ID SPBC1861 standard; DNA; FUN; 23851 BP. XX AC AL109834; XX SV AL109834.1 XX DT 13-AUG-1999 (Rel. 60, Created) DT 06-SEP-1999 (Rel. 61, Last updated, Version 2) XX DE S.pombe chromosome II cosmid c1861. XX KW abp2; ars binding protein 2; carbohydrate kinases signature 1; KW conserved hypothetical protein; elongin c homolog; KW eukaryotic protein kinase; leucine rich repeat; KW regulator of transcription elongation; RNA recognition motif (x4); KW RRM, RBD, or RNP domain; ser/thr protein kinase; KW similar to C-term of yeast U4/U6 splicing factor PRP24; skp1 family domain; KW u2 snrnp-specific a' protein. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-23851 RA Oliver K., Harris D., Lyne M.H., Rajandream M.A., Barrell B.G.; RT ; RL Submitted (13-AUG-1999) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk XX DR GOA; Q9USX7; Q9USX7. DR GOA; Q9USY2; Q9USY2. DR GOA; Q9USY4; Q9USY4. DR GOA; Q9USY5; Q9USY5. DR SPTREMBL; Q9USX6; Q9USX6. DR SPTREMBL; Q9USX7; Q9USX7. DR SPTREMBL; Q9USX8; Q9USX8. DR SPTREMBL; Q9USX9; Q9USX9. DR SPTREMBL; Q9USY0; Q9USY0. DR SPTREMBL; Q9USY1; Q9USY1. DR SPTREMBL; Q9USY2; Q9USY2. DR SPTREMBL; Q9USY3; Q9USY3. DR SPTREMBL; Q9USY5; Q9USY5. DR SWISS-PROT; Q9USY4; ABP2_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c1861 is overlapped at the 5' end by cosmid c56F2 and CC at the 3' end and by cosmid c14F5. XX FH Key Location/Qualifiers FH FT source 1..23851 FT /chromosome="II" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c1861" FT /map="IIR" FT misc_feature complement(1..98) FT /note="nominal overlap with cosmid SPBB56F2 S. pombe FT chromosome 2" FT misc_feature complement(25..30) FT /note="gtaagt, splice donor sequence" FT CDS join(complement(1954..2030),complement(1566..1873), FT complement(31..1458)) FT /db_xref="GOA:Q9USY5" FT /db_xref="SPTREMBL:Q9USY5" FT /label=SPBC1861.01c FT /note="SPBC1861.01c, len:612, LOW SIMILARITY:Homo sapiens, FT CENC_HUMAN, centromere protein c, (943 aa), fasta scores: FT opt: 229, E():9.5e-06, (21.3% identity in 507 aa)" FT /partial FT /gene="SPBC1861.01c" FT /product="putative centromere associated protein" FT /protein_id="CAB52737.2" FT /translation="MTMNETSAIPARQRENQFFEIGVVGRKTGFTVPRDVKKGDDGFED FT MDAYFLSDGSIHLDEDNGDIEQDMPPVTRLQPTSPMAVNAASDEASHASSSDSSDKNPD FT IPSSPLLMNSRALRASRGSSGPLIVPIDHSAFQAEDEGTADKTKVDGNKLSIQPRKANR FT IVDFSRIKASPDRKKFEPRRSTELPSKIPSSTPKDDNVQESPAFPDENITALQKNVANF FT TSIKDSGGRDNLYIQTISKPRRSYVQNNKSEQTIKPSKQNKQKEEKKTISQGNKPNSRD FT EDSELSIDVPLSMLNRSLANNSQKNKKRTPNKPLQESSINSVKEGESNPVVKRKRGRPR FT KNKLEIGNSVQTSEATQVKGAKKPAIRNAKKMSNEKDDSLNSQSDSASGEFIKTIARNN FT LQEIKQVEREDTLVGVRRSKRTRIAPLAFWKNERVVYELHRDENRIPALPEVKQIIRVD FT DPSPSIRQGRKKRHAKRSGVEIKSNLEAKSNDVEEYDAFYKDEINCEVLSWNEQNPKAS FT EERVVGYSLPSVNLQQISNQQLKFASLFKEEPSFAAGVVEMPAGAEKPVKPSKHNIMSF FT CILQGKIEVTVNATTFRMKKDGVFIVPR" FT misc_feature complement(1459..1474) FT /note="ctaattatacatacag, splice branch and acceptor" FT misc_feature complement(1560..1565) FT /note="gtaagg, splice donor sequence" FT misc_feature complement(1874..1894) FT /note="ctaaaaaatatttttatctag, splice branch and acceptor" FT misc_feature complement(1948..1953) FT /note="gtacgt, splice donor sequence" FT misc_feature 2031..5163 FT /note="low-complexity gene-free region" FT CDS 5164..6747 FT /db_xref="GOA:Q9USY4" FT /db_xref="SWISS-PROT:Q9USY4" FT /label=abp2 FT /note="SPBC1861.02, len:527" FT /gene="abp2" FT /gene="SPBC1861.02" FT /product="ars binding protein 2" FT /protein_id="CAB52738.1" FT /translation="MNFYSLLPSRHDVSADNITEKFCQFCLCCNPWYAGADTRQLANAF FT NMIPKSEGQKFEIWVLFLLVRQYHQKIINSWSKLVGFLGVERKDEQSTQKIQQYVVRLK FT RWMSQTHVDAFFDYLLNKPNPYYLEIPETQPQVRCNVNVTDDLVIKSLRAGLMSHPDVN FT SSSISTMRTSTSPSNWIHSASASLDDNTHNLGSFVTNPHADSQECPTPQSLLMRASHHM FT SERGSQQAHQTTPQNHSLPHPPNMFEPPDEDHQLPSAANNSHNHDHAFQTAEAVGVADS FT IDPDWHQWPDDLRDVSSPKESDGLNDSWSRQTNQVETENVENEAGVPRKRGRPPGARNK FT IKRLRSEPSVSLTLSISWYERFEKLMHAQNTMLRSAFSHVARLPMETVSQLLSHYTETI FT SQYLPPSETSPIPKTPNFKFISSTLLALVSSHSEILEASTDRLIWTVHQGPLTATICHA FT FNLEKAPSMHSLAEAQMIPDVPISHSNSMEPLDTVSSLKLEIAKLNAALKEKNLELENL FT KRKIMNAVFD" FT CDS join(7181..8875,8921..9352) FT /db_xref="SPTREMBL:Q9USY3" FT /label=SPBC1861.03 FT /note="SPBC1861.03, len:708, SIMILARITY:Saccharomyces FT cerevisiae, MK10_YEAST, glucose repressible protein mak10., FT (733 aa), fasta scores: opt: 229, E():1.3e-07, (22.4% FT identity in 539 aa)" FT /gene="SPBC1861.03" FT /product="hypothetical protein" FT /protein_id="CAB52739.1" FT /translation="MSVKESLSLLNSMQGNVKIGNVEPAKGNEGYVDNAGYVDCTKSYF FT EATKSLKEEQLVCDPKFTLLDSISAFEIMEPKMDSGIDYQPLRVDFSRDLSYLEILALM FT DLIVSAEKEWHYGSPLSESLLCSAHVFSICKSPISQVGDSGFSSGSGRNTTDIVLFPFV FT LAVIKCCDIVHREFLMGNLYDEEDISSFSYHMSFLQNYPIEKLNYLLQSSIEYLASEVI FT KFSAELRQIIEGILNRIQLRIGILRVYERSDIKTTIDALHLIKNLVPEIQNTVSVVDSS FT IKESILKQYWDFRVQAQLVATAPVRNIPPTGIEHSYQRILYFADDMLLILNSHTLASSL FT AVYQFCLDFTRLNRTPEPYVRSSLQALITANNAVNLRDQPTSYMLECIREFSGLPSNFY FT NPNTRTVIEKNSISSAYGPLVESLIAHSTNIMVDLVRICSHNPCRFRRNLINLLPEITV FT AHFEAEALDLKFVAKSLPSNGPFSSFIYHVKLNAIEHILLSSFEQKLHQPYQWPHFFAV FT LDHVFSIHQTHLELHGKDRNTPPMAKTFVTYLHRILNAIKETYSGYLLLTVLCMRLNII FT KTPSFTLDEKIQESYYMAHYRPLINLRQPKPLLRSEADCIIKNLQNFSTDDLIIKSNEK FT FTAAKNSLINVIKSGFEQNEFINPYFLQTNYLKNLLCCCITNLVSLAILSKDHSANLKI FT VEIPGNPLPSLSRT" FT misc_feature 8876..8881 FT /note="gtatgt, splice donor sequence" FT misc_feature 8908..8920 FT /note="ctaacgattttag, splice branch and acceptor" FT CDS join(complement(12438..12669),complement(12048..12313), FT complement(9443..11989)) FT /db_xref="GOA:Q9USY2" FT /db_xref="SPTREMBL:Q9USY2" FT /label=SPBC1861.04c FT /note="SPBC1861.04c, len:1014, SIMILARITY:Ophiostoma ulmi, FT Q01491, colony 1., (826 aa), fasta scores: opt: 751, E():0, FT (29.9% identity in 539 aa)" FT /gene="SPBC1861.04c" FT /product="similar to C-term of yeast U4/U6 splicing factor FT PRP24" FT /protein_id="CAB52740.1" FT /translation="MSQIQDLKDENVEMDIDPQEQNEKKPLLLDELTKFTILHPYNYDS FT HIKLIEELKRLDKKKELSEARKTFQSIFPLSEDLWVDYLLDECKNCRTLDDYVRIKTLF FT DLAVQDYLSIKIWCMYLEFTLNLMDTSSFEQEQSELNGVITLTDAHSLFERAYQTCKFH FT FSKSQCVWTLYLEFLQTFGDALFEGEEEQEIVFKNKIYDFHIDRLKLPHEQIEETFTSL FT STFVTNNWSPSEYEDVMVKSNKVYETTLKRNAKIFNKELLLNSANHSLEAYMDLINDES FT RRSTAELQYITTLYERAIVLYPLIPELWLQYTAWLSKVDFSSSQASSVAERATRNCSWI FT GRIWSIKLTYMTLSGASTSAVCEEKDRCLNSNLLVNFDEVIDFFSGFLKACLYLSSNED FT KPQEFLKHQIHKVEDYLRKNHKGSKDARMRIELSKIYLYSEISDFESVEKCWSDMFHDF FT QNQALYWISRYISTMKYNPELAAETLKKSLYKNVDQPQLLFQFYQSIMDLNNDCFTNTS FT HLYDVLNAQRISFKRQLDSFAEETKQTVENTEPLKVPQADDTAALSKKRKPGQEGDVFK FT KSKPIEQHRNREELTVLVTNLPSDISENELKIFFKDCGNIIRIFILEDNQKDVKVAQIE FT FSETSEVLAAKTRDLKSIRGHEISVQIHVDTNLYVTNFPPTYDELDITKLFSAYGNVVD FT VRFPSLRYNTNRRFCYVQMRKPDEAHNALQLHKKLLEEKYPIQVFISDPLRRTPRSGAV FT YEGRELYVTNIDFKVNEKDVETFFRDYGQVESVRIPKRFNQHKGFGYVVMTTNQDAENA FT LSAAGKQLGNRVLNVVLSKPRESLEKTRVSSNDNRTLAKSFETTESNKMSTPKKSFEQI FT KSKSLGVTNVDGTVNEARLRSLFESYGKLYRVVLHPEHEGAVVEFLDIHDAGKASLALE FT GHEIGGRLLHITTVNEMMHNVPSSMNHSDYNTSATRPRRLGSRTFQGFNSNHSNINSKK FT DDLDDKEMQIDAPKSNDDFRKMFLK" FT misc_feature complement(9665..9856) FT /note="Match to PF00076 rrm, RNA recognition motif. (a.k.a. FT RRM, RBD, or RNP domain) Score 27.56" FT misc_feature complement(10007..10213) FT /note="Match to PF00076 rrm, RNA recognition motif. (a.k.a. FT RRM, RBD, or RNP domain) Score 70.27" FT misc_feature complement(10289..10486) FT /note="Match to PF00076 rrm, RNA recognition motif. (a.k.a. FT RRM, RBD, or RNP domain) Score 54.97" FT misc_feature complement(10508..10714) FT /note="Match to PF00076 rrm, RNA recognition motif. (a.k.a. FT RRM, RBD, or RNP domain) Score 34.78" FT misc_feature complement(11990..12006) FT /note="ctaatcaatgtttacag, splice branch and acceptor" FT misc_feature complement(12042..12047) FT /note="gtaagg, splice donor sequence" FT misc_feature complement(12314..12327) FT /note="ttaatggtttttag, splice branch and acceptor" FT misc_feature complement(12432..12437) FT /note="gtatgt, splice donor sequence" FT CDS 14013..16256 FT /db_xref="SPTREMBL:Q9USY1" FT /label=SPBC1861.05 FT /note="SPBC1861.05, len:747, SIMILARITY:Escherichia coli, FT YEIN_ECOLI, hypothetical 32.9 kd protein in nfo-frua FT intergenic region., (312 aa), fasta scores: opt: 884, FT E():0, (50.3% identity in 304 aa)" FT /gene="SPBC1861.05" FT /product="conserved hypothetical protein" FT /protein_id="CAB52741.1" FT /translation="MLIVMNRGCRLVSRIPLGFRRLKRNPNPGLRNILCRRYSPLALSK FT EVTEALKNNVPVVALESTIITHGMPYPQNEELAIQVESKVRSMGAVPATIALLNGQCTI FT GLEQFQLSELAKSGETAYKVSRRDLSYVASQRLNGGTTVAATMILARAAGIDVFATGGI FT GGVHRGAENSMDISADLIELGRTRVAVVSAGVKSILDIGRTLEVLETQGVPVVTLGPPK FT SAFPAFFSRESKFQSPLSLETPQLIANMLFSNIQLGQECGTLVAIPTPHHCSIDYEKME FT ALIETCLQRSVQLGITGKNVTPWLLGELLRESKGKSLNTNIDLVLNNAEKASLIAKELA FT VLKEKSSFFPTNTGNTFETKPVKQDFFYGKVSDKGVSSSKKKITETTSKPAEVVCVGSV FT SIDSVLKLDNPLTSKFLGTSHPCHSEQAFGGVAHNMALASSLMGASTKLVSCVGTKSVP FT TSSIKEYLTKSSLQHTIVEKSNFTSCSYTAINDCNGNLLLAGADMAIMENLSYSEIKDD FT LNDAKYICFDGNISPSLMLDITTSKSSKQRVVFEPTSGPKTLKILKVLSVASIDFITPN FT KFELDVLFQAMKDGNFFENESWWQKLNSFGITSSFYNEIERFTKSTGIEEITENGILQK FT CFHLLPFIKNIIVKLGPNGALLISSEKLQGVNSNSASLFTPGNVTVKYYPVPKVIATPV FT NASGTGDTFIGTFTALLSKGWGMDDAIDTAQKAAGLTLQCNFSVNPEIKTLLK" FT misc_feature 15297..15371 FT /note="PS00583 pfkB family of carbohydrate kinases FT signature 1" FT CDS complement(16305..17606) FT /db_xref="SPTREMBL:Q9USY0" FT /label=SPBC1861.06c FT /note="SPBC1861.06c, len:433, FT SIMILARITY:Schizosaccharomyces pombe, O13699, hypothetical FT 50.4 kd protein c11g7.06c in chromosome i, (430 aa), fasta FT scores: opt: 441, E():3.9e-22, (25.7% identity in 385 aa)" FT /gene="SPBC1861.06c" FT /product="hypothetical protein" FT /protein_id="CAB52742.1" FT /translation="MDNQQRKVQGSSSNTFIKRAFQHLKSLFTVCFTGADYLESDIELI FT CQNEIQPQGLEKLNADSSNFYCNSLTSNQSLTTSMEALDLSSSLTTPHADKLLKLSNLI FT AAKSFTTERKLSAAEFLDSREIHNPFTYGFLGILYGTSRTPYLHAQYANSFMSESAVPI FT SIELNNREAKASMNLAEKNFPEGFEDFVSFLENPNIPLTVLLHHVMLYDLYSNNLKDAV FT WVAVTNYMKNLVGNYGYTELHIRAAQQMFGHPRFLLVHPEDIYCISGSSDWVCVSTQHF FT HCNIHVHSVSGNAIRKSRNPIIQDLSSICQNSTEFGWLALTHALRKKGAIFPIHAYLNF FT NAKLYEECIPPSILYFNKNDENINVGNIEDITNYMYETFINEASLCDKFMKRKHERIET FT PLSSQGREISNTLSRKRGAKGSNPFEIENMMPHA" FT CDS join(18146..18251,18292..18340,18384..18517,18556..18560) FT /db_xref="SPTREMBL:Q9USX9" FT /label=SPBC1861.07 FT /note="SPBC1861.07, len:97, SIMILARITY:Drosophila FT melanogaster, O44227, elongin c, (98 aa), fasta scores: FT opt: 269, E():8.2e-14, (47.9% identity in 94 aa)" FT /gene="SPBC1861.07" FT /product="putative regulator of transcription elongation, FT elongin c homolog" FT /protein_id="CAB52743.1" FT /translation="MEKEYVRLISGDGFVFILEKEIACLSGTIRAILNEGIFSEAQKNE FT CTFPDIRATLLEKVCEYLHYNYRYKNQLDIPKFDIPPEMVLELLVTAEYLEA" FT misc_feature 18155..18436 FT /note="Pfam match to entry PF01466 Skp1, Skp1 family," FT misc_feature 18252..18257 FT /note="gtttga, splice donor sequence" FT misc_feature 18281..18291 FT /note="ctaatgtatag, splice branch and acceptor" FT misc_feature 18341..18346 FT /note="gtatgc, splice donor sequence" FT misc_feature 18368..18383 FT /note="ctaataaggtgtctag, splice branch and acceptor" FT misc_feature 18518..18523 FT /note="gtaaga, splice donor sequence" FT misc_feature 18543..18555 FT /note="ctaatgaatacag, splice branch and acceptor" FT CDS join(complement(19447..19525),complement(18751..19391)) FT /db_xref="SPTREMBL:Q9USX8" FT /label=SPBC1861.08c FT /note="SPBC1861.08c, len:239, splice donor is incorrect but FT no alternative available. Homology shows that position of FT intron is correct but cosmid sequence has good coverage in FT this region. This region will be checked by sequencing PCR FT products primed from genomic DNA. SIMILARITY:Salmo salar, FT CAA06160, u2 snrnp-specific a' protein., (339 aa), fasta FT scores: opt: 653, E():0, (44.5% identity in 238 aa)" FT /gene="SPBC1861.08c" FT /product="u2 snrnp-specific a' protein" FT /protein_id="CAB52744.1" FT /translation="MRLNAEFLSQVPSFISPLKETELDLRWYQIPIIENLGVLRDVHDA FT IDFTDNDIRYLGNFPRMKRLQTLLCGNNRITAIAPDIGKVLPNLKTLSLAQNHLQEIAD FT LDPLASCPQLTNLSCIDNPVAQKQYYRLYLIWRIPSLHILDFERVRRNERLRAEEVFGQ FT IQNPTEIASSIMGVKSRVFDLAALVQSHPEANSPITTGYTLTPEEREKIKEAIKNASSI FT AEINRLEAMLLEGKIPK" FT misc_feature complement(19199..19264) FT /note="Pfam match to entry PF00560 LRR, Leucine Rich FT Repeat," FT misc_feature complement(19265..19336) FT /note="Pfam match to entry PF00560 LRR, Leucine Rich FT Repeat," FT misc_feature complement(19392..19408) FT /note="ctaactcataattacag, splice branch and acceptor" FT CDS 21118..22698 FT /db_xref="GOA:Q9USX7" FT /db_xref="SPTREMBL:Q9USX7" FT /label=SPBC1861.09 FT /note="SPBC1861.09, len:526, SIMILARITY:Neurospora crassa., FT O42626, protein kinase nrc-2., (623 aa), fasta scores: opt: FT 1698, E():0, (53.3% identity in 514 aa)" FT /gene="SPBC1861.09" FT /product="putative ser/thr protein kinase" FT /protein_id="CAB52745.1" FT /translation="MARETEFNDKSPSSTDDGMSQSHFSDKLKNLFHFRRNRAATVSTS FT VRNDQRDNDSDDSTFDINVNQLNELDLNDSSDQLDSRPSLRRVSSAPDSHKGVEAPPPR FT PLINMSNIRKAQVKILKNPGNYIFGRTEYGKRTYSGNSTKISRVEVTPHSFEKIRLLGQ FT GDVGKVYLVRQKSNHRLFAMKILNKREMIKRHKVNRVLAEQEILTKSKHPFIVTLYHSF FT QSRDYLYLCMEYCAGGEFFRALHSLPKHILPEKDACFYAAEVTAALEYLHLMGFIYRDL FT KPENILLHQSGHIMLSDFDLSKPISIVTHPTVVLPKHSTFSQEKPALDTNSYFSNFRTN FT SFVGTEEYIAPEVIRSCGHTVAVDWWTLGIFIYEILYGTTPFKGKNRHATFSNILYSDV FT SFPEYHGAPNVSSTCKSLIRRLLVKDESKRCGSVAGASDIKQHPFFRHIQWALLRSMKP FT PIIPKIEDGMEAVEPSDNDNEEEDFLNSQYLISANLPAVDMHSSTPVNEQSNPFDSFSS FT VTLHHAGDE" FT misc_feature 21580..22452 FT /note="Match to PF00069 pkinase, Eukaryotic protein kinase FT domain Score 301.96" FT CDS 23226..23851 FT /db_xref="SPTREMBL:Q9USX6" FT /label=SPBC1861.10 FT /note="SPBC1861.10, len:208" FT /partial FT /gene="SPBC1861.10" FT /gene="SPBC14F5.01" FT /product="hypothetical protein" FT /protein_id="CAB52746.1" FT /translation="MKRSYKDIIRFLKLIGISHSTAIKLVDGILPVMIGLKTSYLVDCV FT FLEISELREIIEFVGPDCLRGIYFTEPISQCFVLHVANWEEWSSIDSLVPIVVDLPSKK FT QNRLLQSCITKHVDRLLDLCKRNLSTFTIDISSSWRQNIIENNEQKEFECTSTAITGCL FT LNYGATYNYDHTLFKDNGLSCETLKLYTLEVHSKKKDVSDTLIQFS" FT misc_feature 23742..23851 FT /note="nominal overlap with cosmid SPBC14F5 S. pombe FT chromosome 2" XX SQ Sequence 23851 BP; 7314 A; 4353 C; 4098 G; 8086 T; 0 other; atttttagaa atgtgtatat ttaaacttac cccttggaac aataaatact ccatcttttt 60 tcattcgaaa agtggttgca tttactgtga cctcgatctt tccctgtagt atacaaaaag 120 acattatgtt gtgtttcgaa ggcttcactg gtttttctgc tcctgctggc atttcaacga 180 cgccagcagc aaaagatggc tcctccttga acaagctggc aaattttagt tgttgattag 240 agatttgctg gagatttaca gaaggcaatg aatagccgac tactcgttct tcagaggctt 300 ttgggttttg ttcattccaa gatagaactt cacagtttat ttcgtctttg taaaaagcat 360 catattcttc aacatcattc gattttgctt ccaagttact ttttatttca actcctgagc 420 gctttgcatg ccttttcttg cgaccttgac gaattgaagg tgatggatcg tcaactcgga 480 ttatctgctt tacttccggt agtgctggaa ttcgattttc atctctatgt aattcatata 540 caacacgctc attcttccaa aatgctagtg gtgctattcg tgtacgtttc gaccttcgga 600 caccaactag tgtatcttca cgttcgacct gtttaatttc ctgtaaatta tttcgagcaa 660 ttgttttaat aaattctcca gaagctgaat ctgattgtga attcaatgag tcatccttct 720 cgttggacat cttcttcgcg tttctaattg caggtttctt tgcgccttta acttgtgtag 780 cctcactagt ttgaacagaa ttgccgattt ctaatttgtt cttacgaggt cgaccacgtt 840 ttctcttgac tactggattt gactcccctt ctttaacaga atttatgctt gattcttgta 900 aaggtttatt aggtgttctt ttcttattct tttgagaatt gtttgctagg cttcgattaa 960 gcatagaaag cgggacatcg atagaaagtt cggaatcttc atctctagaa tttggtttgt 1020 tgccctggga tattgttttc ttttcctctt tttgcttatt ctgtttagaa ggcttaatcg 1080 tctgttctga cttattattt tgaacataac ttctacgggg ttttgaaatg gtttgtatat 1140 aaagattatc gcgaccacca ctatccttga tactagtaaa attcgctaca tttttttgta 1200 aagcagtaat attttcatcg gggaatgcag gcgattcttg aacgttatca tccttgggcg 1260 tagaggatgg tattttggaa ggaagttcgg tacttcttcg aggttcgaat ttttttctat 1320 ctggagatgc ttttatccta gaaaaatcga caattcgatt tgcttttctt ggctgaattg 1380 ataatttgtt gccatcgact ttcgtcttat cagcggttcc ttcatcttcc gcttgaaaag 1440 ctgagtgatc tataggtact gtatgtataa ttagtaattt tatcaatgaa atgaaacgga 1500 aagtaacagt agagtatttg aggagttgta aaataaaaat ctgtgatgcg tagatagaac 1560 cttaccaatt aaaggaccag acgaaccacg gctagcccga agagctctcg aattcatcaa 1620 caatggtgaa gaaggaatat ccgggttttt atcactagag tcagaagatg aggcatgaga 1680 agcttcatca gaagcagcat tgactgccat tggagacgta ggttgaagtc ttgttactgg 1740 cggcatatcc tgctcaatgt ctccattatc ttcgtccaaa tggatggaac cgtcggaaag 1800 aaaataagca tccatatcct cgaatccatc atcgcctttt ttaacgtctc tgggaactgt 1860 gaatcctgtt tttctagata aaaatatttt ttagtaaatt tattaaaaaa agaataatta 1920 ttacgatata tggaacccaa ttcgcgaacg tacctgccta cgacaccaat ttcaaaaaac 1980 tgattctctc gttgtcttgc cggaatagca gacgtttcat tcatcgtcat tattctatta 2040 aataaacatt aagtaaaaat atagcctaaa tagccaaaca aaacaatata tggggacgta 2100 agtgttgtct ttcttgttta cgtgtagtac aggatgtaca ttatgtgtca tggaataagc 2160 ctatcaatca gacccatgcg aaaaggcaag gtgtattcat ttttgcttcc agtataacta 2220 accaatacat ataaacttaa ttgcctaagc gcttttctgt ttttctgaat gcattttata 2280 gttatataat gttaggcaaa caaatacgaa attgcgttgg aaatgaaact tactagtgct 2340 gacagcgtag attacggtaa acagaaacaa acatgcctcc ttagaatgaa ggtcagaaag 2400 ggaattccag agaagaaatg aaccctacct agaagcatat taagtagccg ctaccaaggg 2460 atgaacccaa atagtggaaa agacggattg agcaattgac attcaaaaaa acggcctacc 2520 gcaataacaa tttaagagat taaaaataga tttatcattt tttataattt ttttattttt 2580 gggatttctt ctggcttggc catccaattg atgattgttt attaacttac gattatatta 2640 gtgctaaacc accattattt attacagtcg gtgttattaa gcgtattgct gacgagattt 2700 tttttcttgt atgaatccaa atttgcgatg ctacgccttg actgttttct ttttttcacc 2760 atagtatgtg aaaattttct gatgccgaaa tctcagcaat ggtgaaattt tgccaaaaaa 2820 ggggtcaatt gatcttgaat agggctgaaa aaaaaattca aaagtaaata aaattaaata 2880 tatttattta caaaaagtta agtcggtttg gtttttcgct tctcttttta caaaattttt 2940 tattatttta ttatttattt attaatttta tatctagcag atcaatattt agcaagccac 3000 cccgtacaat aattaaaata gctcttttca tgacatagta agaagactaa agtgcgaaac 3060 atgttcaatt aacgccaaga aaatgcttcc gtttacgcct ccttcaacca tacccgaatt 3120 ttttactcaa aatttatgta cgtacttttg gctgtattac aagaatccat agctaacctc 3180 tgtaaaagga tatcacctta tacacaaagg ctaggttatc ctgctaccac tataaagaaa 3240 atgaaagttc ccataatgaa gtctgtattt tgaatgtata ttgtcacttt atttcgccta 3300 caaccttcac gcgaactcag caaaaaaggg aaaaccctat tttacagcgg cttcaaatca 3360 ggtccttatt agtgcgacca attggccttt cttccttaaa atggcgattg ccgtttaagg 3420 aatatcacta gaagccgtta gcagctatta tttaaattgg tagtttcaac aagtaaatcg 3480 aagaaggcat atctctttat actttgagtg gcaactcaag aaattgttaa aattagctgt 3540 taaaaatttg ccataaatat agagagtgaa tgtcgttttg tttactaaca gtagtactca 3600 tgtactctaa tctaaatagc tgtttatttc caaaaaaaat agttttatag cttattattc 3660 gtaataatta gtattcaacc ttagatttgt aatatgcgct ccgttgcaaa tgcaaaaaga 3720 tactattaga gaagagccga ttttttaaat tctcgatgcc gctggatcat ttccactgtc 3780 tgtctcatta tttattctgt ttttttatat gattcgattt tatttgtctt tttcatttat 3840 agcattggtc gattgaaatc aaaatttgca ttttttgtat tccattcggg ttgccgccaa 3900 tgtgtgcccc tagtgtgtgc ccctagtgtg tcaggtaaat aacagcagtc gagacagcgc 3960 aataaccatt gctttacaga aatgagtagt aaatctgtaa taatctttga actcttgatt 4020 gaaacatttt taatttattg cctctatttt ttaatgcaat cccgttccat ctttcctcta 4080 gcaatttctc gatctatcca aaagatatag ggagattgaa ggtgtcctaa tgtgcgatta 4140 cgtatccctc atcggtaaac ggcgcacgac tccgtttacc gacagtcgtt aagtaccttg 4200 attcagcgag tgctacggta acaacgggtt aaaggtatca tcttgttatc tgagtcggat 4260 ggcccaaggt atcacaatat atgaaggaaa aagagtactt tattcgcgtt tcccattttc 4320 tactctatct tccattccaa tatataaatt ggacttttgc tcgtgtgcaa gtttttcgcg 4380 ctttttattt atcgtttgta aattagattt aagaggtttc gcctctttgg aaatatcttt 4440 ctttgccatc cttcttttga aaaatcgcga aattgtatga ccgtgcaatt ttctttttct 4500 cgaaaagcta aacgccaagg taataggttt tcgtgagaga aactcttcca attcttaatt 4560 tcaattgtga atacaaccga ttgttggagg gtttacaatt ttttccgaaa atttctcgac 4620 acccttgcta tacgtgccat atagcttagg gacaccattc ttattttctt tcttaaagaa 4680 gaaaaacttc tgtaatacct tccgcatcct tttttcatca taggagggga tcaattgttt 4740 tcataatctg tgcatctttt cgtatagtgt agacgagcta cttcatgtca atacttctct 4800 aatttctaga gaagaaacaa acaaaattta acatctgtac ttatattttc ttttttttgg 4860 ttacattcat tctcttattt cgtttttttt gctttattta cctccattcc ctttttttag 4920 tgtacggaaa aaaaaacatc ggttcattta cagattggag tttaatttat agacagcaac 4980 tccttcctgt tccaagaact gatacattct attaaaatcc ctggatcttt tctgatattt 5040 atatactgtt aatctcttta ttcgacattg cttgtgtctt tctgtcgtgt ttacttaata 5100 atccaacgtt tatctatctg tctttttaca ttttttattg ttttttaaag caattaatca 5160 aggatgaact tttattcctt gttgccatct agacatgatg ttagcgcgga taatattact 5220 gaaaagttct gccaattctg tctttgctgc aatccctggt atgcaggtgc tgacacgagg 5280 caattagcaa atgcattcaa tatgattcct aaatcagagg gtcaaaaatt tgagatttgg 5340 gtcttatttc tccttgtccg gcaataccac caaaaaataa ttaactcttg gtccaagctg 5400 gtgggttttc ttggtgtgga acgaaaagat gaacaatcta ctcaaaaaat acaacagtat 5460 gttgttcgtt taaaacggtg gatgagtcaa acacatgttg atgctttttt cgattatctc 5520 ctgaataaac caaatcctta ttatctcgaa attcctgaaa cccaacctca agttcgatgc 5580 aatgtaaatg taactgatga tttggttatt aaatctttac gtgcaggctt aatgtctcat 5640 ccagatgtta actcttcctc catctccaca atgcgcacgt caacctcccc ttctaactgg 5700 attcattcag ctagtgctag tttagacgac aacactcaca atcttggtag ctttgtcaca 5760 aaccctcatg cagattccca agaatgccct acccctcaat cccttttaat gagagcgtcc 5820 catcacatgt ctgaacgagg ttctcaacaa gcacatcaga caactcctca aaaccattct 5880 ctcccacatc ctccaaatat gtttgaacca cctgacgaag accatcagtt accttccgca 5940 gccaacaatt cacataacca tgatcacgct tttcaaactg ctgaagcagt tggcgttgct 6000 gattccattg atcctgactg gcatcaatgg cctgatgatt tacgagacgt ttcttcaccc 6060 aaagaaagtg acgggttgaa tgattcttgg tctcgacaaa ccaatcaagt agaaacggaa 6120 aatgttgaaa atgaagcagg agtccctcgt aaacgcgggc gtccgccagg agctcgtaac 6180 aaaattaaac ggctgagatc tgaaccatct gtgtcattaa cgctaagtat ctcttggtat 6240 gaaagatttg aaaagttgat gcatgctcaa aatacaatgc ttcgctctgc attttcacat 6300 gttgctcgtc tgcccatgga aacggtttct caacttttat cacactatac tgaaacgata 6360 tcccaatatc ttcctccctc cgaaacttcg ccgatcccca aaactcccaa ttttaagttc 6420 atctcaagta ctcttttagc cctggtctct tctcattccg aaatccttga agccagtacc 6480 gatcgcttaa tttggaccgt tcatcaagga ccattaacag ctactatatg tcatgcattc 6540 aatttggaaa aagcgccgag tatgcactca ttagcagaag ctcagatgat tcccgatgtc 6600 cctatatctc attcaaattc aatggagcct ttagacactg tttcctcatt aaaattagaa 6660 attgccaaac tgaatgcggc cctaaaagaa aaaaatttag aactcgaaaa tttaaagaga 6720 aagattatga atgcagtgtt tgactgaaat cacgattctt ccatgcatgt atctatttat 6780 gcagtacact ttgcgactgc acgttccacg aactggtgca atttcaaagt tacaaaattc 6840 tcatgttcaa aaaagcataa ttgtttaaag tatttatttt gttttccttc tctttatttt 6900 ataaaaagtt tttagatatt ctactgctag gtgagatggg ttaccatcga gatagttttt 6960 tacctttgca gatacaagta aaataatttc aaattggatt tatcattgtt tttattatta 7020 ttgaaaaaat taccatctta tttactctcg aaaatgttat tgaacaagca tttttatgcg 7080 tggaattttt gttgtgactt acagagtaac acttttcatt aacccataaa ctagacgttc 7140 aatagaaaat tggtcaatat aggggtgttt tgtcgatttt atgtctgtta aagagtccct 7200 atcattgctt aattctatgc aaggaaatgt gaagattgga aatgtggaac cggccaaagg 7260 gaacgaaggt tatgttgata acgctggata tgtcgactgt acaaagtctt actttgaagc 7320 cacgaaatct ctgaaagagg aacagctagt atgtgatcca aaatttacat tattggattc 7380 aatcagtgcc tttgaaatta tggaaccgaa aatggatagt gggattgatt atcagccact 7440 tcgtgtagat ttttcacgtg atctctctta cttggaaata ttagcgttaa tggatttaat 7500 tgtctctgcg gaaaaagagt ggcattatgg atccccctta tcagagagct tactctgtag 7560 tgcccatgtg ttctccattt gcaagtcgcc tatttcacaa gtgggtgaca gtggcttctc 7620 cagtggtagc ggaaggaata caactgacat cgttcttttc ccttttgttt tggctgttat 7680 taaatgttgc gatattgttc atcgagaatt tctgatggga aatttatatg acgaggaaga 7740 cattagttcg ttttcatatc acatgtcctt tcttcaaaat taccccatag aaaaactcaa 7800 ttatcttttg caatctagca tcgaatattt ggcttccgag gttataaaat tttctgccga 7860 gttacgacaa attatcgagg gaattctcaa tagaatacaa cttcgaattg gtattttacg 7920 agtgtatgaa aggagtgata ttaagaccac catcgatgct ctccatctga tcaaaaattt 7980 ggtacccgag attcagaaca cggtttcggt agttgattca tctatcaagg agagcatatt 8040 aaagcaatat tgggattttc gcgtccaagc ccaattagtt gctacagctc ctgtgaggaa 8100 tattcctcct actggcattg agcattctta tcaacgaatt ttgtattttg ctgatgatat 8160 gcttttgatt ttgaatagcc acactctcgc ttcttccttg gcagtatatc agttttgttt 8220 agattttacg agattgaatc gtactccaga gccttacgtc cgttcctccc ttcaagcact 8280 tatcactgct aacaatgcag ttaatctaag ggatcaacct acttcgtata tgttagaatg 8340 tattcgtgag ttttctgggc ttccttcaaa tttttataat cctaacaccc gtacagtaat 8400 cgaaaaaaac tctatctcat cagcctatgg tccgctagtt gagtctttga ttgctcattc 8460 aactaatatc atggttgacc ttgtccgaat ttgttcccac aatccctgtc ggttccgccg 8520 taatctaata aatttacttc ctgaaattac cgttgctcat tttgaagctg aagcgcttga 8580 tttgaaattc gtagcaaaaa gcctaccaag taatggaccg ttttcatcat ttatttacca 8640 tgttaagcta aatgcaattg agcatatctt gctttcttcc tttgaacaaa aacttcacca 8700 accatatcaa tggccccatt tttttgctgt gcttgatcat gtcttttcta tccaccagac 8760 tcatttagag cttcatggaa aggatcgtaa taccccacct atggccaaaa cctttgttac 8820 atatttgcat cgaatattga atgctataaa ggagacctat tctggctatt tactagtatg 8880 tataaagctt atcgcttctt ttttattcta acgattttag ctgacggtgc tttgtatgcg 8940 gttgaatatc attaaaactc cttcatttac tcttgatgaa aaaattcaag agtcatatta 9000 catggcccat tatcgtcctt taattaattt gcgtcaaccc aagccactac ttcgttcgga 9060 agctgattgc ataatcaaaa atcttcaaaa tttctctacg gatgatttaa tcatcaaatc 9120 taatgaaaaa ttcactgctg caaagaatag ccttattaat gttataaaat ccggttttga 9180 acagaatgag ttcatcaacc cgtatttctt gcaaaccaac tatttaaaaa atttattatg 9240 ttgctgcatt acaaatctgg tttcacttgc aatcttatcc aaagatcata gtgctaatct 9300 aaaaatagtg gaaatacctg gaaatccgct cccaagtctt tcacgtacat gaggtgttgt 9360 tcgtctttta tgttaataaa tcaaaattat caaaagttag gttttcaata tttttttaat 9420 cattcaatct aattattgct gactatttta aaaacatttt cctaaaatca tcgttgcttt 9480 taggtgcatc tatctgcatt tctttatcgt ctaaatcgtc cttcttagaa tttatattgg 9540 aatgattgga attgaaacct tgaaacgttc ggcttccgag tcgccgtggg cgtgtagcag 9600 aggtattgta atcggaatga ttcatactag atgggacatt gtgcatcatt tcattgacag 9660 tggtaatgtg tagtaacctg ccaccaattt catgtccttc taatgccaag gatgcctttc 9720 ccgcatcatg aatatccaaa aactctacta cagcaccttc atgttcagga tgaagaacaa 9780 ctctatacaa ctttccgtag ctttcgaata aacttctaag tctagcctcg ttaacagtcc 9840 cgtcgacatt agtgactcct aggcttttgc ttttgatttg ttcgaatgat ttttttggcg 9900 ttgacatttt atttgactca gtagtctcaa agcttttagc taaggttcgg ttgtcattgg 9960 atgataccct tgttttctct agagattctc gaggcttcga caaaacaacg ttcaaaactc 10020 tatttcccaa ttgctttcca gcagcagaaa gtgcattttc agcatcttga tttgtagtca 10080 ttaccacata tccaaaacct ttatgttgat taaatctttt cggtattcga acactctcaa 10140 cctgcccata atccctaaaa aatgtttcta cgtctttttc atttacttta aaatcaatat 10200 ttgtaacgta gagttctcta ccctcataga cagcaccgct tctaggagtt cgccgaagcg 10260 ggtctgatat aaagacttga ataggatact tctcttccaa tagcttctta tgtaactgca 10320 gggcattgtg tgcctcatcg ggctttctca tttgtacata acaaaaacgc ctgttcgtgt 10380 tataccttag actaggaaaa cggacgtcaa ccacattacc atatgcagaa aataatttgg 10440 ttatatctaa ttcatcataa gtcggaggaa aattggtaac gtagaggttc gtgtctacat 10500 gaatttgaac agaaatttca tgacccctta tcgatttaag gtctcttgtt ttagcagcaa 10560 gaacttcact ggtttcagaa aattcaatct gagccacttt aacatccttt tgattgtctt 10620 cgaggataaa aatgcgtata atattaccac aatctttgaa aaaaattttc aactcatttt 10680 cgcttatatc ggaaggtaga ttggtaacca aaactgtaag ttcttcccta ttcctgtgtt 10740 gctcaatagg tttcgacttt ttgaacacat caccttcttg cccaggtttt cttttctttg 10800 aaagggcggc tgtatcatca gcttgaggca cttttagtgg ttcggtgttt tcgacagtct 10860 gcttcgtttc ttcagcaaaa gaatccaatt gacgtttgaa gctaatcctc tgtgcattta 10920 aaacgtcata taaatgtgat gtgtttgtga aacagtcatt attaaggtcc ataatggatt 10980 gataaaattg gaacagaagt tgaggctgat caacgttttt gtaaaggctt ttttttaacg 11040 tctcagccgc aagctctggg ttatacttca tcgtacttat gtatcgagaa atccaatata 11100 atgcctgatt ttgaaaatca tgaaacatat cagaccagca cttttctacg ctttcaaaat 11160 cagagatttc tgaatataaa taaatttttg aaagttcaat gcgcattctt gcatcctttg 11220 atcccttatg attttttcgc aaatagtctt cgactttatg aatttgatgt ttcaaaaatt 11280 cctgtggctt atcttcatta gaagacaaat ataggcatgc ttttaaaaat ccgctaaaaa 11340 aatcaataac ctcgtcaaaa tttacgagca aatttgaatt caaacatcga tctttctctt 11400 cacagacagc cgatgtggat gctccagaaa gcgtcatata agtcagttta atggaccaaa 11460 tacgcccaat ccatgaacag ttacgagtag ctcgttctgc tacactggac gcttgagaag 11520 aagaaaaatc cactttacta agccaggcag tgtattgcaa ccagagttcc ggaatgaggg 11580 gatacaaaac tatggcacgc tcatagagag ttgttatata ttgtaactca gctgttgagc 11640 gtcgcgattc atcattaatt aaatccatat acgcttcgag agaatgattt gcgctgttta 11700 acaatagttc tttattaaaa atttttgcat ttcttttaag tgtagtctca tacactttat 11760 tgcttttcac cataacatcc tcatattcgg aaggagacca gttatttgtg acaaacgttg 11820 ataaagaagt aaacgtttct tcaatctgct catgtggaag ttttaatcta tcaatatgaa 11880 aatcatatat cttgttttta aaaacaattt cttgctcttc ttctccctca aatagagcat 11940 caccgaacgt ctgtaaaaat tccaaatata acgtccaaac acattgactc tgtaaacatt 12000 gattagtaaa tacattttta tcatgaagaa aatttttagt tccttacttt agaaaaatga 12060 aatttgcaag tttggtatgc acgttcaaaa agagaatggg catctgtcaa agtaataacg 12120 ccgtttaatt cagactgttc ttgttcaaaa gaagaagtgt ccattaagtt tagcgtaaat 12180 tcaagataca tacaccaaat tttgattgac agataatctt gaactgccaa atcaaacaat 12240 gtttttatcc tcacatagtc gtctaaagtc ctacagtttt tgcactcatc taaaaggtaa 12300 tctacccaca aatctaaaaa ccattaataa atgcttgtca aaagattaac aaagttaaag 12360 taattagtga ataatttttg cgagtctatg gaattcgcct caacacgctt tacctagacg 12420 attgttgatt gacatacctt ctgaaagtgg aaagatcgat tgaaaagtct ttctagcctc 12480 tgacaactcc ttctttttat ctagacgctt taactcttca atgagtttaa tatgactatc 12540 ataattatag ggatgtaaaa tcgtaaattt ggtcaattca tccagaagca aaggcttttt 12600 ttcgttttgt tcttgtggat caatatccat ttcgacattc tcatctttta aatcttgtat 12660 ttgactcatt tcgtcaaaac cgacgaagac taggcttttg ctgggttcct taggtaaatg 12720 tcatgcgtat aatgtcaagt aaatttcaag ataaacacta aagtcttaaa aaacaagggg 12780 aagttaaatg gaaaaaagta aaaaagcaat tcgttaaaat actagaaaat attaaacaat 12840 ctaggttgat cctaatatac aaggcacatt gttaaaaggg agaaagagat taaaagattg 12900 aataataaaa cttgtaaaaa tatgcttcag aacaagatag cactacttag tttgctgtta 12960 atatctttta gtcatagacc taagttcaac cattttatga agtgatacat tttttcctga 13020 aggagggaat taacaacaat agtttgtaaa cagatataca tttgttttat tatagtaaac 13080 ttgtctgtca attggattat gtgaatatgg taaaactcaa aagtctggca aatcttgatc 13140 cttattttat cttttctgta aaaatgatag taatataatt ttttgggtaa agtaatttta 13200 cacttcagtc agcttaaaaa cctcttagta cttagaataa aaatatagta aataatgtaa 13260 aattctttta taaaaataat gaaacaattc gacaaattaa gccatgcaaa catcataaaa 13320 aattcagttc ctttcagaag aatgaatatt tatactttaa tcagaacatg gtttcacaat 13380 taaacacaat agataaaaaa gggtcatggc attggtttcc tggataaaag aagttctttt 13440 ttaaatagag ttgcatttta ttgcaactcc attcaaaatt caagtctatt gctttaatat 13500 gaattgtttt cgacaccaaa ataaataaaa gaattcaaaa aaaaactcaa ttccaagttt 13560 tgtatcagta aattcggagc gccggcaaag tattcagttt gcctgctctc cttttattta 13620 cattttacta taaagttatc ttgacatata tcggcgaagt aacatttttt gtgatcggct 13680 tttccatggg gaaagcgtac atttattatc agacaccacc atgtttagat atgatttgcc 13740 gaggtagatt atatataaaa aacgtcgtct gatcgttctg gcattttcat tttttgttcc 13800 ttaaactttt attcctaata gtatacgtcc tttttaaatc tcaattttgg gttaacttta 13860 ttccactcat tctttttacg tttattagat acgcggagtg agcgcgtata gtacgattta 13920 ttcacgattt taatattatc tgatatacgc tttcttcgtt tgtcctatat tatttaccta 13980 tttatcacta tttttcttag catcttgctt atatgctcat cgttatgaat agaggttgtc 14040 ggttagtttc acgtattcca ttggggttca gaaggctgaa gagaaatcca aaccctggat 14100 tgaggaatat actttgcaga agatatagtc cgctggcctt atccaaggaa gtgacagaag 14160 cccttaaaaa caacgtacca gtcgttgcct tagaatcaac tatcatcact catggaatgc 14220 cttatcctca aaatgaagaa ttggcaattc aagtggaaag caaggtacgc agcatgggtg 14280 cggttcctgc gacaattgct ctattaaatg gacaatgtac tatagggctt gaacaatttc 14340 agttaagcga acttgctaaa tcaggtgaaa cagcatataa agtgtctcgt agagatttat 14400 cttatgttgc ttcccagaga ctcaatggtg gaaccacagt tgctgcaact atgatcttgg 14460 ctagagcagc tggcattgac gtattcgcaa cgggcggtat aggtggtgtt catcgtgggg 14520 cagaaaattc catggatatt tctgcggatt taatagaatt aggtcgcaca agggttgccg 14580 tcgtcagtgc tggtgtcaag agtatactcg atattggacg cacacttgaa gtattagaaa 14640 ctcagggtgt tcctgttgtc actttaggcc ctccaaaatc ggctttccct gcattttttt 14700 caagagaatc caagttccag agccctcttt ctctagaaac tccgcagtta attgctaaca 14760 tgctctttag taatatacag cttggccagg aatgtggtac tcttgtggcc attcccaccc 14820 ctcaccattg ttctattgat tacgaaaaaa tggaggcttt gattgaaact tgtttgcaaa 14880 ggagtgtaca acttggcata actggtaaaa atgtaactcc atggctttta ggagaacttc 14940 taagagaatc aaaagggaaa agtttaaata ctaatattga tttggtctta aacaatgccg 15000 aaaaggcttc ccttattgca aaagaactag ctgttttaaa agaaaaaagc tcttttttcc 15060 ctaccaacac cggaaataca tttgaaacga agccggttaa acaagacttt ttctatggta 15120 aagtgagtga caaaggggtt tcgtcgagca aaaaaaaaat tacagaaaca acgtccaaac 15180 ctgcagaagt tgtatgtgtt ggtagtgtgt ctattgactc agttttgaaa ttggataatc 15240 ctttaacatc taaattcctt ggcacatctc atccttgtca ctctgaacag gcttttggcg 15300 gtgttgctca taacatggct ttggcttctt ctttaatggg cgcttctacg aagttggttt 15360 catgtgttgg aacaaaatcc gtacccactt cctctattaa agagtatctt accaagtctt 15420 ctttgcagca taccattgtt gagaaaagta actttacctc ttgctcatac acagctatca 15480 acgattgtaa tggcaattta ttattagctg gagctgacat ggccatcatg gaaaacctta 15540 gttattcaga aatcaaggat gatcttaatg acgctaagta catttgtttt gatggtaata 15600 tttcaccgtc attgatgcta gatataacca catctaaatc gagtaagcaa cgagtcgttt 15660 ttgaaccaac cagtggtccc aaaacattaa agatactaaa agtcttatct gttgcctcaa 15720 ttgattttat aacaccgaac aagtttgaac tcgatgtatt atttcaagct atgaaagacg 15780 gaaatttctt cgagaatgag tcatggtggc agaagttaaa cagctttggt atcacctcct 15840 ctttctataa tgagattgag cgttttacga aaagtacagg aatagaagaa attacagaaa 15900 acggaatctt acaaaagtgt tttcatttac ttcccttcat aaagaatatt attgttaagt 15960 taggacctaa tggtgctctt ttaataagct ctgagaaact tcaaggagtg aattcaaact 16020 cagccagcct ttttaccccc ggaaatgtga ctgtaaagta ttaccctgtt ccaaaagtta 16080 tagcaacccc tgtaaatgct agcggaactg gtgatacttt tatcggtact ttcactgctt 16140 tgctttcgaa aggctggggt atggacgatg ctattgatac tgctcaaaaa gctgcgggcc 16200 tcactttgca gtgtaatttt tcagtaaatc ctgaaataaa gactctttta aaatagttgc 16260 tctcattaac gatcgttaat aatgccgcga gaattcttta ttttctaggc gtgtggcatc 16320 atattttcga tttcaaatgg attacttccc ttagcaccac gcttccgact aagagtattg 16380 gaaatttccc ttccctgtga gctcaacggt gtctctatcc tttcatgttt tcttttcatg 16440 aatttatcac agagtgaagc ttcgttaata aacgtttcat acatgtaatt agtgatgtct 16500 tctatattac caacatttat attttcatca tttttgttga agtaaaggat tgatggtgga 16560 atgcactctt catacagctt ggcgttaaaa tttagatatg catggatcgg gaaaatcgcg 16620 cctttctttc ttaacgcatg ggtcaatgct agccatccaa actcagtgga attttgacaa 16680 atagaactta gatcttgaat tataggattt ctgcttttcc gtatggcatt gccgctaacc 16740 gaatgtacat gaatgttgca atggaaatgt tgagtagaaa cacaaaccca atctgatgat 16800 ccagaaatac aatatatgtc ttccggatgt accaacaaga accttggatg cccaaacatt 16860 tgttgtgcgg ccctgatgtg caactcagta taaccataat ttccaactaa atttttcatg 16920 tagtttgtta ctgccaccca cacagcatct ttaagattat ttgaatacaa gtcataaagc 16980 atcacatgat gaagtagcac cgttaacggt atattggggt tctctaaaaa cgaaacaaag 17040 tcttcaaatc cttcgggaaa gtttttctct gctagattca tacttgcttt ggcttctcta 17100 ttattcagtt caattgatat cggaactgct gattcggaca tgaacgaatt tgcatactga 17160 gcatgcaagt aaggagtcct gcttgttcca tacaaaatac ctaggaagcc gtatgtgaat 17220 ggattatgaa tttctcttga atctaaaaat tctgcagcag atagcttacg ttcagttgtg 17280 aacgatttgg cggctattaa atttgagagt tttagaagtt tatcggcatg tggtgtagta 17340 agagagctac tcaaatcaag cgcttccatt gaagtagtca agctttggtt tgaggttaaa 17400 gaattgcaat agaaatttga ggaatcggcg tttaattttt caagtccttg tggctgaatc 17460 tcattttggc atatgagttc gatatcgctt tccagatagt cggctccagt gaaacaaacg 17520 gtaaatagac ttttcaaatg ttgaaaagct cgttttataa aggtgttgct cgatgaacct 17580 tgtacctttc tttgctgatt atccattgcg actctagcca atatatgtat atatatatat 17640 ataatatcaa tataaaattt tgtatagcgt ctattcaatt aatgcttaaa atttatattc 17700 ttgaatggcg tatttagaga gtatgttata aatggatgat ttcagcatac caattgctat 17760 gatttgagga ccaaattagt gtaaacaaac tagttttgtc aacaaacaaa attactattt 17820 tgccagaaac caatttcgat atttttttaa cttaaatatc gttttaaatg atttctttaa 17880 cggttgaaat ttacattttc ccttttaatt ttagagaatt ttagtcagta atatattgtc 17940 ctctattttg attcaaaaga aaattaaatt caattttcta tattaaatta aataattatg 18000 ggtccggaaa gtaagctaaa taattaatgt ttactttcct tgctaccatt actttttcta 18060 cagaacacct aagacggtcg ggtattatat tttttttgaa attgacgtga taaaacgaaa 18120 tcttagtatt acacagtaga taaatatgga aaaagaatac gtgagactta tatctggcga 18180 cggctttgtg tttatattag aaaaagaaat tgcttgtctt tcaggaacga tacgtgctat 18240 tctcaacgaa ggtttgataa tgatatttag taaagtaatt ctaatgtata ggaatatttt 18300 ctgaggcgca aaaaaatgaa tgcacatttc ctgatatacg gtatgcaatt ggtctattca 18360 ttcaattcta ataaggtgtc tagggcaaca ctgttggaaa aagtttgtga atatttgcat 18420 tacaattaca gatataaaaa tcaattagat attccaaagt tcgatatccc acctgagatg 18480 gttttagaat tattggtcac tgcggaatat ttggaaggta agattatcat tactatttaa 18540 agctaatgaa tacagcataa ttctgattac tcacgaggaa cgaaaggatt gctaaattgc 18600 tacagcatta aagaattgac ggtttttgtt tacgattaac gatttgatgc cttaaataac 18660 tattaaacgc gttacctatc gaatgcaaga aatgagatgg aaaaaatgta ttatataact 18720 atgcggtttc tagaaatctt gtgagttact ttattttgga attttcccct ctaatagcat 18780 agcttccagt cgatttatct cagcaatgga agaggcattt ttaatggctt ctttgatctt 18840 ttctctttcc tcaggtgtaa gtgtatatcc agttgtaata ggagaattcg cttctgggtg 18900 gctttgtacc aatgcagcca aatcaaatac tcgacttttc acacccataa tagaggaagc 18960 tatttctgta gggttttgaa tttgaccaaa cacttcttca gcacgaagcc tttcatttct 19020 tctaacccgt tcgaaatcta aaatatgtaa cgaaggaatt ctccatataa gatataatct 19080 ataatattgt ttttgagcaa ctggattgtc aatgcacgac aaattagtga gttgaggaca 19140 actagccaac ggatctaaat ctgctatttc ttgaagatga ttttgtgcta gggataaagt 19200 ctttaaattc ggaagaactt tacctatgtc tggggctata gcagttattc ggttatttcc 19260 acacaaaagc gtttgaagcc ttttcatacg agggaaattc cctaaatatc gaatgtcatt 19320 gtctgtgaaa tcaattgcat cgtgtacgtc ccttaacact cctaaatttt caattattgg 19380 aatctgatac cctgtaatta tgagttagct ggatgacacg tagcatacag taatttcttt 19440 aaacatatct taaatcaagc tcagtttctt tcaaaggact gatgaatgag ggtacctgag 19500 acaaaaattc agcattaaga cgcatgaaat ttttgtaatg aaaatgcctt ttttatgctg 19560 ttactgcagt atgatttaaa attcctaaaa aattatccaa aacgctcaca atcctaaatt 19620 tcactattgt ttattcaaaa aatgttatag ttaacgtttt agaatctaat aatgtaaagt 19680 taattatgta aaaaccaaga atatgacacg tcaagagaag aagcaaagtg gtagagtttg 19740 gatagtaagc acataaataa atacaaagaa atcttgactc aataagcaaa aaatactcac 19800 tttttctact ttttagattt aaaaaaaaca aattatgcgt aattatactt tgataattga 19860 ctgacgactt ccatgttcaa gaatcggctt tcgtactaga aaattcttgg gaaaacagag 19920 aataaatgat ttttgtatat gtgtgttttg acacctttaa ataaaacatt ttttcattgt 19980 tgtcaaatat atatcttaag tttgtcagaa attggtacac actcttttat ctgttgagct 20040 ctcaaaaaca aacacaagca atcgactatt tggatgaaac acacattgtt ttccactcaa 20100 agttttagtt caactcatct ataatgttca tactgcctcc ctatttgact tcgtgagcac 20160 aaaccgccaa cgaaagtttg aaaccaggtt atttacaatt attcagagtt gcttaaggaa 20220 cctgttttcc tattaaaaaa ttgcattgag atacttacta aactgctata tctttttgtt 20280 ttctcattta atgaaaaaca ttccaaaaac aatattgaca tcaagtcgtt ttttaatgta 20340 acagttttaa tgaattcttc agattgtttc tatcgtattg ctctatctca atgaaagcac 20400 tgctaagaaa ttatatttaa attgatatga cagcttctaa tatcgaatca actatccatc 20460 ctcatactaa taccacatga gtcggactaa ttgaaaatgc cagcgatatc gacaaatgta 20520 catcgacatt tcggataatg tttgggttta gagtagcctc ttttgtagtt gaaagtggaa 20580 gaaatacatg attaaatgtt gtgcttccat agctcgtgta cttataaatc atacagtcac 20640 tcttgagaat atgaaattaa aaatcactgc atttattcta acacttattc tgttccagta 20700 agaattattc aaactgaatt tactacaaaa ctacagatca atacccacac ataaaaacca 20760 aaaacaagtt ttttctttta tttacaatag cttcaactaa gtattttgaa gctgcttgtt 20820 agttaatgct acaatatgac tgtttatttc tatatgctta aaaagaggat tatataacat 20880 aaggatggcc gtggctccac taactattct tttgccgaca cctccaaatg aaacaagaat 20940 taatataagc aggaggaata ccattcggct agttatatta gactatttgg gagctttgaa 21000 gtcgtttttc aagtttgctt acattctgat ttatattagg tattataagt gagccgtcag 21060 cgaaatttat taaccggtga atgtttgaag cgctacgaga ttaatggatg acttagaatg 21120 gctcgagaaa ctgaatttaa tgacaaaagt ccctcttcca ccgatgatgg tatgagccag 21180 tcgcactttt cagataaact gaaaaatttg tttcactttc gtaggaatcg agcggcaacc 21240 gtttctacta gtgtccgaaa tgatcagagg gataatgatt ctgatgactc aacctttgat 21300 attaatgtta atcaattgaa tgaattagat ctgaatgata gtagcgatca attggatagt 21360 cgtcccagcc ttagacgcgt atcttccgca cctgattctc acaaaggagt agaagcgcct 21420 cctcctcgtc ctttaattaa tatgagcaat attcgaaagg cacaggtcaa gattttaaaa 21480 aaccccggca actacatttt tggaagaact gagtacggca aacgaactta ttctgggaat 21540 agtacaaaaa ttagccgagt agaagtcaca cctcatagtt ttgaaaaaat acgtcttctt 21600 ggtcagggtg atgtgggtaa agtgtatctt gttcgccaaa aaagcaacca tcggctcttt 21660 gctatgaaaa ttttaaacaa aagagagatg attaaaagac acaaggtaaa cagagtcctt 21720 gcagagcaag aaattttgac caagagcaaa cacccgttca ttgttacgtt gtatcattcc 21780 ttccaatcta gggactatct ttacctttgc atggagtatt gtgcaggtgg agagtttttt 21840 cgtgcattgc attcccttcc aaagcatatt ttacctgaaa aggatgcttg tttttatgca 21900 gcagaagtaa cggctgcgct ggaatatctt catttaatgg gatttatata cagagatttg 21960 aagccggaaa atatattatt gcatcaatct ggccatatta tgttatccga ctttgatctt 22020 tcaaagccaa tttccattgt cacacatcca acagtcgtac ttccaaaaca ttctaccttc 22080 tcacaggaga aacccgcgtt agacactaat tcctactttt ctaattttcg cactaattca 22140 ttcgttggaa cagaggagta tattgcacca gaagtaatcc gtagttgtgg tcatactgtt 22200 gcagtcgact ggtggaccct tggtattttt atatatgaaa ttctgtatgg aactacacca 22260 ttcaaaggta aaaacagaca tgctacattc tctaacattt tatactctga cgttagcttc 22320 ccagagtatc atggcgcccc caacgtgtcg agtacgtgta agagcttgat ccgcaggctt 22380 cttgtaaaag atgagtctaa aagatgcggt tctgtcgctg gtgcctctga cattaaacag 22440 catccttttt tccgacacat tcaatgggcg ctgttaagaa gtatgaagcc tcccattatt 22500 cccaaaatcg aagatggtat ggaggcagtt gaaccttctg ataatgataa tgaagaagag 22560 gattttttaa actctcagta ccttatctct gcgaatttac ctgcagttga tatgcattcc 22620 tctacgcctg ttaatgaaca gagcaatcct tttgacagtt ttagctctgt cactcttcat 22680 catgctggtg atgaataaac ttactttgct attgtgtaac ctagaggcca tggaagttgc 22740 cttggctgta aaaagttttc accgttcccc ttttcccctt ttcgttttaa tttaaatagt 22800 tgtcttgaaa ttgatgatag taatgatcaa aatttattta taatctcaaa atgtgctgct 22860 atttattaaa tcgcaaccat atgttacata ttgcttgtag ctagctacta acgttaatac 22920 ctaataccat cttcatctct tgatggatat tttattttat tttttttttt ggtaaatggg 22980 gtagacttct ggcttctttt cagtcctaat taaactaata ttataagaat gttaacttat 23040 acttttcatc gatattatca aaagtgattt tggatagtaa atacgacagt ccattcttga 23100 tattggagca accggcattt ttcgactact cttaaacttg cttacttatg ctcattttat 23160 tatcattttt gatataagtt atcaaaatga tggataaaaa tatttaagat actttattaa 23220 agaaaatgaa gcgtagttat aaagacatta ttcgattttt gaaattaatt ggaatttctc 23280 attcaacagc gataaagcta gtagatggga tacttcccgt tatgatagga ctcaaaacaa 23340 gttatctcgt cgattgcgtt tttttggaaa tttctgaatt aagagaaatt atcgaattcg 23400 taggcccgga ttgcttacgg ggcatctatt tcacggagcc catttcacaa tgtttcgtat 23460 tgcatgtcgc aaattgggaa gaatggagtt ccatagattc attggtacct atagtagtag 23520 atttaccttc aaaaaagcaa aatcggctat tgcagtcttg tataactaaa catgtggatc 23580 gacttttgga cctttgtaaa agaaacttgt caacgttcac aatcgatata tcttcttcat 23640 ggcgacaaaa tattattgaa aataatgaac agaaagaatt cgagtgcacc agtacagcaa 23700 ttacaggttg tctactaaat tatggtgcta catacaatta tgatcacact ttatttaaag 23760 ataacggcct ttcgtgtgaa acacttaaac tatacactct tgaagttcat tcaaaaaaaa 23820 aagatgtcag tgatactctc atacaattct c 23851 //