ID SPBC1778 standard; DNA; FUN; 19011 BP. XX AC AL049489; XX SV AL049489.1 XX DT 24-MAR-1999 (Rel. 59, Created) DT 22-MAY-2001 (Rel. 67, Last updated, Version 2) XX DE S.pombe chromosome II cosmid c1778. XX KW actin binding; actin polymerisation complex; Calponin; fimbrin; LTR; KW rad35/dfp1- like; TBC domain; zuotin-like. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-19011 RA Oliver K., Harris D., Wood V., Rajandream M.A., Barrell B.G.; RT ; RL Submitted (23-MAR-1998) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk XX DR GOA; O59945; O59945. DR GOA; Q96TL7; Q96TL7. DR GOA; Q9Y7J0; Q9Y7J0. DR GOA; Q9Y7J1; Q9Y7J1. DR GOA; Q9Y7J3; Q9Y7J3. DR GOA; Q9Y7J5; Q9Y7J5. DR SPTREMBL; O59945; O59945. DR SPTREMBL; Q9Y7I8; Q9Y7I8. DR SPTREMBL; Q9Y7J2; Q9Y7J2. DR SPTREMBL; Q9Y7J3; Q9Y7J3. DR SPTREMBL; Q9Y7J5; Q9Y7J5. DR SPTREMBL; Q9Y7J6; Q9Y7J6. DR SWISS-PROT; Q96TL7; RAP1_SCHPO. DR SWISS-PROT; Q9Y7J0; NAPY_SCHPO. DR SWISS-PROT; Q9Y7J1; SPO6_SCHPO. DR SWISS-PROT; Q9Y7J4; AR21_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c1778 is overlapped by cosmid c30D10, CC embl accession number Z97992 at the 5' end and cosmid CC c4C3 embl accession number AL021730 at the 3' end. XX FH Key Location/Qualifiers FH FT source 1..19011 FT /chromosome="II" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c1778" FT /map="IIR" FT misc_feature complement(1..108) FT /note="nominal overlap with cosmid SPBC30D10, EM:Z97992 S. FT pombe chromosome 2" FT CDS complement(1..372) FT /codon_start=1 FT /db_xref="SPTREMBL:Q9Y7I8" FT /label=SPBC1778.01c FT /note="SPBC1778.01c, len:123, SIMILARITY:Saccharomyces FT cerevisiae, ZUO1_YEAST, zuotin., (433 aa), fasta scores: FT opt: 260, E():1.7e-09, (38.8% identity in 121 aa)" FT /partial FT /gene="SPBC30D10.01" FT /gene="SPBC1778.01c" FT /product="zuotin-like protein; putative zdna binding; dna FT domain containing protein" FT /protein_id="CAB39796.1" FT /translation="MSAGDSIQLFPPTTKQAIEASFVPHGKISPLIKRAVEPVGPLFLA FT HARRQRHGRTFSEDERLEVKNKVQEEVKEESEDEEEDPAMLRADPKEWKQQDHYAVLGL FT SKYRYKADTEQIKKAHLKKV" FT CDS join(2416..2511,2558..2929,3013..4626) FT /db_xref="GOA:Q96TL7" FT /db_xref="SWISS-PROT:Q96TL7" FT /label=rap1 FT /note="SPBC1778.02, len:693" FT /note="sequence updated: 22.05.01. N terminal exon added FT Yasushi Hiraoka, pers comm" FT /gene="rap1" FT /gene="SPBC1778.02" FT /product="may be involved in telomeric and mating type FT silencing by similarity to S. cerevisiae RAP1; GFP-gene FT fusion nuclear; myb DNA binding domain" FT /protein_id="CAC39280.1" FT /translation="MSFTFTKSDGSSILFAVSKNFEHIRGFKNAIDCFKGKIEFLSFDK FT VDPTKHDYYLVAEDERVSDLDIPKGFFERNPEFRHKMLKIAWITQCIEQGKLLPTESFE FT VELNQDDVNRTHDGFRKRELFTLEDEKILIDHVHKNDINRFGTKVYEELARKYPQHSLE FT SWRQHYKYMKKRLPPVSDSDESNYCQRIIVKPYSSQKDYTQSTHEQTLSSPISKSASVS FT KSENKALVNNKRYSDSYFYFSKMRRISIDVDYVDEDLNLINAYLSQFGKKRSLNELCAL FT LSRRFSNRHTFSEWRALFMHFFPFINSEGVDPAILSDRETSAMLDETSDNEVADIDDQM FT IERKYLFSASEPNTVKSTNRLIFSERKAYAADDSIDNTPSKVPIVNSLSDPRTNRPFFY FT SNPDSMYRSISNPLHLVDSQHLSPLNRKTHFNNPIGQPQFTCLDDHEKTLRETSFRSLD FT DMSLRKSNSDNIFVKPGEDLEIPLLSDYSDSENISEKSSDDEEAFEKQVTSSYSSPIKV FT KSQGKSSKGSSGLDVREHEGSDDDAEVFVDRSPESFGATKVAHTSLEGNAASHKKVEEN FT MQQPVTKKQKKYRMVNEEAHTGPTIIIPSDNNEKVTTLPAGHVPSEEKGKFINLAMHEL FT QNEVSILRSSVNHREVDEAIDNILRYTNSTEQQFLEAMESTGGRVRIAIAKLLSKQTS" FT intron 2512..2557 FT /note="confirmed by cDNA" FT misc_feature 2930..2935 FT /note="gtatga, splice donor sequence" FT intron 2930..3012 FT /note="confirmed by cDNA" FT CDS join(complement(6184..6215),complement(4905..6003)) FT /db_xref="GOA:Q9Y7J0" FT /db_xref="SWISS-PROT:Q9Y7J0" FT /label=SPBC1778.03c FT /note="SPBC1778.03c, len:376, SIMILARITY:Saccharomyces FT cerevisiae, YGG7_YEAST, hypothetical 43.5 kd protein in FT rpb9-alg2 intergenic region., (384 aa), fasta scores: opt: FT 488, E():1.2e-25, (32.2% identity in 366 aa)" FT /gene="SPBC1778.03c" FT /product="putative NADH pyrophosphatase I of the Nudix FT family of hydrolases; by similarity to yeast nyp1" FT /protein_id="CAB39798.1" FT /translation="MQGFKIARHFELPTAPSQFFAGSSLNRLSFLRSNREFLNKAFYDH FT TTRFLPFCDLNPALLVKDDKLVTLSYPQISKYFTFSPFEHTDKQIAERFSKGESLPVLV FT YMGNEERNGPTDNWSQHNVFAIDITGIDELQQSIRDNGGTFVNLRSIFTEQYQLSASDS FT GACAFARSILDWISRYRFCPGCGKRNIPTMGGTKLVCSDVLLNDDSNCPSKKGINNYQY FT PRTDPCVIMVILSHDMQHILLGRALRHPKGLYACLAGFLEPGESLEEAVVRETYEESGV FT DVEKVLYYASQPWPFPQSLMLACFGIARKNAKIQRDKDLELEDVRFFSREEVLRSLEWD FT AKDGPAPILFPPKLSIARNLIQAFAYDDWTNSQVKM" FT misc_feature complement(5193..5315) FT /note="Match to PF00293, Bacterial mutT protein" FT misc_feature complement(6004..6018) FT /note="ctaacgtttttcaag, splice branch and acceptor" FT misc_feature complement(6178..6183) FT /note="gtaagt, splice donor sequence" FT CDS join(7334..7798,7850..7982,8029..8750,8797..8901) FT /db_xref="GOA:Q9Y7J1" FT /db_xref="SWISS-PROT:Q9Y7J1" FT /label=spo6 FT /note="SPBC1778.04, len:474, SIMILARITY:Schizosaccharomyces FT pombe, O59836, rad35 gene., (545 aa), fasta scores: opt: FT 483, E():2.7e-24, (29.6% identity in 416 aa)" FT /gene="SPBC1778.04" FT /gene="spo6" FT /product="Spo6p; similarity to S. pombe rad35/dfp1" FT /protein_id="CAB39799.1" FT /translation="MDFYSVKSQPFVRSPLVDQNPSIQNINEEVKRDIQNPLSYKTETS FT DKELCQTAACATSCSDWYPQQQTHMPHQNAFDSAKATAKMALPPTAFSNYCVKPSLTRN FT KDIPRTSIRVSKLRYWQRDYRLAFPNFIFYFDNVDEEIKRRVTQKINNLGAKVATLFTF FT EVTHFITTRTTDPEMCQPNDVLYLSKTANMKIWLLDKLLNRILFTLLNSDSLVNTSASC FT LQSLLDGEKVYGTSDKDFYVPSKNVEYFREYFLCIRDLSQYYKPIAVREWEKTLDSGEI FT LWPSLAITAQGRCPFNTGRRRELKITKHNHPAHEIRKQLLSCTNQTNQNNVVKNSASVL FT VRQIMGDYNITESAVDGAKQMPTEFPKPENLLPVEKRAAMSPLNLLEPRLINKQNTLAN FT QSPRQPPNAFDADPLAHKKVKIETKSGYCENCCERYKDLERHLGGKHHRRFAEKDENFQ FT GLDDLFLLIRRPIRTN" FT misc_feature 7799..7804 FT /note="gtaagt, splice donor sequence" FT misc_feature 7835..7849 FT /note="ctaacacatatatag, splice branch and acceptor" FT misc_feature 7983..7988 FT /note="gtaagt, splice donor sequence" FT misc_feature 8016..8028 FT /note="ctaactttcttag, splice branch and acceptor" FT misc_feature 8751..8756 FT /note="gtaagt, splice donor sequence" FT misc_feature 8782..8796 FT /note="ctaacacatcgatag, splice branch and acceptor" FT CDS complement(9166..9462) FT /db_xref="SPTREMBL:Q9Y7J2" FT /label=SPBC1778.05c FT /note="SPBC1778.05c, len:98" FT /gene="SPBC1778.05c" FT /product="very hypothetical protein" FT /protein_id="CAB39800.1" FT /translation="MYSLYTATNPSPLVAESTDDVIAHQRDVLFETIIEFERGKLLIAA FT ISIDGAEDKLYSKDPLLLGIVGTENAKEGMMQIKSELLKECITNELSTLGKPV" FT LTR complement(9873..10230) FT /note="lone tf2-type LTR" FT CDS join(complement(12558..12791),complement(10993..12481), FT complement(10817..10938)) FT /db_xref="GOA:O59945" FT /db_xref="SPTREMBL:O59945" FT /label=fim1 FT /note="SPBC1778.06c, len:614" FT /gene="SPBC1778.06c" FT /product="fimbrin" FT /gene="fim1" FT /protein_id="CAB39801.1" FT /translation="MLALKLQKKYPELTNEEILTLTDQFNKLDVDGKGYLDQPTTIKAF FT EDSKKGSYDEVREAIREVNVDSSGRVEPEDFVGIFNVLKKGVEGTEVKKGRITIKGSSS FT SVSHTINEEERREFIKHINSVLAGDPDVGSRVPINTETFEFFDQCKDGLILSKLINDSV FT PDTIDERVLNKQRNNKPLDNFKCIENNNVVINSAKAMGGISITNIGAGDILEGREHLIL FT GLVWQIIRRGLLGKIDITLHPELYRLLEEDETLDQFLRLPPEKILLRWFNYHLKAANWP FT RTVSNFSKDVSDGENYTVLLNQLAPELCSRAPLQTTDVLQRAEQVLQNAEKLDCRKYLT FT PTAMVAGNPKLNLAFVAHLFNTHPGLEPLNEEEKPEIEPFDAEGEREARVFTLWLNSLD FT VTPSIHDFFNNLRDGLILLQAYDKITPNTVNWKKVNKAPASGDEMMRFKAVENCNYAVD FT LGKNQGFSLVGIQGADITDGSRTLTLALVWQMMRMNITKTLHSLSRGGKTLSDSDMVAW FT ANSMAAKGGKGSQIRSFRDPSISTGVFVLDVLHGIKSEYVDYNLVTDGSTEELAIQNAR FT LAISIARKLGAVIFILPEDIVAVRPRLVLHFIGSLMAV" FT misc_feature join(complement(10993..11194),complement(10826..10938)) FT /note="Match to PF00307, Calponin homology (CH) domain" FT misc_feature complement(10939..10954) FT /note="ctaacacatcgtttag, splice branch and acceptor" FT misc_feature complement(10987..10992) FT /note="gtatgt, splice donor sequence" FT misc_feature complement(11231..11563) FT /note="Match to PF00307, Calponin homology (CH) domain" FT misc_feature complement(11624..11935) FT /note="Match to PF00307, Calponin homology (CH) domain" FT misc_feature complement(12017..12382) FT /note="Match to PF00307, Calponin homology (CH) domain" FT misc_feature complement(12482..12494) FT /note="ctaatgcatatag, splice branch and acceptor" FT misc_feature complement(12552..12557) FT /note="gtaagt, splice donor sequence" FT CDS join(14011..14512,14630..15249) FT /db_xref="GOA:Q9Y7J3" FT /db_xref="SPTREMBL:Q9Y7J3" FT /label=SPBC1778.07 FT /note="SPBC1778.07, len:373, SIMILARITY:Caenorhabditis FT elegans., O62483, y48e1c.2 protein., (369 aa), fasta FT scores: opt: 757, E():0, (37.6% identity in 354 aa)" FT /gene="SPBC1778.07" FT /product="putative methyltransferase; similar to S. FT cerevisiae YNL092W" FT /protein_id="CAB39802.1" FT /translation="MEYDEEEVKVLKEVLSAFFLYRQYAHTITQQKRKSMSRLSFEHKD FT LLLQDSDNNFLKHLSRIDQCIEQNSVLAEAIANAAIPVFCSDFDQNELFHVNVDMMQKV FT SSTLKQIARDWSTECVEERRTTYAPFIEELNSLFPSDSIDRSKIRVLVPGSGLGRLAFD FT IAVEGFACQGNEFSYFMLLTSHFILNCVKQENQFLVYPYIHSFSNHVMRDDQVRSLNIP FT DAVPSQYLRNSQNFSMAAGDFLEVYGTEESRDSFQVVATCFFIDTTKNILDYLDTIKNC FT LVDGGYWINLGPLLYHFESEGTSNSNSDSQQQPFVELTLEQLFYVMDSMGFEVLKHNSV FT DTTYMGDKRSMLEWIYHPHYWVCRLQKSKLRFQ" FT misc_feature 14513..14518 FT /note="gtaggt, splice donor sequence" FT misc_feature 14616..14629 FT /note="ctaacatttaatag, splice branch and acceptor" FT CDS join(complement(16249..16254),complement(16103..16202), FT complement(15747..16022),complement(15508..15650)) FT /db_xref="SWISS-PROT:Q9Y7J4" FT /label=SPBC1778.08c FT /note="SPBC1778.08c, len:174, SIMILARITY:Saccharomyces FT cerevisiae, AR21_YEAST, arp2/3 complex 21 kd subunit, (178 FT aa), fasta scores: opt: 647, E():0, (53.6% identity in 179 FT aa)" FT /gene="SPBC1778.08c" FT /product="Component of the ARP2/3 actin-organizing complex; FT involved in actin assembly and function" FT /protein_id="CAB39803.1" FT /translation="MPAYHSSFLSLTDVPTTGNIAMLPLKTKFRGPAYPADESQMDIID FT ECIGLFRANCFFRNFEIKGPADRTLIYGTLFISECLGRVNGLNYRDAERQLNSLALENF FT SIPGSAGFPLNALYAPPLSPQDAEIMRTYLTQFRQELAYRLLSHVYATEKDHPSKWWTC FT FSKRRFMNKAL" FT misc_feature complement(15651..15667) FT /note="ctaactattaaaaaaag, splice branch and acceptor" FT misc_feature complement(15741..15746) FT /note="gtaaga, splice donor sequence" FT misc_feature complement(16023..16040) FT /note="ctaacattttttatacag, splice branch and acceptor" FT misc_feature complement(16097..16102) FT /note="gtatgt, splice donor sequence" FT misc_feature complement(16203..16219) FT /note="ctgacatgttatgaaag, splice branch and acceptor" FT misc_feature complement(16243..16248) FT /note="gtatgt, splice donor sequence" FT CDS 16774..18018 FT /db_xref="GOA:Q9Y7J5" FT /db_xref="SPTREMBL:Q9Y7J5" FT /label=SPBC1778.09 FT /note="SPBC1778.09, len:414, SIMILARITY:Arabidopsis FT thaliana, O81347, plant adhesion molecule 1., (356 aa), FT fasta scores: opt: 485, E():2.2e-25, (35.8% identity in 271 FT aa)" FT /gene="SPBC1778.09" FT /product="TBC domain protein; putative GTPase activating FT protein of Rab-like GTPase" FT /protein_id="CAB39804.1" FT /translation="MENPSPTRTTNLQRIRSLYRLQEDKNNLNIPEPINGKVQEIDTKE FT SLENVDRYGNYRSDFNVNNLGFYKVSKDPTLDKPNPAKRLGNKLIGHDDMLKYVDESIF FT MVVPGESHDRNEISAKELSRIQKWKSMCSIHLVSGNQLHSFRKTRKLILRTFKGIPDCW FT RSIAWWSFLVDSLPDKKLIDKYYQLNEQICDYDVQIDLDVPRTAATHFLFRKRYIGGQR FT LLFRVLHAVALYIPRVGYVQGMASIAATLLIYYPEEQAFIMMVNLLENRGMGDLFSSGF FT DTLLKAFDMLKHELSFTQSGRHLAEIGAEPSAFATRWYLTVFHQCVPFHTQLRIWDLLF FT LLGGSKGQTVRLLQATSLAVIQGMWDTLIDADFEVVMQALSGVIPIQNDNALLARIQLF FT WEKMPSENSSKSKRN" FT misc_feature 17236..17886 FT /note="Match to PF00566, TBC domain" FT CDS complement(18511..19011) FT /codon_start=1 FT /db_xref="SPTREMBL:Q9Y7J6" FT /label=SPBC1778.10c FT /note="SPBC1778.10c, len:165, SIMILARITY: low to FT Schizosaccharomyces pombe, Q12701, protein kinase, (592 FT aa), fasta scores: opt: 134, E():0.032, (22.2% identity in FT 153 aa)" FT /partial FT /gene="SPBC1778.10c" FT /gene="SPBC4C3.11" FT /product="hypothetical protein" FT /protein_id="CAB39805.1" FT /translation="NRFTAPTAHYGYASLRSHQMPVDRLYYKLVPSSESIIESTSVFVS FT PIPSVPEGNKFPSGLSKMFLKRKQRVMLLTDVGRCAFVCKGKHERLFIEMEVNLKDSSV FT VVIFDENSSKRFLIEDKVQSWIIEDSSGDVTKYKDKILKFADVASSHQSRSSEENVEEN FT EEE" FT misc_feature complement(18904..19011) FT /note="nominal overlap with cosmid SPBC4C3, EM:AL021730 S. FT pombe chromosome 2" XX SQ Sequence 19011 BP; 6370 A; 3407 C; 3360 G; 5874 T; 0 other; aaccttcttc aaatgagctt tcttgatttg ctcagtatca gctttgtagc ggtacttgga 60 aagacctaag acagcataat gatcttgttg cttccattcc ttgggatcag cacggagcat 120 agcaggatcc tcctcttcgt cttcagattc ctccttgacc tcttcttgaa ctttgttctt 180 tacttcaagg cgctcatctt cactaaatgt acgaccatgc ctttgacgcc tagcatgggc 240 aaggaaaagt ggacctactg gttcaaccgc acgcttaatt aaagggctaa tttttccatg 300 aggaacaaaa gaagcctcaa tagcttgctt ggtagtagga gggaataact gaatcgaatc 360 accggcgctc attgcaaagg ttaggaaagg acaacttcag tagctgaaaa aatattcata 420 tagatttgac agctaaatga acttcaacgt tttctaatgt actacgttat tttacctaca 480 acatatttta ctaattattt atttcagtat ttctttaacg tacatggaaa actttgcata 540 gcttataacc aaacaacgta tttcaaaaac aagaattttc acgctattcg aattcaaaaa 600 atccagtgta caaaaggtat tcaggtttaa tgaagttcat cgagaattcg agtgaatcga 660 ttgccgctgc ttttccaaaa aatcttctcg atgaggacat gtcgattgtc acgatctaat 720 tcaaaattgt tcaatactgt taactggcta gagttttttg gaacccaaaa aatgtaattg 780 tgcaaataat tattaatgat ttttctttca aactaactaa accttttgtt tatgaaatgc 840 ttagtatcgt atttctgacg cctttaaatc ctcatttcgt agtcgctttc gcaacaactt 900 aaaatacagc tgaaaggaat attcacttaa gcaatttttg taaaagcgca agtgtgagta 960 gaacatcaga agagggaggg gggaaagaag taaatatacg atatttctat gaaagaaagt 1020 ttacagctcc acagattccc atgttatttc tattatagta ccagcgaggc cttagacgct 1080 tgactgcagt ggtcggacgg gaactagtgt ttttgtcaag gtaaacgatc attactaatt 1140 atagcaatat tcatacttat gttaaaaata taacacagtg taataaaaaa gaaaaatact 1200 agaaaataca aaatacattc attgttatac gacatgcatt ggttaagata tacttcattt 1260 caaattgcgt attttaaagt ctcatcatat catctaaatg ttatcccatt gtatgcagta 1320 tcctttaatc atcttcaaca agcagttagt tgtgtcgtaa aaaattaact ggcattaatt 1380 aaggaagcaa attgtaggta ttgtgaatat atatcattaa ttcgcatttg aatctctaat 1440 ataaataatc ttaatattta gttcagagct gttgtataat agtatattgg cgattagttt 1500 tatcggaagg aagctaaaca aaaaaaatta attaatgcaa caggtaaacg tgaaagcttt 1560 cacgaagata aacgggtaca aactttaagc caattagtac atactttttt tttattgtat 1620 tctatactaa gtatattaaa atgagatgtc agtaaatttt gttttattgt ttacatattt 1680 aattcggtta tttaatttta aataacctat ttgatgatta aaaaaatttt gcaacaataa 1740 tcgggttagt tttgaattgt aaattaaaac aaatatcagc ttagatattt taaataaagt 1800 gtcaatttct aatttctttt tttctttttt agttaatttt ttttttattt tttgaaatat 1860 atattactgc ttcgtaattg gaacttcaaa cgtttttggc taggtctttc ataacaatga 1920 tgaattctga aaaaaaaatt aaaaaaaatt aaataaatat ttaacactca tattaaaata 1980 attttattta actttctgaa tatcatttcc agtagaggcg atgttgatgc gaaatgtttt 2040 gagttatact gtttgaggac tatttgaggg tttataaatt tcggtatacg aattctcttg 2100 attaaccgat tgtaaattgc atataaaagc tattatgact aattccaaat atttaatgtt 2160 gaatgaacac taagtgttcc tagtttcgaa ttcgagaata taattctttg tcaggttatt 2220 gctttaaaag taagcttatg cttgaatata taaattataa tgcttttgcc ttctgcttat 2280 tcgcatactt tccaacgtta catggtgaac gcactacttc actccactta ctcatccagc 2340 atttcttgat tgtaaagtaa attacttatt ttttaactca tttttacgcg caaaaaaaga 2400 ataaaagtat gaactatgtc atttacattc accaaaagcg atggctcgtc cattttattt 2460 gcagtgtcaa aaaactttga acatattagg ggattcaaaa atgcaattga tgtatggatt 2520 aatcattatc aaaaaatttc taatcattat tatttagtgt tttaaaggaa aaattgaatt 2580 tttaagtttt gataaagttg accctactaa acacgattat tacttagtcg cagaagatga 2640 acgcgtctcg gacttagata ttcccaaggg atttttcgag cgtaatccag aatttcgaca 2700 taaaatgtta aaaattgcgt ggattactca gtgtattgaa caaggaaaac ttttgcctac 2760 ggaatccttc gaagtagaat taaatcaaga cgacgtaaat cgtacccatg atgggtttag 2820 aaagagagaa ctgttcactt tagaagatga aaaaattctt attgaccatg tgcataagaa 2880 tgatataaac cgctttggta caaaggttta tgaggaactc gccagaaagg tatgatcttg 2940 cttaccatta attgtttttt attttttttc taacattttc cgctttctat attggcggct 3000 acggtttcct agtatcctca acattctctt gaatcctggc ggcaacatta taagtacatg 3060 aaaaaacgct taccacctgt atctgattcc gatgaatcta attattgcca aaggataatt 3120 gtaaagcctt actcgtccca aaaggattat acacaaagca cacatgaaca aactctatca 3180 tccccgattt ccaagtctgc ttcggtttca aaaagcgaaa ataaagcttt agtgaataat 3240 aaaaggtatt ctgacagtta cttctatttt tctaagatga gacgcatttc gatagatgtt 3300 gattatgtag atgaggacct aaacttaatc aatgcatact tatcccaatt tggaaaaaag 3360 agaagtctaa acgaattgtg tgctctgttg agtagaaggt tttctaaccg acatacattt 3420 tccgaatgga gggcgctttt tatgcatttt tttcctttta taaattctga aggagttgat 3480 cctgctattt tatcagatag agaaacatct gcaatgcttg atgaaacttc ggataatgag 3540 gttgctgata ttgacgacca aatgatagaa aggaaatatt tatttagtgc ttctgaaccg 3600 aatactgtca aatctaccaa tcgattgata ttctctgaaa ggaaagcata tgcagctgat 3660 gactcgattg ataatacacc ttcgaaagta cccattgtta atagcttaag tgatccgcga 3720 accaatagac ctttctttta ttcaaaccca gacagcatgt accgctctat atctaatccc 3780 ttacacttgg ttgattctca acatttatct ccattaaatc gaaaaactca ttttaacaat 3840 cctattggtc aaccccaatt tacttgtctc gatgatcacg aaaaaacctt gcgtgaaact 3900 tcatttagat cgcttgatga catgagttta agaaaatcca attctgataa tattttcgtc 3960 aaacctggtg aagacctcga gattcctttg ctgagtgact atagtgatag tgaaaacatt 4020 tcagaaaagt cttcagatga tgaagaggct tttgagaaac aagtgacatc aagttactct 4080 tcacctataa aagtaaaatc ccaaggaaaa agctctaaag ggtcatcagg attagatgtg 4140 cgtgaacatg aaggctccga cgatgacgcc gaggtttttg ttgatcggtc tccagaaagc 4200 tttggtgcca caaaagtcgc tcacacttcg ttagaaggaa atgcagcttc tcataagaaa 4260 gtggaagaga acatgcagca accggttacc aaaaagcaga aaaaatacag aatggttaac 4320 gaagaagctc ataccggtcc gactataatc ataccgtcag ataataatga aaaagtaact 4380 acattacctg caggtcatgt acccagtgaa gagaaaggaa aatttattaa cttagcaatg 4440 catgaattac aaaatgaagt ttctatttta aggtcgtcag taaatcaccg tgaggttgat 4500 gaagcgatcg acaatatttt aaggtacaca aattcaacag aacaacaatt ccttgaagct 4560 atggaatcta cgggtggaag agtacgaatt gccattgcta aactactttc aaaacaaact 4620 tcttaaattg ccgagcatct ctgcccaaat tctatttctc taaagagacc taaacttgta 4680 caatattacg aatcttttta tgcataattc atgattttat tatataaata ttttatattg 4740 aacttaacaa aattcttttt gtttctggat ttagtaggtg tgaatatttc aattctgatg 4800 agccgattat atttgctttg atgtagcaga gtaaatcaac ctttttagaa aattcactta 4860 ttatctttgg aaaagtagct aaacttccat ttttataact tcctttacat tttaacttgt 4920 gaatttgtcc aatcatcata tgcaaatgct tggatcaaat ttctagcgat ggatagttta 4980 gggggaaata aaattggagc aggtccatcc ttggcatccc attccaaaga acgaagaact 5040 tcctctcggg aaaaaaaacg cacatcctct aattctaagt ctttatctct ctggatttta 5100 gcattttttc gggcaattcc aaaacaagcc aacattaaac tttgaggaaa aggccagggt 5160 tgactagcat aatataaaac cttttctacg tcaactccag attcttcata ggtttcacgg 5220 acaacggcct cttccaagct ttcccctggc tccagaaagc ctgccagaca tgcatacagt 5280 cctttcggat ggcgcaaagc tcttccaagt aaaatgtgtt gcatatcatg agacaatata 5340 accattatta cgcatggatc tgtccgagga tactggtaat tattaatacc cttctttgaa 5400 ggacagtttg agtcgtcgtt caataaaacg tcactgcaga ccaattttgt accgcccata 5460 gtaggtatgt tgcgttttcc acaacccggg caaaatctgt accttgaaat ccagtcaaga 5520 atagagcgtg caaaagcaca agcaccagaa tccgatgcgc tcaattgata ttgttcggtg 5580 aagatagagc gaagattaac gaaagtacct ccattgtctc gtatcgattg ctgaagttca 5640 tcgatgccag taatgtcaat ggcaaaaacg ttgtgttgac tccaattatc tgttggtcca 5700 tttctttctt cgttgcccat gtagacaagg acaggtaaac tttctccttt ggaaaatcgt 5760 tcagcaattt gtttatcagt gtgctcaaaa ggggagaacg tgaaatattt ggatatctga 5820 ggatatgaaa gagtgaccaa tttatcgtcc tttacgagta gagccggatt taagtcacaa 5880 aaaggaagaa agcgagtggt atgatcataa aaggctttat ttaaaaattc tcgattagac 5940 ctaagaaacg aaagcctatt taatgagctt cctgcgaaga actgagaagg ggcagtcgga 6000 agccttgaaa aacgttagaa aactcatttt tttaagatta ttatatcaaa aattgatttt 6060 atgtgttaca ttgcacatgt attagcaagg gttgagcggt acgttccatg agcatgcaaa 6120 acagatgata tgaattatca agtttgaagt agctttaaat agaactaaca attaactact 6180 tactcaaaat gtcgagctat tttgaaaccc tgcatactta aacttgattt ctgaaagacg 6240 aaaagaatat taaacctaac caattattaa aacagaattt tgcaaatctc tcgaataaat 6300 tctacaattg tttaactgtt aaaatacgca gaatagaaaa tgaaagatgg aaatgaagaa 6360 cagagaggac cagaaggagg gttatttatg caccagcgta atggtaatgg tacaatttat 6420 gagtgaacta aaagtcgaac ccaagttgca agtaaaaatc taataaaatg atgtaaacga 6480 actctcagct gggaaaacct taaagttcca aatgaaaagg gatactgaat atgaaaaagt 6540 ctccgttaaa tacgattgcc atacaacttc tcaaatgcca tgaagtattt aacgaatttc 6600 gttaaaaaaa taattgtaaa catattggta tgtgttttcg caattattaa cgccttggtg 6660 agtcataaaa gtatcattgg aataaaaata gattttgttt gtttgttttt ttggttaatt 6720 cctaaatgga cagttacggg aattgctttg agttgttttc gttatgttga cgattaatta 6780 actacaaagt tctcacgtgt cagtgtaaca atgttaccta gacttttagg tacctattta 6840 tttaaaattg ggtctatgtt tattttacaa gcttgaatca agtaaatata tattttctaa 6900 tcatatgaat actaaaaaaa tttttacaaa ggaacccagc aaaactatca aatggagcca 6960 aagtagctta tttatttagt atgaatgtga tacgcaacgc gacgtgtcgc gcgtttaatt 7020 tactggctta atacgcgagg cgaggctttt gtttacaaac aatactaggt gaatatgaga 7080 aaatatttga gtaaacaaac aaaatcaaat tgtatatata tccaggatac tcctccaaac 7140 ttccacagaa aaaaagatag gtttatcttt ttacttctag aggaaaacct gcatcttgct 7200 taccgaggcc attgctgaat attaaagcca gacataagta ggattaacca acaggtgaat 7260 tcatcagcct cccaaggaat atatatacat acttcttctt cctaaaaatc tttccgagtc 7320 aatccggaag agtatggact tctattcagt gaagtctcag ccgtttgttc gatctcctct 7380 agtcgaccaa aatcccagta tacaaaatat aaacgaagaa gtaaagagag atattcaaaa 7440 tcctcttagc tataaaacag aaacttcgga caaagaactg tgtcaaactg cagcttgcgc 7500 aacttcatgc tccgactggt accctcaaca acaaacgcac atgcctcatc aaaatgcctt 7560 tgactctgct aaagccacag caaagatggc tctcccaccc actgcttttt caaactactg 7620 tgtaaaacct tccctaacgc gaaacaagga tataccaaga accagcattc gagtttccaa 7680 acttcgttac tggcaaagag attatcgatt ggcgtttccc aactttatat tttactttga 7740 caacgttgat gaggaaatca agcgtcgtgt tacgcaaaag attaataatc ttggagccgt 7800 aagtagttca tgcaagaact tgcgcagatc aaaactaaca catatataga aagtagcaac 7860 attatttact tttgaagtta cacatttcat taccaccagg actaccgacc cagaaatgtg 7920 ccagccgaat gatgtacttt acctttcgaa aactgccaat atgaaaattt ggctcctgga 7980 cagtaagtct tcttaatata tcagtgtaac cttcgctaac tttcttagaa ctattgaaca 8040 gaatcctctt tacattactc aactctgata gcctggttaa tacctcagct tcgtgcttgc 8100 aatctctcct agacggtgaa aaagtgtatg gtacatcaga caaagacttt tacgtgccaa 8160 gcaaaaacgt cgagtacttt cgtgaatact tcctctgcat tagagattta tcacaatact 8220 ataagccaat tgcagtacga gaatgggaga aaacattgga ttctggagag atcttatggc 8280 caagtcttgc tataaccgca caaggaagat gtccatttaa tactggtaga agaagggagt 8340 taaaaatcac aaaacataac catccagctc acgaaatcag aaaacagctc ttaagttgca 8400 ctaatcaaac taaccaaaat aacgttgtta aaaattcagc gagtgtgttg gtgcgtcaaa 8460 tcatggggga ctataatatc acagaatcag cagttgatgg tgcaaaacaa atgccgacag 8520 agtttccaaa gccagaaaac ctcttaccgg tagagaaacg cgccgcaatg tctccactta 8580 accttcttga acctcgttta ataaacaaac aaaacacctt ggctaaccaa agtcctcgac 8640 aaccacctaa tgccttcgat gcagatcctc tagctcacaa gaaggtgaaa atcgaaacaa 8700 aatcaggata ttgtgaaaac tgctgtgaga gatacaagga cttggaaagg gtaagttaaa 8760 ccaatcatag caaaaacagc actaacacat cgatagcatt tgggcggaaa acatcataga 8820 agatttgcag agaaagatga aaatttccag ggtttagatg atttgttttt gctaatccga 8880 cgcccaattc ggacaaatta acgttagttc aagttttaag gatgtctcaa aaattccaga 8940 aagcaagttc aaacattcaa ataaaccgta aaatcaatat atcctttgtc caaatgaaaa 9000 attcaaaata atctgctaaa agggaagaga aaattaacaa tataatgatg tgttgtagca 9060 ttcttttctt aaaccaaggt caggcttaag cctatgattg taacaaacaa tgcaagtaaa 9120 gctccaaaca ttatcgagtt taaatcaaaa tagatttaaa ataagttaga ctggttttcc 9180 aagcgtggaa agctcattgg tgatacactc tttcaaaagt tcagatttga tttgcatcat 9240 tccttccttt gcgttttctg ttccaacaat ccctaataat aatgggtctt tggagtaaag 9300 tttatcttca gccccatcaa ttgaaatggc ggctattaat aatttccccc tttcaaactc 9360 aattattgtt tcaaaaagta catctctttg atgagcaatc acgtcgtctg tagactccgc 9420 gaccaaaggg ctagggttgg ttgcagtata aagtgaatac atgttgcctg ctaaagccgc 9480 aatagatcta acccttttag ctaaatccag acgttttaaa ccatctttag gatcttcaaa 9540 agaaacataa gctagcagcg agccagtagt ggtaaaaacc ctagtttgtt aatacctcag 9600 aatatttcaa caataaactt atatatctaa gctccaaaat agtacaggtg tacccactgg 9660 atttgaagta agaatgaact tcaaattcac taaatgctta catgatagac ggtacagttt 9720 cctcaactgc ctgtttcatc aacgacgaca acttctttgg cttaatcatc ttcgaattta 9780 aacttagata gcagtaaagg tagcaatatg tattttaaag tccaatcggc aataacgatt 9840 taacctgttt tgaatggtgg ttataagtag tttgtaagct acgcagtttg gtatctgatt 9900 taaggatacg tagaactgcg gtgagttttc cttgtggtct attatattac aatacacagg 9960 ttgtataagt agcaactgag tataggtatt gtattaactg ggttataatg ttacctatca 10020 ctaatatagc tcataactga actgaggaac gaggttcagt tgtaacgcta tttataatat 10080 ttctaaatag ttgttatcaa cgggtatcta tgtatataga aggatagtta cccgtgatta 10140 tcaataaacg gatcttagct agtattccaa catatgacat atagtgatac gcaacgtagt 10200 gtagcatagc gtagtgtagt attgctgaca tagttggaca atatacggtg gacgtaatgt 10260 gtattatgtt aagtaatctg ataataaata atattgttat aagattccga atattttatt 10320 aaagtaaaaa atgttaatcg acatatatac atttttattt ctttttattg tgtttgaaaa 10380 ttagggcttg gtagaccaac gttctcccaa cgaatgcttt atttagaaag ctgatttgca 10440 tatgcagtcc gtactatttg ggcctacaga gacttaccat tagttacata tacaaatgat 10500 cttcccttca ttatgaaatt aaaaagctaa ctattttcta cagtttgaga aaaaatgact 10560 acgtttcgtc gtgcagcttc agaattcctc aaacattaat taggataagg attacccaat 10620 actaaaggga caaaaacggg ttaagatgta tcataaaaca acacaaagtt atctataata 10680 tgacatacca ctaataacat agcgagtcaa aagcgacgta ctcacttccg aagttgttcg 10740 caatataagt aattaaattg ggaaaaacac atgtgttaaa tcgtttcgtt aaaagctata 10800 gttaagtcga aacaaattat acggccatta aactgccaat aaaatgaagg accaaccgag 10860 gacgaacggc cacaatatct tctggcaaaa taaagattac ggcacccaac tttctggcga 10920 tagaaatagc aagacgagct aaacgatgtg ttagtaatga aaattaaaaa tatatcaaat 10980 atatatacat accattttga atagcaagtt cttcagtaga accatcggta acaagattgt 11040 aatcaacata ttcgctctta attccatgaa gtacgtctaa gacgaacaca ccagtggaaa 11100 tagaaggatc acggaatgaa cgaatttgag aacctttacc acctttagca gccatagaat 11160 tggcccacgc aaccatgtca ctatctgaaa gagttttacc tccacggcta agactatgta 11220 gagttttggt aatgttcata cgcatcattt gccaaaccaa tgctaaggtg agtgtacgag 11280 aaccgtcagt aatatcagca ccttgtattc ctaccaaaga aaaaccttga ttttttccaa 11340 ggtccactgc ataattacag ttttcaacag ctttgaaacg catcatttca tctccagatg 11400 caggtgcctt gttcaccttt ttccagttaa cggtattagg tgtgatttta tcgtaagctt 11460 gcaacaaaat caagccatct cgtaaattat tgaagaagtc atgaatggat ggagtaacat 11520 caagagagtt caaccacaag gtaaaaacac gtgcctcacg ctcaccttct gcatcaaatg 11580 gttcaatctc cggcttttcc tcttcattta aaggctccaa acctggatga gtattaaaga 11640 gatgagcaac aaaggcaagg ttaagcttag ggttccctgc aaccatagcg gtaggtgtaa 11700 gatatttgcg gcaatccaat ttttcagcat tctgtaaaac ctgttcagca cgctgcaaaa 11760 catctgtagt ttgaagagga gcacgtgaac agagttcggg agctaattgg ttgagcagca 11820 cagtataatt ctcgccatct gaaacatctt ttgagaagtt agagacagta cgcggccaat 11880 tggcagcctt taagtgataa ttgaaccagc ggagaagaat tttctcagga gggagacgga 11940 gaaattggtc aagggtttca tcctcttcga gaaggcggta aagctcggga tgtaaagtaa 12000 tatcaatctt tccaaggaga ccgcggcgaa tgatttgcca aacaagacca agaatcaaat 12060 gttcacgacc ttctaaaata tcgccggcac caatgttggt aatggagata ccacccatag 12120 cttttgcgga gttaataaca acattgttat tttcaataca tttgaaatta tcaagaggct 12180 tgttatttct ctgtttattg agtacacgct catcaatggt gtcgggaacg ctgtcattaa 12240 ttaactttga gaggattaaa ccatctttgc attgatcgaa aaactcaaag gtttcagtgt 12300 tgatggggac tcgggaacca acatcagggt ctccagctaa gacggaatta atatgcttga 12360 taaattctct tcgctcttcc tcattaatgg tatgagaaac acttgaggaa gatcctttga 12420 tagtaatccg accctttttt acttcagtac cttctacacc tttttttaaa acattgaaaa 12480 tctatatgca ttagtaatcc aattgatgaa gcgatataga gacacatatc gtgaaaatta 12540 cggaaaacat tacttactcc tacaaagtct tcgggttcaa cacgtccaga cgaatcaacg 12600 ttaacttcac gaattgcttc acggacctca tcgtaagaac ccttctttga atcttcaaag 12660 gctttaatag tggtaggttg atctaaatat ccctttccat ccacatcaag tttgttaaat 12720 tggtcggtta aggttagaat ttcctcatta gtgagctccg gatacttctt ttgaagttta 12780 agagctaaca tttctttaaa agtaaaattt gaccaaaaaa tgtatagtaa acgaaaccac 12840 acgatgtgtg ctttgggtgg cttgcagttg ctacgtgaca aggattaacg tcgtgttgtt 12900 gatgcacata catcatactt acagaagcgt agagcaaaac tttgatccgc tcgctaaatg 12960 agttaataca cgtttgctta gccaatctgt taaaagttaa tttgcaattg taaaaagtaa 13020 tttactactt gacgatgtct tgcgttgtag ctttagattg aatatatagc tgggatatca 13080 actacattga attttaattt tttttacaga ataaaaagct aaacgtaagt ccatatcaaa 13140 ttagcgatat taccgaattc aaatgccata aacatcacaa actagcaagc tctttcaatt 13200 gaagtcaact gatgcatcga cttgaaaatt acttagtact atatgtcaag aagccaaaat 13260 ttctacttac tatgatagta gatcctttgt aaaacgttgc agaaagtttt tccggccgtg 13320 aaaattcgtg ttttttttct tttgttcaag ggtttaggtc actgaagcca acaatttttg 13380 atacaatata agaaaaagaa gtaattcccg cttttaactg cgcaatagga taaaagatta 13440 gccagatgtc acagggttaa acttttaacc tgactacctt ttcacgtgta tttccagtct 13500 cgtttataag ctgcaatata aatattgtat gatattactg cgtgcaccaa gattctctta 13560 tattattttc ttataatcta caaaactcac aatactacta taacgatgct tcagaagatt 13620 agctgttccg gtattgttga agcatggtga atttcctttg cggctgctgt tgtaaaatat 13680 tgtctgacaa ctatccaaat aaaacctatg ggatttttgc aaaaggcaaa cactattttc 13740 atagaggcac cgcgttgcag ggattttcag cagagatgat tcaatattgc aatcaaacac 13800 agtagatata aacataactt gaaaagctaa tgaaatacat aaaacataat tatattaacc 13860 ataatattct taacttattg gtttcttcaa cacttccaac ttcaatgaag caacaagtta 13920 gaggtttaac ttctccacaa cgccaaaatt gcgacttaga tgataaaaat attaaagtct 13980 agatagagct cagaaacatc aaaaaaaact atggaatatg atgaggaaga agtaaaagtt 14040 ttgaaagaag ttttaagcgc gttctttttg tacaggcaat atgctcatac aataacacaa 14100 cagaagagaa aatcgatgag caggttgtct tttgaacaca aggacttact cttacaggac 14160 tctgacaaca attttttaaa gcatctttca aggattgatc aatgtatcga gcagaacagc 14220 gtgcttgctg aagcaatcgc taacgcagcc attcctgtgt tctgcagtga tttcgatcaa 14280 aatgagttat ttcatgtcaa tgttgatatg atgcaaaaag tttcaagcac tctcaagcaa 14340 attgcgagag attggtcgac cgaatgtgtt gaggaacgcc gtactacata tgctcctttc 14400 atcgaggaac taaattcact tttcccatct gattctatag acagatctaa aattcgtgta 14460 cttgttccag gttccggctt aggaagattg gcctttgata tagctgtgga aggtaggtac 14520 acttgatact atcaatcaaa aatagcatga tttattattt atctgattac atgttttcta 14580 acttctttct aaatttggat ttttggacat agcttctaac atttaatagg ctttgcatgc 14640 caaggaaatg agttctcata ttttatgctt ttaacgtcgc atttcatact gaattgcgta 14700 aagcaggaaa atcagtttct tgtgtatcct tatattcatt cattttcgaa ccatgtcatg 14760 cgtgatgacc aggtgcgttc attaaatatt cctgatgcag ttccctctca atatctgcgg 14820 aattcacaaa acttttcaat ggcagccggg gatttcctgg aggtatacgg caccgaagaa 14880 agtcgtgatt cgtttcaagt agtagctacc tgcttcttta tagacactac aaaaaacata 14940 ctggactatt tggatacaat taaaaactgt ttggtagatg gaggttattg gataaatctc 15000 gggcctttat tgtatcattt tgagtcagaa ggtacttcta attctaacag tgatagccag 15060 caacaacctt tcgttgaatt gactctcgag cagctgtttt acgtgatgga tagtatggga 15120 tttgaggttt taaagcacaa ttcggtcgac acgacttata tgggggacaa acgaagtatg 15180 cttgaatgga tataccatcc tcattattgg gtctgccgtt tgcaaaaatc aaaattacga 15240 tttcaataaa aatttttgaa ccaacattga atattacgac tttaatcatt caaatattcc 15300 tttagcataa ttaacaaagc taattgataa cttgtacatg aaagtaaagc gattattttt 15360 gcatctacta tctacgtata aaactgccta cattaaataa gccattcgta cgcttcaaaa 15420 actttataag ccgcatttga aataaaggaa acggaaaaac ataaaggctt tgaaatacag 15480 tatgagccaa attattaatt aatagactca caaagctttg ttcataaaac gtctcttgct 15540 gaagcaagtc caccacttgc tgggatgatc cttttcagtt gcatatacat gggacaaaag 15600 acgataagca agttcctgac gaaattgagt aagatatgta cgcattattt ctttttttaa 15660 tagttagcaa atgaaaaaaa aagcaagaaa gctattagcg gcacaaacat ctatatgtct 15720 aatgccacag tttgggtgaa tcttaccagc atcttgagga gaaaggggag gagcatataa 15780 tgcattcaag ggaaagccag cagagccagg aatagaaaaa ttctccaacg ctaaactatt 15840 aagttgacgt tcagcatcac gataattgag tccattaact cttcccaagc actcactgat 15900 aaataatgtt ccataaatta aagtacggtc tgctggtccc ttaatctcaa aattgcggaa 15960 gaaacaattg gcgcgaaaca gcccaatgca ttcatcaata atatccattt gactctcatc 16020 agctgtataa aaaatgttag aaagtactct aataacatta agaatagtct ttaaacagag 16080 ttgacaaata tctggaacat accaggataa gccggtccac gaaacttggt tttcaacggc 16140 agcattgcta tgtttcccgt ggtagggacg tccgtaagac ttaagaagga ggaatgatag 16200 gcctttcata acatgtcagc aacaaaaatt caaaacttta gaacataccg gcatatctaa 16260 tgtctagtgc ttatgatgtt gttggataac ttgagcacct gctgaatgtg ccgataggga 16320 gcatttcgtc aagcatcaat agtgataaat tagcttttct ttaaacaaaa tagcgaaaag 16380 ctatgtaatt acagtaaagc aatatagcgt gtcgtttttt tgttttgtga tcgggtctcg 16440 gtctctactt tataactagt tttcatcaat ggaaatgaca tagagccaat aaatttgtag 16500 cgagaaccaa attcataagc atttgcacga atgcatttat tgcttgaaaa attataaaaa 16560 cgtcaaaaaa agattttcat gtttggttat tttgattttg ggatctaacg tactgactta 16620 tatggggata gacggtcttt tgggaccgta aacattacta catcggaaac aattcccccc 16680 tgttaaatct ttctgtgttg gatattttaa tacagtttag taggtaatct gttttctcca 16740 gagtgacgga attgaggata tatctgaaag agcatggaaa acccttcccc aactagaaca 16800 accaatttgc aacgaattcg gtcgttgtac aggttacaag aagacaagaa taatttaaat 16860 ataccagaac ctattaatgg aaaagttcaa gaaatcgata caaaagagtc attggaaaat 16920 gtggatcgtt acggaaacta tcgctcagac tttaatgtta ataatttagg gttctataaa 16980 gttagtaaag acccaacatt agataaacca aaccctgcca aacgtcttgg caataaatta 17040 atcggccatg atgacatgct gaagtacgtt gatgaaagca tcttcatggt tgttcccggc 17100 gagtcgcatg accgcaacga aatatcagct aaagagcttt cccgtattca aaaatggaaa 17160 tcgatgtgtt caatacacct cgtttccggt aatcagctcc attcttttcg aaaaactcgt 17220 aagttaattt tacgtacatt taaggggatt ccagattgtt ggcgatctat tgcgtggtgg 17280 tcctttcttg tggattctct tcctgataaa aaactgattg acaagtatta ccaattgaac 17340 gagcagattt gtgactatga tgttcaaatt gacctagatg ttcccagaac agctgctaca 17400 catttcttat tccgaaaacg ctacattgga gggcaacgtt tactatttag agttcttcat 17460 gctgtagctc tctatatacc tcgtgttgga tacgttcaag gaatggcttc tattgctgcg 17520 accttgctca tttactatcc cgaagaacaa gcatttataa tgatggtaaa tttattggaa 17580 aatagaggca tgggggactt gttttcttcc gggtttgata cacttttaaa ggcttttgac 17640 atgcttaagc atgagttaag ttttacacaa tcaggcagac atctggcgga aattggagca 17700 gaaccatctg cttttgctac acgttggtat ctcactgttt ttcatcaatg cgtgcccttc 17760 catactcaat tacgtatatg ggatctcctg tttttattag gtggaagcaa aggtcaaact 17820 gtcaggttat tgcaagccac ttctcttgcg gttatacaag gaatgtggga cacgctaatt 17880 gatgcagact ttgaagtagt aatgcaagct ctgtcaggtg ttattcccat tcaaaacgat 17940 aacgccctgc ttgctagaat tcaattattt tgggaaaaaa tgccttctga aaattcttct 18000 aaaagtaaga gaaactgata tttctaactc ttttttaata gctttattaa ttgtggccca 18060 catgatgtaa catatgtcaa caagatgagg attgatatca cagagcttag cataatgggt 18120 cctgaacatt tatcattttc tttttctgtt ttaatttgga acgttgataa acattatttc 18180 cttgatacca caaaactttt attggtatca agagtatgcg ctttaaatcg atcctatcta 18240 actctctctt cttactaata ttataatttt aacatctcac caaaagaaat ggaattttaa 18300 cataaaatta attcaagtat atatattata aatactatac atatatatgt atacataata 18360 cctctccatc ttgcgacttc ctaggtgcgt cgtaatttct aattatgtat agcttaaata 18420 gttaaatatt accaaaacac tgacgacaaa taataaaata taaagaaggt agtaaatggg 18480 ttgaaaaatc aaataaaaca aggtatgggg ttactcttcc tcgttctctt ctacattctc 18540 ttctgaagaa cgagattgat gagaagacgc aacatcagca aacttaagga ttttgtcttt 18600 atacttggtg acatccccgg aactgtcttc tattatccag gactggacct tatcttcaat 18660 caagaatcgc ttggaactat tttcatcaaa aatcactaca acactggaat ccttcaagtt 18720 cacctccatc tcgataaaaa gtctctcatg ttttccttta caaacaaaag cgcatcgacc 18780 aacatcagtt aatagcataa ccctttgctt tcttttcaaa aacatttttg agagtccaga 18840 tggaaactta ttaccctcag gtacacttgg aatgggtgat acgaagaccg aggtagattc 18900 aatgatcgac tcagacgatg gaaccaactt gtaataaagt ctgtcaacag gcatctgatg 18960 gcttcgaagt gaagcatagc cataatgagc agttggagca gtgaaacgat t 19011 //