ID SPBC17D1 standard; DNA; FUN; 20000 BP. XX AC AL031322; XX SV AL031322.1 XX DT 21-AUG-1998 (Rel. 56, Created) DT 11-FEB-2003 (Rel. 74, Last updated, Version 3) XX DE S.pombe chromosome II cosmid c17D1. XX KW atp-dependent rna helicase; conserved hypothetical; KW diphthamide biosynthesis protein. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-20000 RA Wood V., Rajandream M.A., Barrell B.G., Beck A., Reinhardt R; RT ; RL Submitted (20-AUG-1998) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and Max Planck Institut fuer Molekulare Genetik, RL Ihnestr. 73, D-14195 Berlin, Germany XX DR GOA; Q10200; Q10200. DR GOA; Q10202; Q10202. DR GOA; Q10205; Q10205. DR SWISS-PROT; Q10200; YBY1_SCHPO. DR SWISS-PROT; Q10201; YBX7_SCHPO. DR SWISS-PROT; Q10202; YBX6_SCHPO. DR SWISS-PROT; Q10203; YBX5_SCHPO. DR SWISS-PROT; Q10204; YBX4_SCHPO. DR SWISS-PROT; Q10205; RR43_SCHPO. DR SWISS-PROT; Q10206; YBX2_SCHPO. DR SWISS-PROT; Q10207; YBX1_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 80% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c17D1 overlaps cosmid c17D11 and cosmid c11D11. XX FH Key Location/Qualifiers FH FT source 1..20000 FT /chromosome="II" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c17D1" FT /map="IIR" FT misc_feature 1..2571 FT /note="nominal overlap with cosmid SPBC17D11, EM:AL031739 FT S. pombe chromosome 2" FT CDS join(431..485,533..915,1036..2352) FT /db_xref="SWISS-PROT:Q10207" FT /gene="SPBC17D1.01" FT /gene="SPBC17D11.09" FT /product="hypothetical protein; sequence orphan" FT /protein_id="CAA20425.1" FT /translation="MKAVYLDYLLRIRYTYVFNLKVSYQSERRTYGATEHFVGCLVPKA FT WNCLADDYTDIKTLLDLLFGVTAVIIFACTFKCFTMTEDGLTKLNLEAFLGVSGNTQEL FT LESLGISAIPDLSNLGASNNNNSGLTFDPNDPSAAAFYIAQQVAAIEHPPPRKMTSSEK FT TRSENRERKKRWREQNEERNKDNDLRCRVNKKAKKLFGSEPSIEKTNWIEAEFTRRHTK FT RKEKERACLSQNQSSNASRANSQSLLPDLDLLATNSSANAVLQGSAINNALNALAKDPN FT LIHSLLTQIDFDPSKSKDGLNLGSLTDVVPPQPPQPEHELAALQEHNEAHDAAMRQYEL FT ERQQNAMLPGLASIDGLQALPHLDFSDSAVTNQSHSQSQNSLHPLISQSETHSIFSALS FT ETPTPVSGNGNVADAPPDFSLSQVMPLDLIAPSMQPSAVSSPMSESHVQISSEMPRTGM FT SALPMRPRSQNVDKHRKFPYYNKRNAVTTPSSPYDGAQSGSPQFPPFELPPHNYSQAQS FT PNLATPSPSFSSLPDVSLPPIVKPNLMSEPTPTNSDEKSHALGFPPPPGQKIEFQRSSS FT KNGTAKSD" FT misc_feature 486..491 FT /note="gtgaat, splice donor sequence" FT misc_feature 517..532 FT /note="ttaacgattcatgcag, splice branch and acceptor" FT misc_feature 916..921 FT /note="gtatga, splice donor sequence" FT misc_feature 1019..1035 FT /note="ctgactattatatgaag, splice branch and acceptor" FT CDS join(3258..3416,3489..3679,3728..4406,4453..4935) FT /db_xref="SWISS-PROT:Q10206" FT /gene="SPBC17D1.02" FT /product="putative diphthamide biosynthesis protein; FT similar to S. cerevisiae YIL103W" FT /protein_id="CAA20426.1" FT /translation="MSFELSAPVPLSDNSEAILEKEIGETVKIEGDLVEVYEINRTVDF FT IKSGNYNSVALQFPDEHLADSGKVASILTNLVEANVQILADTNYGSCCVDEVAAEHMSA FT DAIVHYGRACLSPTSRLPVLYVFGRLPINLHKLEKCLTIPLDQNILLVSDTRWYYAQDS FT ILKSLKTLGYQNVYESHLKERIEPNLEEASTSYTIPGRTYSLPKSLSLQDMTLLYIGPD FT SPTLSSILMSHYSLVNQFLSFDPLSNKIVEESSFTGAKLRRRYALVQRCRDAGVIGIVI FT GTLGVHRYLHVLNQLRKMILNAGKKPYMLAVGKLNPAKLANFQEIECFVLIACGENSLI FT DSKEFYRPIVTPFELVKALSSDMSWNNDFILSFDEVLKLSEGKQSKEPSEVLTEESAEP FT HFSLITGKFVNSTPMRHLDVTLETADAKNNDSSSASIEKRGMRSLAVNGVYSPAAAFLQ FT SKSWSGLDSVDEGEGPSKLYEGQSGIAKGYVGEGSKEKIQRDFGK" FT misc_feature 3417..3422 FT /note="gtatgt, splice donor sequence" FT misc_feature 3473..3488 FT /note="ttaactatttttacag, splice branch and acceptor" FT misc_feature join(3501..3679,3728..4406,4453..4551) FT /note="Match to Diphthamide_syn, Score 553.11" FT misc_feature 3680..3685 FT /note="gtaagt, splice donor sequence" FT misc_feature 3708..3727 FT /note="ctaacagataatattattag, splice branch and acceptor" FT misc_feature 4407..4412 FT /note="gtatgt, splice donor sequence" FT misc_feature 4434..4452 FT /note="ctgacaattgattttttag, splice branch and acceptor" FT 3'UTR complement(5121..5191) FT /note="mRNA from AU007862" FT CDS join(complement(6165..6208),complement(5731..6066), FT complement(5192..5624)) FT /db_xref="GOA:Q10205" FT /db_xref="SWISS-PROT:Q10205" FT /gene="SPBC17D1.03c" FT /product="putative exosome 3' 5' exoribonuclease complex; FT required for 3' processing of ribosomal 5.8S rRNA, snoRNAs FT and U4 snRNA; similar to S. cerevisiae RRP43" FT /protein_id="CAA20427.1" FT /translation="MKTVSGVKQLSFTPSIFKKITPEQYLSHLLNQDVRSDGRSVSEFR FT EIVINDNCISTANGSAIIRAGENVFVCGIKAEIAEPFENSPNEGWIVPNLELSPLCSSK FT FKPGPPSDLAQVVSQELHQTLQQSNLINLQSLCIFEKKAAWVLYADIICLNYDGSAFDY FT AWAALFAALKTVKLPTAVWDEDLERVICASTLTRPVQLSTEVRSFSWSVFDDKLLADPT FT DEEEDLSTEFLTIMLNSSKNIVKIIKLGGTHIQPLLLKKCIEVARSKF" FT misc_feature join(complement(5731..6008),complement(5198..5624)) FT /note="Match to PF01138 RNase_PH, 3' exoribonuclease family FT Score 248.65" FT misc_feature complement(5625..5640) FT /note="ctaacaacttatacag, splice branch and acceptor" FT misc_feature complement(5725..5730) FT /note="gtatgt, splice donor sequence" FT misc_feature complement(6067..6085) FT /note="ctaacattttactggatag, splice branch and acceptor" FT misc_feature complement(6159..6164) FT /note="gtaagt, splice donor sequence" FT CDS 7042..7794 FT /db_xref="SWISS-PROT:Q10204" FT /gene="SPBC17D1.04" FT /product="hypothetical protein; sequence orphan" FT /protein_id="CAA20428.1" FT /translation="MNDSEEELEQQGSQEDISSSQDTSDEKEMRKQDALYAQLIEYREI FT VSELRRSEMKNLCIQLYCSYKAGITRRNELQSDLDGYERRIPPRLRAVWPTIHSIPDES FT FFDGTSASRFRQEAAYLAVRLASKKLHKLGRMASSEELPNPDGLRYLVERLQIKLERLF FT DSVDTFRQEQGSKSMQSRVKPMDWKILYGLARVTNGSFSSSQKADVLALGNGTRACQSL FT FKEMSLQPSIDIEKVSHSNPEISIEFED" FT CDS 8549..9655 FT /db_xref="SWISS-PROT:Q10203" FT /gene="SPBC17D1.05" FT /product="hypothetical protein; serine-rich protein; FT sequence orphan" FT /protein_id="CAA20429.1" FT /translation="MSFVDGVNSWFSAASYWDGLGPTNVVQPEDDLAFVSQFEEVESAY FT DNLVKNGMIAPRRKNSFASSVNNPFSTSALSEALNGSVSMSHVPSSGLLKSTLSSTPTA FT GSNLLGTSPAEPASGLVGSSGFGSSMLGSSLPGNATSNFGSQASTSLLHPRRSTTSLLS FT SSAHHSRSSYYDLATPTRSSFSYNTVGAASLPSGGLSNLSSSLRSSSKSAGFSLFESAS FT NSFTPSSFIESANMESLSIPSRRRPSSIAPIGTRPSRKEIAFSNSSTPTDQTLRPPNPP FT AANGNATPVTAVNNVSAVADSPQSTGSSVSSSLPTLSLDFKQEYSGNNHDMSGLSSSLS FT KSHNSTSALSSQIWSSPCASTLGGVNVW" FT misc_RNA 10116..10576 FT /note="mRNA from AU006802; not associated with an ORF; FT possible 3' UTR of SPBC17D1.05" FT CDS 12043..13779 FT /db_xref="GOA:Q10202" FT /db_xref="SWISS-PROT:Q10202" FT /note="N-terminal may need truncating" FT /note="used to have code SPCC17D1.06 (typo)" FT /gene="SPBC17D1.06" FT /product="putative ATP-dependent RNA helicase; similar to FT S. cerevisiae DBP3" FT /protein_id="CAA20430.1" FT /translation="MQFCFRILILYISLSIDNNYLVTTLISLKENVFLHIFTLTFLFKA FT FLLKMAKRSVEELKRSADEEASVKRKEKKSKHEHKKHKKDKPSADKDRISKKDKKKSKK FT GKSKTKEESIEINAEEGAKIAQPAIGSANASNHNDEEAYDRYIKKHNISFADPKSSENL FT LPILQFDELDVSAKLREGLKNYKEPTPIQAATWPYLLAGRDVVGIAETGSGKTVAFGIP FT ALQYLNGLSDNKSVPRVLVVSPTRELAIQTYENLNSLIQGTNLKAVVVYGGAPKSEQAR FT AAKNASVIIGTPGRLLDLINDGSIDCSQVGYLVLDEADRMLDTGFEQDIRNIISHTPDP FT TRNGSRQTVFFSATWPESVRALAATFLKDPVKITIGSDELAASQNITQIVEILDDPRSK FT ERMLDNLLRKHLSSGGKDDKILIFVLYKKEAARVEGTLARKYNVVGIHGDMSQGARLQA FT LNDFKSGKCPVLVATDVAARGLDIPKVQLVINVTFPLTIEDYVHRIGRTGRANTKGTAI FT TFFTPQDKSHAGELVNVLRQAKQDIPEGLFKFGTAVKPKLNAYGSRVVDVPVKAATKIV FT FD" FT misc_feature 12589..13209 FT /note="Match to PF00270 DEAD, DEAD/DEAH box helicase Score FT 218.62" FT misc_feature 13333..13575 FT /note="Pfam match to entry PF00271 helicase_C, Helicases co FT nserved C-terminal domain" FT misc_feature 13336..13575 FT /note="Match to PF00271 helicase_C, Helicases conserved FT C-terminal domain Score 121.16" FT CDS join(complement(17143..17357),complement(16891..17098), FT complement(15711..16847),complement(15431..15665), FT complement(14927..15389),complement(14425..14880), FT complement(14164..14338)) FT /db_xref="SWISS-PROT:Q10201" FT /gene="SPBC17D1.07c" FT /product="calcium binding protein; calponin homology (CH) FT domain; IQ domain" FT /protein_id="CAA20431.1" FT /translation="MKMLQNKGPLQELTLNAMAPNGIFQDEPMIQKFENHYVFKKDMKS FT KRNKEVKNQMNDWLAYGYLCSVHEAKKWLEEETNNEYQNLDDFVDALVNGKVLCQLAFK FT YYPKLASNWKPRYQISERNTVYLNAFFHFLDFIGMFTPFRFETKDLVRRFNIPKVIYCL FT HALSYLLDFLEVTRHVPSLYGKLRIKKSQLNTATKEISLLKKAKKFPNFPKLKNFFCSY FT SHRHETATSNKQVSCFREVPAWIKQCQSQCRGFLTRKCVSIEKLRRDDMSERLGWLPKL FT ETKLSSISDEERLILLKESHQIYRKMVSLHLELLHLPQLEMSLDFCGFSSDDSSIAISS FT QLVPPILNNLIFKLEESPQIWILIISRFSSDGIDKIDVQNFILLILKFFGFAISASDRR FT SFLNLIMSCVMVSIQQSSAEVGHSTSDSLISWASRLFTKGFWYAISFGVFSNCFSLQLQ FT SFFEKHLGNVVDKFFLEHLCETTIESDAMRVVTEMLVSCYENRERIPNELPMVLKQIYY FT SRSESFKPSAIKEFIEYFLCDQLMNCLSVYYSKYFEGKDSKKFTLVKHFMNSLFGRVKL FT NEQTEIIWHTRNYRIVEALVRKLIHLSTPKIIPVYGGRTLSCTHKDIFDLQNILRYCDE FT RGDFSSFPSFKKLISLLGSPKLFKKHENQILLLESKNEVIHSSLPCSKSSLYQLSLSLC FT IPLIEGHLRNSLEEILFGVPTELENQKFMSVLRNDKLIKSIHPGSLSGISNSFVNSKHP FT IEQWQSRLRKILHLFSGRNEDIASLQCVLQFGSSERIHLEDIQNSHRYLCSLKKNNSQK FT DIHRNPLLSHVFDTNTKSFDTLKTLNYKHAILKKSMGELYKMEMIHECPRQLFGQILVV FT YLNRERTLLNFYLIENSKTIDEATLQLTDLIQAIKTGIYYLRMFNLPFHVKQLYTWLAP FT ISKYDSEISFNQKKERRKTFLSFERRGKNRKF" FT misc_feature complement(14339..14353) FT /note="ctaatcaaaaattag, splice branch and acceptor" FT misc_feature complement(14419..14424) FT /note="gtaagt, splice donor sequence" FT misc_feature 14571 FT /note="real end of cosmid c17D11" FT misc_feature complement(14881..14897) FT /note="ctgatctttatattcag, splice branch and acceptor" FT misc_feature complement(14921..14926) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(15390..15404) FT /note="ctaacgaatgcaaag, splice branch and acceptor" FT misc_feature complement(15425..15430) FT /note="gtacgt, splice donor sequence" FT misc_feature complement(15666..15682) FT /note="ctaaccgattgatctag, splice branch and acceptor" FT misc_feature complement(15705..15710) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(16848..16860) FT /note="ctaacgttatcag, splice branch and acceptor" FT misc_feature complement(16885..16890) FT /note="gtatgt, splice donor sequence" FT misc_feature complement(17099..17112) FT /note="ctgacattaaaaag, splice branch and acceptor" FT misc_feature complement(17137..17142) FT /note="gtaagt, splice donor sequence" FT CDS join(18052..18115,18169..18227,18272..18970,19018..19196, FT 19247..19727) FT /db_xref="GOA:Q10200" FT /db_xref="SWISS-PROT:Q10200" FT /note="first two predicted exons are tentative - may use FT internall Met at base position. 18530" FT /gene="SPBC17D1.08" FT /gene="SPBC11C11.01" FT /product="hypothetical protein; rrm RNA recognition motif; FT no apparent S. cerevisiae ortholog" FT /protein_id="CAA20432.1" FT /translation="MKKNNERVNTNPSLISKSYNMKKRPVIGTRRHFARKEIESDSDDE FT DDIFLAGERKKYLQNQSYERRKQKYVWSFNNITKSVIRNEHGNNLTLQEELLRHEAYEK FT NEEIANENDVDQGMFIQQNNILNMLVNLMKYFVHMDNISPVTTNGSLKESLRKYSSIIA FT VNIFSETGDLKKGIAIFQDLSDAEQAVQYLSNCKIDGRLISATITNHPKRLPNAEHLES FT STKTKDESQDKDKLTKLDRAKLEWLIQGLNCEKGSIGNLLCFAVEHVNNHVEITDAFLK FT EFFNDQPTDDTKVYDDDYINERGEKKLSLIYLMNDILFNGISGTSLVWRYRFSFEPHVE FT RLLDDLYLFSKRLGGRIKEDIFCKKVVKVIEVWKTWIAFQEETLERAWRNFSGNTPQSP FT QINSAALKVETKNSWTAISEETEGLQDDEEYNGIPVDVNELLNVEFISQIPMSTETSSS FT SSPQPTEERKAKFKPSFTQGTFVSKRMRMHAEDLF" FT misc_feature 18116..18121 FT /note="gtatgt, splice donor sequence" FT misc_feature 18153..18168 FT /note="tcaatttag, splice branch and acceptor" FT misc_feature 18228..18233 FT /note="gtatga, splice donor sequence" FT misc_feature 18232..20000 FT /note="nominal overlap with cosmid SPBC11C11, EM:AL031528 FT S. pombe chromosome 2" FT misc_feature 18259..18271 FT /note="ctaatgtgttcag, splice branch and acceptor" FT misc_feature 18971..18976 FT /note="gtattt, splice donor sequence" FT misc_feature 19002..19017 FT /note="ctaatgtttattgtag, splice branch and acceptor" FT misc_feature 19197..19202 FT /note="gtatgg, splice donor sequence" FT misc_feature 19232..19246 FT /note="ttaattgcgtatcag, splice branch and acceptor" XX SQ Sequence 20000 BP; 6465 A; 3383 C; 3629 G; 6523 T; 0 other; gatcataaca gctaagaact gcagtgcagt atgaattcgt taagaagcag tcaagaattc 60 agtcacagaa gactgctttg tgacgttgct ttaatactta taaaacggaa ctttggtata 120 cagctgggca agactctgtt tacaaaatct atagtcatgt ttccgataaa taaaaacgcg 180 taattcctga tttacgcgat gttcaaatcc taactgaagt ctccacgcgt atctttaatt 240 atgtaaatgg tacatatatt agcacactgt atgtgcaaat gaagataata aacagtattt 300 tgttactgaa caatcctaaa tcgtgcaaac ctccagcagt cttttctaaa tgaggaaaga 360 ataagggact atggtttata gcggcgaatt atgatttatt ctagtactta atgtccgctt 420 ggatgaaaga atgaaagctg tatatttgga ctatttgttg cgcattcgtt acacatatgt 480 ttttagtgaa tctacgttac gttctggtag acgagtttaa cgattcatgc agacctgaag 540 gtttcttatc aaagtgaacg gagaacatat ggagctacgg agcacttcgt tggatgtttg 600 gtgcccaagg cttggaactg cctggctgat gactacaccg acatcaaaac tttactcgat 660 ttgctgtttg gtgtaacggc agtaataata tttgcatgca cttttaagtg ttttacaatg 720 acggaagatg gattgacaaa gttgaacctg gaggcctttt taggggtttc ggggaatacc 780 caggaacttc tggaatcatt ggggatttca gctattcctg acttgtcaaa tcttggcgca 840 tcaaacaata ataattctgg acttacattt gatccaaatg acccttctgc ggctgctttt 900 tatatcgctc aacaggtatg atactatctt aaccaagttg gtagaactag taaatgatcc 960 gtttgatgta tagttataat aaatttattt ttatttttat ttatttaatg aaacttttct 1020 gactattata tgaaggttgc cgctattgaa caccctcctc cgaggaaaat gacctcctct 1080 gaaaaaactc gatccgaaaa tcgagagcgc aaaaaacgtt ggagagaaca aaatgaggag 1140 agaaacaaag acaacgattt acgttgtaga gttaacaaaa aggctaaaaa actttttggt 1200 agcgaaccta gcattgagaa aactaactgg attgaagctg aatttactcg tcgtcataca 1260 aaacggaaag aaaaagagcg tgcttgtttg tcccaaaatc agtcgagtaa tgcttcccgc 1320 gcgaattctc aatcactatt acctgatttg gacttgctag cgacaaattc atcagcaaat 1380 gctgttttac aaggttccgc tatcaacaat gcacttaatg ctcttgctaa agaccctaat 1440 ttaattcata gcttattgac tcaaatcgat tttgatccct ctaaaagtaa agatggtttg 1500 aatttaggct cgcttactga cgttgtgcct cctcaacctc ctcaacctga acacgaattg 1560 gccgctttgc aggaacataa tgaagcacat gatgcagcta tgcggcagta cgaattggag 1620 cgtcaacaga atgcaatgct tccgggactg gcttccatag acggattaca agctttgcct 1680 caccttgatt tttctgattc tgctgttaca aaccaatccc attcacaatc acagaactcc 1740 ctgcatccat tgatttcaca gtctgaaaca cattcgattt tttcagcttt gtcagaaaca 1800 cctaccccag tcagcggaaa tggtaatgtt gcggatgctc ctccggattt ttcactttct 1860 caagtgatgc ctttagattt aatagcacct tctatgcaac catcagctgt ttcatctcct 1920 atgtcagaat cacatgttca gatttcatct gaaatgcctc ggactggtat gtctgcatta 1980 cctatgcgtc ctcgttcgca aaatgtagac aagcatcgaa agtttcctta ttacaataaa 2040 agaaatgctg tcaccacacc ctcttctcct tatgatggcg cccaatcggg atctcctcaa 2100 tttccaccct tcgaacttcc tcctcacaat tatagccaag cccaatctcc caacttggca 2160 acaccgtctc cttcattttc ttctttacca gatgttagtc tacctccaat agtgaaacca 2220 aatttaatgt cggaacccac tcctactaat tctgatgaga aatcacatgc tttggggttc 2280 cctcctcctc ctggtcaaaa aattgagttt caacgatctt caagtaaaaa tggcactgct 2340 aaaagtgatt aatatagata tatatatata tttatattta tatttcgttc gtctaagcat 2400 tggtgtattt gtgatatttt tgtttcgatt aatgttgagg tgactactat aaaatggtgg 2460 tttgtcaaaa atcgttacag cctttgtcct ttgttttgta tacttgctat taaagcaggt 2520 aataccgaag gtttcttttg tttattaaac tatattgttt ctttagcttt tcatgtttca 2580 ctaatcgtct tatcagatgt aattttctgt taaacatttg ttctttcttt ttttctgaaa 2640 aagattgaga acgattatga gattttttga gggttttaag aagcaaaaag ctactttatt 2700 aaaaaaatta gagcatgttc tgcattttga ttgatacatt ttttatgcga ttgcgtgttt 2760 gtccttagtg gtatcaataa gtgttttgaa aattcctata cggttctttt gagtttcgtt 2820 cgtatatttg tcctacaact tcgacggtat actttatctt tcttttacgt tttgttgaat 2880 agtaaattac cgcatcagcg atgcatattt ttagttcttc ggccttgtca tttcgctgaa 2940 atgttcattc atatattagt taattctttg tttaatttat tcattgatta cttatacaat 3000 tatttgagta tatatgctca ctgcagatgt aatatttcga ccattgggaa caacacttgt 3060 aatcttaatc gtcaaacagt atagtcggta aaggcacttt ttcatactat ttatttatca 3120 gtaagggtat caaaagtaat tataatccaa tattgcttat catccaacta ttggtatctt 3180 ttaatacatt tctcagcaaa cttttttttg cgcagaacca agtggaggca acaattataa 3240 attttcgcgt ctataatatg tcttttgaat tatcagctcc agtaccttta agtgataatt 3300 cagaagcaat tctagaaaaa gaaattggcg aaaccgttaa aattgaagga gatttggttg 3360 aagtgtatga aataaatcga actgttgatt ttattaaatc tggaaattat aactcggtat 3420 gttttttttt ttttttggaa aaatttatac aattgacata gcgatttgac tattaactat 3480 ttttacaggt tgctcttcaa tttcctgatg aacacctagc cgattctgga aaagtggctt 3540 ctatcctcac gaatttagtt gaagcaaacg ttcagatttt agcagacaca aattatggta 3600 gctgttgtgt tgatgaggta gctgctgagc atatgtctgc agatgctatc gttcattatg 3660 gaagagcgtg tttatcgccg taagttaatc tttgcaattt tgtgttgcta acagataata 3720 ttattaggac ctctcgactt cctgtccttt atgtttttgg aagattacct attaatcttc 3780 ataaattgga aaaatgctta acgatacctt tggatcaaaa tattttactt gttagtgaca 3840 ctcgttggta ttatgcgcaa gactcaatcc ttaagtcctt gaaaactctt ggctaccaaa 3900 atgtatatga atcacacctt aaagagagaa ttgagccgaa cttagaagag gcatctactt 3960 cctatactat tcctggcaga acttattcgt taccgaagtc gctgtctttg caagatatga 4020 ctttgcttta tattggacca gattctccaa ctttgtcttc aattcttatg tctcattatt 4080 ctttggttaa tcagtttttg tcctttgatc cattgtcgaa taaaatagtt gaagaatcat 4140 ctttcacggg tgctaagctt cgacgaaggt atgccttggt tcaaagatgt cgagatgcag 4200 gagtcattgg aattgttata ggtactttag gagtacatcg atatttacat gttttgaatc 4260 aacttagaaa aatgatttta aatgctggaa agaagcctta tatgcttgca gttggcaaat 4320 tgaatcctgc gaaactcgca aattttcaag aaattgaatg cttcgtattg atagcatgtg 4380 gagaaaacag tttaatagac agcaaggtat gtaattatgt tggctgtttt ttactgacaa 4440 ttgatttttt aggaatttta ccggcctatt gtaacgccat ttgagttagt aaaagcattg 4500 tcgtcggata tgtcttggaa caacgatttt attttgtcgt ttgatgaagt actaaagtta 4560 tctgaaggca aacaatcaaa agaaccaagt gaagtcttga ctgaagaaag tgcagagcca 4620 cactttagtc tgattactgg aaagtttgtg aattcaaccc cgatgcgaca tttagacgtt 4680 actcttgaga ctgccgatgc aaagaataat gactcgtcct cagcctctat agaaaagcgt 4740 ggcatgagaa gtcttgcagt gaacggggtt tactctccag cagcggcgtt tcttcagtca 4800 aaatcttggt cgggacttga cagtgtagat gaaggagaag gtcctagtaa attatacgaa 4860 ggacagagtg gcatcgccaa aggatatgtt ggtgaaggca gcaaagaaaa gattcaacgt 4920 gattttggta aataaatcgg gtattgagtt gatcattctt cctatgcttg tgttttagag 4980 tttgacaaaa aaaagtttac tggttaaagg agataaacag ggttcataag ttatataaaa 5040 aaaatttcct acagcatttg aaaatcaatt agctttatga ctatagtatt ttatattaca 5100 gcaagatcaa tattacgttt caagcattaa aaacgaactt gaatattttc aaactttcaa 5160 aatttataca ccttgataac ccaaaaattt gttagaactt agaccttgca acctcaatac 5220 acttttttaa taaaaggggt tgaatgtgag tgcctccaag ctttattatc ttaacaatat 5280 ttttggagct attaagcata attgtcaaaa attcagttga aaggtcctcc tcctcgtctg 5340 tagggtcggc taacaacttg tcgtcaaata ctgaccatga gaaagaacga acttcagtac 5400 ttaattgaac tggtcttgta agggtagaag cacagataac cctctctaaa tcttcatccc 5460 aaacagcagt tggtaattta acagttttta aagcggcaaa caaagctgcc catgcataat 5520 cgaaggcact tccatcataa tttaaacaaa taatatcagc atacaatacc caggctgctt 5580 ttttttcaaa aatgcatagg gactgtaaat taatcaagtt agatctgtat aagttgttag 5640 taaaagtaac taaatattct aaatgatagt ttaacaataa atgaaacgta tggtagaaaa 5700 ttagaaaaat tccaataatt tgatacatac tgttgcaaag tctgatgcaa ttcctgcgag 5760 acaacttgcg ccaagtcaga aggagggcca ggtttaaatt tgctactgca aagaggtgat 5820 aattcaagat tgggaacaat ccaaccttca ttgggagagt tttcaaaagg ttcagcaatt 5880 tctgctttta ttccacacac aaagacattt tcgccagctc gaatgatagc actaccatta 5940 gcagtagata tgcaattatc attaattaca atttctctga attctgatac agaccgccca 6000 tctgatcgaa catcctgatt aagaagatgt gataaatact gctcaggcgt gattttctta 6060 aaaattctat ccagtaaaat gttagtactg taacaaagaa aaacaaagtg aaaaggaaac 6120 agagcactaa aaaagataga ataagaaatc aaagagcaac ttacgaaggt gtaaatgaaa 6180 gctgttttac ccccgaaaca gttttcatga tgtgaaaaga atgtagtgtt tcaataacga 6240 agctaaatga tatagtaacg tagaaagacc aaataactga agaacgatac tgaaaaatat 6300 ataaaatgaa tatgaatcac aagaattcga tatatgtgct gaattttgtc tacaggttga 6360 aattatgaaa tggagtagag ggatgaaata ggtgtacgaa gtaaagtatg aaaaacttat 6420 atggtaaata aaaggtttgt gaggtcctta aaatgtttaa attccttggt ttttttttaa 6480 tttattgaag gtatattcgg tgcaaatttc aattaaggat tgataattca tttgaatttt 6540 agctacaaaa tcccaattcg tttaaacgat tttgaaaaaa gagatcacat aattaacatt 6600 taaaaatgct aattcgaaaa aaatttattt aaggcctttt ctactgattt tttttttttt 6660 aaaaaaaggt aaaataacaa aatttacaat gatccatggt taaagaaaat aaggcataat 6720 taaacaatta aaagtcagca gaatacatac ggaatttggt aagtagcata atatatagct 6780 cttaaattaa agtaagttat ttgggtgcat gtttatattt caaaatttgc acactcttag 6840 tttatcggtt gttagacgaa gcaaaagtct tatattaata aaaaaaagga aaagtttttt 6900 tctattagat tatagttaaa ggaaattaaa aaaaaaagtc agtaaacaca cttaatatcg 6960 cgccaggtac aatgaccttt ccttaacctc tagcctacga acacaacagc cggatgctaa 7020 accttctgag gaaatgatgc tatgaatgat tctgaggaag aattagagca gcaaggaagt 7080 caagaggata tttcctcttc tcaggatact tcggatgaaa aagaaatgcg aaagcaagat 7140 gctctatacg cacagctaat agagtatcga gaaattgttt ccgaactgag aagatctgag 7200 atgaaaaatt tgtgtattca actttattgc agttataaag ctggtataac tcgtcgaaat 7260 gaattgcaaa gcgatttgga cggttatgaa cgaaggattc caccacgtct acgtgcagta 7320 tggcctacaa ttcattccat ccccgatgaa tcattttttg atggaacctc ggcttcgagg 7380 tttcgccaag aggctgcata tttggctgtg cgtttagcat caaaaaaatt acacaagttg 7440 ggtagaatgg cttcttctga ggaactgcct aatccggatg gcctccgata cttggttgaa 7500 aggttacaga taaaattgga acgccttttt gattcggttg atacttttcg acaagaacag 7560 ggaagcaaaa gcatgcaatc acgtgtaaag cctatggatt ggaagattct ttacggactt 7620 gctcgagtca caaacggttc gttttcctcg tcgcaaaaag cagacgttct tgcattgggc 7680 aatggtacaa gagcttgtca atcattattc aaagagatgt cgttacaacc tagtattgat 7740 attgaaaaag tttcacactc taacccagaa atctcgatag aatttgagga ttaagaaatt 7800 ggtgggaaat ttaataagta tgagtatttt gaaaaaaaac acgcatctgt gaacaggtca 7860 atctgcgtaa gtctcaacaa ttaatgttcc agtaaacatc ttttggctga tgtatatgtt 7920 taattatttg tgtaactccc gccgtatttg cacatatagt ttttctgcat ccgaatttct 7980 tttctttttt tttaagttat tttgtttttg cgttgatcta ggaaaaaggt tctacgcaac 8040 aagaatattg tttcaacttt atcatgctta caagttcatc ctacacttta aactggaagt 8100 ggcaagtatt tgctgaggtt aaatctttac tgttatgata ctgttttcca atatatctaa 8160 gttacacagt tttactaaat tgtataagct atttaacagt ctatgcaaag ctgatggtgt 8220 gttcgtttaa aataagggcg gcacgtggta ctgtaacttg aagtccgatg tagaaaaaat 8280 gtggagatta agtgataaca aatactacgg aaatagtaaa aaagtcatag agaagcgaag 8340 aacgaacagt tgccggatgg caacccagtt acaatagact atcgattaca aaagttagcg 8400 aaatattggg agcggctcct tggtaaacgc tgtgaaagga acctatccaa agcaaaccac 8460 aattggcagg aaattttttt tgaagtaaac aacgtttggt taaaactttg aaaataggcc 8520 aatttcaaaa aaacaacgag ttgtctttat gtcgtttgta gatggagtca acagttggtt 8580 ttcggccgct tcttattggg atgggctcgg tccaacaaat gttgttcagc cagaggacga 8640 tttggctttt gtaagtcaat ttgaagaagt tgaatcggct tatgacaatc tcgtaaaaaa 8700 tggtatgatt gcacctcgtc gaaaaaatag ttttgcctcc tcagtgaaca accccttttc 8760 gacgagtgca ttgagcgaag ccttaaatgg cagtgtttca atgagtcatg ttcccagctc 8820 tggtttgtta aaaagcacac tttcgagcac ccctactgca ggctctaatc tgctgggtac 8880 gtctcctgct gaaccggcaa gtggtttggt cggttctagt ggttttggtt ccagcatgct 8940 cggaagctcg ttaccaggta atgctacttc caatttcggt tcacaagcta gtacctcatt 9000 actacatccc aggagatcca caacgtcttt gctctctagt agtgctcatc attcacgttc 9060 ttcgtattat gatcttgcta ctccgacacg ctcctccttt tcttacaata ctgtcggtgc 9120 tgctagttta ccatctggtg ggctttctaa tctctcctct tcattgcgtt cttcttcaaa 9180 atcggctggg ttttcgttgt ttgaatctgc ttcaaatagc tttacgccct cttctttcat 9240 agagtccgct aacatggaat ctttatcgat tccttctcgt cgtcgacctt catcgatagc 9300 tccgatcggt acgcgtcctt ctcgtaaaga gatcgcattc agtaatagtt ctactcctac 9360 tgaccaaacg ctgaggcctc caaatccacc ggctgccaat ggaaatgcca caccagttac 9420 agcagtgaac aatgtttctg ctgttgctga ttctccgcag tccactggct cttctgtttc 9480 ttcttcacta ccaacactaa gtttggactt caagcaagaa tacagcggga acaatcatga 9540 tatgtctgga ttgtcttcct ctctatctaa atctcataac tcaacttctg ctttaagttc 9600 tcagatttgg tcttctccct gtgccagtac tcttggaggt gtcaacgtgt ggtaattgct 9660 acattttctt gatgcggaac tttcttggac acggaatagt attttattta taggttgagc 9720 tttgaaggtt gtgatctatt actttataat tttaattctt ttgcatttgt gggcattctg 9780 ttgttttaaa gcgctcattg gaaacttatt cgaataagat aaggaaatct aatattggtg 9840 ctgatgattt ctatcctaat attgtgagca taagatattt ctttattttc taaaaatgga 9900 aaacagaaaa attgtaactt ttttgttaaa taagttgccg gcaatttttt aattcgcttt 9960 cacttttatg ttttttaaaa gtgtttcacg aattgtcgac gttgcttaaa ggtatggttt 10020 tttttcctaa gaacttttga gtgtgggaag ggtttttgct tggttgaata gtttgttttg 10080 tgagaaggtt ctggattgaa gaaaatgtca agttacttga ctattacttt cggcacatag 10140 gtttatggtg ataaatcttt gcattttctt gacaaaagag aggacagtgg ttaaaaatgg 10200 gagagttaga tatttctatt ggtatttagt ttgaactatc aaagttaggg gattcttatc 10260 gtacatgggt atactactct tgagtgcatc gcatgcttct tgtcacagca aacggcatgg 10320 tcaatcgcat ttgagtctag gttgttggtt tttatgatat tacgtctgtg cagaagtttt 10380 gtctttcaca ggccatcgtg ctctttatct ggatttattt caggggggtg aatcaacagc 10440 ataaagatgt aaatattttt ttaaaatttt aagtagccaa atttcaaaat caattttatt 10500 ttacttgata aactagattt ggttagaaat tatttttttt attaataatt tatagtattt 10560 aattcacata tataaagcaa acctggactt cattgtactc tttcatgtta attagtgatg 10620 atttaagtta atgaatagta acatttattg gccgttattt cgctcgcata aagttggtac 10680 aaattactac cgattcggaa gcgttgttcg ctatatgtga gaaatttaaa aggtgaacat 10740 tatataaaga aaattagaat acaaataata gatatggtga agattcttaa aaaaaaaaaa 10800 ttaagagtag tcagtaatcg tgaatgtagt aatgctagtt aattgacatt ctaggaggta 10860 aaaaaaaaag tatccgtctc ccatacatcc gtaactaaat tacacgagat agcaaatcta 10920 tagacaattt ggaaattgat taggttcgcc tctattgctt aaccgcgata ggcacttaac 10980 cttgttcaat taatattttt agaatatgtc tgatagtaaa ctcgagagag acaacattat 11040 tcgaacattg taaaaaactt ccaaatttat actaataaac cttacttagt taaatatcaa 11100 gccagaaaac ccatgactct tgaaattctt tagttggttt tagctaaatt aatgaaacac 11160 aaatttaatt aaaaaacata aataaatcaa ttttatactc gattacttct acttcaagta 11220 tcaggttaca cacatcgaac gcaatggcaa tcatttcaaa acagctttgt agattttaaa 11280 agattaagta gaaagtcttg cgacttctaa tcatataaat ccatacctct taattatgca 11340 atttccaatg gtaatatata ttctaatatg cagttagctt cctactccta aaagcgcttt 11400 ggacccttat gtatttcttt aaccgatgtt aataatacat tggcaatatt taatagcaga 11460 tgatcaaaaa ggattctgca tttataagtt aatccatgat acatacagac aacagtcttt 11520 tctaaaacgg aataatgggg cgcaaccatt acttcactgc ttctagctta tttctcaaaa 11580 cacaacccaa tctctgtcca atctaattat gttaataaat ttcgtaatta gtaaaaaacc 11640 aattgacagg atgcttccaa ttatttagac agataataat tttttgaaac aataaattta 11700 attaataacg aaacacactc actgcctctg tttacctagc ttgttagcgg ctttttaaaa 11760 caatatactg tggtaaagat tttaatgacc tatatataat cttattagat attcttatca 11820 caaaaagtaa ctattatcct tctagtaata taatgaaaca actacaatca aacaaaaaac 11880 agccagctgg atatattttt ttaatgaaaa tataaagaat gatttttttt aatctataat 11940 tatttaaatt ttgtgagcat tatctttcgt actacaagac caatttgtta gtaacaaaaa 12000 aaatctggga tacaatagct tacatagcgc gaaaagaacg taatgcaatt ttgttttagg 12060 attttaatat tgtatatatc gttaagcata gataacaatt acttggttac tacgttaata 12120 tctctgaagg aaaatgtttt tttgcatatt tttactctaa cctttctctt caaagctttc 12180 cttttaaaaa tggcgaaacg atcagtggaa gagttaaaaa gatcggcgga tgaagaagct 12240 tctgttaagc gaaaggagaa gaaatcaaag catgagcata agaagcataa aaaagataag 12300 ccctctgccg acaaggatag aatttcaaaa aaggataaaa agaaatcaaa gaaaggaaaa 12360 tcaaaaacta aagaagaatc gatagaaatc aatgcggaag agggagcaaa aatcgcacaa 12420 cccgcgatcg gctcagctaa cgcttctaat cataatgatg aagaagcgta tgaccgttac 12480 attaagaagc ataatatttc ttttgcggat cctaaatcct ctgaaaattt acttccaatt 12540 cttcagttcg atgaactaga cgtttcagct aagttacgcg agggtttaaa gaattataag 12600 gaacctacgc ctattcaagc tgctacttgg ccttatttac tagctgggag agacgtggta 12660 ggaattgctg aaaccggttc tggtaagact gttgcattcg gaattcctgc tttgcaatac 12720 ctcaatggtt tgtcagataa caagtctgtc cctcgtgttt tggtagttag tcctactcga 12780 gaattagcca ttcaaacgta tgaaaacctc aatagtctta ttcaaggtac caacttaaaa 12840 gctgtggttg tttatggcgg cgcccctaaa tcggagcaag cgagggctgc caagaacgcc 12900 agtgtcatta ttggtacccc tggtcgtttg ttggatctga ttaacgatgg ctcgattgat 12960 tgttctcaag ttggttacct tgttttagat gaggcagatc gtatgcttga cactggattc 13020 gaacaagata tccgtaacat catcagccat accccagatc ccactcgtaa tggatccaga 13080 caaactgtct ttttcagtgc tacttggcct gaatccgttc gcgctcttgc tgctaccttt 13140 ttaaaggatc ccgttaaaat cactattgga agtgatgaac tagctgcttc ccaaaatatc 13200 acacagattg ttgaaattct ggatgaccca agaagcaagg agagaatgct tgataatctt 13260 ctcagaaagc atctttcttc tggagggaaa gacgataaaa tcctcatatt tgttttgtac 13320 aaaaaagaag cagctagagt tgaaggtacc ttggctagga aatataacgt ggtgggcatt 13380 catggtgata tgtcccaggg agcccgatta caagcattaa atgactttaa gtctggaaaa 13440 tgtcccgtac tagtagcaac tgacgttgcc gcccgaggtt tggacattcc taaagtgcaa 13500 cttgtgatta atgttacttt ccccttgact atagaagatt atgttcatag aatcggacgt 13560 actggccgtg ccaacacaaa aggtactgct attacatttt tcactccaca agacaagtca 13620 catgctggtg agcttgttaa tgttcttcgt caagccaaac aagatattcc tgaaggacta 13680 ttcaagtttg gaacagctgt caagcccaaa cttaatgctt acggaagtcg tgtagtcgac 13740 gttcctgtaa aggctgctac taagattgtt tttgactaaa atgtcagtgg tgtatgaaac 13800 ggttgttgtt tcctaaagtc gtcgttttct tcatattcgt ttttggtgct atgaaaattt 13860 actagtattt tggtatatag aaagggtaat tcggctaggt ttttgggctt ttgaaagttt 13920 gcatttgaag ttactaattc gttctttttc atgatatatt gtgtcatggc ataatagttt 13980 aatattcaag cgaatcgcga aggaaatatt gataatgctt taaaagcaag caattgcact 14040 caatattagt ttaaacatta atattactca agcattatgg ctaatttata atgttttagt 14100 tgataaagtc atccttttat ttgtagtaga agtaaaaaaa attgacaagc aaatatagga 14160 taattaaaac ttcctgtttt tcccccttcg ctcaaagctt aggaaagttt tcctcctttc 14220 ttttttttga ttaaaactaa tttcactatc gtacttagaa attggtgcta accaagtata 14280 cagttgcttc acatgaaaag gcaggttgaa catcctcaaa taataaattc ccgtttttct 14340 aatttttgat tagtttaaaa atgtataaaa tcaaaacagt aaatctaaat tacttttaat 14400 cagtaaattg tataggtaac ttacatagct tgaatgagat ctgtcaattg caaagttgct 14460 tcatcgatgg ttttagaatt ttcaatcaga taaaagttca gaagggttcg ttccctattg 14520 agataaacta ccaagatttg accaaaaagc tgtctagggc actcgtggat catttccatt 14580 ttgtatagtt cacccatcga cttctttaag attgcatgct tgtagtttaa agtcttaaga 14640 gtgtcgaaac ttttggtatt agtatcaaaa acatgactta aaagagggtt tctgtgtatg 14700 tctttttgac tattattctt tttcaagctg cacaaatatc gatggctgtt ttgaatgtct 14760 tctaagtgaa ttcgttcact tgagccaaat tgaagaacac attgcaaaga ggctatatct 14820 tcatttcttc cggaaaaaag gtgtaatatt tttcttaatc tagactgcca ttgctcaatt 14880 ctgaatataa agatcagtaa atatcattga aaattcgacc acttacgggt gtttcgagtt 14940 aacgaaagaa tttgaaatcc ctgataaaga accaggatga atggacttga ttaatttatc 15000 attccttaaa actgacatga acttttggtt ttcgagctca gtgggtaccc cgaaaagtat 15060 ttcctccaac gaattgcgaa ggtggccttc aattagagga atacataagc ttaaggaaag 15120 ttggtataaa gaagacttag agcagggtaa agacgaatga atgacttcat tttttgactc 15180 cagaagcaaa atttgatttt catgcttttt aaacagcttc ggagatccga gtaatgatat 15240 taacttctta aaagaaggaa atgaactaaa atctccacgt tcatcacaat atcttagaat 15300 attttgaagg tcaaagatgt ctttgtgggt acaactgagt gttcttccgc cgtagactgg 15360 tataatttta ggcgttgata aatgaatcac tttgcattcg ttagctttat cttcaataat 15420 caaaacgtac attttcttac aagagcctcg acgattctat aattcctagt atgccaaatt 15480 atttcagttt gctcattaag tttaacccta ccgaatagag agttcataaa atgctttaca 15540 agagtgaatt ttttcgagtc cttcccttca aagtactttg agtagtagac tgaaaggcag 15600 ttcattagct gatcacacaa aaagtattca ataaattcct taatagctga aggcttaaaa 15660 gattcctaga tcaatcggtt agaaatcgga gtttattaca taaaacttac agatcttgaa 15720 taatatattt gttttaatac cataggaagt tcattaggga ttctttccct attttcataa 15780 cacgaaacaa gcatctctgt aacaaccctc attgcatcac tttcaattgt cgtttcacat 15840 aagtgctcca agaaaaattt atcgactaca tttcctaaat gtttttcaaa gaatgattga 15900 agctgcaaac tgaaacaatt agaaaatact ccaaatgata tagcgtacca aaatccttta 15960 gtgaacagtc ttgaggccca cgaaataaga gaatcactgg tcgaatgtcc cacttccgca 16020 gacgattgtt gaatagaaac cataacacaa gacattatca aatttagaaa acttcttcga 16080 tcagaagctg aaattgcaaa gccaaagaat tttaatatca ggagaataaa gttttgaaca 16140 tcaattttgt caatgccatc agatgagaat cttgatatta ttaatatcca aatttgagga 16200 gactcttcaa gcttaaagat caaattgttg agtatcggcg gaaccagctg actggaaatt 16260 gcaatagatg aatcgtcact actaaatcca caaaaatcaa gtgacatttc caattgcggt 16320 aaatgaagaa gctctaaatg taatgatacc atctttctgt atatttggtg gctttctttc 16380 agtagtatca atctttcctc atcagaaata gagcttagtt tagtctctag ctttggcagc 16440 caacctaatc gctcagacat atcatcgcgc cttaattttt ctatactaac acatttcctt 16500 gttaaaaaac cacgacattg ggattgacat tgtttaatcc acgctggtac ttctcgaaag 16560 caggaaactt gcttattaga agttgctgtt tcatggcgat gtgaatagga acagaaaaaa 16620 ttttttaatt tcggaaagtt tggaaatttt tttgcttttt ttaataagga aatctctttt 16680 gttgcagtgt tcagttggga ttttttaatt cgcagcttcc catataggga tggaacatga 16740 cgggtgactt caagaaaatc aagaagataa gaaagagcgt gtaagcaata gattactttt 16800 ggaatattaa atcttctaac taaatctttc gtctcgaagc gaaatggctg ataacgttag 16860 tacatggata taattataac ataaacatac agtaaacatt ccaatgaaat ctaaaaaatg 16920 gaagaatgca tttaagtaaa ccgtattcct ttcagatatt tgataacgtg gcttccaatt 16980 tgaagctaac ttgggataat atttaaaagc taactgacac agaactttac catttacaag 17040 tgcatcaaca aagtcatcaa ggttctgata ttcgttatta gtttcctctt caagccatct 17100 ttttaatgtc agtgtcaatt ccgattgtta gaatagactt actttttagc ttcatgaacg 17160 ctacaaagat agccataggc aagccagtca ttcatttgat tcttaacttc tttattgcgt 17220 ttggacttca tatctttttt aaaaacatag tggttttcaa atttttgtat catcggttca 17280 tcctgaaaaa taccattcgg agccatcgca ttaagcgtaa gctcctgcaa cggcccttta 17340 ttctgtaaca ttttcattga aagtggatgc aatttgatgt tttttgcaaa atttgttctg 17400 cagaagagtg agctatatac gttattatta tggcaaactc gtatttaact atttgtaaac 17460 aaacaaacaa accaaataga acttcgagta tcaaagggtc attcttataa ttcgtaaaca 17520 gttgagagaa tttagatgag tgcgcaaata aacaaacatt tcgagttaat attaatccag 17580 ttttgagtgt aaattttttt gacctcgagt ttggaagata actctccgca ttaataatgt 17640 agacatgatt gcactgcaga tataacaatc atgtacttca ttgaaccttt aatcgttggt 17700 ttatcatgtt aacaatatct ttattcaacg agctacgtcc gtaatagaaa ttcaagatta 17760 tttggtagaa aaattaagaa tacataaaat tttatgttat tgtcatctta tacgttggaa 17820 aagtagtatt ttaaatgata catcgaccac tgtaagggaa gttgctgcat ttcgaaattt 17880 cattatatat gtgaattaat ttcctaaaat ttgttgatta taaatccagc gctgatagat 17940 ttaagaatcg atgtcttctt gttttcgtac aaatcgttgt cgttgttctg ctagcattgt 18000 gtcctaagcc taagctcatg aattttcaaa gtcaatttga ggactggagg aatgaagaaa 18060 aataatgaaa gagtaaatac aaatccatcc ttgatttcaa aatcgtacaa tatgagtatg 18120 taaatattga ttgtaaggta atttagtaat gcctaatttt caatttagag aaaaggcccg 18180 ttatcggaac gcgacgacat tttgcccgaa aagaaattga atctgatgta tgatcagttt 18240 taaataacct aatcaagtct aatgtgttca gagtgacgac gaagatgata tttttctcgc 18300 aggcgaacgt aaaaaatatc ttcaaaatca atcttacgaa aggaggaagc aaaagtacgt 18360 atggtctttt aataacatta ctaagtctgt cattagaaat gaacacggaa acaatttgac 18420 tcttcaggag gaactattaa gacatgaagc atatgaaaaa aatgaagaga tagctaatga 18480 aaatgatgtt gatcaaggta tgttcattca acagaataac attctaaata tgttagtcaa 18540 tctaatgaaa tattttgtac acatggacaa tatttcaccc gtgactacga acggttccct 18600 taaagaatcc cttcgaaagt attcatcaat tattgctgtg aatatttttt ctgaaaccgg 18660 agacttgaaa aaagggattg ctatttttca agatctttca gatgccgaac aagccgtaca 18720 gtatttgtct aattgtaaaa ttgacggtcg acttatttca gctacaatca cgaatcatcc 18780 aaaacggttg cctaacgcag agcacctaga gtcttcaacg aagacaaagg atgaatctca 18840 ggataaagat aaattgacaa aacttgacag ggcaaaattg gagtggttga tacagggatt 18900 gaattgtgaa aaaggaagta ttggaaatct actctgcttt gctgtagaac atgtcaataa 18960 ccatgtagag gtatttttgt ttcaagacta tattcgtcat gctaatgttt attgtagatt 19020 actgatgcat ttttgaaaga gttttttaac gatcagccta ctgatgatac aaaagtttac 19080 gacgatgact acataaatga aagaggtgaa aagaaattga gtttgatata tttaatgaac 19140 gacattctat ttaacggcat atcaggtact tcattagttt ggcggtaccg atttaggtat 19200 ggttttaaaa cttttactat tgaattgaaa attaattgcg tatcagtttt gaacctcatg 19260 ttgaaagatt acttgatgat ttatatcttt tcagcaagcg actaggagga agaataaaag 19320 aagatatttt ttgtaaaaaa gtagttaagg ttatagaagt ttggaagacc tggattgctt 19380 ttcaggaaga aacactggag cgtgcatgga gaaatttttc gggaaatacc cctcaatcac 19440 cacaaataaa ttctgctgct ttgaaagtgg aaacaaagaa tagctggaca gcaatttctg 19500 aagagactga aggacttcaa gatgacgaag agtataatgg tattcctgtc gatgtaaacg 19560 aattgttaaa cgtagaattc atatcgcaaa taccaatgag tacggaaaca agctccagtt 19620 caagcccgca gcctacggag gaacggaaag caaagttcaa acccagtttt actcaaggca 19680 cattcgtctc aaagcgcatg cgtatgcatg cggaggattt attctagaaa atagaagaat 19740 gcaattgata aaaaagaact acacttctac aatttagaat atcgcttttc atataaacaa 19800 ggtatgactg atgttaaatt tatccatttt taactacccg taatactatt atactttaat 19860 gacaacgatt tttgttttct ctttcatcaa gcattgtatt gaataactta tagacgaaga 19920 atgctattgc tgctgtgcaa actggcttta tcaattcgat atataaacag ttttcgccat 19980 gcatggctaa gatcgtaaag 20000 //