tacggttagc     26820
     catggcatac caagcagtgg agacgtcgtc gcaatcatcg cattcggaag aataaaattg     26880
     gataaaccaa ccttccttat cggtcaacgc agcatcaata tcagcatcaa gtgctagggc     26940
     tttggaagta cctgttgggt tgatggactt tttcgattcc tcagtttctt cagtgttttc     27000
     cttttcttcc ttctccttag gaaagcttgg agcggtctgg atcgaaaatt cagcgtcctg     27060
     aaccttggaa gctgcggatt tgggatctac ggaggcggat acggaggtga caggaagaga     27120
     ggaggtagaa gcaaccttag atacgctgct gagggtggct ttttttgatg ccacagaagt     27180
     aggagaagat gtaagctttt tggaagcctt agtaacgctc gagccactaa attcagaagc     27240
     agatgcactt ttggacatgg cagtagaagc taatgaaaga gaagagacgg aagtggagag     27300
     agcgggttgg atagaggcga cttcttctgt atcttcgtct gtcaacacat cctcatcgga     27360
     tgggatatca ggatcagtat cagggttcaa atgggtctct acaaagtcta ataaagaagc     27420
     ctcgctggtg gaagcgccaa aaggaacttc ttcgacgatt tcaccattct gatatagata     27480
     gagagtggga acagcacgaa tattcgcgca agaagaaagc tctttggagc aatcaacttc     27540
     accaaagtga aagttagagc cttcaacttg ttcttttgcc ttctcaacca tgttatccca     27600
     cattgggccc aatcttttac aggcaccaca gcttggcaaa taatacttta taaaccaagt     27660
     tcccttcgag acttccgact ccaaatcatt gtcagtaagt ggaactcccg aaacgagggt     27720
     ttgaaccatc gttataaagg ctacaaccca cgaaatacgc attacagaac caaaggtgtt     27780
     tgaccgcatt gtttgatgta aaaagccaaa cttcacgttt ctactgtatt gtatatctat     27840
     aacttttaaa taagtgaact tgtatcacta caagattgtt aaagaatttt cttcttcagt     27900
     gagttcgtgt taacgtaata tttggttctt ggtaaggtaa gcacatgctc tttgttacta     27960
     aatgaatgaa atcaatgcgg cgaaatacct taatattaca ataaatacgt ggtattatta     28020
     taaaatataa taccataaaa ataactatat taagaaactt gatataagaa tgtagaaaat     28080
     actctttgtc tgaaatttct ttttttaatg aaatgagttg aaagacgcac ggaataaaat     28140
     tttttaattt acagtaaaga tgtactaaat ttaagaaatt catcggaaaa accagcacca     28200
     tcgagtcgag gacgaaaatc ttaaggaacc aggaattatc acgaacacca actacaaaac     28260
     aataagctta atgggaatgc accaatattc actttgaagt atttactgct aataatatgt     28320
     tgatttgaat gttgctaact tgcattcata ttacttctcg ttgcggtcat tagtacatca     28380
     caaaattgtt agcgtattca agctcacttc agctgaagcg aacctcgctt atacattctt     28440
     ttgtaattcg ataagacttt ttaaaagtcc gtctatgaaa gttgcattca aaccatacag     28500
     tcgctaacgc tatactgata ttacctacat cctttaaaat acaaatccaa ccactaactc     28560
     atcacaaaca tccaacccat ctagttacca tgtaaatcca cctacctact gaattttcga     28620
     tacaaaaagt aaaaggtgaa ttaagcaaat gcttattggc caatacctga agaatttcaa     28680
     ttaaagacaa agggcccact cgctaaagtg aaaaagatca aagaaaaaaa acgaataaat     28740
     aaatttaagg aaatcaataa aagacaaacg tgagagcaat aatcatcata ataaaatgaa     28800
     cttcacgagg aacatgcatg aatgcgaaca ggaaggaaaa catgtaccga ttatataaat     28860
     aagtcgtttc gtaattaaaa agtaatcatc tagtaaacgt cctccaataa actaataagg     28920
     aggacaaagg gagcaaatta tttataaaga agaatggctt cctcgctcca ttcccacctc     28980
     ccttttaacc gcagcaggct ccaagagctg cattggcgac agaggcacca atggccgcac     29040
     cgaagccgaa cacgacggca ttccacattc tagaaaaaaa gtttccagtg ctcattttaa     29100
     tccttcgact ctgttgtttc tcctgaaacg tctgggccat cctgtatacc taagagaggg     29160
     agagtaaaaa aatatatatt aacaaacaga aaacagggtt tttagtaatt gaacacgcaa     29220
     gaaaaccaag gatatgctag tcctaatcga attgctcgtt cgttgatcaa tataaaaaga     29280
     aggttgattc aacggggtcc acaattaagg tagttcttag cgaacaagaa aattaaccaa     29340
     aaattggtct tatgaataat taaaggaatt ggatttatga aaagctacta caaagctgtt     29400
     ccgcaatgag ttataatgct gcctacttaa gatctaagga taaaggcagt aggtaagtgt     29460
     acagagaagt ggaaatctct ctctttttat atatatgtgg gtgtaaatac gtgtgggggg     29520
     aaggctgaac tactacacgt cacacaatag ggaaattcgt caataaatga cgcagctgcg     29580
     aatccctgtt tatttacgct tgcgaaaaga cggaaaaaat tttattcaaa ttctaacaag     29640
     aatgtagtaa acaatgatta ggtggtgcaa cgatttacac taaaccactt tcaaatcaaa     29700
     gcgttaagtg attgtgaacg tataaataaa aaatgggatg gattgaattt ggattatatg     29760
     tttaaataat taagtggaat ttaactaaaa agtacaacaa caatatcatg agacgatcta     29820
     actgtcaaga aaagaaaagg aacattttta atgattcggt aacaacccaa attcttctat     29880
     aaaaaaacag gacttttaac agcagccttt tcttttcgtt ttatccttgt tttcttagct     29940
     tcgtcttcaa gttaaggtcc tcaatgggcc attgatgaat agtaaatcaa aagaaaggag     30000
     ggaataaagg ggggagctgc atataaacca cagcgtatca caacacaatg aatgaatggt     30060
     gagatggcac gcatttgcat aattgacact gagactgaca tttgaagtgc aaattacgct     30120
     tgcatacgac tttggatact ttatgcttat aacttgttgg ttaatagtcg tccgttaaac     30180
     ttttctcttt ctctgtcaat ttttttcctc ttgtttcctt atttcctgtt cccttctccc     30240
     taatggtttt ggaagagtaa aagaaatagg aaactagaaa aaccaaagac gtacttgact     30300
     tgttgaaact tataaaggaa aataataacc gcaagtatct cccgtgctaa gatcaagttg     30360
     gtgttacaca atattataca aaaaagaacc atcatttaat ttatccatac attgcataaa     30420
     tgaacctgac acaccaagca cacgtgtata taacaggtaa gcaaacggta tatatatacg     30480
     atacatagat atccaataca tatacacctg tccactaaat agcatgaaaa agggacaaca     30540
     aaaacaaaaa aagaacaaga gaaaggataa aaaaagaaga taaagaaagg agaagtaaat     30600
     aaaaataaag taaaaagaaa aaaaccataa cgtgcacaaa ttaggtagcg ccaagatcta     30660
     aacaaattaa gatgtagacc aggtgaaaag tggttttgtg aagatcaaac accaatcgac     30720
     caggaaaata aagaaaagag aaaacttagc gtgttcatca tattgagaaa gggtagacaa     30780
     atgtacaaaa gatcgctact agacaatagc gtcaaagaca caaaaacaac caattagata     30840
     acaacaaaaa gaagtaagac aacgagaaaa gaaaaggaaa aaaataaaga aagaaataaa     30900
     accagttttg ccaaaacaac tattgcatag gagtttagcc tttccaaatt atcttattaa     30960
     atttaaaaaa aaaatcaagg tttagccgat aaatcaagcc aactttgctt tctttcccaa     31020
     gtcccaattt catcaattca taattgacgg ttatagaaaa taaagataaa gcgaaaatga     31080
     ataagaaaaa aatatgaaac tgatttgtca ctaacactgc aacggtttaa cacatattga     31140
     aaacaaatcc agtttcccga aagaaagata aagagaagaa gaaaaagtaa agaacgaata     31200
     aaataaggga aaataaataa ataagattat gccaacagag aaccgaccat aaagaacttt     31260
     ttatcgttac caaaatgatc acttttccga tcatatgcaa aagatttgta gcatacgatt     31320
     atgaaagtca taaacaccat aaagaagaaa taattttttg gttgaattta aataaagtaa     31380
     aaaagaaaaa tgttgtttta gttcaaattt gtgacacgca atatctttct cgaataatcc     31440
     tgactgtcag ccaaagattc acttgatttg cgattcatca tggcaggatc caagcgagaa     31500
     tctaattcac tagcatagga gggatatttt ccttcatttg ccgagtcgct cattctaatt     31560
     ttgaatctcc tgaaatagaa gtataggaaa atgcacaatg ccattaccac ggcgaatgcc     31620
     acacaaccga taacaatacc cacaatagca cctgcattca aggacgtatg gtttgacgcc     31680
     ttgcttgcat ttagagcgag ggcagccgta ctgcttggaa cttcactact ggttgaagaa     31740
     gaggaactgc ttggtgttac tgtgacagta gaaataaaag tagatgagga catggtcgtg     31800
     ataaacgacg aagacgaaga tggccgacta gaagatgaag aggaagatga gcttgaagat     31860
     gaagaagaat gagaagaact ggtggaagac gttattggta cggaagagga agaactagaa     31920
     gacgaagagc tggaagaaga cgaagaagac gaagacgaag aggaagagga agaggaagag     31980
     gaagatgagg aagaagaaga agaagaagac gaagaagaag aggaagacga cgaagacgaa     32040
     gaagaagaag aagaagaagg agatgttgtt gttgtagttg aagatgagct tggagatgat     32100
     gatgaagacg aagaggtcgt agacgacact gacgagctag aaaccgtggt ttgcaaaacc     32160
     ccattgccag tcagataaac cgaccagtac agatcaccac cacacataag agaaccataa     32220
     cctggacaag gcgttgtgca aagagaactt gaaacttctg tagcagtaag tgtactaccg     32280
     caataacatt gattattacg gatagctaca aatgctatat tatcagatc                 32329
//