ID SPBC1A45P standard; DNA; FUN; 26184 BP. XX AC AL031174; XX SV AL031174.1 XX DT 03-AUG-1998 (Rel. 56, Created) DT 13-NOV-2002 (Rel. 73, Last updated, Version 3) XX DE S.pombe chromosome II cosmid c1A4 left hand region 1-26184 bp Originates DE from chimeric cosmid. XX KW 3-isopropylmalate dehydrogenase; anaphase promoting complex component; KW beta-transducin; chaperonin; dna topoisomerase ii; KW t-complex protein 1 gamma subunit homolog. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-26184 RA Wood V., Rajandream M.A., Barrell B.G., Volckaert G.; RT ; RL Submitted (31-JUL-1998) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and Katholieke Universiteit Leuven, Laboratory of RL Gene Technology, Kardinaal Mercierlaan, 92 blok F, B-3001 Leuven, Belgium. XX DR GOA; O42971; O42971. DR GOA; O74341; O74341. DR GOA; O74343; O74343. DR GOA; P08096; P08096. DR GOA; P18869; P18869. DR GOA; Q9P7Y4; Q9P7Y4. DR SPTREMBL; O74337; O74337. DR SPTREMBL; O74338; O74338. DR SPTREMBL; O74339; O74339. DR SPTREMBL; O74340; O74340. DR SPTREMBL; O74342; O74342. DR SWISS-PROT; O42971; AN10_SCHPO. DR SWISS-PROT; O74341; TCPG_SCHPO. DR SWISS-PROT; O74343; YH2X_SCHPO. DR SWISS-PROT; P08096; TOP2_SCHPO. DR SWISS-PROT; P18869; LEU3_SCHPO. DR SWISS-PROT; Q9P7Y4; PMC1_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c1A4 is overlapped at the 5' end by cosmid SPBC1E8, CC EM:AL021746 and at the 3' end by p1 clone SPBP23A10, EM:AL136535. XX FH Key Location/Qualifiers FH FT source 1..26184 FT /chromosome="II" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c1A4" FT /map="IIR" FT misc_feature 1..3026 FT /note="nominal overlap with cosmid SPBC1E8, EM:AL021746 S. FT pombe chromosome 2" FT CDS join(1241..1407,1479..1805,1864..1939) FT /db_xref="GOA:O42971" FT /db_xref="SWISS-PROT:O42971" FT /gene="SPBC1A4.01" FT /gene="SPBC1E8.06" FT /gene="apc10" FT /protein_id="CAA20105.1" FT /translation="MAQIRQEALKKQKSETQKSTEGFVDIGNLAQWTCSSEKSGFPIRL FT VRDDNIDTYWQSDGSQPHTIHIKFVKRVSIKYVSMYLQYTLDESYTPSTLRISAGTGFQ FT DLEIVTTVQVEEPTGWVHVPVGDFGRNGLLDVHLIQIKILANHQSGKDSHVRLIKIYAP FT EIEQPAIAVDEIPYTSLQFISRNQLR" FT misc_feature 1408..1413 FT /note="gtaagt, splice donor sequence" FT misc_feature 1452..1478 FT /note="ctaactataattttctttgtctttaag, splice branch and accep FT tor" FT misc_feature 1806..1811 FT /note="gtacgt, splice donor sequence" FT misc_feature 1849..1863 FT /note="ctaacactgatgcag, splice branch and acceptor" FT CDS complement(2362..3477) FT /db_xref="GOA:P18869" FT /db_xref="SWISS-PROT:P18869" FT /gene="leu1" FT /gene="SPBC1A4.02c" FT /gene="SPBC1E8.07c" FT /EC_number="1.1.1.85" FT /protein_id="CAA20106.1" FT /translation="MCAKKIVVLPGDHIGPEIVASALEVLKVVEKKRPELKLEFEEHKI FT GGASIDAYGTPLTDETVKACLEADGVLLGAVGGPEWTNPNCRPEQGLLKLRKSMGVWAN FT LRPCNFASKSLVKYSPLKPEIVEGVDFCVVRELTGGCYFGERTEDNGSGYAMDTWPYSL FT EEVSRIARLAAWLAETSNPPAPVTLLDKANVLATSRLWRKTVAKIFKEEYPHLTLKNQL FT IDSAAMLLVKSPRTLNGVVLTDNLFGDIISDEASVIPGSLGLLPSASLSGVVGKSEEKV FT HCLVEPIHGSAPDIAGKGIVNPVGTILSASLLLRYGLNAPKEAEAIEAAVRKVLDDTSI FT GGRGLYTRDLGGEASTADITKAVVEELEKIL" FT misc_feature complement(2377..3471) FT /note="Pfam match to entry isodh PF00180, Isocitrate and is FT opropylmalate dehydrogenases" FT 3'UTR complement(4035..4126) FT /note="mRNA from AU011723" FT CDS join(complement(8557..8640),complement(4127..8500)) FT /db_xref="GOA:P08096" FT /db_xref="SWISS-PROT:P08096" FT /note="anomoly: predict additional N-terminal exon which FT increases homology with TOP2_CANAL/P87078" FT /gene="SPBC1A4.03c" FT /gene="top2" FT /EC_number="5.99.1.3" FT /product="DNA topoisomerase II; DNA gyrase B domain; FT similar to S. cerevisiae TOP2" FT /protein_id="CAA20107.1" FT /translation="MSIDADFSDYEDEASGDENVLPNTTTKRKASTTSSKSRAKKASTP FT DLRQTSLTSMTASEQIPLVTNNGNGNSNVSTQYQRLTPREHVLRRPDTYIGSIEPTTSE FT MWVFDSEKNKLDYKAVTYVPGLYKIFDEIIVNAADNKVRDPNMNTLKVTLDPEANVISI FT YNNGKGIPIEIHDKEKIYIPELIFGNLLTSSNYDDNQKKVTGGRNGYGAKLCNIFSTEF FT VVETADKERMKKYKQTWYDNMSRKSEPVITSLKKPDEYTKITFKPDLAKFGMDKIDDDM FT VSIIKRRIYDMAGTVRETKVYLNNERISISGFKKYVEMYLASDTKPDEEPPRVIYEHVN FT DRWDVAFAVSDGQFKQVSFVNNISTIRGGTHVNYVANKIVDAIDEVVKKENKKAPVKAF FT QIKNYVQVFVNCQIENPSFDSQTKETLTTKVSAFGSQCTLSDKFLKAIKKSSVVEEVLK FT FATAKADQQLSKGDGGLRSRITGLTKLEDANKAGTKESHKCVLILTEGDSAKSLAVSGL FT SVVGRDYYGVFPLRGKLLNVREASHSQILNNKEIQAIKKIMGFTHKKTYTDVKGLRYGH FT LMIMTDQDHDGSHIKGLIINYLESSYPSLLQIPGFLIQFITPIIKCTRGNQVQAFYTLP FT EYEYWKEANNNGRGWKIKYYKGLGTSDHDDMKSYFSDLDRHMKYFHAMQEKDAELIEMA FT FAKKKADVRKEWLRTYRPGIYMDYTQPQIPIDDFINRELIQFSMADNIRSIPSVVDGLK FT PGQRKVVYYCFKRNLVHETKVSRLAGYVASETAYHHGEVSMEQTIVNLAQNFVGSNNIN FT LLMPNGQFGTRSEGGKNASASRYLNTALSPLARVLFNSNDDQLLNYQNDEGQWIEPEYY FT VPILPMVLVNGAEGIGTGWSTFIPNYNPKDITANLRHMLNGEPLEIMTPWYRGFRGSIT FT KVAPDRYKISGIINQIGENKVEITELPIRFWTQDMKEYLEAGLVGTEKIRKFIVDYESH FT HGEGNVHFNVTLTEAGMKEALNESLEVKFKLSRTQATSNMIAFDASGRIKKYDSVEDIL FT TEFYEVRLRTYQRRKEHMVNELEKRFDRFSNQARFIHMIIEGELVVSKKKKKDLIVELK FT EKKFQPISKPKKGHLVDLEVENALAEEEQSGDVSQDEDSDAYNYLLSMPLWSLTYERYV FT ELLKKKDEVMAELDALIKKTPKELWLHDLDAFEHAWNKVMDDIQREMLEEEQSSRDFVN FT RTKKKPRGKSTGTRKPRAIAGSSSSTAVKKEASSESKPSTTNRKQQTLLEFAASKEPEK FT SSDINIVKTEDNSHGLSVEENRISKSPGLDSSDSGKSRKRSQSVDSEDAGSKKPVKKIA FT ASASGRGRKTNKPVATTIFSSDDEDDLLPSSLKPSTITSTKASAKNKGKKASSVKKQSP FT EDDDDDFIIPGSSSTPKASSTNAEPPEDSDSPIRKRPTRRAAATVKTPIYVDPSFDSMD FT EPSMQDDSFIVDNDEDVDDYDESD" FT misc_feature complement(6665..8353) FT /note="Match to PF00204 DNA_topoisoII, DNA topoisomerase II FT (N-terminal region) Score 1148.41" FT misc_feature complement(8501..8516) FT /note="ctaacaacaacttttttag, splice branch and acceptor" FT misc_feature complement(8551..8556) FT /note="gtatgc, splice donor sequence" FT CDS 11147..11896 FT /db_xref="SPTREMBL:O74337" FT /gene="SPBC1A4.04" FT /product="hypothetical protein; sequence orphan" FT /protein_id="CAA20108.1" FT /translation="MESCTRSSLQQLVAADSKSSNFCFRNLSQSSNNNVSYASSSNRNF FT VPQNVLNNEYQSFQHSSTSQPSVLRQGKNAFLKPSQLSFNMNSSEISNTHWARDFNILT FT SNFASSSVTSAPTQSSHISNFTNSQKYFANDLPNSLTDQPLAQPSASQRSTWLPCSAAV FT STSSPSSDPFFDSYLEQAFEKAERLANEQQKISKVEKTFGTLDSIGTEQDDCFDPDYSN FT LPLFPQENASPPLFRKASCNSGFTTKC" FT CDS join(12390..12436,12490..14545) FT /db_xref="SPTREMBL:O74338" FT /gene="SPBC1A4.05" FT /product="hypothetical protein; sequence orphan; predicted FT coiled-coil protein" FT /protein_id="CAA20109.1" FT /translation="MSKSAFTSKSQLKGIDGSFNDPFRQPSMNLPTPPHDDGLPSIPRS FT TALPNLSNRLSPYSHRNYLPIPEADSRNLEVLNSISLTTGSVVNQINKLYQRSCDNANY FT LQDLRSLILQTPTAEANATQVTESLNQIQKILQEASSKDREQIVQVIKELNKGNSLEVR FT RELGNCLAHLKKGTLNIDNALQASLQKYWKELQYFNVSKDKLLSLEESIKLLSARLEET FT DTPSSTHWIEINAGFKEVGDELSENFQRKQEILSGLQNNVILRTNNRKPVGSDGSNSNF FT NGGEEQMDSKDQEEIQDYLNSLLSVHEKDGVLLQKFHNSYVQYQKLAVALSKYENFDAD FT KLFQQMNLAKQSNETLLQTLTEQTDQLLSFKETMDSFKFILGPSMENQALQQGILAEQQ FT DLVAQLRDIVLRSETLAENPSNMPGSCLPGASSNTADEFTEQLNLLKNEVARLSAICPS FT PNSGINASVLTNADNLEKENLLLVNNNAFKVDDRSVSSVALDDHNRQLQMNVEELEGKK FT ADLTSKINRLDKDFVKLNTTYSLLTDQVKTKQLALQEIESRVIRLEERLNMLQKLSMQP FT AISSSSEFVPIESHPSSSAVVPIEEPKNSIIEKKRVPHNAARNSVNLEVTLPNSKKRFS FT SFSGSSSKLPVRPSTALTDKRKPSWSRRLAAAIGFSSGSPEKKHVITSSDAGHQRSKSR FT SFSSKM" FT misc_feature 12437..12442 FT /note="gtatgt, splice donor sequence" FT misc_feature 12473..12489 FT /note="ctaacggtaattaatag, splice branch and acceptor" FT CDS join(complement(15955..16227),complement(15611..15889), FT complement(14950..15549)) FT /db_xref="SPTREMBL:O74339" FT /gene="SPBC1A4.06c" FT /product="conserved eukaryotic protein; similar to proline FT transport helper protein; similar to S. cerevisiae YGR046W" FT /protein_id="CAA20110.1" FT /translation="MIFGKTHFLSYNILRYSTKRWMNRHSYSHHAKCTVAQLLKQNLLT FT FENQRIQPEEELKENLTKVVNYFQAPIDVAVGYGSGVFRQAGYSQKENPMIDFIFQVED FT PVKWHKINLQQNPSHYSFVKNFGPGFVSTLQESFGTGVYYNTHVEVEGNIIKYGVTSKK FT DVYEDLKNWNTMYLAGRFQKPVVILKGEDEFYKENSYNLSSALHVGLLMLADRFTEFDL FT YKTIVSLSYLGDIRMSFFAENPRKVENIVSKQIAFFRKLYLPLLYAEPGVHFIESSEVL FT KSMDPSDNSRYLSFHQNITKDSISRLLNGLPLNLVKILGLKPDTSSFEKCAELMLTNQI FT STRSLLISKSIKKLTSFSILTQSIKGIFTARCHSFRWYMSMRS" FT misc_feature complement(15550..15571) FT /note="ttaaccgaatttgaacaaatag, splice branch and acceptor" FT misc_feature complement(15605..15610) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(15890..15909) FT /note="ctaacttatgtctctgctag, splice branch and acceptor" FT misc_feature complement(15949..15954) FT /note="gtaaat, splice donor sequence" FT CDS join(complement(17965..18226),complement(16860..17908)) FT /db_xref="SPTREMBL:O74340" FT /gene="SPBC1A4.07c" FT /product="WD repeat protein; putative U3 snoRNP complex FT associated; putative ribonucleoprotein (RNP) complex (PMID FT 12068309); putative small subunit (SSU) processome FT component (PMID 12068309); possibly involved in rRNA FT processing (PMID 12068309); localization nucleolar (PMID FT 12068309); similar to S. cerevisiae SOF1" FT /protein_id="CAA20111.1" FT /translation="MKVKTITRGTSLTRLNDQDPVKRNLDPSLHPFERAREYTRALNAT FT KMDRMFAAPFLGQLGRGHQDGVYSLARDTKTLIDCASGSGDGAVKLWDASERCERWTSK FT AHEGIVRGLVFSNQGDVLSCASDRYVYMLNKQDGKVKRSYLGDSSLLDIDTSKGGDLFA FT TSGENVSIWDYSRDTPVTKFEWGADTLPVVKFNYTETSVLASAGMDRSIVIYDLRTSSP FT LTKLITKLRTNSISWNPMEAFNFVAGSEDHNLYMYDMRNLKRALHVYKDHVSAVMSVDF FT SPTGQEFVSGSYDKTIRIYNVREGHSRDVYHTKRMQRVTAVKFSMDAQYIFSGSDDSNV FT RLWRARASSRASIRSTREENRLKYLDSLRERYKHIPEIRRIARHRHLPTNVKKAAEIKR FT EEINSLKRREENIRRHSKKGAVPYEKERERHVVGIQK" FT misc_feature complement(17142..17222) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 31.40" FT misc_feature complement(17268..17375) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 39.61" FT misc_feature complement(17579..17698) FT /note="Pfam match to entry PF00400 WD40, WD domain, G-beta FT repeat, score 5.00, E-value 12" FT misc_feature complement(17708..17818) FT /note="Pfam match to entry PF00400 WD40, WD domain, G-beta FT repeat, score 6.40, E-value 7.9" FT misc_feature complement(17825..17938) FT /note="Pfam match to entry PF00400 WD40, WD domain, G-beta FT repeat, score 10.60, E-value 2.3" FT misc_feature complement(17909..17924) FT /note="ctaacacattttctag, splice branch and acceptor" FT misc_feature complement(17948..18067) FT /note="Pfam match to entry PF00400 WD40, WD domain, G-beta FT repeat, score 18.40, E-value 0.17" FT misc_feature complement(17959..17964) FT /note="gtatgt, splice donor sequence" FT CDS join(complement(20313..20337),complement(20201..20274), FT complement(18643..20130)) FT /db_xref="GOA:O74341" FT /db_xref="SWISS-PROT:O74341" FT /gene="SPBC1A4.08c" FT /gene="cct3" FT /product="t-complex protein 1, gamma subunit; similar to S. FT cerevisiae CCT3" FT /protein_id="CAA20112.1" FT /translation="MQSPVFVMNTNGNRQVGHKAQMSNIQAAKAVADVIRTCLGPRAML FT KMLLDPVGSVLLTNDGHAILREIEVAHPAAKSMIELARTQDEEVGDGTTSVIILAGEIL FT AAASPLLDRKIHPVVMIRSFKQALEDALSIIDEITLPVNVDDNAEMFRLIRTCIGTKLV FT ARWSDLMCHLALRAVRTVASTSNGRMEIDIKRYARVEKVPGGEIESSCVLDGVMLNKDV FT THPKMRRRIENPRIVLLDCPLEYRKGESQTNIEISKDTDWNRILEIEEEQVKRMCDYII FT AVKPDLVITEKGVSDLAQHYLLKANITALRRTRKSDNNRIARACGANIVNRLEDLREKD FT VGTGCGLFYIDKLGDEYYTFLTGCKNPKACTILLRGPSKDIINEVERNLQDAMAVARNV FT FFHPKLSPGGGATEMAVSVRLAEKARSIEGVAQWPYRAVADAIEIIPRTLVQNCGANPI FT KALTELRAKHAEGQHSFGIDGETGRVVDMHEYGVWEPEAVKLQSIKTAIESACLLLRVD FT DIVSGVRKHSE" FT misc_feature complement(18658..20130) FT /note="Match to PF00118 cpn60_TCP1, TCP-1/cpn60 chaperonin FT family Score 593.58" FT misc_feature complement(20131..20142) FT /note="ctgacattatag, splice branch and acceptor" FT intron complement(20131..20200) FT /note="confirmed intron" FT misc_feature complement(20195..20200) FT /note="gtacgg, splice donor sequence" FT misc_feature complement(20275..20288) FT /note="ttaattaaccaaag, splice branch and acceptor" FT misc_feature complement(20307..20312) FT /note="gtaagt, splice donor sequence" FT CDS complement(21150..21524) FT /db_xref="SPTREMBL:O74342" FT /gene="SPBC1A4.11c" FT /product="very hypothetical protein" FT /protein_id="CAA20113.1" FT /translation="MPEKDWIGEFGPSKFKSPIDKLNQLLPESNDPSILYETSQHLLSE FT FDKTLNDSLRVLNQQINQVSEVLPRLPTMISALDRESKRLFESCEKMDPEPSALMPLQE FT LEKIRSNIQLTISQIDNLTP" FT CDS 21801..23843 FT /db_xref="GOA:O74343" FT /db_xref="SWISS-PROT:O74343" FT /gene="SPBC1A4.09" FT /product="conserved protein; similar to S. cerevisiae FT YOR243C; UPF0024" FT /protein_id="CAA20114.1" FT /translation="MSQENHVDVPRKRIRIDQSESSRNLERNGLEDEANAPSDLSGQKF FT YMTESDVGIDAFLNPNLPSIDGIIKARFTDFAVFEVDTDGNIVHLTDMEAHDPILSKAT FT GDKETEDAKDSSNQDISNDQKAPSFKEQEPATLPILPNDLQSIIPKGIGNEFIQSLHKL FT SVGEITDPISLILPENTPPMDKGQRTILHQFIRNNFSGLESSTKGNGTFTVSKTTRKNQ FT PRSRRDPRLSWKALGGEYCHFHLYKENRDSMDCLGKIARLLKVPTRTLSIAGTKDRRGV FT TCQRVAIHHVRASRLAQLNSGSLKNSTYGFLLGNYSYKNSNLRLGDLKGNEFHIVVRNV FT ITPKEKVVEALNSLKEHGFINYFGLQRFGTSSVGTHTIGVRLLQSDWKGAVDLILSPRP FT EHTGSVKEAIDLWHSTHDAEASLRILPRRMIAESSILETWSRSGNQTDYLGAFQRIPRH FT LRSIYPHAYQSYVWNRVASWRIKNLGDRPVVGDLVYSTESNGLSQKSPIVDPEAPDLLE FT DLPVSSKLSARPIEEDEVNNFSIYDIVLPLPGRNVIYPKNETFDIYKSVMNEASLDPLN FT MSRKDRELSLPGDYRKLLVRPENMEFNFIKYDNMEQQLILTDKDRLENRSISVSSEVGK FT HTAVTLKFVLPSSAYATMALREALRTATASGDQRMLMPAVLKDSI" FT misc_feature 22350..23624 FT /note="Match to PF01142 UPF0024, Uncharacterized protein FT family UPF0024 Score 194.26" FT CDS complement(24163..>26184) FT /codon_start=1 FT /db_xref="GOA:Q9P7Y4" FT /db_xref="SWISS-PROT:Q9P7Y4" FT /gene="SPBC1A4.10c" FT /gene="SPBP23A10.01c" FT /gene="pmc1" FT /product="mediator complex component; RNA polymerase II FT holoenzyme complex; involved in regulating RNA polymerase FT II activity; similar to S. cerevisiae RGR1 and YLR071c" FT /protein_id="CAA20115.1" FT /translation="DPKSTGISFQWIVVDFQFHLPDFSSTPAKYRVFIELHLNEEIAAA FT FVLQKPILPLIYNILHKFCLYQRLNLLSQQTFQLSRESWLGHLRGVYDEKPPRLRLYYW FT PQLNVKKEGKPGKIGHYIHIFVNTQPISAFERTLSSKRSSCEYDHFLLLVEWHHDGIVE FT HVPLDDHMDAQHLLLLITQKHAQLILEQIRKELHPNIFSEHVGGGLKIHVFDNEIIVKV FT NSVTGRLVLSSSASPLSPPRHLRAAEKNIALNTQPPAQILNRLYFFCIQTQLLEVAQCA FT ELHAVQGYYSFPYLTFSKGKWRKDGDSLWVLAYNVESNSWSVRLLNAAGQTLYTQDVHT FT TKGTLSIESFSRLSYLLEVQILLFNVQTACQARGMPFEYLPIPPKALIEDDFTTYVQTG FT CLCIMMPSSNEDMLPVVFVRAHDGQLIFDSRIKGKLPYQSETETEKNCYIDWRTGRITI FT RVQNFSSFEKTWIGLLKLVALSKTSAFNVDCITLKHVDFTYLDDEKFRATIHDDNTFTL FT HFFNRHSPFHLISQFLQDTFSDGPSAIQPLRVIMDRTRGVLVAQELGYVVLARSLRQYR FT IILSKNHGIQVLLNRHGCILQDLSYLSADSRYLEGTQTLTSQWEPCSWLNTVWEGDLGD FT DELNGQIEAAPEMHLIKMNKTADLTAILKRILAISRKK" FT misc_feature 25584..26184 FT /note="nominal overlap with p1 clone p23A10 S. pombe FT chromosome 2" XX SQ Sequence 26184 BP; 8381 A; 4980 C; 4660 G; 8163 T; 0 other; gatcatcatt gctttgccag tgtgttgtgt ttattgtttg taaatctcta aaactctttt 60 cgatgatggt atttctccaa tggtgtactg atgatggtaa aatttaacat ttatgtgaca 120 tggttctctt ctgtaaatgt tttgcagcgt actattgttt tatcatttgg aaagtatggt 180 gtgcttgcat gaagtctgga ggttgtacaa atctttttgt tttgggggca tctggatgtt 240 tgtcgcactc gtattttgta cggtgacaat ttcgataagt cttttatcat ctgtgcccga 300 tatgttggaa atgttgaata attggatatc aatgtgcaat tacagtataa ggaagacttt 360 gaattctgtt tgtctataaa gttgcgtttg actgcaaaac attgaatatt tacagtcggt 420 ttactttgta tacaaaaatg tgtaatcctt ttactttacg aatttacgtt cgcttgtctt 480 actgaatcta tctatagctt ggaccacgac gggtgctttg aagggttggc tgctaataat 540 tcttctttga tctaatccag tataacttcc tatttcggca ttcaaaaagt ctatagagtt 600 ctgtaatatc gcgaattggt tcatcttggc aagacaaatt gctcattact ttgtaaatca 660 atataattca aacactgtgt ctttcataaa atgacttttt tgcattcgca taagtgtatt 720 gatctatctt tctttctttt ttagctttat aataaaacaa tgaatactgc atgatataag 780 cgttacacaa ttctttttcc ctactgctgc aataagtctt ttaaagaagt tggatttaag 840 ccaacaatag acaggtatat ctgtgtatgt tgagtcaata aaaactaaaa agcctgttta 900 tctgtagtac tataacttac attgtttttc tggtttgaat atatattaac gaactattct 960 attagtaatg tatgctcaca acgagtacac gtcgctcttt acgttccata aaaggtactt 1020 gattcttcag ctaaccagcg ctagactttt ttattagtat atcagaggag tgaatttttg 1080 aaacttgtgc actcgacatt attctctaac aacactttat tataattatt gagaaccgtt 1140 taatggttgt atagcgtaca catttgtaaa tatagataag gaagccttgg gaggacgtta 1200 tgtcaacatc tcacaagtcc gcattgttta catttagctt atggcgcaaa ttcgacaaga 1260 agcattgaaa aaacaaaagt ctgagacgca aaaatcaaca gaagggttcg ttgatattgg 1320 aaatttggct caatggacct gctcgagcga aaaatccgga tttcctatac gcttggtgcg 1380 ggatgataat atcgatacat attggcagta agtgtatttg tataaatata gtcagggaag 1440 aaaatgtttt actaactata attttctttg tctttaaggt ctgacggctc tcaacctcat 1500 accatccata ttaaatttgt aaagcgagta tcgattaagt atgtgagtat gtaccttcaa 1560 tacacccttg atgaatctta tactcccagt actttgcgaa tatcagctgg gacagggttt 1620 caagatttgg aaattgttac aacagttcaa gtcgaggaac caactggttg ggtacatgtg 1680 ccagttggtg attttgggcg aaatggcttg ttagatgtgc atttaataca aatcaaaata 1740 cttgcgaacc atcaaagtgg aaaggatagt catgttcgtt tgataaaaat atatgcgcca 1800 gaaatgtacg tattttgcat agcaaaatct tcattaatat aaaatgtgct aacactgatg 1860 cagagagcag cccgcgatag ctgtggatga aattccctac acaagtttac aattcataag 1920 tagaaaccaa ttacggtaat gcaaaagtca tgtctctggc tctctcaaag aatcgggttg 1980 tcatcgttac aataataatt gttacgttct cgaattttta tggttttttt cttcttttcc 2040 cctattattt atgttacagg ttacttcgtt taaaaagaaa taattaatga tattatgttt 2100 gaaacttttc atagtaaaaa aagagtaagt acacagcgac aactcggtca taaagttgaa 2160 cggatgtcgt aaatcaattc catgcttttg caacttaata catctttgct tgactataac 2220 ataccaaaag aaaaaacatt agagccttaa aatttacgct tttgtcaatt gcatttttaa 2280 cgataataaa tatgcgacac aattaatcaa taaaaattag gtcaaatcaa atcatatgaa 2340 tttattctac attaaaccct attacaaaat tttttcaagt tcttcaacaa cagccttagt 2400 aatatcagcg gtagaagcct cacctcccaa atcgcgagta taaagaccac gtccaccaat 2460 tgaagtatca tccaagacct tgcgtacggc ggcttcgata gcttcagcct ccttaggagc 2520 attcaaacca taacgaagga gaagggaagc agataaaatt gtaccaacag gattaacaat 2580 gcccttgcca gcgatatcgg gagcgctacc gtgaatgggc tcaaccaaac aatgaacctt 2640 ttcttctgat tttcctacca caccggaaag ggaggcagaa ggcaaaaggc ccaagctacc 2700 aggaatgaca gaagcctcat ctgaaataat gtcaccaaac aagttgtcag tcaaaacaac 2760 accgttaagt gtacgagggc tcttgaccaa aagcatggct gcggagtcaa tgagctggtt 2820 ttttaaggta aggtgaggat attcctcctt aaaaatctta gctacagtct tgcgccaaag 2880 acgagaagtt gccaaaacat tagctttgtc gagtaatgtg acgggagcag gagggttgga 2940 agtttcagct aaccaagcag ccaaacgagc aatacgagaa acttcttcca aactgtaagg 3000 ccaagtgtcc atagcataac ccgatccgtt gtcctcagtg cgctcaccaa agtaacaacc 3060 tccagtaagt tctcgtacaa cacaaaaatc gacaccttca acgatttcag gcttcaaagg 3120 gctgtacttg actaaagact tgctggcaaa gttgcaaggt cgaaggttgg cccaaacacc 3180 catactctta cgaagcttca ataaaccttg ctcaggacga caattggggt tggtccattc 3240 aggaccacca acggcaccca aaagaacacc gtcagcttcc aaacaagcct tcacagtctc 3300 gtcagtcaaa ggggttccat aggcatcaat agaggcacct ccaatcttgt gttcttcaaa 3360 ctcgagtttt aactcaggtc gcttcttctc aacgactttc aaaacctcca aggcagaagc 3420 aacaatttca gggccaatat ggtctcctgg taagacgacg attttctttg cacacatgtt 3480 gttgaagaag ttttgttgtg aaatggtttc gtgaaagttt cagaccctac cgcaaaaatg 3540 cctggtttcg ggaaactcaa cactgttgca ctttttatac tacagattgg gatatcgata 3600 atattgcgta aaaaatcctt tttttaaaaa gcttgtttac agtaacgtaa atgaccagaa 3660 atcagatgaa aatcacaaga aagcaaataa ttcacgttaa atcctgatat gtttgatttt 3720 gtgatgaaat catggatgtt cataggaatt gttgaaattg cgctttttta acgaaatata 3780 caagtatcct ggagcttact taattaatta atgaatcttt gtttctagat attaaaatag 3840 tagcctcaat tatcagcgct ttctacgtta gtaaacgaaa tttttaatgt caaaaaaatg 3900 tttaatagac agtacgaata tgcattataa tgttcataaa taatttgagt atgtgtacga 3960 gttgtcttta aacccacaga ggtagaatgt atatataaaa ttaataagct aagtgtaata 4020 cttaaaaaat acattaattg gaactcgtat cctaccattt acaatgttca tccaattttt 4080 tcagattgta ctgtaaatag cgtttgaaaa caccaaattt tagaagctaa tcactctcat 4140 cataatcgtc tacatcctca tcgttatcga cgataaaaga atcatcttgc atgctgggtt 4200 catccatgct atcaaacgag ggatcaacgt aaataggtgt tttcactgta gccgctgctc 4260 ttctggttgg cctctttcta atcggagaat ctgaatcttc tggtggctct gcgttagtcg 4320 aactagcttt tggagttgaa ctactacctg gaataataaa atcatcatcg tcatcttcag 4380 gtgattgttt ctttaccgag cttgcttttt tccctttatt cttcgcagaa gccttcgtgg 4440 atgttatggt ggaaggtttc aaactgctag gcaacaaatc atcttcatcg tctgaagaaa 4500 atatggtagt agcaactggt ttattagtct ttcttcctct tccagacgcc gaggctgcta 4560 tttttttgac gggtttttta ctacctgcgt cttcagagtc aacagattga cttctttttc 4620 ttgattttcc actatcactg ctatccaatc ccgggctctt agatatgcga ttttcttcaa 4680 ctgataagcc atgagagtta tcctctgtct tgacaatgtt tatgtcagat gatttctcag 4740 gttctttcga cgctgcgaac tcaagtaaag tttgttgctt tcgatttgtt gtagatggtt 4800 tggattcgct gctagcttct tttttaacag cagtacttga ggaggatccg gcaatagccc 4860 tgggtttcct agtaccagtg gatttacctc gaggcttctt tttcgttcga tttacaaaat 4920 ctctagagga ttgctcttct tctaacattt ctctctgaat atcatccata accttattcc 4980 aagcatgctc aaatgcatcc aaatcatgaa gccacaattc tttaggagtt tttttaatca 5040 aagcatccag ttcggccatt acttcgtcct ttttcttgag aagttccaca taccgttcat 5100 aggtcaaaga ccataaaggc attgaaagaa ggtaattgta ggcatctgaa tcctcgtctt 5160 gcgaaacatc accagattgt tcttcttcag caagagcatt ttcaacttct aaatcaacca 5220 aatgcccttt ctttggttta ctgataggtt gaaacttctt ttccttcagc tccacaatga 5280 gatccttttt cttctttttt gaaactacaa gctccccctc tataatcata tgaataaacc 5340 gcgcttgatt tgaaaatcta tcaaaccttt tttccaattc attaaccata tgctctttac 5400 gtctctggta tgtccttaaa cgtacttcgt aaaactcggt caaaatatct tcaacactgt 5460 catacttctt gatccgtcca gatgcatcaa aagcaatcat attactcgtt gcttgagtac 5520 gcgacagttt aaacttaact tccaaggatt catttaatgc ttctttcatg ccagcttcgg 5580 taagcgtgac attaaagtga acatttcctt caccgtgatg gctttcatag tccacgatga 5640 atttacgaat tttttccgta ccaacaagac cagcctccag atactccttc atatcctgag 5700 tccaaaatcg tataggcaat tcagtaattt ctactttgtt ttcaccaatt tggttaatta 5760 taccagatat tttgtacctg tcaggcgcaa ctttcgttat acttccacga aagccgcggt 5820 accagggagt cataatttcc aaaggctcgc cattaagcat atgtcttaaa ttagcagtta 5880 tatccttagg gttataatta ggaataaaag tagaccagcc agtaccaata ccttcggctc 5940 cattgacaag taccatggga agaattggca cataatactc tggttcaatc cactggcctt 6000 cgtcgttttg gtaattaaga agctggtcat cattggaatt aaataaaaca cgtgctaagg 6060 gtgataaagc tgtatttaga taccttgaag ccgatgcatt ttttccaccc tcagatcgtg 6120 taccgaattg tccattaggc atcagcaaat taatgttgtt actgccaaca aaattttggg 6180 caagattaac tatagtttgc tccatcgaaa cctcgccatg gtggtatgca gtttcactag 6240 caacatagcc ggcaagtcta ctgactttag tttcatggac gagattgcgt ttaaaacaat 6300 aatagacaac tttacgctga ccaggcttca agccatctac tactgaagga atcgaacgga 6360 tattatcagc catactgaat tggataagct ctcgattaat gaagtcatca atcggaatct 6420 gaggttgagt ataatccata tatataccag gtcgatacgt tctaagccat tccttacgca 6480 catcggcctt tttcttggca aatgccattt caattaattc agcatccttc tcctgcatgg 6540 catgaaagta cttcatgtga cgatcaaggt ctgaaaaata acttttcata tcgtcatggt 6600 cacttgttcc caaacccttg tagtatttaa ttttccaacc acgtccattg ttattagctt 6660 ccttccagta ttcgtactcg ggtaaagtgt aaaatgcttg aacctgattg ccacgagtgc 6720 acttaatgat aggtgtgata aattggatca agaatccagg aatttgcaaa agagaaggat 6780 acgaggattc taaataatta ataattaaac ctttaatatg tgatccatca tgatcttgat 6840 ctgtcataat cattaaatga ccataacgaa gacctttcac atcggtataa gtttttttat 6900 gagtgaatcc catgattttc ttgatagctt gaatttcttt gttatttagg atttgggaat 6960 gagaagcctc ccgtacattc agtagttttc ctcttaacgg aaaaactcca taatagtctc 7020 taccaacaac actgagaccc gaaacagcta aagatttagc agaatctccc tcagtgagga 7080 taaggacaca cttatgggat tctttggtac ccgctttatt tgcgtcttcg agtttggtta 7140 aacccgttat acgagaacgc aaacccccat cgcccttact gagttgctga tctgccttag 7200 cggtagcaaa ttttaaaacc tcctccacta cagaagattt tttgatagct tttaaaaatt 7260 tatcacttaa tgtgcattga gagccaaaag cagaaacttt cgtggtgaga gtctcctttg 7320 tttgggaatc aaaggatggg ttctctattt gacaattgac aaatacctgt acgtaatttt 7380 ttatttgaaa cgctttaacg ggtgcctttt tattctcctt cttgacgact tcatctatag 7440 catcgacaat tttattggca acataattaa catgtgtacc tccacgaatg gtagaaatat 7500 tgttaacaaa cgaaacctgc ttaaactgtc catctgaaac agcaaaggcc acgtcccaac 7560 ggtcattaac atgttcataa attaccctag gaggctcttc atcaggttta gtgtcagaag 7620 caagatacat ctccacatat ttcttaaatc cacttatact gatgcgttca ttgttcaggt 7680 aaactttagt ttcacgaacg gtacctgcca tatcataaat acggcgtttt ataatagata 7740 ccatatcatc atcaatcttg tccataccaa attttgctaa atcgggtttg aatgtaattt 7800 ttgtgtattc atcgggtttc ttgagagaag tgatcactgg ctcagacttt ctggacatat 7860 tgtcatacca agtttgttta tatttcttca tcctttcctt atcagctgtc tcaacgacaa 7920 attcagtaga aaaaatattg caaagttttg cgccgtaacc atttcttcct cctgttacct 7980 tcttttgatt atcgtcgtaa ttgcttgaag taagcaagtt accaaaaata agctcgggga 8040 tgtaaatttt ctctttatca tgaatctcta taggaatgcc cttgccattg ttataaattg 8100 atatgacatt tgcttcagga tccaaagtca cctttagggt attcatgttt gggtcgcgaa 8160 ctttgttgtc agcagcattg acaattattt cgtcaaatat cttgtaaagg cctggaacat 8220 aggtcactgc tttgtaatcc agcttgttct tctcagagtc aaagacccac atttcagaag 8280 tcgttggctc aatactgcca atgtatgtat ccggacgtct tagcacatgc tctctcggtg 8340 taagacgctg gtactgtgta gatacattag aatttccatt tccgttgttg gtaactagtg 8400 gtatctgttc agaagctgtc atggatgtca agctagtttg ccttaagtca ggagtgcttg 8460 ccttcttggc gcgagacttt gaggatgttg tagatgcttt ctaaaaaagt tgttagtatt 8520 ttaaaataat aataaattcc acaaacactt gcataccctt ttggtggttg tgttaggtaa 8580 aacgttttcg tctccagacg cttcatcttc atagtcggag aaatccgcat caatggacat 8640 agtttgtaaa attaagttgg aaatatgtag taaatcaaag gttattccaa cgtgtaaacg 8700 ttattattaa aaaatcaatg gatataataa tgacacgctt taagcaacgt caaataacaa 8760 aattaagata tgtaagaaga gaaaatgata tttgccctta gtatacgata ttaaaaaacg 8820 aatggagaag tgacctgaaa aaaaagtaat ggataaaaaa gaaggtagaa cgaatgaata 8880 ccaaatataa tgttttttgt taatttggat taattttttg gtttaaaaaa gtattaaata 8940 gatattcaag cgtttatatc accacagact gattcacgta tgtagaaagt cggtcaaagc 9000 aaacgcgtga cgaaaaacta atagtatgat ggaaacttca gagattgtat gtatgatagt 9060 actaatttaa atagtttgtt taaaagctct aaagggctat gtgttcaact atcccaacaa 9120 tgattgaagt tggtagctgg tgaaggatag gaagagagaa cagaacataa gtagatagaa 9180 gttgcaaccg aggaattgat tactacggaa aaagaaaaag aaaattattt ttaagaataa 9240 atagcaaaag aaaggatttc taaatttccg tgcgttatta atatagggat gcgcttaaaa 9300 cataattgaa gtctgtaaaa aaaccgtatt tggaacatat gctgtaacta atttgtaaag 9360 caaatgtaat aattaattaa ttgtataata aagaatgttt gtgctttgaa attaaaattg 9420 aaattcttgg tgctatttta tatagtatgg aataaacaaa ggattttgaa aatggaaaat 9480 gaatgtttag ataaatccat aattcatgag tatgctcgca aagattgtaa aagaattgag 9540 tgacctatta cagttggtca tttgaaagaa aaacgctaaa cacgataaaa agagatgaac 9600 ggaaagcaat gatggaaaca gaaactgctt ttttaaattc ttcttgattg taccatcagc 9660 attaatccat attatttcga ttaagctgtt cttgaaacat tgttgtatgt aactatcatt 9720 aagttcaaac aatttaatag taattttgtg aatatagctt ctccctctat ttaacaattg 9780 caggtatgaa acaggaacaa aaacatagaa agaactctca aacaacagac tcatctaata 9840 aatgcaataa acttttttct gaaaatctta aaagaagctg caaatgtaac aaaaaatggt 9900 aggcccagca gatagctgat gcatgggttt aagtatttcc attatttatc gatgttgcca 9960 accaattccc attaatggac gaaaaatagt gtgaagtcga ttgtttaata aggagagtta 10020 caaaatggaa gcgcaagaca aacgcatatt cggagtcact ctttcaaggt ataagcaagc 10080 attggatagc caaaacgaaa tgtgtaggat ctgagcaaga aaaatgcttt ttgaagtatc 10140 tcagacagct gctcataagt cagtaagcga taaattattt aatggaagaa aagagtggat 10200 caatagatcg gcggcttctt tcattggata ttcgcacaaa atgttaattg acctaaattt 10260 gagccatcta acataaccat cacttcccta atttcctgtg tataatagtc caaaaaaacg 10320 gaatcggaca tcgcgaacat attccgctcg atcagagcag atcaaaaggt tgattcttca 10380 gtgtcccaca ttataaggct atttctcgct taccaaggaa cacatcagac ctcctgaact 10440 tatcctccac caacgtcctc ttcattttaa aattcatttt attgaaaaaa aatcatattt 10500 ctagctatct tgcacctcta tttggccttt gcttatcccc ggatccacgt tggatatttg 10560 ctcgcctatc gaatagtata ttaaaaaaag ttcgcttgag aaaaaaatta tttgtcaaag 10620 tcgaaagtgg aaagacgttt ttaaaagaag tattttgtgg caaagaagtc aatatctaag 10680 aagaaaaaaa gtttcggttg atctgtaact aaaatcagcg tcaaaatagc atcaccaata 10740 cgtccgagtg agaagcatca aggttcctca aaatcaagaa aaactttacc aatattactt 10800 ctattgtttt atctagcatt aaaaataatt tcatttaaat acaatcctag agcgggattg 10860 ttgaaaagaa acccaaccta atcttagttt atttgaattt gctcagctaa ttttgaatgt 10920 gactatattg aacactcaaa ttggctaatt cttcgtttaa caaacatcga aaactattta 10980 tttcttccca tctttttgtt tattaaaaaa aaaagaaagg agaacaataa cagaattcaa 11040 ttcatagttg tcggcggata ttgtttttct atccttttct aatccttttg tgtgtactat 11100 ttgttttatg ttataattta ttaaaaaatc agaaagtgtt ttcgatatgg agtcttgtac 11160 aaggtcttca ctacagcagc ttgtcgcagc tgactcaaaa tcttctaact tttgtttccg 11220 gaatttatcc caatcatcga ataataatgt atcatatgcg tcttcaagca atcgcaattt 11280 tgttccccaa aatgttctca ataatgagta ccaatctttc cagcattctt caacatctca 11340 accttccgta cttcgacaag gaaaaaatgc ttttttaaag ccaagccaac tgtctttcaa 11400 tatgaattcg tccgaaattt ctaatacgca ttgggcacgc gattttaata ttctaacttc 11460 taactttgct tcgtcctccg ttacttctgc tcctactcaa tcctcacata tttcaaactt 11520 tactaattct caaaaatatt ttgcaaacga tcttcccaac tctctaactg accaaccctt 11580 agctcagcca tcggcatctc aacgttctac atggctacct tgttctgcag ccgttagcac 11640 ttcaagtcct tcatctgatc ccttctttga ttcttatctt gaacaagctt tcgaaaaggc 11700 tgaacgactt gcaaacgaac aacaaaagat ttccaaagtt gagaaaacct ttggcacttt 11760 ggattccata ggtactgaac aggatgattg ctttgatcct gattacagca atctccccct 11820 ttttcctcag gaaaatgcat ctcccccttt gtttcgaaaa gcatcttgca acagtggttt 11880 taccacaaaa tgttgattag gagtttcaca ctagcttact aatttccctc ctaaagattg 11940 cttcaactga agtgtagcat tgcttcagtc gtatttcaat atttgatttt tttatgcctt 12000 atttttttgt tttaaaattc ttttcgctaa aatttgcttc gagaatctat caatacaagt 12060 tctctcttgc cgcactataa atctcaaatt tagctttcaa aatcatctat ttattgcagt 12120 gtatacattc ataataccct catacctagc aatttcaaaa atccgtaact atagcttagc 12180 gatgcaaaag cacttccaca cctctttttg taaagaataa aattaatttg aatttttaac 12240 acttaattta ataataataa aatgttttgt acaacttgga ttgctacata tgggaaaatt 12300 caatcgtccc ttctttccag taatcaacaa ccacttaata actgccaact cctaaaggtc 12360 gagcgcttga ggtgtctaag aggcagagca tgagcaaatc tgctttcaca agcaaaagtc 12420 agcttaaagg aatagagtat gtttacaaac tttacgtctt ttgtctagtg tactaacggt 12480 aattaatagt ggaagtttta atgacccatt tcggcaaccg tctatgaatt tgcctactcc 12540 ccctcatgat gatggtcttc catcaatacc taggtctaca gccttgccta atttgtctaa 12600 ccgattatct ccatattcgc atcgtaatta cctaccaatt cctgaagcgg attctcgtaa 12660 tttagaggtg cttaattcaa tttcgctcac aacaggatca gtcgtgaatc aaataaataa 12720 actttaccag aggagttgtg ataatgctaa ttacttacaa gacttacgct ctttaatact 12780 tcaaactccc acggctgaag caaatgccac ccaagttacc gaatctctaa accaaatcca 12840 aaaaatttta caagaggctt cttctaaaga tagagaacaa attgttcaag ttattaaaga 12900 actcaataaa ggtaacagtt tggaggttcg tagagaactt ggaaattgtt tggcccatct 12960 taagaaagga actttaaata tagacaacgc attacaagcc tctctacaaa aatactggaa 13020 agaattgcag tactttaatg tgtcaaagga taagttgcta tctttagagg aaagtataaa 13080 attgttaagt gcaagattag aggaaactga tacaccctcc tccactcatt ggatagagat 13140 aaatgctgga tttaaagaag ttggtgacga attgagcgag aattttcaaa gaaagcaaga 13200 aattttgagt ggattacaaa ataatgtgat tcttcgtact aataatagga agcctgtagg 13260 cagtgatggc tctaattcta attttaatgg tggagaagaa cagatggact ccaaagatca 13320 agaggaaata caagattatt tgaattctct tttgtcagtt catgagaaag atggtgtact 13380 tctccagaaa tttcataatt cttatgttca atatcagaaa ctcgctgttg cattgtcgaa 13440 atatgagaat ttcgatgctg ataagctgtt tcaacagatg aatttagcca agcaaagcaa 13500 tgagactctt ttacaaactt tgaccgaaca aaccgatcaa ctgctttcgt tcaaggaaac 13560 catggactca tttaaattta ttttaggtcc ctctatggag aaccaggctt tacagcaggg 13620 aattctagca gagcagcaag atttggtagc ccagttacgc gatattgtgc ttcgctcaga 13680 gacgctagct gaaaatccct ctaatatgcc cggtagttgc cttcctggag cctcctcaaa 13740 tactgctgac gagtttactg aacagctgaa tctacttaag aacgaagtag cacgcctctc 13800 tgcaatctgt ccaagcccta attctggaat taatgcttct gtgcttacta atgctgacaa 13860 tttagagaaa gagaacctcc tgttagtgaa caacaatgcc ttcaaagtag atgatcgttc 13920 agtgtcatca gttgcattag acgatcataa tcggcagtta caaatgaacg tagaggagtt 13980 agaaggaaag aaggcggatt taaccagcaa aattaatcga ttggataagg actttgttaa 14040 gctaaataca acctactcgt tactcaccga tcaagtcaaa actaagcaat tggcactcca 14100 agagattgaa agtcgagtta ttcgtctgga agaaagacta aatatgttac agaagctgtc 14160 catgcagcca gctatttctt cgagcagcga atttgttccc attgaatccc atccctcatc 14220 ttcagctgtt gtaccgatag aagaaccaaa aaatagtatt atagaaaaga agcgtgttcc 14280 acataacgct gcaagaaatt ctgttaattt ggaggtcact cttcctaatt ctaaaaagag 14340 gttttcttcg ttttctggat cttccagtaa actaccagtc cgtccatcaa ctgcgttaac 14400 agacaaaagg aaaccatctt ggtcaagaag gctagctgct gcaatcgggt tttcttcagg 14460 atctccagaa aagaagcatg tcataacttc atcggacgcg ggacatcagc gatctaaatc 14520 aagaagcttc agttctaaaa tgtaattata cgctctttta taggtcaatc gtttttgtaa 14580 gattatacca atgctattat ttaatcaatg actttcgttt ctgtactata cctctttcat 14640 atgtatacta cgttgaaata agcacttaat gtaaacaact attgaaagca gctcatcaca 14700 tgaagtccaa aaattactac aaccctttat ccctttaaga gctttacgat cgaaaatccg 14760 atttgccaat ggagatacaa atcagcgttc aaatatgaga aagtctaact atacagataa 14820 gcttcaacaa tccttgtaat actaatgtta agatatcttc agaaaattaa ccggtagtta 14880 acaaatagat gctatgtata ttgcattcat tagtaagcta gcgaccccat ttgctcagaa 14940 gccctttctt tagcttcgca tagacatata ccaacggaac gaatgacacc tggcagtgaa 15000 aattcccttt atactttgtg taagaatact aaagcttgtt aattttttta ttgatttgct 15060 aattagtaga ctccttgtcg aaatttggtt cgttaacatc agttcagcgc acttttcaaa 15120 cgatgaagtg tcaggtttta agcctaaaat tttcaccaag tttaatggga gtccattcaa 15180 aagacgtgat atggaatcct tcgtgatgtt ctgatggaaa gagaggtatc gcgaattatc 15240 actcggatcc atagatttta aaacttctga tgattcaatg aaatgaactc caggttctgc 15300 atacaatagt ggcaaatata gcttacgaaa gaaagctatt tgcttagaaa caatattttc 15360 aacttttcga ggattttcgg cgaaaaagga cattcgaata tcgccaaggt aggataaact 15420 tacaatcgtt ttgtaaagat cgaactctgt gaatcggtct gctaacatta acaggccaac 15480 gtgtaaggca ctacttaaat tataagagtt ttctttgtaa aattcatctt cccctttaag 15540 tatgacaacc tatttgttca aattcggtta atatccacaa ttgtagcaga agtctgttta 15600 tttaacttac gggtttttga aagcgccccg ctagatacat agtattccaa tttttaagat 15660 cttcataaac atcttttttg ctagtaacac catatttgat tatatttccc tctacttcca 15720 catgtgtatt gtagtataca ccggtgccaa aagattcttg aagtgttgac acgaaaccag 15780 gtccaaaatt tttaacaaat gaataatgag aagggttttg ctgcaaattt attttgtgcc 15840 acttgactgg gtcttctacc tgaaatataa aatcaatcat gggattctcc tagcagagac 15900 ataagttaga agttttagat taaacgagta taacgattaa taattactat ttaccttttg 15960 agaatatcca gcttgcctaa agaccccgct gccataacct acggcgacat caatgggagc 16020 ttgaaagtaa ttaacaacct ttgtgagatt ttctttcaat tcttcttcag gttgaattct 16080 ttggttttca aacgtaagta aattttgctt caataattgt gccactgtac atttcgcatg 16140 atgactataa ctatgacggt tcatccatcg ttttgttgaa tatcgaagga tattataaga 16200 aagaaagtgg gttttaccaa agatcatata tatgataaaa tacgagttag caattgcttt 16260 tttagttgtg atactataca gtgtttaatt atactgaatt ttggtcacga tgaggtacta 16320 tatgacagaa gacgaaaacg cccagtctac tcactcattg gactctacac atttcatcaa 16380 taatatttaa ttgaattatt tatttagctg tttttttata ccatgataaa ttaattattc 16440 aaaatgtgaa attaaaacca gagtatataa acttagaact gacttacata tgttcttact 16500 acttctaaaa gaaacgacat taaaagaatg aatcgaaaca taaaaattta ggtcaatgtt 16560 ccatcttttt tttttcgtag tttatattag aagattcaaa gatccaaatc tgcgtacatt 16620 tttacagcaa ccagtttcaa tgttcaaaaa agaaattgta gatcatcaac tgatgcatat 16680 ttattcaaag aaaccgactt gttctgcttt ttcttagtaa aattggttgc ttgttatgtt 16740 gcattgtata ctatacacga gaataaattc caccataatc aaaaaattga actgagaaaa 16800 aaatttgaaa acccaaacca tagaaacctt ttataacacc attaaataga aacttagaat 16860 tatttttgaa taccaacaac atgcctttca cgttcttttt catagggcac ggcacctttt 16920 ttactatgac ggcgaatgtt ctcttcacgt ctctttagag aattaatctc ttcacgtttt 16980 atttcggcag cctttttgac attagttgga agatgacgat gacgggcaat acggcgaatt 17040 tcaggaatat gcttatagcg ctctcgcaat gagtcaagat atttgaggcg attctcctca 17100 cgagtagagc gaattgacgc acgggaagaa gcacgagctc tccaaagacg aacattacta 17160 tcatcggaac cagagaatat gtattgtgca tccattgaaa atttaactgc agtaactcgc 17220 tgcatacgtt ttgtatgata aacatcacga ctatgaccct cccgaacatt gtaaattcga 17280 atcgttttgt cataagaacc actaacaaac tcttgacctg tcggtgaaaa atctactgac 17340 ataacggcag aaacgtgatc cttataaacg tgtaatgccc gctttaaatt tcgcatatcg 17400 tacatataca aattgtgatc ctcactgcca gctacaaaat taaatgcctc cattggattc 17460 caagaaattg aattagttct caatttggta atcaatttgg ttaacggtga tgatgtacgg 17520 agatcgtaaa ttacgattga tcgatccata ccagctgaag ccaaaaccga tgtttccgta 17580 tagttaaatt tgactaccgg taatgtatca gctccccatt caaactttgt tactggagta 17640 tcacgagaat agtcccaaat agatacattt tcaccgctag ttgcaaataa atcacctcct 17700 ttgctagtgt caatatccaa aagagaagag tctcccaaat acgatctttt aactttgcca 17760 tcttgtttat taagcatgta aacatagcga tcagaagcgc aagataaaac gtctccttga 17820 ttagagaata ctaatcccct aacaatgcct tcatgtgcct ttgaagtcca gcgctcacaa 17880 cgttcactag catcccatag ttttacagct agaaaatgtg ttagtgacat ccaaactttt 17940 tatatccact tatttatcac ataccaccat caccacttcc actggcacaa tctatcaaag 18000 tttttgtatc acgagctaat gaataaacac catcttgatg tcctctaccc aattgaccaa 18060 gaaaaggggc tgcgaacatc ctgtccatct ttgtagcatt caatgcacgt gtatactcac 18120 gcgcacgttc aaaaggatgg agcgatggat ctaaattcct tttaacagga tcttgatcat 18180 taagacgtgt caacgaagta ccacgggtga ttgttttgac cttcatcctt tttggttcgt 18240 tgcaagtttc aatttctagt agtaagctct acaccttgca aaaatattgg ataatgaggt 18300 gtagcgtaaa ccatcgtatt tgaataaaca aaagggcaaa tacttcagca atccctaaga 18360 tttagctttt taaaactcat ttcaattatt taaaaattct actaaaagta atcttatcga 18420 actactagca aacgccacag gtcacaaact tcccattctt ttaaaacgtt cattttaatc 18480 aaagctaaat ttcacgagtg ccactgatga atctcaatca tatacaattt tattcttcca 18540 taaacagtgc aactgtcacg agaaattacc acttttctct catccaaata tttttttaag 18600 aaaccaataa accaggcatg cccagagtta atgcatatca atttattcgg agtgcttgcg 18660 tacaccagaa acaatatcgt ctacgcgcaa taagaggcaa gcactttcaa tcgcggtctt 18720 aattgactgt aatttgacgg cttcaggttc ccaaacaccg tactcatgca tgtcgacaac 18780 tcgaccagtt tccccgtcaa taccaaagct atgttgacct tccgcatgtt tcgcgcgaag 18840 ttcggtaagt gctttaattg gattggcacc gcaattctga actaaagtac gaggaatgat 18900 ttcaatagca tctgcaacag ctcggtaagg ccattgggca acgccctcaa tagaacgtgc 18960 cttttccgca agacgaacac tgacagccat ctcagtagca ccaccgccag gggaaagttt 19020 aggatggaag aacacatttc tggctacagc catagcatcc tgtaaattgc gctcaacctc 19080 attaataatg tctttacttg gtccacgtag taaaatagta catgccttgg gatttttaca 19140 gcctgttaaa aaggtataat actcatcacc taatttatcg atgtaaaata agccacagcc 19200 tgtacctaca tccttctcac gtaaatcttc aagacgatta acgatattgg caccacacgc 19260 acgagcaata cggttgttat cagatttacg tgttcgacgc agagcagtaa tgttagcttt 19320 taacaagtag tgttgagcaa ggtcagatac acctttttca gtgatgacaa gatcaggttt 19380 tactgcaatg atataatcac acatacgctt gacttgttct tcttcaattt caagaatacg 19440 gttccaatcg gtgtctttgg aaatttcaat attagtttga gattcacctt ttcggtactc 19500 taaaggacaa tccaacagga caattcttgg attttctatg cgacgacgca ttttgggatg 19560 tgtaacatct ttgttaagca taacaccatc taatacgcag cttgactcaa tttcaccacc 19620 tgggaccttt tccacacggg cataacgctt aatgtctatt tccattctac catttgaagt 19680 agaagcaacg gtacggacag cacgaagagc aagatgacac atcaaatcgc tccatctcgc 19740 aactaattta gtgccgatac atgttcgaat aagacgaaac atttcagcat tgtcatcgac 19800 attcacgggt aacgttatct catcaataat agataatgca tcttccaaag cttgtttaaa 19860 cgagcggatc atgacaacgg gatgaatttt acgatcaagc aatggactag cagcggccaa 19920 tatttcacca gccaatataa tcaccgaagt agtgccatca ccaacttctt catcttgggt 19980 tctcgcaagc tcaatcatgc ttttagcagc cggatgtgcg acttcaattt cacgtaaaat 20040 ggcatgtcca tcgtttgtaa gcaaaacact cccaactgga tcgagcaaca ttttaagcat 20100 agctctcggg cctaaacatg ttcgaataac ctataatgtc agcaacgtaa tatataacaa 20160 acctcagttt aaagcttaag aggatggaaa aaaaccgtac atcagcgaca gccttcgcag 20220 cttgtatatt tgacatctgg gccttgtggc caacctgtcg gttgccattt gtatctttgg 20280 ttaattaaat taataccaga aatgcaactt actcataaca aacacaggag actgcatgtt 20340 ggtgaaagac aacttcaaat tggtaaaggt cgtttgttcc ttaaagcgaa gtattcaaaa 20400 ccctgataag gatacgttaa aattcgcaat aatagcaaac cgatacgcaa attttgtttt 20460 gcaaatgtta ttgtatataa aaatcaaaaa gataacgaga ttgaccaaca cagaagcgtt 20520 tttatttact ttgagaaaat gattagtttg ctatatttca tattaaaata aattgaggta 20580 aattaataat tgaaaaaaat tgtaaaattt gatattaaat aaaacaaata tgaaaataca 20640 tctgctctct cattcccaga acttcgaaca agagaagcag aagtcaaaag tggtagtaat 20700 ttcatggatt aaagtaaaaa aaaaaggatg tgtacaacct atcgaaatat atacctatac 20760 tcacaatgta cacatgaaaa ataaacacag atatcgagaa ttagcttata gaagataatc 20820 aatttttatg caaggtcaga aaacaccgta ttatttctaa caaatcgaaa gcaataatgg 20880 ttcaatacgt ttatgtacca ctgtggagga gtgtcaaaaa aaaatcaaac ctgtagggta 20940 attcagaaga aatggtaaac gatagatgaa ccgttcgaat atatacaacg ggaagaaaac 21000 aagcatatat acaatcatag aaaaagattt gttttacatg aaatattcta actttttatg 21060 ttagtttttc gaagaaccaa acaaccagaa acatatactc aatgtagtca cgcttaccaa 21120 agcgcacaag gatacagcaa gtaaataatt taaggcgtaa gattgtcaat ttgtgaaatt 21180 gtgagttgaa tatttgagcg gattttctcc aattcttgaa ggggcatcag agcactaggt 21240 tcaggatcca ttttttcgca agattcaaaa aggcgttttg attcacgatc tagcgcagat 21300 atcatagtag gtaatcgggg aaggacctct gaaacttgat tgatttgttg gttcaaaact 21360 ctcagagagt cattaagtgt tttatcaaac tcagacaaaa ggtgctggga cgtttcgtac 21420 aatatagaag ggtcattgct ctcaggaaga agctgattta atttatcaat tgggctcttg 21480 aatttcgagg gaccaaattc cccaatccaa tccttctcgg gcattgatat ttggcgtctt 21540 tcttcaagta gccctcgtct gttttccttt tcttagttct ttccgagatc cttcgtttcg 21600 gtatactaaa ttatatatta tggtcgagag tggtataatt ttaatgaatg tcatacgcac 21660 ctcgtaataa tgtactattg agcattgtcg atccacctta taactagatg cagaaagtgt 21720 gcttaacatg gctttatgaa tactaacgcg gtagctaatc ccattcaagt ggttttgaaa 21780 tttgtatatt cgctttagca atgtcccaag aaaaccatgt ggatgtccct aggaaaagga 21840 ttcggattga ccaatctgag tcttcaagga atttggaaag aaatggatta gaagatgaag 21900 ccaacgctcc ttcagatttg agcggtcaga agttttatat gaccgagtca gatgtaggaa 21960 ttgatgcgtt tttgaatcca aatcttcctt caatcgatgg aattattaaa gcaagattca 22020 cggattttgc tgtttttgaa gttgatacag atggaaatat agttcactta actgatatgg 22080 aagctcacga tcctatcctt tcgaaggcaa ccggagacaa ggaaactgaa gacgcaaaag 22140 attcttctaa tcaagatata agtaatgacc agaaagctcc ttcttttaag gaacaagaac 22200 ctgctacact gcctatattg ccgaatgacc tccaaagtat catacctaag ggaattggta 22260 atgaatttat tcaatctctt cataagctat cagttggtga aataactgat cccatctcat 22320 taattcttcc cgaaaatact cctcctatgg ataaaggtca gcgaacgatc ttacatcaat 22380 tcatacgaaa caacttttct ggactcgagt cttctacaaa agggaatgga acttttacag 22440 tgtcaaagac caccagaaaa aaccagccta gatcacgaag agatccccga ttaagttgga 22500 aggctttggg tggtgaatat tgccatttcc atttgtataa ggagaacaga gattctatgg 22560 actgtcttgg taaaattgcc cgcctcctca aagtccccac taggacttta tcaattgctg 22620 gaaccaaaga tagaagaggc gtaacctgtc aacgcgtagc tattcatcat gttagagcat 22680 ctcgactcgc acaattaaac tctggttctc ttaaaaattc cacatatggt tttcttttgg 22740 gaaattattc ttataaaaat tcaaatttaa gattgggaga cttgaaggga aacgaatttc 22800 acattgtagt gcgtaatgtt attacgccta aagagaaggt tgttgaagca ttgaattctt 22860 taaaagagca cgggtttatt aactattttg gtttacaaag attcggtacc agttctgtcg 22920 ggacacatac cattggagtt cgtcttttac aatcagactg gaaaggcgct gtcgacctaa 22980 ttttatcacc aaggcccgag cataccggtt ctgtcaaaga agcaattgat ttatggcatt 23040 ccactcatga tgctgaagct tctcttcgca ttcttcctcg aaggatgata gctgaatcca 23100 gcattttgga aacatggtct cgatctggta atcaaactga ttatttagga gcgttccaga 23160 gaattccccg tcacttgaga agtatttacc ctcatgcata tcaatcttac gtttggaaca 23220 gagttgcttc ttggcggata aagaatttgg gcgatcgtcc tgttgtggga gatttggttt 23280 actctactga gtctaatggt ttaagtcaaa aaagccctat tgttgaccca gaggcacctg 23340 atcttctaga agatttacct gtgagctcaa aattatcagc tcgtccgatt gaagaggacg 23400 aagtcaataa ctttagtatt tacgacatag tacttccttt acctggtcgt aatgtaatat 23460 acccaaaaaa tgaaactttc gatatataca agtctgtcat gaatgaggca tcacttgatc 23520 cattaaatat gtctcgcaaa gacagagaac tttcattacc tggtgattat cgaaaacttt 23580 tggtgcgtcc tgaaaatatg gagtttaatt tcataaagta tgacaatatg gaacaacaac 23640 tgattttgac ggataaggat agattggaga accgttctat ttcagtgagt tctgaggttg 23700 gtaagcacac cgctgttacg ttaaaatttg tacttccatc ttctgcttac gctactatgg 23760 ctttacgaga agctttaaga actgcaactg ctagtggtga tcaacgtatg ttgatgccag 23820 cggtacttaa agattcaata taaaatttat tagcttaaaa gaacacagct ttgaataaac 23880 ttgggattat ggcgattata atagaaattc attttaccta cggaagtttt ttgcttattc 23940 ataaatgatt aagcgttaat tcgacgatct ctaatttaca cgttggatta tataaatcac 24000 atgtatcatc aatgtaacat tcacttgtat actttagaaa acgattttca tttacctcat 24060 taaccagaca ttttttgccg tatttatata tacaatcact aatcactgcc accgaaagga 24120 atggacggtg gagggggtga ggattaaaag cttaatatga gttcattttt ttcgagagat 24180 cgctaaaatt ctttttagaa tggctgttaa atcagccgtt ttgttcatct ttattaagtg 24240 catctcggga gcggcctcaa tctgaccatt aagctcatca tcacccaagt caccttccca 24300 aacagtatta agccatgaac aaggttccca ttgagacgtc aaagtctgag ttccttccaa 24360 gtatcgggaa tcggcagata agtaggataa atcttggagt atacatccat ggcgatttaa 24420 aagaacttga atgccatgat ttttggatag gataattctg tactgacgca gagatcgagc 24480 caaaacaacg tagcccaatt cttgagctac taaaacacct ctcgttctat ccataattac 24540 gcgtaatggt tgaatagctg agggcccatc agaaaatgta tcctgcaaaa actgagaaat 24600 tagatgaaac ggactatgtc gattaaaaaa atgaagggta aaagtgttgt cgtcatgaat 24660 tgtagcccta aatttctcat catcgagata tgtaaagtcc acatgcttta acgtgataca 24720 atctacattg aatgcagatg ttttagacaa agcaacaagt ttaagtaatc caatccatgt 24780 tttttcgaaa gatgaaaaat tttgcacacg aatggtaata cgaccggttc tccaatctat 24840 gtagcagttc ttttcagttt cagtctcaga ctgatacggc aattttcctt ttattcggga 24900 gtcaaaaatt aactgcccgt catgcgcgcg aacgaaaacc acaggaagca tatcttcatt 24960 agacgatggc atcataatac ataagcatcc tgtttggacg tatgtagtaa agtcatcttc 25020 aattagggct tttggtggaa taggcaaata ttcaaaaggc ataccacgag cttggcaagc 25080 agtttgaaca ttgaataaaa gtatttggac ttccaatagg tacgaaagac ggctaaaact 25140 ttcaatactt aaagtacctt ttgtagtatg aacatcttgg gtgtagagag tttgacccgc 25200 agcgttcaac aatctaacag accaagagtt ggattcaacg ttgtacgcga gtacccatag 25260 ggaatcgcca tcttttctcc atttaccttt ggagaatgta agataaggga aagaatagta 25320 accttgaact gcatgcaact cagcacactg ggcaacttct aatagctgcg tttgtataca 25380 aaagaaatac aaccgattca agatttgggc gggaggttgc gtattcaaag caatattttt 25440 ttcagcagca cgaagatgcc tgggaggtga taaaggtgaa gccgaactcg acagcacgag 25500 cctgccggta acgctgttca ccttgacaat tatttcatta tcaaagacat gaatttttag 25560 accaccacca acatgttcac taaatatatt tgggtgaagc tccttacgga tttgttccag 25620 aataagttga gcgtgttttt gggtaattaa taatagtaga tgctgagcat ccatatgatc 25680 atctaatggt acatgttcaa caatgccatc atggtgccat tcaacgagta ataaaaaatg 25740 atcatattca caactggatc tcttagagct aagggtacgc tcaaaggcgg atatgggttg 25800 agtatttaca aatatatgaa tataatgacc aatttttccg ggttttcctt cttttttcac 25860 atttaattgg ggccaatagt atagacgtag ccgtgggggc ttttcatcat agacaccgcg 25920 caaatgccct aaccaacttt ctctggatag ttgaaaagtt tgttgtgaca ataaattaag 25980 gcgctgatat aaacaaaatt tatgaaggat attatatatt aaaggtagga tgggcttttg 26040 tagaacgaat gcagcagcga tttcttcatt gagatgcaat tctataaaaa cccgatattt 26100 tgcgggagta gaagaaaaat caggaagatg aaattgaaag tcaacaacaa tccactggaa 26160 tgaaataccg gtagatttag gatc 26184 //