ID SPBC17G9 standard; DNA; FUN; 32618 BP. XX AC AL109846; XX SV AL109846.1 XX DT 16-AUG-1999 (Rel. 60, Created) DT 16-AUG-1999 (Rel. 60, Last updated, Version 1) XX DE S.pombe chromosome II cosmid c17G9. XX KW 40s ribosomal protein s24b; 60s ribosomal protein L11; biotin lipoyl; KW biotin-requiring; carboxylase; csx2; elongation factor Tu family; GTP EFTU; KW GTPase activating; helicases conserved c-terminal domain; KW lysyl-trna synthetase; nucleoporin; peptidyl prolyl cis-trans isomerase; KW PH domain; pre-mrna splicing factor atp-dependent rna helicase; KW RNA recognition motif; RNP domain; translation initiation factor. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-32618 RA Wood V., Rajandream M.A., Barrell B.G., Volckaert G.; RT ; RL Submitted (13-AUG-1999) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and Katholieke Universiteit Leuven, Laboratory of RL Gene Technology, Kardinaal Mercierlaan, 92 blok F, B-3001 Leuven, Belgium. XX DR GOA; O59865; O59865. DR GOA; Q09130; Q09130. DR GOA; Q10157; Q10157. DR GOA; Q9UUE1; Q9UUE1. DR GOA; Q9UUE2; Q9UUE2. DR GOA; Q9UUE4; Q9UUE4. DR GOA; Q9UUE5; Q9UUE5. DR GOA; Q9UUE6; Q9UUE6. DR GOA; Q9UUE8; Q9UUE8. DR SPTREMBL; Q9UUD9; Q9UUD9. DR SPTREMBL; Q9UUE0; Q9UUE0. DR SPTREMBL; Q9UUE1; Q9UUE1. DR SPTREMBL; Q9UUE3; Q9UUE3. DR SPTREMBL; Q9UUE4; Q9UUE4. DR SPTREMBL; Q9UUE5; Q9UUE5. DR SPTREMBL; Q9UUE6; Q9UUE6. DR SPTREMBL; Q9UUE7; Q9UUE7. DR SPTREMBL; Q9UUE8; Q9UUE8. DR SWISS-PROT; O59865; R24B_SCHPO. DR SWISS-PROT; Q09130; IF2G_SCHPO. DR SWISS-PROT; Q10157; RL11_SCHPO. DR SWISS-PROT; Q9UUE2; CSX2_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 80% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c17G9 no overlaps found sofar. XX FH Key Location/Qualifiers FH FT source 1..32618 FT /chromosome="II" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c17G9" FT /map="IIR" FT misc_feature complement(1..2203) FT /note="nominal overlap with Cosmid c1711 S. pombe FT chromosome 2; " FT CDS 1..2988 FT /codon_start=1 FT /db_xref="GOA:Q9UUE8" FT /db_xref="SPTREMBL:Q9UUE8" FT /label=SPBC17G9.01 FT /note="SPBC17G9.01, len:995, SIMILARITY:Homo sapiens, FT PR16_HUMAN, pre-mrna splicing factor atp-dependent rna FT helicase prp16, (1227 aa), fasta scores: opt: 3373, E():0, FT (52.3% identity in 1013 aa)" FT /partial FT /gene="SPBC17G9.01" FT /product="putative pre-mrna splicing factor atp-dependent FT rna helicase" FT /protein_id="CAB52799.1" FT /translation="DHQEFESEDDKYRRNSYSSWSGSNFESSNGSNRRRYRTQMEEPLS FT SKRRNRFGNGSRRDVDSSKYSHDSDYSYGAHSSWDARDVEYPEEDPESKADRQRWEEEQ FT AHLDRDWYMNSESQNLLGDEVHNPFSDFETVEDRAHEAEFIEKQKKHLSIEASDRFKEN FT SMWEKNRMITSGVSKAPGLESDYSLMEERRVHLLVDELRPHFLDGAEFSSKKVGDITSV FT RDPQSDLAINARLGSRLVRERREFRERQKAASAATSLAGTSLGNVMGLKDSNDEDAKAG FT TTPVKVAGRSEQSNKKDTEFARTKSYREQREFLPAFAVREQLLSVIRDNQVLIVVGETG FT SGKTTQLAQFLYEDGYHRNGMIGCTQPRRVAAMSVAKRVSEEMGVRLGSTVGYSIRFED FT VTGPDTVIKYMTDGVLLRESLMQNNLEKYSVIIMDEAHERSLNTDILMGLLKKVLSRRR FT DIKLLVTSATMNSQKFSDFFGGAPQFTIPGRTYPVDIMFAKAPCSDYVEAAVRQVLQIH FT LSQPAGDILVFMTGQEDIEATCEIIADRLNQLHDAPRLSILPIYSQMPADLQAKIFDSA FT EPGVRKVVVATNIAETSLTVHGISYVVDTGYCKLKMYNSKLGIDTLQVTPISQANANQR FT AGRAGRTGPGIAYRLYTEMAYIREMFETTLPEIQRTNLSNTVLILKSLGVEEISDFDFM FT DRPPNDTLMASLYELWTLGALDNFGKLTTLGKKMSLFPMDPSLSKLIIIAEDYKCTEEI FT ITIVSMLSVPSVFYRPKERAEESDAAREKFNVPESDHLMLLNIYQHWQRNGYSNSWCSK FT HFLHSKTLKRARDIRQQLVEIMSKQKISLESVSDWDIVRRVLCSAYFHQAACAKGIGEY FT VHLRSGMPCHLHVTSSLYGLGYLPDYVIYHELVLTSKEYMNIVTSVDPYWLAEFGGVYY FT SVKERFRNETESYDRVFSSKPQLDAQIAADRELDAKQKLAKNQEPVKSKRKSVIRAKPP FT RRVRGF" FT misc_feature 1009..1032 FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature 1618..1923 FT /note="Match to PF00271 helicase_C, Helicases conserved FT C-terminal domain Score 27.97" FT CDS join(complement(4111..4468),complement(3902..4047), FT complement(3749..3851),complement(3199..3707)) FT /db_xref="SPTREMBL:Q9UUE7" FT /label=SPBC17G9.02c FT /note="SPBC17G9.02c, len:371, SIMILARITY:Candida albicans, FT O94026, hypothetical 42.5 kd protein., (370 aa), fasta FT scores: opt: 640, E():0, (32.2% identity in 366 aa)" FT /gene="SPBC17G9.02c" FT /product="hypothetical protein" FT /protein_id="CAB52800.1" FT /translation="MDSLLLLKKSIAEKKDVKLLASSEATSKVEKIEDAQYILFDENTS FT PILIDEPTKFIKLENDSHFSLRSVYFAWLLRDTSIAEYIQQCSELGIQNLTFLERTDLI FT SWLEGSSDSEHIIGLEKPKPEGSTDAATSMDVDLHKKSEEVNWLFENTRTVSNHNSVLH FT GIKPIDFISLRKDVLDYIHANKATASAHADEQERPAKKRNRDPIILLSPSASSLLTMHN FT IKKFLEEGIFVPPAEAAHAAGGGRGPELIALSHKSSNSKFGTMRFIIVEGTEKFKPDYW FT DRVVCVFTTGQAWQFRDYKWSEPHQLFHHVKGFLVQYVGDPPHPATHDWNVEGIFVERL FT RRHTDREVVSQLWDKLERWMENRWPLWNGRR" FT misc_feature complement(3708..3722) FT /note="ctaatcaatttttag, splice branch and acceptor" FT misc_feature complement(3743..3748) FT /note="gtgtgt, splice donor sequence" FT misc_feature complement(3852..3865) FT /note="ctaactttttttag, splice branch and acceptor" FT misc_feature complement(3896..3901) FT /note="gtatgt, splice donor sequence" FT misc_feature complement(4048..4067) FT /note="ctaacattgtttatgagtag, splice branch and acceptor" FT misc_feature complement(4105..4110) FT /note="gtatgc, splice donor sequence" FT CDS complement(5065..6840) FT /db_xref="GOA:Q9UUE6" FT /db_xref="SPTREMBL:Q9UUE6" FT /label=SPBC17G9.03c FT /note="SPBC17G9.03c, len:591, SIMILARITY:Saccharomyces FT cerevisiae, SYKC_YEAST, lysyl-trna synthetase, cytoplasmic, FT (590 aa), fasta scores: opt: 2601, E():0, (65.0% identity FT in 586 aa)" FT /gene="SPBC17G9.03c" FT /product="putative lysyl-trna synthetase" FT /protein_id="CAB52801.1" FT /translation="MSEEQVNGVTQAVKALVLDPVTGEQVSKTELKKREKQRARELAKA FT KKQAEKAASAPVAAPKSSSKKEEDLDPSQYFENRSRTIMELRQTKDPNPYPHKFQVTIT FT LPEFIAKYEGLARGETKPEVEVAVAGRVLGLRTAGNKLRFYEIHADGKKLQVMCQAQDA FT DTVDFAAQHEHLRRGDIIGIRGYPGRSNPKGRADGELSIFARQCVLLSPCLRMLPKEHY FT GLKDLEIRHRQRYLDLIMNRSTRDRFVMRSRIIQYIRHFFDSRDFMEVETPMMNMIAGG FT ATAKPFVTHHNDLDMDLYMRIAPELYLKMLVVGGLDRVYEIGRQFRNEGADLTHNPEFT FT SIEFYQAYADYYDLMDTTEELLSGLVKDLTGSYKVPYHPEGPEGPKWELDFSRPWRRIN FT MIEYLEEKLNTKFPPGDQLHTPEANAFLRDLCAKHGVECAPPQTCSRLLDKLVGEFIES FT ECINPTFIIGHPQMMSPLAKYHRSDAGLCERFEAFVATKEICNAYTELNDIFDQRARFE FT EQARQKAQGDDEAQIIDENFCTALEYGLPPTGGWGMGVDRLVMFLTDSNTIREVLLFPH FT MKPEVQAAEPTVVKE" FT misc_feature complement(5104..6165) FT /note="Match to PF00152 tRNA-synt_2, tRNA synthetases class FT II (D, K and N) Score 648.83" FT CDS complement(7309..9336) FT /db_xref="GOA:Q9UUE5" FT /db_xref="SPTREMBL:Q9UUE5" FT /label=SPBC17G9.04c FT /note="SPBC17G9.04c, len:675, SIMILARITY:Saccharomyces FT cerevisiae, NU85_YEAST, nucleoporin nup85, (744 aa), fasta FT scores: opt: 183, E():7.8e-05, (20.7% identity in 639 aa)" FT /gene="SPBC17G9.04c" FT /product="similarity to nucleoporin" FT /protein_id="CAB52802.1" FT /translation="MESSDEVDLPVYHLQNAPIENGKLNDWRSKGRTVAFKLHPFLRKG FT LAYINNKEFDENTLKSDKFEEVESLVYEFSTPSTLIEPNYLLTAWHELWEELQDTYMTP FT ILDSEANLLLLTQFYGKISSLFRSKIIQVLEELQSRINEGEKDCQPVLDSLWEVESAWR FT CAEAIYFPPSSPYTLSTGILDWVNAYDPQPIADDGLEIMAYRIPYQHPEFWPYVNKTAI FT RGLFEQTISCLEMSGLTKEWPVLKETVDELIDILRYSPCTHQKRIRSVSDFERRWKLWR FT SRLANLRHVVKKHRDIDSEVLDDFVVLLDILNGNKEVIMLSCAHWQEYFSALAFLYGPL FT DCKNPEDISLLYQLATGEDSKFYVNGTIEYEQICVNLCSNEPLNAIKHAYLLDLGLAVH FT LADLLSKSGHLRDYITEEYPITLREHLILEYGQCVLESRNLWQTSFAYWKCVADSGYQR FT IKACIPYVPLSDVDAKETALQLCKQLKLRDEAQLVLTHWADELIARNHYGEALIALDNA FT ANYSALNRVTWELFDICIAEKKSFSPDKDELLYELFSSPKACTPTLASIISPAATIHQY FT FFYLQHKKELNASELLVGLLTMVDFPSSRFPKLLELLHEFLNNPLQSNSTDFKLSLVNV FT YDCIAVLQDQQSTVKDQQLLLSIHERLSSAISWYFLHLKK" FT CDS 11242..12540 FT /db_xref="GOA:Q9UUE4" FT /db_xref="SPTREMBL:Q9UUE4" FT /label=SPBC17G9.05 FT /note="SPBC17G9.05, len:432, SIMILARITY:Drosophila FT melanogaster, AAD34736, hypothetical 75.5 kd protein., (653 FT aa), fasta scores: opt: 1226, E():0, (46.0% identity in 459 FT aa)" FT /gene="SPBC17G9.05" FT /product="putative peptidyl prolyl cis-trans isomerase with FT RNA binding region" FT /protein_id="CAB52803.1" FT /translation="MSVLIETTVGDLVIDLFVKEAPKTCENFLKLCKLKYYNFCPFYNI FT QHNYTCQTGDPLGPTGDGGRCVWNVLNKGTRFFKAEFNPSLVHNKMGLVSMSTATISSR FT DDKLLVCGSQFIITLSDNLEGLDERYPIYGQVAEGFDTLLKINDAICDEEGQPYRDIRI FT KHTIILDDPFEDPPDLVEPLRSPSPTPEQLATVRIGENEQIESETSEDKLQREKEMEAE FT AEAVTLEMIGDLPFAHVAPPENVLFVCKLNPVTQDEDLELIFSRFGKIISCQVIRDKET FT GDSLQYAFIEFDNKESVEKAYFKMQNVLIDDSRIHVDFSQSVARYRQYYNSNRDRKRSS FT SRSDDREYHRRSDGRYDRSNYRDDYRHRRKERDHRDDQSSFRNERFSNYYGDDRSYHKR FT RNTGNKNCDDHLRDKSPERRYRYDRRYRDDRYR" FT misc_feature 11248..11340 FT /note="Match to PF00160 pro_isomerase, Peptidyl-prolyl FT cis-trans isomerase Score 33.35" FT misc_feature 11977..12192 FT /note="Match to PF00076 rrm, RNA recognition motif. (a.k.a. FT RRM, RBD, or RNP domain) Score 74.99" FT CDS complement(12696..13700) FT /db_xref="SPTREMBL:Q9UUE3" FT /label=SPBC17G9.06c FT /note="SPBC17G9.06c, len:334, SIMILARITY:Escherichia coli., FT Q47317, plasmid iuca, iucb and iucc genes., (315 aa), fasta FT scores: opt: 645, E():0, (37.5% identity in 275 aa)" FT /gene="SPBC17G9.06c" FT /product="hypothetical protein" FT /protein_id="CAB52804.1" FT /translation="MSFTVWSKTEPFKLSAVQESLITLEHDNKRLLLTYREESKTWDID FT LNGFQDMDVNEILQLAFLSIFYVFPTLRTEVVLQWANIESQKGTLSLPVEYNELEGNVS FT IDRMSFWQIPSPWMYTRCSDWPLSYLPNQVIRRPKCPKPGSTLYERFIPSLNETLSFVS FT LDIEQHLQYFHEWQNKPRVEYFWNESGSWDQHHEYLTTLQNDPHSFGVIGCFNDVPFAY FT FEVYWVPEDRIAPFAQPWHTHDRGFHALVGNDKFRGPHRVPVWLSSITHMLFLDDPRTQ FT RVLLEPRIDNSKFINYLIEENYSKRLEFNFPHKRAAFMEITRNMFFSCLGPRI" FT CDS join(14139..14207,14289..14624) FT /db_xref="GOA:O59865" FT /db_xref="SWISS-PROT:O59865" FT /label=rps24-2 FT /note="SPBC17G9.07, len:134" FT /gene="rps24-2" FT /gene="rps24a" FT /gene="SPBC17G9.07" FT /product="40s ribosomal protein s24b" FT /protein_id="CAB52805.1" FT /translation="MSEAVTIRTRKFMTNRLLQRKQMVVDILHPGKANLSKNEIREKLA FT QMYKTDSECVQAFGLRTHFGGGRSTGFALIYDSTESMKKFEPHYRLVRVGQAEPIQKVA FT RQQRKQRKNRGKKVFGTGKRLAKRKSKQQD" FT misc_feature 14208..14213 FT /note="gtatgt, splice donor sequence" FT intron 14208..14288 FT /note="confirmed intron" FT misc_feature 14272..14288 FT /note="ctaacggaaatttatag, splice branch and acceptor" FT misc_feature 14289..14537 FT /note="Match to PF01282 Ribosomal_S24e, Ribosomal protein FT S24e Score 130.59" FT CDS join(complement(17848..17884),complement(17658..17791), FT complement(17431..17613),complement(17163..17306), FT complement(15485..17111),complement(14953..15440)) FT /db_xref="GOA:Q9UUE2" FT /db_xref="SWISS-PROT:Q9UUE2" FT /label=csx2 FT /note="SPBC17G9.08c, len:870" FT /gene="csx2" FT /gene="SPBC17G9.08c" FT /product="csx2 protein" FT /protein_id="CAB52806.1" FT /translation="MTGHVDPVHFERLKIQSVTFGSANDNASLQVHNVSKSPEYSKYSY FT SRKNNEPIEFIQLREEEGPIVKVEEEDGLTLRFQLEFHAQEGKRDVTNLTCVYGTSPQQ FT LDRLITREFSSDANFQNNHQVFLIGNIEFHSNENSKKIEWTWSNQSLHTLYFRNGGSPI FT YLCFAEYDKRLNCLVPLKTFQFYVTESDQDSTPATPFPMPMHLAEETATSPEISDAPPL FT SGNVDPLPINSPPLTNPVARDIDQTEPEDGPLFRATILNYERTTHDMRMVLKKLIKRIE FT HVAHSHGLLYMSYKELMSAFERVATINPPAFKPFLDHYYAAAAQSFDSFNIDRARLLRN FT FLIEPLRKIYDTDIKNVSTKKKDFEETSRDYYTSLSRYLSKSEKETSSDKTKESKFAAK FT KRDFELSRFDYYSYMQDINGGRKGQEVLSVLTSFAANDYNLIHSSLTDIDALRPSIIQL FT QDIVTEANKEFQLLRAEREERRRYIETSSRELEDKDAEIAAQAYKAKVDQDTSAKQGLL FT LAFSKSTSDLQVVGKSGWHKYWVVLDHGKICEYANWKQSLELHTEPIDLLMATVRPAQS FT VSRKFCFEVITPQTKRTYQATSKAEMHSWIEAIQYSISESIVQKGKGTSMNSEETSVKH FT GPTSTIGKALQRVASVTSPSRHNSDSKEKKQTKSPSLVKTLKEMHSSDQSCADCNTTAR FT VEWCAINFPVVLCIDCSGIHRSLGTHITKIRSLTLDKFNPETVDLLYATGNSFVNEIYE FT GGITDWKIKNFENQERRVQFVKDKYLYKRFIKSSFSHDPNTGLLESIEHSNLKEAVLCL FT ALGADVNYQRAVVKALLKNNYLIAELLTLNGASLNVDEVTMETLSARAQAFVMNRATP" FT misc_feature join(complement(15485..15584),complement(15211..15440)) FT /note="Match to PF01412 ArfGap, Putative GTP-ase activating FT protein for Arf Score 123.46" FT misc_feature complement(15441..15453) FT /note="ctaacaagaacag, splice branch and acceptor" FT misc_feature complement(15479..15484) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(15771..16031) FT /note="Match to PF00169 PH, PH domain Score 33.01" FT misc_feature complement(17112..17123) FT /note="ctaaatatgcag, splice branch and acceptor" FT misc_feature complement(17157..17162) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(17307..17322) FT /note="ctaacttttgattcag, splice branch and acceptor" FT misc_feature complement(17425..17430) FT /note="gtatgt, splice donor sequence" FT misc_feature complement(17614..17628) FT /note="ctaacacatcttcag, splice branch and acceptor" FT misc_feature complement(17652..17657) FT /note="gtatga, splice donor sequence" FT misc_feature complement(17792..17806) FT /note="ctaactctgctaaag, splice branch and acceptor" FT misc_feature complement(17842..17847) FT /note="gtatgt, splice donor sequence" FT CDS 20920..22260 FT /db_xref="GOA:Q09130" FT /db_xref="SWISS-PROT:Q09130" FT /label=tif213 FT /note="SPBC17G9.09, len:446" FT /gene="tif213" FT /gene="SPBC17G9.09" FT /product="eukaryotic translation initiation factor 2 gamma FT subunit" FT /protein_id="CAB52807.1" FT /translation="MAENLDISELSPIHPAIISRQATINIGTIGHVAHGKSTVVKAISG FT VHTVRFKNELERNITIKLGYANAKIYKCSNEECPRPGCYRSYSSNKEDHPPCEICNSPM FT NLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMQLK FT HIIILQNKVDLIRESAAEEHYQSILKFIKGTVAENSPIVPISAQLKYNIDAILEYIVKK FT IPIPVRDFTTAPRLIVIRSFDVNKPGAEVDDLKGGVAGGSILTGVLRLNDEIEIRPGIV FT TKDDDGRIRCQPIFSRIISLFAEHNDLKIAVPGGLIGVGTTVDPTLCRADRLVGQVLGS FT KGNLPEVYTELEINYFLLRRLLGVKSGDKNTTKVQKLAKNEVLMVNIGSTSTGGRVMMV FT KADMAKILLTAPACTEIGEKVALSRRIEKHWRLIGWAKVVEGKTLKV" FT misc_feature 20986..22176 FT /note="Match to PF00009 GTP_EFTU, Elongation factor Tu FT family Score 172.41" FT CDS 22933..23457 FT /db_xref="GOA:Q10157" FT /db_xref="SWISS-PROT:Q10157" FT /label=rpl11 FT /note="SPBC17G9.10, len:174" FT /gene="rpl11-2" FT /gene="SPBC17G9.10" FT /product="60s ribosomal protein L11" FT /protein_id="CAB52808.1" FT /translation="MAEKAQNPMKELRISKLVLNISLGESGDRLTRAAKVLEQLSGQTP FT VFSKARYTIRRFGIRRNEKIACHVTVRGPKAEEILERGLKVKEYELKKRNFSATGNFGF FT GIQEHIDLGIKYDPSIGIYGMDFYVVMDRPGMRVARRKAQRGRVGYTHKINAEDTINWF FT KQKYDAVVLGK" FT misc_feature 22951..23112 FT /note="Match to PF00281 Ribosomal_L5, Ribosomal protein L5 FT Score 90.75" FT misc_feature 23122..23421 FT /note="Match to PF00673 Ribosomal_L5_C, ribosomal L5P FT family C-terminus Score 218.76" FT CDS complement(24082..27639) FT /db_xref="GOA:Q9UUE1" FT /db_xref="SPTREMBL:Q9UUE1" FT /label=pyr1 FT /note="SPBC17G9.11c, len:1185, SIMILARITY:Aspergillus FT terreus., O93918, pyruvate carboxylase., (1193 aa), fasta FT scores: opt: 5531, E():0, (68.5% identity in 1173 aa)" FT /gene="pyr1" FT /gene="SPBC17G9.11c" FT /product="pyruvate carboxylase (EC 6.4.1.1)" FT /protein_id="CAB52809.1" FT /translation="MTSKYDALLHNQSTNTNPFSKLQDRSSLLGEKFTKVLVANRSEIA FT IRVFRTAHELSMHTVAIYSYEDRLSMHRQKADESYPIGKVGQYSPVGAYLAIDEIVSIA FT KRTGANLVHPGYGFLSENAEFARKVNEAGMQFVGPSPEVIDSLGDKTKARAIAIRCGVP FT VVPGTPGPVEHYEEAEAFVKEYGLPVIIKAAMGGGGRGMRVVRSADTLKESFERARSEA FT LASFGDGTVFIERFLDKPKHIEIQLMADKAGNVIHLHERDCSVQRRHQKVVEIAPAKDL FT DPKIRQALYDDAIKIAKEVKYCNAGTAEFLLDQKGRHYFIEINPRIQVEHTITEEITGV FT DIVSAQLHVAAGFTLPEIGLTQDKISTRGFAIQCRVTTEDPNNGFAPDIGKIEVYRSAG FT GNGVRLDGANGFAGSVITPHYDSMLVKCTCHDATYEYTRRKMIRSLIEFRVRGVKTNIP FT FVLRLLMHDTFIQGNCWTTFIDDTPELFQLYRSRNRAQKLLAYLGDLAVNGSSIKGQNG FT EPALKSEIVMPVLLDSTGNQIDVSHPSEKGWRKLLLDNGPAAFAKAVRNHKRGLIMDTT FT WRDAHQSLLATRVRTIDLVNIAPYTSHALASAYSLEMWGGATFDVSMRFLHECPWDRLR FT RLRKLVPNIPFQMLLRGANGLCYSSLPDNVIYFFCEQAKKNGIDIFRVFDALNDVNNLS FT LGIDAAKRAGGVVEATMCYSGDMLNPKKKYNLDYYVNLVDKMVEMGIHILGIKDMAGVM FT KPKAARLLISAIREKHPELPIHVHTHDSAGTAVASMAAALEAGADVVDVATDSMSGLTS FT QPSFGAVLASVDGTDKQLEFDNNQLREIDSYWAQMRLLYSPFESEIKGTDSDVYNHEIP FT GGQLTNLKFQATSLGLGTQWAETKKAYIEANKLLGDIIKVTPTSKVVGDLAQFMVQNKL FT SAEDVENRATTLDFPASVLDFFQGLMGQPYGGFPEPLRTNVLKGRRQPLTDRPGKFLPA FT ADFDAIRKLLSEKFGVSSDCDIAAYTQFPGVFEEYRQFVDRYGDLTTVPTKFFLSRPEM FT NEEMHVEIDQGKTLIVKFVALGPLNPRTGQREVYFELNGENRHVTVEDKKAAIETVTRP FT RADPGNPGHVAAPMSGTIVEIRVKEGAKVKKGDIIAVLSAMKMEIVISAPHSGVLKSLA FT VVQGDSVNGGDLCAVLEHE" FT misc_feature complement(24094..24291) FT /note="Match to PF00364 biotin_lipoyl, Biotin-requiring FT enzymes Score 86.03" FT misc_feature complement(25060..25839) FT /note="Match to PF00682 HMGL-like, HMGL-like Score 222.60" FT misc_feature complement(26200..27537) FT /note="Match to PF00289 CPSase_L_chain, Carbamoyl-phosphate FT synthase (CPSase) Score 666.34" FT CDS complement(28408..29232) FT /db_xref="SPTREMBL:Q9UUE0" FT /label=SPBC17G9.12c FT /note="SPBC17G9.12c, len:274, LOW SIMILARITY:Archaeoglobus FT fulgidus., O28142, phosphoserine phosphatase, (344 aa), FT fasta scores: opt: 113, E():0.86, (22.1% identity in 253 FT aa)" FT /gene="SPBC17G9.12c" FT /product="hypothetical protein" FT /protein_id="CAB52810.1" FT /translation="MLYIVDFDETITTYDTIHLLAEAVNKPEEWSVISDKYWQEYLAWR FT EALPHSTTLTSYLPLLGGSRYLEEASIKRIEKSQYFSGLSEGALDNIVQLITLRAGFVE FT FINALVPDLRVSKTIFHVLSVNWSARVIEQTLLHHTDLTADLLCVHANDFDFDTSTNTT FT NGRILARNASSLLMNSTDKVREFRRIVQTDAVSSPLNVVYIGDSPTDFGCLQISPISIL FT MRSNQKYYDILSRFEDVQLVDISEFPVQKAVPGKKIIYTCSDWCAIQKAFLA" FT CDS complement(29792..30745) FT /db_xref="SPTREMBL:Q9UUD9" FT /label=SPBC17G9.13c FT /note="SPBC17G9.13c, len:317" FT /gene="SPBC17G9.13c" FT /product="hypothetical protein" FT /protein_id="CAB52811.1" FT /translation="MRFISTVTKRRPFQAPNDLVHPLSNILGSLVTYDSRLHLPQPKDR FT QCSTLVPLYRRLLKATRRFWDPMASQILISHFQAYARKARKSNPNPHKRRIKRFRNLLK FT TFACRIERANDGDHQAIWQTLRYAYSQTGPLRHRRLHYLQDNKIRPSKIPKSLPSNSPV FT RLPYISSLLSAVFEINMENAKIRHLPSVIFDGLIEKNKDRPYHINLSCKRAYDELLPRI FT AVPLLPHEYHHLHSLLLDVTLRNPQISRPPFAPLNPRKGFCRILQRSLITFLSAVCYLP FT YNPHPTSKPVVSWDSLSDIQLRLNVGKVLKKSVKKR" FT misc_feature 32379..32618 FT /note="nominal overlap with c1815 S. pombe chromosome 2" XX SQ Sequence 32618 BP; 10633 A; 5931 C; 6407 G; 9647 T; 0 other; gatcatcaag agtttgaaag tgaagatgat aaatatcgta gaaattctta ttctagctgg 60 tctggaagta atttcgagtc ttccaatgga tctaatcgtc ggcggtatcg aactcaaatg 120 gaagaacctt tatcctcaaa acgcagaaat cggtttggta atggttctcg aagagacgtc 180 gatagctcta aatattcgca cgatagtgat tattcttatg gtgcacacag ctcttgggat 240 gcccgcgacg ttgagtaccc cgaagaagat cccgagagta aagctgatcg tcaacgttgg 300 gaagaggagc aagctcactt ggatcgtgat tggtacatga attccgagtc gcaaaattta 360 cttggcgatg aagttcacaa tccattctcc gattttgaaa ctgtcgaaga tcgtgcacat 420 gaagctgagt ttatcgaaaa gcagaaaaag catttgtcaa ttgaagcatc agacagattt 480 aaagaaaatt ctatgtggga aaaaaataga atgatcacat ctggtgtttc aaaagctcca 540 gggctcgaat ctgattactc ccttatggaa gagaggcgtg ttcacttgct tgtcgatgaa 600 ctgcgtcctc attttttgga tggggccgaa ttttcttcta agaaagtcgg tgatattaca 660 tcggttcgag atccacaaag cgaccttgca ataaatgcta gattaggatc tcgtcttgta 720 cgtgaacgaa gagaatttcg ggagcgtcaa aaagcagcaa gtgctgctac atcccttgct 780 ggtacatctt tgggtaacgt gatgggtctc aaagattcta atgatgaaga tgccaaggcc 840 ggtaccacac ctgttaaagt agctggacgt tctgaacagt cgaataagaa ggatactgag 900 ttcgctcgca cgaaatcata tagagaacaa agagagttcc tacctgcctt tgccgtgcgt 960 gaacagcttc tttctgttat acgtgataac caagttctta ttgtagttgg tgagactggt 1020 tctggtaaaa ctacccaatt agctcaattc ttatatgagg atggctatca tagaaatggc 1080 atgatagggt gtactcaacc tcgtcgtgtc gccgccatgt cagttgcaaa aagggttagt 1140 gaggaaatgg gtgttcgtct aggttcaaca gttggttatt caattcgttt cgaagatgtt 1200 actggaccgg ataccgtaat taagtacatg actgacggtg ttttactaag agaatccttg 1260 atgcaaaata atctagaaaa atatagcgtc attataatgg atgaagcaca tgagcgatcc 1320 cttaatacag atattttaat gggtttacta aaaaaggtgt tatccaggag aagagatatc 1380 aagttgctcg ttacatccgc tactatgaat tcccagaaat tctctgattt ttttggaggc 1440 gccccacagt ttacaattcc aggtcgtact tacccggtgg atattatgtt tgctaaagcc 1500 ccttgctctg attacgttga agcagctgta cgacaggtat tgcagattca cctctctcag 1560 cctgcaggtg atatcttagt ttttatgaca gggcaggaag atattgaagc tacatgcgag 1620 atcattgcag ataggttaaa tcagttgcat gatgcaccac gcttgtccat tttgcctatc 1680 tactcacaaa tgcctgcgga tttacaagca aaaatttttg attccgccga gccaggtgtt 1740 agaaaggttg tggtcgcaac taatattgcg gaaacttcgc tcactgtgca cggaatatca 1800 tatgttgtag atactggata ttgtaaactg aaaatgtata attctaagtt gggtattgat 1860 actctgcaag ttacacctat ttcgcaagct aatgcgaatc aaagagccgg tcgtgctggg 1920 cgtactggac ccggtattgc atatcgcctt tataccgaaa tggcttatat tcgtgaaatg 1980 tttgaaacga ccttacctga aattcagcgt accaatctat caaacacagt tcttatttta 2040 aaatcccttg gtgttgaaga aatttcggat tttgatttca tggaccgtcc tccaaatgat 2100 acgttaatgg catctctgta tgaattatgg actttaggag ccctcgacaa ttttggaaaa 2160 cttactactt taggaaagaa aatgtcgtta tttccaatgg atccttctct ttcaaaactt 2220 attattattg ctgaagatta taaatgtact gaggaaatta ttacgattgt ttccatgctt 2280 tcagttccgt ctgtatttta tagacccaag gaaagagctg aagagagtga cgctgcaaga 2340 gaaaagttta atgtgccaga aagtgatcat ttaatgctac tcaatattta tcagcattgg 2400 caaagaaatg gatattcaaa ttcatggtgc agtaaacatt ttttacactc gaaaactctt 2460 aaacgggcgc gcgatattcg tcaacagctg gtcgaaatta tgtcaaagca aaagattagt 2520 ttagaatctg tatccgattg ggacattgtt cggagagttt tgtgttctgc gtactttcat 2580 caagcagcat gcgctaaagg tattggggag tatgttcatt tacgaagcgg catgccttgc 2640 catctacatg ttacttcgag tctttatggc ttagggtatc tacctgatta tgttatatat 2700 cacgaacttg tactcacttc caaggagtac atgaatattg tcaccagtgt tgatccatac 2760 tggctagctg agtttggtgg agtttactac tctgtgaagg aaagattccg aaatgaaact 2820 gaaagctatg atcgagtttt ttctagcaaa cctcaattgg atgcacagat agccgccgac 2880 cgagaacttg atgcaaagca aaagcttgcg aagaatcaag aacccgtgaa atcaaaacga 2940 aagtcagtga tacgtgccaa acctcctaga agggttcgtg gattttaatg agaactctgc 3000 aaaaaggttc ccatctcaaa attctatgta aattatgtta tgaataatgt gctaggttta 3060 tggtaataaa gaaattcagt tattaacatt tttttattat tttaaattga gaggattaat 3120 aaattcatta agaaagtgaa aaatagtttt ttagcagtaa ttataaagaa cgggatttga 3180 aaacatttat atacataatt accttctgcc gttccaaagc ggccatctat tttccatcca 3240 gcgttctaac ttatcccaca attgactgac tacttcacga tcagtatgtc gtcgtaatct 3300 ttccacaaaa atgccttcta cattccagtc atgtgttgca ggatgaggag gatcaccaac 3360 gtattgaacc aaaaatcctt taacatgatg aaaaagctgg tgcggttctg accatttata 3420 atctctaaac tgccaagctt ggcctgttgt aaaaacgcaa acgacgcgat cccaatagtc 3480 aggtttaaac ttttctgtac cttctacgat aataaaacgc attgttccaa attttgaatt 3540 cgagcttttg tgggacagag caataagctc aggaccacga ccaccaccag ctgcatgagc 3600 ggcttcagct ggaggaacaa aaataccttc ttccaaaaat ttcttaatat tgtgcattgt 3660 caataaagac gaagcggaag gtgaaagcag aataatagga tcccgatcta aaaattgatt 3720 agttctaggc ataataaaaa aaacacactt ctttttttag ccggtctctc ttgctcatcg 3780 gcgtgagcgc tagcagtagc cttgtttgca tgaatatagt caagaacatc ttttctcaag 3840 gaaataaaat cctaaaaaaa gttaggattt tgagactttt gttaaataaa tcgcaacata 3900 caattggctt aataccatgc aacacagagt tatgattgga aacggttcgg gtattctcaa 3960 ataaccaatt aacctcttca cttttcttat gcaaatcaac atccattgaa gtagctgcgt 4020 cagttgaccc ttcaggttta ggcttttcta ctcataaaca atgttagctt tgccaaattt 4080 tttaaagaaa gaagttttta taacgcatac ccaagccaat gatatgttca ctgtccgaag 4140 aaccctctaa ccaagaaatt aagtctgttc tttccaaaaa agttaaattt tgaataccca 4200 actcggaaca ttgttgaatg tactcagcaa tgctcgtgtc tcgcaacagc caagcaaagt 4260 aaacacttcg taaagaaaaa tgactgtcat tttccaattt aataaatttt gtgggttcgt 4320 ctattaatat tggagatgta ttttcatcaa acaggatata ctgcgcatct tctatttttt 4380 caaccttaga cgttgcttca ctactagcaa gtaattttac atcttttttc tctgcaatag 4440 actttttaag aagcaacaaa gagtccatct cctttgtttt gttgatactt aatcaagtag 4500 gtaaatggca cgcgtcggtc ggaccatgag gcatttactc gagtctctca gaagattgaa 4560 atcgtttgga tgaaggcatg acgagaccta aattgcaaag aattttactt tatgtttctt 4620 tattaattta atagttttca gtcgacgttt gggacaataa ggtgtttagt gataaatcta 4680 atcactatta gcacttgcag gacgattaaa tcaatttcaa atttatcgtt tatttgcttg 4740 aagatacgcc ttacacctct gaagtacata tacactcttt gctgccatat agaactactt 4800 atagcgaatg cacaccccga taaacttttt acgaccgact caaacagaat atttgaaagc 4860 tacccactaa actactctaa ccgaattgat ttaaaaagct accaagtttc tagtaactct 4920 cagtaaataa aaacattcat acagaagttc ccatgcaagt aatgtatcaa tatatattgg 4980 aaataagcat taggctgatt tcaatattta caaaaaaagg aaagatttga tcgacaaacc 5040 gaaatccgca aacacaaaaa tattttactc tttaacgaca gtaggttctg cagcttgcac 5100 ttcgggcttc atatgaggaa aaagcaagac ttcacggata gtgttactgt cagtcaaaaa 5160 cataacaaga cggtcaacac ccattcccca accaccggta ggaggtagac catactcaag 5220 ggccgtgcag aagttctcat caatgatttg agcttcatca tcaccctgag ccttttgacg 5280 agcttgttct tcgaaacgag ctcgttggtc aaaaatatcg ttcaactcag tataagcatt 5340 gcagatttcc ttagttgcaa cgaaagcttc aaagcgttca cacaggcccg catcagaacg 5400 atggtattta gccaatggag acatcatttg aggatgacca ataatgaaag taggattgat 5460 acattcactt tcaatgaact cgccaaccaa tttgtccaag agtcgggagc acgtttgagg 5520 tggggcgcat tcaacaccgt gcttagcaca caagtctctt aaaaatgcat tggcttcagg 5580 agtatgcaat tggtcaccag gtgggaattt agtgttaagt ttctcctcca aatactcaat 5640 catgttaata cgacgccaag gacgactaaa atcaagttcc cacttagggc cttcaggtcc 5700 ttcaggatgg tagggaactt tgtaggaacc ggtaaggtct ttcacaagac cagaaagtag 5760 ctcttcagtt gtgtccatga gatcatagta atcagcatag gcttgataaa attcaataga 5820 tgtgaattct gggttatggg tcaagtcggc accttcgtta cgaaattgac ggccaatttc 5880 gtaaacccga tccaaaccac ctacaacaag cattttaaga tacagttcgg gagcgatacg 5940 catgtacaaa tccatatcta aatcattatg atgagtaaca aaaggtttgg cagtagcacc 6000 accagcaatc atgttcatca taggagtctc cacctccata aagtcacggc tatcgaaaaa 6060 gtgacggatg tattgaatga tacggctacg cataacaaaa cggtcacgag ttgagcgatt 6120 cataataagg tctaaataac gttggcggtg acgaatttct aaatccttca aaccataatg 6180 ttctttagga agcatgcgta aacaaggact aagtaaaacg cattgacgag caaagattga 6240 aagttcacca tcagcacgtc ccttagggtt ggaacgacca ggatatccgc gaataccgat 6300 aatatcacca cgtcttaaat gctcatgctg agcagcaaag tcgacagtgt cagcatcttg 6360 cgcttgacac ataacttgaa gctttttccc atcagcatgg atttcataga aacgcagctt 6420 attaccagca gtacgaagcc caagaacacg gccggcaact gcaacttcaa cttcaggctt 6480 agtttcacca cgagctagtc cctcatattt ggctataaat tcagggaggg tgatggtgac 6540 ctggaacttg tggggataag gattaggatc cttcgtttgg cgtaattcca tgatagtacg 6600 agaacgattt tcaaagtact gggaagggtc caaatcttct tccttctttg aagagctctt 6660 aggagcagca acaggagcag acgcagcctt ttcggcttgc ttttttgctt tagctaattc 6720 acgagcacgt tgtttttcgc gcttctttaa ctcagtcttt gagacttgtt caccagtgac 6780 gggatcaagg actaaagcct ttacagcctg tgtaactcca ttcacctgtt cctcactcat 6840 tttagcttac aattgccgtt ttcaggtttc agagaaattt tcgtggagga agagaatatt 6900 taccccttgt agatggtagt tccgtaacat aagatagtgt aatataacac attccgttat 6960 ttagttaata tttttttaaa atgattctgt tgatatatgc taaacgtttg aagatgtgag 7020 taataaatgt gtaaaatttt ttagatttac aacatcggct gggttcactg attttggatc 7080 ctccctatta tggtattaga cgagacatta taatgggtct ttaagatgaa caattgtatc 7140 ttaataaaaa catgtatgaa gcttctatgt tacagaaaga ttaaaatgtc aagtaacaga 7200 aatagcctaa tttaaatccc caattgagta aataactcaa ttatgtacaa gtgagccaaa 7260 atttgcagaa aaaatatata gcatagctac tatagaatta aaccgttttt atttttttaa 7320 gtgaagaaaa taccatgata tcgcagaaga aagacgctca tgaatggata gtaaaagctg 7380 ctggtccttt acagttgact gttgatcctg taagacagcg atacaatcat aaacattaac 7440 aagagaaagc ttaaaatctg tcgagttaga ctgtaaagga ttattcaaaa attcgtgaag 7500 tagttctaat aacttaggga atcgacttga agggaaatca accattgtta gtaacccaac 7560 aagaagttca gaggcattga gctctttttt gtgctgaagg taaaaaaaat attgatgaat 7620 tgtagcagct ggagatatta tcgaggcaag ggtcggggta caggctttag gagagctaaa 7680 caattcatac aacagttcat ctttatcggg actaaatgac ttcttttctg caatacatat 7740 atcaaacaat tcccaagtaa cgcgatttaa agcagaatag ttcgcagcat tatctaaagc 7800 aattagtgct tcaccatagt gattacgtgc aattaattca tcagcccaat gagtcaatac 7860 taattgagct tcgtccctta gtttaagctg cttgcataat tgaagtgcag tttccttggc 7920 atccacatcg gaaagaggga catatggaat acaagctttt attcgttgat agccggaatc 7980 agcaacacat ttccagtaag caaaggacgt ttgccaaaga tttctacttt ctaaaacaca 8040 ctgcccatat tccagtataa gatgttcacg taaggtaatg ggatattcct cggttatgta 8100 atcccgcaaa tgaccgcttt tactcaataa gtctgctaaa tgcacggcta gtccaagatc 8160 tagaagatag gcgtgtttaa tagcgttaag aggttcatta ctgcataaat taacgcatat 8220 ttgttcatac tcaatcgttc cattaacgta aaactttgag tcttctccag ttgcaagttg 8280 atataataga gatatatctt caggattttt acaatccaaa ggaccatata aaaatgctaa 8340 agctgaaaaa tattcctgcc agtgtgcgca acttaacatg atgacttctt tatttccatt 8400 caaaatatca agcaaaacaa caaaatcatc caaaacttcc gaatcaatat cccgatgttt 8460 cttaaccaca tgtctgaggt tagccaagcg tgatcgccac agtttccatc gtctttcaaa 8520 atcggaaacc gacctaattc tcttttggtg cgtacaaggg ctgtaacgta atatatcaat 8580 aagttcgtca actgtttctt taagtacagg ccactccttc gttaaaccgg acatctcgag 8640 gcatgatata gtttgttcaa aaagtccacg aatagctgtt ttattaacat aaggccaaaa 8700 ttcaggatgt tggtaaggta tacgataagc catgatttcg agtccatcat cggcaatagg 8760 ctgtggatca taggcattta cccaatctaa aattcctgtt gataaggtat aaggagaaga 8820 aggggggaaa taaatagctt cagcacagcg ccaagctgat tccacttccc ataaagaatc 8880 caaaacaggc tgacaatctt tttcaccctc gttaatacgc gactgcaact cctctaaaac 8940 ttgtataatt ttagagcgga agagcgagct tattttccca taaaactgcg ttaacaaaag 9000 caaatttgcc tcgctgtcca agataggagt catataggta tcttgtaatt cttcccataa 9060 ttcatgccat gcggtcaaaa ggtaatttgg ttcaattaga gtagaaggag tactaaattc 9120 atacaccaga gattctactt cttcaaattt atcagacttt aacgtatttt cgtcaaattc 9180 tttgttatta atgtacgcta gtccttttct caaaaaagga tgcaatttga aggctaccgt 9240 tcggcctttt gaacgccagt cattcaactt tccattttct ataggtgcat tttgtaaatg 9300 ataaacagga agatccactt catccgaaga ttccatattg gaatgttagt agttccgaag 9360 aaagtaagaa aaaagccttg taagatttgg attaaccaaa atataaaaga atatatttat 9420 ctgctttccg atactcaaaa aaatcagtaa gtattaggaa tttgcatgtg tccacctgca 9480 ggcgtttttc agatgtcaaa aaggatggct cttgctcgac caggagtaat ttagtataaa 9540 aattaaatct cacttgattc ttgttggttt tttttgacaa cgaataatac taattatcta 9600 aggaagagca gacactcctt taaagatgct ttaatcgtaa agtaaggttg atcgaattgg 9660 agccaggcta caatatgaag tttgaactca gatcgtcgca acaaaaaata gcagtcttcc 9720 tgactttctt taatgttatt agaattaaag gaattaaaat aaaaattaga aacgaatatg 9780 ccgttgcttt tatcttcgtc aaaattcgat gcatgatcgt atttcatgga ggcataaaaa 9840 aattgatcat gtttgcaaat taatttaaat tataaattgt aataaatttc gtttctatat 9900 aaatttgtta tcacttattt taccagtgaa ttaaccaaga ttcatgctta catattcgat 9960 aaatcttcga tggactaact acacacgtaa ttaacgtttc gaaccttgca actgactctt 10020 ttaaagaaca ttacctgtct gttggaagga cagttgataa tcaaaaagta tttctataat 10080 gaagaactgt ttacttaaat gattttaaaa ttcattgcaa ccatgtccac acttagacaa 10140 tgatcattta actttagcaa cttaattata gccatacttg tttttcggat tatgaacggt 10200 ttatacgccg taaaagtccg caattgaatt tcgtatcttc cagttaaaat acagaattta 10260 ggctgtgctg ctaacgaaga aaagtacttg caatctagta tgaaaatacg ttatacatta 10320 aaaataagtt tcattgagaa ctgttggcaa ttaagcaatt tatgtttaat agcaatattt 10380 gtaaatgcaa gggtaactta cagagtttga tgctatatat atcattattg aagggattct 10440 gaaaaaatag aactaaacag tcataattga atctttgcat accgcttttt tgtcaagata 10500 tatgccatca aagtacaaat taattaatat tatattaaac agaattagtg tcgatttatt 10560 atcatcgata atatgcgttc aaagtcaata aagtatctat aacaaacaaa ttaagaatgg 10620 tcgtgtatta tttttccttt gcgggaatta cctttgttgt taaatgtact caaggaacac 10680 taaaggaaag aaagacctag ctcaaaagac agcaggaagg agcaaactgt gcgtgacgat 10740 cgctaaaata aaaaattaaa ttactcctta ccaaattaaa acctttggaa caaaacaaag 10800 tatgatcact ttagattgtc tacctagatg ttctaaggct ttaataagtg aatataatat 10860 aaaaaattta cttaattgtg ttacaaacga atgtatcaca ttgcgttttt gcctagtttg 10920 tttacgtatt taacgaatca ctgcaaatga ttttaacgag ttaaacagaa aaaactttcc 10980 aaacaccaac ataaacagta tgttcgactg attttaccct tttgttattg ctttggttta 11040 atttatattt tctgttataa cttgctgaat ttttgtatat attttttgaa ttggaatatt 11100 acgcttgaga gctttggttt atttttttgg taatttgtgg atatctgaga ataaagcctt 11160 cttgcatgta tacaatcgtt tttttgaaac attcttacat cataccatcc aagaatacca 11220 ttcaagtatc tttaaaaagc catgtctgta ctaattgaaa ctacagttgg tgatttggtt 11280 atcgatttat tcgtcaagga agcgcccaaa acttgtgaga attttcttaa attatgcaaa 11340 ttaaaatact ataatttttg tccattttat aacattcagc acaattatac ctgtcaaaca 11400 ggtgatcctc ttggaccaac tggagatggt ggtcgatgtg tgtggaatgt actgaataaa 11460 ggaacacgct ttttcaaagc ggaatttaat ccttctttgg tacataataa aatgggcttg 11520 gttagtatga gcacagcaac tatatcttct agagatgaca aattacttgt ttgtggtagt 11580 cagtttataa taactttgtc agacaattta gaaggacttg atgaaagata cccaatttat 11640 ggacaggttg ctgaaggctt tgacacgcta ctgaaaatca atgacgctat atgcgatgaa 11700 gagggtcagc cttatcgtga tattcgtata aaacacacaa ttatactaga tgacccgttt 11760 gaggatccac ccgatctagt ggagcctttg cggtcaccgt ctccaacgcc tgaacaatta 11820 gctacggtac gtatagggga aaacgaacaa attgagtcag aaacatcgga agataaattg 11880 caaagagaga aggaaatgga ggcagaagca gaggctgtta cactagaaat gattggtgat 11940 ttaccctttg ctcatgttgc tcctcccgaa aacgttttgt tcgtttgcaa attaaatccc 12000 gttacccaag atgaagattt agagttaata ttctcgcgat ttggaaaaat tatctcctgc 12060 caagttattc gagataaaga aacaggcgat agtcttcaat atgcctttat cgaatttgat 12120 aacaaagaaa gtgttgaaaa agcttatttt aaaatgcaaa atgttttaat tgatgattct 12180 cgaattcacg tagatttttc ccaaagcgtg gctcgttaca gacaatatta caactccaat 12240 agggaccgaa aacgttcttc gtctcgtagt gatgatcgtg agtaccaccg taggtctgat 12300 ggtcgttatg acagatctaa ttaccgagac gactataggc atcgacggaa agagcgtgat 12360 catcgtgacg atcaaagttc atttagaaat gaaagatttt ctaactacta cggtgatgat 12420 cgttcatacc ataaacggag aaatactgga aataaaaatt gtgatgatca cttacgagat 12480 aaatctcctg aacgaaggta tagatatgat agacgttata gagatgatag atatcgatag 12540 atctttatta tattcgtacc tttcttgtga atattattta tgactgatga aattactaaa 12600 acatagttga ataattgatt aagacttcaa atgtatggaa tgaaatctac attgcttata 12660 cttgtaaaag caaaaaatca aaaaaaatcg tcgtactaaa ttcgagggcc taagcatgaa 12720 aagaacatgt tacgagtaat ctccataaat gcggcacgtt tatgagggaa attaaattcc 12780 aaacgtttgg agtaattttc ttcgatcaaa tagttaataa attttgaatt gtcaattctt 12840 ggttcaagaa gtacacgctg agtacgagga tcatccaaaa ataacatatg cgtaatactg 12900 gataaccaca cggggacacg gtgaggcccg cgaaatttgt cattacctac aagggcatgg 12960 aaaccacgat catgtgtatg ccaaggctga gcaaatggag caattctatc ctcaggaacc 13020 caataaactt caaaataagc aaaaggcaca tcattgaaac agccaatgac accaaaagaa 13080 tgaggatcgt tttgaagtgt tgttaggtat tcatgatgtt gatcccatga accagactcg 13140 ttccaaaagt attcaactct cggtttgttc tgccactcat ggaaatactg cagatgttgc 13200 tcaatgtcaa gagatacgaa ggaaagtgtc tcattcaagc taggtataaa tcgctcatac 13260 agagtggaac caggttttgg acatttggga cgacgaatga cttggttcgg taagtaagat 13320 aaaggccaat cactgcatct tgtgtacatc caaggagacg ggatttgcca aaaagacata 13380 cggtcaatcg agacattacc ttctaactca ttgtattcaa caggaaggct caaagttcct 13440 ttttgacttt caatgtttgc ccactgtaga acgacttctg ttctcaaagt agggaatacg 13500 tagaaaatag aaagaaacgc caactgcaaa atttcattaa cgtccatgtc ttggaatcca 13560 tttaaatcaa tatcccatgt tttggactct tcacgatacg ttaaaagcaa tctcttattg 13620 tcatgttcta aagttatcaa actctcttgg acagctgaaa gcttgaaagg ctcggtctta 13680 gaccaaacag taaaggacat cccgaatgaa atttctcgaa ttttacttag agttaagata 13740 tattgttata gatattgccg tcaactatct aattacaggt gaaatcttaa acaaaagata 13800 gaagcagcga cgctaatttg tacaatttgg aatcctcgag caatattaaa acaaatagga 13860 attagtttta attgtttaca tacggtgagc aatgtacgtt atttacaaga tggctggtgc 13920 acagtagcac ataaacagtg atgtcaagag cctagtgcta agaatctgta aacgtgataa 13980 cgatttagta ataaaaaact ttaaaccaca tttaggtatt gtttaagaaa ttcattaaat 14040 tacaaaaagt ccaaaaagca gtcacaaaca acatcaaaca aatggctatc ccttgtgaga 14100 gcctttcctt accaccatca gtcaccaaaa tttctaaaat gagtgaggcc gtgacaatta 14160 gaactcgcaa gtttatgact aaccgcttgc ttcaaagaaa gcagatggta tgtttatttg 14220 atgaagcttc ccgctatttg accttttggt ctatttttaa ttcaacatca gctaacggaa 14280 atttataggt cgtcgacatt cttcaccctg gcaaggctaa cctttccaag aatgaaattc 14340 gtgagaagtt ggctcaaatg tacaagactg attccgaatg cgttcaagcc tttggtcttc 14400 gcactcattt tggtggtggc agatctaccg gcttcgcttt gatctatgac tctactgagt 14460 ccatgaagaa gtttgagcct cactaccgtc ttgttcgtgt tggtcaagct gagcctatcc 14520 aaaaggttgc tcgtcagcaa cgcaagcaac gtaagaacag aggcaagaag gtctttggta 14580 caggcaagcg tcttgccaag agaaaatcta agcaacaaga ctagagtaga tacttacttt 14640 aggttccttt ctcgccaaaa actcaataca ttctgtccct cgcgtaaaac tattattgta 14700 aattttgttg tttccgtacc ttgtaactga gattttttat tattatgcat tgagtatatg 14760 tacaattcac ataacgctac aaatacgttc gaaatatctt aaaatttatt ctgtgtgctt 14820 ttcatgctta tatatatacc tatgtaacat ctatgcaaac ataccagcat attcaacaaa 14880 ttcactcagc tttccaatat acacacgaat taaaaaacca ttatttcctc tttcaaattt 14940 acaagttgtc cttcaaggag ttgctctatt catcacaaac gcttgcgccc gcgctgaaag 15000 cgtctccata gtaacttcgt caacattcaa actggcaccg ttcaacgtca atagttcagc 15060 aattaaatag ttgttcttca ataaagcctt tacaacagcc ctttgataat taacgtctgc 15120 tcccagtgct aaacatagga cagcttcttt cagattacta tgctcaatag actccaaaag 15180 gcctgtgtta ggatcgtgtg aaaatgacga tttaataaat cgtttataca aatacttgtc 15240 ctttacaaat tgaacccgac gctcctgatt ttcaaagttc ttgattttcc agtccgttat 15300 tccaccttca tagatttcat tgacaaaact gtttccagtt gcatacaaca aatccacggt 15360 ctcgggatta aatttgtcaa gagtcaaaga tcgaatcttt gtaatatgag tacccaaaga 15420 tctatgtata ccagaacaat ctgttcttgt tagtaaagtt tagaggctgc atactagcac 15480 ttacctatgc ataaaactac ggggaaatta atagcacacc attcaaccct cgcagtagtg 15540 ttacaatccg cacatgattg gtcgctactg tgcatctctt ttaacgtttt tacaagtgaa 15600 ggtgattttg tttgtttttt ctcttttgaa tcggaattat gacgactcgg tgatgttaca 15660 gaagcaacac gttgaagagc tttaccaatt gtcgaggtgg gaccgtgttt caccgaagtt 15720 tcctcggaat tcatagacgt acccttcccc ttttgaacaa tgctttcact aatagagtat 15780 tgaatagcct caatccaaga atgcatttcg gcttttgaag tagcttgata agttctttta 15840 gtttgggggg tgattacttc aaaacaaaat ttcctactca cagactgggc tggacgaacg 15900 gtggccatta aaaggtcaat cggttcagtg tgtaattcca gtgattgctt ccaattagca 15960 tattcacata tttttccgtg atccaataca acccagtatt tatgccaccc ggattttcca 16020 acaacctgca agtcgctagt cgacttcgaa aaagcaagta ataacccctg cttagcagac 16080 gtgtcctgat caacctttgc tttgtatgct tgggctgcta tttccgcatc tttatcttct 16140 agttcacgac tactagtttc tatgtatctc cttctttctt ctcgttcagc ccttaataat 16200 tgaaattctt tgttggcctc tgtaacaatg tcttgcaatt gtattatact aggacgcaaa 16260 gcatcgatat cggttaaaga ggagtgaata agattgtaat catttgcagc aaaagatgtt 16320 aggacggata aaacctcttg gcctttcctg ccaccattaa tatcctgcat ataagaataa 16380 tagtcaaacc gagaaagctc aaaatctctt ttcttagcag caaatttaga ttccttagtt 16440 ttatctgaag atgtttcttt ctcgctttta gaaaggtagc gtgacaatga ggtataataa 16500 tcacgacttg tttcctcaaa atctttcttt ttcgtagata cattttttat atcagtatca 16560 taaattttac gcaaaggctc aataagaaag tttcttagca aacgagcacg atcaatatta 16620 aaggaatcga aagattgagc agctgcagca taataatggt ctaagaaggg tttaaatgcg 16680 ggcgggttaa tggtagcaac acgttcaaat gctgacatga gctctttata agacatatat 16740 agtagaccat gagaatgtgc tacgtgctcg atacgtttta ttaacttttt caaaaccatg 16800 cgcatatcat gagtagttcg ctcataatta agaatggtag cacgaaacag aggaccatct 16860 tcgggttcgg tttggtcaat atctcttgcg actggattcg tgagaggagg agaattgata 16920 ggaaggggat ctacgttacc ggataaaggt ggagcatcag atatttctgg actagttgca 16980 gtttcctctg caagatgcat gggcattggg aaaggagtag caggagttga gtcttgatct 17040 gattctgtaa cgtaaaactg aaaagttttt aaaggaacca agcaatttaa acgtttatcg 17100 tattcggcaa actgcatatt tagtacaaat tggacaactc aatacgaact caaggaactt 17160 acgcatagat aaattggtga gccgccattt ctaaagtata aggtatgtaa cgattgatta 17220 gaccaggtcc attcaatctt tttagaattt tcattcgaat ggaattcaat attgccgatt 17280 aaaaagactt gatgattgtt ttggaactga atcaaaagtt agtaataccg ctaaaagtaa 17340 aaatcatttc tgaaaaaaga gattctaata aaggaaaaga aaaccatcat ttttttagac 17400 ttcttatttc aatcataacc aaagacatac attcgcatca ctagaaaatt cgcgcgtgat 17460 tagcctatcg agttgttgag gtgaagtacc atatacgcat gtaaggttgg tgacatctcg 17520 ttttccctct tgtgcatgaa attctagctg aaagcgaaga gtcaatccgt cttcctcttc 17580 aactttaact ataggaccct cctcttcacg tagctgaaga tgtgttagca tgtttgacga 17640 acggcaaacc ttcatacctg gataaattca attggttcat tgttctttcg ggaataactg 17700 tattttgagt attcaggaga tttcgataca ttatgaacct gcaaactggc attgtcattt 17760 gctgagccaa aggtaaccga ctgaatcttt actttagcag agttagatca tctgtagttc 17820 acacgaaaat ttaaaaaaag tacatacatc tctcaaaatg aacaggatcg acatgcccag 17880 tcatctcgcg tacttgagtt ttcgcaagct gtacaactta aagcgctgta tgcgatgagt 17940 agaacaaagc aaattgtaac aggaaaaaga gaaaaaccga gctaaaaact ctcgaataag 18000 aaaaacaaga aacgcagctt ttttacgtaa atacaacaaa taagaaatct attcggcgct 18060 agcagtagtt ggtagtaagt aagtaccaac caccaaggcc aatgatgatg attacgaatc 18120 catttagtgg gttgaagcgc agaacataca ataataatag tgtattggtc tgtacttcgg 18180 taaataggct attcacagca atgctctaag cgaaggagac tagataagct ttacgctgaa 18240 tttttcaatt tttgtggtac ctctaaaatt aatgttacga atggctgggt aaataaaaga 18300 ttgagtattg ggtcaaccaa atacaagatt ctttgaagaa tactgtataa ctgttatctt 18360 ctgttactaa atattctttt gttaattttt cattgatttt tacgttaaag tagcatggct 18420 tgcatgatga catgaccctc gcttgcaaat ttttatacat tgtttattta tttcgtatca 18480 gatgaatgac gctttgtcaa tttatttgtt tgcttgtcac acttctgtgc tatacaaatc 18540 atgaaataaa ataatttcaa gtttaaaaac gttaattgca ttacttgatc aacgagtgaa 18600 ctgtatacgt atcgatgaat aagtgtaaat aagaaaggat aaatgatttt aacatacagt 18660 acgaaagcaa ctagatagtt aatcttcatt cttttttttt attcgagaac cgaacttcca 18720 taaagatcat tgcaatggcg gaattgccat caaccattta taaagcggga tcataaaact 18780 ttgagcgacg gtattcaatc atcgaaactt ctcaaaaggt tgaactaaaa aacatttgag 18840 attcacatgt aaagagctaa ctaccatgtt gaataagcct cgattttggt tatctagatc 18900 acttgataat ttatttcgct aattatttta tatataatga gtaccgcttc aaagttttta 18960 agtaaacaaa cactagatta gataatttca ttaatttaaa aaattaactt aaaatattgt 19020 tagttgactt tactagtttt ataatgcatt aagttcacaa atttactttt cttactttgg 19080 aaaaacctac gggtctaaca aaaatatttg taaataatag caataaggta actatagtga 19140 attaaacaaa tgatcaagga aataatttaa atagatttaa aaaaaatata gctgtttaac 19200 gaaaagaatc tactgataac cttctttcca ctttcattac tcagaaacca aattcgaaca 19260 actattttaa gcgttgttct gcgtcactga agaataccga gaatgtagga attgtattat 19320 ttgcatatag tgacaatcat cgaaaaattg tgaacagtaa tagttaaatg aaattctcaa 19380 aaaacgactg tgcaacctaa acttggtatt catttaacta aataacaatg tacatagtgg 19440 gtttgatatt tcttgaattt ttaaatattg ggaaatgatg ggtttaatta ttgcaattaa 19500 tagggaaaag cgtgtgattt aaattgaatg tacttcaatg tcagtatata aattgcttcg 19560 atagccgaaa ggaaaagcta ccgataaaag ttttggggat catcattaac atttttttgt 19620 aaacaaattc ctagtgatcg ggttttagaa aaaaaaaatt attaaaatac aaaataaaaa 19680 tggtcaatta ataactttca ttaatttatt actctaccat ttctacatgc tgatttagtc 19740 attaaatatg catatagaaa agttgaaaaa cgttttgaag aaagtcaact gcacaaaaaa 19800 attctataga gtaagaaaaa tgaaaaaaaa aagaccaaag aaaaaaatga catccagcaa 19860 ttatggcatt tgttttaata atttccaaga gctgcataac cagatagata gtataaataa 19920 aattatgaga gaccatgtac tggaaataac aattcagtaa accgatttac aattcagtaa 19980 agtgatttgg agttacaatt gaaattaact gaaattagat tgccccaaat agattctaga 20040 ggtaaccccg attgtgaaac cgatgagctt cttaatgttt agaaaatgga ccttaaatta 20100 catgcaaata ggaaatctct gttttatttt caatctcaaa atctaagcaa gcttgaacct 20160 tgagaagaca tattcaggtt gtattttttt attttttttt tcgaaggaac agcagacagt 20220 taattgtaat taggcgaacc catagagtta aggaaaataa ttattataaa tattgcaatc 20280 caagcttaaa tcgactttta ccttttaata aaatgggcgt tttggcttat ccatatacac 20340 tcccacaaat tatgacactt tttagcgact aaaataaagg aatatttagt aattgagtac 20400 tgcagtctaa ttaaataact attatagaac ttttgaagca ttttcgggag ttccttgcta 20460 attaaaaaat gagaaactga aactagcttt tcatcttgta agatcattag aaaaaggatt 20520 taacatattt aaatcataat aataatgaat attgttctta tagcgtttac atatatggct 20580 ttgttaatta cagtccattt ttcttggtgg gaaggcatca aaaaaatccc cctggccctg 20640 taaactacac ctaccacttg ccaacttcta cttcgaccgc aaaaagcgta caaaacgcca 20700 aaaacgagtt gatttcgtgg aattaaaagt aaattacctt ttgaagaatt taaaagattc 20760 gggtagtact agtgtccaag aacacctacg agcaagtcga aagaaaagtt tttttgttct 20820 gaaaatttct acattcggtt ccactttttg aacaaaaaaa gaaaggaatt ttttaaataa 20880 ctaaatttta ccaaaattta ctataatttg cttgtaaaaa tggcggaaaa tcttgatatt 20940 tcagaattgt caccgattca cccagctatt atatctagac aggcaacgat caatattggt 21000 acaattggtc acgtagccca cggaaagagt acagtggtca aagctatttc cggtgtgcac 21060 acggttcgtt tcaaaaatga gttggagcgt aatatcacaa tcaagctggg ttatgctaac 21120 gctaagattt acaaatgttc caatgaagag tgtcccagac ccggatgtta ccgttcctac 21180 tcttccaaca aggaagatca ccctccttgc gaaatttgta attctccgat gaacttggtt 21240 cgccatgtat cgtttgtcga ttgcccgggt cacgatattc ttatggctac tatgctgaac 21300 ggtgccgctg tcatggacgc cgccttattg ctgattgctg gtaatgagtc ctgtcctcaa 21360 cctcaaacta gtgaacactt ggctgccatc gaaattatgc agttaaagca cataatcatc 21420 cttcagaaca aagtggattt gattcgcgaa tcagctgctg aggaacacta tcaatctatt 21480 ttgaagttta ttaagggtac cgttgctgag aactctccta tagtccctat ttctgcccaa 21540 cttaaatata acatcgatgc cattctcgaa tatattgtta agaaaattcc cattcctgtc 21600 cgtgacttta ccactgctcc ccgtttaatt gtaattcgtt cttttgatgt taacaagcct 21660 ggtgctgaag ttgatgacct taagggtggt gttgctggtg gttctatttt gactggcgtt 21720 cttcgtttaa atgatgaaat cgaaattcgt cctggtattg ttacaaagga tgatgatggc 21780 cgcatcagat gccaacctat tttctcccgt attatctccc tattcgctga acacaacgat 21840 ttgaaaatag ccgtgcctgg tggtttgatt ggtgttggta caacagtcga tcctactctt 21900 tgccgtgccg atcgtctagt tggtcaagtt ttgggttcca agggcaacct tccagaagtt 21960 tataccgagc tcgaaattaa ctactttttg ctccgtcgtc ttttgggtgt aaagagtggt 22020 gataaaaaca ccactaaagt tcaaaaactt gccaaaaacg aagtgttgat ggtcaacatc 22080 ggttccactt ccactggtgg ccgtgttatg atggttaaag cagatatggc aaagatcctt 22140 cttaccgccc cagcatgtac cgaaattggt gaaaaggtgg ctctcagcag acgtattgaa 22200 aaacactggc ggcttatcgg ttgggctaag gtggttgagg gtaagactct aaaagtttag 22260 attttatcgt tgtaaacatt gtataagatg aattctcatt ttttaacttt taaaaaataa 22320 acaatggtaa tgtctacggt taaacttaac gatgtctcgt acacggtgtg tgattttagt 22380 acagttgatg aatcatgtag ttgatacaca gtgctaatag atgcgtatct acatccctat 22440 tttatacatt cggatctctg tgcagtattt aatgtttcca ttattaatta gttagactat 22500 tttcaacatt tactctacag cgaatttata cctatttagt acacctgatg gtactagttc 22560 cttatagtaa agcaataagt aaatagaaga gtcataaatc tatatttact attatttgat 22620 tctaatcaat tatgcttatt tacttgactc tttcgttttg tggtatttca ttcatagtat 22680 gtatctgtaa aatatgcttt cacttcccag acttttggaa gcctacaaaa aaaaatatga 22740 aaatttaaag aaagtgaacg attcaattct ttgaatacaa aaattctatc aaataagcga 22800 ttttgatctt ttcccaatta gcaaactcta aggcaacgac attattcaga gccctaacct 22860 aaacaagtga ctgttaattt cgaatgcaaa caacactagg agacgcaaaa cgagctacct 22920 acatcaaaca ccatggcaga gaaggctcaa aaccccatga aggagcttcg tatctccaag 22980 cttgtcttga acatttcttt gggagaatct ggtgatcgtc tcacccgtgc tgccaaggtt 23040 ttggagcaac tttcgggtca aacccccgtt ttttctaagg ctcgttatac cattcgtcgt 23100 tttggtatcc gccgtaatga gaagattgct tgccatgtta ctgttcgtgg tcccaaggcc 23160 gaggagattt tagagcgtgg ccttaaggtc aaggaatacg agttgaaaaa gcgtaacttt 23220 tctgccaccg gtaactttgg ttttggtatc caggagcaca ttgacttggg catcaagtac 23280 gatccttcca ttggtattta tggtatggat ttctacgttg tcatggaccg ccctggtatg 23340 cgtgtagctc gtcgtaaggc ccaacgtggc cgtgttggtt acactcacaa aatcaatgct 23400 gaggacacca tcaactggtt caagcaaaag tatgatgccg tcgttttagg aaagtaaact 23460 tcatttggta ctactgtgct tacattcaat tgaaaattaa ttcctcatct tgtatacttt 23520 agtgaattcc aatagcgcct tgtaatttcc aaactgaaaa aacttgtatg agcagttgta 23580 tagctagtag tttacaacgc aattgacatt gacactgata atagaaaatt gataacctgg 23640 aagattagaa catatgcgtt tcttctgaga tcgtaatgca cttcaagcat gaaacgttag 23700 ttcgctggtt cagtgaaact acgtactaaa atttagtagt ttagttgtca aaaaaagggt 23760 aatttaaaaa tcgatctata aaaagttcgt ttatgctaca gtcatacgaa ttaatcaata 23820 tacacaacct tccagctaag tgccagaata ttaccttaaa caaaatacct attcatttat 23880 aattaaggca aacgccaata ttttttcctg caatcgttta ataaacctta aatagttcaa 23940 atggaacaaa ttactcagcg acctaacaaa ataaaacttt aaaacatttc tccaagccgc 24000 ttcttttaaa cgcatctaag cacacatcac ccacggatga aatgaacctg aagcagaatc 24060 caacaaactg gaatcgtaaa tttactcgtg ttcaagaaca gcacacaaat caccaccatt 24120 cacagaatca ccctgaacaa cggccaaaga cttgagcaca ccactgtgag gagcactaat 24180 aacaatttcc atcttcatag cacttaaaac agcaataata tctcccttct taaccttcgc 24240 accttcctta acacgaattt cgacaattgt tccactcatg ggggctgcaa cgtgtccagg 24300 attaccagga tcagcacgag gtctggtaac agtttctata gctgctttct tatcttcaac 24360 agtaacatgg cggttctcac cgttcaactc gaaataaact tcacgttgtc cagtacgagg 24420 gttcaatggt ccaagagcga caaatttaac gattaaagtc ttaccttgat caatttcaac 24480 gtgcatttct tcgttcattt caggtctaga taagaagaat ttagtaggaa cagtggtcaa 24540 atcaccatag cgatcgacaa attgacgata ttcctcaaag acaccaggaa attgggtgta 24600 ggcagcgata tcacaatctg aagaaacacc aaacttctct gacaataatt tgcggatagc 24660 atcgaaatca gcagcaggaa ggaatttacc tggacgatca gtcaaaggtt gacgacgacc 24720 tttaagtaca ttagtacgca aaggctctgg aaaaccgcca tatggttgac ccattaagcc 24780 ttggaagaaa tcgagtactg aagcagggaa gtccaaagtg gtcgcacgat tctcaacatc 24840 ctcagcacta agtttatttt gaaccataaa ttgggctaaa tcaccaacca cctttgaagt 24900 gggagtgacc ttaataatat ctccaagcaa tttattggct tcaatgtacg ctttcttagt 24960 ttcagcccat tgagtgccca atccaaggga ggtagcttgg aatttaaggt tggttaattg 25020 accaccggga atttcgtggt tatacacatc tgagtcagta cccttgattt cagattcaaa 25080 cggagagtaa agcaaacgca tttgagccca ataactatca atttcgcgta attgattgtt 25140 atcaaactcc aattgcttat cagtaccatc gacagaggcc aaaacggcgc caaagctagg 25200 ttgggatgta agaccagaca tgctatcagt tgcaacatca acaacgtcag ctcctgcctc 25260 caaagccgca gccatggaag caacagcagt accggcagaa tcgtgggtgt gaacatgaat 25320 aggtaactct ggatgtttct cccgaatggc agaaataaga agacgagcag ctttaggttt 25380 cataacgcca gccatatcct tgatacctaa aatgtgaata cccatttcaa ccattttatc 25440 aacaaggtta acatagtaat caaggttata cttcttcttg ggatttaaca tatcgccaga 25500 gtaacacata gtggcctcaa caacaccgcc ggcgcgcttg gcagcatcaa ttccaagaga 25560 aaggttatta acatcgttca aggcatcgaa aacacggaag atatcgatac cgttcttttt 25620 ggcttgttca cagaaaaagt aaataacgtt atccggcaaa cttgaatagc ataaaccatt 25680 ggcaccacgt aaaagcattt ggaaaggaat gttaggaacc aacttacgga gtctacgcaa 25740 acgatcccat ggacattcat gaaggaatcg catagagacg tcaaaggtgg cacctcccca 25800 catctccaaa gaataagcgg aagcaagggc atggctcgta tatggagcaa tatttaccag 25860 atcaatggta cgaacacggg tagccaataa ggattgatgg gcatcgcgcc aagtggtgtc 25920 catgataaga ccacgcttgt gatttctcac agccttggca aaggcagcag gaccgttgtc 25980 taacaataat ttacgccaac ctttttcaga tggatgagaa acatcaattt gatttcctgt 26040 actgtctaac aaaacgggca tgacaatctc cgacttaaga gctggctcac cattttggcc 26100 cttaatagag ctgccgttga cagcaagatc accgaggtag gccagaagtt tttgagcgcg 26160 attacgggaa cgataaagtt gaaacaattc aggagtgtca tcaataaaag ttgtccaaca 26220 gtttccttgg ataaaagtat cgtgcatcaa taaacgcaaa acaaaaggaa tgttggtttt 26280 gacaccacgg acacggaact cgattaatga acgaatcatc ttacgacggg tatattcata 26340 tgtagcatca tggcatgtac acttgacgag catagagtca taatgaggag taatgacaga 26400 acccgcgaaa ccgttagcac catccaaacg gacaccattt ccaccagcgg aacgataaac 26460 ttcaatctta ccaatgtcgg gagcaaagcc attgttagga tcctcagtgg taacacggca 26520 ttgaatagca aagccgcgag tgctaatttt atcttgggtc aaaccaattt ctggaagggt 26580 aaaaccagca gcaacgtgca actgagccga tacaatatcg acaccggtaa tttcctcagt 26640 aatcgtatgt tcaacctgaa tacgaggatt aatctcaata aaatagtgac gtcctttttg 26700 atcgagcaag aattctgcag taccggcgtt gcaatacttc acttccttgg caatcttgat 26760 ggcatcgtca taaagtgctt gacggatctt aggatccaaa tctttggccg gagcaatctc 26820 cacgaccttt tgatgacgac gttgtacgga acaatcacgc tcatgtaaat gaatgacatt 26880 tccagcctta tcagccataa gttgaatctc aatatgcttg ggtttatcca aaaagcgttc 26940 aatgaacaca gtgccatcac caaatgaagc aagggcctca gaacgagcac gctcaaatga 27000 ctccttcaag gtatcggcag aacgaacgac acgcatacca cggccaccac cacccatggc 27060 agccttgatg ataacgggga ggccatattc cttaacaaaa gcctcagctt cttcatagtg 27120 ttcgacggga cctggagtac caggaacgac tgggacacca cagcgaatgg cgattgcacg 27180 agctttcgtt ttgtcaccaa gagagtcaat gacttcgggg gaggggccta caaattgcat 27240 gccagcttcg tttacctttc tggcaaattc ggcgttttcg gaaaggaaac cgtatcctgg 27300 atgaaccaag ttggcaccgg tgcgtttggc gatgctgacg atttcgtcaa tagccagata 27360 agctcctact ggactgtact gaccgacctt gccaattgga taggattcgt cggccttttg 27420 acgatgcatc gacagtctgt cttcatacga gtaaatggcg acagtgtgca tcgaaagttc 27480 atgagcagtt cggaagacac gaatagcaat ttcagatcga ttagctacca acaccttggt 27540 aaacttctct cctaacaagg aggaacgatc ctgcaacttg ctgaaagggt ttgtgttggt 27600 actttgattg tgcaacaacg catcatattt agaagtcatc tttaatttta tatcgcccca 27660 atactgagac tagcaaattg caccctcttt gctaaatacg aacgtttttt tgcagagtag 27720 ctaacgctag atgtagttgc tggttaaagg agagatgact cgatatgcaa aattacgcaa 27780 gactattgct tcgaagatag agggtttgat gaaaacggca gcctctgcgt tcacaccaat 27840 cacacaatat aacgaggcat aacggaaccc tagctggtct ccttagctga tagccgaaat 27900 ataggccaat cgtagttagt aaagataagc gtaatcgcaa ttcaactgtc ggtaaaaaaa 27960 atcaaaaatt tgattggaag aaaatgacct aaccgaatac agatcatcat gattagaata 28020 tgtacttgta tgattagttg agagcttcgc ttgtctcggt aagtccgctt attcggtcga 28080 gcttgaaccg gcttaacgga catgcaagga gcactaacaa gcgacagtaa acagtagatt 28140 tgaaagaaga aagtgagatg gaaaataagt aaagaaaata agggttgtac cggctttaca 28200 tagaagccaa gagagatgga aaacagagga attgtgaacg ttctccttat tcatatttcc 28260 ataaagcttc tccaatgacc tttattgaga agatttgatc gccttgatct cgcggtgctt 28320 ttttgttgac gacaaaaata tcaacaactt aaattttgaa gcttttgatc atctctccgc 28380 tgtgttctct tgacgataag aaaagcttta tgcgagaaat gccttttgga tagcgcacca 28440 gtcgctacaa gtgtaaatga tttttttacc tggcacagct ttttgaacgg ggaattcaga 28500 tatatcaaca agttgcacat cctcgaatct ggacaagata tcatagtact tttgatttga 28560 acgcatcaaa atgcttatgg gggatatctg gaggcaaccg aaatcagtag gggaatcacc 28620 gatatagaca acattaagtg gagacgaaac tgcgtctgtt tgcactattc gccgaaactc 28680 tcgtactttg tccgtagaat tcattagaag tgaacttgca tttctcgcaa gtatcctacc 28740 gtttgttgtg tttgtagacg tatcgaagtc aaagtcgttg gcatggacac acaacaagtc 28800 tgcggttaag tccgtatggt gaagcagggt ttgttcgatt actcttgcag accaattgac 28860 ggaaagaacg tggaaaatgg ttttgcttac acggagatcg ggcaccaaag cattgatgaa 28920 ctctacaaat cctgcgcgca gggtgatcag ttgtacgatg ttgtcaaggg caccctccga 28980 taatccggaa aaatattgag atttttcaat tctttttata ctagcttctt cgagatatcg 29040 acttcctcct agtagaggta aataagatgt tagcgtggta gaatgcggta atgcttcacg 29100 ccaagccaaa tactcttgcc agtatttatc agatattacg ctccattctt cgggcttatt 29160 aacagcttca gctaggaggt ggattgtatc gtaggtggta attgtctcgt caaaatccac 29220 tatgtacagc atttgccaat ttttatatga gaaaacgata ggtgtttgaa aatagatgtt 29280 cacgtagaaa aaaccaaaag aagctatatt aatgaatgga aatgattagg aatgctaatc 29340 tctttcacca attttgaagg aatagagatg ttttctaaag gcgaagcttt taagtctgaa 29400 ggctagaaga agtagtatgg ttaggcagaa gacttgagca tgcatgtgtg tggacgaaat 29460 ccaaaaatta aaccggcgaa tgatttgagc actgaaagga aaaaagaagt cttgtattga 29520 attaattcat agagtatgat aaaaattgat agtaaattca ttggtatact aaagtgatgt 29580 agaaaattaa gaaatcacat agactacttg agttacgatg atttattagc atgcatccgg 29640 accgtaaagc aaaagaaatt aaatatttat gaaaaaaaaa ataaatgatt cataacaagc 29700 agatgaaaat gatgacgaat taggactctt caaaataaat gaagattata cattacaaac 29760 tttggtctga ctttttaaag cacacgattt gctacctttt tttgactgac tttttaagaa 29820 cctttccgac gtttagcctg agctgaatgt ctgacaaaga gtcccacgat acaacaggtt 29880 tggaggtagg gtgaggatta taaggcaaat agcaaacggc actcaaaaag gttatgagcg 29940 atctctgtaa gatacgacag aacccctttc tggggttcag tggtgcaaac ggtggtcgcg 30000 aaatttgtgg atttcgaagt gtgacatcta agagaagtga atgcaagtga tgatattcat 30060 gtggtaagag tgggacagca atacgaggca aaagttcgtc gtatgccctc ttgcaactaa 30120 ggttaatatg gtaagggcga tctttgtttt tctctattaa accgtcaaat atgacgctgg 30180 gcaaatggcg gatttttgca ttttccatat ttatctcaaa aacggccgat aatagggatg 30240 aaatgtaagg aagacgaact ggtgaattag atggtaaact tttgggtatc tttgaaggtc 30300 gaattttatt atcttgtaaa taatgaagac gcctatgacg aagaggacct gtttgtgaat 30360 aagcgtatcg taaagtctgc catatagctt gatggtcgcc atcattggcg cgctcaatac 30420 gacatgcaaa agtttttagg agattgcgaa accgttttat gcgccgcttg tgaggattag 30480 gatttgactt gcgagctttt cgggcgtaag cttgaaaatg tgagattagg atttgggatg 30540 ccattggatc ccagaatctt cgagttgcct ttaatagtct tcgataaaga gggactagag 30600 tcgagcactg cctgtccttt ggttgaggta agtgtaaacg agagtcataa gttaccaggc 30660 tacctaaaat gttcgaaagt ggatgaacaa gatcatttgg agcttggaat ggtctccttt 30720 tggtaactgt agaaataaat ctcatgagta aggaattttg tatgaatgaa acatgaaagt 30780 taagtgaaac aatgcaaaaa aaaaaaaaaa aaaaaaagaa aaaccaaata taaaaattaa 30840 aaccaagggc caagatgaag ggacaaagaa atgaagtatt tgataaaatc ttagagattg 30900 ttgctaaata agcaaacagt gtctttgctg taactggtga gatatgttta aaattaaatc 30960 agtgtaacgt tattacgcag aaaggcagtt cacgacgcac aataaaaagc aatatcaaaa 31020 gtgaagtttt gtacatgagt tttcgaatag ttattttttt caaaaagata atttcatttg 31080 taaaagaatg agtttttgta ctagtttttt ttttttagac ttgcgaaaat tcaagcaaat 31140 gctgtagtga tgcagaggag tatatttgaa taagagaatg gaaggaaggt tcgttagcaa 31200 atttaagaaa gtagggaatg taaacaaaat ggccgcaaaa aataaagcga attaaggaag 31260 aagccttgtt ttgaagaaac acatcgaaaa acgaaaggag ggcttttttc tgggggaaga 31320 gggtgattat gggaatcact gtgaaatgga aattcttcgg ttgggcgaag agaacaactt 31380 gatgaactgg gttagatagt gttacacata tcgtaaatgg tgaaaaaata ggaaatgtaa 31440 tagtaaagaa ggaaaatata ttatatcaat gttctaacaa gacttgaaag acccagatgt 31500 caaatttgcg gcatctgtga aattgcgcgc tttagacggt aattttttct tttccaaaac 31560 aaatttttaa aatggtttaa agtattataa aagcattttt aaggtaatga aaaaggttgc 31620 taattggttt gttatataag agtatgtcgc atttgtttac gataggagag agcgattttc 31680 cacaatggac caagcacggt aaatagcatt tggggaaagt aaggtgttat gttatttgaa 31740 gggaatcaga gacaaggcag acataaacat gcaagaagag agagagttga tgaggaaaag 31800 aaaggaaagg tgaagagaat caatcagcag caatggggtg agtgggaaaa aaagggtttg 31860 atcggatgca agtagacagc aatccaggtc aaagacaaac ctagactggt gacgagcata 31920 ccgagatagc atgtgatggc aagaaacccc gagagtgttg ttggaagacg gaccgctggt 31980 aggaaaggaa atgatgggtc atgtttaaag ggttggggag aaaattgggc aaaggattgt 32040 tttgataaga aatattttgg aaggaaaatg agatttttca tagcgatgtt tttggagttg 32100 tgacagtttc caatgatttt cgtgccattt atttacattt tacacccagg ctgcacacac 32160 acacacacac acacacacac cacaccatgc taaaggaaca aataaggaaa attagcgcgg 32220 ccgttaagct tcgttgtatg acagtttgca gagggtgggt gggacaagca gattgaattg 32280 tgaatggatg gatcgagaag gaaccagttg aaaagggaaa tagtggaaat gtagggagaa 32340 aggcataggg gagatttggc ttgttgagta cgaattcgga tggagaaatg gcaatgctgt 32400 aggagccaaa aggatcgtca acagagaggt gacatgctac tcggaggaga agagtgtaga 32460 tttacagtag gagagaagcg ggaggaggga gaatagaaga agaagagagg agaattagta 32520 attgggggat ttagtgtgtt tatttcgatt gagatgaatg tttagtggga tgaagaaagt 32580 aatgaaagga tggatgaaaa aaaaagaagc ctgtgatc 32618 //