ID SPBC30B4 standard; DNA; FUN; 25282 BP. XX AC AL031262; XX SV AL031262.2 XX DT 12-AUG-1998 (Rel. 56, Created) DT 08-AUG-2000 (Rel. 64, Last updated, Version 4) XX DE S.pombe chromosome II cosmid c30B4. XX KW chromosomal segregation protein; Glucose inhibited division protein a; KW mitochondrial outer membrane protein; transcription factor; KW U14 small nuclear RNA gene. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-25282 RA Lyne M., Rajandream M.A., Barrell B.G., Hilbert H., Duesterhoeft A; RT ; RL Submitted (11-AUG-1998) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and QIAGEN GmbH, Max-Volmer-Str 4, D-40724 Hilden, RL Germany XX DR GOA; O13670; O13670. DR GOA; O13671; O13671. DR GOA; O74363; O74363. DR GOA; O74365; O74365. DR GOA; O74366; O74366. DR GOA; O74367; O74367. DR GOA; P87179; P87179. DR SPTREMBL; O42995; O42995. DR SPTREMBL; O74363; O74363. DR SPTREMBL; O74364; O74364. DR SPTREMBL; O74365; O74365. DR SPTREMBL; O74366; O74366. DR SPTREMBL; O74367; O74367. DR SPTREMBL; O74368; O74368. DR SWISS-PROT; O13670; Y079_SCHPO. DR SWISS-PROT; O13671; CSE1_SCHPO. DR SWISS-PROT; P87179; YB1E_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 80% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c30B4 overlapped at the 5' end by cosmid 3D6 CC and at the 3' end by cosmid 27B12. XX FH Key Location/Qualifiers FH FT source 1..25282 FT /chromosome="II" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c30B4" FT /map="IIL" FT misc_feature 1..931 FT /note="nominal overlap with S. pombe chromosome 2 cosmid SP FT BC3D6" FT CDS complement(1..1034) FT /db_xref="GOA:P87179" FT /db_xref="SWISS-PROT:P87179" FT /label=SPBC30B4.01c FT /note="SPBC30B4.01c, len:344aa, similarity, YNL283C, FT YN23_YEAST, P53832, glucoamylase III, (503aa), fasta FT scores, opt:567, E():1.9e-16, (37.2% identity in 366 aa ove FT rlap)" FT /partial FT /gene="SPBC30B4.01c" FT /gene="SPBC3D6.14C" FT /product="putative glucoamylase" FT /protein_id="CAA20314.1" FT /translation="MNTQYGCYLVDSSLTEQGTFTYLDPAYCYNNICGGSDNIAFVAIR FT NNQCYCGSTLTATEVSSSLCTTPCPGYGSLMCGGDLYWSVYLTGNGVLQTTVSSSSVSS FT TTSSSSSSSPSSSSTTTTTSPSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS FT SSSSSSSSSSSSSSVPITSSTSSSHSSSSSSSSSSSSSSRPSSSSSFITTMSSSTFIST FT VTVTPSSSSSSTSSEVPSSTAALALNASKASNHTSLNAGAIVGIVIGCVAFAVVMALCI FT FLYFYFRRFKIRMSDSANEGKYPSYASELDSRLDPAMMNRKSSESLADSQDYSRKILRV FT TNLN" FT misc_feature complement(223..258) FT /note="PS01186 EGF-like domain signature 2" FT misc_feature 591..671 FT /note="Match to protamine_P1 , Score 42.48" FT CDS complement(2450..4537) FT /db_xref="GOA:O74363" FT /db_xref="SPTREMBL:O74363" FT /label=SPBC30B4.02c FT /note="SPBC30B4.02c, len:695, SIMILARITY:Saccharomyces FT cerevisiae, YNW4_YEAST, hypothetical 86.9 kd protein, (767 FT aa), fasta scores: opt: 292, E():2.2e-08, (22.3% identity FT in 663 aa)" FT /gene="SPBC30B4.02c" FT /product="protein with R3H and G-patch domain" FT /protein_id="CAA20315.1" FT /translation="MSNFDDLQILDQLQTSARFRGDTRIRRFKGSNNSKSPFGLNPSSR FT ISQWPRITFIRAKDNYNPAEELCQLIDEQNAHNEAKHQSKEIMLPKETNVKSCEDLSKT FT GEIKALDIVLFKAITSKGDTLKVKKIPEYAEAFDTTKNVEVSSFPEKSMNENVLIQHSL FT NLAPSDKEISSTEESEQLCYKEQESEKELYSKDNDDSLDILNVPNLVNDDIANNNAAPP FT PPLAQAQEQLSTENEDEFDIDDTTDKMTTFTMNKFADLSVLEEDDDDEDEDEELEGEKE FT EEEEEKEKPEISNYDETEGKVNFSLEDSESLEFDEGSDDYDYAKLTTELVGNTDSLAED FT EDDILEEDEDEDEEELLAIFDASDDSEIEAYLSIGDTLQNDFTIYDYDSEDEEYNNPST FT QKTEKVSQSKKGAKVKEEKGLKKDRKLPKKMRKAQKKLERKAGKAVAARMGDAFSNSLD FT DESMNLYAELQEQWLKDKSKKARRRAEREKLRSEGLLGKKSKKKLLRESQKPSSSDSDN FT ASLTRIDKIFINDVYQRMQQFKHSAIEEISLPPCRKYVRRLVHALANDLNLKSRSYGSG FT NKRYTMLSKTHKFDASSVDLVSLTRIMERLQTRVEYQSFSKSGRKSRMTVSSVRSSKAT FT RVYDGQIVGEDAPEISKENPGRRLLEKLGWYAGKGLGHPENEGSKDSLRAIVKVSRSGL FT G" FT misc_feature complement(2453..2584) FT /note="Match to G-patch , Score 42.94" FT misc_feature complement(2792..2947) FT /note="Match to R3H , Score 73.55" FT CDS complement(5330..6505) FT /db_xref="SPTREMBL:O74364" FT /label=SPBC30B4.03c FT /note="SPBC30B4.03c, len:391, SIMILARITY:Arabidopsis FT thaliana, O65609, hypothetical 83.3 kd protein., (748 aa), FT fasta scores: opt: 218, E():8.5e-06, (22.5% identity in 404 FT aa)" FT /gene="SPBC30B4.03c" FT /product="possible LIM domain binding protein; low FT similarity" FT /protein_id="CAA20316.1" FT /translation="MVANYASMMYHNGSNILGYGVLRLLQYNEQLMSGWESTMKDDIGY FT WRRFVHDFYTEKGTFRYNIDYKDSPNQEPKLFELSYAALPRFLYLSYCGKLKKMSFLLG FT NTKEFAIPNNGYFVESSRASILYQYQGGVQVIVSGHLRAHFFRAPLLKLDSLEFSAVGH FT SEYLLRELMTNASLALSQSRPPQNQIQHDGVKSEDPSSESVNINSSSSLLPDSPVNEYG FT LEPHIMRFMEITETISGMRDLIAFTLAQRSGPTSALHKFATALQQQHQMQKSTSSNIPY FT ANPAPSGFNGSPRNGDVASLASNYRYAKQPPTMPANAISQANRLLDQNNIPNMDPSILP FT QSMPIASVPPYSLQGIKRQGTHSPMVEGENPNNNPNFYSSDMLNAQKRTKV" FT misc_feature 9128 FT /note="dicrepancy: with published U14 small nuclear RNA gen FT e and with cosmid c1268 sequence - additional T residue ins FT ertion at base 9128" FT snRNA 9143..9254 FT CDS complement(9636..12233) FT /db_xref="GOA:O74365" FT /db_xref="SPTREMBL:O74365" FT /label=SPBC30B4.04c FT /note="SPBC30B4.04c, len:865, SIMILARITY:Saccharomyces FT cerevisiae, ADR6_YEAST, transcription regulatory protein FT adr6, (1314 aa), fasta scores: opt: 305, E():8e-08, (22.9% FT identity in 687 aa)" FT /gene="SPBC30B4.04c" FT /product="putative transcriptional regulatory protein with FT ARID DNA binding domain" FT /protein_id="CAA20317.1" FT /translation="MNNQGFVPASDYPTAVSYPTQGQSYNTQEEQPAYPQRFSTSQGMY FT AAEYGNANMMNTSENEPNNLAHSQPFRQSPSTQRNLPNQSFDFASNGAWNGSGSVKYSS FT PMMPSSRIPFQQEKEAAMQQQQQQQQQQQLYQRQMQSREALLSQQIPPNQIGINAHPAV FT RQTPQPAPSPNTPSGNANQLTPAYAASFDKFMVSLISFMEKRGTPIKSYPQINNTPINL FT MMLYALVMRAGGSRQVSAHNFWPKISASLGFPSPDAISLLIQYYNSYLLPYEEAWLAAQ FT QQQKSLQQAKANHSANVQSRPKNYPQKPVQTTPEAVHANGSMHGSLHSKSPSPAFTANR FT FSPAAPTTVSSERNAPPYPSAPTRPTPPTVQTSSSAAPVDSAEPVAYQPIKKPIDPMLG FT YPLNVAATYRLDESLLRLQMPSIVDLGTVNIQALCMSLQSTLEKEITYAMNVLLILTND FT QKWMFPLSECQDVVDALIDVATQCLDNLLSVLPNEDLMEIADKRPSYRQLLYNCCVEIS FT QFSREDFSNSLSENKTKDSINAIDVHNSEQNLLAVFVIFRNLSHFEANQNVLVQNPDFF FT PLLIRVVKSLNFHATSLLRSSRNTLDLHKDVLIVLCQLSQNFILPNVDVARHVLLFILS FT FSPFNRKKSKTILNDTLPTSIPSYTPATHPYAGPAINAYAKLLAKDANNKTNFQAIFDN FT NPKFLDSLFLLLASVVPKFNRHCLKICERRLPLLQQSFFCLAATVSYVKQSEQAANWCN FT IGEGFFVSMLRLLILLSGHPSLNPPSRVASQYPTTNPFRYVIQSGISTVRRLLSLVEAG FT NISLSSFPKSETLLAVLLAPTTETSFLKEISNLLDRTGDSDASLENTDDKSGI" FT misc_feature complement(11382..11660) FT /note="Match to ARID , Score 60.66" FT CDS join(13740..13797,13847..16692) FT /db_xref="GOA:O13671" FT /db_xref="SWISS-PROT:O13671" FT /label=SPBC30B4.05 FT /note="SPBC30B4.05, len:967, SIMILARITY:Saccharomyces FT cerevisiae, CSE1_YEAST, chromosome segregation protein FT cse1., (960 aa), fasta scores: opt: 2308, E():0, (41.3% FT identity in 971 aa)" FT /gene="SPBC30B4.05" FT /product="putative chromosomal segregation/apoptosis FT susceptibility protein" FT /protein_id="CAA20318.1" FT /translation="MDDIPTLLARTLNPTTSKSAEEALKVWELQDSSFALKLLNIVAED FT TVDINIKLAASLYFKNYIKKHWDSEEGASIRISDEVAELIKREIINLMLKSTTIIQVQL FT GEVIGYIANFDFPDRWDTLLPDLISKLSAVDMNTNIAVLSTAHAIFKRWRPLFRSDALF FT LEIKYVLDRFCEPFLALFVQTNNLLRNGPQDAESLNSLFQVILLECKLFYDLNCQDIPE FT FFEDHMSEFMTAFLNYFTYTNPSLEGDEGETNVLIKVKASICEIVELYTLRYEEVFTML FT YDFVNVTWTLLTTLTPDEKYDGLVGKAMAFLTSVIRIRKHAEFFQQDQVLQQFIELVVL FT PNICLRESDEELFEDDPLEYVRRDLEGSNSDSRARSAIVLVRGLLDHFDQKITSVVSTH FT INANLQQFSTNPSLEWNKKYVALQLFSAIAIKGQSTRLGVTSINLMVDVVAFFENNIKP FT DLLQPAGVIHPMVLAEDIKYVFTFRNQLNSQQLIDIFPTILRFLEMPSFVVYTYAAIAL FT DQLLTVRHNHVHIFTSLLIAPHILPALNQLFLIVESASTPQKLAENDYLMKAVMRIIIM FT SQEAILPAASLLLQHLTKITEEVSKNPSNPKFNHYLFESIGALIRSLSKSGPQTVSQLE FT NALLPVFQNVLIEDVTEFIPYVLQLLSQLVEASGNEPLPDFVVNLIQPCLSPALWDSKG FT NIPALVRLLRAMIFRGPQIFISNKFVEPVLGIFQKLISSKVNDHFGFDLLDRVFTVFNA FT NILAPYINHIFFLLLSRLKNSRTERFVLRCTIFFFFVASEQTGTCGPDNLIQGVDAVQS FT GVFGQLMTSIILPQAQKLALPLDRKISALGLLRLLTCDLVLAPDAIYENLIIPLLTCIL FT KLFEMPIEQAQTDADEELFMDEIDADSMSFQASFSRLATTGGKRVDPFPQITDLKQYCA FT TEMNLANRNMGGRLSQIISTHLPGDGQSVLQSYGYVI" FT misc_feature 13798..13803 FT /note="gtaaga, splice donor sequence" FT misc_feature 13834..13846 FT /note="ctaactgatatag, splice branch and acceptor" FT CDS complement(16885..18885) FT /db_xref="GOA:O13670" FT /db_xref="SWISS-PROT:O13670" FT /label=SPBC30B4.06c FT /note="SPBC30B4.06c, len:666, SIMILARITY:Saccharomyces FT cerevisiae, YGY6_YEAST, hypothetical 75.4 kd protein in FT hap2-ade5,6 intergenic region., (679 aa), fasta scores: FT opt: 1934, E():0, (48.0% identity in 635 aa)" FT /gene="SPBC30B4.06c" FT /product="Strong similarity to Glucose inhibited division FT protein a" FT /protein_id="CAA20319.1" FT /translation="MFRTTKRYFCTSFNRRKNVVVIGGGHAGVEAAAAASRLGAKTTLL FT TKSFDNIGQMSCNPAFGGIGKGTLMREIDALGGVVSGVCDESAIQFHMLNRSNGPAVWS FT PRAQMDRSVFKKNMQKTISTYRKNLQVREGAAVSINVLTEDDGKQVCDSIVLEDGTAIP FT ASCIVITTGTFLGGQINVGLTQLAAGRYGERPSLPLSKCLSNLGFKMGRLKTGTPPRLS FT SPINISKMTEQTGDEIPETFSFLNLERDFSPALPQRSCYRTYTTELTHEIVRKNLAFAP FT HMLAGDILSPRYCPSLEAKVTRFPHKARHLIWLEPEGLDPNSWWYPNGLSNSMPEEIQH FT NIIRSIPGLENCNIVRPAYGVMYDYVIPTQLKATLETKKIQGLYLAGQINGTTGYEEAA FT AQGILAGLNAGLSALGREPVDIPRNTALLGVMVDDLITKGVKEPYRVFTSRSEYRLTTR FT ADNADLRLTPLAQSIGLLDDQTHWESFQRTKSLLDFSNKIAKEFILSPQQWSKLGMPIP FT NDGKYRSAWDLLSFTNLDLFCVISCIPKLKDIPKRVLQRLIIEGKYTYYIKRQGTQNKQ FT LNCRDESTVIPSDFDFDTLHSVSAEELMLLKTIRPATIGQLKRIQGIKPGTIIRLLRHT FT YYNPAKEAWLRKVYMPMYDMHSSEENQSTNL" FT misc_feature complement(16984..18831) FT /note="Match to GIDA , Score 926.05" FT misc_feature complement(17659..17730) FT /note="PS01281 Glucose inhibited division protein A family FT signature 2" FT misc_feature complement(17974..18018) FT /note="PS01280 Glucose inhibited division protein A family FT signature 1" FT CDS join(complement(20192..21002),complement(20047..20129)) FT /db_xref="GOA:O74366" FT /db_xref="SPTREMBL:O74366" FT /label=SPBC30B4.07c FT /note="SPBC30B4.07c, len:297, SIMILARITY:Homo sapiens, FT Q13889, basic transcription factor 2, 35 kd subunit., (303 FT aa), fasta scores: opt: 551, E():1.7e-28, (37.4% identity FT in 286 aa)" FT /gene="SPBC30B4.07c" FT /product="putative transcription factor" FT /protein_id="CAA20320.1" FT /translation="MDEFQTLKQNASWDISEDANDTPSLLVVILDANPASWYSLSKKVP FT VSKVLADITVFLNAHLAFHHDNRVAVLASHSDKVEYLYPSIAPEQKVAEVDPTKEANTY FT RKFREVDDLVLSGMKRLMSSTDKVSRKTMISGALSRALAYINQVQNKNTLRSRILIFSL FT TGDVALQYIPTMNCIFCAQKKNIPINVCNIEGGTLFLEQAADATGGIYLKVDNPKGLLQ FT YLMMSLFPDQNLRKHLNTPNQANVDFRATCFCHKKVLDIGFVCSVCLSIFCEPRVHCST FT CHTKFTVEPMSKKLHT" FT misc_feature complement(20130..20142) FT /note="ctaacctctttag, splice branch and acceptor" FT misc_feature complement(20186..20191) FT /note="gtaagt, splice donor sequence" FT CDS join(21201..21328,21575..21980,22043..22342) FT /db_xref="GOA:O74367" FT /db_xref="SPTREMBL:O74367" FT /label=SPBC30B4.08 FT /note="SPBC30B4.08, len:277, SIMILARITY:Caenorhabditis FT elegans., O44406, t07a9.5 protein., (448 aa), fasta scores: FT opt: 271, E():6.1e-11, (33.3% identity in 216 aa)" FT /gene="SPBC30B4.08" FT /product="conserved hypothetical protein" FT /protein_id="CAA20321.1" FT /translation="MESPVQILVWPFPCDEMNQKTPSTVEEIRIALQELGLSTNGNKRY FT LLIVDVEATCEEGCGFSFENEIIELPCLLFDLIEKSIIDEFHSYVRPSMNPTLSDYCKS FT LTGIQQCTVDKAPIFSDVLEELFIFLRKHSNILVPSVDEIEIIEPLKSVPRTQPKNWAW FT ACDGPWDMASFLAKQFKYDKMPIPDWIKGPFVDIRSFYKDVYRVPRTNINGMLEHWGLQ FT FEGSEHRGIDDARNLSRIVKKMCSENVEFECNRWWMEYEKNGWIPNRSYPPYFAS" FT misc_feature 21329..21334 FT /note="gtatgt, splice donor sequence" FT misc_feature 21551..21574 FT /note="ctaacagtaactgaatacttgtag, splice branch and acceptor FT " FT misc_feature 21981..21986 FT /note="gtaagt, splice donor sequence" FT misc_feature 22023..22042 FT /note="ctaacaaatcgtattatcag, splice branch and acceptor" FT CDS join(complement(22944..23609),complement(22596..22804), FT complement(22461..22551)) FT /db_xref="SPTREMBL:O74368" FT /label=SPBC30B4.09c FT /note="alternative splicing may exist using internal donors FT at posns. 22869 and 22968" FT /note="SPBC30B4.09c, len:321, SIMILARITY:Saccharomyces FT cerevisiae, MMM1_YEAST, mitochondrial outer membrane FT protein mmm1., (426 aa), fasta scores: opt: 454, FT E():2.6e-23, (35.7% identity in 336 aa)" FT /gene="SPBC30B4.09c" FT /gene="SPBC27B12.01c" FT /product="putative mitochondrial outer membrane protein" FT /protein_id="CAA20322.1" FT /translation="MIHLPQGSFTQGLIVGQLLTLAIIYVFLRFFLFCSPIPKSVANSP FT KQTGNETPDETPSTPLSNNKKRYKKPLTILEPHILNLLYDVNEHEPESLDWFNVLIAQA FT LIQFRYDACSNDVALRKLETVLNKGAQDKSMVDHIYVRDLSLGDGFPVFSHCRVLPHQH FT NSSQLRAEMLVSLTDNINCTVDTKLLLNFPKPAFATLPLSITVRICKFVGKVSLFTTLI FT IMIYFSPSNGAGQPAYMNLSFDPNFVISLQVSSLVGARSKLQDIPKITQLIESRIRQWF FT TNRCVSPQFQQIAIPNLWPTSAKEGHARSHAPQEESSNED" FT misc_feature complement(22552..22568) FT /note="ctaactaattcccacag, splice branch and acceptor" FT misc_feature complement(22590..22595) FT /note="gtaagt, splice donor sequence" FT misc_feature 22724..25282 FT /note="nominal overlap with SPBC27B12 EM:AL021766 S. pombe FT chromosome 2" FT misc_feature complement(22805..22820) FT /note="ctaacatttgtcctag, splice branch and acceptor" FT misc_feature complement(22938..22943) FT /note="gtatat, splice donor sequence" FT conflict 23776..23787 FT /note="12 Ts in SPBC27B12 and SPAB4539, but only 11 in FT SPAC30B4, we have altered c30B4 to agree with the consensus FT to allow contiguation" FT /citation=[1] FT misc_feature 24249..24578 FT /note="CDS SPBC27B12.02 completely contained in c27B12" FT CDS 24249..24578 FT /db_xref="SPTREMBL:O42995" FT /note="SPBC30B4.09, 109aa" FT /product="very hypothetical protein" FT /gene="SPBC30B4.10" FT /gene="SPBC27B12.02" FT /protein_id="CAB63198.1" FT /translation="MPLEKARAIEIAFDNVFHNTKIPDNLQQFDAILKRLERRRFIPTE FT NQKPRVYETELLVLRFREFGVKDNHNHPINLHSLRSKSLIRAQGKKLDLHNRVFLRRNV FT RAVKM" FT misc_feature complement(24984..25282) FT /note="see SPBC27B12.03C for complete CDS" XX SQ Sequence 25282 BP; 8117 A; 4425 C; 4729 G; 8011 T; 0 other; tagttcaaat ttgtgacacg caatatcttt ctcgaataat cctgactgtc agccaaagat 60 tcacttgatt tgcgattcat catggcagga tccaagcgag aatctaattc actagcatag 120 gagggatatt ttccttcatt tgccgagtcg ctcattctaa ttttgaatct cctgaaatag 180 aagtatagga aaatgcacaa tgccattacc acggcgaatg ccacacaacc gataacaata 240 cccacaatag cacctgcatt caaggacgta tggtttgacg ccttgcttgc atttagagcg 300 agggcagccg tactgcttgg aacttcacta ctggttgaag aagaggaact gcttggtgtt 360 actgtgacag tagaaataaa agtagatgag gacatggtcg tgataaacga cgaagacgaa 420 gatggccgac tagaagatga agaggaagat gagcttgaag atgaagaaga atgagaagaa 480 ctggtggaag acgttattgg tacggaagag gaagaactag aagacgaaga gctggaagaa 540 gacgaagaag acgaagacga agaggaagag gaagaggaag aggaagatga ggaagaagaa 600 gaagaagaag acgaagaaga agaggaagac gacgaagacg aagaagaaga agaagaagaa 660 ggagatgttg ttgttgtagt tgaagatgag cttggagatg atgatgaaga cgaagaggtc 720 gtagacgaca ctgacgagct agaaaccgtg gtttgcaaaa ccccattgcc agtcagataa 780 accgaccagt acagatcacc accacacata agagaaccat aacctggaca aggcgttgtg 840 caaagagaac ttgaaacttc tgtagcagta agtgtactac cgcaataaca ttgattatta 900 cggatagcta caaatgctat attatcagat ccaccacaaa tgttgttata gcaatacgct 960 ggatcaagat aggtaaacgt gccttgttca gttaagctac tatccacgag ataacagcca 1020 tattgagtgt tcatgtcagc cgccaccaac cgagtagaaa ttatcaaaag gtaaacaaaa 1080 aatagtaacc tccccttaaa gggagaggaa tttaaaaaga ccatggaaat taaatcgtgc 1140 gtaagtataa taggaatgaa aattaaaact taaatttggt aataaaaatt ttgccctcag 1200 taaattaagt tgttttgtct atagactaaa gagaaaacaa attattggac cagttaagag 1260 aaatattatc aaaaggcgca aaccgaatga aagaaaagaa agattgggta aataaaataa 1320 agagcgtaaa aattcaaatg ccaatgaaga aaataattgt tgcaaaatca cttctttatc 1380 aacatgaaaa agaaaacaat aaaggataaa ggctcagcaa cgcaaaatca agaattatta 1440 agaccgagca gttggtgaaa agtactcaat atccaacttc gtttgttccg aaattaaaaa 1500 cagaatttaa aaaaagaacg aataaaaagt aaagagtaaa gattaattca gaattaaaaa 1560 agaacgcgaa ttcctgaagt tcaacaaaat actcggggac gaaagtacaa acccgtaccg 1620 aacttggcta tccacagagc ttccgtttga atcgtttctt cgagcttccc aggcttgaaa 1680 actcctttac tttaaacaat acactagttc cttaataagg atacagtgtt tgacagattg 1740 tcgtcaaaaa acacttaaga attcgattag ttgttaagtg gaaaagttag ctccgacggg 1800 ccccataaag gctgaagtca gtcgaaccta ggcgaacact attgaccctt accgaaacgg 1860 tatttttgcc ttatactatt taacgaatga aaaaggctcc gattgatact tggttgaaac 1920 tgcgaatagt gcgatgttgg gtatcactat tgaccgatat tgcctgttaa aatgacctaa 1980 acgttacttt acataactcc ttatactgta ttacacgtgt tatatattaa acgctaactg 2040 attttacgat tatcttcttt aaatagcaat aataactctg tacactgcga tatcaccgtt 2100 ttgtagaact tctttagctg cagtatgccc atagcagcaa cttacatatt caattgctcc 2160 tgtagtgaga ataattattc tgtctattta aatgaagttt atatcttaaa ataaaagata 2220 gttatctttc tggatttccg gtttatctct tgaatggaaa gacaccatgt cgaagtaccc 2280 acggttaatt ttttacttca catcaatatg tacaaatcgc taatttgaat atgatgctta 2340 acctagaata gtatatattt atatatatat atatataaat tggagtatta tctcaagtaa 2400 ataagacaca gctgattagt ttctcggttt gaccagtcac cctggttttc taacctaaac 2460 cacttctgct aactttaaca atagcacgta aactatcttt ggaaccttca ttttcgggat 2520 gaccaagtcc tttacctgca taccatccta acttttcgag caaccgacga cctggatttt 2580 ctttgctaat ttcaggggca tcttctccaa caatttggcc atcatataca cgtgtggctt 2640 tactcgacct cacagaggaa acagtcattc gagatttcct accagatttg gaaaatgact 2700 gatactcaac cctggtctgt aaacgctcca taatcctggt aagtgaaacc aaatccacac 2760 tagatgcatc aaatttatga gttttggaaa gcatagtata ccgcttgttt ccagatccat 2820 aacttctcga cttcaagttc aaatcgttgg caagcgcatg aaccaatcga cgaacatatt 2880 ttctgcatgg aggaagggaa atttcttcaa tggccgagtg cttaaactgt tgcatccgtt 2940 gataaacatc atttataaat atcttatcaa ttcgtgtaag actagcattg tcagaatcgg 3000 aagaagacgg cttctggctt tcgcgcaaaa gtttcttttt gcttttcttt ccaagtagcc 3060 cctcagagcg gagtttctcc ctttccgctc gtcttcttgc ctttttgctt ttatctttaa 3120 gccattgttc ttgcaattca gcgtacaagt tcatgctctc atcgtccaaa gaattggaaa 3180 aggcatctcc cattctagcg gccacagcct ttcctgcctt tctctctaat ttcttttgag 3240 ctttacgcat ttttttagga agtttgcgat cttttttcaa acctttttct tcttttacct 3300 tcgccccttt tttgctttga gaaacttttt ccgttttttg agttgagggg ttattgtact 3360 cttcatcctc actgtcataa tcataaatag taaaatcatt ttgcaaagta tctccaatac 3420 taaggtatgc ctcaatctcg gaatcatcac tagcatcaaa aattgccaaa agctcttctt 3480 catcttcatc ttcatcttct tccaaaatat catcttcatc ttcggctaat gaatctgtat 3540 ttcccacaag ttccgtcgtt aacttagcat aatcatagtc atctgatccc tcatcaaatt 3600 ctaaagattc cgaatcttca agtgaaaaat ttactttacc ctctgtctca tcgtaatttg 3660 atatttcagg tttttctttc tcctcttcct cctcttcttt ctctccttct agctcttcat 3720 cttcgtcctc atcatcatca tcttcttcta aaacggagag gtcggcaaac ttgttcatag 3780 taaacgtagt cattttatcg gtggtgtcat caatatcaaa ctcgtcttca ttttcggtac 3840 tcaactgctc ctgtgcctga gccaaaggcg gtggaggtgc agcgttattg ttagcaatat 3900 catcattgac caagtttgga acatttagta tgtctaaaga gtcatcatta tctttagaat 3960 ataactcctt ctcagattct tgttctttgt aacacaactg ctcactttct tctgtagatg 4020 aaatttcctt atcacttggt gcaagattta aagaatgctg aatcaaaaca ttttcgttca 4080 tgcttttctc aggaaaactt gaaacttcta cattcttggt ggtatcaaac gcttccgcat 4140 attccggaat tttctttact ttcaatgtat cacctttcga agtaattgct ttaaataaca 4200 caatgtccaa cgcctttatt tcaccggttt ttgataaatc ttcgcaggac ttaacgttgg 4260 tttccttggg aagcataatc tctttgcttt ggtgcttagc ttcattgtgg gcattttgtt 4320 catcgattaa ttgacacaat tcttccgccg ggttgtaatt gtccttagca cgtataaagg 4380 taattcgggg ccattgtgaa attcgactac tagggtttaa accaaaaggg cttttagaat 4440 tattggatcc cttaaatctt cggattcgtg tatcaccacg aaacctggca gaagtttgta 4500 actgatctaa aatctgtaga tcatcaaaat ttgacattga gggatacaag tcaaaaaata 4560 tgataaaaaa aataatatat aattgtttta ataaataatg atggtgaaat cctaaattgt 4620 gaggtgcgta aaccaaatgg tggtagtagg atggagtctt gggggaaagt gcttcatata 4680 gtacactaaa cgattttgcc acggtattaa atacaaattt ctaaatattc aatttacaat 4740 ttaactatta atttcaagta tacacgtcta tttaaactga agttgaggag attcatacat 4800 tgaccgactc aaagttgaat atgaattaac cgacagtagc tcatcatgta attataagtt 4860 ataaattttt gtataaaaca tataaaacag ccaaataact ataatgtaaa tagtgcaaga 4920 aatagaatgt tagaatatag aacgctatac taatgcagtt tcttttacgt ccctcgagag 4980 caacgacagg ggaaacgatt tgttcttgaa acagggagca atgtaaaaat acatagaatt 5040 actttataat gaaaaaaatt cctttttatt ttaaaagtat aaaagagaag cgtcgaatag 5100 ggaacgagat gacaaattct gcatatgatg agaacggtaa ggaatttgaa gttgaacaca 5160 tacacaaaag tgtattcaga aaaaggaata aataatgtaa tacgctcaaa aaaaagaaag 5220 taatagaaat ttttcttaag aatttcaaac ttagacaacg aaaaataaca gtgagtgcag 5280 atatatgtat aagtagcgag cgaaccgaat attaaataca aaaaaacagc tataccttgg 5340 tacgtttttg agcgttcagc atatcagaag aatagaagtt aggattattg ttgggatttt 5400 caccttcaac cattggggaa tgggtacctt ggcgtttaat cccctgaaga ctatagggcg 5460 gaacagaggc aatcggcatg gattgaggaa gaattgatgg atccatattg gggatattat 5520 tttggtccaa aagacgatta gcttgactaa ttgcattagc aggcatagtg ggaggttgct 5580 tggcataacg ataattagag gcaagactag caacatcacc attcctaggc gagccattaa 5640 accccgaggg ggctggattt gcatatggaa tattagagga agtagacttt tgcatttgat 5700 gctgttgttg taaagctgta gcaaatttat gtaaagcgct agtcggaccc gatcgctgag 5760 caagagtgaa ggctatgaga tcgcgcattc ccgaaattgt ttcagtaatt tccatgaacc 5820 gcatgatgtg cggttccaat ccatattcgt tgacgggtga atccggcaaa agagaagaag 5880 atgagttaat atttacactt tcggatgacg gatcctcact ttttacccca tcgtgttgta 5940 tttgattttg aggaggccgc gactgcgaaa gggctaggga agcgtttgtc attaactcgc 6000 gcaaaagata ctcggaatgt ccgacagctg aaaactctaa agagtctaat tttaacaaag 6060 gagcacgaaa gaaatgagcc cgcaagtgcc ccgatacaat tacctgtaca ccgccttgat 6120 actgatataa aatgcttgcc cttgacgatt ccacaaaata cccattgttt ggaatggcaa 6180 attcctttgt atttcccaaa aggaacgaca tctttttaag tttgccgcaa taactcagat 6240 ataagaagcg cggaagtgct gcatacgata attcaaacaa tttcggctcc tggtttggcg 6300 aatctttgta gtcgatgtta tagcgaaatg ttcccttttc agtataaaaa tcatgcacaa 6360 atcgtctcca atacccaata tcatctttca tggtactttc ccatcctgac attaactgtt 6420 cattatattg taataatcgc aaaacaccgt atcctagtat attcgagcca ttatgataca 6480 tcatggacgc atagtttgca accatagctg cgaaatttac aagaaagcca ccagcgctgc 6540 agaattggat ttgttcaaag tgcaaagcgc ttgtgaaaca ttaacggccg gagcccgcca 6600 tgcatggtta accctttaag tgaattagag attggcacgc tacgttaaag acatttagaa 6660 aatgtgatgc gctgtgttat tacaaacggc ttgtatttgg gtgaagatag catctttcaa 6720 acgcctgaat ttgtgatata aattaacatt ttacaaatta aaatatagaa taaaaaattc 6780 cttcgtaatt taccttgttc ccatttttta cactgatttc gagtatcaat attaatgaga 6840 tcaacgccag ttttccgtat gccctttatc aatgttctct tattttgttt taaacaccac 6900 ctttcaattc gatatattaa aaagaatgaa aaatgtatgt gagagtatgt caagataact 6960 tgcaaagtaa gagtcagcag attaataaat agaaaataat atttaaaaag atttaggaat 7020 gtcttggttt gattatttta atatgttgta aggttccttt ccgaatgtat acaagcaatc 7080 gtagtttaca gatcacaaaa tcggtaattt attttcagtg tctctataca ttattactta 7140 tttgatgatt agttcttgaa tttgaagatc atcaaaatca ttgcccttac taaatattgt 7200 tgaaataaaa attttgcatc ggtattaagt tttgtgtttg tatacctcga aatcaaccaa 7260 aaaaaatttt ttaaatggtg tcgcatagtg taatgtttat aaattaagta aaaaaggctt 7320 gatttcagga aagatttgat atagttgatg tatctcgaat tactttattt tgaaaaaaag 7380 caatgaatgc gatattgcaa gagaaatcat tcatcaaaat tttttcgtta tacagaacaa 7440 cagcacagtt agtatttctt gataatactg attacaatta atatggtttt ttttagaact 7500 aaaattgatt actaattcat tctttggtct aatttctata tcgtttttcg aaaattacta 7560 ctccattaat gtttctctag ctgttttatt tacttacttt aaatatttct cactatagca 7620 cgtgagtgta acgaggtaac aaaattgact atatgaaacg agagttagtt tcaaagaaaa 7680 ggaaaagcag gtaattcttt tacggtcatt tatcattgat tttttaggta taaaaaaatt 7740 ttgtgtcgaa gagttgtgaa atttttaata gattactcaa cacatgattt tctagatgag 7800 aactgtaaag tgtgttcttg gttgtgaaaa gaaaacatat aacgatgaat aaagaaaaat 7860 aaaaatctcg ctgtcctatt taatgtactt ccatttttcg cgttttaata tgttataaac 7920 acatatcgaa tttaaaagtg ttgtagagtt gttttgttat agtttgttac attactccaa 7980 cttgctactt tctaaaacgt tctgtccata taccgtactg caaacctcac caccgtaatg 8040 cgcaaaagtg catatttgga cacaagcgat gtcaacggtt gctacacact tcttccccaa 8100 ccactcacat ccttccagaa atttgaggat gaagcagggt tagggtttta aaaggtatat 8160 ataccgatca gacgccttca taagccaacg ttctacttcc atgagtctga aggagccaca 8220 tcaaattaat atgctaggac gccaaagtag tggagacaag aggtttattg attgattatc 8280 tgatgttgaa aggcttaggt tcttatcgta aatggcttgt attttgtgtg ttacatttat 8340 tgatattagg atggttctcc ttcaggctct tggaaagcgt tcgcctgtat ctgtgttgta 8400 ttttttggag agattctagt ctgattctag tcgtttgatt gtacagtatg tctgtcgtgt 8460 atggttgctt tattgttttt ctgggattaa gtcatcttgg tgcagtaatt ggtactgtgt 8520 tggtagaaaa acctaccata ttcctttttg cgcttgctgt ggtatctttt tgactatagt 8580 ttgagattaa ctgggtgtta aagcttagta gggggtaaat cccgtacgca tactgaaacc 8640 ttgaactcaa actgaatctt tgtcgttctt taagtgcctt gttaaacttg tttgtaaagg 8700 tatgttcgcc gtatgctgat tgatgtctga gtacaacgaa gctgttctga tgatattatt 8760 atgtcttctt tacccgtcct atcgactatg acgataactt tgtctccact ataggtggag 8820 accatacttg ccagtatctt cgatgtctga attgttttcg ttgttccagt atcttagtaa 8880 tctctgtatt gtgtataatc tttcagtgta ctaacttctt ttttaggtgt atttgtgcga 8940 aactttcaaa tttcttgcta tgcttaaact cgcgaactaa acgtgtatgt tctgtatggt 9000 gaaaataatg tgtgtttttc gtgtagctac tcctgtacgt acgagttatg gtggagattg 9060 gactttacat ccttttagtt ataaacatat atagtgctgt attgcttttt ggattgttcg 9120 gcgaaggttt ttttttgcat tgatcaacag gtgatgaaat ttccattgaa cattcgcagt 9180 ttccccggag cggcatacga acccaatttt gccgcagatg tcgtgcatag tccttccttt 9240 ggatgtctga tgttgatctt gcaaattttt cctttttttt tttttaatta aatttttttg 9300 tgttgtgttt ggcttgtagt tgtagtggtg ataaaggttg attatcatgt tctccaatat 9360 agagtagtta aactttttct tgttgtgatg gaaattgtag tctggttgat ttattgaatt 9420 cagtctattt agaattgctt gaaaatactc ttaataaaat tgttgcaatg cgtagaatgg 9480 caattaactc tacataggtt aagtagtctt tctataaagt aaataaatca tctctaaaaa 9540 tttgaaagca tgtttagaca atatacatac agaaacgcat cagattaact agaatgaaga 9600 caaaaatatt aaacgtttgg aaaattatct acaaattaaa tgccagattt atcatccgta 9660 ttttctaaag acgcatcact gtccccagtt cgatccaata aatttgagat ctcttttaga 9720 aacgaggttt ctgttgtagg agccagcaaa acagcgagga gagtttcact tttggggaaa 9780 gaagataatg aaatatttcc agcttccact aagctcaaaa gtcgacgcac cgtagatatg 9840 ccactctgaa tcacataacg aaaaggattc gtagtaggat actgcgatgc tacacgtgat 9900 ggtggattaa gggaaggatg acctgataat agtatgagta ggcgtaacat ggaaacaaaa 9960 aatccctcgc ctatattaca ccaatttgcc gcttgttccg attgtttaac ataggaaacg 10020 gtagctgcta aacaaaaaaa tgactgctgc aataagggta accttcgctc gcatatttta 10080 aggcagtggc ggttaaattt tgggacaaca gaagcaagaa gtagaaaaag ggagtctaaa 10140 aattttggat tgttatcaaa aatagcttga aagtttgtct tgttgttagc atctttggct 10200 agtaatttgg cataggcatt aatggcggga ccagcatagg gatgggtagc aggtgtgtaa 10260 ctaggtatag aggttggaag ggtgtcattt aaaatagttt tactcttctt tctgttaaat 10320 ggagaaaaag acaaaataaa tagtaaaacg tgacgagcaa cgtcgacatt cggtagaatg 10380 aaattttgag aaagttgaca aagtacgatt aatacatctt tatgcaaatc caaggtattt 10440 cttgatgaac gtagaaggga agtggcatga aaattaagac ttttgactac acgaatgagt 10500 agaggaaaaa aatctggatt ttgtaccaaa acgttttggt tggcctcaaa gtgagagaga 10560 tttctaaaaa taacgaaaac agctaacaaa ttttgctccg aattatgaac atcaatagca 10620 ttgatgctat cttttgtttt gttttcgctt agtgaatttg aaaagtcttc tctggagaac 10680 tgcgatatct ctacgcaaca attgtaaaga agttgtctat aagaaggacg tttatcggcg 10740 atttccatta aatcctcatt aggaagaaca gatagcagat tatcaaggca ctgagttgca 10800 acgtcaatca acgcatcaac tacatcctgg cactcactta acggaaacat ccatttttga 10860 tcatttgtta atataagtaa aacgttcatt gcatacgtta tttctttttc caaagtagat 10920 tgcaggctca tgcacaaggc ttgaatgttt acagtcccca gatctacgat tgaaggcatc 10980 tgaagccgaa gcaaagattc atcgagccta tacgtggccg cgacattcaa gggataaccc 11040 aacataggat cgatgggctt ttttatcggt tgataagcaa cgggttcggc agaatcaaca 11100 ggagctgccg aagaagaagt ttgaacggtg ggcggagtgg gtcgagtcgg agcagaaggg 11160 tatggtggag catttctttc agaactaact gtggtaggag cagctggaga gaaacgatta 11220 gcggtgaatg ctggggaggg tgactttgag tgaagtgatc catgcataga accattggca 11280 tgtacagctt ctggggtggt ttggaccggc ttttgtggat agttttttgg tctgctttga 11340 acattcgcag aatgattagc ttttgcttgt tgaagtgatt tttgttgctg ttgagcagca 11400 agccatgctt cttcatatgg aagcagatag gaattgtaat attgaattag aagggaaata 11460 gcatcaggag atggaaaccc caaggaagca gaaatttttg gccaaaaatt atgagctgag 11520 acttgtcgag atccaccggc acgcataacc aaggcgtaca gcatcattaa attaataggc 11580 gtattattta tttgaggata agatttgatt ggcgtccccc gcttttccat aaaagaaata 11640 aggctaacca tgaatttgtc aaaactagca gcataagcag gcgttagttg attagcatta 11700 ccagagggag tatttgggga aggtgcaggt tgaggagttt gtcttacagc tgggtgggca 11760 ttgatgccaa tttgattagg aggaatttgt tgagagagta aggcctctct gctttgcatt 11820 tgtcgttgat aaagttgttg ctgctgttgc tgttgttgtt gctgctgcat tgcagcctct 11880 ttttcttgtt gaaacgggat ccgacttgaa ggcatcatgg gactagagta tttcacagat 11940 ccagagccat tccatgcacc gttagaggcg aaatcaaatg attgatttgg caaattacgt 12000 tgagttgatg gagattgtcg gaagggctgt gaatgagcca aattgttagg ctcattctcg 12060 gaagtattca tcatgtttgc atttccatat tctgctgcat acatcccttg gcttgtcgaa 12120 aagcgttgag gatacgcagg ttgttcttcc tgagtattat aactttgacc ttgcgtggga 12180 tatgatactg cggttggata atcactcgca ggaacaaacc cttgattatt catgattcct 12240 catactaaat caaacaaaga gtaaagggac cttaaaatac acgtttcaat atattaacgt 12300 ctaaggcgct tggcagctga aagtgcttga aaagcagacg aagtgcatat aacgagttgt 12360 ttagtgctgc ctttaagaac ctaatctgtg tgtttcagaa aatgcttaaa ttcctaaaaa 12420 atctttacac tcattccttt aaatctcgca aacgtgattt cttgcctttg cagtgtctct 12480 tatttccaag tcaatgacaa ttgttagcat tgggaagcat ttatcgatta gtcaggtatc 12540 taaaatttta aaaacaaaat aatatcttat tcctcttgta atagaaacaa tatttattaa 12600 cttgctctgt tagtagactt ggcgaaactg taaacaatca cgagtacaac atcttcttct 12660 tgcggaaaca gatatttttt taataaatta tttttttttt ttttaaaata gtaaaagcat 12720 atgagttaac atattcgaga tcccgttatc ctccttttct ttcttttttt tttttttttt 12780 tttttgaaag gagcaatcaa aattgacaca ttaattcaaa tttatctggt ctaacctttt 12840 ttttattttt tattcattat ttttccttct ttctttctgg ctacataaga ctcgacgcaa 12900 tgtcatttta taaatttcat tgttttctat aaacgtgctt tcatatgtgt aaacctattg 12960 atgaatgaaa caagatagta gaatatggta atttctatta tcaagcaatt ggatttaggt 13020 tgttgaactc tatggacaag ggcttgtacg tgtaaaatat atatgtttat gacttaatta 13080 tttacttttg caaatctatg gtttcaagtc aactcgcaaa aggaatatcc gattcaagaa 13140 ggaaaaaaac taaatactac aataaaaaaa ggtttgtagt atttgagata aagatggaga 13200 tgctatattg cacatgtaga atttgatggc ataaacaaga attagatttg aaacaaaagt 13260 caactaacac aactttcaag tccacgtata aagcgatttc tattctgacg gttcataaaa 13320 tgtttaatga gcttgcaaac taaaaccaag taattcggaa attaggtatt tacaagctga 13380 taattaaaat gtgaaccctt gaattattga taatgaatta tagattttat tagttttaat 13440 tcctttttta agtaatttat caagtatagt ccaactattt atttacaaat attggtatat 13500 tagggtgttt taatagaaaa aaaaacaaaa attaagcgaa gaaaagtatt acattaacaa 13560 gcctgaaaaa gaagcaaaca aactaattaa aagatgttaa ctatatcaaa cttaagagaa 13620 aattatttaa taaataaaac cggaattaaa aattctctat aacgatgtta gagaaattgt 13680 tctagttacg tcggtgtcct tcaaaatctg cccttaacca caatccctgt aggaaaacta 13740 tggatgacat tccaactctt cttgcgagaa cattaaaccc tacgacttcc aaaagtggta 13800 agatacccca acagagtgga taaagcaaat ttactaactg atatagctga ggaagcactg 13860 aaagtatggg aattacaaga tagttctttt gcactaaaac tcctcaatat tgtcgctgag 13920 gatacagtag acatcaatat taagctggcc gcttcattgt atttcaaaaa ttacattaaa 13980 aaacattggg attctgagga aggtgcttct attcgtatca gcgatgaggt ggcagaattg 14040 atcaaacgcg aaataatcaa cttgatgctg aaaagtacta ccattattca agttcagcta 14100 ggtgaagtaa ttggttatat tgccaacttt gatttccctg atcggtggga cactcttctc 14160 cccgatctga tatctaaatt gtctgctgtt gacatgaaca cgaatattgc tgtactttct 14220 actgcacatg cgatttttaa gcgctggaga cctttattcc gtagcgatgc actttttttg 14280 gagatcaaat atgtgttgga tcgtttttgc gaaccatttc tcgctctctt cgtgcaaacc 14340 aacaacttat tgcgtaacgg tccacaagat gcagagtctc ttaacagttt atttcaggtt 14400 atccttttgg agtgtaaact tttttatgat ttgaattgcc aagacattcc ggaattcttt 14460 gaagatcata tgagcgaatt catgaccgcc ttcttaaact actttaccta cactaacccc 14520 agcttggagg gtgacgaagg agagacaaat gtccttatta aagttaaagc aagtatttgt 14580 gaaatcgtcg agctatatac ccttcgatac gaagaggtgt ttaccatgtt gtatgacttc 14640 gtcaacgtaa catggacact tttgacaacc ttgactcctg atgaaaaata cgatggttta 14700 gttggtaagg ctatggcatt tttgacatcc gtcattagaa ttcgcaagca tgccgagttt 14760 ttccagcaag accaagtttt acaacaattc attgaactcg tcgttcttcc taatatatgt 14820 ttgcgggaat ctgatgaaga attatttgaa gacgatcctt tagaatatgt ccgccgtgat 14880 cttgaaggtt cgaacagtga ttctcgcgcc agatccgcaa tcgttcttgt tcgtggactt 14940 ttggatcact ttgatcaaaa aattacgagt gtagtctcaa ctcacatcaa tgctaatctt 15000 caacaattct caacaaatcc ttctcttgaa tggaataaaa aatacgtagc gcttcagctc 15060 ttttcggcta ttgctataaa gggtcaatcc acaagactcg gcgttacatc tattaatttg 15120 atggtagacg ttgttgcttt tttcgagaat aatattaagc cggatctttt acaacctgct 15180 ggcgtcattc atcccatggt tcttgccgag gatattaaat atgtatttac atttcgcaac 15240 cagctaaatt cccaacagct tattgacatt ttccctacaa ttttacgctt tttggaaatg 15300 cccagctttg tcgtttacac atacgctgca atagcattag atcagttgct gactgttcgt 15360 cataatcatg ttcatatctt tacaagttta ctaattgctc cacacatatt acccgctcta 15420 aatcaacttt tcctaattgt ggaatctgca tccacaccac aaaaacttgc cgaaaatgat 15480 tatctaatga aagcagtaat gcgaattatt attatgtctc aagaagccat tcttccagct 15540 gctagccttc ttcttcagca cctcacaaaa attacggaag aggttagcaa gaatccttcc 15600 aatccaaaat ttaaccacta tctcttcgaa tctattggtg cacttattcg tagtttatct 15660 aaatctggtc cccaaaccgt ctctcaactg gaaaatgccc tacttccagt ctttcaaaat 15720 gtgcttatag aagatgttac tgagtttatt ccgtatgtcc tacaactgct atctcaatta 15780 gttgaagcta gtggcaatga acctcttcct gactttgttg tcaatctcat acagccgtgt 15840 ttatctccag ctttatggga ttcaaagggt aatatacctg ccttagttcg cctattacgg 15900 gcaatgatat ttcgtggtcc tcagatattt atttccaata agtttgttga accggttttg 15960 ggaattttcc aaaaattgat ttcttcaaag gttaatgatc attttgggtt tgatctcttg 16020 gaccgagttt tcacagtttt caatgctaac atacttgcgc cttatatcaa ccacatattc 16080 tttttgctgt taagcagatt aaaaaactcg aggactgagc gtttcgttct gcgatgcacg 16140 attttcttct tttttgttgc ttctgagcaa acgggtactt gcggcccaga taatttgatc 16200 caaggtgttg atgcagtcca gtctggagta tttggccaat tgatgacttc aattattctt 16260 cctcaagcac aaaaattggc gcttccatta gataggaaaa tcagtgctct tggattactg 16320 cgacttctta cttgtgatct agtactcgcc ccagacgcaa tttatgagaa tcttattatc 16380 ccattattaa cttgtatcct caaattattc gaaatgccta ttgaacaagc tcaaacagat 16440 gcagatgaag aattgtttat ggacgaaatc gatgctgatt cgatgtcatt ccaagcttcc 16500 ttttccagat tggctactac tggcggaaag agggttgatc cattccctca aattactgac 16560 cttaagcagt attgtgctac ggaaatgaat cttgctaaca gaaatatggg tggacgttta 16620 tctcaaatca ttagcacgca tcttcctggc gacggtcaaa gcgtgcttca atcatatggt 16680 tacgtgatct aatatttatg aaatgaaaat catcagaaat caactttctt gatgtttttg 16740 tttaaaaatt tgggtgtaaa tttagaaaat aaatgttttc atagagaagc atttattaaa 16800 aattgtattt ggttgtcaaa tattttttaa atgagattca tatcattatt ttatcctatt 16860 atatagtgaa aattaagtcg agagttataa atttgtagat tggttttctt cgctcgaatg 16920 catatcatac attggcatat atacctttcg taaccatgcc tcttttgctg ggttgtaata 16980 tgtatggcga agtagtcgaa taatagttcc tggtttaatc ccttgaatgc gtttcagttg 17040 accaattgta gctggacgaa tcgtcttcag cagcattaat tcttcagccg aaacagaatg 17100 taaagtatca aaatcaaaat ctgagggtat tactgtagat tcatctctac aattgagttg 17160 tttattttga gtaccttgac gctttatata ataagtatac tttccctcaa ttattaaacg 17220 ttgtagtacc cttttgggaa tgtcctttag tttaggaatg cacgaaataa cacaaaaaag 17280 atccaaattt gtgaagctca acagatccca agcacttcta tatttcccgt cattaggaat 17340 cggcattcct agctttgacc attgctgagg acttaaaatg aactccttgg cgattttatt 17400 ggaaaaatct aacaaagatt tagttctttg aaagctttcc caatgagttt ggtcgtccaa 17460 taaacctata ctttgagcta atggagtcaa tcttaaatca gcattatcag cacgtgtagt 17520 taacctatac tcgcttctcg aagtgaacac cctataaggt tctttcacac cttttgtaat 17580 aagatcatcg accattactc caagcaaagc tgtatttctc ggtatgtcta ctggctcacg 17640 accaagagca cttaaacctg catttaagcc agctaagata ccttgcgctg ctgcttcttc 17700 ataacccgtc gttccattta tttgaccggc caagtacaaa ccctgaattt tttttgtttc 17760 cagtgttgcc tttagttggg tggggataac ataatcatac ataactccat aagctggtct 17820 cacaatatta caattctcca ggcctggaat agaccttatt atattgtgct gaatttcttc 17880 aggcattgag ttactgagac cattgggata ccaccaagaa ttggggtcca atccttccgg 17940 ttccagccaa ataagatgtc ttgctttgtg agggaatctt gtaaccttgg cttccaatga 18000 cgggcaatac cttggagaaa gaatatcacc agcaagcata tggggagcaa aagcgagatt 18060 tttcctaaca atttcatgcg tcaattcagt tgtataagtt ctgtagcaag aacgttgtgg 18120 caatgccggt gaaaaatccc tttccaaatt taaaaaacta aatgtttctg gaatttcgtc 18180 acctgtctgc tctgtcattt ttgatatatt tatgggagag ctcaatctgg gaggtgtacc 18240 tgtttttagt cgacccattt taaaacctaa attgctaaga catttactca aaggcaatga 18300 aggtcgctcg ccatatcgac cagcagctaa ctgtgttaaa ccaacattta tttgtcctcc 18360 taagaaagta ccagtagtaa tgactataca actggcagga atagcagtgc catcttcaag 18420 aacaattgaa tcacaaactt gtttaccatc gtcttctgtc aaaacattaa tagagacggc 18480 cgcgccttct ctaacttgaa gattttttct ataagttgaa atagtttttt gcatattttt 18540 tttgaagacc gaccgatcca tttgtgctct gggactccat acagctggtc cattcgatcg 18600 gttcaacatg tgaaattgaa ttgctgattc atcgcagaca ccactgacaa caccacccaa 18660 ggcatctatt tctcgcatta gtgttccttt tccaatccca ccgaaagctg gattacagct 18720 catttgtcca atattgtcga aggactttgt taaaagagta gttttcgcac ctaatctaga 18780 agcagcagca gcggcttcca cgccagcgtg tccacctcct atcactacga cattcttccg 18840 gcgattgaag gaggtgcaga aatatcgctt tgttgttcga aacatttgtt caccccaaat 18900 aaactatttc aaaaacatac ataaggacct tttgttaaag taccgacaaa aaaatgcaca 18960 aaatatattt gagttatgcg taaaggttaa tgataaattt gttgttgagg tcttgctgaa 19020 ataaaacgct atatagtcgg gaaagagctg ttaaaaagca cagtcaatca aaaattctaa 19080 aattagtgga aaatagacat tcaggatgtc agaagtttgt aattgaatct atcaacagat 19140 taggcaatgg ttgtaatgct cctaaggtta atcagactaa tttacgtctg aaatctgaag 19200 atttagaaca aatatattac aaccttttta ttatttttcc ttttttaaaa actatgaata 19260 tctgattgca gaataaacga atttaagaaa atactttttt tttttcaagc ttgtcgtcac 19320 ttgtgagttt gagaatattc gggcaaataa aagtaaaccg gctctattag tatgaattat 19380 caatccgcgc ttttattgct cagtacagaa attcagaggt tgagttacat gtaaaaacca 19440 agattcgtaa ccttactaca ataatcaaac caattcatta taaattgcat tcatatagat 19500 ctcaatgtaa tataactttt ctgattaaaa aagcttaaaa aaagccattg ttaaaatgat 19560 caagcaccaa cattagagat gcaatagatt ataaacagta gaaaggaaag ttcctgtgaa 19620 ataatttctg tcagcatctt caacattaat gattcgttag taaattaatt aaagaatagt 19680 atataatttc gtcttactgc actgtttgga aaagaaagaa gccaatgcaa cttgaagaaa 19740 taatagaaga agctctaagg aaataaataa taatagggta cgttggaatg aattagttgc 19800 ttatacgtta agtttctact tgtggatgcc ccttaaggaa atagtttgat ccttccgaaa 19860 aatgttaaca tttcaagtgt atcaaaatgc cagaaagtaa aaatcgccaa aaaaaaagag 19920 ctagactgta caaatcacca ggataaggag atttaggtaa tgaaaaacag ggtttcaaat 19980 atgataaagc tgtacacccg gtgtgagaca aagaaatata tagtttaata ataatataac 20040 gaattatcaa gtgtgcaatt tttttgacat aggttctacc gtgaatttgg tatgacaagt 20100 agaacaatgc acccgtggtt cacaaaatac taaagaggtt agcaaaaggt caaatgttca 20160 aagcctatcg taaagctttg ttactactta cttgatagac aaactgagca aacaaagcca 20220 atatccaaaa cctttttgtg gcaaaaacat gtagctcgaa aatcaacatt cgcttggttt 20280 ggggtattta agtgttttcg aagattttga tccggaaaaa gcgacatcat gagatattgt 20340 agtaagcctt tggggttgtc aacttttaag taaatccctc ctgtggcatc tgctgcttgt 20400 tctaaaaaca gggtgcctcc ctcaatgttg caaacgttaa ttggaatatt tttcttttga 20460 gcacaaaata tacaattcat agtaggaata tactgaagag caacatcacc agttaatgag 20520 aaaattagaa ttcgagaacg aagagtattt ttattttgaa cttgattgat atatgcaagg 20580 gctctagata gtgctccgga aatcatcgtt tttcttgaaa ctttatcagt cgaactcatg 20640 agtcgcttca tcccagataa aactaagtcg tctacctcac gaaactttcg atacgtattt 20700 gcctccttgg taggatctac ttctgcgact ttttgctcag gtgcaatcga agggtatagg 20760 tattcaacct tgtccgagtg tgaagctaac acagcaactc tattatcatg atgaaaagct 20820 aagtgtgcgt ttagaaaaac cgtaatatct gccagtacct tggaaacagg cacttttttg 20880 gaaagggagt accatgaggc aggatttgcg tctaatataa ctacaagcaa actgggtgta 20940 tcatttgcgt cttcagatat atcccacgag gcattttgtt tcaaagtttg aaattcatcc 21000 atccctcttt ttataatgtg ttttttctca atgctttccc aactttaata caggtagaca 21060 acaacccaga aaaagtgtag ggttcaaaaa aagattgcca acaaaacagt gttatttcaa 21120 aaacatttat attccattat aatgaaatgg tttatctaat gaaataaaag gtaaagtaat 21180 tccaaaaata taaaaaattt atggagtcgc cagtgcagat tttagtttgg ccttttccat 21240 gtgacgagat gaaccaaaaa acaccgtcta cggtagaaga aattcgtata gcactacaag 21300 aacttgggtt gagtacgaat ggaaacaagt atgttactga aattgagaag caattagtcc 21360 gttttctcag agtttatata aattaattat ttacacagta taaagagaaa aactgaaacg 21420 gcgatggaaa tttcgtgaaa aacgtcttga agaaaaacga aaacaagaac gttatcaaaa 21480 gttttctact agtaatgaaa acaaaacttg tttgtagggt taaatcatca attgtttaaa 21540 cattttctat ctaacagtaa ctgaatactt gtagacgata cttgctaatt gtggacgtcg 21600 aagctacatg tgaagaaggt tgcggattta gcttcgaaaa cgagatcata gaattaccat 21660 gtcttctatt cgatttaata gaaaaatcca taatcgacga atttcattct tacgttcgcc 21720 catccatgaa tcctactttg tctgactatt gtaaatcact gacaggaatt caacaatgca 21780 ctgttgataa agcgcctatc ttctcagatg tcttggaaga actattcata ttcttgcgga 21840 aacattccaa tattttagtt ccctcagttg atgaaattga gattatagaa cccttaaagt 21900 ccgtacccag aacacagccc aaaaattggg cctgggcttg tgatggtcct tgggatatgg 21960 cgtccttttt agccaaacaa gtaagtgtta atataatttt gttcggtttg tctcacattt 22020 cgctaacaaa tcgtattatc agttcaaata tgataaaatg ccaattcctg actggatcaa 22080 aggaccattc gtagatatta ggtctttcta taaagacgtt tatcgcgttc cacgcacaaa 22140 tattaatgga atgctagagc attggggtct tcagtttgag ggaagcgagc atcgcggaat 22200 agatgatgcg aggaatttat cacgaattgt taaaaaaatg tgttcggaaa acgtagaatt 22260 cgaatgcaat aggtggtgga tggaatatga gaagaacggc tggattccga atcgaagtta 22320 cccgccatat ttcgcaagct aatgcttaaa atttttattt cgacttcata atcaatatat 22380 ttcgtggaat ctggtagaga taaattatcg ttaaaattca tagataaaaa aaatttccga 22440 aaattacgtc aaaagaatgt ttaatcttca ttagatgact cctcttgagg tgcatgggac 22500 ctcgcatgtc cttcttttgc agaggttggc cataggttgg gaattgcgat cctgtgggaa 22560 ttagttagta tgaatcaatt catactctca cttactgttg aaactgagga gaaacacaac 22620 gattagtaaa ccattgtcga atccttgatt cgatcaattg tgtaatttta ggaatgtctt 22680 gaagctttga cctagctccc acaagagaac ttacttgtag cgagatcacg aaattggggt 22740 caaatgacaa gttcatatat gcaggctggc ctgcaccatt gcttggggaa aaataaatca 22800 taatctagga caaatgttag aaaagaccgt tattaaaaga cgaaaaaaaa tagtctatcg 22860 tagaatacca ctgtgatacg atttaacact tgatgtttca aacccccggg ggaggggtgt 22920 aaagaatcgt agagactata tactattaag gttgtaaata gacttacctt tccgacaaat 22980 ttacaaatcc taactgtaat ggacaatggt aaggttgcaa acgcaggctt tggaaaatta 23040 agtaaaagct ttgtgtcaac ggtgcaatta atattgtcag tcagagaaac aagcatctcc 23100 gctcgaagct gtgaggaatt atgctgatga ggtagaaccc gacaatgact gaaaaccgga 23160 aatccgtctc caagcgataa atctcgcacg taaatatgat caaccataga cttgtcttga 23220 gcacctttgt tgagaacagt ttcaagtttt ctcagggcaa catcgttgga acatgcatca 23280 tagcgaaact gtatgagagc ttgtgctatt agtacattaa accaatccaa tgattccggc 23340 tcatgttcat taacatcgta aagcagattg agtatatgag gttcaaggat agtaagaggc 23400 tttttgtacc tttttttgtt attacttaaa ggagttgaag gagtctcgtc aggtgtttca 23460 ttccccgttt gttttggaga gtttgctaca gactttggaa ttggactaca aaataaaaag 23520 aaccgcaaaa acacataaat aatggccagt gtcaacaatt gtccaactat tagtccttgt 23580 gtaaaactcc cctgcggcag gtgtatcatt tttgttcata aatatactaa aatacctcga 23640 attcgctaat cccgagaatc aaaaccgtaa acggaaaaat tagtcttcgc tctacaagaa 23700 gagtataaat taaacgtctc aaatacaaga gttaactgct tagtaagttg aggctttctg 23760 taatatatat atatattttt tttttttctt tcttgtaggt ggtctacgta gcatttgcaa 23820 ttacagagtt cattgagcct atttgtttga gtccaaaacc gaaatcaact aattaaacta 23880 atggacttca attaaaaaag attattagta aattcattaa ataacatgat ttgtttgaga 23940 aaagcaacta attatatcaa attattgact ttagatatat aaatccttta tgataatata 24000 tattacatta tgaaattata agagaatatt actttcttgt actcttcaca tgtgtatggc 24060 atgctcatac tcaagggtag gaaatacact agtacgcgtt ttactcttcc aaaaggagta 24120 ttagttaaag tatctttaat aaacgacaat aattagttat tctttctttc gtatattaac 24180 ggactaccta attttcgaaa gtttctccgt ctgtgatatt ttattaaaat gttaagcaaa 24240 tggatttaat gccgttagaa aaagcaagag caattgagat tgcatttgat aatgtgtttc 24300 ataatacaaa aattccggac aatttgcagc aatttgacgc catattgaaa cgactggaaa 24360 gacggagatt tataccaacg gaaaatcaga aaccaagagt gtacgaaaca gagctacttg 24420 tactgcgatt tcgcgaattt ggggtgaaag acaaccataa tcatccaata aatcttcatt 24480 ctcttcggtc aaaaagctta atcagggcac aaggtaaaaa acttgattta cataatcgag 24540 tatttctaag aagaaatgtt agagcagtaa aaatgtgatt agtacctttt atacgataat 24600 tttgatgcat tagtaactta cccaatgtga actttactga actttataca caacttacta 24660 cagaaaagac tcaatcacta catgttacgc atatttttaa agcgttaatt ttctatcaaa 24720 aacaaaactg taagcgttca taacttcttt tcaacccaaa ttcacgttta catgaattaa 24780 agtcataatt cagcaatatt ttccatttta gcaaaaaaaa tcgatatgag tagctttaac 24840 aacacggtga aaaaatacca aaaataataa ttctatataa atcaaatcaa aagcggtttt 24900 atttcagctt ctctctcaaa agacaagcta gaacataaaa caaaagagag gggagtgtat 24960 caaataataa atcttaaagt gaattagtta tccttcttgc tggcataagt gcgatcatct 25020 ttaccctcaa cggtgtattg aactgtctcc ataaagcgaa tgcgctgctc ttgcaatttc 25080 tcattgcgaa gttcggcgtc aaataattct tggtctggtt gacgatatga actgcaaaga 25140 cgatcaaaca aggtgaaaaa ctgaccataa ttgtaattaa agtacatatg gtgagcagcg 25200 tgatgagcag caccatttac gacagcgttg ttagaaaagt atttgccgtc gtggatgagt 25260 acggtccaat aatttactga tc 25282 //