ID SPBC16H5 standard; DNA; FUN; 35660 BP. XX AC AL022104; XX SV AL022104.2 XX DT 11-MAR-1998 (Rel. 54, Created) DT 07-MAR-2000 (Rel. 63, Last updated, Version 4) XX DE S.pombe chromosome II cosmid c16H5. XX KW 6-phosphofructokinase alpha subunit; atp-dependent rna helicase; KW atp-dependent transporter; iron-sulpher subunit; kinase-binding protein 1; KW mannosyltransferase; peptidyl-prolyl cis-trans isomerase; ppa2; rip1; sad1; KW serine/threonine protein phosphatase; shk1; skb1; KW spindle pole body associated protein; ubiquinol-cytochrome c reductase; KW ubiquitin-activating enzyme; zinc carboxypeptidase; KW zinc-binding region2 signature. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-35660 RA Wood V., Rajandream M.A., Barrell B.G., Skelton J., Churcher C.M.; RT ; RL Submitted (04-MAR-1998) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk XX DR GOA; O42938; O42938. DR GOA; O42939; O42939. DR GOA; O42941; O42941. DR GOA; O42943; O42943. DR GOA; O42944; O42944. DR GOA; O42945; O42945. DR GOA; O42947; O42947. DR GOA; O42948; O42948. DR GOA; O42949; O42949. DR GOA; P23636; P23636. DR GOA; Q09154; Q09154. DR GOA; Q09825; Q09825. DR SPTREMBL; O42938; O42938. DR SPTREMBL; O42939; O42939. DR SPTREMBL; O42940; O42940. DR SPTREMBL; O42943; O42943. DR SPTREMBL; O42944; O42944. DR SPTREMBL; O42947; O42947. DR SPTREMBL; O42948; O42948. DR SPTREMBL; O42949; O42949. DR SPTREMBL; Q9USY8; Q9USY8. DR SWISS-PROT; O42941; CWFR_SCHPO. DR SWISS-PROT; O42945; DD15_SCHPO. DR SWISS-PROT; P23636; P2A2_SCHPO. DR SWISS-PROT; P78963; SKB1_SCHPO. DR SWISS-PROT; Q09154; UCRI_SCHPO. DR SWISS-PROT; Q09825; SAD1_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c16H5 overlaps not confirmed yet. XX FH Key Location/Qualifiers FH FT source 1..35660 FT /chromosome="II" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c16H5" FT /map="IIR" FT CDS join(1..64,119..453) FT /codon_start=1 FT /db_xref="GOA:O42949" FT /db_xref="SPTREMBL:O42949" FT /label=SPBC16H5.14c FT /note="SPBC16H5.14c, len:132, SIMILARITY:Saccharomyces FT cerevisiae, Q06417, similar to 3-oxoacyl-[acyl-carrier FT protein] reductase., (326 aa), fasta scores: opt: 229, FT E():1.9e-09, (33.3% identity in 126 aa)" FT /partial FT /gene="SPBC16H5.14c" FT /gene="SPBC21H7.08" FT /product="putative short-chain dehydrogenase" FT /protein_id="CAA17912.1" FT /translation="DPNPHVVNIASSLAYFSAMGVGAYSSSKAALVSLHETLEEEVLSQ FT HPNFKFSLYVLGQIKSTMFEKDTPNRVLAPLLEPQNLAKIIIQNLYTNKSGRFYYPFYA FT RFMPLLRFFPLPIQKLARLFSGMDKIYS" FT misc_feature 1..459 FT /note="nominal overlap with cosmid SPBC21H7, EM:AL023286 FT S.pombe chromosome 2" FT misc_feature 65..70 FT /note="gtaagt, splice donor sequence" FT misc_feature 103..118 FT /note="ctaacgtgattaacag, splice branch and acceptor" FT CDS join(complement(3397..3662),complement(2204..3316), FT complement(459..2160)) FT /db_xref="GOA:O42948" FT /db_xref="SPTREMBL:O42948" FT /label=SPBC16H5.13 FT /note="SPBC16H5.13, len:1026, loew simialrity to WD repeat FT proteins" FT /gene="SPBC16H5.13" FT /product="hypothetical protein" FT /protein_id="CAA17911.1" FT /translation="MDWVALSKSCKTHLLDEGLDVSSIHCFDQYLIVGQCSGQVMVFDV FT STDNHFTLIQTFIAHKHSVSSIVCLPFEADGIVDLSIITLDESGLLCQWLLKTCDRRAT FT LQLCDGLCLKLFRLNNNFLAVTGTFLKIYLIRISNFQIVATWTGHEDWPILFPFKDEAL FT LIPVAYSDGSVSLWSVDWSALTFKRNSVTKADVKPTFGKVIDVVPADCISSNYALYVYS FT DAVVLLESHEKFIASYSLAEITSVFVLADGTACIFTLSSSTLLKLHQSPEPHFELISKY FT SGDFPWKSCTILKSKPVSLCVYPEKITFNWLTEGTVDSCNLCKLSNTAAVSYAYTDSLN FT LFLGTTSGLVMFSLFDWYLHNDPAPLYSFTRVSGIVTYMKIFETEHSRSILVVATKTGK FT AYFYQQLQGERWRFLCERALQSSSITKIIHAKKSLSSGSSGLFIFMSLDGSLCALDESY FT NLLSYLPSDGAQVETLYSFPDLDQIYVAYDNFQLLNWDVVDQKCSEGNYSDIIDSSFIS FT IGTFDKSNLPTLYHGSCALLTDNLVTVFLDAHDLVLNLNFSNENYIEKTYIDEFLDFIQ FT PPFLNSDIEMEHQLLGTVFDQSSLHLGVGKPDGNAILRFDTEMKSIINTAPNCSALLLY FT LYFSLMVPLCKYDGLSDTKLTEGILLKLKDLKTVDYSISVLSYVWNNSGKVMQGIIKSM FT LSRTLELISPEELQRLIYYYFEFFTTTGGEYYLKKEVQHSLYILSLIVSLRPSAFDVSQ FT LKFLSSYLLQKSESMDYDLTAIRLLSNGFSVFSKHIDPAKFIYNLVLSSLENTKDLDDK FT NSILYRSIVDVSVSNAVLLLTCLCDEVYEQMKSNLRSVILKVVSLAIENTQSEFSLFNQ FT LITEKLLPILYSSRSVEEVHDVTNAIATQFPFACFDSKVEKYSYIDDGDLVVYEIAKRR FT KVVSKENAECDIQVLSASPSGDYFVGVSATQKECIIWKYSQDFVKFLNLSTPSLTIRKR FT ILLQTNKTNEVEIPEVLWISQSSAEVHIGSTFAIIDL" FT misc_feature complement(1290..1399) FT /note="Blast N hit to SPAC18B11 Z50728 S.pombe chromosome FT I, possible conserved domain" FT misc_feature complement(2161..2177) FT /note="ttaatcgacttttatag, splice branch and acceptor" FT misc_feature complement(2198..2203) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(3317..3331) FT /note="ctaacattttctcag, splice branch and acceptor" FT misc_feature complement(3391..3396) FT /note="gtatgt, splice donor sequence" FT misc_feature complement(3447..3479) FT /note="PS00133 Zinc carboxypeptidases, zinc-binding region2 FT signature" FT CDS join(5289..5298,5496..5607,5667..7593) FT /db_xref="GOA:O42947" FT /db_xref="SPTREMBL:O42947" FT /label=SPBC16H5.12c FT /note="possible alternative N terminal splicing, but no FT consensus branch" FT /note="SPBC16H5.12c, len:682, SIMILARITY:Caenorhabditis FT elegans., Q20694, glutamic-rich., (474 aa), fasta scores: FT opt: 145, E():0.15, (26.3% identity in 186 aa)" FT /gene="SPBC16H5.12c" FT /product="hypothetical protein" FT /protein_id="CAA17910.2" FT /translation="MRICELSLINSLVEETNASCVIHTGDFGFFERSSLPSISERTLRH FT IVQFSPLIKKLPRSKNFDYYPSNPIGDLKNSIASHPDCLLSELPQFLSQEKKFSVPVYV FT VWGACEDVHVLEKFRSGEYSIPNLNIVDELHSYLLQIGDMKIRLLGLGGPYVPFKLFDN FT GDGKGTIAGGQGTMWTTILQMGELIETAKSLLDREEARIFITHHPIGREGVLSQLATAC FT QADLTLSAGLHFRYGASYNEFCVNHSPEHYLQKLSAARAQFMEVYDTVKAEVEKMVTPE FT QHHLINNVVRLVSRMPDATNSYAMNNMLPGTAFKNLWNFNLLDASFGWTVFVVENGHVQ FT VESKSHGFNLGYRRMASRRNENYASHIPRSTSENTGTYYYANNRLVESQAQFTKNREAT FT ATPTEEEQIEGYDQEHTDELGMSRANTTEESAETHEVIEEKSGPPAAEEEPISGVAEKP FT SPNEEEQPAIGGKEEVDVEEVTKGTGNLELGETTTEVTILEQENAANVTRSQAQEGRRT FT DMQKGNDREFRQYSGEQRYERCGFHITPCNSEEEARSYFKDGTDSLITNIQIRTSLNRY FT KSPQAPQNVNPTNYAYVFVENQNAVSKALGSIKVPEGVRVNIMRDDSYYRQNRGWYRNN FT RMEGHGTGMRTNRGRGRGGRMNRMQHPRPLQSGGSVNKQSAEPTTHG" FT misc_feature 5299..5304 FT /note="gtatgc, splice donor sequence" FT misc_feature 5477..5495 FT /note="ctaataactatcccttcag, splice branch and acceptor" FT misc_feature 5608..5613 FT /note="gtatgt, splice donor sequence" FT misc_feature 5652..5666 FT /note="ctaaccttttttcag, splice branch and acceptor" FT CDS join(8101..8350,8400..9898,9945..10133) FT /db_xref="SWISS-PROT:P78963" FT /label=skb1 FT /note="SPBC16H5.11c, len:645" FT /gene="skb1" FT /gene="SPBC16H5.11c" FT /product="kinase-binding protein 1" FT /protein_id="CAA17909.1" FT /translation="MLLRDGRIPQYSIYPLPVPPMNSKTPTLGIVCSEGTISLSLEEGF FT EFVGVPLSGEGLKLRVEALAPSERLQEFLDDEVAYHPEENVHKVVGLSSAWLELDSEDT FT LIADRSEEVLLKEASYASYCGLSSIILNGPTSPMNVMRYARAVSSALNSTMNLKFLVQL FT AIESGHEDYFETWKMWDTIRSACGYHPRLKVALELPPACSPPIELVNRWYAEPIEMITM FT SCMAFVPNPNGYPVLGRKLRAIYALYLRLNPRILLWDNDAPEKIGDSPDYSIYMKHLFD FT SQPPAPLVEDLADSYKDYLQVPLQPLSYNLENITYEIFERDPVKYAQYEQAIFSALMDR FT DESSVTRIAVVGAGRGPLVDCALRAAISSSRTVDMIALEKNPNAFSMLLMRNRQDWAGK FT VTLVFGDMRTWNPDYKIDILVSELLGSMGDNELSPECLDGVQHVLDEETGICIPSSYIS FT YVTPIMSPKLWSEARNMNDPNAFERQYVVLMNSFDFLAADDEFRFQSLWSFHHPNKDSE FT VYTKNLHNKRFASVRFQASSPGILHGFAGYFEATLYKDISLSIMPATMEAKSPDMFSWF FT PIYMPIKKPMYVPENSQLEFHMWRLTDGMRVWFEWCANAYLVLRNGSQIKLSSTEVHNI FT SGKAFSCNMY" FT misc_feature 8351..8356 FT /note="gtatgt, splice donor sequence" FT misc_feature 8381..8399 FT /note="ttaaccaattttactatag, splice branch and acceptor" FT misc_feature 9899..9904 FT /note="gtaagt, splice donor sequence" FT misc_feature 9931..9944 FT /note="ctaatatttcctag, splice branch and acceptor" FT CDS 10649..12856 FT /db_xref="GOA:O42945" FT /db_xref="SWISS-PROT:O42945" FT /label=SPBC16H5.10c FT /note="SPBC16H5.10c, len:735, SIMILARITY:Saccharomyces FT cerevisiae, PR43_YEAST, pre-mrna splicing factor rna FT helicase prp43, (767 aa), fasta scores: opt: 3351, E():0, FT (69.8% identity in 731 aa)" FT /gene="SPBC16H5.10c" FT /product="putative pre-mrna splicing factor rna helicase" FT /protein_id="CAA17908.1" FT /translation="MEPAQKKLRQESKNPYLAHLNNGDDSEEVVSSKGLTRRATTVAQA FT AKAEEGPNNFFNDKPFSQNYFKILETRRELPVYQQREEFLKIYHENQIIVFVGETGSGK FT TTQIPQFVLYDELPHLTNTQIACTQPRRVAAMSVAKRVADEMDVDLGEEVGYNIRFEDC FT SGPNTLLKYMTDGMLLREAMTDHMLSRYSCIILDEAHERTLATDILMGLMKRLATRRPD FT LKIIVMSATLDAKKFQKYFFDAPLLAVPGRTYPVEIYYTQEPERDYLEAALRTVLQIHV FT EEGPGDILVFLTGEEEIEDACRKITLEADDLVREGAAGPLKVYPLYGSLPPNQQQRIFE FT PTPEDTKSGYGRKVVISTNIAETSLTIDGIVYVVDPGFSKQKIYNPRIRVESLLVSPIS FT KASAQQRAGRAGRTRPGKCFRLYTEEAFRKELIEQTYPEILRSNLSSTVLELKKLGIDD FT LVHFDYMDPPAPETMMRALEELNYLNCLDDNGDLTPLGRKASEFPLDPNLAVMLIRSPE FT FYCSNEVLSLTALLSVPNVFVRPNSARKLADEMRQQFTHPDGDHLTLLNVYHAYKSGEG FT TADWCWNHFLSHRALISADNVRKQLRRTMERQEVELISTPFDDKNYYVNIRRALVSGFF FT MQVAKKSANGKNYVTMKDNQVVSLHPSCGLSVTPEWVVYNEFVLTTKSFIRNVTAIRPE FT WLIELAPNYYDLDDFDNNKEVKSALQKVYQMAARSKKNARR" FT misc_feature 11606..11884 FT /note="Match to PF00271 helicase_C, Helicases conserved FT C-terminal domain Score 22.18" FT CDS join(13452..14249,14296..14394,14448..14601,14646..14713) FT /db_xref="GOA:O42944" FT /db_xref="SPTREMBL:O42944" FT /label=SPBC16H5.09c FT /note="SPBC16H5.09c, len:372, FT SIMILARITY:Schizosaccharomyces pombe, O60160, FT 2-alpha-mannosyltransferase., (390 aa), fasta scores: opt: FT 1179, E():0, (45.7% identity in 385 aa)" FT /gene="SPBC16H5.09c" FT /product="probable mannosyltransferase" FT /protein_id="CAA17907.1" FT /translation="MRISRLLIRVLLGFVILFITYILFPSIPKALVNTLNVYKLEERLN FT YYNDRLLDGNLKSKELENATFVTLARNADLYDLIETINIYENRFNSKHNYPWVFLNDEP FT FTRTFEVVMSRLTSGPTYFGVVNSSEWDIPKWIDMDIAHSNWNRLSREGVLYGGMKSYR FT QMCRYFSGFFWRHPLLDPYKYYWRVEPSTKLLCEVNKDPFRQLRLLNKTYGFVITLFEI FT GQTVPSLWNSTLEFIEKYPETLAKNNLWEWISDDNGKKFSHCHFWSNFEIADLDFFRSD FT SYRKYFDFLDKKGGFFYERWGDAPVHSIALSLFLDRNKLHYFDEIGYSHAPLLHCPRKG FT RCFCKPEEIDLSSNSSCIARFINLTNEDYDEL" FT misc_feature 14250..14255 FT /note="gtaagt, splice donor sequence" FT misc_feature 14282..14295 FT /note="ctaactattgcaag, splice branch and acceptor" FT misc_feature 14395..14400 FT /note="gtatga, splice donor sequence" FT misc_feature 14432..14447 FT /note="ctaaaacaatttttag, splice branch and acceptor" FT misc_feature 14602..14607 FT /note="gtaagt, splice donor sequence" FT misc_feature 14631..14645 FT /note="ctgacaatttattag, splice branch and acceptor" FT CDS join(15263..15298,15411..17231) FT /db_xref="GOA:O42943" FT /db_xref="SPTREMBL:O42943" FT /label=SPBC16H5.08c FT /note="SPBC16H5.08c, len:618, SIMILARITY:Saccharomyces FT cerevisiae, YEM6_YEAST, probable atp-dependent transporter FT yer036c., (610 aa), fasta scores: opt: 2181, E():0, (54.3% FT identity in 611 aa)" FT /gene="SPBC16H5.08c" FT /product="non transporter with ABC binding cassette" FT /protein_id="CAA17906.1" FT /translation="MSSKSASKLKREAKKAERLAAKGESVKPSKKNGTKNGKDKEVDGV FT TKDLSELSTSDPIFERSASGVLTSQPMSRDIKIDSYTLSFHGRLLIENATIELNHGQRY FT GLLGDNGSGKSTFLESVAARDVEYPEHIDSYLLNAEAEPSDVNAVDYIIQSAKDKVQKL FT EAEIEELSTADDVDDVLLESKYEELDDMDPSTFEAKAAMILHGLGFTQEMMAKPTKDMS FT GGWRMRVALSRALFIKPSLLLLDEPTNHLDLEAVVWLENYLAKYDKILVVTSHSQDFLN FT NVCTNIIDLTSKKQLVYYGGNFDIYMRTKEENETNQMKAYLKQQEEIAHIKKFIASAGT FT YANLVRQAKSKQKIIDKMEAAGLVEKPEPPRQFSFEFDEVRKLPPPIIAFNDVAFSYDG FT NLDHALYRDLSFGIDMDSRVAIVGKNGTGKSTLLNLITGLLIPIEGNVSRYSGLKMAKY FT SQHSADQLPYDKSPLEYIMDTYKPKFPERELQQWRSVLGKFGLSGLHQTSEIRTLSDGL FT KSRVVFAALALEQPHILLLDEPTNHLDITSIDALAKAINVWTGGVVLVSHDFRLIGQVS FT KELWEVKDKKVVKLDCSIEEYKKSMAKEVQSRDTTAKVKHLI" FT misc_feature 15299..15304 FT /note="gtaagt, splice donor sequence" FT misc_feature 15396..15410 FT /note="ctaacaaatgtttag, splice branch and acceptor" FT misc_feature 15675..16244 FT /note="Match to PF00005 ABC_tran, ABC transporter Score FT 119.15" FT misc_feature 16626..17126 FT /note="Match to PF00005 ABC_tran, ABC transporter Score FT 114.56" FT CDS join(17903..18043,18336..19163) FT /db_xref="GOA:P23636" FT /db_xref="SWISS-PROT:P23636" FT /label=ppa2 FT /note="SPBC16H5.07c, len:322" FT /gene="ppa2" FT /gene="SPBC16H5.07c" FT /product="major serine/threonine protein phosphatase pp2a-2 FT catalytic subunit(ec 3.1.3.16)." FT /protein_id="CAA17905.1" FT /translation="MSIDPANDSKLAPEANDATLGDVDRWIEQLKKCEPLSEADVEMLC FT DKAREVLCQENNVQPVRNPVTVCGDIHGQFHDLMELFKIGGDVPDMNYLFMGDYVDRGY FT HSVETVSLLVAMKLRYPNRITILRGNHESRQITQVYGFYDECLRKYGSANVWKHFTNLF FT DYFPLTALIEDRIFCLHGGLSPSIDSLDHVRTLDRVQEVPHEGPMCDLLWSDPDDRCGW FT GISPRGAGYTFGQDISETFNHANGLSLTARAHQLVMEGFNWAHDGDVVTIFSAPNYCYR FT CGNQAAILEVDDTMNQVFLQFDPAPREGEPVIARRTPDYFL" FT misc_feature 17969..18052 FT /note="Match to PF00149 STphosphatase, Ser/Thr protein FT phosphatase Score 23.07" FT misc_feature 18044..18049 FT /note="gtaagt, splice donor sequence" FT misc_feature 18319..18335 FT /note="ctaaccattttttctag, splice branch and acceptor" FT misc_feature 18336..19115 FT /note="Match to PF00149 STphosphatase, Ser/Thr protein FT phosphatase Score 641.77" FT CDS complement(20258..20944) FT /db_xref="GOA:Q09154" FT /db_xref="SWISS-PROT:Q09154" FT /label=rip1 FT /note="SPBC16H5.06, len:228" FT /gene="rip1" FT /gene="SPBC16H5.06" FT /product="ubiquinol-cytochrome c reductase iron-sulpher FT subunit precursor." FT /protein_id="CAA17904.1" FT /translation="MLAKQFISKSLASSLRRLLPVSSTASSLKGSMMTIPKFTSIRTYT FT DSPEMPDFSEYQTKSTGDRSRVISYAMVGTMGALTAAGAQATVHDFLASWSASADVLAM FT SKAEVDLSKIPEGKNLVVKWQGKPVFIRHRTPEEIQEANSVDISTLRDPQADSDRVQKP FT EWLVMIGVCTHLGCVPIGEAGDYGGWFCPCHGSHYDISGRIRRGPAPLNLAIPAYTFEG FT SKIIIG" FT misc_feature complement(20306..20674) FT /note="Match to PF00355 Rieske, Rieske [2Fe-2S] domain FT Score 265.04" FT CDS complement(21689..22189) FT /db_xref="SPTREMBL:Q9USY8" FT /label=SPBC16H5.15 FT /note="SPBC16H5.15 len:166" FT /gene="SPBC16H5.15" FT /product="hypothetical protein" FT /protein_id="CAB60139.1" FT /translation="MSSEITEGDLQKFHDEHFNAKAVNLWNVAFAQNDRGGNSESANVE FT YTQSVERYPDGTIRTLTDEQILWFRESEKRELMWKKEKEQLLKEKELRQKALDKERMVS FT SKPETNPKTPISLKELKDIEIYQNQFHYSAYEILEEEKILDNIFRKFTALPIKYWPATP FT IRG" FT CDS join(22464..22469,22510..22538,22581..22685,22776..24027) FT /db_xref="GOA:O42941" FT /db_xref="SWISS-PROT:O42941" FT /label=SPBC16H5.05c FT /note="SPBC16H5.05c, len:463, SIMILARITY:Arabidopsis FT thaliana, O82646, hypothetical 57.1 kd protein, (510 aa), FT fasta scores: opt: 711, E():6.4e-33, (37.9% identity in 354 FT aa)" FT /gene="SPBC16H5.05c" FT /product="peptidyl prolyl cis trans isomerase" FT /protein_id="CAA17903.1" FT /translation="MATLTNLEPLATGTVILKTTRGDIQIELWCKEVPKACRNFIQLCL FT EGYYDGTIVHRVVPEFLIQGGDPTGTGMGGESIYGEPFAVETHPRLRFIRRGLVGMACT FT ENEGNNSQFFITLGPTPEWNGKQTLFGRVVGDTIYNVVRISELELDANQRPVFPPKIIS FT TEVIDNYFTDIKPRSTKEEREKIANELAHQEKQKERNKLLKSGRRNKAVLSFGDEVDMP FT IVKKPLRQKTPVSRSSDTTTELSKDLISSSSSIHSTYSSAQTGLTSAKVSSDEYARQVD FT TLDTKLNSSSKSKVQEEISRLKSELRDLEKSGGSSNSKPVVVRPKKRNILTEELEKYKK FT SKKVVLGKRKNLENDEESTLRALSSFQSKIRNAEDEDVMDSQYGSKIEDTPCSLHNVPG FT CFSCFDRLGEKNITETNSNWFAHRLVAENDPTRRTEELRIQRAEELKDVPSARPKKLLM FT KRDII" FT misc_feature 22470..22475 FT /note="gtaagt, splice donor sequence" FT misc_feature 22498..22509 FT /note="ctaatctctcag, splice branch and acceptor" FT misc_feature 22539..22544 FT /note="gtatgt, splice donor sequence" FT misc_feature 22569..22580 FT /note="ctaacattatag, splice branch and acceptor" FT misc_feature join(22609..22685,22776..23139) FT /note="Match to PF00160 pro_isomerase, Cyclophilin type FT peptidyl-prolyl cis-trans isomerase Score 116.95" FT misc_feature 22686..22691 FT /note="gtaagt, splice donor sequence" FT misc_feature 22762..22775 FT /note="ctaattaaatacag, splice branch and acceptor" FT CDS join(complement(24973..25011),complement(24824..24925), FT complement(24279..24710)) FT /db_xref="SPTREMBL:O42940" FT /label=SPBC16H5.04 FT /note="SPBC16H5.04, len:190, SIMILARITY:Saccharomyces FT cerevisiae, PH88_YEAST, inorganic phosphate transporter FT pho88., (188 aa), fasta scores: opt: 444, E():3e-24, (41.4% FT identity in 181 aa)" FT /gene="SPBC16H5.04" FT /product="putative protein involved in inorganic phosphate FT transport; yeast pho88 homologue" FT /protein_id="CAA17902.1" FT /translation="MVSRWEKLKNNPQTKSIGISIFLMMITRVIDFSRPSLLWPLRILY FT ATINEFNLPWFIYSLTILDLTVLKYVEPATPMSGREHSKFVATTVRDYDLSKLLTSFKQ FT MLVTIATTLFMHLYMGYAPPLLLQSVSAARGLFDNSEVQIHVQNKPAIDELRRPFKSSG FT GLLGSFGQVLTDKKSVDEAELTKLKPT" FT misc_feature complement(24711..24726) FT /note="ttaataaaatgggtag, splice branch and acceptor" FT misc_feature complement(24818..24823) FT /note="gtgaat, splice donor sequence" FT misc_feature complement(24926..24937) FT /note="ttaacatgatag, splice branch and acceptor" FT misc_feature complement(24967..24972) FT /note="gtaaga, splice donor sequence" FT CDS join(25917..25997,26039..26119,26210..27268,27310..27975) FT /db_xref="GOA:O42939" FT /db_xref="SPTREMBL:O42939" FT /label=uba2 FT /note="SPBC16H5.03c, len:628, SIMILARITY:Saccharomyces FT cerevisiae, UBA2_YEAST, ubiquitin-activating enzyme FT e1-like, (636 aa), fasta scores: opt: 1238, E():0, (39.4% FT identity in 637 aa)" FT /gene="SPBC16H5.03c" FT /product="ubiquitin-activating enzyme e1-like" FT /gene="uba2" FT /protein_id="CAA17901.1" FT /translation="MPTLMQLSNDMKPLTFVEALRNFKSAKVLLVGAGGIGCELLKNLL FT MSGVKEVHIIDLDTIDLSNLNRQFLFRKKHVKQPKAIVAAKTASSFNPNVKLEAYHANI FT KEDRFNVAWFRQFDLVFNALDNLDARRHVNKQCLLASVPLIESGTTGFLGQVQVIIHGK FT TECYDCNPKEPPKTYPVCTIRSTPSQPIHCVVWAKSYFFPQLFSNDQESDGIIDNVSAN FT EMERREIAELARETTELNELRSSIGQSDNGFEKIFTKMFTKDIVRLREVPDAWTYRSPP FT KELSYSELLENAEKATSPWLNEQNVWNVAESFAVLRDSIRRLALRSKSSKDDLSFDKDD FT KDTLDFVAAAANLRAHVFGIQQLSEFDIKQMAGNIIPAIATTNAVIAGLCITQAIKVLQ FT GDLNDLKNIYLAKRPTRVLHCEKTCKPNPYCPTCSFVLLQLGVNDKNMTLRVLVDDILK FT SRLHYSEEVSVLNDKLIYDPDFDDNLDKTFDDLGINPAKNTILTVLGDSAVEKDDDGEE FT ATRVPLLIEVTFIDSNSTEGLPYQILSNATSIPLKQQPPSNSPEDSQVLTDEINEVNDF FT SSSERIVINLDEYDIIVDSKTSSHNKQLKRRPSNDTLTQEAKSKKQAKIHTM" FT misc_feature 25998..26003 FT /note="gtatgt, splice donor sequence" FT misc_feature 26024..26038 FT /note="ttaacaattggtcag, splice branch and acceptor" FT misc_feature join(26039..26119,26210..26530) FT /note="Match to PF00899 ThiF_family, ThiF family Score FT 142.73" FT misc_feature 26120..26125 FT /note="gtaagt, splice donor sequence" FT misc_feature 26192..26209 FT /note="ttaactcttatactgtag, splice branch and acceptor" FT misc_feature 27269..27274 FT /note="gtaagt, splice donor sequence" FT misc_feature 27297..27309 FT /note="ctaacaatttaag, splice branch and acceptor" FT CDS complement(28352..31180) FT /db_xref="GOA:O42938" FT /db_xref="SPTREMBL:O42938" FT /label=SPBC16H5.02 FT /note="SPBC16H5.02, len:942, SIMILARITY:Saccharomyces FT cerevisiae, K6P2_YEAST, 6-phosphofructokinase beta subunit, FT (959 aa), fasta scores: opt: 2944, E():0, (48.9% identity FT in 963 aa)" FT /gene="SPBC16H5.02" FT /product="6-phosphofructokinase beta subunit" FT /protein_id="CAA17900.1" FT /translation="MSGETVHGISCYSVVANTEDTYNQTLDFYQKLGFKKVASFGTSDS FT DNARVCNESLREDWMHVAGNNSAESVTIKFRLVPGELSLSPAAEDSEWRGQKSSLVFYY FT PNLLDLLKQLSADAIKYQAFPNEKKPDEVYVEDPLGNLIGFSDRYNPFAHANLKKSEES FT GAASNLESGLATPVVETLKKATTSDKPAGVKKKIAVMTSGGDSPGMNAVVRAVARIAIH FT RGCDAFAIYEGYEGLVQGGDMIKQLQWGDVRGWLAEGGTLIGTARCMAFRERPGRLRAA FT KNLISAGIDSIIVCGGDGSLTGADIFRSDWPGLVKELEDTKAITPEQAKLYRHLTIVGL FT VGSIDNDMSSTDVTIGAFSSLHRICEAVDSISSTAISHSRAFIVEVMGRHCGWLAVLAA FT LATGADFVFIPERPAEVGKWQDELCNSLSSVRKLGKRKSIVIVAEGAIDSELNHISPED FT IKNLLVERLHLDTRVTTLGHVQRGGIPCAYDRMLATLQGVDAVDAVLASTPDTPSPMIA FT INGNKINRKPLMEAVKLTHEVADAIEKKQFAHAMELRDPEFADYLHTWEGTTFIEDESH FT FVPKDERMRVAIIHVGAPAGGMNSATRAAVRYCLNRGHTPLAIDNGFSGFLRHDSIHEL FT SWIDVDEWCIRGGSEIGTNRDTPDLDMGFTAFKFQQHKIDALIIIGGFEAFTALSQLES FT ARVNYPSFRIPMAIIPATISNNVPGTEFSLGCDTCLNAVMEYCDTIKQSASASRRRVFV FT CEVQGGRSGYIATVGGLITGASAIYTPEDGISLDMLRKDIDHLKATFALEAGRNRAGQL FT ILRNECASKVYTTEVIGNIISEEAHKRFSARTAVPGHVQQGGNPTPMDRARAARLAMRA FT IRFFETCRANDLGNDPSSAVVIGIRGTGVSFSSVADVENNETEIEMRRPKNAWWRDMHN FT LVNILAGKTFAD" FT misc_feature complement(28565..28687) FT /note="Match to PF00365 PFK, Phosphofructokinase Score FT 36.99" FT misc_feature complement(28838..29047) FT /note="Match to PF00365 PFK, Phosphofructokinase Score FT 28.43" FT misc_feature complement(29216..29398) FT /note="Match to PF00365 PFK, Phosphofructokinase Score FT 28.67" FT misc_feature complement(29663..30598) FT /note="Match to PF00365 PFK, Phosphofructokinase Score FT 628.61" FT misc_feature 31181..35068 FT /note="gene free region" FT misc_feature 33186..35660 FT /note="nominal overlap with cosmid SPBC12D12, EM:AL035085 FT S.pombe chromosome 2" FT CDS 35068..35660 FT /db_xref="GOA:Q09825" FT /db_xref="SWISS-PROT:Q09825" FT /label=sad1 FT /note="SPBC16H5.01c," FT /partial FT /gene="sad1" FT /gene="SPBC16H5.01c" FT /gene="SPBC12D12.01" FT /product="spindle pole body associated protein sad1." FT /protein_id="CAA17899.1" FT /translation="MFTNTPVGGKRERQNGAHPAWSTLGANSAQIHQNTADLASKMHKL FT RYTKIRSPPTRVSIESITPKQRFPAPNFEQAYHSNIRYEQEESDNEEFENVVKNGHEAS FT TNVFYESDGDDEEFVNEEYENSIDEESDDEGYSLNEDTTATNASFRYPMNQRSTRKSQF FT YSSKFKPLLWFGITLFSTLLIITLLHKGQEFYSRS" XX SQ Sequence 35660 BP; 11324 A; 6561 C; 6837 G; 10938 T; 0 other; gatccaaatc ctcatgtggt caacatagca tcctccttgg cttattttag tgcgatggga 60 gtcggtaagt ggggttgatt ttataaaatt tgcttttcct ttctaacgtg attaacaggt 120 gcctattcat cttcaaaagc ggcactagtt tcgctacatg aaacattaga ggaagaggtt 180 ttatcacagc atcccaactt caagttttct ctttatgttt tagggcaaat taaatctaca 240 atgttcgaaa aagatacccc aaacagagta ttagcccctc tactagaacc tcaaaactta 300 gcaaaaatta ttattcaaaa cttatataca aacaaatcgg gtcgttttta ctatccattt 360 tacgcacgtt ttatgcctct actgaggttt ttcccacttc caatacaaaa attggctcgt 420 ctatttagtg gcatggataa aatttattca taatccacct acaagtcaat gatagcaaag 480 gtgctcccaa tatggacttc tgctgatgac tggctaatcc ataggacttc aggaatttca 540 acctcattcg ttttgttagt ttgtaataat atacgttttc ggatcgttaa tgaaggtgtt 600 gataagttca agaattttac gaaatcttgg ctgtatttcc aaataatgca ttccttttgc 660 gtagcactga ctccaacaaa atagtcacca gaaggactgg cggacaatac ctgaatatca 720 cattcggcgt tttccttgct gacgactttc cttcttttag ctatttcata aaccacaaga 780 tcaccatcgt caatgtagga atatttttcc accttactat caaaacatgc aaatggaaat 840 tgggttgcaa ttgcgttagt aacgtcgtga acttcttcaa ccgagcggct agagtaaagg 900 attggaagta atttttccgt gatcaattga ttaaataaag aaaattcgga ttgtgtgttt 960 tcaattgcca aagacacaac ttttagtata acggaacgta aatttgattt catttgctca 1020 taaacttcat cgcataaaca tgtaagcagt aaaacagcat tcgaaactga gacatccact 1080 attgatctat agagaatgct atttttatca tccaaatcct tagtattctc taaggatgac 1140 aaaaccaggt tgtatataaa ctttgcagga tcaatatgtt ttgaaaacac ggaaaaacca 1200 ttactcaaca ggcgaattgc tgttaagtca tagtccatac tttcggattt ttgtaataaa 1260 taggaagaca aaaatttcaa ttgtgaaaca tcaaatgctg aaggccgtaa actgacaatt 1320 aatgacaaga tgtacagtga atgttgcacc tcctttttca gatagtactc tccacctgta 1380 gtcgtaaaaa actcaaaata ataatatata agcctctgaa gttcctctgg agatataagt 1440 tccaatgttc tcgacaacat tgatttaatt ataccctgca taaccttgcc tgaattattc 1500 cagacgtatg aaagaacgga aatactgtaa tcaaccgttt tcaggtcttt taactttaat 1560 aatattcctt cagtcaattt ggtatcgctc agcccatcat atttacataa aggaaccatt 1620 agagaaaaat atagatataa cagcaaagcg gaacaatttg gtgcagtatt tattattgac 1680 ttcatttcgg tgtcaaatcg aagtatggca tttccatctg gcttacccac accaagatgc 1740 aaactggatt gatcaaaaac agtacctaac aactgatgct ccatctctat atcagagttt 1800 aggaaaggag gttggataaa gtcaaggaac tcgtcaatat acgttttttc tatgtaattt 1860 tcattagaaa aattgaggtt cagtactaaa tcatgagcgt ctaaaaaaac agtaaccaaa 1920 ttatcggtga gtaaagcaca agaaccatga tacaaagtag ggaggttaga tttatcaaaa 1980 gtaccaatag atatgaacga agagtcaata atatctgaat aatttccttc agaacatttt 2040 tgatccacaa cgtcccaatt taatagttga aaattgtcat aagcaacata gatttgatct 2100 aaatcgggaa atgagtacaa agtttcaact tgagcaccat cagatggcaa gtagcttaga 2160 ctataaaagt cgattaataa ctgataacac actgataact tacagattat aagattcatc 2220 caaggcacac aatgagccat ctaaactcat aaaaataaat aagcctgatg aaccagaaga 2280 taatgatttc tttgcatgaa taattttagt aattgaagaa gattgcaaag cacgctcgca 2340 gagaaatctc catctttcac cctgaagttg ttgataaaag taagcctttc cagttttggt 2400 agcaacaact aaaattgagc gtgaatgttc agtttcaaat attttcatat atgttacaat 2460 tccagaaacc cttgtaaaag agtaaagagg agctggatca ttgtgaaggt accagtcaaa 2520 caaagaaaac atcactaaac cagaggttgt tccaaggaat aaattaagag agtccgtata 2580 agcgtaggaa acagcagctg tattgctcaa cttacaaaga ttgcatgagt ctacggttcc 2640 ttctgttaac caattgaaag ttattttttc gggataaaca cacaaactaa cgggtttact 2700 ttttaaaatg gtgcacgatt tccatggaaa atctccagaa tacttagaaa ttaattcgaa 2760 atgaggttca ggagattgat gaagtttgag taaagttgaa gacgaaagag taaaaataca 2820 agccgtgcca tcagccaaaa caaatacaga tgttatctct gcaagtgaat atgaagctat 2880 aaatttctca tgcgattcca atagtactac cgcatccgag tatacatata gcgcataatt 2940 ggaagaaatg caatctgctg gtacaacatc aataacctta ccaaaagttg gtttaacatc 3000 tgcttttgta actgaatttc ttttaaaagt aagagctgac caatcaactg accaaagaga 3060 tacagatcca tctgaatagg cgacagggat taataaagct tcgtctttga acggaaacaa 3120 aataggccag tcctcatgac cagtccaagt cgcaactatc tgaaagttgg agattctaat 3180 gagatatatt ttcaaaaagg ttccggtaac agcaagaaag ttgttattta atctaaatag 3240 ctttaaacat agcccgtcac acaattgcaa agtagctcgt cggtcacatg ttttcagtag 3300 ccattgacaa agtaatctga gaaaatgtta gcaagaaata agttaaataa tgaatttgat 3360 aattgctgct cggctaatga gagttgctca acatacccag attcgtcgag tgtaatgatt 3420 gataggtcta caattccatc agcttcaaat ggaaggcaaa ctatagaaga aacggaatgt 3480 ttgtgtgcta taaatgtttg gatcaaagtg aaatgattgt ctgtagaaac gtcaaatacc 3540 atgacttggc cggaacattg gcctactatc aaatactgat caaaacaatg tattgaagac 3600 acgtcaaggc cttcatctaa caaatgagtt ttacagcttt tcgacaatgc aacccaatcc 3660 attttgattc gcaatcaaca acggtctaag gctgacatca attttgaacg ctgttcgaac 3720 acggcttccc aaataaccac tcaattcagt aattgttaaa cctttttaaa tataaaagta 3780 attgaaaacg cagaaaatga aattaaaaca atatttaggc agactaacag ttgccgcgat 3840 attcttgaat gtaaaattag caaattcgga acgcaaacga ataaacaaga tgcaacaagt 3900 atttgaggaa gagaatctaa gaaaaatgaa gaacttgcaa cagccataga caagaatgtc 3960 taacaaatag ccatgtaaac aattcgtcca tccgtcattt aatagaatgt atgcatcgac 4020 agctccgatt gtatcaatca ttacataaat ctcttcattc ttgaattata tacaacttac 4080 acttctccaa aatttatacc actgcacaca acttcgaatt ccactcggtg gtgggaatgt 4140 gctgctgtgc tacttgaagc acgcgaatac tatatgacct agttgatggg gcgatgccct 4200 tgcttccaaa tcttgacaat acttagtagt aagaatacag cgtacaaacg agtttaagtt 4260 atagtaaacg agcattattt aataacacaa aagagtattg ttgtacatag aaaaaaaccg 4320 aaaaaattgc taacagtctt attttattca atttgccaaa taaacagaac atttacatac 4380 ttcaaatgtt gtaaatttcg cactgcaact agtattcaaa tctcaacctg gaaaaacgat 4440 ataacgaaat tgaaatatac ttcagactgt agcatcatct actgtacacg aggcaaactt 4500 aagtcatagt atgtgtaaaa taagttaaca attccattcc aaagctgcaa catttaacat 4560 ataccctaat aaactctgcc gtcccgatta ccgagctttc tcaagaattt tgtaatcctt 4620 cattgaagca cctttttttt tcatatttat atataaatat atatattaat atatactaaa 4680 ttttattttt atttttattt tttgtggagt tttatactac agaaatacaa ttgtcacgtt 4740 aaaaatttca aaaactatct attaactgct gctttttgtg tatttatata tttaatttac 4800 tttacttcgt ttgtggtgga tctaagttat aacattacga agcaacattc tcttattgta 4860 gtaggaagta gtacagtgcc gaaactgagg catcatcaca aaacccttac tcaacaccat 4920 ttactgtttt atccgtttca ttagattttt acgatataat gagcgtggat gtaagtatag 4980 atctaatgaa tctttgcaaa aattttaaac taattacata aaagacggct aaaagtgata 5040 ttcaagcgga accttcaact gggacgctgg aaaataaatc ctctaaaacg tactcagatt 5100 ccgagaataa ttccacgttg gatgtttcag ctcaagtact cacattggat aataaatcca 5160 ggatcttatg tattgccgat gttcgaggta agtatgcgtt gtttatggat ttagagctgc 5220 cagcgagaat tcaaaagcac cccatcgggg gaattatcga cgatcgtttt actttttaag 5280 ataagaagat gcgaatttgt atgcttttgc atgaacttat ccataatggc ttagcaggag 5340 ttgaagcgca attgctcaat ttactcattt tgtcattaaa gatcctcgtt ggttcgtaaa 5400 agaattttgt ccatacactt tattctcctt agctattcct atccttaaaa ttactactct 5460 ttaatacgcg tttttactaa taactatccc ttcaggtgaa ctgagtttaa taaatagcct 5520 ggttgaggaa accaatgcct cctgtgtcat ccacactggt gactttggat tttttgagcg 5580 atcctcactt cctagcatat ctgaacggta tgttttgtgt caaaaatttt tatgtttcat 5640 ttttctttgt tctaaccttt tttcagtact cttcgtcaca ttgtccaatt ctcgcctctc 5700 ataaaaaagc ttcctaggtc caaaaacttt gattattatc cctcgaatcc aattggggat 5760 ttgaagaata gtattgcttc tcaccccgat tgcctgcttt cagaattacc tcaatttttg 5820 tcacaagaga agaaattctc agtccctgta tatgtagtat ggggagcttg cgaagatgtg 5880 cacgttttgg aaaaatttcg ttctggagaa tattctattc caaaccttaa catagtggac 5940 gaacttcatt cctacctatt gcaaattgga gatatgaaaa tccgtttact tggtcttgga 6000 ggtccttatg tcccttttaa gctttttgac aatggagacg gtaaaggaac tattgctggt 6060 ggccagggta ctatgtggac tacaatcctt caaatgggtg aactaataga aaccgctaag 6120 agcctgcttg acagagagga ggcacgtatt tttattacgc atcatcccat tggaagagaa 6180 ggtgttcttt ctcaattagc tactgcttgc caggctgacc tgactttatc cgccggtctt 6240 cattttcgtt atggagctag ctacaatgag ttttgcgtaa atcatagtcc tgaacattat 6300 cttcaaaaac tttcggctgc ccgtgcacag tttatggaag tgtatgacac tgttaaggct 6360 gaggttgaga agatggttac ccctgaacaa catcatctaa taaacaatgt tgttcgccta 6420 gtctctcgca tgcccgatgc aactaactca tatgctatga ataacatgct tcccggcact 6480 gcttttaaaa acctatggaa cttcaattta ttagatgctt cctttggatg gactgttttt 6540 gtcgtcgaaa atgggcatgt tcaagtggaa agcaaatctc atggctttaa tttaggctat 6600 cgtcgcatgg cttcacgtcg taacgaaaat tatgcatctc acattccacg ctcaacttcg 6660 gaaaataccg gtacctatta ttacgctaac aataggttgg tggaatctca agcacagttt 6720 accaagaaca gagaagctac ggctacacca accgaagaag aacagattga agggtacgat 6780 caggaacata ctgatgagct aggaatgtca agagcgaata ctacagaaga gtcggctgag 6840 actcatgaag taatcgaaga gaagtcggga ccacctgctg ccgaggaaga acccatttct 6900 ggcgtagcag agaagcctag tcctaatgaa gaagaacaac cagcaattgg agggaaagag 6960 gaagttgacg ttgaagaggt gactaagggt actggaaatc tcgagctagg tgagacgact 7020 acagaggtta ccatacttga acaagagaat gctgcaaatg ttacaagatc tcaagcacaa 7080 gaaggtagaa gaactgatat gcagaagggc aacgatcgtg aattccgtca atatagtggt 7140 gagcagcgtt atgaacgttg tggatttcat attacccctt gcaattctga agaggaagcc 7200 cgttcttact ttaaggacgg gacagacagc ctgattacga atattcaaat tcgtacttca 7260 ctcaatcgtt acaaaagtcc ccaagctcct caaaacgtaa accccactaa ctatgcatat 7320 gtatttgttg aaaaccagaa tgctgtttca aaggcccttg gaagcatcaa agttccagaa 7380 ggtgtgcggg tgaatatcat gcgtgatgat tcgtactatc gtcaaaatag aggatggtat 7440 cgaaataacc ggatggaggg acatggaact ggaatgcgta ccaatcgtgg acgtggacga 7500 ggcggccgaa tgaacagaat gcagcatcct cgtccattac aaagcggtgg aagtgtcaat 7560 aaacaaagcg ctgaacctac tacccatggt taatgatgaa tattttttgc actgttttca 7620 atgctgtttt agaactgatt tttataccat cttttcacct ttttactgat gttaatgcaa 7680 aagtttacct catgaatgat gaagttttca tgaaatttat ctgacgcact catttacctc 7740 aataactgcg aagccaaaat aactgatatg actcttttaa gatatctttt tcgaattcgg 7800 ttgtcattga caaaagggtg cttactttac tttctttcat atcgactttg tttagaaata 7860 ataaagtgat ttttgacaag attgattcgc agaaaactat atagtaaaaa taattaatta 7920 ctttatgcta gaatagcagt tattagcctt ttcttcttag aaaagatgta agttttaata 7980 gatcaaattc attaattaaa taaccaagtt gaaatttaaa acactcacaa acaataagct 8040 agctactcaa ctaaacaatt tttttttgtt tttgcaacac aaggtcccaa cccttaccgt 8100 atgttattgc gggatggccg tattccacag tacagtattt acccattgcc agttccgccg 8160 atgaattcta aaacgcccac tctaggaata gtttgttcag aggggaccat ttccttgtct 8220 ttggaagagg gttttgagtt tgttggagtt ccgttaagtg gtgaaggttt aaagctacga 8280 gttgaagctc tagctccgtc agagcgtttg caggaattcc tcgacgatga agtagcttat 8340 caccctgagg gtatgtttca aatttgaaag aaaatttata ttaaccaatt ttactataga 8400 aaatgtgcac aaggtggtcg gtttatcctc agcttggctg gagttagatt ctgaagacac 8460 actaatcgct gatcgatcag aagaagtgtt attaaaggaa gcatcatatg cttcttattg 8520 tgggttatct tcaatcatcc taaatggtcc aacttcacca atgaacgtta tgcgttatgc 8580 gagagctgta tcttctgctt taaactcaac aatgaatcta aaattcttgg tacaattggc 8640 aatcgaaagt ggtcatgaag actattttga gacatggaaa atgtgggaca caattcgctc 8700 agcatgtggt tatcacccta gattgaaggt ggccttagag ctacctcccg cttgttcacc 8760 cccaatcgag ctagtaaatc gatggtacgc ggaaccgata gagatgatta ctatgtcatg 8820 tatggctttc gttcctaatc ccaacggcta tccagtactt ggtcgtaagt tgagggctat 8880 ttatgcttta tatctacgtc tcaatcctcg aattttactt tgggataatg acgcacccga 8940 gaaaataggt gattcccccg actacagcat atatatgaag cacctctttg attcacagcc 9000 tccagctcca cttgtagaag atctcgcgga ttcttataaa gactatctgc aagttcctct 9060 tcaaccattg agctacaatt tggaaaacat tacttatgaa atatttgagc gagatcccgt 9120 taagtacgcc cagtatgagc aagcaatttt ttctgcgttg atggatagag acgaatcttc 9180 tgtcacgcga attgccgttg tgggtgcggg aagaggtcca ttagtcgact gtgctttacg 9240 tgcggcaatt tcttcatcta gaacggttga tatgatcgcc cttgagaaaa atcctaacgc 9300 tttttccatg ctattgatga gaaaccgcca ggattgggct ggcaaagtta ctctagtatt 9360 tggagatatg agaacatgga atcctgatta taaaattgac atccttgtta gtgaactttt 9420 gggtagtatg ggagacaatg aacttagtcc ggagtgtcta gatggtgtac aacatgtgct 9480 tgatgaagaa actgggatat gcattccatc ttcttacatc tcctatgtta ctcctattat 9540 gtctcctaag ctatggtctg aagctcgtaa tatgaatgac ccaaatgctt ttgaaagaca 9600 gtacgtggtt ttaatgaact catttgactt tttggctgca gatgatgagt tccgttttca 9660 gtccctttgg tccttccatc acccaaacaa agatagtgag gtttatacta aaaacttgca 9720 taacaaacgt tttgctagtg ttcgttttca ggcctctagt cctggaatcc ttcacggttt 9780 tgcaggatat tttgaagcta cattatataa ggatatttct ctttcaatta tgccagcaac 9840 tatggaagcg aagtctcctg acatgttttc atggttccct atttatatgc ccattaaggt 9900 aagttactat attttacgtt gcactgtata ctaatatttc ctagaaaccc atgtacgtcc 9960 cagaaaacag ccaattggaa tttcacatgt ggcgattgac ggacggtatg cgggtttggt 10020 ttgagtggtg tgccaatgcc tatctggtgt tgcggaatgg aagtcaaatc aagttgtctt 10080 ctacggaggt ccacaacatt tccggaaaag cgttctcgtg taatatgtat taaaaattaa 10140 tagtccttct tttacattat tgtttatggt ttaaaacggg tcttcaaacc atttttttgg 10200 agttttgatt ataaaaattt tttggattta gttaaatctg aatttaacaa aagtcgatta 10260 gttttaggat agctgttaca atcaagattt tgctgagaaa gaaggagtaa tgctcctata 10320 cttattgtct taaacgattt gccagaattt taactattgt tcttaaacat tcctttttac 10380 acaattaatt aacaggcaaa ttcattcaac tgaaataccc tgtcatttgc ttactatact 10440 agttaattaa ttttcattaa tgtattatat tagtccgaac ttgaaaatta acaacgcatt 10500 gcgttatgcc actcaatttt atataacgaa tgttaagata gatggtttgt tggaaaattc 10560 tttaactgct tgtagtacgg agtatgcact gtgttcttcg ccatttacag aattgtggga 10620 agggtttata taagggcgat tttcgactat ggaaccagct cagaagaaac taaggcaaga 10680 gtcaaagaac ccgtatttgg cacacttaaa caatggtgat gattctgagg aagttgtttc 10740 ttcgaaaggg ttgacgcgac gtgctacgac tgttgcacaa gcagctaagg ctgaagaagg 10800 accaaacaat ttttttaatg ataaaccttt tagtcaaaat tattttaaga ttttggaaac 10860 tcgaagagag cttcctgtat accagcaaag agaagaattt ctcaaaattt atcacgagaa 10920 tcaaattatt gttttcgttg gtgaaactgg ttctggtaaa acaacacaaa ttcctcagtt 10980 tgttctttat gatgaattgc ctcatttaac aaatacacaa attgcatgta ctcaaccacg 11040 tcgtgttgca gctatgtccg ttgcaaaacg tgtcgctgac gaaatggacg ttgacttggg 11100 cgaggaagtt ggttacaaca ttcgttttga agactgtagt ggacctaaca ctctgttaaa 11160 atatatgaca gatggtatgc ttttgcgtga agccatgaca gaccatatgc tctctcgtta 11220 ttcttgtatt attcttgatg aagcacatga gcgtaccttg gcaactgata ttttgatggg 11280 tctaatgaag cgtttggcta cacgtagacc cgaccttaag attattgtca tgtctgcaac 11340 tttggatgct aaaaagtttc aaaaatactt ttttgatgct ccccttttag ctgttccagg 11400 tagaacttac cctgttgaaa tttattatac ccaagaacct gagcgcgatt atttagaagc 11460 cgcgcttcgt acagtgcttc aaattcatgt tgaagagggc cccggtgata tcttagtgtt 11520 ccttacaggt gaagaagaga ttgaagatgc ttgccgtaag attactttgg aagctgatga 11580 tcttgtacgt gaaggagccg ctggtccatt gaaggtgtat ccactttatg gttctttacc 11640 gccaaatcaa cagcaacgta tattcgaacc aactccggaa gatacaaaat cgggttacgg 11700 ccgtaaagta gttatatcta caaacatcgc agaaacatcc ttaactatcg atggtatcgt 11760 ttatgtggtg gatcctggtt ttagtaaaca aaaaatttat aatccccgaa tccgagttga 11820 gtctttgctt gtaagtccta ttagcaaagc cagtgcacaa cagcgtgctg gtcgtgctgg 11880 acgtactcga cctggtaaat gtttccgcct ttacacagag gaagcttttc gcaaagaatt 11940 gattgagcaa acgtatcctg agattttacg cagcaatctc tcgagtactg tcttagaatt 12000 gaagaaacta ggtattgatg acctcgttca ttttgattat atggatccac ccgctccgga 12060 gactatgatg cgtgctttag aagagctgaa ctatttgaac tgtctggacg ataatggcga 12120 cttgactcct ttaggtcgta aagcgtctga attcccactt gatccaaatt tggctgtaat 12180 gcttatcaga agtccagagt tttattgctc aaacgaagtt ttatctttaa cagctctttt 12240 atctgttcct aatgttttcg tcagacctaa ctctgcaagg aaattagcgg atgagatgcg 12300 acaacaattt actcatcctg atggtgatca cttgacctta ttgaacgttt atcatgctta 12360 taaatcaggt gaagggactg ctgactggtg ttggaatcat ttcttgtcgc atagagcgct 12420 aatcagtgct gacaatgtaa gaaaacaatt gcggaggaca atggaacgtc aagaggttga 12480 actcatatct accccttttg atgacaaaaa ctactatgta aatatccgcc gtgctcttgt 12540 tagtggattt ttcatgcaag ttgccaaaaa gtctgcaaat ggtaaaaact atgtgactat 12600 gaaagataat caagtggttt cactgcatcc ttcatgtggt ttgtcagtga ctccagagtg 12660 ggtggtttat aatgaatttg tacttactac caaaagtttt attcgaaatg tcacagctat 12720 tcgtcctgaa tggttaatag aactagctcc caattactat gatttggatg atttcgacaa 12780 taataaagaa gtcaaatcag cactccaaaa agtatatcaa atggctgcta gatcaaaaaa 12840 gaacgctcga cgttaaaatc taatttactg ctcggtgaat tacaaatatt tagaagaagt 12900 ggatagcgtc tacttttaat ggtgttttgg ataattattt tgttgacttg ggatatttat 12960 acatattttt taattcgatc ctttatattt tgatctctac atttatttag acttggtaat 13020 atcagtgtat attactgcat ggggctaaac cagaactaaa attaataaaa tatttctaca 13080 gttgaaacta cttttcatat gcaatgaata atgtgtattg gtaaccgcgg taattttaag 13140 ttagcagttt tatttataat ctaaaggctt ttcctccgaa ataattatta acatgttttt 13200 taaaaaactt tttaaaaagt cgtgcagctt tatgccaaaa atatgagtgt attagttttt 13260 ctgacctacg gtataggcct ctcctgacac ctataatgtg attactgact tcactagagc 13320 aaagtgaata accgaaggta aaataattga tattcatttt gtcttgcagt tataatggaa 13380 gctaaatact agcattgaaa aactaaaatt tttgtagatt atttgggtta gtcggtattt 13440 atcaaaaaaa aatgcggata tcaagattgc tgattagagt acttttggga ttcgtgatac 13500 ttttcattac atacatcctc tttccttcaa taccaaaagc attggtgaat actttaaatg 13560 tgtataaact agaggagcgt ttaaactatt acaatgatcg tttattagat ggaaatttga 13620 aatcgaagga attggagaat gctacgttcg taactttagc acggaatgcg gacctttacg 13680 atttaattga aacaataaat atatatgaaa atcggtttaa ttcgaagcac aactatcctt 13740 gggtttttct aaatgatgaa ccatttactc gaacttttga agtggtcatg tctcgtctaa 13800 ctagtggtcc aacatatttt ggtgtcgtga acagtagtga atgggatatt ccaaaatgga 13860 tagatatgga tattgcacat tccaattgga atcgcctatc aagggaaggc gtactttatg 13920 gaggcatgaa atcatatcgt caaatgtgtc gatatttctc tggatttttt tggagacatc 13980 ctttacttga tccttataaa tattattgga gagttgaacc ttcaactaag cttttatgtg 14040 aagtgaacaa agatcctttc cgacaactga gattactgaa taaaacctat ggatttgtca 14100 taacgttatt tgagatcgga caaacagtac catcattatg gaatagtacc ttggaattta 14160 ttgagaaata tcctgaaaca ctggcgaaaa acaatttatg ggaatggatt tcagatgata 14220 atggaaaaaa atttagccac tgccattttg taagtgaagc gagtaacaat atttctattt 14280 actaactatt gcaagtggtc aaactttgaa atagcggatc tcgatttttt cagaagtgat 14340 tcttacagaa aatattttga ttttttagat aaaaagggtg gcttttttta tgaggtatga 14400 ccaaacgtca acggaagaat ttgcaacatt gctaaaacaa tttttagaga tggggtgatg 14460 ctccagtaca ttctatagca ttaagtttat ttctcgatag aaacaaactg cattactttg 14520 acgaaatagg atattctcat gctcctcttc ttcattgccc tagaaaggga cgttgcttct 14580 gtaaaccgga agagattgat tgtaagtata attaatatac tgcacatttg ctgacaattt 14640 attagtatcg tccaactctt cttgcatagc taggttcatt aacctaacta acgaagacta 14700 cgatgaatta taatgctttt gttgcaatca aaatgaacag aactttttag gctaacaatt 14760 tgtgtattgg aaatgtcatt atgcaacgag gtcaggataa ccctgagtaa gatattaaat 14820 gtattttatt gtgttttaat ttattactac aaggaattct tctcaaagtg tttacttcat 14880 tgcactgtta tcgtaagcaa gtcgacatgc gtaaatcaac agaatatttg tttttgtttt 14940 ggattcataa ctctgaacaa taattagtta aacaaaattt tctcttattt aacaatttat 15000 ttaaatccct taccagcact actattctat aattatttat taatgcacac actttctttg 15060 tcaaaatagt gtaacaacta tattgttata agtctcataa aatggtttaa catgcccatt 15120 aaaaggtccg tatttttttt aagcaattaa aattttttac gctatattta tttattgtat 15180 ttgctgtaaa tttatctgaa aacgtcacag gagttcctaa tgtcaatttt ttttcgacaa 15240 aattattctg tacttagcca acatgtcgtc caaatcagcg tccaaactga aaagagaggt 15300 aagttcctat taatgaatgc tgtagagaaa aaagtcaaat aaatagctta tttctaattt 15360 ttttcgattg cttttaaaat ttttaagctc aatcgctaac aaatgtttag gctaaaaaag 15420 ctgagcgctt agctgctaaa ggcgagagcg ttaagccctc taaaaagaat ggaactaaaa 15480 atggaaaaga taaagaagtc gatggagtca caaaagattt gtcggaactt tctactagcg 15540 accctatttt tgaaagaagt gcttctggtg tcttaactag tcaaccaatg agtcgcgata 15600 ttaaaattga cagttacacc ctttcttttc acggacgtct gttgatagag aatgccacta 15660 tcgaactcaa ccatggtcaa cgctatggtc ttttgggtga taacggttcc ggtaaaagta 15720 cattcttgga atccgtggct gctcgtgatg tggaatatcc agaacacatt gatagctact 15780 tgttgaacgc agaggctgaa ccctctgatg ttaatgctgt cgactatatt attcagtcag 15840 caaaagacaa ggttcaaaaa ttggaagccg aaattgaaga gttatcaact gccgatgatg 15900 ttgatgatgt tctattagaa tccaagtatg aagagttgga tgatatggat cctagcacct 15960 ttgaggcaaa agcagctatg attttgcatg gtttgggatt tacccaggaa atgatggcca 16020 aacccacaaa ggacatgtct ggtggttggc gtatgcgtgt tgcactttct cgtgctcttt 16080 tcatcaaacc ctctttgctt cttttggacg aacctaccaa ccatttggac ttagaagccg 16140 ttgtttggtt ggagaattac ttagcgaaat acgacaaaat tcttgttgtc acttcccact 16200 ctcaagattt cctcaacaac gtctgtacca atattattga tttaacttct aaaaagcagc 16260 ttgtctacta tggtggtaat ttcgacattt atatgcgtac taaggaagaa aatgaaacca 16320 atcagatgaa ggcttactta aaacagcaag aggaaattgc tcatattaaa aagtttattg 16380 ctagtgctgg tacctatgca aacttggtac gccaagccaa gtcgaaacaa aagattatcg 16440 ataaaatgga ggctgccggt ttagttgaga agcccgaacc tcctcgtcaa ttcagctttg 16500 aatttgatga agttcgcaaa ttaccaccac ctatcattgc ttttaacgac gttgctttct 16560 cttatgatgg taatcttgat cacgctttgt accgtgactt gtcctttggt atcgatatgg 16620 actcccgtgt cgccattgtg ggtaaaaatg gtaccggaaa gtctacattg ttgaacttaa 16680 tcactgggct tttgattccc attgaaggca atgtctctcg ttacagtgga ttgaagatgg 16740 ctaaatactc tcagcacagt gccgatcagc ttccctatga caagtctcca cttgaataca 16800 tcatggatac ttacaagcct aaatttcccg agagagaact tcagcaatgg cgcagcgttt 16860 tgggcaaatt cggtttgtct ggtcttcacc aaaccagtga aatccgtact ttatctgatg 16920 gcttgaaaag ccgtgttgtg tttgcagcac tcgctttgga acaaccccac attcttttac 16980 ttgatgaacc tacgaatcac ttggatatta cctctattga tgccctagcc aaagccatta 17040 acgtatggac tggtggtgtt gttttggttt ctcacgattt ccgtctaatt ggtcaagttt 17100 ctaaagagtt gtgggaagtt aaagacaaga aggttgtgaa attggactgc tccattgagg 17160 aatataagaa gtcgatggcc aaagaagttc aatctcgtga tactactgcc aaagttaagc 17220 atttgattta gttaatttat agatttttgg ttagggaata tgtgatacat tttgagtagt 17280 gggattaata taaaatgttt attacttatt tgaaagtgtt taagaagcgt attgcttttg 17340 gtctcatcgt tgtaattgtc aagctctatc attgagtgaa gctattaagc caaaatttca 17400 tctctgtgta ctgttcaaga attgtcgtta agtccgattt agagtggaat tatctttttc 17460 caccgactat aggtaaactg tacttctcag catttatgcg tgaaacttta tacagcatcg 17520 gttttgaaaa ctatgtacgc ttcttctcga aaagactaat aataacccat tctattaaaa 17580 aatgccagtg agctcgtaat ttctctagta ccttagaaaa cgctacacag caatctcgtg 17640 aattcacata gtaagcgcaa actgttgaga aaaatccagg ttagtaatca ataaataaga 17700 aatgcaaata ttctatatta ttaattgtat accagatcgc tatgctgttt acacataaag 17760 tcgatttgcc atagcttgtt agcaagctga tgatacgcaa gagtagcctg tcacctctgt 17820 aacggtctca acttaccaaa agcaacacac ggttagaaag acttataact tgctttttac 17880 tatatacaaa attccataat taatgtctat agatccagca aatgatagta agcttgctcc 17940 ggaggcgaat gacgctactc taggagacgt tgacagatgg atcgaacagt tgaaaaaatg 18000 cgagcctctg agcgaagctg acgttgaaat gttatgcgat aaggtaagtg aacactaagg 18060 agagtatata tgtgtatcag gcttggttgg atatatccca actttgcaag ttctcatttt 18120 ctcttgattt cttgagattg ttcagtttga tatgtttgag tttgaactat ccagcttatt 18180 tcggtttgat ttctaaaaag attaatatta cattaatgtc gggtttctag aaatctcatc 18240 ctataaatat atggtggtta aaaattacgt cggagactct catctatacc agcatttttc 18300 gtgttttcgc agtttttgct aaccattttt tctaggctcg tgaggtttta tgtcaggaaa 18360 ataatgtcca acctgtccga aatccagtta ctgtttgcgg tgatattcat ggacagtttc 18420 atgatctgat ggaattattt aaaattggag gtgatgtgcc tgatatgaac tatcttttta 18480 tgggtgacta tgttgacaga ggttatcaca gcgtcgaaac tgtaagtttg cttgttgcaa 18540 tgaagttacg ctaccctaac cgaattacga ttcttcgagg aaatcatgaa tctagacaaa 18600 tcactcaagt ttacggattt tatgatgaat gtttgcgtaa atatggatcc gctaatgttt 18660 ggaaacattt cacaaattta tttgactatt tccctttaac tgctttaatt gaagaccgta 18720 ttttctgcct acatggaggt ctttccccga gcattgattc attagaccat gtacggactt 18780 tggatcgtgt acaagaagtt ccccatgaag gtccgatgtg tgatttgctt tggtcagacc 18840 ctgatgatag atgtggttgg ggaatttctc ctcgtggtgc cggatacacc ttcggacaag 18900 acatttctga gacatttaat cacgcaaatg gattaagttt aacggcacga gcccatcagc 18960 tagttatgga aggatttaat tgggcacatg atggagacgt agttacaatt ttttctgccc 19020 caaattattg ttatcgctgt ggtaatcaag cagctatttt ggaagttgat gatacgatga 19080 atcaagtctt tttacaattc gatcctgccc cacgagaagg cgaaccggta atagctcgaa 19140 ggacaccaga ctacttcctt taaaagtttc aattctctaa tgagtgatca atcgattgtg 19200 attgtttcaa aaaatttatc cacctttctg atttttgagt taatactcaa gattaaaaag 19260 actactttgt acatcctccg catacgaatc ttcagactgt cttttcattt ccaggacttg 19320 tcaagtacct tttttgcaag gaaatcttaa aatccttata tgtattccac ttcaagccat 19380 tgcaaccgtg tcttatacgt acgtgaaata ttcttgttaa ttttgataag cacactagga 19440 tttttggttg tggacttatt tcttcgagaa atatctgcta tttaatatgt cgtgatagcg 19500 attaacgact gctgcatagt tggatggtat tgttttgaga caatattatg agttagaatt 19560 aggcatgctt aagcagtcat gtgctgtaat gaattaaaca tcctaaagct ttatgaccaa 19620 actttttaag ccagcttcat gattccatat ttgtagaagt ttgtctataa agaactttta 19680 aagaaaaaaa atggtttatt tgtctagata tttatttatt attgatactt gtcagataaa 19740 cctacaataa ctacatattt gaattgtaca acttttttat tcaagtataa ggggatactt 19800 ttgcatttca caaaccttga aggcaagaag agtactcaag gattatatat atttttagcg 19860 gtttaagaaa ctaccaccaa agggaaagta aagttacatt agactacgat aaaataagaa 19920 ccatctgact tgcatgaatc aggcgtcaca tacaaaatta ttgatttacg tcttggaata 19980 agagattcaa ggttgcatta attgagaatg agaagggggt ttgtatcagt aaatgactat 20040 aacaagaaaa aggaagtctg caattgccat cttgactgct gtataagcca aatggaccaa 20100 caaaggctat gagaaagtgc attggacaaa taaaaataag aagcaagtaa gacagcatat 20160 gacttgatcc ccaacaggct aaagaagaag taaaagagag gggagaaaaa ggagggagga 20220 aatcagctag gacaaaagtt tttgagcgaa ataaatttta tccgatgata attttgcttc 20280 cttcaaacgt ataagcagga atcgccaagt taagaggtgc aggaccacgg cgaatacgac 20340 cagagatatc ataatgagaa ccgtgacaag ggcagaacca tccgccatag tcaccagctt 20400 cgccaatggg tacacaacca agatgagtac agacaccaat cataacaagc cactcgggtt 20460 tttgaacacg gtcagagtcc gcttgaggat ccctaagagt gctaatatct acagaattgg 20520 cttcttggat ttcttcagga gtacgatgac ggataaaaac aggcttaccc tgccatttga 20580 cgacaaggtt ctttccctct ggaattttcg acaaatcaac ctcggccttc gacatagcca 20640 acacatcagc agatgcagac caactcgcca agaaatcatg aacagtagct tgagctccag 20700 cggctgtaag agcacccatt gtgcctacca tggcataaga tataacacga gaacgatcac 20760 cagtgctctt tgtttgatac tccgaaaagt ctggcatttc cggagagtca gtatatgtac 20820 gaatagaggt aaattttggg atggtcatca ttgagccctt caacgacgaa gcagtgcttg 20880 aaacgggaag caaccgtctt aacgaagatg ctaacgactt agaaataaat tgcttggcca 20940 gcatttttac aacgttttaa agagaaacag gttgttgaaa tattcggtgg gtagcggttg 21000 gggaagaaac gtcaagctgc ctctggttta aaaatggcgg cgtttgtggg tgctgtgatt 21060 tgctaagaag gttagttgta tttaccgaat tcaccgattg atgaaactac atatccgaag 21120 ttctccgaaa aataacgaag tacacaataa aaaattaaca taattttaca gctactttta 21180 acgatcagta cagtatagtg ctagactgtg cagtacatat atcatcacga atcgaaaatc 21240 ctatatcttt caaattccaa tattatggta cgctagagat cattttgttt tatcagatat 21300 aattttccag tctattttac taggttccgt ataagaacat agctggattt acgttcttcc 21360 gtccagctat aaactatttg gagattataa tattatccaa tatttagatg tttacagtag 21420 tatcattcat cactttacaa ggtacagcac ctgcataaaa caatacaaca gtattagatt 21480 gaaaattatc gtattctttc actagcctta attattttaa ggaattggta tatatcatta 21540 atcatagttc aatgtagaag aaatgcaata tacttatgta taatgtattc atgaagattg 21600 gtgacattta ttgaatatta agcgtatcct tcattaatat gcaggaaatt tttctactct 21660 attgaacatc atcaattcat aaaacgttct atcctcgtat tggtgttgcc ggccaatatt 21720 tgataggtaa tgcagtaaac ttgcgaaaaa tattatcaag tattttttct tcctctaaaa 21780 tttcataagc cgagtaatgg aactggtttt gatatatttc gatatctttc aattctttta 21840 atgagattgg tgtttttggg ttggtttctg gtttggaaga aaccattctc tccttgtcca 21900 gtgctttttg tcttaattct ttttctttta acaattgctc cttctccttt ttccacatta 21960 actccctttt ttccgattca cggaaccaaa gaatttgctc atctgttaac gttcgtatag 22020 tcccatcagg atagcgctct acactttgtg tatactcaac gtttgcactt tctgaatttc 22080 ccccacgatc gttttgcgcg aaagcaacat tccataggtt tactgctttt gcattaaaat 22140 gctcatcatg gaatttctgt aagtctcctt ctgtaatttc agaactcatt aaaagttccg 22200 tggttttaca caatattgga ttcagtaagg attactttgc tagttgtaac aagttgcgat 22260 gaaatcaatt tgatgaacga gcaaagctac gctagaacat ttaatgaatc acccaaatta 22320 aaatactgta tcgtagtgaa tttgataacc caattaaagc aaaacaaggt aatacgttag 22380 gattatacta acaacgcaaa cttacaagat gagtagtttc tttaagaatt tagcgatcct 22440 taatatttga tgtactttat ggaatggccg taagtatatt tttcttgctc ccttcgacta 22500 atctctcaga ctttgaccaa cttggagcct ttggcaacgt atgtttttca gatttccagt 22560 tacttttact aacattatag ggggactgtc atccttaaaa ctactcgcgg cgatatccag 22620 atagaacttt ggtgcaaaga agtgccgaag gcctgtagaa actttataca gttatgcttg 22680 gaagggtaag ttaaatcgtt gatgagcaac gttgtagtcc caaatgttgc aacattaaac 22740 tgcttcgggt ttacaaatat actaattaaa tacagttatt acgatggaac cattgttcat 22800 agagttgtac cagagttttt gatacagggt ggagatccta ctggcactgg aatgggtggt 22860 gaatctatat atggtgaacc ttttgctgta gaaacacatc ctaggttacg gtttataaga 22920 agaggattag tgggaatggc atgtactgaa aatgagggaa acaactctca attttttatc 22980 accttaggtc caacacctga atggaatggc aagcaaactc tatttggacg tgttgtaggg 23040 gataccattt acaatgtagt aaggatatct gagttagagt tagatgccaa ccaacgacct 23100 gtttttcccc caaaaataat ttcaacagag gtaattgaca attattttac tgacataaaa 23160 cctcgttcaa ctaaagaaga aagagagaaa attgccaatg agctagccca ccaggaaaaa 23220 cagaaagaaa gaaacaaatt attgaaatcc ggacgacgaa ataaagcagt tctcagtttt 23280 ggcgatgaag tcgatatgcc tattgtaaaa aagccgctca ggcagaaaac gccagtatcc 23340 agatcatctg atactacgac tgagttaagt aaagatttga tttcatcttc atcctcaatt 23400 cacagtactt actcgtctgc ccaaactgga ttgacctctg ctaaagtctc ttccgatgaa 23460 tatgctaggc aagtagacac tttagataca aagttaaatt cttcctctaa gtccaaggta 23520 caagaagaaa tttcccgttt gaagtctgaa cttcgtgact tagaaaaaag tggtggctct 23580 tcaaactcga aacccgtggt tgtacgtcct aaaaaacgga acatcttgac tgaggaactt 23640 gaaaagtata aaaaatccaa aaaagttgtc ttagggaagc gaaaaaactt ggagaatgac 23700 gaagagtcga cccttcgagc actttcatca tttcaaagca agattcgaaa tgcagaagat 23760 gaagatgtca tggatagtca atatggtagc aaaatagaag acacaccttg cagcttacac 23820 aatgttcctg gttgcttttc atgttttgat aggcttggcg aaaaaaatat aacagaaacg 23880 aacagcaact ggtttgcgca tcgattggtg gctgaaaatg atccaacaag aagaacggaa 23940 gaacttcgaa tacaacgagc agaagagctt aaagatgttc caagtgctag gcctaagaag 24000 cttttaatga aacgcgatat aatttaatgt tttacaaaga aaaaaaaacc tatgcttctt 24060 ttaagtataa attaatattt cacatatttc gtttgtaaat tctaataata attacatttt 24120 aagcaaagta tgggaatggt caattagtga cttgcaaagt aaacaattgt atttatcaca 24180 acgaaaaaaa actcgtatca ctataatttt taaacacgag gtgtgttgtg gaagaagaga 24240 aattattaaa aattcctgac aacttaacaa cacatttttt aagtgggctt gagtttggtt 24300 aattcagctt catccacact ttttttatca gtcaaaactt gaccaaaact accaagaagg 24360 ccaccagatg atttgaaagg acgtctcaac tcatcaatag caggcttatt ttgaacgtga 24420 atctgcactt cactgttatc aaacagacct ctagcagcag atacagactg taagagaaga 24480 ggaggagcgt agcccatata taaatgcatg aacaaagtgg tagcaattgt cacgagcatt 24540 tgtttaaaag atgtcaagag tttgctcaaa tcgtaatcac gcacggtggt agcgacaaat 24600 tttgaatgtt cacgtccaga catgggagta gcgggttcaa catattttaa aacagttaaa 24660 tctagaattg ttagagaata gatgaaccat ggtagattga attcgtttat ctacccattt 24720 tattaagaaa gacgaaacaa ccaatcttcc aaaccaacgt accgtttttc ttttcgataa 24780 taatcttcgt gtagaggaaa attcctattt gaactatatt cactgtagcg tatagaatcc 24840 tcaaaggcca aagtaatgag ggtcttgaga aatcaattac cctggtgatc atcatcaaga 24900 agatagagat accgattgat ttagtctatc atgttaacac ctgcccagcc aaatgttttt 24960 tcaaaatctt acttgaggat tattcttcaa tttctcccat cttgaaacca ttttgtacga 25020 agtgtagacg ttgaactcag actacctctc atacatttgg tgttgataat acactactga 25080 aaggtaacat gttaccatac atttctgcct agctatattc tgttactata cttttaagag 25140 ccaggatttg gagttttttt gcaatagaat tgagtaagaa aagacgtaga attatttttt 25200 ttcttgaaag tgccttctat ctgatccaac ttggcaagcg acgcatctct ggtgaacgaa 25260 tgttggaaaa ttagagttgt ttaaacatga atgccttgcg ctaataaggg atttcctgca 25320 gtaacaaatc gtagtgctat tgcatgagaa tgcctaagac tcttaatttg cagaacgaaa 25380 aaaatgtttc tgcattcact aatatgataa gttgtggttc acttacatag aaatacaacc 25440 cagtttcagt tttatttatt ttgcttacaa tttaaaattt agccctgaag cttttgtaag 25500 ttgtttatca ctcgcatgtt tgtggttaaa atacattttt accacgattt tgaagaaata 25560 gtacattagc aaaatgtgaa atcaattgtt aaaaaaaagt ttatcgtttt tttgacaggc 25620 attagtaact acgaatatgt tgtccaacaa gcccaaagtg aaagaatact caattttata 25680 ttttgtagta tgcacttctc tattctttat ttattttatt gtgagttcta atgaaagtaa 25740 ttttttgtag gatagaaaaa ttaaataagg taacttagtg taataaatta atgctctagt 25800 tttatcgcgc agggacttca aaattaataa tagctggcga acttgctatt tattctattt 25860 gtatgggatt gtttttctcg cttcttttaa gcccataatt agaatcgatt gctaacatgc 25920 caaccctaat gcaactcagc aacgatatga aaccattgac atttgtggag gccttacgaa 25980 atttcaagtc tgccaaggta tgtaatagaa aaactggtgg gttttaacaa ttggtcaggt 26040 ccttttagtt ggagcgggtg gaattgggtg tgaattgtta aagaaccttc ttatgtcagg 26100 agttaaagaa gttcatatag taagtgagtt gtatatttaa attttttaaa ccttaagaaa 26160 cgtttcgtct acatgttttt atcgcgattt attaactctt atactgtaga tcgatcttga 26220 tactattgat ttgtctaatc ttaacagaca atttcttttt cgtaaaaagc atgtcaaaca 26280 acctaaggca atcgttgctg caaaaaccgc aagctcattt aacccaaatg taaagcttga 26340 agcttatcat gcaaatataa aagaagaccg atttaatgtt gcttggtttc gtcaatttga 26400 tcttgttttt aacgcactag ataacttgga tgctcgtaga catgtgaata aacaatgctt 26460 acttgcttct gtacctttga ttgaaagtgg aacaaccgga tttcttggcc aggtacaggt 26520 tatcattcat ggcaaaactg aatgttacga ctgtaatccc aaagagcctc ctaaaactta 26580 tccggtttgt accattcgaa gcacaccaag tcaaccgatt cattgtgtag tttgggcaaa 26640 aagttatttc ttcccccaac tttttagtaa tgatcaagaa agtgatggaa tcattgacaa 26700 tgtttctgca aacgaaatgg agagacgtga aatcgcagaa ctagctagag aaacaactga 26760 gctaaacgag cttaggtcgt caattggtca aagtgacaat ggttttgaaa aaatatttac 26820 gaaaatgttt actaaagaca tagttcgact ccgcgaagtc cctgacgcat ggacatatcg 26880 ttctcctcca aaagaacttt catactcgga acttttagag aatgccgaaa aagccacttc 26940 accttggctt aatgaacaaa atgtttggaa tgttgctgaa agttttgcag ttctcagaga 27000 tagcattaga cgccttgctt taaggtctaa atcctcaaaa gacgatcttt cttttgacaa 27060 ggatgataag gatacattgg attttgtagc agcggcagct aatttgcgtg cccatgtatt 27120 tggaattcaa caactctctg aatttgacat taaacaaatg gctggcaata ttattcctgc 27180 tatcgcaacc acaaatgcag tcatagctgg actatgtatc acgcaagcta tcaaggttct 27240 tcaaggagat ctcaatgatc taaaaaatgt aagttattag gtttcagctg tatttgctaa 27300 caatttaaga tatacttggc taaaaggcct accagagtac tccattgcga gaaaacttgt 27360 aaacctaacc cttactgtcc tacttgttct tttgtacttt tacagcttgg agtaaatgac 27420 aaaaatatga ctctaagagt tcttgttgat gatattttga aaagtcgttt gcattactca 27480 gaagaggtta gcgttttaaa cgataagctg atatatgatc ctgactttga tgataacttg 27540 gataaaactt ttgatgattt gggtataaat cctgccaaaa atactattct cacagttctt 27600 ggtgattctg ctgtcgaaaa ggatgatgat ggcgaggaag ctactagggt tcccttgtta 27660 attgaagtta cattcattga ttctaattcc accgaaggat taccttacca aatactttca 27720 aatgctacca gcattcctct taaacagcaa cctccttcaa attcgccaga agattcacaa 27780 gttttaaccg acgagattaa tgaagttaat gacttctctt cgtcggaaag aatcgttatt 27840 aatcttgatg aatatgacat tattgtcgat tctaaaacta gcagtcataa caaacaactc 27900 aaacgtcgac catctaacga tacacttact caagaagcaa aatcgaaaaa gcaagcgaaa 27960 atacacacta tgtaaataaa ccatttggat atttactgca ctcaatacta gatatcttac 28020 taaaatctta catgtcaacg ctagcttttc atgtcggtca aaatcaaata ttaaaaacct 28080 attatcgtta tagaaaaata ataatcagtc tataataatc tctgtcgaaa atagttattt 28140 cactcaagta aacatatata actcaaaaaa aagacctagc gaaatcgatt ctcaagtgac 28200 caaataatta aaaagtcgta ggataaaaac ttacatctct aactctaaag taactgttag 28260 gaccaatttc atacgaacgt tgagaaaaga gttccaggat caaaacagaa accaccacaa 28320 ggataaccca aaccgtaatc tagccattta tttaatcagc aaaggtcttg ccggccaaga 28380 tgttaaccaa gttgtgcata tcacgccacc aagcgttctt aggacgacgc atctcaattt 28440 cggtttcgtt gttctcaaca tcagcaacag agctgaaaga gacaccagta ccacggatac 28500 cgatgacaac ggcagagctg gggtcattac ccaagtcgtt ggcacggcaa gtttcgaaga 28560 aacgaatggc acgcatagcc agacgagcag cacgagcacg gtccatagga gtggggttac 28620 caccttgttg aacgtgaccg ggaacagcgg tacgagcgga gaagcgctta tgagcttctt 28680 cactgatgat gtttccaata acttcggtgg tgtaaacctt agaagcacat tcgttacgaa 28740 ggataagttg accagcacgg ttacgaccag cttctaaggc gaatgtagcc ttaaggtgat 28800 caatatcctt acgcaacata tccaaggaga taccatcctc gggggtgtaa atggcggagg 28860 caccagtaat gagaccaccg acagtagcga tataaccaga gcggccacct tgaacttcac 28920 aaacgaagac acgacgacgg ctagcactag cactttgctt aatggtatca cagtattcca 28980 taacggcatt aagacaagta tcgcaaccca aagagaattc ggtaccggga acgttgttgg 29040 aaatggtggc agggatgata gccatgggaa tgcggaatga agggtagtta acacgtgcac 29100 tctcaagttg agaaagggcg gtgaaagcct cgaaaccacc aataataatc aaagcatcaa 29160 tcttatgttg ttggaacttg aaggcagtga agcccatgtc gagatcaggg gtatcacggt 29220 tggtaccgat ttcactacca ccacgaatgc accactcatc aacatcaatc catgaaagtt 29280 catgaataga atcatggcgc aagaagccag agaaaccatt gtcaatggca agaggagtgt 29340 gaccacggtt caaacaatat cgaacggcag cacgagtagc agagttcata ccaccagcgg 29400 gagcaccaac atggatgatg gcgacacgca ttctctcgtc cttgggaacg aagtgtgact 29460 cgtcttcaat aaaggtagta ccttcccaag tgtgtaagta atcagcaaat tcggggtcac 29520 ggagctccat agcatgagcg aactgcttct tctcaatagc atcagcaacc tcatgagtca 29580 acttaacagc ctccatcaaa ggcttgcggt taatcttgtt accattgata gcaatcatgg 29640 gagatggagt atcaggggta gaggcaagaa cagcatcaac ggcatcaaca ccttgaaggg 29700 tagcaagcat acggtcataa gcacaaggaa taccaccacg ttgaacgtga ccgagagtgg 29760 tgacacgagt gtccaagtga aggcgctcaa ctaacaagtt cttgatgtct tcgggagaaa 29820 tgtggttaag ctcggagtca atagcaccct ctgcaacaat aacaattgac tttctcttgc 29880 ccaacttacg gacagagctc aaagaattgc acaattcgtc ttgccatttg ccgacttcag 29940 caggtctctc agggataaag acgaaatcag caccggtagc caatgcagct aaaacagcca 30000 accaaccgca atgacgaccc atgacttcaa cgatgaaagc acgagaatgg gaaatagcag 30060 tagaagaaat ggagtcgacg gcttcgcaaa tacggtgaag agaagagaag gcaccgatag 30120 taacgtcagt tgaagacata tcgttatcga ttgaaccgac caaaccgaca atggtaagat 30180 ggcggtagag cttggcttgc tcgggagtaa tagccttggt gtcctccaac tctttaacca 30240 aaccgggcca gtcagaacgg aagatatcag caccggtcaa agaaccatca ccaccgcaaa 30300 caataatgga atcaatacca gcggaaataa ggttcttggc agcacgaaga cgaccaggac 30360 gctcacggaa agccatacaa cgagcggtac caataagagt accaccctca gcaagccaac 30420 cacggacatc accccattgc aattgcttga tcatatcacc accttgaaca agaccttcat 30480 aaccttcata aatagcgaaa gcatcacaac cacggtgaat ggcaatacga gcgacggcac 30540 gaacaacagc gttcatacca ggggagtcac caccactggt cataactgca atcttcttct 30600 tgacacctgc aggcttgtca gaagtggtag ctttcttgag agtctcaacg acgggagtag 30660 ccaaaccgct ctcgaggtta gaagcagcac cagactcctc gctcttctta aggttagcat 30720 gggcgaaagg attgtaacgg tcggagaagc caatcaaatt acccaaggga tcctcgacat 30780 aaacctcatc aggcttcttc tcgttgggga aagcttggta tttaatggca tcggcactga 30840 gttgcttaag caagtcaagc aagttgggat agtaaaaaac aagagaactc ttttgtccgc 30900 gccattcaga atcttcggca gcgggggaaa ggctcaattc accggggact aaacggaact 30960 tgatggtgac gctttcagca gagttgtttc cagcgacatg catccagtcc tcacggagag 31020 actcgttgca aacacgggca ttgtcagaat cgctggtacc gaagctggca accttcttga 31080 agccaagctt ttggtagaag tcgagagtct gattatatgt gtcctcagtg tttgcaacaa 31140 cagagtagca cgaaattcca tgcacggttt ctccactcat ttttcaatgt atatggttgt 31200 gatcaaggaa atttctgtgt ctttttctta tgttattaag aaacgtcttc ttgtgtggtt 31260 gtgggtagat gtgggttaaa gaagagttat cgtgcagcga tggatagtga gtgtgtagta 31320 taagctgtat taaaaaggta aaaatctttg gtgcctaagg aattaataga aaaatggaat 31380 atgcttccta cgtccggatt atattcaatg tcactccaag tggaaaaaag cgctaccgtt 31440 gccgtggtaa ttgagatacg tagaacgcga atgtccgact gcttccgcga tccgtcagtg 31500 tacacgtcaa tcattatcat agatgagtgt caacttggcc aattatagca atagcagcta 31560 tcatctttcc acctcgttaa cttatgccgt acgaagcgcg tttttcgact accgtatctt 31620 gaggactttc gcataaggca aatgaatggg acatatcgag tgcagaatgg ggattcaggt 31680 agcttgggca catacacaca aacggctaag actgacggag agaggcaaag tagaagaaga 31740 gacggattga aagacgggaa gtttttggcg attcagtgag attttaaatg gataaaaaag 31800 acagcacatg gaaaattaac gcgagagaag agacttgggt gcgtttctga tgttgcacga 31860 agcatggcta tgaagtgcaa gcaattaaca agccaacgaa cgattaacgg ggtttgagtt 31920 tttgtcagtt gagctaaatt gatcttcaat tcatccgtca aataacaatt caaataggta 31980 gccggtgcta atctggcatc cccttttctt ccaggtgtta acgaaggtac cgaaatgtaa 32040 gtaccgaggg tatcacagac acggatgctt ctagataaag ctttgcttag gaactgatat 32100 ggctgacccg caagtaaata aggctaaaca ccaactagca cggattagac gaagcagtta 32160 acaagattcg ttgcaattgt atacagtaaa gatatcaagc aatatgccgt tggtttggtt 32220 gcgtttttcg cgtcgctagt gaatgcgagc aaaccgtttg gaaaaggaat tgggacagat 32280 ggttaaacat taggatacta cacgaaattg aataactttt gttttacttt tttctatact 32340 gctacatgtt tgatttatga gcgttcactc ttttcttaca tagacgagac gcgttcttgg 32400 taaggtcaat gcgctcgtgt cgaaatgttt ataccagctg agttccctta tgtctggcgt 32460 gcacgtgtaa taaaataatt gtaaaatgta ttttaattat tttttattca aattagtgta 32520 ttattaaaga ttgtatgcaa ttaagtgtag aacaattgaa tctcatccgt gtttcgtgtc 32580 ttcctctaca tgagcaacgt gcctagggcg aatttagcta cacactagca atggctctaa 32640 catattaaca tctcttacta cactatggtt cactggtttt aaccttacaa caagctctaa 32700 cccaactgta acttataacc ttacaatggc tctaacctga cagtagcttg taacctaata 32760 gcggctcgtg aacctaccat aactagtgtg ctttgttaca aatcggtgaa taaagtaatt 32820 ttactattac cgtttaggaa catactcata caactgctct tcggcgttaa tattgcggtc 32880 cgacacgttg gttaataaaa ctatctcctc cgggatttcc ttgctgtagc cattacgata 32940 tgcgacgttg attcacaaga tgttgcatta tagcatcctg acttgaacca cctgcaaaaa 33000 tttttttcat tcttaggcgt ttgtttattt actcaccacc cacaggtgat aatttgctat 33060 tcacgttgca ctgctttact taccgaacgg atcaattcca catagcgaga gatatcgtaa 33120 acggcaaaca atgtctgaat tttcatatga gttattccac attgtcagct ctatctactt 33180 tgatggatca caagttttcc cggattttag ggttgctcaa taagctaaca tcggtttcgg 33240 cccatgaatg atgtccagcg catggtttct cgtttgtgtc gcaacaccta gtcctgaagt 33300 agctgagtga gtgtataagg tacagaaatg aaatgaagtc gtgagatgaa tacacaatca 33360 tgagacatac ttggcgccac gttgagtaat tgaaatgatt gaaccttttt tgacggttgg 33420 ttgagcagat tgattattga ggttttattt attaggattc attatgtagc gcacaggatc 33480 aaatactagg ttgtgcaata ctactcgaca ttgcctcaat tcattacttt cgctagccaa 33540 aaaaacaata cgggctaatt ggaagttaaa cgtgccataa atttcgtcct tgttgaaata 33600 ctgacgtttt caaagttacg catagcttgt ctttgattcc ttatatacaa cattgtgcag 33660 tttctgttga atgtagtgaa accaagcgat gaataagctc aaaacatgaa aatttttcgt 33720 ttcatttttt tttgacagga ccgtatcagt gtcgcagtaa aatgggatcc taagtatgca 33780 aaaacaagca gttagttaga caatttatgg ttgcgtattg ctgctacctt cgcaatcggc 33840 acaatattca agcaatttga aagcgactga atgcccgaat ttcattggct atatgatgaa 33900 aagcgaaaat cctactttga cgaactataa agtataatat tcagcggcaa tgttgtatta 33960 aacagtagaa aggtttatta aaggtttatt aaatgtttat ttactcaatt gatcattgtt 34020 gaaatttgct tttgaaaatc attggcgtag attctcgtgt cgatgaaatg tatccctaac 34080 aaacgcaaaa acgttttttc aatgcctaga aattgaagtc gttgaactac tactacagca 34140 aaatgccaaa tctgtttact taactgatta aaagtgaaac gatactgaat acttttgatt 34200 tttcaaataa atttggtagc atatgatcgg tttcttgttc tttttcttta aaaattggaa 34260 atctaaatgc aaacgaagta atattaatag tggtaaaaat attaataggt atggaacttg 34320 ctattttata aggctgcttt attacttgaa tccatcaaac ttctcacttc actgaacagt 34380 tttgccatgc tctcacgaaa actcctaaat taccaaacct gttttttata taaacacgcg 34440 aattgctgga tttggatcct atcagcttca agtacttaat tcatcagcgt tcaaaccctc 34500 ttgtattaac agtctaccat ttttattcat caaatatttc tcgctttatt tccatatatt 34560 atgttatgaa tatttatcga ttgtcagcga tatataacgt agtaaattct tagtgtatac 34620 acttaccgta aacacaacaa aactctttct cagcagtcaa tcttcgtacc gtccatttct 34680 agtgtgttta tcttggtatt gtatccttta ttgtttgtga aggaattttc cagtattgga 34740 attggaatga tacctcaaga aaggtatact ctgctagggt aggatcaatt acatacattg 34800 tgtgtatagg tatctgtttt cacataaaaa aggcgtcaac gataattcgt ctgttattaa 34860 taatttatac attcgcataa agcgatcaaa aaggcattca attacagaat cctacttaag 34920 cttcactttt ttgaatacga acactaattc aaattctcgc cttccaatac tctcttttca 34980 atttttgtct ctctttttac atatttattt atcactgatt cgtttgtata tttttctttt 35040 aattttcaaa tagcctttta tacatcaatg tttactaata caccggttgg agggaaaaga 35100 gagcgtcaaa atggcgctca tccagcttgg tcgacgttag gagcgaactc tgctcagatt 35160 catcaaaata cggctgattt ggcctccaaa atgcataaac ttcgctatac aaagataagg 35220 tcccctccta ccagggtgtc cattgaatca attactccta aacaaagatt tccagctccc 35280 aatttcgaac aggcttacca ctctaatatt cgatacgagc aagaggaatc tgataacgaa 35340 gaatttgaaa acgtagtgaa aaatggacac gaagcttcga cgaatgtatt ctatgaatca 35400 gatggagatg atgaagagtt tgtcaatgaa gaatacgaaa acagcatcga cgaggaaagt 35460 gatgatgaag ggtatagctt gaacgaggat accaccgcaa caaatgccag ttttaggtac 35520 ccgatgaatc aaagatctac aaggaaatct caattttatt cctcaaaatt taaaccatta 35580 ctttggttcg gtatcactct cttttcgact ctcctaataa ttactctact tcacaagggt 35640 caagaatttt actcaagatc 35660 //