ID SPBC216 standard; DNA; FUN; 25311 BP. XX AC AL049558; XX SV AL049558.1 XX DT 29-MAR-1999 (Rel. 59, Created) DT 29-MAR-1999 (Rel. 59, Last updated, Version 1) XX DE S.pombe chromosome II cosmid c216. XX KW coiled coil; hosphatidylinositol kinase; nuclear migration protien; KW phosphatidylinositol 3-kinase; protein transport; rad3 checkpoint protein. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-25311 RA Lyne M., Rajandream M.A., Barrell B.G., Oliver K., Harris D.; RT ; RL Submitted (26-MAR-1999) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk. XX DR GOA; Q02099; Q02099. DR GOA; Q9UUM2; Q9UUM2. DR GOA; Q9Y7K2; Q9Y7K2. DR SPTREMBL; Q9UUM2; Q9UUM2. DR SPTREMBL; Q9Y7J8; Q9Y7J8. DR SPTREMBL; Q9Y7J9; Q9Y7J9. DR SPTREMBL; Q9Y7K0; Q9Y7K0. DR SPTREMBL; Q9Y7K1; Q9Y7K1. DR SWISS-PROT; Q02099; RAD3_SCHPO. DR SWISS-PROT; Q9Y7K2; TOR2_SCHPO. XX CC Notes: XX CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. XX CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. XX CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). XX CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. XX CC The length in codons is given for each CDS. XX CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. XX CC Cosmid c216 is overlapped at the 5' end by cosmid c713 and at the 3' end CC by cosmid c646, EMBL ID SPBC646, EMBL accession number AL035216. XX FH Key Location/Qualifiers FH FT source 1..25311 FT /chromosome="II" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c216" FT /map="IIR" FT misc_feature complement(1..106) FT /note="nominal overlap with c713 S. pombe chromosome 2" FT CDS join(complement(539..1250),complement(1..480)) FT /db_xref="SPTREMBL:Q9Y7J8" FT /label=SPBC216.01c FT /note="SPBC216.01c, len:397, SIMILARITY:Saccharomyces FT cerevisiae, YNU1_YEAST, hypothetical 98.1 kd protein in FT spx19-gcr2 intergenic region, (858 aa), fasta scores: opt: FT 676, E():0, (35.3% identity in 382 aa)" FT /partial FT /gene="SPBC216.01c" FT /product="hypothetical protein" FT /protein_id="CAB40161.1" FT /translation="MDSTKEEEDLNNNIDEISDGENEEEELDEAIAAALQKIEVPSIPR FT RVKVYEMEDENWVDCGTGYCDGKIEGPLAYFIVRSEADNETILLKTQLIAEDIYSRQEE FT TLIVWQELNGTDLALSFQESSGCIDMWMFLANVQKAISSVTRSYSNDDILTDEGALNEN FT YLNTVDLPAPELANLKEIEEAVYGYMQSIQSRDSLVRYVSNENYIDRLIELFPLCEDLE FT NTDDLHRLCSIIKSFVQLNDAPLLESLFSNDEKLMCVAGILEYDPEFPNIKANHREYLM FT DSKKFKQVVPIQDPRILAKIHQTFKLQYLRDVVVSRIVDEPSFSVLNSFIFFNQADIIQ FT YLQTNEKFLHELFSIYVNEGEDDQRKQDGIFFIQQVCNIAKGLQFQSCSALFATFVK" FT misc_feature complement(481..494) FT /note="ctaatcgctgtcag, splice branch and acceptor" FT misc_feature complement(533..538) FT /note="gtatgt, splice donor sequence" FT CDS 2192..5098 FT /db_xref="SPTREMBL:Q9Y7J9" FT /label=SPBC216.02 FT /note="SPBC216.02, len:968, SIMILARITY:Saccharomyces FT cerevisiae, Q03767, num1p., (2748 aa), fasta scores: opt: FT 259, E():2.2e-07, (19.8% identity in 945 aa)" FT /gene="SPBC216.02" FT /product="hypothetical coiled coil protein; similar to FT C-term of nuclear migration protein" FT /protein_id="CAB40162.1" FT /translation="MEKKQDNEVELYSIDLKNRNESAKIKLAYAKALEESILCETRKIE FT QEIKDQVVQKENKTYFNNKFDNRYKLRDLEKNLAEEEVRITEMLTIQRQDIAIERRKNT FT NCFSESSQVDQYSVTETNLQYATNIGLNLLQQLRYLRLQLSEKEDLHKKLSVDNAHLIK FT QLDLLSSNMKTLMKEKTKVQGQRDLLEQRLQGLMKKLTEVESLTVSLNDEKNKLTLELT FT NLRICLHELQLNAEKGETIDESEDSKNTLVTEDENDDSVFLESSSDKYFDSSSFDAEQE FT EKHDFPIDPFLSLESNVQTSVSQSSAVLKSINLAKQELVSVNHLVADDTKTPSPNLSSE FT IIENTKADIKKSIRSLNKAVSPENSIDIEDETDRDDEFICFLLSYQQLQKALKSNLGLF FT QLSCLYPLSLNHLIQSFFQSLTSQISIKDIDSKNKQVIKLFKPTKSSDRQEIFELAQFE FT PRQKFPIDTNSSKCDMSASTEMHLKDTEKFANFKLKENILNHSSIYERDVSYLPALNKG FT GRENYLNNRVSSYRLVKPILNSYGNHVLNRIQHDILENHFCCLKNVKDFVCGANTISMQ FT WNLQKNMEFISSVFSLIKNEVNDTSANSVILRTDALSNVATTRLKRKLTSAIIDCSIPR FT RRLRHYSNPEIAEFKNFRLSTDISHSNVRNSKKLCSNGSMNCMRQGKAVFPRKIPYQEH FT DWEQWEKIAQSSMFKNRSIASRQSLETSDVTLDINMSSRHSNGTSSMLFKDFTKHNNWE FT ASTYPSAPKNTRTYPTAEVEKTRHDSSQSARQLKARSTATTISISLSTVSDVFTLPRNN FT LKSKTNTKKCRDNLNLSGLSSSTCNANSVNKLMKHVMMGNEMMKYPRSESFKMFKKSHW FT RYFWINPHCEMLCWSKTNPFIEKGRKNQVKSVKIKGMTIIKAPDALKNANLHNEVIVMQ FT TTDKPIVLKAKSKKIHNIWVQAIKQINHKAIFDTKPGI" FT CDS 6059..6802 FT /db_xref="SPTREMBL:Q9Y7K0" FT /label=SPBC216.03 FT /note="SPBC216.03, len:247, SIMILARITY:Bacillus subtilis., FT O07609, hypothetical 22.8 kd protein., (214 aa), fasta FT scores: opt: 234, E():5.1e-09, (31.2% identity in 234 aa)" FT /gene="SPBC216.03" FT /product="hypothetical protein" FT /protein_id="CAB40163.1" FT /translation="MTVFVVFGGHGKVALLFTKIATEAGHIVYNVVRDYVQNEDIEKVH FT GRTSVCSLEKATPNDIAQFLAEIHPDVVIFAAGAGGKGGPERTRAVDYEGAIKVYDAMR FT IAGIRRLIMISAIDNRDMSQPPPPYYTAADIELSEKIHQSIGTYYHYKYLADQELVRRS FT SDIDWTILRPSGMTDEKGSGKVALGKISINCMMSRENVARTVLLFALDNQSIHLVVDMT FT DGNVPIYKAIAGFVVKGESSYTYSV" FT CDS complement(7273..7689) FT /db_xref="SPTREMBL:Q9Y7K1" FT /label=SPBC216.04c FT /note="SPBC216.04c, len:138, SIMILARITY:Arabidopsis FT thaliana, G4115934, t4b21.5 protein., (139 aa), fasta FT scores: opt: 552, E():3.2e-31, (56.7% identity in 127 aa)" FT /gene="SPBC216.04c" FT /product="conserved hypothetical protein" FT /protein_id="CAB40164.1" FT /translation="MGFPLEKSEDEWKKELGPEKYRIMRQKGTEHPGAGRFTHQFPKQG FT VFVCAACKELLYKASTKFESHCGWPAFFDNLPGKVKRIEDNSYGMHRVEAVCANCGGHL FT GHIFKGEGYSNPTDERHCINSASLEFHNEATNDN" FT CDS 8482..15642 FT /db_xref="GOA:Q02099" FT /db_xref="SWISS-PROT:Q02099" FT /label=rad3 FT /note="SPBC216.05, len:2386" FT /gene="rad3" FT /gene="SPBC216.05" FT /product="rad3 checkpoint protein" FT /protein_id="CAB40165.1" FT /translation="MSQHAKRKAGSLDLSPRGLDDRQAFGQLLKEVLALDKEHELGRSN FT SLPSMTSELVEVLIEVGLLAFKHDDSKSEFISPKMLKEAHLSLQALMLILKRSPTVLRE FT IKSSVTLLDWILPRTISLFADIRFIKLFDSLKEFHKLIYQLISEKSFLWDLYASFMRYW FT KYYITNVSSIVLQITNATFPYKMPSPNSQPLQSITPNYPTHREDKFDLLIINIEEACTF FT FFESAHFFAQCSYLKKSNFPSPPLFTAWTWIKPCFFNFVILLKRISIGDSQLFLHLHSR FT IVQTLCCFSLNFIYHGLPICEKSKHILMSSINLTLGSLKKTYTVANTAISLFFLSLFVL FT PKTVAGLFYPFGVSLLSDFKVLEQLEPDSDLKKAIILFKCRYQSSEIDQTTLRAFGEIC FT TGKLENTLFSNSELNLFLLHYLSLDNDLSNILKVDFQNGHNICTFAKWCINNNLDEPSN FT LKHFREMLDYYSSHNVTISEDDLKNFSLVLCTHVAKVNEKTNSIFRTYEVHGCEVCNSF FT CLLFDERSLFKIPYHELFCALLKNPDIISSSVKQSLLLDGFFRWSQHCSNFNKESMLSL FT REFIMKALASTSRCLRVVAAKVLPIFIKGPNNLDIVEFHKESKALIFNTLKILAVENTA FT ILETVILSWISLSRVVEEEELHFVLLEVISSVINSGIFYQGIGLSALQQIASTRHISVW FT QLLSPYWPTVSVAIVQGMGKKPNIASLFAQLMNISEGDFLIRTQAYTLPFLVLTKNKAL FT IVRIAELSQSDVATLCLTNMHKILASLLTTDHPNLEESVMLLLSLATSDFEKVDLTSLL FT RSDPISITVELLQLYQNDVPHEKIENALRKVAMIVSQVVNDEDLSNKELLYDFFNNHIL FT GILAEFSNILNDLKGKTSINEKIKTIVGIEKMLSLCGGAVKLGLPQILSNLQSAFQNEH FT LRFYAIKAWFSLILATKEPEYSSIAGLSLVILPPLFPYLEPQEAELVIQIFDFISSDTH FT KCLQGLKWAIPTSLDSACFSLKAKEIFCSLQNEDFYSELQSIIKCLTNENEPVCYLGLQ FT KLELFFQAKVDELHDTLNLDISNEVLDQLLRCLLDCCVKYASTNMQISYLAAKNLGELG FT AIDPSRAKAQHIIKETVVLDNFENGEESLKFILDFMQSQLIPAFLVTTDTKAQGFLAYA FT LQEFLKLGGFKSAVINKKKGLTVVTEHWMSLPDLSKRVLIPFLTSKYHLTPIPKIDIRY FT PIYKENVTIHTWMQLFSLKLMEYAHSQNAEKIFGICSKVVKDQEVNIPCFLLPFLVLNV FT ILTESELEVNKVIEEFQLVINQPGPDGLNSVGQQRYTSFVDVFFKIVDYLNKWLRMRKK FT RNWDRRSAIARKENRYMSVEDATSRESSISKVESFLSRFPSKTLGIVSLNCGFHARALF FT YWEQHIRNATAPYAALESDYRVLQEIYAGIDDPDEIEAVSLNFHDYSFDQQLLLHENSG FT TWDSALSCYEIIIQKDPENKKAKIGLLNSMLQSGHYESLVLSLDSFIINDNHEYSKMLN FT LGIEASWRSLSIDSLKKCLSKSNLESFEAKLGSIFYQYLRKDSFAELTERLQPLYVDAA FT TAIANTGAHSAYDCYDILSKLHAINDFSRIAETDGIVSDNLDIVLRRRLSQVAPYGKFK FT HQILSTHLVGYEKFENTKKTAEIYLEIARISRKNGQFQRAFNAILKAMDLDKPLATIEH FT AQWWWHQGQHRKAISELNFSLNNNMFDLVDEHEERPKNRKETLGNPLKGKVFLKLTKWL FT GKAGQLGLKDLETYYHKAVEIYSECENTHYYLGHHRVLMYEEEQKLPVNEQSERFLSGE FT LVTRIINEFGRSLYYGTNHIYESMPKLLTLWLDFGAEELRLSKDDGEKYFREHIISSRK FT KSLELMNSNVCRLSMKIPQYFFLVALSQMISRVCHPNNKVYKILEHIIANVVASYPGET FT LWQLMATIKSTSQKRSLRGKSILNVLHSRKLSMSSKVDIKALSQSAILITEKLINLCNT FT RINSKSVKMSLKDHFRLSFDDPVDLVIPAKSFLDITLPAKDANRASHYPFPKTQPTLLK FT FEDEVDIMNSLQKPRKVYVRGTDGNLYPFLCKPKDDLRKDARLMEFNNLICKILRKDQE FT ANRRNLCIRTYVVIPLNEECGFIEWVNHTRPFREILLKSYRQKNIPISYQEIKVDLDFA FT LRSPNPGDIFEKKILPKFPPVFYEWFVESFPEPNNWVTSRQNYCRTLAVMSIVGYVLGL FT GDRHGENILFDEFTGEAIHVDFNCLFDKGLTFEKPEKVPFRLTHNMVDAMGPTGYEGGF FT RKASEITMRLLRSNQDTLMSVLESFLHDPLVEWNRKKSSSKYPNNEANEVLDIIRKKFQ FT GFMPGETIPLSIEGQIQELIKSAVNPKNLVEMYIGWAAYF" FT misc_feature 15028..15378 FT /note="Pfam match to entry PF00454 PI3_PI4_kinase, FT Phosphatidylinositol 3- and 4-kinases" FT CDS join(complement(17763..18710),complement(15720..17687)) FT /db_xref="GOA:Q9UUM2" FT /db_xref="SPTREMBL:Q9UUM2" FT /label=SPBC216.06c FT /note="SPBC216.06c, len:971, SIMILARITY:Mus musculus, FT G3818539, timeless protein., (1197 aa), fasta scores: opt: FT 258, E():4.2e-09, (25.0% identity in 545 aa)" FT /gene="SPBC216.06c" FT /product="conserved hypothetical protein" FT /protein_id="CAB40166.1" FT /translation="MELDEVIQGIVSAIGGFDYSDDEKVYVLGDEALACLKDLKRYLQV FT VDEKYKVWQIRSLLSSLQLVTNDICPILSDWDKDITNYRNWRIALACVELLVPLTWPLE FT TEHETFRENVDVLYNLRQAQSNYKNSILSYKKGSVLSAILAVLLKPLSTPAESRTLRDK FT GIIRIVLLLFRNILQIDELKTKNETIISFAKAHILDLIVTLVSNLDEFEHFDVYILEIV FT YNLIRGCKPSALFSDASLTNSQTELNSLLLKESTQNRYLKRNAHTRHNRFGTMLSVQTE FT DRRFTIASQNIKTDGLDELDSHKRFRKRGTRRKHFDDINKSFFINTEAGTALRNFAVEF FT LEAGFNPLFQSLLKDLEREDPRVLPIHKMQLLYVQSFFLEFMRFSSKPKKTEEIYSNDY FT SFGLAASVFDQRALIMHNRLMVESFEMKQWSTFQASMLSMTQLLFTLRSMTLCSSEIYQ FT RIADNLLSNIFYQEEILLLVYSALKHFKTQSFGYLDAITELTIVLLKELEKFSSAKQYL FT YVKKRRRNQKSVDSNVLESDEDEESSLINANAAVEDRLFDFGRYESRYCDNGCIDSFVL FT FLQCYQDLDSKQIHRAISFFYRIFVKQKCHVYLYRLDFLRVLDKMFNDHVYFSTTNSAR FT QDFEQFFVYYMRKLSDALKDVPALFIELPFPKLTDTFYYLEYGKSPLFSIHGSRKGPLY FT ETVPGLSHLEKVAAVVACLINENKSDLLDELKVQLNCLISERKLITLADENKYINEGGN FT DGERMGKNLKGDTDSFNTALLKDGKFRLLLELCGFEESDNNIDVQALWKLPNSVIIDEL FT VEHAMLLRRFTDDPPTFEGTKPEDLLVRKQRGNVRLPSSSEGETSDEEIEFEADDPITF FT ANRREALNKITDRKRKKMKTNETIIDHTTRKKKENHLRSAKYIVDSDDDSETDIAFFQS FT EAALREKNAQKASALFKRIDDLEMEGKLQEIEQLSENSSSD" FT misc_feature complement(17688..17700) FT /note="ctaacaatattag, splice branch and acceptor" FT misc_feature complement(17757..17762) FT /note="gtatgt, splice donor sequence" FT CDS complement(19388..25311) FT /codon_start=3 FT /db_xref="GOA:Q9Y7K2" FT /db_xref="SWISS-PROT:Q9Y7K2" FT /label=SPBC216.07c FT /note="SPBC216.07c, len:1973, FT SIMILARITY:Schizosaccharomyces pombe, O14356, putative FT phosphatidylinositol 3-kinase c30d10.10c, (2335 aa), fasta FT scores: opt: 6887, E():0, (53.5% identity in 1974 aa)" FT /partial FT /gene="SPBC216.07c" FT /product="putative phosphatidylinositol-kinase" FT /protein_id="CAB40167.1" FT /translation="SIALGQAFSNYAYDLFDLIFASGLSEASYRALSDLAHNIPPLLPV FT IQERLLDMLSKILSGRPFIPPGCPPQYVARSLKSSKSASLKTGFFPNDVYILALKVLGN FT FDFSGYILNEFVKDCVVVYLENNDPEVRKTASITCSQLFARDPILSQTSDHAIQVVAEV FT LEKLLTVGICDTVPDIRLTVLNSLDSRFNKHLAQADKIRLLFIAINDENFAVRESALRI FT IGRLNVYNPAYVMPYLRKIMLKTLTILDYSTIIRTKEENAKLLCLLIAAAPRLIESHVE FT PILQILLPKAKDSSSIVAASIVNSLGEICQISGEVIVPFIKDLMPLIIEALQDQSSPIR FT RAAALKALGNLSSSTGYVIDPYIEFPSLLDILIGITKTEQDITIRRETIKLIGTLGALD FT PNRHRVLEKGTEKVVPEQKNIPPDISLLMSGIGPSSDEYYPTVVITALMSILKDPSLTI FT HHTAVIQAVMYIFKTMGLRCAPFLSQIIPEFIAVMRTCPTNILEFYFQQLSILVLIVRQ FT HIRSFLPDLFKLIKDFWNPHSNLQFTILSLIESLARAMQGEFKPYLPSLLVMMLQIFDS FT DVSVDSVSTKKVLHAFIVFGDTLADYFHMLLDPILRLYERNDVSIGIKESIMITIGRLS FT MVINLSEYASRIIHPVMRMLSCNNASLIRVSMDTVCALIYQLNVDFAIFIPMIDKCLKM FT NGVTHETYSILVEQFLQEQPLPIKLNPYEKYDKPKLDVVASAADITSKKLPVNQEILRN FT AWEASQRSTKDDWQEWIRRLGVALLRESPSHALRACAALAAAYQPLARDLFNASFVSCW FT SELYDHFQEELVKSIEIALTSPHISPEIIQILLNLAEFMEHDDKPLPIDIRTLGAYAAK FT CHAFAKALHYKELEFIEEELVTKPSVDTIEALISINNQLQQPDAAIGILKHAQQHDKMN FT LKETWYEKLQRWEDALSAYEKREAAGAGNFEITMGKLRCLHALGEWDRLSQLAQENWIH FT AGHDARRYIAPLSVAAAWGLGQWEQMDEYISVMKSESPDKAFFNAIVALHRSQFEEAAS FT YITRARDLLDTELTALVGESYNRAYSVAVRVQMLSELEEIITYKKAEDKPEVREMIKKT FT WVRRLKGCQRNVDVWQRMLRIRSLVISPRDNMEMWIKFANLCRKSGRISLAKKSLNLLL FT EDDENLDNSLVLKKTHPSIVYANLKFLWAVDDKRKALNSMQEFTSQLISDINVDPALFV FT QSTSVNTQKSQEEIQYYFHLLARCYHKQGQWQQEIENNWSEGSFDGVLQSYMYATQFDS FT KWYKAWHSWALANFEAVKFLEQSEEQIPSAAYEQYIIPAVKGFFKSIALSKGNLQDTLR FT LLNLWFKFGNNSNVINTLNVGISTVNIDIWLDVIPQLIARIHASSLSVRKSVHQLLSDV FT GRAHPQALVYPLTVAAKSQSSARQNAALAIMDSLKTHSPRLVEQARLVSHELIRAAILW FT HEQWHEGLEEASRLYFGDHNIEGMFAVLRPLHEMLERGPETLREISFQQAFGRDLVEAR FT DCCIRFEQTGDISDLNQAWDLYYQVFKKIRKQLPQLTTLDLQYVSPKLLHVHDLELAVP FT GTYVSGKPVIRIVKFYPTFNVITSKQRPRRLSIKGSDGKDYQYVLKGHEDIRQDERVMQ FT LFGLCNNLLLADPETFKRLLSIQRYPVIPLSPDSGLLGWVLDSDTLHVLIRDYRESRKI FT LLNIEHRLIIQMAPDYDRLTLLQKVEVFEYALLSTTGQDLYRVLWLKSRSSEAWLNRRT FT NYSRTLAVMSMVGYILGLGDRHPSNLMLDRYTGNIIHIDFGDCFEVAMHREKFPEKIPF FT RLTRMLVNAMEVSGIEGTFRITCEHVMRVLRTNKESVMAVLEAFVYDPLINWRLAPAYS FT PSIDEKQSNEPNTLLGETIDGLHRKRLNEEGITLEERQKPEILNQRAITVLNRVSNKLT FT GRDFKPQQQLDVPSQVEKLILQATSIENLCLCYIGWCSFW" FT misc_feature complement(19772..20425) FT /note="Pfam match to entry PF00454 PI3_PI4_kinase, FT Phosphatidylinositol 3- and 4-kinases" FT misc_feature 25207..25311 FT /note="nominal overlap with SPBC646 S. pombe chromosome 2" XX SQ Sequence 25311 BP; 8182 A; 4574 C; 4481 G; 8074 T; 0 other; atttaacgaa agtagcaaat aatgcagagc aggactggaa ttgtagccct ttagcgatgt 60 tgcaaacctg ctgaataaag aatataccgt cttgcttgcg ttgatcatcc tcgccttcat 120 tcacataaat gctaaacagt tcatgtaaaa atttttcatt tgtttgaagg tattgaataa 180 tatcagcctg gttaaagaag ataaatgaat ttagcaccga aaaggagggt tcgtcaacaa 240 tccttgaaac gacaacatcc cttagatact gaagcttaaa tgtctggtga atttttgcaa 300 gaatccgtgg atcctgaatg ggaaccacct gcttaaactt tttggaatcc attaaatatt 360 cccgatggtt cgctttgata ttggggaatt ccggatcgta ttcgagaata ccagctacac 420 acattagctt ttcatcatta gagaacaacg attcgagtaa aggggcgtcg ttcaattgca 480 ctgacagcga ttagcaagga tttaacgaat ctaaaaagta taaagtagat taacatacca 540 aagcttttta ttatggaaca caatcgatga aggtcatctg tattctctag atcctcacac 600 agaggaaaaa gttcaataag tctatcaata taattttcat ttgaaacata acgaaccaaa 660 ctatctcttg attgaataga ctgcatatat ccatatactg cttcttcaat ttcttttaaa 720 ttagcaagct ctggggctgg aagatcgacc gtgtttaggt agttttcatt aagcgccccc 780 tcatccgtca atatatcatc gttggagtaa cttctagtta ccgatgatat tgccttttga 840 acatttgcta aaaacatcca catgtctata caaccgctag attcttgaaa gcttaaagca 900 agatcagtac cattcaattc ttgccagact atgagagttt cttcttgacg gctgtatata 960 tcttccgcaa tcaattgtgt tttcaaaagg atggtttcat tatcagcttc tgaacgcaca 1020 atgaaataag ccaacggtcc ctctattttt ccatcgcaat aaccggtgcc acagtctacc 1080 cagttttcat cttccatttc gtacactttt acacgtctgg gaatcgatgg cacttcgatc 1140 ttctgcaatg cagctgcaat tgcttcgtct aattcctctt cttcattttc tccatctgaa 1200 atttcatcaa tattattatt taaatcttcc tcttccttcg tagaatccat ttctacggcg 1260 gattaagggt agacgtcagc ttcgaattta cgacgttggc gttcgtcacc aaattttcaa 1320 aagtgaagac gaaattcaaa cgtggtggtg aatgaatgca ataccgtaga ttgcaccaag 1380 attgtaatta ttaataaatg tatttctcat taaatggcaa tgccgcttta cttaattatt 1440 tggtttgcct aaaatataac aaatagattt gttaagcagt gtactatgta tatttcacgt 1500 gcataatttt gaagtgttat ggcagaatta tgttctttat agagtcaaat aactattata 1560 tacgtgatcg tggtgctttc agtcactatt tttcattgta attcggtatc tgtttacaac 1620 aatatcatta acggacgtta tgcattttaa cgatgagtac ttcaccgctc ggtgtatatg 1680 ctgtaatcaa tccttatatc gagttgtgtt ttaaacgttt tatactgtct acaattagca 1740 tttaaatctt ttcgaaatag taaataaact aaatatgaat ataaataaag ttaattattg 1800 tctaaacaca tgtgtagcct cgtcaaatca attttttgca agtcaatcat gaggctcagg 1860 gtacatttgt aaagtaatag ttaattttta agtacaaact aatggtattt ataccgatat 1920 atatattgaa agctgctaaa gcttcgctag atattcaagt actctagcaa atgcatcaat 1980 ataaatacag tttttttgct tttactaagt tttattgtta aagcgtaata cgagaaattt 2040 gccaaatgag aacacgaatt gaattgatat aattccagaa ataaaaatta tgtattcaag 2100 acgatgactg ttgcgatatg catgcttacg agtttatcga tatataaaag acaaagagag 2160 ttgagcttac caaaacatat actgatcctt catggagaaa aaacaagata acgaggtgga 2220 attatattca attgatttaa aaaatagaaa tgaaagtgca aaaataaagc ttgcttatgc 2280 gaaagcgtta gaggaaagca ttctttgtga aacacgaaaa atcgaacaag aaattaaaga 2340 ccaagtggtt caaaaggaaa ataaaacata ttttaataac aaatttgata atcgatataa 2400 attacgcgac ttggaaaaaa atttagcgga ggaggaggtg agaattacgg agatgcttac 2460 tattcaacgt caagacattg caattgaaag aaggaagaac acaaattgct tcagtgagtc 2520 ttctcaagta gatcaatatt cagttactga aaccaatcta caatatgcta ctaacattgg 2580 cttaaacctt ctgcaacagt tgcggtattt aaggctgcaa ctgtcagaga aagaagattt 2640 gcataaaaag ttgtcagtgg ataatgccca tttaatcaag caacttgatc tactttcttc 2700 aaacatgaaa acacttatga aagagaagac taaggtgcaa ggacaaaggg atttgcttga 2760 acaaagacta caaggattaa tgaaaaaatt gacagaagta gagtctttga ccgtttcact 2820 taacgatgag aagaacaaac tgacattgga attaacaaat ttaagaattt gccttcacga 2880 gcttcaactg aatgccgaaa aaggcgaaac tatagatgaa agtgaagatt ctaaaaatac 2940 tttggtaact gaggatgaaa acgacgattc tgtatttttg gagtcttcct cggataagta 3000 ttttgatagt tcatcttttg atgcggagca agaagagaaa cacgattttc caatagatcc 3060 ttttttgtcg ttggaatcca atgtacaaac ttcggtatct caatcatcgg ccgttctcaa 3120 atccatcaat ttagcaaaac aggagttagt gagtgtaaat catttggtag ctgacgatac 3180 taaaacaccg tctccaaatt tatcatcgga aataattgaa aacacaaaag ctgacataaa 3240 gaaatcaatc aggtctctga acaaggcagt atcaccagaa aactctatag acatcgaaga 3300 tgaaaccgac agagatgatg agtttatttg cttccttttg tcttatcagc aactacaaaa 3360 ggcgctgaaa agtaacttgg gcctttttca gctttcttgc ttgtacccac tttctctgaa 3420 tcatcttatt cagtcattct ttcaatctct cacctctcaa atttcaataa aagatattga 3480 ctcaaaaaat aaacaagtca ttaaactttt caaaccgact aaaagctcag atcgccagga 3540 aatttttgaa ttggctcaat ttgaacctcg ccaaaaattt cctatagata cgaattcttc 3600 aaaatgcgac atgtctgcaa gtactgagat gcatttgaaa gatactgaaa aatttgctaa 3660 tttcaaacta aaagaaaaca ttttaaatca ttcttctatt tacgaacgtg atgtttctta 3720 cctgcctgca ttaaacaaag gtggacgtga aaattattta aacaatcgcg tctcctctta 3780 taggcttgtt aaacctattt taaattccta tggaaatcat gtattaaacc gtatacaaca 3840 tgatattctg gagaatcact tctgttgtct aaaaaatgtc aaagactttg tatgtggtgc 3900 aaatacaatc tccatgcagt ggaatctgca aaagaatatg gaatttatca gctctgtttt 3960 ttccttaata aaaaatgaag taaatgacac atcagctaat agtgtcattc taaggaccga 4020 tgcgctttca aatgttgcta ccacgaggtt gaaaagaaaa ttaactagcg ctattattga 4080 ctgctcgatt cctcgtcgga ggttgcgcca ctatagtaat ccagaaatag ctgaatttaa 4140 gaattttaga ttatctacgg atatttccca cagtaatgtt aggaattcga aaaagctatg 4200 ttccaatgga tctatgaatt gtatgaggca aggcaaggca gtttttcctc gaaagatccc 4260 atatcaagag catgactggg aacaatggga aaaaattgct caatcctcga tgtttaagaa 4320 tcgttcaatt gcttcacgtc aatcattgga aacttctgat gttactttgg acattaatat 4380 gtcttcaaga cattcaaacg gaacttcctc aatgcttttc aaagacttta caaaacataa 4440 taattgggag gcgtcaactt atccgtctgc acctaagaat actcgtactt atccaacagc 4500 tgaagttgaa aaaactcggc atgattcctc gcaatcagca cgtcaattga aagcaagaag 4560 tacggctacg acgatttcta tttccttgtc gacggtgtca gacgtattca ccttacctcg 4620 caataatctc aaaagcaaaa caaatacgaa aaaatgcaga gataatttga atctatcagg 4680 tttatcttct tcaacttgta atgcaaattc tgtgaacaaa ttgatgaaac atgtcatgat 4740 gggaaacgaa atgatgaagt acccgagaag tgagagtttc aaaatgttta aaaagagtca 4800 ttggcgctat ttttggatta acccgcattg tgaaatgctg tgctggtcta aaacaaatcc 4860 atttattgaa aaaggaagga aaaatcaagt caagtctgtg aaaattaagg gaatgactat 4920 tataaaagcc ccagatgcct taaagaacgc caatttacat aatgaagtta ttgtgatgca 4980 gacaactgat aagcccatcg tcttaaaagc gaaaagcaag aaaattcaca atatctgggt 5040 tcaagctatc aaacaaataa atcataaggc tatctttgat actaagcccg gcatttaagc 5100 atgtttcagt cattgcttat aagttttaaa gtaaactgtt tcaatattcc ctaacaactt 5160 ttaaagttat accaattgtt tttattaagc ggcatcaaat agaaagatat taaaccactg 5220 taaacaacta agaatcaaat gtcttaatca gttttgtaaa tgaggtttat acgatcaagc 5280 tttattgcaa ttcgacatgc actaatgagg atgatatact ttcctatttt gtcgaaaaaa 5340 ttgctctttc tatacaattc atttttaatc aatcaattta tcatacgaga catttaaata 5400 gcaaacaaaa gacgactaac gtttaaaggt aacatcgata atgttagttt tatcaaaaca 5460 aattatcccg tataagcaaa agaagattca gacttaacct tgacggagtt ttatgtgcaa 5520 agaattaaac attgctatta ctggtaaaca taacaaatct gggcgacttt caattactga 5580 atgaataata agcaacctgt taaatgattt tagtgcccag atgcactttc cgtgtattac 5640 cccaagaact tttagcgaaa gttaaaaaga gcacaatata tctggctagt tattttactg 5700 catcgttaca tcatgttaaa actattagag cttaccatac aaaaactgaa aacgtcacat 5760 aattaactcg gtactactaa ttaggtaaac cgtgcttttg ctcattccct gtggtgtgtc 5820 tcttcgattc aattttgtag attgttttca ttttccttat tcctttcttt ttttaagagg 5880 ggtttgacag atacacagca tttccaattc taaaaattac tcattttaac aattgccatt 5940 gcttttattc aaaggatcag ctaattaagt tcctttttca ataagggaga aggatatatt 6000 ggattcttga ttcccaacgg ttaaagaaat catcgtcagc atttttattt tgtaagaaat 6060 gactgttttt gttgtttttg gagggcatgg aaaggtggcc ttgcttttta ctaaaattgc 6120 tacagaagct ggccatatag tttacaatgt tgtacgtgat tatgttcaga atgaagacat 6180 tgaaaaagtg catggcagaa cttctgtctg ttcacttgag aaggcgacgc ctaatgatat 6240 tgctcagttt ttagctgaaa tacaccctga tgttgttata tttgcagccg gtgcaggagg 6300 taaaggcggc cctgaacgaa caagagccgt cgattatgaa ggtgctataa aagtttatga 6360 tgctatgagg atagctggta ttcgacgctt aattatgata tctgcgatag ataatcgtga 6420 tatgagccaa cctcctcctc cttactatac ggctgctgat atagagctaa gtgagaaaat 6480 acatcagtca attggaactt attaccatta caagtaccta gcggatcagg aattagtgcg 6540 acgctctagt gatattgatt ggacgatttt acgtccttct ggtatgacag acgagaaggg 6600 ttctggaaaa gttgcattgg gtaagatatc cataaattgt atgatgtctc gtgaaaacgt 6660 cgcgcgtact gtactactgt tcgctcttga taatcagtcc atccatttgg tggttgacat 6720 gacggatgga aatgtgccaa tatataaagc cattgctgga ttcgtcgtaa aaggagaatc 6780 atcctatact tattcagtat aatgtaatga cattttcgga tccttcgcgt attattgtag 6840 tccacgcatc ttttactcct ttcttaaaat cttctgaaaa aagaacgaaa atttttcaat 6900 gacctatgaa gcgtacgcaa attaataaat atttaagtga gggatacttt agttataccc 6960 tttatagttg aaataaatgg aagatcatat caggtagtgt aaacattgtg ttatcgttta 7020 ttaactttgg cataagcagc ttagttataa catacggcta gtaaatctaa tttctgacct 7080 agagattact acactctttg aaaacaaaat atattagttt aaaatgttaa aagtaaatgc 7140 attttattga agttaaccaa aacgtgaaca agcaacttta aataaaataa tagccgtaca 7200 tcaagcacaa acaattcgaa ctggtgctaa catctaataa agaaaataca gaaatattaa 7260 gcataatcta gttcaattgt catttgttgc ctcattatgg aattccaaac tcgccgaatt 7320 tatacaatgg cgttcgtcag taggattaga ataaccttct cctttaaaaa tatggcctaa 7380 atgaccacca cagttggcac aaactgcttc tacacgatgc attccataag agttgtcttc 7440 aatgcgtttc acctttccag gtaaattatc gaaaaacgca ggccatccac aatggctttc 7500 aaactttgtg ctagctttat aaagaagctc tttacatgca gcgcaaacaa aaacgccctg 7560 tttagggaac tgatgagtga atcgtcctgc acctgggtgc tcagtaccct tttgtctcat 7620 aattcgatac ttctcaggac ctagctcctt tttccattca tcttcgcttt tttccaatgg 7680 aaatcccatc tttgtattat ttttgacgtt ttggacaggg taggagacgt tatatgcacg 7740 tttcaaaaga ttcgtaaact tcgtatttcc acagattgaa aagtgtgtag taatcacttt 7800 tttcatgaaa acacaagacg atatgtacca caactggcac tacaaaaatt ttcaagtaag 7860 taaacgactt tttgaccact atttatgtga ataggtaggt accaagtaaa aactgcttag 7920 taagtataaa acacagaaga atccgcgatc tagtgaacca atgccctgcg tatgacgctc 7980 cactgacgct atagtcaatg agaactagga tgtgcgatta taacttatct tttcaatatt 8040 ttcttattat ttatttaaga aataattgaa ttaaaactca tttcttcttt tattagccgt 8100 aaaatagctt attttctctc ctactacctt tcaacaataa cttttttttt tgtttattga 8160 ccattataat cacatcaaaa gtcaaaaaat tcaatcatta tcagaaacat ccagcctaat 8220 attacttaaa agttagtttc ctctgaaaat tcagtatcac aaaagctcgt taattagcat 8280 cgctcgatac ttagtgcacc atgcatcttc ctttacctcg tgagtggaaa tcgatttgat 8340 aatcgattgc cacttttcgc ataattctat tgagatattt tattacttac aatcgtcttt 8400 tataaatgct caagactttg aacgcgcgtg ttgcgtttta aaaaggcctt tttttgaatt 8460 gaatcaatgg tttgatatag tatgagccaa cacgcaaaaa ggaaagctgg gtcactcgat 8520 ctttcaccca gaggcttaga tgacagacag gctttcggac agcttttgaa agaagtatta 8580 gcattagaca aagaacatga gttaggtaga agtaattctt taccatctat gacctccgag 8640 cttgttgaag ttttaattga agttggtctt ctagctttta aacatgatga ttcaaaatct 8700 gaatttatct ctcctaagat gctaaaagaa gcccatctct ctctacaagc gttaatgcta 8760 atcttaaaaa ggtctccgac agttttgcgg gagattaaat catctgttac tcttttggat 8820 tggattttac ccaggactat atcattgttt gctgatattc gttttattaa gttatttgac 8880 tcattaaaag agtttcataa gctaatttat cagctaatca gtgaaaagtc attcctatgg 8940 gacttatatg cttcgtttat gcgttattgg aaatattata ttacaaacgt ttcttctata 9000 gttctccaaa tcactaatgc tacattccct tacaagatgc cctcacccaa ttctcaacca 9060 ttgcagagta tcaccccaaa ttatccaacc catcgagagg acaaatttga tttacttatc 9120 attaatatag aggaggcttg tacatttttc tttgaaagtg cccatttttt tgcacaatgc 9180 tcatatttaa agaaatccaa ttttcctagt ccacctctct ttacagcgtg gacttggatc 9240 aagccatgtt tttttaattt tgttatttta ttaaaacgaa tcagcatcgg agactcacag 9300 ctctttctac atttgcattc acgtatagtc caaactttat gctgtttttc cttgaatttt 9360 atatatcatg gccttcccat ttgtgaaaaa tctaaacata ttttaatgtc ctccatcaac 9420 ttaacattgg gatcattgaa gaaaacttat acagttgcta atactgctat atctcttttt 9480 tttctctctt tatttgtttt acccaaaact gtagctggtc tattctatcc ttttggggtt 9540 tccttacttt ctgacttcaa ggtattagag caacttgaac cagattctga tctcaaaaag 9600 gcaataatat tatttaagtg cagataccaa agttcagaaa tagatcaaac aactctccgt 9660 gcttttggcg aaatttgtac tggtaaactt gaaaacacgt tgttttctaa ctctgaatta 9720 aacctttttc ttttacatta tctttccttg gacaatgact tgtcaaatat tcttaaagtg 9780 gatttccaga atggtcataa catatgtaca tttgcaaaat ggtgtataaa caacaactta 9840 gatgaaccgt ctaatttaaa gcactttcgt gaaatgttag attattatag ctctcataat 9900 gttacaataa gtgaggacga cctgaagaac ttctctttag ttttgtgtac tcatgttgca 9960 aaggtgaatg agaaaacaaa tagtattttc cgcacatatg aagtacatgg ttgtgaagtt 10020 tgtaactcat tttgtttact atttgatgag cggtcgctct ttaaaattcc ttatcacgaa 10080 ttgttttgtg cattgctaaa aaatcccgac ataatttcct cttctgttaa acaatcattg 10140 ttgcttgatg gcttttttcg gtggagccag cattgctcaa actttaataa agaatcaatg 10200 ttaagtttaa gagaatttat tatgaaagca ttagccagta cttcaagatg tttacgtgtt 10260 gttgctgcaa aagttttgcc cattttcatt aagggaccta ataatcttga tatagttgaa 10320 tttcacaagg aaagtaaagc cttgattttt aatacgttga aaatattggc ggtggaaaat 10380 acagctattt tagaaacggt cattctttcc tggatctcct tatctagagt ggtagaagaa 10440 gaagaattac attttgtact attggaagtt atatcttctg tgataaacag cggaatattt 10500 tatcaaggca ttggtctcag cgctctgcaa caaattgcct cgacgcgtca tatatccgtt 10560 tggcaattac tttctccata ttggccaaca gtgtccgttg cgattgtcca aggtatgggt 10620 aaaaaaccga acatagccag tttatttgct cagcttatga atatttccga gggcgatttt 10680 cttattcgaa cacaggcgta cactttacca ttccttgtac ttactaaaaa caaagcgtta 10740 atagtacgta tagctgaact ttcacaaagt gatgttgcta ctttgtgcct taccaatatg 10800 cataaaatcc ttgcttcgct acttactacg gatcatccta atttggaaga gagtgtgatg 10860 cttcttcttt cactggccac ttctgatttt gaaaaagttg atttaacgtc tttgttacgc 10920 tctgatccta tttctattac tgtggagttg ttacagcttt atcagaatga tgttcctcat 10980 gaaaaaattg aaaatgcttt aagaaaggta gcaatgattg tctctcaagt ggttaatgac 11040 gaagacttga gcaataagga attactttat gattttttta ataatcacat tttgggtatc 11100 ttagcagaat tttctaatat ccttaacgac ctgaaaggaa agacttcaat taatgaaaag 11160 attaagacaa ttgtcggcat tgaaaaaatg ttatctttat gtggaggtgc agtcaaactt 11220 ggattaccac agatactttc taatttacaa agtgcttttc aaaatgagca cttaaggttt 11280 tatgcaatca aagcttggtt cagtttgata ttagcaacca aggagcccga gtatagttca 11340 attgctggtt taagtcttgt aattttacct cctttattcc cttatttaga accacaagaa 11400 gcagagctag taattcaaat atttgatttt atttcttctg acacacacaa gtgcctacaa 11460 ggattaaagt gggctatccc caccagtctg gattcagcgt gctttagcct taaggctaaa 11520 gaaatattct gttcgcttca aaatgaagat ttttactctg agcttcaaag tataattaag 11580 tgtttaacta acgaaaatga gccagtttgt tatttaggtt tacaaaaatt agaacttttt 11640 tttcaagcca aggtggacga gttacatgac acactaaatt tggacatatc caacgaagtt 11700 ctggaccaat tactaagatg ccttttagat tgttgtgtaa aatatgcttc aacaaatatg 11760 caaatatcat atcttgctgc aaaaaatctt ggtgaattgg gtgcgataga tcccagccgc 11820 gccaaggctc aacatattat taaagaaaca gttgttcttg ataactttga aaacggagaa 11880 gaaagtttga agtttattct agattttatg caatcgcagt taattccagc tttccttgtt 11940 actactgata ctaaagcaca aggttttctt gcctatgctc tgcaagagtt tctaaagctt 12000 ggtggattca agtccgcagt gattaataaa aaaaagggac taactgtggt aacagaacat 12060 tggatgtctt tgcctgattt atccaaacgt gtgcttatac catttttaac ttccaagtat 12120 catttaacac caatccccaa aattgacatt cggtacccta tttataaaga aaatgttact 12180 attcatactt ggatgcagtt gttttctctt aaattgatgg agtacgccca ttcgcaaaac 12240 gctgaaaaaa tatttggtat ttgttcgaaa gtagtgaaag accaagaggt taacattccc 12300 tgttttcttc ttccctttct tgttttaaat gttattttaa ccgagtcaga actggaagtt 12360 aataaagtca ttgaagaatt ccagcttgtt attaatcaac cgggacctga tggattaaat 12420 tccgtggggc aacaaagata cacctcattt gtagatgtat tttttaagat tgtggattac 12480 cttaacaaat ggcttcgcat gcgaaagaag aggaattggg atagacgttc tgccattgca 12540 aggaaagaga accgttatat gtcggtggaa gatgctacct ctcgagaatc atcgatctca 12600 aaagttgagt catttctttc tcgatttcct tcaaaaacat taggtattgt ctctttaaat 12660 tgtggatttc atgctcgtgc attgttttat tgggagcaac acatacgtaa tgctacagct 12720 ccatatgcag ctttagagtc cgattataga gttttgcagg aaatatatgc tggaattgat 12780 gatccagatg aaatcgaagc agtgtcttta aatttccatg attactcgtt tgatcaacaa 12840 ctccttttac atgaaaattc aggaacatgg gactcggctt tgagttgtta cgaaattatt 12900 attcaaaagg atcctgaaaa taaaaaggcg aaaatcggtt tgcttaacag catgctgcaa 12960 tcggggcatt atgaatctct tgttttgagt ttagattctt ttataatcaa tgacaaccac 13020 gagtattcga agatgttaaa tttgggtatt gaagcttcat ggcgttcgct atctattgat 13080 tcgttaaaaa agtgtctttc aaaaagcaac ttggaatctt tcgaagctaa attgggtagc 13140 atattttacc aatacctacg gaaggattct tttgctgaat tgacggagcg gctgcaaccc 13200 ttgtacgttg atgctgctac agcaattgca aacacaggcg cccattcagc ctatgattgt 13260 tatgatattt tatctaagct gcacgcaatt aatgacttta gtaggattgc tgaaactgac 13320 ggaattgttt ccgacaatct tgatattgtt cttcgccgtc ggcttagcca agtagctccg 13380 tacggtaaat tcaagcacca aatcctgtcc actcacttag ttggctatga aaaatttgaa 13440 aacacgaaga aaactgctga aatatatctc gagattgcaa gaatatctcg aaaaaatggt 13500 caatttcaaa gagccttcaa tgccatcctc aaagcaatgg atttagataa accgctagca 13560 acaatagagc acgcacaatg gtggtggcat caagggcaac atcgtaaagc tatttctgaa 13620 ttgaattttt cgcttaataa caacatgttt gatttggttg atgagcatga agaaagacct 13680 aaaaatcgta aagaaacttt aggaaatcca cttaaaggaa aagtgttctt gaaacttaca 13740 aaatggctcg gaaaagctgg ccaactggga ttgaaggatt tggagacgta ttatcataaa 13800 gcggtagaga tttactcaga atgtgagaat acgcattatt atcttggcca tcatcgagtt 13860 ttaatgtatg aagaagaaca aaagctccca gttaatgaac agagcgaacg atttttaagt 13920 ggtgagttag taactcgcat aattaacgaa tttggtcgat ctttgtacta tggtacaaat 13980 catatatatg aaagtatgcc aaaattgctc acactgtggc ttgattttgg ggccgaagaa 14040 cttcgcttat ctaaagatga cggcgaaaag tactttcgtg aacacattat ctcttcgaga 14100 aaaaaatctt tggaacttat gaattcgaat gtttgtcgcc tttctatgaa aattcctcaa 14160 tacttttttc tggttgcatt atcccaaatg atatccagag tatgccatcc aaataataaa 14220 gtttataaaa ttttggaaca tataattgca aacgttgtag catcttatcc tggggagacg 14280 ctatggcaat taatggcaac aataaaatcg acttctcaaa agcgctcgct tcgtggaaaa 14340 agcattttaa atgttttaca ttctaggaag ctttctatgt cttccaaagt tgatataaaa 14400 gcactcagtc aatctgcaat tctcattact gaaaagttaa tcaatttgtg caatacaagg 14460 attaacagta aatctgtaaa aatgagctta aaggatcatt ttcggctttc ttttgatgat 14520 ccggtagatt tagtcattcc tgctaaatca tttttagaca ttactttacc agctaaagat 14580 gctaacagag ctagtcatta tccatttcca aaaactcagc ctactctgtt gaaatttgag 14640 gatgaggtgg atataatgaa ctctcttcaa aaaccaagaa aagtgtacgt tagaggtacg 14700 gatggcaact tatacccatt cttgtgcaaa cccaaagatg atcttcgtaa ggatgctaga 14760 ttgatggaat ttaataatct tatttgtaaa atattgagga aagatcaaga agcgaacaga 14820 aggaacttgt gtattagaac ttatgttgtt attcctttaa atgaagaatg cggatttatc 14880 gaatgggtaa atcatactcg tccatttaga gaaattttgt taaaaagcta tagacagaaa 14940 aacattccca tatcatatca agaaatcaaa gttgatttag actttgcact gcgaagtcct 15000 aaccctggtg atatatttga aaagaaaatc ttaccgaaat ttcctccagt tttttatgag 15060 tggtttgttg aatctttccc agaaccaaat aattgggtta ctagtagaca aaactattgc 15120 cgaactttag cagtaatgtc aatagttggc tacgttttgg gtttgggaga tcgccatggc 15180 gaaaacatat tgtttgatga atttacaggt gaagctatcc atgtcgattt caactgtctt 15240 tttgataaag gtcttacttt tgaaaaacct gaaaaggtgc cgttcagatt aactcataat 15300 atggtagatg caatgggtcc gacaggttat gaagggggtt tcaggaaagc tagcgaaata 15360 acgatgcggc ttcttcgctc aaaccaagat acattgatga gcgtactaga gtctttccta 15420 catgatcctt tagtcgagtg gaatagaaag aagtcgtcaa gcaagtaccc gaataatgaa 15480 gcaaatgaag ttttggatat aattcgcaaa aaatttcaag gctttatgcc aggggagacg 15540 atacctttat ctattgaagg gcaaattcaa gaattgatca aatctgctgt caacccaaaa 15600 aacctggtag aaatgtacat tggttgggct gcttatttct agcattttac taacaaaaat 15660 ttcaatgaac aagctaccca ttattaaact tatgatttga atcgaagata ttttatttat 15720 taatccgatg aagaattctc gctgagttgt tcaatttctt gtaattttcc ttccatttct 15780 aaatcgtcga ttcgcttaaa tagggcactg gctttttgtg catttttctc tcgtaaagca 15840 gcttctgatt gaaaaaaagc tatatctgtt tctgagtcat catccgaatc aacaatatat 15900 tttgcagatc gtaaatggtt ttcctttttc tttcgagttg tatggtcaat aatagtttcg 15960 ttagttttca tctttttacg ttttctgtca gtaatcttat ttaacgcttc tcgacgattg 16020 gcgaaagtta taggatcatc tgcttcaaat tcaatttctt cgtcagatgt ttcaccctca 16080 ctacttgatg gtaaacgaac atttcctctt tgcttcctca ctaataaatc ttcgggcttg 16140 gtgccttcaa acgtcggcgg atcatcagta aaccttctca acaacatggc atgctcaaca 16200 agttcatcaa ttataacaga atttggtaat ttccatagtg cttgaacgtc tatattgtta 16260 tctgattctt cgaatccaca taattctaat aatagacgaa attttccgtc tttcaaaagg 16320 gccgtattaa atgaatctgt gtctcctttc aaattcttcc ccattctttc accatcattt 16380 ccaccttcat ttatatattt gttctcgtca gctagcgtta ttagctttct ttctgaaatg 16440 aggcaattaa gttgaacttt caattcatct aataaatcac ttttgttttc atttataagg 16500 catgcaacaa cggcagccac cttttccaaa tgtgataagc caggcaccgt ctcgtataac 16560 gggccttttc tcgaaccatg aatagagaaa agtggacttt ttccatattc cagataataa 16620 aatgtgtcgg ttaattttgg gaaaggcaac tcaataaaaa gtgctggtac atcttttaat 16680 gcatctgaaa gctttcgcat ataatataca aaaaattgtt caaaatcctg tcttgctgaa 16740 tttgtagtag aaaaatagac atggtcatta aacattttgt ccagaacacg taggaaatcg 16800 agacgataca aataaacatg gcatttttgc ttcacgaaaa tgcggtaaaa aaaggaaata 16860 gccctatgaa tttgttttga atccagatct tggtaacatt gaaggaacag cacgaaacta 16920 tcaatacatc cattatcaca gtacctagac tcatatctgc cgaaatcaaa cagacggtcc 16980 tcaacggctg cattagcatt aatcaagctg ctttcttcat cttcatccga ttccaagaca 17040 ttgctatcaa cagatttctg atttctcctt ctctttttca catagagata ttgtttagca 17100 ctgctaaatt tctcaagctc ctttaatagc actatagtta gctcagttat tgcatctaaa 17160 tacccaaagg actgagtttt aaaatgcttt aaagcgctat aaacaagtaa aagaatttcc 17220 tcttggtaaa agatattgct tagtagatta tcggcaattc tttggtaaat ttctgaggaa 17280 caaagtgtca tacttcgaag agtgaaaagt aattgagtca tcgaaagcat ggatgcttgg 17340 aaggtgctcc attgtttcat ttcaaaggat tctaccatta acctgttgtg cataatcaaa 17400 gctcgttggt caaaaacgga ggctgctaag ccaaaactat aatcattaga gtaaatttct 17460 tctgtttttt ttggtttaga cgaaaatctc atgaattcca aaaaaaatga ctgaacgtat 17520 aataattgca ttttatgaat tggaagcaca cgaggatctt ctctttccaa gtcttttaag 17580 agagactgaa ataatggatt gaatccagct tccaaaaatt cgacagcaaa gttccttaat 17640 gcagtacctg cctcggtatt gataaagaac gatttgttta tgtcatccta atattgttag 17700 aatagaatag ttgaattgga aaaaaaaatt taaacaaaca tcgtgtttaa ctaagtacat 17760 acaaaatgtt ttcgacgtgt tcctcgtttt cgaaaacgct tatgagagtc aagctcatca 17820 aggccgtcgg tttttatatt ttggctagca atagtaaatc ttctgtcttc agtttgaaca 17880 gaaagcatgg ttccaaatct attatgcctc gtatgtgcat ttcgtttcaa atagcgattt 17940 tgggtcgact ctttgaggag taagctatta agttcggttt gagagttagt caatgaggca 18000 tcagagaaaa gggctgatgg cttacaacct ctgatcaagt tgtagactat ttctaatatg 18060 taaacatcaa aatgctcaaa ttcatcgaga ttcgagacca gtgtgacaat caaatctaat 18120 atatgagctt tcgcaaacga gataattgtt tcattttttg tttttaattc atcgatttga 18180 agaatgtttc gaaatagtaa cagcactatc ctgattattc ccttgtctct aagtgttctg 18240 gattctgcgg gagtacttaa gggctttagt aaaacagcta aaatggcgga taaaacgctc 18300 cccttcttgt aagataaaat tgaattttta taatttgatt gagcttgacg cagattatag 18360 agaacatcaa cattttctct gaatgtttca tgctcagtct ccaaaggcca tgttaatggt 18420 acaagaagct caacacaagc taaagcgata cgccagtttc tgtaattagt aatgtcttta 18480 tcccagtcag agagtattgg acatatatca ttagttacca actgtaagct cgagagcaaa 18540 gatcgaattt gccaaacttt gtacttttca tcgactactt gaagatagcg cttcagatcc 18600 tttaggcaag ccaaagcttc atcaccaaga acgtacactt tttcatcgtc tgaatagtca 18660 aatcctccaa tggcagaaac aatgccttga atcacctcat ctaattccat tcaagttgat 18720 ttgttaaatc aaaagctctc aagttccttt tttttgtatt gtcggtatgc gtcgataaat 18780 aaaccaaatt taagaaatta aataaatttt aataattaag cgatattaat tatgttcatg 18840 aataatcgta ttcttttaag ataagtaaat ttgattgtag atacgtgaag aggggtggtg 18900 acagtaaaca atgaataata aatttttaaa acaatattta acttttcaaa ataacttgga 18960 tttttaaaaa aatgtgtgta aagtaaaaca ctttataatt taaatcgcat taaaatggca 19020 ttcagtatta tattataaaa ttcgataata tggactcaac aaaacgaatt tgctacctaa 19080 cttgtacaat gcataattag aatttagttt caataatttt cacaatttca gatgtagaaa 19140 tttagagttt attattttca gaatgattaa gcagcaaatc tttaataaca atataaagag 19200 atgcattctc tactacaaaa ttctaaaaat tctgcgtcaa attcaacatt tcctctattt 19260 tgtaaaattg taaaacaacg taataaattg ttacaggact cattcataaa gactatttac 19320 actttattta atatagaata tatatatgat gcggcagaaa agcaatttga acgtttggga 19380 ctgtcaccta ccagaaacta caccagccaa tatagcacaa gcataggttc tctatagagg 19440 ttgcttgtaa aatcagcttc tctacttgac ttggtacatc caattgctgt tggggtttga 19500 aatcccgacc agtaagttta ttggacacac gattaagaac ggttatagct ctttgattga 19560 gtatctcggg tttttgacgt tcttcaagtg taattccttc ttcgtttaag cgtttccggt 19620 gtaaaccatc aattgtctca ccgagaagtg tattaggttc gttagattgc ttttcatcga 19680 tagaaggtga atatgcagga gcaaggcgcc agttaataag aggatcgtaa acgaaagctt 19740 ctaaaactgc catcacagac tccttattag tacgaagaac tcgcataaca tgttcgcatg 19800 ttatccggaa cgtcccctct ataccactaa cttccattgc gttaacaagc attcgcgtaa 19860 ggcggaaagg aatcttctcg ggaaactttt ctcgatgcat tgctacttca aaacaatctc 19920 caaaatcgat atggatgata ttacctgtat acctgtccag catcaaattg gaaggatgac 19980 gatcgcccaa acctaagatg taccctacca ttgacatcac cgcaagagta cgagaatagt 20040 tagttcgcct attaagccaa gcttctgagc tacgactctt cagccataaa acgcggtata 20100 aatcctgccc cgtagtacta agtagggcat attcaaagac ttcaactttc tgaaggagag 20160 tgagacgatc gtaatctgga gccatctgaa tgatcaacct atgttctatg ttgagtaaaa 20220 tctttctgct ttctctgtag tcacgaatta agacatgcaa agtatcgcta tccaaaaccc 20280 agcctaaaag gcctgaatcc ggtgataaag gaatcactgg atacctttgg attgaaagta 20340 agcgcttaaa agtttccggg tcagctagta acagattgtt acaaagccca aatagctgca 20400 taacacgttc atcttgtctg atgtcctcgt gaccctttaa aacatattga taatcttttc 20460 catcactgcc tttaatactc agtcgtctcg gacgttgctt agatgttatc acgttgaatg 20520 tagggtaaaa ctttacaatt cttataacag gtttcccgct aacgtatgtt cccggaacag 20580 ctaactcaag atcatgtaca tgtaagagtt taggagaaac gtattgtaaa tctaatgttg 20640 tcaactgagg tagctgttta cgaattttct tgaaaacttg gtaatataag tcccaggcct 20700 gatttaagtc tgatatatca ccagtttgct caaaacggat acaacaatcc cttgcttcga 20760 ctaagtcacg tccaaaggct tgttggaaag aaatttcacg aagcgtttcc ggaccacgtt 20820 ccaacatttc atgcaatggt ctcaacacgg caaacatacc ctcaatgtta tgatcaccaa 20880 aatacaatcg tgaagcctct tccaatcctt catgccattg ttcatgccaa aggattgcag 20940 ctctgataag ctcatgacta acaagtcttg cttgttcaac tagacgtgga ctatgtgttt 21000 tcaaggaatc cataattgct aaagcagcgt tttgcctagc agaactctgc gattttgctg 21060 ctacagttaa aggataaaca agagcttggg gatgcgcgcg acctacatcg gaaagcaact 21120 gatgcacaga tttacgaaca ctcaaagagg aggcatgaat tctcgcaata agctgaggta 21180 taacgtccag ccagatatcg atgttcacag tggatatacc aacgttcaaa gtattaatta 21240 cattgctatt attgccgaat ttaaaccaaa gattaagaag gcgcaaggtg tcctgaaggt 21300 tacctttgct taaagcaatt gacttaaaaa agcctttgac tgctggaata atatactgct 21360 catatgcagc acttgggatt tgctcctctg attgctccaa aaactttaca gcttcgaaat 21420 tagctaatgc ccaagagtgc caagctttat accatttaga atcaaattgc gtagcataca 21480 tatatgattg aagaactcca tcaaaagatc cttctgacca attattctca atttcttgct 21540 gccattgacc ttgcttgtga taacatctag ctagaagatg aaaataatat tgaatttctt 21600 cttgtgattt ttgagtatta actgatgtag attgaacaaa aagagcaggg tcaacattaa 21660 tgtcagaaat tagctgagaa gtaaactctt gcatgctatt aagagccttc cttttatcgt 21720 caacagccca caaaaacttt agatttgcat agacaattga agggtgagtc ttctttaaga 21780 cgagtgaatt atctaagttt tcgtcgtctt caaggagtaa attaagtgat tttttcgcta 21840 gactgatcct accagatttt ctgcagagat tagcgaattt gatccacatc tccatgttat 21900 cacggggtga aataactaaa gatcgtattc ttaacattct ttgccaaaca tccacatttc 21960 tctgacagcc tttcaaacgt ctaacccatg tcttctttat catttcacga acttcgggtt 22020 tgtcctcggc ttttttatag gtaatgattt cttctaattc ggataacatt tgaacacgga 22080 cagcaacgct gtaagcccta ttataacttt caccaacaag cgcagtaagc tcagtatcaa 22140 gtaaatctcg agctctggtg atataagaag ctgcttcttc aaattgtgat cgatgtagag 22200 ccacaatcgc gttaaaaaaa gctttatctg gtgactcaga cttcataaca gaaatatatt 22260 catccatttg ctcccattga cctaaccccc aagcagcggc tacggaaagc ggtgcaatat 22320 accgtcgcgc atcatgacca gcatgaatcc aattttcttg agctaactga gataatcgat 22380 cccattcacc caaagcgtgt aaacaacgaa gtttgcccat cgttatttcg aaattgccag 22440 cgccagcagc ttctcttttt tcataagctg acagagcatc ttcccacctt tgtaactttt 22500 cgtaccaagt ttctttaaga ttcattttgt catgctgctg agcatgttta agtattccaa 22560 tagctgcgtc tggttgttgg agttgattat tgattgaaat tagggcctca attgtatcaa 22620 ccgaaggttt tgtcaccaat tcttcttcaa tgaattctag ctccttgtaa tgtaaagcct 22680 tagcaaacgc atggcattta gctgcatagg cacccaaagt acgaatatca atcggaagtg 22740 gtttatcatc atgctccata aattccgcaa gattgagtaa aatctgaata atttcaggag 22800 atatgtgtgg cgacgttaaa gctatctcaa tcgacttaac taattcttct tgaaagtgat 22860 catataattc agaccaacaa gaaacaaaac tagcgttaaa taagtccctg gctaaaggtt 22920 gataggcagc agccaaagca gcacatgctc gtaaggcatg tgaaggtgat tctcttaaga 22980 gagctacgcc taatcgtcgg atccattctt gccagtcatc cttagtcgat cgttgagatg 23040 cttcccacgc atttctgagg atttcttgat ttacaggaag ctttttagag gttatatcag 23100 cagcggaagc taccacatct aatttaggct tatcgtattt ttcataaggg ttgagtttta 23160 taggaagagg ctgttcttgt aaaaattgtt caacaagtat cgagtaggtt tcatgagtaa 23220 cgccattcat cttaaggcac ttatcaatca ttggaatgaa aatagcaaaa tcaacattaa 23280 gttgatatat aagcgcacat acagtatcca tactcacgcg aatgagagag gcattgttgc 23340 acgaaagcat acgcataaca ggatgtataa ttcttgatgc atattccgag agattaataa 23400 ccattgaaag tcgtccaatt gtaatcatta tactttcttt tataccgatt gaaacatcat 23460 ttcgctcata cagtcgaagt attggatcca agagcatatg aaaataatca gctaatgtat 23520 caccgaagac gatgaatgcg tgcaatacct tttttgtact gactgagtcc actgatacat 23580 cagagtcaaa tatttgtagc atcattacta ataaagatgg taagtatggc ttgaactctc 23640 cctgcattgc tctagccagt gattcaatta gcgacaaaat tgtaaattgt aaattagaat 23700 gcgggttcca aaaatctttg ataagcttaa ataaatctgg taaaaaactt cgtatgtgct 23760 gacgaacaat aaggaccaaa atacttagtt gctgaaaata aaactccaat atgttcgtag 23820 gacacgttct cataactgcg ataaattctg gaataatttg ggaaagaaag ggggcacatc 23880 tgagacccat ggtcttgaat atatacatta cagcttgaat aacagcagta tggtgaatag 23940 ttaaggacgg gtcttttaat atactcatca aagcagtaat cacgactgtg gggtaatatt 24000 catcggatga tggaccaatg cccgacatca gcaaagaaat gtcaggagga atgtttttct 24060 gttctggaac tactttttct gttccctttt ctaaaacacg atgcctattg ggatctaaag 24120 caccaagtgt acctattagt ttaatagtct ctcgacgaat agtaatatct tgttcggttt 24180 tcgttatgcc aataagtata tcaagtaaag aagggaattc aatatacgga tcaattacat 24240 atccggtgct gcttgataaa ttacccaaag cctttaaagc cgctgctctc ctaataggag 24300 aactttggtc ctgcaaagcc tcaattatta gcggcattaa gtctttaata aaaggaacaa 24360 taacctcacc gctgatttgg catatttcac caagcgaatt aacaatacta gctgccacaa 24420 ttgaactaga atctttagct ttgggtaaaa gtatttgcag tattggttcc acatgtgact 24480 ctattaagcg aggagctgct gcaattaata aacacaataa cttggcattc tcttctttag 24540 ttctgataat tgtagaatag tccaatattg ttaaagtttt taacattatt ttccttaaat 24600 atggcatcac ataggcaggg ttatagacat ttagtcttcc aattatccgt aatgcagatt 24660 ctcgtacagc aaagttttca tcattaatag caataaaaag taaacgaatt ttatctgctt 24720 gggctaaatg cttgttaaag cgagaatcga gagaattaag aacagttagc cgaatatctg 24780 gaacagtatc gcaaatacca actgttagaa gcttttctag cacttcggca actacttgaa 24840 tcgcatgatc actagtctgc gataaaatag gatcacgagc aaatagttgg gagcaggtta 24900 tggaggcggt tttgcgtact tccgggtcat tgttttcaag gtatacaact acacaatcct 24960 tcacaaattc attaagaata taaccggaga agtcaaaatt tcccaaaact tttagagcca 25020 aaatatagac gtcattggga aaaaatcctg tcttcaggga agcactcttt gaagatttta 25080 aagatcttgc tacatattgg ggaggacatc ctggaggaat aaaaggacga ccacttagaa 25140 ttttgctgag catatctaat agtcgttcct gtatgactgg taataatgga ggtatattat 25200 gggccagatc tgagagagca cggtaagaag cctcagaaag tccgcttgca aatattaagt 25260 caaagaggtc atacgcatag tttgaaaagg cttgtcctag tgctatagaa a 25311 //