ID SPBC27 standard; DNA; FUN; 10943 BP. XX AC AL353866; XX SV AL353866.1 XX DT 25-APR-2000 (Rel. 63, Created) DT 13-MAR-2002 (Rel. 71, Last updated, Version 2) XX DE S.pombe chromosome II cosmid c27. XX KW coiled-coil protein; conserved hypothetical protein; KW Intron confirmed by mRNA; methionine biosynthesis; KW putative RNA polymerase beta-subunit; recombinational DNA repair; KW similar to yeast YKL052C; sulfate adenylyltransferase; yeast rad50. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-10943 RA Seeger K., Wood V., Harris D., Barrell B.G., Rajandream M.A.; RT ; RL Submitted (25-APR-2000) to the EMBL/GenBank/DDBJ databases. RL Schizosaccharomyces pombe chromosome I sequencing project, Sanger Centre, RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: RL barrell@sanger.ac.uk XX DR GOA; P78937; P78937. DR GOA; Q9P6S4; Q9P6S4. DR SPTREMBL; P79082; P79082. DR SPTREMBL; Q9P6S2; Q9P6S2. DR SPTREMBL; Q9P6S3; Q9P6S3. DR SPTREMBL; Q9P6S5; Q9P6S5. DR SPTREMBL; Q9P6S6; Q9P6S6. DR SWISS-PROT; P78937; MET3_SCHPO. DR SWISS-PROT; Q9P6S4; ME25_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPAC5H10.01c. CC SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c27 is overlapped at its 5' end by cosmid SPD972HB CC EM:D83993, and at its 3' end by cosmid SPBC28F2 EM:AL121795. XX FH Key Location/Qualifiers FH FT source 1..10943 FT /chromosome="II" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c27" FT /map="II" FT misc_feature 1..153 FT /note="nominal overlap with c29B5 S. pombe chromosome 2" FT CDS complement(206..604) FT /db_xref="SPTREMBL:Q9P6S6" FT /note="SPBC27.01c, len:132, SIMILARITY:Merxmuellera davyi., FT O47309, RNA polymerase beta-subunit, (153 aa), fasta FT scores: opt: 129, E():0.13, (27.1% identity in 107 aa)" FT /gene="SPBC27.01c" FT /product="putative RNA polymerase beta-subunit" FT /protein_id="CAB89001.1" FT /translation="MGFDVAGYLQSYSLKDWIRIIVYVGGYMLIRPYLMKLGAKIQERE FT HRKSLLEGEVDGTLDPEMTHGTKPKEHGEFDTDDEEEEENPDAEFRWGYSARRRIRKQR FT EEYFKNQDKSPLDAYADDDEDIEEHLED" FT CDS join(complement(2117..2133),complement(1914..2061), FT complement(1077..1835)) FT /db_xref="SPTREMBL:Q9P6S5" FT /note="SPBC27.02c, len:307, SIMILARITY:Saccharomyces FT cerevisiae, YKF2_YEAST, hypothetical 32.1 kD protein in FT nup120-cse4 intergenic region., (292 aa), fasta scores: FT opt: 201, E():1.8e-05, (27.1% identity in 284 aa)" FT /gene="SPBC27.02c" FT /product="hypothetical protein; similar to S. cerevisiae FT YKL052 C" FT /protein_id="CAB89002.1" FT /translation="MNNLEQLERLEQSITLALYEIDANFSKCHRTVTTKILPIVEKYAK FT NCNTIWDSSKFWKQFFEASANVSLSGVEEPVPVESNPSDQDVMSNSTEADLQLHTKNEH FT LEKRHSFVGKSDFPDAAVQGDNTKNEDFVQSTPKKMDVSLEDISLDDAALTPIPARMQT FT PLRKPENNPHTGRSALLHRVLDTNWQVQVTPREPKNLQSQEVMDIDSSPFVSPSPISMK FT MDMPSLNDRNSSHALSLFAEFEHESYDSINPSGMSPPKTIQFSPHTMGVGSSQQANERS FT LSLQRKLETLNDSNDSFVKEEDSWEL" FT misc_feature complement(1836..1849) FT /note="ctaacagaaaacag, splice branch and acceptor" FT misc_feature complement(1908..1913) FT /note="gtatgt, splice donor sequence" FT misc_feature complement(2062..2077) FT /note="ctaacaaaagaattag, splice branch and acceptor" FT misc_feature complement(2111..2116) FT /note="gtatgc, splice donor sequence" FT CDS 2471..4339 FT /db_xref="GOA:Q9P6S4" FT /db_xref="SWISS-PROT:Q9P6S4" FT /note="SPBC27.03, len:622, SIMILARITY:Saccharomyces FT cerevisiae, YJC0_YEAST, hypothetical 86.1 kD protein in FT pet130-cct3 intergenic region., (771 aa), fasta scores: FT opt: 133, E():0.61, (23.7% identity in 333 aa)" FT /gene="SPBC27.03" FT /gene="meu25" FT /product="meiotic expression upregulated; no apparent FT orthologs" FT /protein_id="CAB89003.1" FT /translation="MSSIFGENIVSDSIVNMELTNPDNTTTMHPIYETNIEKEVQQEFS FT DNVSEKETIDSTKSKISLENIQQEMGALAKKIFHKLGVKATDLGFSNEHDDSQDSLQTL FT APSPSYVPLLKVIGSSEEVNSNLVLTDLETNTDGYDPKFLISVRKFLMGSPNSGFVVKH FT EKRLPDGPRVLALRAISSVDEENRKERLSPDSDPVETESVYVDNGELSNQKVETVEISE FT KEQNDDPAGYSQYLLEFKKSKCQKKVPTLESIEENEGTEPHDNLTFMTDLGTPYYSLGN FT EFERKQILDEYGLLANDENLVIGHTLRAEYCFMFDESDILQLRNYEHTEKELSVLQFKG FT VSSRWDFRCCREERLLRLLLCFDSEHTGQSFIQLNDPENENEKEEQNSISIRELSYFST FT KLISLILPKEAHKQRYIMLSSLAKTREADFFWSEEEKTNYTNELLSNPCKFLCELDHFD FT SFPHQQQDLLWKYLAEFSASLELDPNLALWKKQVIFSKIGHPKLLVMPISSFHCVQRFP FT DLVCVQTSTAETFLSVDRELTTYDLNTIKLLNTAPSRTAQNWLFIMHHLEIVGYLFPHL FT VHLDKQYSLLDYAKSVEHIPELGTVQRKGFLNKVAFDDNEALLYQV" FT CDS 4972..8130 FT /db_xref="SPTREMBL:Q9P6S3" FT /note="SPBC27.04, len:1052, SIMILARITY:Schizosaccharomyces FT pombe, P78941, fission yeast DNA for isp4, peptidyl-prolyl FT cis-trans isomerase, atf1,chromosome ii cosmid 1228 FT sequence., (188 aa), fasta scores: opt: 1047, E():0, (89.1% FT identity in 184 aa)" FT /gene="SPBC27.04" FT /product="predicted coiled-coil protein; similar to S. FT cerevisiae RAD50; possibly involved in recombinational DNA FT repair" FT /protein_id="CAB89004.1" FT /translation="MGFHGCLSTDEYEPELIEKYGNPEPPSSSILINTRPVNPFLSTFV FT YVGKASSSEDVSISTGEEEMRTLLVASAVKDAKGWVYLSGKDVEEIKQKIKNLQGLLGV FT SIKKLAVEAKIREAAKNLMVAQAKEKKGKHKQSTIEHYEQCSRRVRELSSKIWLIERKL FT AEFYMHLLKHMVAVCIAELKPGSCSKVSSPVSAITADESATGFRDEEIMNNEEIEQLVE FT RMSRILEIAQSMGNSIREPSVLDAVQMNAGERLLEQVRHLELILKQIYEKKLEEDADAK FT DIAPRAIVNFWRLLTELFRGDNDTPEKSNALPDDELDKHLKSDFDIESFCFLLHHLLSL FT YQTQKKELASSNELLASVRDENTKKLKELQDIIEEQSKHMARLHREGFSEAAENNDKPK FT ETMPCTYDSSLADDHSDTSNLSKDKANTLCAQCSVYLSEKYQQQQSLLQLESNIQQLEN FT EKKAAKLIEKDLLSQISHVKLQFEQQIKAHHYAKDQVRNLNDEMVALRAELEVVKAMNS FT QPDDPDSDYAIKQNNALQNRLEALTRENELLQSRVTTLEMEKEVQEKNSATVSNLTLKQ FT LQMENIFASLNLENSFDFGMPLMGPYTQQNLQLEDEISEISSPSYSSDDDRKTISETQP FT APKQNINEEFENSTSTDGSETNKNEQGNSLSTPDNEPRLRKESLSSDVLLDGSEKPAQA FT ELTINSENFPVDCSLPVQTGADVVVPDTTDEEVITSEPVKLEQPINENSNVEEAEKDYQ FT PSEKDDKSLIGGILSTVEMTQSTDVNDEIENTLTIPVEVEHSDNIDKGSEENDLGKEAV FT DEANNNQNDVLESVVVEQSTTTDDCENKVYEGQMNDKNSSLDMVNACEGINQTAIGFVE FT KPDKVTELIDEAEENIDISQDISMTETNAVDDEVQAENSILQDEVEETRQDDIEKDELE FT DIKEVKEDENLTTLEETIEIPANDIEVQDPEQCSCMNSTENDNITTENSSEIVQVIHTE FT DDSLHFDDNVSTDSVSLGNKSRISMDSMRNDCEAFLPKKEKFGSLRTLHSFESSMRRVS FT TSAA" FT CDS 8315..8641 FT /db_xref="SPTREMBL:Q9P6S2" FT /note="SPBC27.05, len:107" FT /gene="SPBC27.05" FT /product="hypothetical protein; sequence orphan; has FT transcript profile on microarray but this could be FT generated by SPBC27.04 proximal and has the same FT expression pattern" FT /protein_id="CAB89005.1" FT /translation="MVHTTVYGLAYLFYSGINCILLYQLEIESKFYIRYQLIMRVQKET FT TDAFTLQLASKEVITSSIYNTFNNTNEHMYLQPICNRIFLMTSIIDIASFKAQVLFLNI FT FMIK" FT CDS join(complement(9388..9421),complement(9016..9344)) FT /db_xref="SPTREMBL:P79082" FT /note="SPBC27.06c, len:120, SIMILARITY:Saccharomyces FT cerevisiae, Q02889, lpg10p., (113 aa), fasta scores: opt: FT 282, E():1.8e-12, (58.0% identity in 69 aa)" FT /gene="SPBC27.06c" FT /product="conserved protein; similar to S. cerevisiae FT LPG10" FT /protein_id="CAB89006.1" FT /translation="MQSMQPSTVDKLKMGAIMGSAAGLGIGFLFGGVAVLRYGPGPRGF FT LRTLGQYMLTSAATFGFFMSIGSVIRNEDIPLIQQSGSHWNQRLLNENANSSRIFALAM FT QQAKSSPRKSNEVAEC" FT misc_feature complement(9345..9358) FT /note="ttaacactgaacag, splice branch and acceptor" FT intron complement(9345..9387) FT /note="Intron confirmed by mRNA" FT misc_feature complement(9382..9387) FT /note="gtaagt, splice donor sequence" FT CDS complement(10054..>10943) FT /codon_start=3 FT /db_xref="GOA:P78937" FT /db_xref="SWISS-PROT:P78937" FT /note="SPBC27.08c, SIMILARITY:Penicillium chrysogenum., FT MET3_PENCH, sulfate adenylyltransferase, (572 aa), fasta FT scores: opt: 1072, E():0, (61.2% identity in 286 aa)" FT /gene="SPBC27.08c" FT /gene="SPBC28F2.01c" FT /product="sulfate adenylyltransferase; methionine FT biosynthesis" FT /EC_number="2.7.7.4" FT /protein_id="CAB89007.1" FT /translation="NPMHRAHRELTVRAAKQHGARVLIHPVVGMTKPGDIDHFTRVRVY FT EAILQRYPKGSAKLSLLPLAMRMAGPREALWHAIIRKNYGASHFIIGRDHAGPGKNSQG FT EDFYGPYDAQYLVEQYAQEIGITIVPFQMMTYLPDEDIYKPVDKVEPGTRTLNISGTEL FT RRRLRVGANIPEWFSYPEVVAILRQSYPPKYSQGFVLAVPATSDKLLPSALVSALNEDG FT RRHVTLLPRLDAISVFYAQELQRAGAAVVVSLADADASVKVPAEWTTVNIKPKDSVSEV FT TFAVLSQLSDEGYL" FT misc_feature complement(10360..10941) FT /note="Match to PF01747 ATP-sulfurylase, ATP-sulfurylase FT Score 226.78" FT misc_feature 10830..10943 FT /note="Nominal overlap with SPBC28F2 AL121795 S.pombe FT chromosome II cosmid c28F2" XX SQ Sequence 10943 BP; 3651 A; 1938 C; 2125 G; 3229 T; 0 other; gatctcgtag gaaaagaatg cactctcaaa ttgcattatt aatcctacat tcaattaatt 60 agcttttgct ttcatccatg cagtcacggt ttcaagagaa aaggatatca aattttcaca 120 aagaaattaa aacaatgatt aacaaactaa atgacacaag ttttctaaag tgcttggagt 180 aatgaatatt atctcacaac tagaattaat cctcaaggtg ctcttcgatg tcttcatcat 240 catcagcgta agcatcaaga ggagatttgt cttgattctt aaagtattct tcacgttgtt 300 tgcgaatacg gcggcgtgct gaataacccc aacggaattc ggcatcagga ttttcttctt 360 cttcctcatc atccgtgtca aattctccat gttctttggg cttcgtgcca tgcgtcattt 420 ccggatctaa agtaccatct acttcgcctt ctaataaaga ttttctatgt tctctctcct 480 gtatcttggc tcccaacttc atcaaatatg gccggattaa catatatcct ccaacatata 540 cgataattcg aatccagtcc ttcaatgaat atgattgtaa atagcctgca acgtcaaacc 600 ccattttcct tgcacaaaaa agagtggtgg atactaagtt cacctgtctg ctcaaccagg 660 caaactatta ttaaccaagt cactaaaatt ctttagactt ttttagaatt tttaaaacct 720 cgttattcgt cttaacgtat attctcaatg atatgctgta aaaagattta ttaattaggc 780 tataatacta atttatttaa aaattttata gttatttgct ttcttagttt attttaaaat 840 tattttcata caaattttac ttggtttaca gtatttatac cgtgacttat gattctctta 900 aaagaagaat tttccaaatt aaatagaacg tacagtaaat aaaaaattat ataacataaa 960 tataaggtgg gattttatga agtagacata tgtgcttaga aaataaatag aaaaaatgcg 1020 aaagtaaggt tcactactaa aggcgaaacg aaggtgataa cttcagcagt gctttatcag 1080 agttcccaac tatcttcttc tttgacaaaa ctatcattag aatcattcaa ggtttctaat 1140 ttcctctgca aagacaggct tcgctcgttg gcttgctgag aagaacccac ccccatggta 1200 tgcgggctga attggatagt tttaggtgga gacattccac ttgggttaat gctatcatag 1260 ctttcatgct caaattctgc aaataaagaa agagcatgcg aagagtttct atcgttaagt 1320 gaaggcatgt ccattttcat tgatatggga gaaggcgata caaaaggaga agaatcaata 1380 tccattactt cttgagattg caaattctta ggctcacgtg gagtcacttg tacttgccaa 1440 tttgtatcta aaacgcgatg cagaagggca ctacgacctg tatgaggatt attttctggt 1500 tttcttagcg gagtctgcat ccttgccggg atgggggtca aagctgcatc atctaacgaa 1560 atatcctcta aggagacatc catcttctta ggagtggact gtacaaaatc ctcgtttttt 1620 gtattatctc cttgtacagc tgcatcggga aaatcagatt ttccgacaaa agaatgcctc 1680 ttttccaaat gttcattctt tgtgtgcagc tgtaggtccg cctctgtaga attagacata 1740 acatcttgat cgcttggatt ggattctact ggaacaggtt cctctacacc cgaaagtgaa 1800 acattggcac ttgcttcaaa aaactgcttc caaaactgtt ttctgttagc ttaattctta 1860 aaataataca aattacaagc tgaatcatga gtggcagttg ccattgaaca tacttttgaa 1920 gagtcccata tagtgttaca attttttgcg tatttttcca cgataggcaa gattttggta 1980 gtcactgttc gatgacattt agaaaaattt gcatcaattt cgtaaagtgc tagagtaatc 2040 gattgttcca atcgttctaa tctaattctt ttgttagaga atgtttatct acagtcgcga 2100 caagtttact gcatactgtt ccaaattgtt cataagaatg acatctaata ctcataaaaa 2160 ctttgaaaat attatttctt agtatagaaa ctctcaatgg tgaaatttat ggcgaactgc 2220 aactgaggtg taggtatact agcgtccatt attagcgatg tttcgtaaag taaacaagtt 2280 aaattggcaa tatacagtga gatttttgta agttcaagat aatactaata caatcattgt 2340 tgagtaataa atatgaattt taaagttttg tttactttcc tcagtggact aaatgcagac 2400 tgcaatgatc aaatgatcca tagtaaacaa acattcaact tgtcttttgc cagcatcctc 2460 aagatccaaa atgagtagta tctttggaga gaatattgtt tcagatagta tagtaaatat 2520 ggagttgacg aaccctgata atactacgac tatgcatccc atctatgaaa ctaacattga 2580 aaaggaagtc cagcaggagt tttctgacaa tgtctctgaa aaagaaacga ttgactcaac 2640 taaaagcaaa atatctttag aaaatataca gcaagaaatg ggagcacttg ccaagaaaat 2700 ttttcataaa ttaggggtta aagcaaccga cttgggattt tctaatgagc atgatgactc 2760 gcaggattca ttacagacac tagcgccttc tccatcatat gttccacttt tgaaggttat 2820 tggaagctct gaggaggtca atagcaactt ggtattaacc gacttggaaa caaatactga 2880 tggatatgat cctaaatttt tgatttctgt taggaagttt ttgatgggat ctcccaactc 2940 tggctttgtc gttaaacatg agaaacgtct tccagatgga ccgcgtgttc tggcccttcg 3000 agccatttca tcagtcgatg aagaaaatag aaaagagcgc ctatctcctg atagtgatcc 3060 tgttgaaaca gaatctgttt atgttgacaa tggagaattg tcaaatcaaa aagtagaaac 3120 agttgaaatt tccgaaaaag aacaaaatga tgatcccgcc ggatattctc aataccttct 3180 agagttcaag aagagtaaat gtcaaaagaa agtgccgact ttagagagta ttgaggaaaa 3240 tgaaggaacg gaacctcatg acaacttgac ctttatgact gatttgggaa ctccatacta 3300 ttctctgggt aatgaatttg aaagaaagca aattttggat gaatacgggt tgctggctaa 3360 tgatgaaaac ctagttattg gacacacgtt aagagcggag tattgcttta tgtttgatga 3420 aagcgatatc ctgcaattac gcaattatga acatacagaa aaggaactta gtgtccttca 3480 atttaaaggg gtctcgtcac gttgggattt tcgttgctgt agagaagaac gtttactccg 3540 attgctacta tgtttcgaca gtgaacatac tgggcaatct ttcattcaac tgaacgatcc 3600 tgaaaatgaa aatgaaaagg aagaacaaaa ttccattagc attagggaat tatcctactt 3660 cagcacaaaa cttatttcat tgatcttacc caaagaagca cataagcagc ggtatatcat 3720 gctaagctcc ttagcaaaga caagggaagc tgatttcttt tggtctgaag aggaaaaaac 3780 taattataca aacgagcttc tcagcaaccc atgcaaattc ctttgtgaac tagatcattt 3840 cgattcattt cctcatcaac aacaagatct actctggaag tacttagcgg agttttctgc 3900 tagtttagag ttagacccca accttgccct ttggaagaag caagttattt tttcaaaaat 3960 cggtcatccg aagttgctgg ttatgccaat atctagtttc cactgcgtac aacgtttccc 4020 tgaccttgtt tgcgttcaaa cttcaactgc tgaaacgttt ttgtctgtgg atcgtgaatt 4080 aacaacttat gacctaaaca ctattaagtt gttaaacaca gcacctagtc gtacagctca 4140 aaactggctt tttatcatgc atcacctaga aattgtaggc tatttatttc cacatttggt 4200 tcatctcgat aaacagtata gtttattaga ttatgcaaag tctgttgagc acattccaga 4260 attgggcact gtacaacgaa aagggttttt gaacaaagtc gcatttgatg ataacgaggc 4320 tttactttac caagtttaaa cgtactgtca cataattttc tatcacatgt tatcgaccat 4380 tcagtgttga ggttcctagg aatctcttct aggatggtag tgtacctttt aagcgaaatt 4440 ttgtttcatc tgcacattca ttatttacaa acctatacga acttgacaaa agtttttacg 4500 aatatactaa atattgactt attaatactt gaaaatatta tcactttttt tgaggtggtc 4560 taagtaaaaa tgtgtaggtc gaattcgtca catagggtaa taaatgtaag tgtaggaccg 4620 ttaaagtatg ctctaaataa tcttttaaca tataaaaagt aatgtggatt atttgcaaac 4680 accataatga atgttgatca aaataccggt tcaacgtcga taaataacaa acagcagagc 4740 ccaccgatac acaaacctaa aattgcaaag ggactttaat agtcgtataa tctggagaat 4800 gaaatgctta gcgaccgatc attgcaacgt gataataggt tggcttaggt gctttgttta 4860 tttacatttc aatgttagtt gtcatggaaa cgaaattcat acaaaataaa gcgtatgcgg 4920 ctgtaaacaa acaaaagatt caacatttac atttacccat tttacccaaa aatggggttt 4980 catggatgtt taagtacaga tgaatatgaa cctgagttaa ttgagaaata tgggaatcct 5040 gaaccacctt cttcaagcat attaattaat acacgaccag tcaatccatt tttatccact 5100 ttcgtgtatg taggaaaggc tagcagttct gaagatgtgt ctatatctac aggtgaggag 5160 gaaatgcgaa cccttttagt tgcgtctgct gttaaagatg caaaaggttg ggtgtacctt 5220 tccggaaaag acgttgaaga aataaaacag aaaataaaaa acctgcaggg attacttggt 5280 gtttctataa aaaaactggc tgtcgaagcc aaaattagag aagctgctaa gaatttgatg 5340 gttgcccaag ctaaggagaa aaaaggaaaa cataaacaaa gtacgataga gcattacgaa 5400 caatgttctc gtagagttag agaactttct tctaagatat ggcttattga aaggaaactt 5460 gcagaatttt atatgcacct attgaagcat atggttgctg tgtgcattgc tgagcttaaa 5520 ccaggtagct gtagcaaggt atcttcaccg gtttctgcca tcaccgctga tgagagcgca 5580 actggatttc gagatgaaga aataatgaac aatgaggaaa ttgagcagct tgtagagcgt 5640 atgagccgta tactggaaat tgctcaatca atgggtaatt caattcgtga accatctgtc 5700 ctagatgcag tacaaatgaa cgctggtgaa cggctactcg agcaagttcg tcacttagag 5760 cttattttga aacaaatata cgagaaaaag ttggaggaag atgctgatgc gaaagatatt 5820 gctcctcgcg ctattgtgaa cttttggcgg ttacttactg agctgtttcg cggcgacaat 5880 gatacgccag agaagagtaa tgcacttcct gatgatgaac tcgataaaca tttgaaatct 5940 gattttgaca ttgaatcatt ttgctttctt ctgcaccatc tattgtcatt ataccaaaca 6000 caaaagaaag agcttgcttc aagcaatgaa cttctagcaa gtgtccgaga tgaaaatacg 6060 aaaaagctta aggagcttca agatatcatt gaagagcaga gtaaacatat ggctcgcctt 6120 catagggaag ggttttctga ggccgctgaa aataacgata aacctaaaga aacaatgcct 6180 tgtacgtatg attcatctct agcagatgac cattcggata cctccaacct gagtaaagat 6240 aaggcgaata cactttgtgc ccagtgttca gtatatcttt ctgaaaagta tcagcaacag 6300 cagtccttgt tgcaattgga gtctaatatc cagcaattgg aaaatgagaa aaaagctgcc 6360 aagcttatag aaaaggatct gttgtctcag atttctcatg tcaaactgca atttgagcaa 6420 caaataaagg cacatcatta tgcgaaagac caggttagaa atttgaacga cgagatggtt 6480 gccttacgtg ctgagcttga agttgtaaag gctatgaatt cccagcctga tgatcccgat 6540 tccgattatg caataaagca gaacaatgca ttgcagaaca gattagaggc tttgacaaga 6600 gaaaatgagt tattacaatc tcgcgttaca actttggaaa tggaaaaaga agttcaggag 6660 aagaactctg ctactgtaag caaccttacg ctaaagcaat tgcaaatgga gaatatattt 6720 gcaagcctca atttggagaa ttcatttgat tttggtatgc cattaatggg accatacact 6780 caacaaaatt tgcagttaga ggatgaaatt tctgaaattt ctagtccttc ctattcctcc 6840 gatgatgaca ggaaaaccat ctccgagact caaccagcac ctaagcaaaa cattaacgaa 6900 gaatttgaaa attcgacttc tacagatggg tctgaaacta acaaaaatga acaagggaat 6960 agtcttagca cccctgataa tgaaccgcgt ttgaggaagg agagcttgag cagtgatgtc 7020 ctacttgacg gtagcgagaa accagcgcaa gctgaattaa ctataaattc agaaaacttt 7080 ccagttgact gtagccttcc tgttcaaacg ggtgctgacg tcgttgtccc tgatacaact 7140 gatgaagaag tcataacctc agaacccgtg aagttagaac aaccgatcaa tgaaaacagc 7200 aatgtagaag aagctgaaaa ggattatcag ccgtctgaga aagatgacaa atctcttatt 7260 ggcggcatcc tcagtacagt tgaaatgacc cagtctactg atgtgaatga cgagattgaa 7320 aatactttaa ccatacctgt tgaggtagag cattctgata atattgacaa aggcagtgaa 7380 gaaaatgatc ttggaaaaga agccgttgat gaagcaaaca acaaccagaa tgatgttcta 7440 gaatctgtcg tggtggaaca atctactaca actgatgact gtgaaaacaa agtatatgaa 7500 ggacaaatga acgacaaaaa ttcctccctt gatatggtca atgcatgcga aggtattaat 7560 cagactgcaa ttgggttcgt tgagaagcct gacaaggtta ctgagctaat cgatgaagct 7620 gaagaaaaca tcgatatatc tcaggacatc tctatgaccg agacgaacgc tgtagatgat 7680 gaagtgcaag cagaaaactc catcttacaa gatgaagttg aagaaactcg tcaagatgat 7740 atcgagaagg atgagctgga agacatcaag gaagtaaaag aggatgaaaa tttaactact 7800 ttagaggaaa caattgagat tccggccaac gatattgaag tccaggaccc tgaacaatgt 7860 tcatgtatga acagtactga aaatgataat atcactactg agaattcaag cgaaatcgta 7920 caagttattc atacagaaga cgattccttg cattttgatg acaatgtttc aaccgattca 7980 gtaagtctgg ggaataagtc taggataagc atggattcaa tgagaaacga ctgtgaagcg 8040 tttttgccga aaaaggaaaa attcggctct ttaaggactt tacacagttt tgaaagtagt 8100 atgaggagag tatctacttc tgcagcataa ccaaatacga tcttctaaat ttgcagctgt 8160 ataaggaaga tgttccgatt ataaactttt ttccttcttg gacctttttg caggtgcttt 8220 caagtttttt tttgaatttt ggctaagaag caaacgaaag attttgaaga ctatgctttc 8280 gcaactttat gaacgcagta aattctgctt atgaatggtg catacaacgg tttatggact 8340 tgcatattta ttttattctg gcattaattg cattttgctt taccagttgg agattgaatc 8400 gaagttttat ataagatacc aactaataat gcgtgtacaa aaagagacaa cagacgcatt 8460 tacattacaa ttagcatcta aagaagtgat aacatcaagc atatataata catttaataa 8520 tactaatgag catatgtatc ttcaacccat atgtaaccga atcttcctta tgacaagcat 8580 tattgatatt gcaagtttta aggcacaagt attgtttcta aatatcttta tgatcaaata 8640 ataattagct tatttgtaat agcttgtctt cgatcatttt ttgtaactat tgctacaaat 8700 attattcatc gaaacaaact aatttaccaa tttaccacct agcaaattac ccaaatcttt 8760 aaatcgtaaa aattttaagg aaaattaaat cgccatcaaa atattaacaa tatggtataa 8820 agactttttt aaacatgaac tatcagaaaa atgcaaaagt cctttgatgt agcggccaaa 8880 gctttttagt ttaaatgcat gatagtacaa tcatcagtac atctttaact cagaattcag 8940 gagaaacaaa tattgtacct catatactaa caaaatgata gtatgatact tttattataa 9000 tcggattaaa cgaaattagc actcagcaac ttcatttgat ttacgtggag aacttttggc 9060 ctgttgcata gccaaggcaa aaatacgact ggaatttgca ttttcattta ataatctttg 9120 attccaatgt gagcctgact gctgtattag tggtatatct tcgttgcgaa ttacagagcc 9180 gatggacatg aaaaagccaa aagtggccgc agatgttaac atgtattgac ctaaggtcct 9240 taagaatcca cgtggaccag gcccatagcg caaaactgct actcctccaa ataaaaaccc 9300 gatgccaagt ccagcagctg aacccataat ggcgcccatt tttactgttc agtgttaatg 9360 actgaattca tacaatatag aacttacgct tatccacagt tgaaggttgc atagattgca 9420 ttttgagtag ttaaaggtct tacttttatt tagaaataga gagcactagt ttcaaggggg 9480 attttgttgg taggaaaagt aaggtagtat acagttatta tattggatac ctaggtataa 9540 caatagatgt aacaatttct tttgttaaat caatagttta gtttaggaaa tgttaattta 9600 aagaaaacct atatatatat tttttataag cccagttttt ttaagtaaat gtaacaatgt 9660 attacatcca ggcatgcgtt aagtgagagc ataggcttaa cgttataatg acttctgaat 9720 taaaataaaa cattgcattg gcatgtattg caattgctaa agtctgctat gtatatctga 9780 catatataat aaattaattc ccctcggctt cggattgaat ttcctacctt ttgttattaa 9840 gaagcctatc gctaattaat tactaacatg tccttagcga aatttaattg agttgcattc 9900 ttagttacat ctacaaatgg caaagttcta atgagggagt gttgtcattc ctgcagcaat 9960 tattttatta tttaatagac aagtagaaca taaaagaaca aaaatggata tatgtatata 10020 tatatatata tatatatgtc aaaaaacatt attttaaaga tagccttcgt cagacaattg 10080 tgaaaggaca gcaaaagtaa cctcagaaac agagtctttg ggcttgatgt ttacggtagt 10140 ccactcagca ggtactttaa cagatgcatc agcatcagcc agagaaacaa caacggcagc 10200 accagcacgt tgcaattctt gggcgtaaaa cactgaaata gcatctaagc gaggtaaaag 10260 agtgacatgg cggcgaccat cctcgttcaa ggctgaaact agagcgctgg ggagaagttt 10320 atcggaggtg gcaggaacag ccaaaacaaa tccttgagag tatttgggag gataggattg 10380 acgtaaaata gcgacaacct ctggataaga gaaccactca gggatgttgg caccgacgcg 10440 aagacggcga cgaagttcag taccactgat gttcaaagta cgggtaccgg gttcgacttt 10500 gtcaactggc ttgtagatgt cctcatcagg aaggtaagtc atcatttgga aaggaacaat 10560 ggtgataccg atttcctgag cgtattgttc aacaaggtac tgagcatcgt aaggaccata 10620 aaaatcctcg ccttgactgt tcttaccagg accagcatga tcacgaccaa tgatgaaatg 10680 agaagcaccg tagttcttac gaatgatggc gtgccataaa gcttcacgag gaccagccat 10740 acgcatggct aagggaagaa gagagagctt ggcggaaccc ttaggatagc gttggagaat 10800 agcctcgtaa acacgcacac gggtgaagtg atcgatatca ccaggcttgg tcataccgac 10860 gacagggtga atgagcacac gggcaccgtg ttgcttagca gcacggacgg taagctcacg 10920 atgggcgcga tgcatgggat tac 10943 //