ID SPBC359 standard; DNA; FUN; 26000 BP. XX AC AL356012; XX SV AL356012.1 XX DT 13-MAY-2000 (Rel. 63, Created) DT 13-MAR-2002 (Rel. 71, Last updated, Version 3) XX DE Schizosaccharomyces pombe cosmid c359. XX KW adducins; alanine racemase; amino acid permease; atp-dependent permease; KW ser/thr-rich protein. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-26000 RA McCombie W.R.; RT "Sequence analysis of a region of the fission yeast genome"; RL Unpublished. XX RN [2] RP 1-26000 RA McCombie W.R., Lyne M.H., Barrell B.G., Rajandream M.A.; RT ; RL Submitted (11-APR-2000) to the EMBL/GenBank/DDBJ databases. RL W. Richard McCombie, Cold Spring Harbor Lab, 1 Bungtown Rd, P.O. Box 100, RL Cold Spring Harbor, NY 11754, USA and Sanger Centre, Wellcome Trust Genome RL Campus, Hinxton, Cambridge CB10 1SA XX DR GOA; Q9P5N0; Q9P5N0. DR GOA; Q9P5N2; Q9P5N2. DR GOA; Q9P5N3; Q9P5N3. DR GOA; Q9P5N4; Q9P5N4. DR SPTREMBL; Q9P5M9; Q9P5M9. DR SPTREMBL; Q9P5N0; Q9P5N0. DR SPTREMBL; Q9P5N1; Q9P5N1. DR SPTREMBL; Q9P5N4; Q9P5N4. DR SWISS-PROT; Q9P5N2; YH83_SCHPO. DR SWISS-PROT; Q9P5N3; ALR2_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC CDS are numbered using the following system eg SPAC5H10.01c. CC SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid SPBC359 is overlapped at its 3' end by cosmid SPBC1683. XX FH Key Location/Qualifiers FH FT source 1..26000 FT /chromosome="II" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /clone="cosmids 359 (partial), 1198 and 1683" FT /clone_lib="Mizukami, et al., 1993. Cell 73:121-132." FT /map="IIL" FT CDS <1..1296 FT /codon_start=1 FT /db_xref="GOA:Q9P5N4" FT /db_xref="SPTREMBL:Q9P5N4" FT /note="SPBC359.01, len:431, SIMILARITY:Schizosaccharomyces FT pombe, CAB63555, amino-acid permease, (423 aa), fasta FT scores: opt: 2407, E():0, (84.2% identity in 424 aa)" FT /gene="SPBC359.01" FT /gene="SPBPB10D8.08" FT /product="putative amino acid permease" FT /protein_id="CAB91570.1" FT /translation="DPAWGFAVSWNYFLNYFVTCPLELTTCAITFKFWTEINSAAWISI FT FLAVVIVINLFGVRAYGEVEFILSTIKVIATVGFIILAIIINCGGVPTDHRGYIGGSII FT KQKPFRHGFKGFCSVFTTAAFSFSGTEIIGLAAAEVGNPRKSVPSAVKQVFWRIAIFYV FT VSLILIGLLVSPDDPRLMGNGDVSVSPFVLAIQEANIKGLPSVFNAVIIISVVSVTNST FT TYTAARTLQGMATLKQAPKFFSYTDRVGRPLIAMVVVLLFGFFAYINEADKNGSDISDT FT VFDWLLAISGLSSFFTWGSICLSHIMFRLAFKKQGHSLKELGFVSPMGIWGSVIGLGFN FT ILCLMAEFYVSLFLIGGSPNANDFFQGYLAACIALAFFIGYKIYDRSHIPSLDKLDIDT FT GLKTYDNQDEEKEEYSSKGPLNILKKAWNAVC" FT CDS 2182..3294 FT /db_xref="GOA:Q9P5N3" FT /db_xref="SWISS-PROT:Q9P5N3" FT /note="SPBC359.02, len:370, SIMILARITY:Schizosaccharomyces FT pombe, O59828, putative alanine racemase., (375 aa), fasta FT scores: opt: 1629, E():0, (62.5% identity in 376 aa)" FT /gene="SPBC359.02" FT /product="putative alanine racemase; no apparent S. FT cerevisiae ortholog" FT /protein_id="CAB91571.1" FT /translation="MRGARAVIDLRAIGYNYNLIRELLDEKNPDAHILCILKANAYGHG FT AVEVAQFLAKYCSAEGFGVASIEEALELRLSGIQNRILLLEGFFTDEDELSLIDKYNFS FT ITIHCEEQLKSFMNYPFKKPVEVHLKLDSGMNRLGFTPAEYADKYRLLKNHKNVSGIVK FT ATHFAFADIPEKSEYTLKQWRIFEKAAGCLPDPLSAGGGVIVVGWLNTIHMDWLRTGSM FT LYGLDPYDLDAKAPELPKPLIPAMKLMSTIVCVKHVEKDQPIGYGGAYVTTRDSLIGVV FT AIGYGDGFPQVRNGCPVIINGKRVPTVGKVCMDMLAIDVTDVPDVKRGDDVVLWGNPEL FT TIEEVSTFSNENPFEIITGLTRRVPLQYTF" FT CDS complement(5732..7471) FT /db_xref="GOA:Q9P5N2" FT /db_xref="SWISS-PROT:Q9P5N2" FT /note="SPBC359.03c, len:579, SIMILARITY:Schizosaccharomyces FT pombe, CAB60021, amino-acid permease, (537 aa), fasta FT scores: opt: 2901, E():0, (81.0% identity in 531 aa)" FT /gene="SPBC359.03c" FT /product="putative amino acid permease" FT /protein_id="CAB91572.1" FT /translation="MSAKDYDFDIESVLPEEKAPQVSEAKKDYISQESTVLSGQVDFVE FT PEHKGFFQNLIDGFKPAREADGNGGPALKRGLSTRHMQLMSIGGAIGSGLYVGSGSALA FT DGGPASVIINYILIGIMMFFVIYALGEMAVAYPVAGSFNTYATRFIDPAWGFAVSWNYF FT FNYFVTFPFELTTCAITFTFWTDVNCAVWISIFLVVVIGINLFGVRVFGEVEFVLALIK FT VVATVGFIILAIIINCGGVPTDHRGYIGGSIIKQKPFRHGFKGFCSVYTTAAFSFSGTE FT IVGLAAAEVGDPRKTLPGAVKQVFWRVAIFYIVSLILIGLLISPDDPKLMGNGSASVSP FT FVLAIQEANIKGLPSVFNAVIIISVISVTNSSTYTAGRTLHGMANLKQAPAFFKYTDRL FT GRPLIAMIVVLSFGFFAYINEANNNGNDISDTVFDWLLAISGLSNFFTWGSICLSHIMF FT RLAFKKQGHSLKELGFVSPMGIWGSVIGLGFNILCLMAEFYVSLFPIGGSPNANDFFQG FT YLAACITLVFFIGYKIYDRSHIPSLDKLDITTGLKTYEYEETKDSSDTGRFRFFKKIIN FT TVC" FT CDS complement(12675..13751) FT /db_xref="SPTREMBL:Q9P5N1" FT /note="SPBC359.04c, len:358, SIMILARITY:Schizosaccharomyces FT pombe, YAH2_SCHPO, hypothetical 62.9 kD protein c8a4.02c in FT chromosome i., (609 aa), fasta scores: opt: 323, FT E():6.7e-10, (28.6% identity in 315 aa)" FT /gene="SPBC359.04c" FT /product="serine/threonine-rich protein; low similarity to FT cell surface proteins; predicted N-terminal signal FT sequence; similar to SPAC186.01, SPBC947.04; possibly S. FT pombe specific" FT /protein_id="CAB91573.1" FT /translation="MNSLKSLCLKCIVTLCLLVNAFAFDYASLQEQDENLLAACPQYIT FT IYTNGPVPGTTTIYPTSNVASNTSENYPYTGSKSLSSSSILSNSTISTSSSTPITASVP FT TSSSILSNSTIPTTSPVPTTSSTPTSSSILSNSTIPSSSSISASTITTTIISGSTQFTT FT TFVDQSIDTVEVVIPTAGYITTTLTSGSSYPVSTTTLQTVSGTQSGLVEVITPSCGCNP FT ENSFHLRLVGDSINPSYVYKNTNVSDPDEGNMYTSTEGNTEAVNVFYYDPTVERILTCD FT CVRPVYTIYTDDPDSSFDIIKNNNGTFTFVESSSGEIQTLHVSQYGALWITSPEYDGET FT GGMDDVGFRADDVILVAY" FT CDS 17170..21567 FT /db_xref="GOA:Q9P5N0" FT /db_xref="SPTREMBL:Q9P5N0" FT /note="SPBC359.05, len:1465, SIMILARITY:Schizosaccharomyces FT pombe, YAWB_SCHPO, putative ATP-dependent permease FT c3f10.11c., (1478 aa), fasta scores: opt: 6358, E():0, FT (63.3% identity in 1472 aa)" FT /gene="SPBC359.05" FT /product="putative ABC multidrug or ion efflux transporter" FT /protein_id="CAB91574.1" FT /translation="MITANKGLSLVLLIPNLFALVSGGLQYVFDVRRRIFRPHFSQFWT FT IWMKFFSIALVIITQIYVGYKTKNIGWNFFSVVTYCFVLFLQFAEQSTLRVPMASLLIF FT WLLKVVTSLLILLFSPYIAITSMARLLTLITLFCSLVCFISEVYVPPCNRVWYSDDTNE FT VEEKGIRPSEVRYANIFSKLSFSWISSFIKFGYTNYLKESDVWLLPPDERSGNLIIGFE FT DWWIYHSKNKRRSLFLWKLLFFNHWKLVALITITKLIQDVLAFVQPTLIQKTILFISSY FT TSPNPESPSRGFIIAILVLVANFLQTLLLQQYNQLIMLLGMRWKTELLASIYRKSLLLS FT SSARQNRSIGDIINYMAVDTQKISDLPIYLFIIVSGPFQIALALSNLYHLMGYSAFTGV FT AASVILFPCNIIVANVYKKFQSILMKNKDSRSKLMTEIINNIRSIKLYAWETPFLQKLL FT HIRNTKELSMLKKIGFITAIGDFAWIFTTIIVTTVAFGAFIIFHGKTQALTADIVFPAV FT SLFNLLQFPLAMLPTVISSLLEASVSVSRIYEFLIAQELDYNGVQRFPATEIPHEICLE FT IKSGTFSWSKKTLKQQVTPTLRQINFVAKNGELTCIFGKVGAGKSSLLEACMGNMYKNS FT GSVFQCGSLAYAAQQPWIFDATIRENILFGSEFDPELYEKTIHACCLKRDFEIFTEGDQ FT TEVGQKGASLSGGQKSRISLARAIYSQADIYLLDDVLSSVDQHVSRDLIKNLFGPEGFL FT RTHCVVLTTNSLNVLKEADSIYILSNGKIVEKGNYEHLFVSTNSELKQQLSEFNDEKDT FT QPLPEHTTSYPSTQISLAPSIHVEGLETYSSSERKDSSNKYKSRKRNPIRQKVTEDDKG FT KCVAQTDELVQRGKVKWHVYWMYFKSCSIGLILLYFFFIISGIMMNVATNVWLKHWSEE FT NGKSSSELNPSPYFYLGIYLFFGFLSCAFISSSSLTMTVLCGIRSGRYLHDSMLKTILR FT APMGFFETTSSGRILNRFSNDVYKVDEVVSLTFMFFFRNSIQVLFILGVICYSAPLSLL FT LIVPLFFLYLYNRAYYVRTSRELKRLDNVTRSPLYAHVQESLSGLSTIRAYGMQETFVE FT ENDLRIDTNHRVWFMFFSSSRWQAIRVECIGDLIIFCTAFYGILSAIKGSPNPGLVGFS FT LSYAIQITQGLSFIVQQSVDAENNTVSVERILEYINVKSEAPEIIPENRPPCEWPTDGA FT VSFNHYSAKYREDLSFALNNINIEISPREKIGIVGRTGAGKSTLAMALFRIIEPTEGKI FT EIDNEDITKFGLYDLRSRLSIIPQESQIFEGNIRENLDPNHRLTDKKIWEVLEIASLKN FT CISQLEDGLYSRVAEGGANFSSGQRQLICLARVLLTSTRILLLDEATASVHAETDAIVQ FT QTIRKRFKDRTILTVAHRINTVMDSDRILVLDHGKVVEFDATKKLLENKDSMFYSLAKE FT SGLI" FT misc_feature 17917..18750 FT /note="Match to PF00664 ABC_membrane, ABC transporter FT transmembrane region. Score 181.94" FT misc_feature 18988..19509 FT /note="Match to PF00005 ABC_tran, ABC transporter Score FT 75.02" FT misc_feature 19876..20700 FT /note="Match to PF00664 ABC_membrane, ABC transporter FT transmembrane region. Score 211.68" FT misc_feature 20926..21477 FT /note="Match to PF00005 ABC_tran, ABC transporter Score FT 182.38" FT CDS 23248..24021 FT /db_xref="SPTREMBL:Q9P5M9" FT /note="SPBC359.06, len:257, LOW SIMILARITY:Homo sapiens, FT Q13734, alpha-adducin., (662 aa), fasta scores: opt: 336, FT E():4.3e-15, (29.4% identity in 235 aa)" FT /gene="SPBC359.06" FT /product="putative class II aldolase and adducin N terminal FT domain; no apparent S. cerevisiae ortholog" FT /protein_id="CAB91575.1" FT /translation="MAKVTGLPEFEDLHTKRKWMLNHMAAAFRMFGRNGYNEGTAGHVT FT VRDPIDENTFWINPLEVPFSLMKPSDLVHINSDGEIIGGSKMKYNTSGFAIHYEMHKVR FT PEVICVCHVHSIYGKAFSALGKPLDMLNTDCCVFYNNHGIYFDMDDVISMPEEGRRTAK FT GLADYKAVLVQNHGIMTVGTTVDEAAYLLSLMERSCQIQLLIDSATKVGERKHVHPTRA FT KAIRENADNPVGLYTAQQPNFLYEVACSNGELEII" FT misc_feature 23299..23910 FT /note="Match to PF00596 Aldolase_II, Class II Aldolase and FT Adducin N-terminal domain. Score 64.68" FT misc_feature 25501..26000 FT /note="nominal overlap with cosmid SPBC1683" XX SQ Sequence 26000 BP; 8752 A; 4023 C; 4428 G; 8797 T; 0 other; gatcctgcct ggggatttgc tgttagctgg aattactttc ttaattattt tgtcacgtgt 60 ccattggaac taacaacgtg tgccattact tttaaatttt ggacagaaat taatagtgca 120 gcgtggatta gcattttttt agcggttgtt attgtcatca atctttttgg agttcgtgca 180 tacggagaag tggaatttat attgagtact attaaagtaa ttgctaccgt tggtttcatt 240 attttagcca tcattattaa ctgtggaggt gtaccaaccg accatcgagg atatattggt 300 ggcagtatta tcaaacaaaa accatttcga catggattca aaggattttg ttcagttttt 360 accactgctg ctttctcctt ttctggaact gaaattattg gactggcagc agccgaagtt 420 ggtaatccaa ggaaatccgt acccagtgct gttaaacaag tgttttggcg tattgctatc 480 ttttatgttg tctctttaat attgattgga ttgttggtca gtccggatga tcctagattg 540 atgggcaacg gcgatgtcag cgtttcacct tttgttctag ctattcaaga agctaatatt 600 aaaggtcttc cttctgtttt taacgctgtc attattattt cggtagtttc ggtaaccaat 660 tctactacgt acactgcagc tcgtaccctt caaggtatgg caactctcaa gcaagcaccc 720 aagttttttt cttatactga tcgagttggc cgtcctttaa tagccatggt tgtggttctc 780 ttatttggct tctttgcata cattaatgaa gccgacaaaa acggaagcga tatcagcgac 840 acagtgttcg actggttact agcaatctca ggattgtcaa gcttttttac ttggggaagt 900 atatgtttat ctcatattat gttccgttta gcatttaaga agcaaggtca ttccttaaag 960 gagttgggat ttgtgtctcc catgggaatc tggggttcag tcattggatt gggtttcaac 1020 atattatgtt tgatggctga gttttatgta tctctgttcc tcataggtgg tagtccgaat 1080 gctaatgatt tctttcaagg atatctagct gcctgcattg ctttagcttt ttttattggt 1140 tacaagattt acgacagatc gcatattccc tctttggata aactagatat cgatactgga 1200 cttaaaactt atgacaacca agatgaagaa aaagaagaat attcttccaa gggtcctcta 1260 aacattttga aaaaagcatg gaatgccgtt tgctgagcac attttacaag cacctgttaa 1320 tatgtatttc ttttcgtctt tttttacaat tgttttgtct ttgttgcata ccctttccct 1380 aactacatct tttcacgttt ttttgaattt caatacctga acaacttcgt tcctaatctt 1440 ctataataaa ccgggttgaa agatcttaat aaaaacataa cagttgctat ttggatttta 1500 cgtatctcat ttatcaaaag cacgtatttt aattttgatc gtaattttct ttaaatatac 1560 acacctttca taataaccat attataattg aatagaacag ttttgcatgc ctaggagggt 1620 gtcgaaataa ccagctaaag ccaatttctt gttcccttct gttttattag ttatttagat 1680 aatctgtagt aatagttatt caaacaaaat ggttgaagca ccaagttgaa tctttttaca 1740 aataatttta atttattata aagctgtggt tcaatagttg tttacatttt aattgccatt 1800 ttatttagtt aatgttggtt tttcatttaa cagtttgaac aaaaagtcca actatatccg 1860 catatctgcc tatcataatt gaaattttgg gaaatcattt cacatttgca atcaatttaa 1920 tgcacaattt gtcattctga tttcagcaac gctaatgcga atttatgatc accggacacc 1980 acggaggcac cacggactat aaagatgtaa tttccggttg catataaatt agcgtgaaat 2040 atgtgaaaat ttagataaat tgtttaaata aacagtaagg atttgaatta cttatagcat 2100 cgctttttcc accaacgaat ttgagaaaca aacagatcag ctagcttgca ttctaatcac 2160 aaaacaattt ctattttaac gatgaggggg gctagagctg ttatcgattt gcgcgctatt 2220 ggttacaatt acaatctcat tagagaatta ctagacgaaa aaaatccaga cgctcacatc 2280 ttatgcattt taaaggcaaa tgcttatgga catggagccg ttgaagttgc tcaattcctt 2340 gctaaatatt gttcagctga gggttttggc gtcgcatcca ttgaagaagc tctggagtta 2400 cggcttagcg gaatacaaaa tagaattctt ttgttggaag gcttttttac agatgaagac 2460 gaactaagcc tgattgataa atataatttt tctataacta ttcactgtga agaacagtta 2520 aaaagtttta tgaattatcc atttaaaaaa ccggttgaag ttcacttaaa acttgattct 2580 ggaatgaatc gacttggatt tactcctgca gaatatgctg ataaatatcg gttactaaaa 2640 aatcacaaaa atgttagtgg tattgtcaaa gccactcact ttgcattcgc ggatatccct 2700 gaaaagtccg aatacacatt aaaacaatgg agaatttttg aaaaagctgc cggctgctta 2760 cctgatccac ttagtgctgg aggtggagta attgtagtgg gttggttaaa tacaattcat 2820 atggattggt tacgcactgg ctctatgcta tacggacttg atccatatga tctcgacgct 2880 aaggctcctg aattacctaa accgttgatt ccggctatga agttaatgtc tactattgtt 2940 tgtgtaaagc acgttgaaaa agatcaacct attggttatg gtggtgcata tgtgacaact 3000 cgtgattcgc ttataggcgt tgttgctata ggctatggtg atggatttcc tcaagttaga 3060 aatggatgtc ccgtaataat aaatggaaag agagtaccaa cagtaggaaa agtttgtatg 3120 gatatgctgg ctattgacgt tacagacgtc ccggatgtta aaaggggtga tgatgttgtt 3180 ttgtggggga atccagaact gacaatagaa gaagtatcaa ctttttctaa cgaaaacccg 3240 tttgaaatca ttacaggact taccagacgt gtaccattac agtatacgtt ctaaaaatgt 3300 cgtttaaata ttaaatttat ttatccatta ttttaattct tgaattaaag agtggaaagc 3360 gttctttctc tttttcttct ttcttattac tatttaacaa aaatactttt ctttgattaa 3420 tttttttaaa tgcacaatta atcaaatgta ggtgtttaat ataagaagaa ttgatgaacg 3480 tctttatttt tactttttta taactattgg tttttgtata atagtgttaa aagtatcgct 3540 tgagcataaa atatgtgaaa gtgatcaatg attggtaatt ttttactatt tatgaacaaa 3600 ctttccacca gttaaaaccg catcctttga tctttaatca ttttgttttg tttttttttt 3660 taaagcaaaa gaagtctgtc gattatctaa aaaaaatgca tataaaatta aaaagacaat 3720 aaaaaaataa agattacagt tactgtttta atatttaaaa attgtggaca ataaaggaac 3780 agataaaaat aataattatc gatgctcgtt acaatgaatc gtagcctgag gagaataaga 3840 atgcattaaa atttattata agagaaacaa gaagacctat aatgttttca tatatcttgt 3900 tgtattttaa tacaacatgt atgtaattta acggcacttt agggtattaa attaaaaata 3960 acttttaatg gctgtttata tcgtgctcat cttgtgcgcc ttcgacctta atgattttct 4020 gtttgttata ttttactaaa tgcgtcctgc atgctcgctg ttagcaacat tctttataga 4080 ttttcgaatc ctgtcagttg tttacaagtg tttgagtcac tgaagtttat tattgcttga 4140 taatcatctg gctctatttt ctcaaatatt ttgaagttat aggtagtaaa ataaaaacta 4200 ttttttgttt attttaattc ggaaaaggca aaaaacacgt tgctttgcgt aaatgcccgt 4260 tatagtttct tcgagtacag atatgattct ttcaaatagg gatgatcaac gctaatggta 4320 aaatgcaaaa tgatatttag agctggatat ttttcaggca ataaattgcg atactacact 4380 atatgacgtt tattatgttt ctaaatctcg tttgtaatat aatatctgat cgccctgtac 4440 caaactgtct gataaaaatt tcagtaatgg aatcatcatc aactcgtaaa tacaatcctg 4500 aaggatttat tttgtttaaa taagtatatt ttaaatgacg gttttgatat accgaatttt 4560 ttggtttatt ttgaattccc tttagctttt gagtaatttt ttatatatct attattagtg 4620 atttttattt acgtcaaagt agtagattta ttcaaagcac atatgatact aaagaatttc 4680 agctttcaaa attatatgca tcacgctgtt tgaaacctaa aattttttaa tgtcatttta 4740 tctgtcgtac gtaaattatt tgcaagagtg tttaataaat ttcttgatag ttgctatttt 4800 aaataaaaat gctttatgta tcaagtcttt tgtatctgta tagatacttt gcttactgcc 4860 tattaattta tatgttaatc ttcttttgaa gtatttaaaa aatttttttt agcgagcacc 4920 ttaaaaataa tgaggaaaaa aacaaaggat atcttcgtat attgcaatta aaagagaatg 4980 tgtgtaatta ctgcacgttt ttgttttttt gtcaaaaaat atcataatca ttgttttgct 5040 aacgtttctt tacctctatg cccgcttaat tagtcaaatt ctccaaacat atatttcggc 5100 gctttcgact attagctgat tcctacctat tttcattctt ttactatttc atttaattaa 5160 tgtaggtcga attgtaaacg agtttcattt ccattggaca agatattcga ataaatgagc 5220 tgcttaatca tgttaattgc tgcaaaaaaa taaaaaaaaa taaaaaaaaa aataaaaaca 5280 gatcatttaa caagtagatg atcatgttat ccgatatgac taaataaaat tgacgactat 5340 ggtgcaaaac tgaatggtag catagcactt caatcaaata tctctattta ttactaatac 5400 tagatttaca atgagactta aatagaaact tttaattttg attagaaaaa ttacaaattt 5460 ttattttttg atacgttata ataaattaac tagattttcg ggcagctcga cattttataa 5520 gatccttatc ccccggactg catactgtat caagctattt ataacttcaa aagtaataag 5580 tttataaata aataggtata attatttgta aaaaaagggt taaaaagaaa taggctttat 5640 ggaaacctaa tttttgatga aaaatgcctg agatgatcca aactctgaaa tcgaagtaat 5700 atgcaactat taaaagctta aataattttt tttagcaaac ggtattaatt atttttttga 5760 aaaaacggaa tctcccggta tcagaagaat ctttcgtttc ttcatattca tatgttttta 5820 aaccagtggt gatatccagt ttatccaaag agggaatatg cgatctgtcg taaatcttgt 5880 aaccaatgaa gaaaacaaga gtaatgcagg cagctagata tccttgaaag aaatcattag 5940 cattcggact accacctatg gggaacagag atacataaaa ctcagccatc aaacataata 6000 tgttgaaacc caatccaatg actgaacccc agattcccat gggagacaca aatcccaact 6060 cctttaagga atgaccttgc ttcttaaatg ctaaacggaa cataatatga gataaacata 6120 tacttcccca agtgaagaag ttggaaagac cggaaattgc tagtaaccag tcgaacactg 6180 tgtcactgat atcgtttcca ttattattgg cttcattaat ataagcgaag aatccaaatg 6240 aaaggaccac aatcattgct attaaaggac gacccagacg gtcggtgtac ttgaaaaatg 6300 caggtgcctg ctttaaattc gccataccat ggagggtacg accagctgta tacgtacttg 6360 aatttgtcac ggatattacg gaaataataa taacagcgtt aaaaacagaa ggaagacctt 6420 taatgttagc ttcttgaata gcaagaacga aaggtgaaac gcttgctgat ccgttgccca 6480 ttaatttggg atcatcagga ctaatgagca atccgatcaa gattagggaa acaatataaa 6540 atatagctac tcgccagaag acttgcttca ctgcaccagg tagtgttttt cttggatcgc 6600 cgacttcagc cgctgccagt ccaacgattt cagttccaga aaaggagaaa gcagcagtgg 6660 tatacacaga acaaaatcct ttaaatccat gtcgaaatgg tttttgttta atgatactgc 6720 caccgatata tcctcggtgg tcggttggta cacctccaca gttaataata atggctaaaa 6780 taatgaaacc gacggtagcg accactttaa tcagagctaa tacaaactcc acttctccaa 6840 aaacacggac accgaaaagg ttaataccaa taacgacaac caaaaaaata ctaatccaaa 6900 ccgcacaatt gacatctgtc caaaacgtaa acgtaattgc gcaagtcgtt aactcaaatg 6960 ggaatgtaac aaaataatta aaaaaataat tccagctaac agcaaatccc caggcaggat 7020 caatgaagcg cgttgcataa gtattaaaac tgccggcaac tggatacgcg acagccatct 7080 cacccagagc ataaataacg aaaaacatca taataccaat taaaatataa ttaatgatca 7140 ctgaagctgg accaccgtcg gccaaagcgc ttcctgaacc aacatacaaa ccactaccaa 7200 tagcaccgcc aatagacatc aattgcatat gcctcgtact taaacctcgt tttaatgcgg 7260 gacctccatt accgtcagct tctctggctg gtttaaagcc atctattaag ttttgaaaaa 7320 accctttatg ctcaggttct acaaaatcaa cttggccaga caaaactgtc gattcttggg 7380 aaatataatc ctttttggcc tctgagactt gtggagcttt ttcttcaggc aaaacgcttt 7440 caatatcgaa gtcataatct ttagctgaca tcttgaaaat tacaagtagt acgggctaga 7500 ctgtttagtc aaatgattat tcacaaacac gaattgacag aaggaaaaga aaaaaaaaat 7560 acacaagttc gaaagattgc ttttaaagta aaaaggaaaa taaaacaaat atctcttgaa 7620 agcttatata tttaccaatt gaaaattggc aaatacaaaa agtaaaaaaa aaaaaaaaaa 7680 aacttcagat ttgttaggaa gtattgtcag agcaataaaa ataatgccca gcgatgataa 7740 aaatgtcgaa atactaatat aagctgcact caagtgttaa gtagtccgtc ggtaaatttg 7800 cagtggtcaa gtttatataa gtctgtttga atttttttta aacctcgtaa aatttttttc 7860 ttacgatagt gttattgcga aaacttttca agcgctgatc gcatttttaa aaatgtcaga 7920 tatgcttata tatagtagat ctcggtatca acgtcctaat cttcggtgat ataattttat 7980 tgaccgtaat ccgtggactt cgaaattaaa tgaagtttta ccgtgtacat cttgataaat 8040 taaagctagt aattaacaaa aagtcgataa gatggtccgc aattgttcta aagactttta 8100 gggaaagacc atgacgagcc ttaagataat gtataatgat agtatcctca aaaatagaat 8160 tctatgtcta tcaccttcaa tttattaact tttgatatat acttttaaag acagcaaaag 8220 ataaaggctc ctgaaaaaat ttttgtacac attccaattt accatcttaa ttgctaattt 8280 taaaaacgaa attaaagcaa attacataga aaatgaaaaa catcaatatc taaatttgga 8340 tgttaatgca agtttcaaaa agcagttaat caaataagtt acacaaaatg tgatttgcta 8400 gcaaaacagt aacataaaaa ttcccaaatt aacaattttg cacggtatca tgttaccgcg 8460 ggtagtgaaa aaaaattttt caagtgaaat ataggttaaa tttgtttact tcccaaaaat 8520 tttgaaaaaa aaaataataa ttgctttttg atgcattata aactattaaa gtgtaacagt 8580 acagatagaa agtgggtttt ggattatatt ttcgcaagta ttttatgcaa agcagaagaa 8640 agtccacgga aattatgtcc gtggacttga caagaatttt ctccaatcta aggtagataa 8700 ttttttttct aaaaaaaaaa ggaatattgt gcttatccag ttccgggctg aaaaaaaggc 8760 tagagaagga aattttcttt gctttttatt tgggtaattg attagtcgtt gcaactactt 8820 ttaccaaatt cgcttatttt gttaattgga aaactgattt tacattattg agtcaaaatt 8880 gcgtgttttt ttaattggca ttcagtatca taaatttttg ctatgaataa aaaagtcgta 8940 taagccaaat aaatttagtt gtaattcatc atcaaaattc aattgtttat tcgacgtttc 9000 agttgtttat tattattaaa cttgctttaa aaaataatag gctcgacttt accgataaca 9060 gattagaata gtggagtagt ggagtaaagc aaaaaacgtt gttaactaaa ttctatcgcc 9120 gtacaatgtc cagtatagtc tatttaccgc ataagtttat atggagtaaa tacaagatgg 9180 gagggggggc tttaaaaaat ccgcaaaatc gtcttaattg aaattatatg atttaccgtt 9240 tcgtaacaat agcatcttgc taaaacagct tcacaatgtc tgttatgaat aggaaacaaa 9300 tcggaaatca tttttaaaaa atgaaatcaa atttttgatg gtcccataat gtattttatc 9360 aaacaagagc attttgtatt ttaagtttgt tgaaataaag aagtctttgt aactaaataa 9420 accgggaaaa tgaatttcca gaagcttttg aacaaacatg ccaaattgtg ccttaatttg 9480 tttgcattta aattaacgaa aggtgctatt gattttgagc gtgcaactaa ttgaatggat 9540 gtttttgaac aaaaaggttt attattataa tatatggatt caagcaaact ggacttttgc 9600 gattaaaaat ttttaaatat ctaagtgtca acgaacgaat ttcggaaata gctctcaaat 9660 gaattaagaa caattttact atgagaaaaa aaatctaaac ttttattatt tcgaaggtag 9720 cataaaaatt gtattattag aaaataccct ttgatctgca aaaggcaaac gttaaatttt 9780 taaaataatt taatttgcga aaaaaagtta aagatgtcta ctgaaggcaa aatcttaaca 9840 ttttgtaatt tgttgttaag atgacatatg cttaaggtcc cgagggtttg aatttgttaa 9900 aagatcttca tttgtggaaa aaaaaataat tgaactttga aataacgata aaataggtga 9960 caaaaaagca atgcaagtac ttttatttca tgtcacaaag aaagctgtga tgcaataatg 10020 ctgaataata ctaaaaatga aatggtaggt cctgaaattt tcgactagac ctttttgttt 10080 ttttagtttt ttgcttttac caaagatatt gcatataatc attgttaaaa tgaaataaat 10140 aatgaatgaa tgaaatgaac taaaaacaaa attcattaaa aaaatgcatt caacctagcg 10200 atgaagtgat tttgcaactt tcgaattaaa ccggttaaga ctttaaaacg cgtttttttt 10260 taaaaaaaaa aaaaactaaa agttttgtat tggtaaatta aatttggaca ggttgctagt 10320 aataaatatt tactgcacga taatatagac aagcaagaaa agctgtgttc atttaagatg 10380 cattaataca ggattcgtgg ttagaagatg ctaaatcgat agttaaaagc attcagttca 10440 agttttcctt ttaaagattt tagaaacaga aatgtcttgg ttgggcaaga aaattacctg 10500 aacaaaaaag caaacctgcg aaaccataaa cttgtgagag gctcaaaaag taatgcgata 10560 cgcagctata tttatcaaag cctattcgaa ctaattgctt taatcctact taattctata 10620 atatgctaca tttttgtggc atatcttttg ttcaaaattg tattctgaat gcagcaataa 10680 gttatgcgtt gcgtcgttac gtatattcaa aaacagtaaa attataacaa cttctcataa 10740 tgcatcaatt taaaggtact catagcttta aaaataacaa ttccaatagc attatattaa 10800 gagcaattgc atttttttta tcaagtcaaa ggtatatcga agtgttccgt ggagcaacaa 10860 aacacgattt aacgattatg ttctttggta aaaaaaaata attaaaagtt catgacgttt 10920 gtcatttatc aaacaatttg caaaatgtat gaatggccgt tttttttatg ttaatagtaa 10980 agctatgttc agaagaactt gattgctttt tttatttgat tttattaaca tcagcattaa 11040 atcagactct aaaatatttc aacaagtccc atgtaaatcc gttaaatacc ccaatttttg 11100 aaatttgtta aagaggtatg taagcactag aatttaaaat tttgagtatt atattatttt 11160 atttaggaat aattgctatt gtcgctaaat gtttcacgga agatttagct gagcgtaata 11220 ctgtagcatt gttcgagata tatttgttgt ttgcaatttt agatttgtac tattaattaa 11280 ttatcaatga aaaattaaaa ttactgattt gttagcagag ctaacatgta tgaacaaatg 11340 atcatttgca agcttaaaaa aagtaatgtg ttggaagaca tatatctttc ctttaaatct 11400 gaaaagtagc ttttaaaaat attctaaaga tctatatacc ccgaaaagtg acatattgtg 11460 agcttattca tcatatcgct aatgactaac ctgaatgtat gcttctatac tacattgctt 11520 ttaaagttaa gggtaatggt tgtttaattt aaaataccct caagagaaat tcgtcttcga 11580 aacttaccaa agcttgaaaa gcctacaata agcagtaaat gtacttattt aaactactgc 11640 ttttgtagta tgatgagcag aaaaataaca atcctagaac ccttatctca cgagttcgct 11700 aaagtaaaaa cagtatttaa tagaattcaa attttggtat tctttaccca ttcgtttgac 11760 atttcaattt ttttactgat ttaattgttc gctaaaataa ataggttgtt ttttagaatc 11820 agatactgtc actcataata tctttcgttt agttattaaa tttattaaaa tcatttctgt 11880 tctatgtttc tttttgatga ttggcatcca tagtctagtt atcgtatgaa tctgctcaca 11940 ataacggtta agtcatctgt tatagatgtg ttccgtatat ccttagaacg atagaattca 12000 gattatgctt gaacatatat taagtaagaa tattttgttg acttgctaaa aataaagaac 12060 cattgccatg aaaatgtgtt cttctgtcga ataaactact taacagctta ttatccgaca 12120 aaaaattttg atcagtaatg aaaaattaac aaaaatacat tttttctctt tcggttgcca 12180 gactttgata ttcagaagaa agttaaagca tccgaaaatt ggaagggttt tataaattta 12240 aaaattaatt attacttctc caacttttgc catattttac atgttcaaca aatataaacc 12300 gcaatttaaa tcaatttgga aatttgaaat ttattttata taattaaata aataagtccg 12360 taagcattta actttgctgc gaacagaatt gcgaactaaa cattttgggg tttttattta 12420 tgaaaaatgt aaaattattt ttttcgctca taaaaaggtt ttatgtatca acaaagatcg 12480 gaattaacat tgacaaatga agaaggcacg gacaaagtaa attagtgcaa aaagttcaag 12540 tcagaattct cataaatttg ttaaataaat tgacttctcg ttagcaatag tatgattttt 12600 caattcaaaa ttatatatta aatttattta caaggacttt aaagtccagt aaaagatggg 12660 ataaatcctt aaagtcaata ggccacgaga ataacatcgt ccgccctaaa acctacatca 12720 tccataccac ctgtctctcc atcatattca ggagatgtga tccataatgc tccatattgg 12780 ctaacgtgta aagtctgaat ttcccctgaa gaactctcta caaaagtgaa ggttccgtta 12840 ttatttttga taatgtcaaa ggatgaatct ggatcatcag tgtatatcgt atatacaggt 12900 cgtacgcaat cacaagttaa tattctttcg acagtaggat cataataaaa aacattaact 12960 gcttcggtgt ttccctcagt agatgtgtac atgttacctt cgtctggatc ggacacatta 13020 gtattcttat aaacatatga aggattgatt gaatcaccca cgagtctcaa gtgaaatgag 13080 ttctctggat tgcatccaca agacggtgtg ataacctcca ctaaacctga ctgagttcca 13140 gaaactgttt gtaatgtggt tgttgagaca gggtaactag atccagaagt caacgtagtc 13200 gtaatataac cagcagtcgg aattaccact tcaacagtgt caatactttg atcaacaaac 13260 gtagtggtaa attgcgttga accagaaatg atagtggttg taatggtact ggcagaaatt 13320 gaggaacttg atgggatagt tgaattagaa agaatagatg aactagtcgg ggtggaagaa 13380 gttgtcggca ccggtgaagt ggtagggata gttgaattag agagaataga tgagctggtg 13440 ggaacagaag ctgtgatcgg ggtagatgaa ctagtagaaa tagttgaatt agaaagaata 13500 gatgaactac ttaaagattt tgatcccgta taaggataat tttcagatgt gttagatgca 13560 acattggaag ttggatatat cgttgtggtt ccagggactg ggccattagt ataaattgta 13620 atatattgag ggcaggcagc taataggttt tcgtcctgct cttgtagtga tgcatagtca 13680 aacgcgaaag cgtttaccaa caaacacaat gtcacaatac atttaaggca aagtgacttt 13740 aacgaattca ttgtccgtaa ctgtcagttt gttctaaact tttagtcacc tctattgcgc 13800 gaagagtgtg aaaggatttt caaaaatcaa cgactttata tacttgaatt tttatgatat 13860 caaaaattta tcacgatacg ctgaggttat ctttgctgga ttaaatacgt tattcgagtt 13920 cacaaaagca gcaaatatcg aaataccatg aacacgaaca tgttgtaaaa ttggtgtctg 13980 gtcgcttttg ggaaaaacac atattaaggg atgggaaagg agatggctcc ccaaagcata 14040 ttccagacaa gttcagtata cattcgtgaa gcatatcaca ataccagtga aatcttctat 14100 aggtgtaaaa acaaaaaggt atgttgagtt taagactatc atcgatttgg ccatcccgaa 14160 caactagtta cttcacttat taaatatcct taagagcgta atgtatatat tattaaaaaa 14220 atgtaaaact caagtaaagg ctgtagttca ttttggacgt aaatttagtc tttgtaccat 14280 aaattttatg atcactgcaa cactacgtct atctgtatca ccacataatt cagggataag 14340 taaacgggtg atgaggtaga ttttacttcc aaccacttaa ctaagtatta gtaggaaatg 14400 gtaaccatca tagcaagaaa attttaagta gttatgttta cttttctatt tagcgctgaa 14460 tacgaaaaac aattgttaat ccatttattt acttacaagt aactaagctc ttcttaattt 14520 tcatttcatt tcaaaccagt ttttttgtgc gtaggcctgt aaaagagttc agttggaaag 14580 ccaagcacaa cactgatgca ctaaatttcg acaagtttga aacaaaaagg atacaatgct 14640 atatatcaat gggaaaaaaa gctttacttc attgttgaag tctctcccgc atctgtttat 14700 tggatgagta caaatgtgca tctgaaaaga tttgttaaca gcacgatgat aattaactac 14760 cgcattctaa tctgctaagt attggggatg catcgttagt tgacaaatca ttaatttcgt 14820 ttttattact taagtaataa acagaccttc tagcttagaa aataagctaa caaaagccat 14880 catttcctta cactaaaagt agatttagcg aaaaacgtta aaactctgag taccttaacg 14940 aagcaaaatt ctcccacgcg aatttaacga ttggtgctaa cgaaagcgga agtacgtaaa 15000 cctgaaaggg tattacagct gcattcggta aataaaaatg aagttcggta gggaattctc 15060 tcacataagg atattgagga gtaagtagta ggaaaaagcg gatgatagca ttggaaggga 15120 taataaattt ttgtgggaaa tgaggggaag agggaaacga gcaactgggg aaattgatag 15180 gaagaacgtt gatggtattg ttaagtgaat gaatagaaac tcagagactc tcacaaatca 15240 tttaaaaaaa ttttcactag tcgaaagttt ttacggtatt attattttca tcttttcaaa 15300 gcattatccc agtcttacca cgagatgttc ctacataata tgctgcgctt ttcataaaag 15360 cacatatcct gcaaatatct cttccattta agattatttc gtttatgcct tacccatgga 15420 tctacgattg atatcgaagt ttgattgaat tatgatttct ttgatacaat cacgagttat 15480 gtaaatgata tctgttgtgt tctcgtttta gtatattggg tttaaccttt tcaaatttgt 15540 tgctaaattt atatggcaca gatcagaggt cgaacccttt tattattgaa ctacttcttc 15600 ttcggcagct ctctagttga gtagctggca gttatgctta ccataattga ttagacatat 15660 caatgaactt aagcatgtag cggtgctcga ccgttcagac taaaataaca aggtagggtc 15720 attggagaaa aaatcataaa gaaagacatt tcgatatttt gcaacgtcgg gaagcaaatt 15780 ggctggggta ataacaacga ccgttctcat tagtttgaac ttattaaaaa ggggaaatag 15840 tcattgaagc acttagtttt tgttttgaat gctaaaatgg tataatacgt ctgtcttact 15900 aaatatagct accagtctat ttatatcaaa cttataaaag ctaacaaact aagatcttcg 15960 catttcaagc agaaaatcat tgatttgtaa tatatattaa tagtattttt gtcaatttga 16020 gtattgttta ctatttaaac ttttcttgaa gcaatttgaa gatcctaagt tactaacttt 16080 tgctaataaa aaataaaaag cttaggaata tttacacaaa catagaatca atttcttttc 16140 ttcttttgtt tcccattttt ttaaattgaa caaaaatagg gaaaatctta aagaaagcaa 16200 gcaatttatt atgttatcga attatcaaat attttttact tcttcttcag cattataatt 16260 tcctaactag ttttgtttac aatcaagaat ataaaattaa tgcaaatgat caaaatttgc 16320 attcgtaaga atttttattc aagtgagttc aactaattgt tgtgaggcct aatttatgtt 16380 aatccatact tcacaaagat gacaatcttc gaataaacag ctgaaattat gcttcatttt 16440 atatttagtt tgtttttgat tttattttgg aaaagaatta tagttataaa attttatata 16500 ctggatactt atacttttcc taatcttagg acttcctttg tcgtctttta ccacctcagt 16560 taaggctttg cttgttgaca taaagtatta ttgaaactag agaaagtact atagacgagt 16620 ttttctgttt tattaacttc gaaattttta acgtgataaa cattgctaag atgcgcaaag 16680 tttcacttta gatggaacgc tagacatcca ggtgcgttta taagacgaga atcataacta 16740 tagtttatat ctaaaagttt gatatttcta aaatgatatc gtttcataaa actacaaaat 16800 atgaaaaaat ctcagtaggt attctttcaa ggtcttctct tttattgatt acagaacaca 16860 tctacaacag tgaattagag gtttgcttgc ccttcctaat ggactgaaga cacttgaccg 16920 gtgtcgaatc taaactccga gttcaagaat atttaactcc gattaattta tcagatgtta 16980 ttaagcaaca taatgagatt cagcgcaaac gttattagtc aactaccaac acttttatag 17040 atggtgatct gatatcctaa cattaacttt attttgaatc ctacatagcg ctccgattac 17100 tctacttagc cctgtataga aagacttaag catcgctttt aataaagtat ttggataagt 17160 atacatgtaa tgatcaccgc aaacaaaggc ttgtctctgg ttttgcttat cccaaattta 17220 ttcgctttag ttagcggggg cttacaatat gtttttgacg ttaggagacg gatctttcgt 17280 cctcactttt cgcaattttg gaccatctgg atgaagttct tttcgatagc acttgttatt 17340 attacacaaa tatatgtggg atataagaca aaaaacatcg ggtggaattt tttttcagtt 17400 gtaacttatt gtttcgtatt atttttacag tttgctgagc aatcaactct aagagttccc 17460 atggcttctc tattgatatt ttggcttctg aaagtagtta cctcactttt gattttgttg 17520 ttcagtccct atattgcaat taccagtatg gctcggttgc ttactttaat tactctgttc 17580 tgctcgctcg tatgctttat tagtgaggtt tatgtcccgc cttgcaatcg tgtctggtat 17640 tctgatgata caaacgaagt tgaagagaag gggataagac cttctgaagt tcgatatgcg 17700 aacatattct caaagttatc attttcttgg atcagttctt tcataaaatt tggttacact 17760 aactatttaa aggaatctga tgtttggcta cttcctccag atgagcgatc tggcaattta 17820 ataattggtt ttgaagactg gtggatatac cattcgaaga ataaacgaag aagtctgttt 17880 ttatggaaac ttttattttt taatcattgg aaacttgtag ctctaattac catcacaaag 17940 ttgattcaag atgtacttgc ttttgttcag ccaacattga ttcagaaaac cattctcttt 18000 attagttctt atacttctcc caatcctgaa tccccaagta gaggttttat aatcgctatc 18060 ttggttcttg tcgctaattt cctccaaact ttattactac aacaatataa tcagcttatt 18120 atgttgcttg gaatgagatg gaaaacggaa ctacttgcat ctatttatcg taaatctctt 18180 cttctatcaa gttcagcacg ccaaaatcga tctattggtg atataataaa ttacatggct 18240 gtcgatactc aaaaaataag tgatctgccg atatatttat tcattattgt ttcaggtcca 18300 tttcaaattg ctttagctct ttcaaattta taccacctta tgggatatag cgcttttacg 18360 ggtgtcgctg catccgttat actatttcca tgcaacatta ttgtcgccaa tgtgtacaag 18420 aagtttcaaa gtattttaat gaaaaacaaa gattcccgtt ccaaattgat gaccgaaatt 18480 atcaataata tacgcagtat taaactttat gcatgggaaa ccccattcct tcagaagcta 18540 ctgcatataa gaaatactaa agaattaagt atgttaaaaa aaattggttt catcactgca 18600 attggtgatt ttgcctggat ttttactacc attattgtta caactgttgc ttttggagcc 18660 tttattattt tccatgggaa aactcaagct ctcactgcgg atatagtatt tcctgctgta 18720 agtcttttca acctgttgca attcccattg gccatgttac ccacagtaat tagttctttg 18780 ttggaagcat ctgtatccgt ttctcgaata tatgaatttc tcatagcaca agaattggat 18840 tacaatgggg tacaacgatt tcccgctaca gagattcctc atgaaatttg tcttgaaatt 18900 aaaagtggca ccttcagttg gtctaaaaaa acactaaagc aacaagtaac gccaacttta 18960 cgtcaaatta attttgtcgc aaaaaatggt gagctgactt gcatatttgg caaagttgga 19020 gcgggtaagt cttctttgct agaagcatgt atggggaata tgtataaaaa ttcaggttct 19080 gttttccaat gtggttcact agcttatgca gctcagcaac catggatctt tgatgcaact 19140 atccgggaaa acattctctt cggatctgaa tttgatcctg aattgtatga gaaaaccatt 19200 catgcatgct gcttgaaacg tgattttgaa atatttactg aaggggatca aacggaagtc 19260 ggccaaaaag gtgcatcgct gtcggggggt caaaagtcga gaatctcact tgctcgtgca 19320 atatattctc aagcagacat ctatcttctc gatgatgttt tgtcttccgt agatcagcat 19380 gtaagcagag atttaattaa aaatcttttt ggtccagaag gtttcttgag gacgcactgt 19440 gttgttctta caacaaattc tttaaatgtg cttaaagaag cagactcaat ttatatatta 19500 agcaatggaa aaattgttga aaaaggaaac tatgagcact tatttgtctc gacaaattct 19560 gagctaaaac aacaactatc ggagttcaac gatgagaagg acacgcagcc tttacccgaa 19620 catactacat cgtatccaag tactcaaatt tctttggctc cttcaattca tgtcgaaggc 19680 ttagaaacgt attcttcaag tgaaagaaaa gatagttcta ataagtataa atctagaaag 19740 agaaatccga tccgccaaaa agtgacagaa gatgataagg gaaagtgtgt tgctcaaact 19800 gatgaacttg ttcaacgcgg taaggttaaa tggcatgtat attggatgta ttttaaatca 19860 tgttccatcg gcttaatttt actatacttc ttcttcataa taagtggtat aatgatgaac 19920 gtcgcaacca atgtttggtt gaaacattgg agtgaagaaa atggaaaatc aagttcagaa 19980 cttaacccta gcccttattt ctatcttgga atttatttat tttttggatt tttatcatgt 20040 gctttcattt caagtagtag cttgactatg acggtgttgt gcggtatacg aagcggtcga 20100 tatttgcatg attcaatgct taagacgatt ttgcgtgctc cgatgggctt ttttgaaacc 20160 acgtctagtg gaagaatctt aaaccgattt tcgaacgatg tatacaaagt tgatgaagta 20220 gtttcgttga catttatgtt tttctttcga aattcaattc aagtgctctt cattttggga 20280 gttatctgct attctgcacc attatcttta cttctgatag ttcctctgtt ttttctgtat 20340 ctttataata gggcttacta tgtgcgaact tcacgtgaat taaaaagact agataatgtc 20400 accagaagtc ctttatacgc acatgttcaa gaatcattaa gcggtttatc aacaatccga 20460 gcgtacggta tgcaagagac tttcgttgaa gaaaatgacc tacgaattga taccaatcat 20520 cgtgtatggt tcatgttttt cagttccagt agatggcaag ctattcgagt ggaatgcatt 20580 ggagacttaa tcattttttg tacagcattt tatggaatcc tttctgcaat taaaggtagt 20640 cccaacccgg gcttagtggg tttttcgctg tcatatgcaa tacaaattac tcaaggtctc 20700 tcatttatag tgcagcaatc tgttgatgct gaaaataaca ctgtttctgt agagagaatt 20760 ctagaataca ttaatgttaa gagtgaagca ccggaaatta ttccagagaa tcgaccacct 20820 tgtgaatggc ccactgatgg ggcagtctct ttcaatcatt atagtgctaa atatcgtgag 20880 gacttatcct ttgctttaaa taacattaac attgaaattt ccccacggga aaagatcggt 20940 atcgtcggtc gcaccggggc aggaaaatca actttggcga tggcattgtt tagaataatt 21000 gaaccaactg aaggaaaaat tgaaatagat aacgaagaca taacgaaatt tggattatac 21060 gacttgcgct cgcgattatc tatcattcca caagaaagtc aaatatttga gggcaacatt 21120 cgagaaaatc ttgatccgaa tcatagacta actgataaaa aaatttggga ggtattagaa 21180 attgcttctc taaaaaactg catttctcag ttggaagatg gattgtattc tagggttgct 21240 gaaggaggtg caaatttttc gtctggtcaa cgccaattaa tatgtttagc aagagtttta 21300 cttacttcga cccgtatatt attgctggat gaggcaacag catcagtcca tgctgaaact 21360 gatgctattg tacagcagac cattcgcaaa cgcttcaaag atcgtacaat tttaacagtt 21420 gcacatagaa ttaatacggt aatggattca gatcgcatct tagtcttaga tcatggaaaa 21480 gtggttgaat ttgatgcaac taaaaaattg ttggaaaaca aagactcgat gttttattcg 21540 ttggctaaag aaagcggtct catttaataa tttttaatcg ttctttacct gtattacaat 21600 aaatctagat atcatatcat acttgcaatt gaagctattg gttttttaca cgttcagaaa 21660 aatatatata tacaaaatga agttttcttt atgtttacat gataattttg ttcgtaaaag 21720 cagtatcact gatatctacg gtttaattcg ctaacttttt ggttatctac tcttctttgt 21780 acgtttagcc tgatattctt gtggtaatga atgaatactt aaatttttgg aaatgaatat 21840 gattagatta tatggcgcag tacaacaaat agatttaaaa taactcatac agtatattaa 21900 aaagaaaatc aaacgtaaag gcttcgggat ataaagtgat caaatttcta agaaaaaaaa 21960 gcgttagcat tcgaggaggg taagtatgat tagatgttta cttgaaatta gagtgttaaa 22020 aaatatggct ttatatcaaa taaaatatcg ttgcaaaacc gtgcaatgct tcgtcaaatt 22080 gacattcacc tagactttac tagtttcatt cgcgtattag atttcctgtt aactcaaata 22140 gaacgataat attctggtac cgtagcaatt cataaaatta aattcggcgg aataacgaaa 22200 gttgtaatta ttaagtccta acgtctctat caaaagttag caccagcctt aacatcattg 22260 cgtacatttt ctttctaaac ttttagggta acattttgga atatactaat gtttacaaat 22320 tcaataccaa gctacatcgc tccagaacga tctagtgaac ttaaaggcat tgcttccaaa 22380 aaaataaaat atttttcctt aaaatgcctt tcagagcagt caataaaaaa ataaaaaatc 22440 gaacaaagga acatgaaaag aagcacgaaa aaaacctata taatttgctt catttgaagt 22500 gtagagagta ctttactttt agtgaagaat cgttaacaat tcctattgta agtttgttag 22560 cttctattta tgatgtcact gtaattaaat tgatctgtcc aataatattg attgaattaa 22620 ccttgatcat ataaagttga aaatgcggag aagatcgtga agaaccagag cttttgtgag 22680 cttggtaagg ttaaccgggg aaccttcgca acatgaacga actttaatag cattctgcga 22740 tttaaatctt atttgctgtt ttttaaaaaa gcaaattata acttaaaata ttaagacccc 22800 catgtgacaa aacagttctg gccttttaaa aaagacggtt tttagtatct taagcaagaa 22860 gaacttgttg aaatttgctt gagaaaatgt gcgttacaag catttttatt aactgaaaat 22920 gttcagttgt tcttaataag cattaaatct aatttgtgtt actgtttgtt ttatgaaaat 22980 gaattcaatc atgtatttac tttaaagttt ttcactactc cacgaacagg ccagccaacc 23040 cctcatcgtt tcgaacccct ctatttcgaa agggtaatta tcaacaaagg aatcaaaatt 23100 ttatttatat acatactctg ttcacgaatg aaattgtctt tattttctga agctattaaa 23160 agtgaattac aataattcgc ctatatctgc actgtcgaaa taccaaagaa attaatatca 23220 ttttgaatta ttttttttta atacaaaatg gctaaagtaa ctggattgcc tgaatttgaa 23280 gacttacata ctaaaagaaa atggatgctt aatcatatgg ctgcagcttt tcgcatgttt 23340 ggtagaaatg gatataatga aggaacagca ggacatgtta ctgtaaggga tccaattgat 23400 gagaatactt tttggataaa tcctttggaa gtcccctttt ccttgatgaa gcctagcgat 23460 ttggttcata tcaacagcga tggcgaaatc attggtggaa gcaagatgaa gtataatact 23520 tcgggatttg ccatccatta tgaaatgcac aaagtgcgac ctgaggtaat ttgtgtttgt 23580 cacgtacact caatttacgg taaggcattt tcagctttgg gaaagccatt ggatatgttg 23640 aacacagact gttgtgtgtt ttataataat catggaattt attttgacat ggatgatgtg 23700 atatcgatgc cagaagaagg aagacgtacc gctaaaggat tagcagatta taaagctgtt 23760 cttgttcaga atcatggcat tatgacagtt ggtactactg tggatgaggc agcatatctt 23820 ctttcattga tggagcgatc atgccaaatt cagttgttaa ttgatagtgc aaccaaggtg 23880 ggagaaagaa agcacgttca tcccactcgt gccaaagcta ttcgcgaaaa tgctgataac 23940 ccagtgggtc tatacactgc tcaacaaccc aactttttgt atgaagttgc ttgttcaaat 24000 ggggaactag aaataatttg agtaatgcat ttgtctgata cgttcttacc tcaactctac 24060 tgtacgtttt tacagtattt gtagcaaaaa tttaaaattc atttatgtcc tttttttgct 24120 atttaaagcc tatgtaatgt caattaaatt tttacaaact cccctttagt taaaacgcaa 24180 aatatagcgt agaatgtaac ttttgaaagg tactttaacg taacaatgtt tacgaaccat 24240 ttcaaatatt acgataattc gttaaattat ggtttcagat gacttttaat attcatttgg 24300 gttgtgcagt ttcttatgag tgaatagcgt tgaaaagcag tgcgttgtta tattgcagcg 24360 tgtaggcaac tgaataatag gagatgaaaa taattctcat tgaagtaata gaatctatca 24420 ttgaagttca agtcgtattt gatgcactgt aaataaaata ttttttggag tctagcaagt 24480 ctaaataatt accatctttt gtgtggcaaa tgcatcgcgg cgtagcgaac gctgctaaca 24540 taccattttt ttcaaattga tgcgcattaa taaaatagcc agtgttcaat aaggaccgag 24600 tttgctttat tgtatatgat tacagagaaa ataaaatatt tttgcttttt ttttgttatt 24660 ttctatcatc ggcttaataa tgattttatt tggctcatga aaactgatta tgaagctgaa 24720 gcactctctt atatatataa atgaatgaat ggcgctactt tatggcatgt tcgtttattt 24780 gtttaactct cattgtttta tcataatgta gtaattcctt atatactaaa gttattccaa 24840 aaatgtaaat ttatcatata tgattataaa ttgaagtata taagcgttca cgctttaaaa 24900 atatatatat ctaaagtcgc tgctctattt agtcatagta tttaataagt ataatatgtt 24960 gtttaaaatc tgtttgtctt gtttcaagaa ttataaaact aagacctttt ttattatcgc 25020 atttgagcag ttttgcatgt acagtataca tttggttcta agcatttttg agaaaaaaaa 25080 ataaatttga aatttttatc ataatttttc cgatctttct ttgttcaaaa aacctctcac 25140 tataggaaaa atattttttt ctccatcatc attttcgaca ctattttaat tatttttatt 25200 ttgcgaactt aatacgtcca agtttgggat gagagctatt gtggaataga gggtaacttt 25260 ctttgttcat ttttgtttta tttgaaagaa gaaacaatcg ttgtgttagc cacgaggaaa 25320 atgcaaaaat ggctatgcaa ttattaccta aatttgcgaa atggaatata cactaaaaat 25380 agagtaatgt acaagataag tagcggatgc aattaacata actagatatt ggtccgactt 25440 ttatatttca taaagtgttt gatgcctcgc gggcgtaata tatcaatgga aaggttacag 25500 gagaatagtt agaacaaagc aatgattaaa atgaattaaa ggcaaaagta aggaacttgt 25560 gttaatcgaa ggaaaagaat tttatttaaa gctcactggc ttttttaact accttcgttg 25620 taaaagaaag ttacaggatt aatttgaacc aaaaatgcaa atgtcaatac aggctttgtt 25680 attcgatatt gaatatttta tgctctaaga tgcaaattac aaaagggtta gatatcagtc 25740 agtatataat tttagtgaaa atctaatggc atcagttttc tgatgaatct gtatttaaaa 25800 ttgcaaaatg ctaaaactac catgcgcaac attcacatga ttaattaatg ctgtgcaagc 25860 cttagcatcc aatttggata atcgcaataa agagatgaat taattaatta atttattaac 25920 ataataaaga aaaaagaaaa agaactaaaa aaaaatttta tttatttttt ttttttaaat 25980 ctacggaact aaatctagtg 26000 //