ID SPBC24C6 standard; DNA; FUN; 26129 BP. XX AC AL031786; XX SV AL031786.1 XX DT 30-SEP-1998 (Rel. 57, Created) DT 01-FEB-2000 (Rel. 62, Last updated, Version 2) XX DE S.pombe chromosome II cosmid c24C6. XX KW 5s rRNA gene; Aldehyde dehydrogenase; ATP-dependent RNA helicase; cdc14; KW cell division control protein 14; coatomer epsilon subunit; KW DEAD and DEAH box helicases; delta-1-pyroline-5-carboxylate dehydrogenase; KW dna repair protein; G-protein alpha subunit; G10 protein homolog; KW mismatch repair protein; mutS family; proline-trna synthetase; KW Tf1 type LTR; ubiquitin-like protein. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-26129 RA Skelton J., Lyne M, Churcher C.M., Barrell B.G., Rajandream M.A.; RT ; RL Submitted (29-SEP-1998) to the EMBL/GenBank/DDBJ databases. RL Schizosaccharomyces pombe chromosome I sequencing project, Sanger Centre, RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: RL barrell@sanger.ac.uk XX DR GOA; O74764; O74764. DR GOA; O74765; O74765. DR GOA; O74766; O74766. DR GOA; O74767; O74767. DR GOA; O74770; O74770. DR GOA; O74772; O74772. DR GOA; O74773; O74773. DR GOA; P27584; P27584. DR GOA; P36589; P36589. DR SPTREMBL; O74764; O74764. DR SPTREMBL; O74765; O74765. DR SPTREMBL; O74766; O74766. DR SPTREMBL; O74769; O74769. DR SPTREMBL; O74771; O74771. DR SWISS-PROT; O14399; UBL1_SCHPO. DR SWISS-PROT; O74767; COPE_SCHPO. DR SWISS-PROT; O74770; PHK_SCHPO. DR SWISS-PROT; O74772; CWFE_SCHPO. DR SWISS-PROT; O74773; MSH2_SCHPO. DR SWISS-PROT; P27584; GBA1_SCHPO. DR SWISS-PROT; P36589; CC14_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC5H10.01c. CC SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c24C6 is overlapped at its 5' by SPBC12D12, EM:AL035085 CC and at its 3' end by cosmid SPBC19G7, EM:AL021839. XX FH Key Location/Qualifiers FH FT source 1..26129 FT /chromosome="II" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c24C6" FT /map="IIL" FT misc_feature 1..666 FT /note="nominal overlap with cosmid SPBC12D12, EM:AL035085 FT S. pombe chromosome 2" FT CDS join(complement(606..623),complement(540..557), FT complement(356..468),complement(218..305)) FT /db_xref="SWISS-PROT:O14399" FT /label=ubl1 FT /note="SPBC24C6.01c, len:78" FT /gene="SPBC24C6.01c" FT /gene="ubl1" FT /gene="SPBC12D12.08c" FT /product="stress-induced ubiquitin-like protein" FT /protein_id="CAA21145.1" FT /translation="MLIKVKTLTGKEIELDIDPNDKVSRIKERVEEKEGIPPSQQRLIY FT AGKQMADDKNAESYHLEGGSVLHLVLALRGGSC" FT misc_feature join(complement(356..468),complement(227..305)) FT /note="Match to PF00240 ubiquitin, Ubiquitin family Score FT 99.22" FT misc_feature complement(306..323) FT /note="ctaacaaacatcacgtag, splice branch and acceptor" FT intron complement(306..355) FT /note="confirmed intron" FT misc_feature complement(350..355) FT /note="gtaagc, splice donor sequence" FT misc_feature complement(469..484) FT /note="ctaaccaaaatataag, splice branch and acceptor" FT intron complement(469..539) FT /note="confirmed intron" FT misc_feature complement(534..539) FT /note="gttcgt, splice donor sequence" FT misc_feature complement(558..574) FT /note="ctaatatataatcatag, splice branch and acceptor" FT intron complement(558..605) FT /note="confirmed intron" FT misc_feature complement(600..605) FT /note="gtaaga, splice donor sequence" FT CDS join(750..784,914..2699) FT /db_xref="GOA:O74764" FT /db_xref="SPTREMBL:O74764" FT /label=SPBC24C6.02 FT /note="SPBC24C6.02, len:606, SIMILARITY:Saccharomyces FT cerevisiae, SPB4_YEAST, atp-dependent rrna helicase spb4., FT (606 aa), fasta scores: opt: 1257, E():0, (38.1% identity FT in 580 aa)" FT /gene="SPBC24C6.02" FT /product="putative atp dependent rna helicase" FT /protein_id="CAA21146.1" FT /translation="MSFQSINIDKWLKNAVAAQGFKKMTPVQANAIPLFLKNKDLVVEA FT VTGSGKTLAYLLPCFDKVTRRDTDETGLGALIVAPTRELATQIFNVTKELLAYQPDSLD FT GGKKLVADMYIGGKGTLTNDLASFREKNPSVVIGTPGRLNEMLSHISSKHLEILILDEA FT DTLIDMGFQRTLQSIISQLPKQRRTGLFSATMNDTVSSFLKIAGLRNSVRVSVTVTSKK FT IDTRTPSSLAIQSLVIPPIYKVQCMIHLLCTIEYEKAIVFFSSCASVEYFNSLFLTYKL FT PFEIVALHGQQVQSNRSRNFEKFKKSNKKTVLFTTDIASRGLDIPNVDFVLQLDPPLDP FT KSFSHRCGRAGRAGRAGVAIVLLNDGREEEYEELLRVRKVPITRIDTPIEALDLSRLKV FT LTHELRKIVSKDRDLYDKGLRAFVSHVRAYTKHHASFIFRIKDLDLGQLATAYALLHLP FT KMPELKDTEISENIFKKFDIDYATIPYRDQVREQARRRRLEVEKTEPKKLARPAKIKNE FT AWSKQKEVKEKRNTRREKRKSKKEFLKAQKNEASNNLKQEIVSKAGAQETENDDLIDEE FT SDALSELEEDYRQLKKSKKRKNQASFGFSM" FT misc_feature 785..790 FT /note="gtaagt, splice donor sequence" FT intron 785..913 FT /note="confirmed intron" FT misc_feature 900..913 FT /note="ctaacataaactag, splice branch and acceptor" FT misc_feature 948..1634 FT /note="Pfam match to entry DEAD PF00270, DEAD and DEAH box FT helicases" FT misc_feature 1011..1034 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 1689..1940 FT /note="Pfam match to entry helicase_C PF00271, Helicases co FT nserved C-terminal domain" FT rRNA 3072..3218 FT /note="5s rRNA gene" FT CDS 3391..4668 FT /db_xref="GOA:O74765" FT /db_xref="SPTREMBL:O74765" FT /label=SPBC24C6.03 FT /note="SPBC24C6.03, len:425, SIMILARITY:Homo sapiens, FT CAB55948, hypothetical 45.7 kd protein, (409 aa), fasta FT scores: opt: 1084, E():0, (41.8% identity in 404 aa)" FT /gene="SPBC24C6.03" FT /product="putative proline-trna synthetase" FT /protein_id="CAA21147.1" FT /translation="MLQHLRNRASIEVLGKAIRKYNVPESANQLLIDMGFIQPSMPGIF FT QYLPLGLRVQNKICDLLHISMRSLGASAISLAHLSSKEIWEKSGRWQKTGSELFRLHDR FT NDREMCLAPTHEEDVTRTMATIIDSQKQLPIRVYQIGRKFRDELRPRGGLLRGREFMMK FT DLYTFDIDKASAMKTYEDVLQAYHTFFKEVGLPFVMVKAATGNIGGNLSHEFHYRHPVG FT EDVIYTCPSCHYSTNSEMLDLSKTSSDISCPNCNDQLTSTTAIEVGHAFYLGKIYSSKF FT NATVEVKNKQEVLHMGCYGIGVSRLIAAVAHVTKDAKGLVWPSSIAPWKVLVVPTSDNH FT IQSAETVYDATANVVGFDNVLLEDRQNRAFGYKMRDAELIGYPFVIVVGSRFQEEGICE FT IIVRSSGERYKLDKDSLHQVLLGNFL" FT misc_feature 3439..4608 FT /note="Pfam match to entry PF00587 tRNA-synt_2b, tRNA FT synthetases class II (G, H, P and S), score -20.80, E-value FT 0.014" FT misc_feature 3820..3882 FT /note="PS00179 Aminoacyl-transfer RNA synthetases class-II FT signature 1" FT CDS 5623..7269 FT /db_xref="GOA:O74766" FT /db_xref="SPTREMBL:O74766" FT /label=SPBC24C6.04 FT /note="SPBC24C6.04, len:548, SIMILARITY:Agaricus bisporus, FT PUT2_AGABI, delta-1-pyrroline-5-carboxylate dehydrogenase FT precursor, (546 aa), fasta scores: opt: 2044, E():0, (54.5% FT identity in 547 aa)" FT /gene="SPBC24C6.04" FT /product="delta-1-pyrroline-5-carboxylate dehydrogenase FT precursor" FT /protein_id="CAA21148.1" FT /translation="MSQFAEFKLPAIKNEPPKHYGPNSADREGIVKAYKELEAELPVTI FT PVIIDGKEVETNTIGEQRCPFEHKKVVARYHRAGAKHVEDAIEAALRGKKVWESLPFAD FT RSAIFLKAAHLISTKYRYKLMAATMIGQGKNIWQAEIDAGMEIIDFLRFNTKYASELYA FT SQPPENTPGVWNRMEYRPLEGFVYAITPFNFTAIAGNLAAAPLLMGNVVLMKPSDHAVL FT SSYIVYQIFREAGLPAGALQFIPGDAVEVSKVCFNHPEFAGLHFTGSTAVFRSLWGTIG FT ENVANGKYRTYPKIVGETGGKNFHLVHSSAEIKSAVVNAVRAAFEYQGQKCSALSRLYV FT SKYAWENGFRDELTKQVKSLKVGAPLTDFANFVGPVIHQASFNKLKKVLESAASDSEIE FT VLAGGKADDSEGFFVEPTVLLSKNPKHDIFVNELFGPVLSVYVYEDDNLDAVCDLIDTT FT TPYGLTGSIFAQDRVVVRKLTDRLRNAAGNFYINDKCTGAVVGEQPFGGARASGTNDKA FT GSGMILSRFVSPRSIKDTFAYADSVLYPSNF" FT misc_feature 5770..7230 FT /note="Pfam match to entry aldedh PF00171, Aldehyde dehydro FT genases" FT misc_feature 6511..6534 FT /note="PS00687 Aldehyde dehydrogenases glutamic acid active FT site" FT misc_feature 6595..6630 FT /note="PS00070 Aldehyde dehydrogenases cysteine active site FT " FT CDS join(7873..7903,7948..8783) FT /db_xref="GOA:O74767" FT /db_xref="SWISS-PROT:O74767" FT /label=SPBC24C6.05 FT /note="SPBC24C6.05, len:288, SIMILARITY:Bos taurus, COPE_BO FT VIN, coatomer epsilon subunit, (307 aa), fasta scores: opt: FT 230, E():2.7e-08, (25.0% identity in 296 aa)" FT /gene="SPBC24C6.05" FT /product="putative coatomer epsilon subunit" FT /protein_id="CAA21149.1" FT /translation="MFSWEASLSNELYFVRQYFYSGNYTKLFEIDTTSMSEKGLELTEI FT YMARAKLALGESLESIQSILTQKTPGSAAILALAGEGNMELIIDQHGNSDSVVQTLGAI FT FQIKNGSFDDAMDLLKKSVENLEAVALQVYIHLREHKIEAAEQTLKQALDWADEEIVLQ FT LAQSWIKIVSGGVESYNDAFYVFEELNGTDSNPMTLTGMACADICLLRPEEALSSLKTA FT LDSQPNYEEALSNMTTAITDLGPDAPSQAKNILSSFTNSSTLKLNDHLNEKAQEFDTFS FT TQFLSTA" FT misc_feature 7904..7909 FT /note="gtaaga, splice donor sequence" FT misc_feature 7934..7947 FT /note="ctaatatttgatag, splice branch and acceptor" FT CDS 10705..11928 FT /db_xref="GOA:P27584" FT /db_xref="SWISS-PROT:P27584" FT /label=gpa1 FT /note="SPBC24C6.06, len:407" FT /gene="gpa1" FT /gene="SPBC24C6.06" FT /product="guanine nucleotide-binding protein alpha-1 FT subunit" FT /protein_id="CAA21150.1" FT /translation="MGCMSSKYADTSGGEVIQKKLSDTQTSNSSTTGSQNARVPVLENW FT LNIVLRGKPQNVESSGVRVKGNSTSGGNDIKVLLLGAGDSGKTTIMKQMRLLYSPGFSQ FT VVRKQYRVMIFENIISSLCLLLEAMDNSNVSLLPENEKYRAVILRKHTSQPNEPFSPEI FT YEAVHALTLDTKLRTVQSCGTNLSLLDNFYYYQDHIDRIFDPQYIPSDQDILHCRIKTT FT GISEETFLLNRHHYRFFDVGGQRSERRKWIHCFENVTALLFLVSLAGYDQCLVEDNSGN FT QMQEALLLWDSICNSSWFSESAMILFLNKLDLFKRKVHISPIQKHFPDYQEVGSTPTFV FT QTQCPLADNAVRSGMYYFYLKFESLNRIASRSCYCHFTTATDTSLLQRVMVSVQDTIMS FT NNLQSLMF" FT misc_feature 10930..11925 FT /note="Pfam match to entry G-alpha PF00503, G-protein alpha FT subunit" FT misc_feature 10942..11028 FT /note="PS00107 Protein kinases ATP-binding region signature FT " FT misc_feature 10945..10968 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT CDS 12637..13359 FT /db_xref="GOA:P36589" FT /db_xref="SWISS-PROT:P36589" FT /label=cdc14 FT /note="SPBC24C6.07, len:240" FT /gene="cdc14" FT /gene="SPBC24C6.07" FT /product="cell division control protein 14" FT /protein_id="CAA21151.1" FT /translation="MEDLLNNAKQHLCMRNPKLIRIGLRQVESIVYHVAKPSHDDKIPR FT EIFLKLQDSPLYNSTTPCIYALDSLLEYQQNEEAYEKNFQFIQKLIDDLLHVIEGLVLI FT HPKSQTLFEDKATLRLFIHLLQPSQPSMLQVAAMKTLVCIMADRPLAIRLFEQINGLQQ FT ICVVFKHKQTSQDTRFQILEFFYFYLSPEPYSIDVIAYRKTRTEKQAYLSKYLSNVQGL FT RDDLDKFQPFGKLDETFD" FT CDS complement(13541..14644) FT /db_xref="SPTREMBL:O74769" FT /label=SPBC24C6.08c FT /note="SPBC24C6.08c, len:367" FT /gene="SPBC24C6.08c" FT /product="hypothetical protein" FT /protein_id="CAA21152.1" FT /translation="MDVVFALGHFCEAEGPSIIFCTQKLHRSTVSKFFEHPTSKRSIGV FT TENGNDSPEAFKNELDNRNNADSQSLQSSTESLFKADSEDYLCKKVSKGPESPRVNSFH FT NSYSRNQSPISRKSSCVTCSTVLPLEFSVPDVQPRLYTNSSTNPDVLYMSSQHPHTQQR FT YSTLKRLMVRCLSCEYSTLSEASDSMSNPLFFGDQDNGYVISQSFSLRDPSARGGLRRY FT AIIATCPNQLDLILRYSFISEKFLHIVQFLRISSFNTKNDYSSSRSKTTASSSNGTFAS FT PSFNISSLSGSSNIGTAPSYEISSSIGANVSSLAHTQRLPSFSFLRRRDDIGEGRSLVD FT ITCWDGIFVGLHSSFSWILEVWDLLVV" FT CDS complement(15629..18106) FT /db_xref="GOA:O74770" FT /db_xref="SWISS-PROT:O74770" FT /label=SPBC24C6.09c FT /note="SPBC24C6.09c, len:825, SIMILARITY:Synechocystis sp., FT P74690, hypothetical 92.4 kd protein., (821 aa), fasta FT scores: opt: 1195, E():0, (39.0% identity in 777 aa)" FT /gene="SPBC24C6.09c" FT /product="hypothetical protein" FT /protein_id="CAA21153.1" FT /translation="MATQNDIPNSTPEDLAKQVEIAEKHPDPPAMPSRLPDSLKTLEAK FT IDTSKITDEEVANVHRFQRACDYLAASLIFLSNGLYTGGDLEEKDIKTRLLGHWGTCPG FT LSIVYSHCNRIINKYDLNMLFVVGPGHGAPAILSALFLEDSLGPFYPRYQFTKEGLNNL FT INTFSLPGGFPSHVNAEVPGAIHEGGELGYALSVSYGAVLDRPDLIVTCVVGDGEAETG FT PTATSWHAHKFLDPAESGAVIPVLELNGYKISERTIYGCMDDSELLSLFSGFGYEVAIV FT NDTPDQNRVMAATMDWAVERIHDIQHRARVNREEIKPRWPMIILRTPKGKGCPKYLNGK FT FLEGTFRAHQVPLKLARTDTNQRNLLKDWLNSYNCQDFLDEHGLPTKGITEHLPPREKR FT MGQRHETYNSYLPLKVPDWKKYGVKKGETTSATSVVGQYLDELLVTNDSTLRIFSPDEL FT ESNKLDGALKHSYRTMQTDPELMAKRGRVTEVLSEHLCQGFMQGYTLTGRTAIFPSYEA FT FMTIVVSMLVQYSKFLKMGLETGWHGKFGSLNYVTSSTWARQEHNGFSHQSPRFITTML FT SLKPGVSRVYFPPDANCFLATVARCMKSENTINLMVSSKNPQPAYLSVEEAEHHCKAGA FT SVWKFASTDNGENPDVVIAGVGNEIMFEVVKAAEMLQNDIPELRVRVINVTDLMVLSSL FT HPHGMNPAEFDSLFTKDRHVHFNYHGYVMDLKALLFDRIQGTRVTMEGYREEGTTTTPF FT NMMMCNNTSRYHVARMALQHALHNPTVAVNCNMLCAKYAWKLEEIENYIMENKDDPPEI FT YAAPVFKNKTSTL" FT misc_feature complement(18107..22177) FT /note="low complexity gene-free region" FT LTR complement(20312..20664) FT /note="Tf1 type LTR" FT CDS join(complement(23463..23517),complement(23278..23367), FT complement(22178..23157)) FT /db_xref="SPTREMBL:O74771" FT /label=SPBC24C6.10c FT /note="SPBC24C6.10c, len:313, SIMILARITY:Saccharomyces FT cerevisiae, Q12342, orf ydl146w., (491 aa), fasta scores: FT opt: 294, E():1.7e-13, (25.9% identity in 417 aa)" FT /gene="SPBC24C6.10c" FT /product="hypothetical protein" FT /protein_id="CAA21154.2" FT /translation="MEFTDVFYNLENEKQFLAEIDELLTIPYEKNELEIGVSKFLSFIN FT KYGEPYLITEFQLQRCMEKFLNSPLYQLDENAVLSIFYDCFFFLKEQQTLKFIIIVFQS FT EIQENEYCLRLLASTGFIPVLIKAMKQFKDRSENVAFTSFRYALFLVYYICRSRRLSPT FT DLVAIDEYFLVNLFKTSEEAWNDEDMDSFGMCVLTLLSINEQFMLVRLASKGSFEIANG FT IMDLLSSSKVDNGIYSEGLVFTLNREKDPRSRMLILKQLFLLFTTPATYEIFYTNDLNV FT LIDIFIREINNIPDELSDLRYAYLQVLIPLLENTQVRHPPHYKTKCIVDAVNNVLISHS FT KSSNMEDARTTDVAIRVLEVPWLQQEMKSLGTAQ" FT misc_feature complement(23158..23178) FT /note="ctaacaaaataaattcaatag, splice branch and acceptor" FT misc_feature complement(23272..23277) FT /note="gtaatg, splice donor sequence" FT misc_feature complement(23368..23384) FT /note="ctaacatttggtgacag, splice branch and acceptor" FT misc_feature complement(23457..23462) FT /note="gtatgc, splice donor sequence" FT misc_feature join(24071..24102,24173..24552,24597..24616) FT /note="Match to PF01125 G10, G10 protein Score 269.92" FT CDS join(24071..24102,24173..24552,24597..24625) FT /db_xref="GOA:O74772" FT /db_xref="SWISS-PROT:O74772" FT /label=SPBC24C6.11 FT /note="SPBC24C6.11, len:146, SIMILARITY:Drosophila FT melanogaster, O97454, l(1)10bb., (144 aa), fasta scores: FT opt: 641, E():0, (60.4% identity in 144 aa)" FT /gene="SPBC24C6.11" FT /product="g10 protein homolog" FT /protein_id="CAA21155.1" FT /translation="MPRLRTSRTKRPPDGFDEIEPTLIEFQDRMRQIENTMGKGTKTEM FT LAPIFQLHHQRSRYIYDLYYKREAISTELYNWLLKQNYADGNLIAKWKKPGYEKLCCLR FT CIQTAESKFGSTCICRVPKSKLDKDQRVRCTHCGCNGCASCD" FT misc_feature 24103..24108 FT /note="gtatgt, splice donor sequence" FT misc_feature 24159..24172 FT /note="ctaattagctatag, splice branch and acceptor" FT misc_feature 24553..24558 FT /note="gtaagt, splice donor sequence" FT misc_feature 24584..24596 FT /note="ctaatgaaaatag, splice branch and acceptor" FT CDS complement(24824..26129) FT /codon_start=2 FT /db_xref="GOA:O74773" FT /db_xref="SWISS-PROT:O74773" FT /label=msh2 FT /note="SPBC24C6.12c, len:>434aa" FT /partial FT /gene="SPBC24C6.12c" FT /gene="msh2" FT /gene="SPBC19G7.01c" FT /product="dna mismatch repair protein Msh2p" FT /protein_id="CAA21156.1" FT /translation="LRGRSSHYTELSTQKNGVYFTTKRLHSLNNSYMDHQKSYRYHQNG FT LAREVIKIAATYGPPLEAIGQVIAHLDVILSFAHASTVAVIPYVRPNIVDSSIAQEKHG FT QSSNILDIVSLEDTPNFEEIRRTLENNHCARLYLKQARHPCLEAQDDVKFIPNDVNLEH FT GSSELLIITGPNMGGKSTYIRQVGVITVMAQIGCPVPCEVADLDIIDAILARVGASDSQ FT LKGISTFMAEMLETATILRAATPRSLIIIDELGRGTSTTDGFGLAWAITEHIVTQIGCF FT CLFATHYHEMTKLSEEITTVKNLHVTAYVGDSESKDVALLYNVCEGASDRSFGIHVAKL FT AHFPPKIIEMASNKAAELEAEDSGAQGDTQEVKSKKEGMAIVRDIMRQWRSNVKPEMTQ FT QQMMDQFQKVIGSFAQQINSNNWLQSRVSTNEVSS" FT misc_feature complement(25076..25726) FT /note="Match to PF00488 MutS_C, DNA mismatch repair FT proteins, mutS family Score 436.23" FT misc_feature complement(25841..25927) FT /note="Match to PF00488 MutS_C, DNA mismatch repair FT proteins, mutS family Score 31.38" FT misc_feature complement(26026..26129) FT /note="nominal overlap with cosmid SPBC19G7, EM:AL021839 FT S.pombe chromosome 2" XX SQ Sequence 26129 BP; 8335 A; 4679 C; 4858 G; 8257 T; 0 other; gatcaccaaa acgtcttaag tttagaaaag cttaagcaat atttttatac aaatcaatag 60 attcacataa aatgaaacag agcaataata aagcgactca attctcattt cgttactctt 120 agtattagta aaacagtaaa aagatttcgt ttatagcgtt aaataaaagt atgatttttt 180 atacataatt tttctttata aataaagtat gcaacaacta gcaacttcct ccacgaagag 240 ctaacacaag atgcaagacg ctgcctcctt ctaaatgata actttcagca tttttatcat 300 cagccctacg tgatgtttgt tagaatcatt gtatggatgt tcccatagtg cttacatttg 360 ctttccagcg tagatcagac gctgctgtga aggagggata ccctcttttt cttcaacccg 420 ttctttgatc ctagaaacct tgtcatttgg atcaatgtct aattcgatct tatattttgg 480 ttagaaacat agatgaatta taactgcata taaatgtttt caacatttaa aacacgaacc 540 tctttccctg tcaatgtcta tgattatata ttagtataca taaaaaagaa ataaatttat 600 cttactttta ctttgataag catgctaact tttataaacg cttttctgaa attgttgtgg 660 ttaaacgcta gcagttcctc tctctcccta taagcattcc cctctggctc acctcgcgaa 720 aaattgaatt ggtcttcaaa gaggggacaa tgagttttca gagtattaat atagataaat 780 ggctgtaagt tttcaattct aaaataaaaa ttttaggttc tgctacatgt ttaacctgtt 840 caaaaatttt tattatctaa atgataccag gattttgtca aatcaacaat ttacaagcac 900 taacataaac tagaaagaac gccgtagctg ctcaaggatt taaaaaaatg acacccgttc 960 aggctaatgc cataccatta tttttgaaaa ataaagatct ggtagttgaa gcagtaacgg 1020 gttcaggcaa gactttggcc tatttacttc cttgcttcga taaagtcact cgtagagata 1080 cggacgaaac aggtttgggt gcattaattg ttgcacctac tcgtgaatta gctacacaga 1140 tattcaatgt taccaaagag cttttggcgt accaaccaga ctctttggat ggagggaaaa 1200 aactcgttgc agatatgtat attgggggaa agggaacgct cacgaatgat ttagcttcat 1260 ttcgggaaaa aaacccctca gtggtgattg gtacacccgg tcgattgaat gaaatgcttt 1320 ctcatatatc cagtaagcat ttggaaatac taatattaga cgaagctgat acccttattg 1380 acatgggatt tcagcgtaca ttacaatcca ttatatctca acttccgaaa caacgtcgaa 1440 ctgggttgtt tagcgcaaca atgaatgaca ctgtgtcatc atttttaaaa attgctggcc 1500 ttcgaaatag cgtacgtgtt tctgtgacag ttacatcaaa aaaaattgat acaagaacac 1560 cgtcaagtct agctatacaa tctttagtga ttcctcccat atacaaagta caatgtatga 1620 tacatttgct ttgtacgatc gaatacgaaa aagcaattgt ttttttttct tcttgtgctt 1680 ctgttgaata ttttaactcc ctttttctca cttataaatt accgtttgaa atagtagctt 1740 tgcatggaca gcaagttcag tcgaatcgat cacgtaattt tgaaaaattt aagaaatcaa 1800 ataaaaaaac agttcttttt acaactgaca ttgcttcccg gggtcttgat attccaaatg 1860 ttgactttgt tcttcagctc gacccgcctt tggatccgaa atctttttct catagatgcg 1920 gcagagctgg tcgcgctggt cgagcgggtg ttgcaatagt tttgttaaat gatggaagag 1980 aagaagaata tgaggaattg ttaagggtta ggaaggtacc tattactcgt atagacactc 2040 caattgaagc tttagatctt tcacgactta aagtattaac ccacgaattg agaaaaatcg 2100 tatccaaaga cagagatcta tatgataagg gattaagagc gtttgtttca catgttcgtg 2160 cgtacacaaa acatcatgcg tcgtttattt ttcgtatcaa agatttggat ttgggacagt 2220 tggccacggc atacgcttta ttacatcttc caaaaatgcc agagttaaaa gacaccgaaa 2280 tatccgaaaa tatttttaaa aaatttgaca ttgattatgc aaccatacca taccgtgatc 2340 aagtacgcga gcaggccaga cgacgccgat tggaagtcga aaaaactgaa cccaaaaaat 2400 tagctcggcc agcaaaaatt aagaacgaag cttggtccaa acaaaaggaa gtaaaggaga 2460 agcgtaacac ccgacgtgaa aaaaggaaat ccaagaaaga atttttgaag gcacagaaaa 2520 acgaagcttc taataacctg aaacaagaaa tagtatcaaa agctggagca caagaaacgg 2580 aaaacgatga cttaatagat gaggaatcgg atgctttatc tgaattagaa gaggattacc 2640 gacagttgaa aaaaagcaaa aaaagaaaaa atcaagcatc ctttggattt agtatgtagc 2700 aatgtatttt tagggaatgg aaaaaaaaac ggggttttgg aaatatagga aagtctttta 2760 gtatttttaa atatttgaga acttggaaga ttaattggag ttgttcagca aatattaagt 2820 tcttattcat cagcatttat ttttgaatta ctgcatttgt atatttactt tacatttaca 2880 acgattactt aacaaatttg tgaaaaatgc aattaagcgt ttatctacac ataattctgc 2940 gatcaatttg atatttaaga agtaaaatac tttaagcaac tgaagcagta gatacattca 3000 ataaatttag attacatttc cacaattaat tccaaatttt ttttactaaa atctggttaa 3060 ggatatcata tatatatttt actaattact tatagtgctg tctacggcca tacctaggcg 3120 aaaacaccag ttcccgtctg atcactgcag ttaagcgtct gagggcctcg ttagtactat 3180 ggttggagac aacatgggaa tccggggtgc tgtaggctat tcctaacttt ttgctagcct 3240 tattgcaata aggaggtcaa ctcagttatt tatttggacg aacccagcgc ctatttcgat 3300 tactattgac aaactacttc tattggatca tttattttgc gattctgaaa ttttttatat 3360 gcttttgtat aaaaacacca tgtttaaaaa atgctacaac atttaaggaa tcgtgcatcg 3420 attgaagtgc tagggaaagc gatacgtaaa tacaatgtcc cggaatcagc gaatcagtta 3480 cttatagata tggggtttat ccagccgtct atgcctggaa tttttcaata tttacctctg 3540 gggttgcgtg tacaaaataa aatatgtgac ttgttgcaca tatcaatgcg ttctttgggt 3600 gcttcagcga tcagtttggc acatctttct agtaaggaga tatgggagaa aagtggaaga 3660 tggcaaaaga ctggaagtga actttttcgt cttcatgacc gaaatgacag agaaatgtgc 3720 cttgctccta cccatgagga agatgttact cgcactatgg ctacaatcat agattctcaa 3780 aagcaattac cgatacgtgt ttaccagata ggtcgaaagt ttcgggatga attacgtccg 3840 cgaggtggtc ttcttcgcgg tagagagttc atgatgaagg atctttatac ttttgatatc 3900 gacaaagcat ccgctatgaa aacttacgag gatgttttgc aagcatatca tacttttttc 3960 aaagaagtgg gattgccatt cgtgatggtg aaagctgcta cgggtaatat tggaggaaac 4020 ttatcacacg aatttcatta tcgacaccct gtgggagaag atgtaatcta tacatgtccg 4080 tcttgtcatt attcaacaaa ttccgaaatg cttgatttgt ctaaaacatc cagtgatatt 4140 tcatgcccta attgcaatga tcagctaact tcaactaccg cgattgaagt aggacatgcc 4200 ttctatcttg gaaaaattta ttcctccaaa tttaatgcaa cggtagaagt aaaaaacaaa 4260 caggaagtcc ttcatatggg atgttatgga atcggtgttt caagacttat agctgcagtc 4320 gctcatgtaa ccaaagatgc aaagggttta gtgtggccat cgtcgatagc tccttggaaa 4380 gtactagttg ttcctacttc tgataatcat attcagagcg ctgaaacggt ttacgatgcc 4440 acggctaacg ttgtaggctt tgataatgtg ctgttggagg acagacaaaa tagagctttt 4500 ggatataaaa tgagagatgc tgagttgatt ggatatccat ttgtaatagt tgtaggatca 4560 agatttcaag aggaaggaat atgtgaaatt attgttcgtt cttcaggtga acgatataaa 4620 cttgacaaag attcactgca tcaagtactc ttgggaaact ttctttaaat ttgtcaaatc 4680 ctacaatatt tttttatgct atgagagtaa tctaatgtca agaatttaac ttatcgttca 4740 aatagatacc atttctactt gtgaacattg gaaaaaagct tttttgtcca aaaattatat 4800 caatgcaaaa tgctgaaatc atcatttcga taaaatttgt tttgtagtat cagacaaaaa 4860 ctcgttccgc tttattgata tcttactatt ttataaacat taaaaaagtg tcatgtttcc 4920 ttcctacttc tttttgtaat tcggttttct gcaactatag tttgaactca taaattaaat 4980 cagatacaca atctgaggat cggatgcaaa actaagtttg aagtaatccc tgcaaagagc 5040 tagctgattc aatagtacga agcaagagtt taatattaac aatcataaag atttgcgcta 5100 gattacaatt taagcgaaat acaattccaa gccttcaggc tatctattta atagttcggt 5160 aagataatgt gaagatgtcc gagtgtgatt aaaagcagtt aaaacacttc cctttgaaat 5220 aaatcaaata atacgaccaa agaccaacaa gttcagggtt cacttctata agtctcataa 5280 tcaatatttt agctgatttt ttaagcaaaa ttgcaaattc cacggagtgc gatcacatcg 5340 acactacctg tttataagaa tatataggag tatatatata agaggcaaat ctctgtcagg 5400 atatttccag aacaccaata cctcaataca ggcgattaga aaggaaacga tttctaacgc 5460 tctttaaacg tttggattga aactagtaag tatttatatc tatgtaataa ctgttttgag 5520 tgagacccct acgcgtcttt tcattgcttt ctatctttag gttttctacg ttttatttat 5580 gcgatattaa tacttattag atttatttca tttttaagta aaatgtcaca atttgctgag 5640 ttcaaattac ctgccattaa gaacgagcct cctaaacact atggtcccaa tagtgctgac 5700 agagagggaa tcgtcaaggc ctacaaggag ttagaggctg aattacctgt cactatccct 5760 gtcatcattg atggtaagga agttgaaacg aataccattg gtgagcagcg ttgtcctttt 5820 gagcacaaaa aggtcgttgc tcgctatcac cgtgctggtg ccaagcacgt tgaagatgcc 5880 attgaggcag cacttcgtgg aaagaaggtc tgggaatcct taccttttgc tgaccgttct 5940 gccattttct tgaaggctgc tcatttgata agcaccaagt accgttacaa gctcatggct 6000 gctacaatga ttggccaggg taagaacatc tggcaagctg aaattgacgc tggaatggag 6060 atcattgact tccttcgctt caataccaag tatgctagtg aattatatgc cagccaacct 6120 cccgaaaaca ctcctggtgt ctggaaccgt atggaatatc gtcctttgga aggtttcgtt 6180 tatgccatta ctcctttcaa ctttacagct attgctggta acttggctgc tgcccccctt 6240 ctcatgggca acgtcgtttt aatgaagcct tctgaccatg cagtcctttc tagctacatt 6300 gtttaccaaa tcttccgtga agctggtctt cccgctggag cacttcaatt tatccctggt 6360 gacgctgttg aagtctccaa ggtttgtttc aaccaccctg agtttgctgg tcttcatttt 6420 actggtagca cagccgtctt tcgtagcctt tggggaacaa ttggcgagaa tgttgccaac 6480 ggaaaatacc gcacttaccc caaaatcgtc ggtgagactg gtggtaagaa ctttcatctt 6540 gtacattctt ccgctgaaat taagagtgcc gttgttaatg ctgttcgtgc tgctttcgaa 6600 tatcaaggcc aaaagtgctc tgccctttct cgtctttacg tttctaagta tgcttgggaa 6660 aatggtttcc gtgatgagct taccaaacag gtcaagtctc ttaaggtcgg tgctccttta 6720 actgattttg ctaattttgt gggccctgtt atccatcaag caagctttaa caaactgaag 6780 aaggttcttg agagtgctgc ttccgattct gaaattgaag ttttggctgg cggtaaagct 6840 gatgattccg aaggtttctt tgttgaacct accgttttac tttctaaaaa ccctaaacat 6900 gatatattcg ttaacgaatt gttcggcccc gtactgtctg tttatgtata tgaggatgac 6960 aacttagacg ctgtttgcga tctcatcgat actaccactc cttatggttt aaccggatcc 7020 atcttcgctc aggaccgtgt tgttgtcaga aagttgactg accgtctccg taatgccgct 7080 ggtaacttct atatcaatga taagtgtact ggtgctgttg ttggtgaaca accttttggt 7140 ggtgctcgtg ccagtggtac taacgataaa gctggtagcg gaatgattct gtctcgattc 7200 gtttctcctc gctccatcaa agatacgttt gcttatgcag actctgtttt atacccttcc 7260 aacttttaag tttgttttgg cctttttgat ttggatttaa tttttagaat ttagatagac 7320 attggagttg tagagtgttt tactctgtac tttgatactg ccataaaaaa gaccacaacc 7380 tttttttttt tgggtttagt acaatatgtg aggaataaag gaagtatata tatatatata 7440 tattgattag ttaccttgag ttaaactcaa actttcaaag gtagtctagg ttttacaatt 7500 tttttttttc ttttttttta aagctcgcca tttgttattc taataaatta taatgttcgc 7560 tttgttaaca tgtattgatt tataacacta gatttgttgc attgtatata aaagccagtg 7620 gaccaaaatg tagtttgctg gtgattcttg aatacaacaa cgacctgtag aaaaaggatc 7680 tcaattatcg aacattttac ttgctgactg cgaaatatat tatattaggc ttcggagcaa 7740 ttagaaaaat tacaagtctt gatggaaagt tcgtttgctt tacattttgt tgtagggtta 7800 ctcatgtaca aacaccatta acccacatac tctctactcc acacatcgcc caacataatt 7860 aaaactttta acatgttttc atgggaggct agtttatcta atggtaagag atgagttggg 7920 aattaaataa caactaatat ttgatagaac tgtattttgt tcgtcaatac ttttatagtg 7980 gaaactatac aaagttattt gaaattgaca cgacatccat gtctgaaaaa ggtcttgaat 8040 tgaccgaaat ttatatggca agggcaaaat tagctttagg tgaaagttta gaatcaatcc 8100 aaagtatttt aactcaaaaa acgcctggat cagctgctat tctggcgctg gctggggagg 8160 ggaacatgga gttaattatt gaccagcatg gcaattcaga cagtgtggta caaacattag 8220 gagctatttt tcaaattaaa aatggttctt ttgatgatgc aatggattta ttaaagaagt 8280 cagtagagaa cttggaggcg gtggcgcttc aagtatacat tcatttacga gagcacaaaa 8340 ttgaagctgc tgaacagaca ttgaaacagg ctttggattg ggctgatgaa gaaattgtac 8400 tacagctggc acaatcttgg attaaaatag ttagtggagg cgtcgaatcc tataatgatg 8460 cattttatgt ttttgaagag ttaaacggaa ctgatagcaa tccaatgact ttaactggta 8520 tggcgtgtgc agacatatgc ttgttgagac ctgaagaggc tttgagctcg ctgaaaactg 8580 ccctcgattc tcaaccaaat tacgaggagg cactatcaaa tatgactact gcaatcacgg 8640 atttaggccc tgatgctcct tctcaagcca agaatatact ttcatctttt acaaattctt 8700 ctacactgaa gttgaacgat catttaaatg aaaaggcgca agaatttgat actttttcaa 8760 ctcaattttt gagtacggct taatccaata ataatattgt ttagaatctt caatccatta 8820 ataaacttca aatgtttgca tttttagtat ttattcattg actattgctt cactcaagta 8880 atggctcgtt gatctgtctg gcaaagcaag tcaatccagt attgcctcga taaatttcaa 8940 gtttaccaga agtaaaggta ttaaactaat taattagaaa tacttaaccg catgcagaag 9000 aagactcatg tagacataat aacaagaaaa cgcacccgaa tatatctcga aatgaaacat 9060 ttaaatgaac gccgtcacaa caggagcgtc tttaaaccgt ttacttttat ttatcaaata 9120 cattcattaa ttaaaaatga actattatga ctatccacct atatatttgt ttttaaaaat 9180 ctagaatagg tggttcttgt ccaaaattac tcaaaacctg cagtgccaca aaatgacaag 9240 caacaagttt gcctttacaa atagaaaaga aagatgtttt gaaatacaca ggtgtttgga 9300 atttggaaaa agcaagaaaa ccgatattaa acgataagac tttaagaatc gaagatgaac 9360 ttgctcaaac ggcagtggca ccatgacaga ttacaactat atatgccaac atttgcttaa 9420 ccccaacatg tatcaaaact ctttaactag caaacgttca tttttgcgac atcgaacact 9480 taaataagca tgtatgaacg tatcagtttg taactctctt tgtaaattta gcgttacttc 9540 gctcaaaata gttggattgt tgtgtagtat taacacatac tacatacacg catttgttgt 9600 attaagattt gaatcggtac gcagagtaaa agagatactt gctactgttc attctgaatc 9660 ctattaataa atgatgttga agttcatact gtcaaatatt tgtacatttt catcctcccc 9720 attcttccaa attcgcacta tagcattgaa agcgggcaca tattgtgagg atgttgctct 9780 tagagaaaaa tgcagatgta aatacaccga agtactatca acttaacttt ttagataagg 9840 tctttgttgt agaaacttct tttattcgga ctgttgacat ttgccaggtc cgttggatca 9900 ctagacatac aaaaaaatat tctgttaaaa tcgacaagac actataagca cgtaccagtg 9960 aaagtataac gatttcactt ttccaataag taaaaagcct ttgtttctgt aattgtttca 10020 ttcttacgaa ttctaatagc tcgcttacca cctgatagtg tacacgcatt gtagttacct 10080 ttttcaacat ctcaacttct ttgacggctt agcaatctta gtatccattt aggaagtatt 10140 aaaggagaac aggtatttgt aactcccttt atagttggag accattgctg ctcattaaaa 10200 ccctggtttc tttgtaaatt gtacgcaatt ttgttttttg ggttgctttg tttacattaa 10260 aggagttgat ccactgattt ctcattcaaa aattaaacag ttcttgattt aatttcatct 10320 aataccttat cgcaaccgtg atagtataat aaatttgact gtttacgaat accaaagttt 10380 gtttgtgtca ttacacgatt tttctcaaag aatcctcctg gtttttttaa ccaaattgtt 10440 taaataatag tttcttttta ctatataata gtattctttt ggatctcttg gaattatctg 10500 gcaattgggt tttttgctta tagttgggtc cacttcacaa atatttgaga tttaacgaca 10560 tctattattt cttttttaat ccaaaaatcc ttatttatca ccttttctgc tgtttttaca 10620 gaaaattgcg gagattaact ttctttgtct cgactttgaa ttatctcctt gtggggattt 10680 ggaatctgta gctgcctttt caccatggga tgcatgtcga gtaaatacgc tgatacatca 10740 ggaggagaag tcattcaaaa gaagctttca gatacgcaaa cctcaaacag ctctacaact 10800 ggaagtcaaa acgctcgagt tccagtcctt gaaaactggc ttaatatcgt cctgcgtgga 10860 aaaccacaaa atgtggaaag ttctggagta cgcgtaaaag gaaattctac ttcaggtgga 10920 aatgacatta aagttttgct cttaggcgcc ggtgatagtg ggaaaacgac cattatgaag 10980 cagatgagat tattgtatag ccccggtttt agtcaagtag ttagaaagca gtatcgagtg 11040 atgatttttg aaaatatcat ctcctctcta tgtcttcttc ttgaagctat ggataatagt 11100 aatgtctctt tacttccgga aaatgagaag tatcgggcag ttatcctaag aaaacacact 11160 tctcaaccca atgagccatt ttctccagaa atatatgaag ctgttcatgc cttgacattg 11220 gataccaaac ttcgtacggt gcaaagttgt ggtaccaacc tctctttgtt agacaatttt 11280 tattactatc aagatcacat tgatcgaatt tttgacccac aatatatacc ttctgatcaa 11340 gatatccttc actgtcgtat caagacgacc ggtatatcag aagaaacatt tctgttaaat 11400 cgtcatcatt accgattttt tgatgtagga ggacagagat cagagcgcag aaaatggatt 11460 cattgctttg aaaatgtcac tgcattgttg tttctcgttt ctttggcagg ttacgatcaa 11520 tgccttgtag aggacaattc aggaaatcag atgcaggagg cgttattatt atgggattcc 11580 atatgtaact ctagctggtt ttcagaatca gcaatgatac tttttctaaa taaacttgat 11640 ttatttaaaa gaaaggttca catttccccc atccagaagc attttcctga ttaccaagaa 11700 gttggttcaa caccaacatt cgtacaaact caatgccctc ttgccgacaa cgcagttcga 11760 agcggtatgt attactttta cttaaagttt gaaagtctta atcgcatcgc ttctcgtagt 11820 tgctattgcc attttaccac agctacagac actagtttgc tccaaagggt aatggtatcc 11880 gttcaagata cgattatgtc caacaatcta cagtcactta tgttttagat gaatttttcc 11940 ttaactatct tcataatctt ttctgtctca tttctctact ttcattcgca ctctaggaaa 12000 agcctctata cttttccgtg aatggtgtct ctagttaatt tccttgcatt ttgtatgcac 12060 ttcatgtgtt atttctccat cgaaactgtt aattagtgca ttctaattgt tttatttcat 12120 agcttcttcg aagcttcgtg taatcttata ttgttttaaa tagctcaaaa ttaactgcag 12180 tttttgttat ttgataattt tacgattaat acataactat tgtttaattt aatatctaaa 12240 ttttttcatg tcaaccgttt gagacaaact aaacccattg atattaatat aattaaatta 12300 ggcggatttg atcgtaaact aaatataaat ctataaggac tcgatgttgc ttgttttgtt 12360 attttaggcc cctttttcaa atatggctcc aattcgcctg ttaatattca attgtatcct 12420 atcttagcaa gctggtgttt tctctcccaa aacctcaagt tttagaaaat agcaatttaa 12480 tgtagctgct tcaacactcc accctactat ttatatcatt actaagaacg aatatagagt 12540 ctctttttta tctttaacta aacgaagatt caatttactt ttatttataa taaggatttt 12600 tattgcccgc ttggcatgag taaataatga tccggtatgg aagatctatt aaacaatgct 12660 aaacagcatt tgtgtatgag gaatccaaag ctaattcgaa ttggtttgcg tcaagtcgaa 12720 tctattgtat atcatgttgc gaaacctagt catgatgata aaattccaag agaaattttc 12780 ctaaaattac aggattcacc attgtataat tctactaccc cttgcattta cgctttggac 12840 agtctccttg aatatcagca gaatgaagag gcatacgaaa aaaactttca attcattcaa 12900 aagctaattg atgacttact gcatgtgatt gaaggattgg ttttaatcca tccaaaatca 12960 cagacgttat ttgaagataa agctacctta aggttattta ttcatttatt acagccatct 13020 cagccatcta tgttgcaagt ggctgcaatg aaaacgcttg tatgtatcat ggcagatcgt 13080 ccactggcta ttaggctttt tgagcagatt aatggcttgc agcagatatg cgtagttttt 13140 aagcacaaac aaacaagtca ggacacccga tttcaaattc tcgaattttt ctatttctat 13200 ttatcccctg aaccatattc tatagatgtc attgcctaca ggaaaacgcg gactgagaaa 13260 caagcttacc tatccaaata tctttctaac gtacaagggc ttcgagatga tttagataag 13320 tttcaaccat ttggcaagtt agacgaaaca ttcgactagt tagatgcaat gcctggtgca 13380 aaaaaatgtt taaagtctca ttgttaactt atttttgaaa atttagtatt catttactaa 13440 agaatttcta atgttaatgt taaattatta atcgatcatc ttactattga aagtattcca 13500 gcatcctata gcatttgtaa aaagtcaacc agttttactt tcatactact aagagatccc 13560 aaacctccag aatccagcta aacgaactgt gaagaccgac aaagattccg tcccaacatg 13620 tgatatcaac taaactgcgt ccctccccaa tatcgtctcg acgacgcaaa aaactgaaag 13680 aaggaagtct ttgtgtgtgg gccaaagatg acacatttgc accgatacta gaggatatct 13740 catacgaagg agcagttcct atatttgaag aacccgataa cgaagaaatg ttaaaactgg 13800 gggatgcaaa cgttccattg ctagaggagg ctgttgtttt tgaacgggag gaggagtagt 13860 cattctttgt attgaaagaa gaaatcctta gaaactggac tatatgaaga aacttttcag 13920 aaataaaact atatcgcaaa atcaaatcta actgatttgg acaagtagca ataatcgcat 13980 atcttcgaag tcctccccgg gcagagggat ctcttaaaga aaaagactga ctaataacgt 14040 aaccgttatc ttggtctcca aagaacaaag gatttgacat agaatcggaa gcttcagata 14100 gtgttgaata ttcacagctc aagcagcgaa ccattaatcg cttaagggta gaatatcgtt 14160 gctgagtatg tggatgttga ctagacatgt ataaaacatc ggggtttgta cttgagtttg 14220 tataaagtcg tggttgaaca tcaggtacag agaattcaag gggtaaaaca gtactacatg 14280 taacacaaga tgattttctc gaaatagggc tttgatttcg agagtatgag ttatgaaatg 14340 agtttactcg gggggattct ggtcctttcg ataccttttt acataaataa tcttcagaat 14400 cagctttgaa aagtgattcg gtagaacttt gtaaagattg agaatcggca ttgtttcgat 14460 tatcgagttc atttttgaag gcttctggtg aatcattacc attctccgtt acgccaatag 14520 agcgcttaga tgtaggatgc tcaaaaaatt ttgaaacggt agagcgatgc aatttttgag 14580 tgcaaaaaat aatggaaggc ccctcggcct cacagaaatg tccaagagca aaaacaacat 14640 ccattatgac tattatggaa atttggtgag ataaaagtgt ttagttgaca aaggcgatct 14700 gaaagcaaat gtttagaaag cgacaatgaa cttgaaaagt tttgatggtg tataatagct 14760 tctaaataat gccttcaaat ctaatgatta ataaggtgat acgttttaaa gtcgataaaa 14820 tgtaagatgt gcattcgttc gaaaacaacc ttttgtactt taccgattta ccaagcaaac 14880 attcagttat actgaggtat ttcgaaaaga ttgaggatta gaaaaaaaat ggattaaaga 14940 gcttgaaacg ctccagatac tgaaattgat atgaaaattc ctgataaatt agaggatata 15000 tgtgtgcgtc ttcatctcac acagtaccaa aatataataa acacactaga atctgtccag 15060 tttacattaa aagaattaaa aaaaaagttt ttctgtttgg aaaaagcggt tgattttctc 15120 acttcaagga atagaatgtt cagaagttta taccaagttc cacatttccg atattgtagg 15180 ggaatgctga agagtcgcaa atgagggaat ttacgaaaag ctagtaatta agaaacttca 15240 aaaatgaaaa cgaccttcat agaaaacaag taaaaatgcg agtgcgttga gagggggagg 15300 aagaggttaa aaactgacga gctacaaaaa agcgtaaggt atcaattagt gcctctactg 15360 tttcgattac taaatacagc cacaaactat tgatagtaat gtatataaga attggtatat 15420 taaatcgtgt aaaacacaat tgcaatatgc gcgcgaccgg gcaaatccaa gtcagctagc 15480 tacctaagtg ataccaccaa ccaatgtttg ggtacacccc aacactacaa gatatgctaa 15540 cgttttaatt aacacaaaaa cagatgtaat tttatttaaa ttctgtagaa ttatcattat 15600 ataaacaaaa agaatgcacc atttctatct ataatgtgga agtcttattt ttaaagacag 15660 gagcagcata aatttcagga ggatcatcct tgttttccat aatataattt tcaatctctt 15720 cgagcttcca agcatatttg gcacacaaca tgttacaatt aacggccacg gtaggattgt 15780 gtaaagcatg ttgcaaagcc attcttgcaa catgataacg agaggtattg ttacacatca 15840 tcatattaaa aggagtggta gtagtacctt cctctcgata gccctccata gtgacccgtg 15900 taccttgtat gcgatcaaac aagagagcct tcaagtccat cacataaccg tgatagttga 15960 aatgaacatg gcgatctttg gtaaacaaag aatcaaattc cgcaggattc ataccatggg 16020 gatgtaagct cgaaagtacc atcaagtcag tgacgttaat gacacgcact cggagctcag 16080 gaatgtcatt ttgaagcatc tctgcggctt taactacttc aaacataatc tcatttccga 16140 cgccggcaat aacaacatca ggattttcgc cattatctgt actagcaaac ttccaaacac 16200 tagcaccggc cttgcaatga tgttcggcct cttcaacaga taggtaggct ggttgtggat 16260 ttttactaga aaccataagg ttgatagtat tctcagactt catgcatcgg gcgacggttg 16320 ctaagaagca attggcatcc ggtgggaagt atacgcggct aacaccaggt ttcagagaga 16380 gcatagtggt gataaacctg ggtgattgat gggagaaacc gttatgctct tgtcttgccc 16440 aagtactgga agtaacatag ttcaagctac caaattttcc atgccatccg gtctccaagc 16500 ccatcttcaa aaatttggag tactgaacaa gcatactaac aacaatagtc ataaaggctt 16560 catatgaggg gaaaatcgcg gtacgtccag ttaaagtata accctgcatg aaaccttggc 16620 aaaggtgctc tgaaaggact tcggtaacgc gaccacgctt tgccatgagc tctggatcag 16680 tttgcatggt acgatatgag tgcttcaaag cgccatctaa tttattactt tccaactcat 16740 cgggtgagaa aattctaagg gttgaatcgt tggttacgag gagttcatca agatattgac 16800 caacgaccga agtggcacta gtggtttctc ccttcttgac accgtatttt ttccaatcag 16860 gtaccttcaa aggtagataa gaattgtatg tctcatgacg ctgacccatg cgcttctcac 16920 gaggcggaag atgctcggtg atgcccttag taggaagtcc atgttcgtct aagaagtctt 16980 ggcagttgta gctgttcagc caatccttta gaagattgcg ctggttggta tcggtgcgag 17040 ccaatttcaa aggaacttgg tgagcacgga aggtaccttc taaaaatttg ccattcaaat 17100 acttgggaca tcctttaccc ttaggggtac gaaggataat catgggccat ctgggtttga 17160 tttcttctct gttaacacga gcgcgatgtt ggatgtcatg aatgcgttca acggcccaat 17220 ccatagttgc agccataacc ctgttttggt cgggggtatc gtttacaatg gcaacttcat 17280 agccaaaacc gctaaacaaa gagagaagct cactatcatc catgcaaccg taaatggtac 17340 gctcggaaat cttgtaacca ttaagttcca aaacaggaat cacagcaccc gattcagcag 17400 gatccaagaa tttatgagca tgccaagaag tggcagtggg gccggtctct gcctcaccat 17460 caccgacaac gcaagttaca atcaggtcgg gacgatcaag aactgcaccg taactgacgg 17520 acaacgcata acccaattca ccgccctcgt gaatggcacc agggacctcg gcgttgacat 17580 gagaaggaaa accaccggga agggagaagg tgttaataag gttgttcaag ccttccttgg 17640 taaattggta tcgagggtaa aaggggccca aagaatcttc aaggaaaaga gccgataaaa 17700 tggcaggagc accatggcca gggcctacga caaagagcat gttgagatca tatttattaa 17760 tgatacgatt acagtgagag taaacgatgc tcaagccggg acaagtaccc caatggccta 17820 gcagtctagt tttgatatct ttttcctcga ggtcaccgcc ggtgtagaga ccgttggaaa 17880 ggaaaatcag ggaagctgcg aggtaatcac atgcacgttg aaaacgatgg acattggcaa 17940 cctcttcgtc ggtaatcttt gaagtgtcga ttttagcttc gagggttttt aaagagtcag 18000 gaagacgcga gggcatagca ggaggatcgg ggtgtttttc ggcaatttca acttgtttcg 18060 ctaaatcctc gggagtcgag ttagggatat cgttttgagt agccatattg aagaggaatg 18120 tttttataat ctaaaatcaa ttaaacggag tttgaaacag tttgtgaata aatggaaatt 18180 cgtcaagtcg taaatgataa atattcgtga aataagcaca catacacaca gagtatatag 18240 gaaggaggaa tgctagtaaa ctaggaaatc aagttttacc tagtacaaat gaggaaagtc 18300 gtaacaataa taaaccaaaa gtaaataaaa aataaataag gaataagaag atatggtgat 18360 gtaaaaagaa gaatagaagg gcaattatta atcaatgaat aggagtggaa tgaaattcaa 18420 aaaaataaaa gaaaaataga attctcacca aataaaataa tactttgtta attaattcta 18480 aattatcctt tattttattt tattttattt ttataataat tcaattccga tttaatttcc 18540 tttcctttcc ttttgttcgt aaccaaactt gagttgatga ttctatttat caaaaaaagc 18600 aagcgtcgta gcacatggat cgcgaggaca cacacgcata tatatattaa tttctgtatc 18660 attccattaa cagttgcaaa taacttatca tgatcataaa ctagtttcaa cacttcacaa 18720 acacatcatc atccttgttt tcattaaacc acgtatccga tcttacgtaa aagggtcgat 18780 tgcgtaaagt aggagtgaac gcaagatgta tcacgaagtg aacgagatta agtaaaaaaa 18840 agaaataaga aaaaaaaatt atgaaagaaa acatttatga gtcaaagaaa gagagaaaaa 18900 aaaaaaaaaa ctgttagtca tgaagcgaac attgaagaaa tggatagcga aaatggagaa 18960 taacaatgcc aaaaaggtga attcttataa atatgtaaac atttattgat ttgatttcat 19020 aaaaagttac ttttccttga aaccctccct tttctacact tacttacctg tgatgttcct 19080 tgtgagtcta ttgtccattg ctatttattt gactctttct ttaccttgta accattgatt 19140 tcttctcgcc atgctataga gcattataat gtactgtatt atactatatt acataacaat 19200 accgcactgc ataatacttg gcaggcaacg ttgatttgca ctaaatgcca ttgtaaccga 19260 aaactggaca ccctaaaaga gcactatgat ccattttagc aactgagctc atggtgacgc 19320 aaagtgctga aatcgactga attcgctcaa gaccgatcga tgtgctatga aggttggaaa 19380 aggtaagaaa ggacgttgga tttcgattat gtcagatgcc agcacgggcc cttttttgaa 19440 attttcaatt tcgcatcttc acgtggcagc gcagcgctgt gtagctggag gaagaaagga 19500 aggaaggaca agagaaaagg caatgcgaga gcagtagacg atgaagaaga agaacagacg 19560 ggtgaaacaa ttgtcatgaa gatgtaaaga aaagaaggag ctgagaatgt agagaaatgt 19620 gccaatgtca gatgatttgc gatttgtttg gctaaaagta tagaagaaaa cgaggttagg 19680 gttatggggt tacggttatt gaaggttaaa gaaatatgaa tgggaagaat tgttttggat 19740 gcatttcgta ttagattgta tgtatatgta aataaataga tatctttaaa tagataatta 19800 aaataatcat tacttttctt tgctttgttt taataaaagc tgatttgttt gaaaacacgt 19860 tcatgcagtc atcatatgga aaaaaattag taagagaaaa taagtaagaa caaattaaat 19920 aaaaaaaaaa taagaacaaa ataaaattaa aataaaataa attaaattca cattataaaa 19980 aaataacctt caaacttctc tctacaatga acgatgtttt ttctttttct cttcttctta 20040 ccttccttat cctttctcta cttccaacaa tgcaacaatt cgcttcctaa actgtaaaat 20100 ttttaggttc gtccccttcg gattactctt ttcaattttc agaaacttta cactccgtaa 20160 aggttcaaaa ctgtgtcatt gcatggtttg cgatgcattg gtttatctct catcatttca 20220 tctcttgaat ttacctactt gctcccatgt ttaccgaata gtcagcgtag gtgattgcta 20280 aggatagcga aatgaaaacg tcaatccact atatcagcta cgcagtttgg tatttgttta 20340 aggatacgta gagctgcggt gagttttcct tgtgatctat tatattacaa tacacaggtt 20400 gtataagtag caactggata taggtattgt attaactagg ttatgatgtt acctatcact 20460 gatatagctt ataactaaac tgaggaacga ggttcagttg gaactctatt tataatattt 20520 ctaaatagtt gttatcagcg agtatgtgta tagacagata gttacccgtg attatcaata 20580 aacggatctt agctagtatt ccaacatatg acatatagtg atacgcaacg tactatatta 20640 tagcgtagtg tagaattgct gacacactaa cggtttttgc aaatcatgtt gcttttcatt 20700 attacagtta gcaatcattt agatgtcaca tacggcaatg ctgtcatatg taaagcaagc 20760 agccactctt taggaaaaca atcgctggta ggagtgtgca agcagcaaac cattcttgta 20820 accgttaaat gatcgttttt attggtttca agtaaatctt tccattcaat ttttcctttt 20880 ttttttagtt cttcccccct ttacaaccag gattttcatt tttggttgga aactaatccg 20940 ttagattact cgattggtac attttaacta ttattcgtaa aactcatcac caaacggcct 21000 tgttgaaatt tattattcaa gctttgttac gaactcatgg ctggtaacgg cgcattacga 21060 agaagtgctc gagaaaaatg ctgggaagcc agagatgctt actttggttg tttggatagg 21120 cattccattt tggatggatt gaaagatgat acaaaagcag cccaggcttg ttccgctgaa 21180 aaaaccgctt tcgaaactga ttgcgtaaaa tcttgggtat gaatcgccaa aattgtaaat 21240 gaaatctggc tggtatgaaa tgaaacgaga aattccgatt ttgcaattct cttgaattat 21300 taccttaaag atctccatta cttctttttt tctttctcac taacattgtt tttctggatt 21360 aggtcaatta ctttctaaag tttcgagttc aacagcatca gcaacaagaa gctatcaaaa 21420 aactcgaggc tcaaggcgca aaaaagttga attagctgtt cctgaatact ctcatacaat 21480 ctcattgcat ctaggtttcc cccatcctaa tatgttttca tttttatgct taagtactta 21540 ttactcatct tcaactttgg caaatcaaac aaagcggtat tttttttttc ctgcccttcc 21600 tctgtttact ctgttctttc atttttgatg gtgaaatttt taactgaacc ctttcaaaag 21660 aaagttttgt gtttacgaat aatcacctat tttttcaaag acgacgatga atctaaatta 21720 cgttgtctaa cttgcacatt tacgatcacc gaaagttaca gaaaatgtta gatgattgat 21780 aggggtatta ttaattaagc attcctatat tagtttatgc cattcttcac gtttgttatt 21840 taaaaatttt cttcacttct tcttttgcaa tggatatgtc taactagaga ttttctattc 21900 attgatatga aaattgcagt gtttaaactt ttagcatttt ctttgcattc caaagaaatt 21960 tctccaagtt ttatcaattt tctgcaagaa gtaatacgcc aaaactggct tttcaaaaaa 22020 caacagactg gcaaaaggag agagaaagta ttaaaaaaaa gagtggaaag gagattggtt 22080 aaaatttgca attctttttg gttgatctga caataaatga aggaaacgag tgaggtgctt 22140 taaaaaaata aaaagttttt cagtagtaga ataaaaatta ttgagcggtt cctaatgact 22200 tcatctcttg ttgaagccac ggtacttcta aaacacgtat ggcaacatct gtagtacgtg 22260 catcttccat gttgctgctt tttgagtgag aaattaagac attattgacc gcgtcgacta 22320 tacacttagt tttgtaatga ggtggatggc gcacctgtgt attttcaagc aaaggaatca 22380 aaacttgcaa atatgcatac cgaagatccg aaagctcatc gggaatattg tttatttcgc 22440 gtatgaatat atcaattagg acattgagat cattggtata gaatatctca tacgtagcgg 22500 gagttgtaaa aagaaggaat agttgtttta gtattaacat tcgagagcgt ggatcctttt 22560 ctcgatttag agtgaaaact aggccttcac tgtagatacc gttatccact ttggaagagc 22620 tcagcaaatc cattatgcca tttgcgattt caaacgaacc tttggaagca agccgaacaa 22680 gcataaactg ttcattgatg ctaagcaatg tcaagacgca cattccaaaa ctgtccatgt 22740 cctcatcatt ccaagcttct tccgacgttt tgaataggtt tactaaaaaa tattcatcaa 22800 ttgcgactaa gtcggtcggt gaaagtcgtc tcgagcgaca aatatagtac actaagaata 22860 aagcataacg aaaagatgta aaagcaacat tttctgaacg atccttgaac tgtttcattg 22920 ccttgatcaa gacgggaatg aaccccgtag aagccaacaa acgcaagcag tactcattct 22980 cttgaatttc ggattgaaag acaatgatta tgaatttcaa agtttgttgt tctttcaaga 23040 aaaaaaagca atcatagaaa atacttaaaa cggcgttttc gtctagttga taaagcggac 23100 tattgaggaa cttttccata catctctgca attggaattc tgtaattagg tacggttcta 23160 ttgaatttat tttgttagat aagatgttct ataaagagac aaacactcaa tttctttgta 23220 tttcatccat aggaaaaaca cggaaaattg tgcttcccca attctccaaa acattacctc 23280 catatttgtt gataaaagaa agaaactttg aaacaccaat ttccagttca tttttttcgt 23340 atggtatagt taaaagttcg tcaatttctg tcaccaaatg ttagcgtcaa cgggaatact 23400 atttagccag gataatgaat cccaggcaca ttcaagttta caattatgaa taaattgcat 23460 acccgccaaa aattgctttt cattctctaa attataaaac acatccgtga actccatgtg 23520 gaggttaggg aaggtttaat tgccgctttc tcattatcga gcctagtatt caatagacaa 23580 aattctcgct aatatccatc gataatcaac tttaatatat gattagtagt caacacaaca 23640 gagcgtcaat gttataccat gaaaacagta ttgtagtatt atagtataca aatgcatctg 23700 gttccctttt ggccatatgt taaggtataa aatatagtgg agacacaaat tcaaaaattc 23760 tcaattatcc tcaattgaag aggctataat ttaattaacg gagaaaaaac ttagtttcta 23820 tagttaagaa tatcttgcaa cagtttcaat cgcggcagtc tattttacaa ggaatttaca 23880 ctggattctc acaaatccaa cttgcccata agtacactac caccaaataa gtaaaaggat 23940 aaaaactacc catcactaga tttcatttta tcggtttctt tatatttaat ctctttaaag 24000 caagcattcc ttattctgtg ttggtttatt gaagaaaagt cgtagtttgc ttaaaaaata 24060 ttctgttatc atgcctcgtc ttcgaacgtc aagaaccaag cggtatgtat accaagtatt 24120 ttccttgtta cctttatttt tacctacgaa gtaagattct aattagctat agccctcctg 24180 acggatttga tgaaatagaa cccaccctta ttgaattcca agatcgtatg cgtcaaattg 24240 agaatacaat gggaaaggga actaagacgg aaatgctagc accgattttt caacttcatc 24300 atcagcgcag tcgttatata tacgatttat actacaaacg ggaagccata tctaccgaac 24360 tttacaactg gctgctaaaa caaaattatg ccgatggaaa tttaatcgcc aaatggaaaa 24420 aaccaggata cgagaaactt tgttgtctgc gctgtattca aaccgctgag tcaaaatttg 24480 gttcaacgtg tatatgtcgt gtacctaaat caaaacttga taaagatcaa cgtgtgagat 24540 gtactcattg tggtaagtaa agaagtgcta ttgctaccag ttgctaatga aaataggttg 24600 taatggttgt gcaagctgtg attaattgga aaactagtgg ttcgtttccc atttatatct 24660 ttttatttgg ttattatggc aaatgaaaca gttttgggtt ataaaattca ttgatctatg 24720 gcttttcctc gttttagtaa aaaattattt tattcataaa atgcgcttcc aaaaaacatg 24780 taccttggtt gaattctttc aattagtacc ttgctcacat tcttcatgag gaaacctcat 24840 ttgtggatac cctggattgt agccagttgt tggaattgat ttgctgtgcg aatgagccga 24900 tgactttttg aaattggtcc atcatttgtt gctgagtcat ttctggtttg acgttgctac 24960 gccattgtct cattatatca cgtacaattg ccataccttc ttttttagat ttcacttctt 25020 gagtatcccc ttgggctcca gagtcttcag cttctaattc tgcggctttg ttgcttgcca 25080 tttcaataat cttgggaggg aagtgcgcaa gtttagcaac atggattcca aaactccgat 25140 cactagctcc ttcacaaaca ttatagagta aagctacatc cttcgattct gaatcaccta 25200 cataggctgt aacatgcaaa tttttgacag tagtgatttc ttctgatagt ttggtcattt 25260 catgataatg tgttgcgaaa aggcaaaagc aaccgatttg agtcacgatg tgttctgtaa 25320 tagcccacgc taatccaaaa ccatcggttg tgctagtccc tcgtcctaat tcatcaatga 25380 tgattaagga tcgcggtgtg gcagctctca aaatcgtagc ggtctccaac atttcggcca 25440 tgaaagtaga aatgccttta agctgtgagt cgctggctcc gacacgtgca aggatagcat 25500 caataatatc tagatcagcc acttcacaag gcactggaca accaatctgt gccatgacgg 25560 taataactcc aacttgacgg atatacgttg attttccacc catatttggt ccggttatga 25620 ttaatagctc tgaacttcca tgctcaagat taacatcatt gggtatgaac ttcacatcgt 25680 cctgagcttc caaacaagga tgtcgcgctt gttttaggta gagacgagca caatgattat 25740 tttctagagt tcttcgtatt tcttcaaaat taggagtatc ttctaatgaa acaatgtcca 25800 aaatattgct actttgtcca tgcttttctt gtgcaatgct tgaatccaca atatttggtc 25860 ttacataagg tattacagct accgtacttg catgtgcgaa acttagaatc acgtccaaat 25920 gagcaattac ttggccaatc gcctccaaag gaggaccgta tgttgcagct atctttataa 25980 cttcacgtgc aagcccattt tggtggtacc ggtagctttt ttggtgatcc atataagaat 26040 tgtttagtga atgaagacgt ttagtggtaa agtagactcc atttttttga gttgataatt 26100 ctgtataatg agaactacgg cctcttaaa 26129 //