ID SPBC1539 standard; DNA; FUN; 19920 BP. XX AC AL096874; XX SV AL096874.1 XX DT 22-JUL-1999 (Rel. 60, Created) DT 22-JUL-1999 (Rel. 60, Last updated, Version 1) XX DE S.pombe chromosome II cosmid c1539. XX KW acyl-coenzyme a binding protein; ADP-ribosylation factor; KW amidotransferase class-I; anthranilate (PRA) isomerase; KW anthranilate synthase component II; argininosuccinate lyase; argx; KW conserved hypothetical; formaldehyde dehydrogenase; Glutamine; KW Indole-3-glycerol phosphate synthase; trp1. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-19920 RA Mc Dougall R., Rajandream M.A., Barrell B.G., Seeger K., Quail M., RA Harris D.; RT ; RL Submitted (22-JUL-1999) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk XX DR GOA; P50514; P50514. DR GOA; P78870; P78870. DR GOA; Q92370; Q92370. DR GOA; Q9Y7Z2; Q9Y7Z2. DR GOA; Q9Y7Z3; Q9Y7Z3. DR SPTREMBL; O94614; O94614. DR SPTREMBL; Q9Y7Z1; Q9Y7Z1. DR SPTREMBL; Q9Y7Z3; Q9Y7Z3. DR SPTREMBL; Q9Y7Z4; Q9Y7Z4. DR SPTREMBL; Q9Y7Z5; Q9Y7Z5. DR SPTREMBL; Q9Y7Z6; Q9Y7Z6. DR SPTREMBL; Q9Y7Z7; Q9Y7Z7. DR SWISS-PROT; P50514; ARLZ_SCHPO. DR SWISS-PROT; P78870; FAH1_SCHPO. DR SWISS-PROT; Q92370; TRPG_SCHPO. DR SWISS-PROT; Q9Y7Z2; ARF2_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c1539 is overlapped at the 5' end by cosmid c244 and at CC the 3' end by cosmid c1289. XX FH Key Location/Qualifiers FH FT source 1..19920 FT /chromosome="II" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c1539" FT /map="IIR" FT misc_feature complement(1..108) FT /note="nominal overlap with cosmid SPBC244 S. pombe FT chromosome 2" FT misc_feature 3..77 FT /note="CDS contained within cosmid SPBC244 S.pombe FT chromosome 2" FT CDS complement(288..920) FT /db_xref="SPTREMBL:Q9Y7Z7" FT /label=SPBC1539.01c FT /note="SPBC1539.01c, len:167," FT /gene="SPBC1539.01c" FT /product="hypothetical protein" FT /protein_id="CAB51333.1" FT /translation="MLTRHCNRLGLQIENKFVFRSSSWNCVRRIGKIACNENKYRYEMT FT STEEDIDSFFSRVFGEKNYISDKSLREQIVTHKSYKHGLKRYNEPFVSVGNAVIDVCLL FT NHYLESGNFSTIPSYKDLVNLRSPARLAEVAKKWNPETATQCILPLKGPNSPSSSSFEK FT IYSSIVSGLVAVVYFQKGGVEAMNFCKKSIISDLTKDFVRPNTVHNQ" FT CDS 1254..2414 FT /db_xref="SPTREMBL:Q9Y7Z6" FT /label=SPBC1539.02 FT /note="SPBC1539.02, len:386," FT /gene="SPBC1539.02" FT /product="hypothetical protein" FT /protein_id="CAB51334.1" FT /translation="MNQDDFRKLLATPKAETSQLKNFSSNKSQRLVFGRKHKTAKLEAP FT RALIKRKQLSHSTSSDITRHSNAKNSGKDTQFYEEPSSKQDIELHKLHEKLRNGQITTK FT EYSEKSKELGGDLNTTHLVRGLDRKLLEKVRSNELALDDSLLSSSEKEVDEEADKLLEK FT VAEESSHPESVSILEEKKKIPLYPNGQPKYRKILENGKKVKYLLDENGEILKRLVKKEK FT KLKNDNERLENEHRTEKLNVNANSLGKSFVKHDIPLPPVDLKLDIFEEVGEYDPFHEND FT KEPAELKAKDAFQLKGHHELDAPYHKKVFDTNQYSDLKPTNFMSQIHRLAKVQERKEEE FT ERKKGKDGQIVDAGFGLVLSKDDTADIHELGESDDDDNVKRRKTKG" FT CDS complement(2623..4005) FT /db_xref="GOA:P50514" FT /db_xref="SWISS-PROT:P50514" FT /label=argx FT /note="SPBC1539.03c, len:460" FT /gene="argx" FT /gene="SPBC1539.03c" FT /product="probable argininosuccinate lyase (EC 4.3.2.1)" FT /protein_id="CAB51335.1" FT /translation="MASSQKLWGGRFTGATDPLMTAYNESIHYDKRMFNADIDGSKAYA FT KALEQRGIISADELDKMLDGLEAVRDEWKTNKFTLQPSDEDIHTANERRLGEIIGTGIA FT GKLHTGRSRNDQVTTDMRLWLRDELDIIQKSLVGLLQVFVARAESDLDIIMPGYTHLQR FT AQPIRWSHFLLSHAFSILNDLDRLKQIYSRVNRLPLGAGALAGNPFAVDRKFLQKELGF FT EGVIMNSMNAVADRDYVIEFMFWASMVMTHISRLAEDLIIYSTSEFNFVTLSDAYSTGS FT SIMPQKKNPDSLELLRGKSGRVFGNMMGFMVSVKGIPSTYNKDLQEDKEPLFDSSKTVL FT DSIQILTGVLSTLTVNPENIAKSLTADMLATDLAEYLVRKGVPFRETHHISGSAVRMAE FT ERNTTIDKLSVEDFKSLHPLYEEDVADVFNYESSVEKRCAIGGTAKSCVLEQIQTIKKA FT LE" FT misc_feature complement(2701..3978) FT /note="Pfam match to entry PF00206 lyase_1, Lyase," FT CDS join(5627..5686,5873..6652) FT /db_xref="SPTREMBL:Q9Y7Z5" FT /label=SPBC1539.04 FT /note="SPBC1539.04, len:279, SIMILARITY:Saccharomyces FT cerevisiae, Q12164, chromosome xii reading frame orf FT yll023c., (279 aa), fasta scores: opt: 390, E():8.4e-20, FT (30.0% identity in 250 aa)" FT /gene="SPBC1539.04" FT /product="hypothetical protein" FT /protein_id="CAB51336.1" FT /translation="MEPKQRVVKPLKERVLPVVKNTQFVWFSGQVIVLISSVLYALQAI FT PFRSAPPFLFKSAAFGAIVAYAIVLYKTYSPNLTSRASWNKHFFARLMLDDNVQYFILA FT LSMLIDRPILFSLAPYAIYATFHISTYLRSVLLPAIYPNISDAKTASYASRVSNLLNQY FT TRSQFQPAMQLVASLETFLLFRLFFGVFLRKNSISRLVGYIFFLRMRYTNSHFTRASIK FT AVSLRMDRLVADNRVPPVIKNAWHTFKTYVSKFGASPVGTAQSRPTASSSTTAPSST" FT misc_feature 5687..5692 FT /note="gtaaat, splice donor sequence" FT misc_feature 5856..5872 FT /note="ctaaccgtttattatag, splice branch and acceptor" FT CDS join(7238..7306,7349..7750,7801..7971,8012..8149, FT 8205..8435,8479..9015,9057..9716) FT /db_xref="SPTREMBL:Q9Y7Z4" FT /label=SPBC1539.05 FT /note="SPBC1539.05, len:735, SIMILARITY:Saccharomyces FT cerevisiae, YEY7_YEAST, hypothetical 92.5 kd protein in FT bem2-ncb1 intergenic region., (801 aa), fasta scores: opt: FT 248, E():5.6e-08, (25.0% identity in 671 aa)" FT /gene="SPBC1539.05" FT /product="hypothetical protein" FT /protein_id="CAB51337.1" FT /translation="MFDQLEFYPAVNYEDNETQNDIKLPEVAKLENIETVHSISKERRD FT SLTEILNDSSSLPARPFSLPNPNNSTVEKQSLFPFEEKMNPIWIISRPTFSIEQDAEKK FT INELQTFTNIIDQILGQTNNIESTLLSMKEKFESSEKKLSEFSEMCENLSTDEMRFSEI FT ADGIRKGLTIFAPLKELTRVFRHPPPDFAGKVSFKEHITQLNTCIMFLEENLDFQESPH FT YLGQYKKLLSQAMDIFKPYFIRIIKQTTDQVLKDSKKMDVHKQLHSSLFYARFSAVGHN FT LCPTITELCKLCSKESLDAFLPAFYDVYFQCRTRLLKPVLDYHLKSFFMEKSISSYIQK FT SLALLQLTFFDENKLFREILIMDDFRFMHYWNNLCQSFFENSRSLILHEKNLTELCEVC FT SYIQSFQNAILEGEREDVDKKVVEFLNPLVLELQERLLFVVQTAIETDIQRYSPTEEDL FT NPIADDKSLLFDLEKLRLNNDEEKLDPDVPQKLAMAQGWYPVVQKSLIILSKIYRLVNS FT QVFDEIALELVHSCIRSLVDAYRYFSRNNDKQLARLFLIKNFLVLKDQLNSFDIHYACI FT EAGVDLRKVWDSVREWRSNLRGVLQLVYETFPKFITNAVDTRQELNQQLRVAVNGYIET FT AVIHYTECLSIGNLESITEFQNRIQKFPELRQQISLYLSETWIIELFLQAIREEVVSKF FT QNFYESIVANEDITGSDHNKSGTTSLKHLNEYVEDIYSVMS" FT misc_feature 7307..7312 FT /note="gtaagc, splice donor sequence" FT misc_feature 7336..7348 FT /note="cttacccaattag, splice branch and acceptor" FT misc_feature 7751..7756 FT /note="gtatta, splice donor sequence" FT misc_feature 7785..7800 FT /note="ctaacaccttgaacag, splice branch and acceptor" FT misc_feature 7972..7977 FT /note="gtacga, splice donor sequence" FT misc_feature 8000..8011 FT /note="ctgactttttag, splice branch and acceptor" FT misc_feature 8150..8155 FT /note="gtaggc, splice donor sequence" FT misc_feature 8190..8204 FT /note="ttaacaactatttag, splice branch and acceptor" FT misc_feature 8436..8441 FT /note="gtatgt, splice donor sequence" FT misc_feature 8464..8478 FT /note="ctaatgataccgtag, splice branch and acceptor" FT misc_feature 9016..9021 FT /note="gtacgt, splice donor sequence" FT misc_feature 9043..9056 FT /note="ttaacagtttttag, splice branch and acceptor" FT CDS join(10155..10232,10290..10475) FT /db_xref="GOA:Q9Y7Z3" FT /db_xref="SPTREMBL:Q9Y7Z3" FT /label=SPBC1539.06 FT /note="SPBC1539.06, len:87, SIMILARITY:Canis familiaris., FT G1478487, acyl-coenzyme a binding protein, acbp., (86 aa), FT fasta scores: opt: 318, E():2.7e-17, (59.8% identity in 82 FT aa)" FT /gene="SPBC1539.06" FT /product="probable acyl-coenzyme a binding protein" FT /protein_id="CAB51338.1" FT /translation="MSSTFEQAAADVKELKETPNSDELLKLYALFKQATVGDNNTEKPG FT LLDLKGKFKWNAWEELKGKSKEDAASEYISFVDELKTKYGMK" FT misc_feature join(10167..10232,10290..10466) FT /note="Match to PF00887 ACBP, Acyl CoA binding protein FT Score 142.40" FT misc_feature 10233..10238 FT /note="gtattt, splice donor sequence" FT intron 10233..10289 FT /note="confirmed intron" FT misc_feature 10273..10289 FT /note="ctaatttgttgtactag, splice branch and acceptor" FT CDS join(complement(12281..12313),complement(12080..12123), FT complement(10913..11972)) FT /db_xref="GOA:P78870" FT /db_xref="SWISS-PROT:P78870" FT /label=SPBC1539.07c FT /note="SPBC1539.07c, len:378, SIMILARITY:Pichia pastoris FT (Yeast), O74685, formaldehyde dehydrogenase, (379 aa), FT fasta scores: opt: 1687, E():0, (62.3% identity in 379 aa)" FT /gene="SPBC1539.07c" FT /product="probable formaldehyde dehydrogenase" FT /protein_id="CAB51339.1" FT /translation="MSFEGKTITCKAAVAWGAKEPLSIEDIQVAPPKAHEVRVKVDWSA FT VCHTDAYTLSGVDPEGAFPIVLGHEGAGIVESIGEGVINVRPGDHVILLYTPECKECKF FT CRSGKTNLCSKIRETQGRGLMPDGTSRFSCRDKTLLHYMGCSSFSQYTVVADISLVAIS FT HSAPLRSICLLGCGVTTGFGAVTHSAKVESGSTVAVVGCGCVGLAAMQGAVAAGASRII FT AIDINADKEVYAKKFGATDFIDSSKVKDLVQYVIDVTDGGVDYAFDCTGNVTVMQQELQ FT FCHKGWGKLCVIGVAAAGKTLDFRPFLVVTGRQVLGSAFGGVKGRSELPNFVDEYMQGH FT FKVDEYITNEEPLKNINKAFDHMHEGKCIRCVVDMNKP" FT misc_feature join(complement(12080..12123),complement(10928..11972)) FT /note="Match to PF00107 adh_zinc, Zinc-binding FT dehydrogenases Score 573.22" FT intron complement(11973..12079) FT /note="confirmed intron" FT misc_feature complement(12074..12079) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(12124..12142) FT /note="ctaataacattcgttttag, splice branch and acceptor" FT intron complement(12124..12280) FT /note="confirmed intron" FT misc_feature complement(12275..12280) FT /note="gtatga, splice donor sequence" FT CDS join(13095..13200,13300..13330,13533..13605,13661..13859, FT 13903..14048) FT /db_xref="GOA:Q9Y7Z2" FT /db_xref="SWISS-PROT:Q9Y7Z2" FT /label=SPBC1539.08 FT /note="SPBC1539.08, len:184, SIMILARITY:Gallus gallus, FT ARF6_CHICK, adp-ribosylation factor 6.adp-ribosylation FT factor 6., (174 aa), fasta scores: opt: 897, E():0, (75.6% FT identity in 172 aa)" FT /gene="SPBC1539.08" FT /product="probable ADP-ribosylation factor" FT /protein_id="CAB51340.1" FT /translation="MGNSLFKGFSKPFSRLFSNKEMRILMLGLDAAGKTTILYKLKLNQ FT SVVTIPTVGFNVETVTYKNIKFNVWDVGGQDKIRPLWRHYFTGTKGLIFVVDSADSNRI FT SEARQELHRIISDREMRDCLLLVLANKQDLPGALSPAQITDVLQLDKLKDRLWNVQPTC FT ALTGDGLLEGLAWLSQNAKLK" FT misc_feature join(13116..13200,13300..13330,13533..13605,13661..13859) FT /note="Match to PF00025 arf, ADP-ribosylation factor family FT Score 300.39" FT misc_feature 13201..13206 FT /note="gtatgt, splice donor sequence" FT misc_feature 13288..13299 FT /note="ttaacattttag, splice branch and acceptor" FT misc_feature 13331..13336 FT /note="gtaaag, splice donor sequence" FT misc_feature 13522..13532 FT /note="ctaacagccag, splice branch and acceptor" FT misc_feature 13606..13611 FT /note="gtatat, splice donor sequence" FT misc_feature 13646..13660 FT /note="ttgatttgtttgtag, splice branch and acceptor" FT misc_feature 13860..13865 FT /note="gtaagg, splice donor sequence" FT misc_feature 13888..13902 FT /note="ctaacactatggtag, splice branch and acceptor" FT CDS complement(14459..16738) FT /db_xref="GOA:Q92370" FT /db_xref="SWISS-PROT:Q92370" FT /label=trp1 FT /note="SPBC1539.09c, len:759, identical to, TRPG_SCHPO, FT anthranilate synthase component ii, except for a single aa FT difference at position 387 (Q-E)" FT /gene="trp1" FT /gene="SPBC1539.09c" FT /product="anthranilate synthase component II (EC 4.1.3.27)" FT /protein_id="CAB51341.1" FT /translation="MSEKVDVGESVKGDASENAVKEVAERPIVMIDNYDSFTWNVVQYL FT SNLEKRYPIMVFRNDEITVDELEKLNPLKLVLSPGPGHPARDGGICNEAISRFAGKIPI FT LGVCMGLQCIFETMGGKVDSAGEIIHGKVSKINHDGLGFYQGIPQNISVTRYHSLAGKI FT SSLPDCLDVTSWTENGVIMGARHKKYAIEGVQYHPESILSEYGKEYIQNFLNLTAGTWE FT ENGIVMPTKNNAFNAAMRENSNSVSSTKIRKQESILEKIHAQRLIDIAESKRKPGLSVG FT DLQTYLNLNIAPPCINFYERLKQSKPALMAEVKRASPSKGDIKLDANAAIQALTYAQVG FT ASVISVLTEPKWFKGSLNDLFVARKAVEHVANRPAILRKDFIIDPYQIMEARLNGADSV FT LLIVAMLSREQLESLYKFSKSLGMEPLVEVNCAEEMKTAIELGAKVIGVNNRNLHSFEV FT DLSTTSKLAEMVPDDVILAALSGISSPADVAHYSSQGVSAVLVGESLMRASDPAAFARE FT LLNLSSSEISNGKKTSTPLVKVCGTRSLLAAKTIVESGGDLIGLIFVEKSKRKVDLSVA FT KEISHFVHTTNRKHISPKKAVTGQSWFDHQYENLASSPHPLLVGVFQNQPLEYIRSIIA FT EVNLDIVQLHGQEPFEWIHMLDRPVIKVFPLNSSEISRPNYHIVPLIDAYVGGESGGLG FT KKVDWEAASFIPVSYVLAGGLTPKNVQDAISVSRPAVVDVSSGVETDGKQDLEKIKAFI FT NAVKEL" FT misc_feature complement(14474..15130) FT /note="Pfam match to entry PF00697 PRAI, FT N-(5'phosphoribosyl)anthranilate (PRA) isomerase," FT misc_feature complement(15185..15970) FT /note="Pfam match to entry PF00218 IGPS, Indole-3-glycerol FT phosphate synthases," FT misc_feature complement(16091..16660) FT /note="Pfam match to entry PF00117 GATase, Glutamine FT amidotransferase class-I," FT CDS join(17724..17869,17992..18475) FT /db_xref="SPTREMBL:Q9Y7Z1" FT /label=SPBC1539.10 FT /note="SPBC1539.10, len:209, SIMILARITY:Saccharomyces FT cerevisiae, YEJ2_YEAST, hypothetical 26.9 kd protein in FT mnn1-pmi40 intergenic region., (231 aa), fasta scores: opt: FT 169, E():0.00089, (31.7% identity in 227 aa)" FT /gene="SPBC1539.10" FT /product="hypothetical protein" FT /protein_id="CAB51342.1" FT /translation="MANPRQRNKQRSGKPRLTRRNANKKAKAKIYGNFVIQQNWDKHAT FT LRQNYARLGLLATPNYVTGGVEKLYPDPKRENEDRELTSEELDELKKSLPPGQAIVRRD FT DDGNIIEIIHGEAKTLDDVLDKEISIAPAKTEVVRQLEEEAVKKAARQSNKMLPLSAFE FT HAYIQRLINKYGTEDFESMAKDVKLNSKLFNGSKLKNLYIRMKATK" FT misc_feature 17870..17875 FT /note="gtaagt, splice donor sequence" FT misc_feature 17977..17991 FT /note="ttaacaaataaatag, splice branch and acceptor" FT CDS complement(18878..19920) FT /codon_start=3 FT /db_xref="SPTREMBL:O94614" FT /label=SPBC1539.11c or SPBC1289.01c FT /note="SPBC1539.11c, len:346, FT SIMILARITY:Schizosaccharomyces pombe, YAIA_SCHPO, FT hypothetical 103.2 kd protein c24b11.10c in chromosome i., FT (932 aa), fasta scores: opt: 292, E():2.4e-10, (28.4% FT identity in 292 aa) also some similarity to, SKT5_YEAST, FT protoplast regeneration and killer toxin resistance FT protein, (696 aa), fasta scores: opt: 259, E(): 1.8e-08, FT (29.4% identity in 272 aa)" FT /partial FT /gene="SPBC1539.11c" FT /gene="SPBC1289.01c" FT /product="hypothetical protein" FT /protein_id="CAB51343.1" FT /translation="YETGAFDVESDIQRAWDLYSSSANLGYTRSLYRLGVLLEDQGNLE FT EAVEYFEKGVSENDSACCWRLSLLILEGMLDGVGEYAHRHASGLELLERSADTADADVP FT SGLYSHALVNLHEHPGLVDLGSENIRVPIDEATALKSFAKAAFLGHSSAQLRMGAVYEF FT GKYGCPVVPRYSLFYYSAAAKRGETEADLAVAKWYLNGSDGIPVDEDLAFMHAERASMA FT GNANAQFLMGYLFDTRGNTEQATYWYNEAAKAGHSEAIERLALLENQIQEPEPENITSS FT QYPNQDVIKEIPVTASETSPPHAPAVSSTPVTSAPPVSQTKVTKVSVPKKTSKKFLIKH FT NKCIIS" FT misc_feature 19798..19920 FT /note="nominal overlap with cosmid SPBC1289 S. pombe FT chromosome 2" XX SQ Sequence 19920 BP; 6413 A; 3613 C; 3485 G; 6409 T; 0 other; tgcgtgacgg tttggtttca aaacagtgtt tagcagatat gctgaaaaag ataagggagc 60 ttaaaaaacg tagtttgtga atggatgcca atgacttaca actcgatcaa taagattttg 120 ggatgcagct tatattatac aaatgttgat aaatatgaaa tatattatta actactgact 180 gaatgaaaga ggcgttaaat aaatcgatag taataataag cgtatggcaa aatgtactat 240 attatggcat cctttgcata aagaatttta tcctgctgct acacatctta ttgattatgc 300 acggtattag gtctcacgaa atcttttgtc aaatctgata tgatgctttt cttacaaaaa 360 ttcatagcct caactccgcc tttttggaag taaacgacag caacaagtcc ggaaacaata 420 ctactgtata tcttttcaaa actagacgaa gatggagaat taggcccttt taatggcaaa 480 atacattgtg tggcagtttc aggattccat ttttttgcaa cttcagcgag tcgagcaggg 540 gaacgaagat ttactaaatc cttgtatgaa ggtattgtgc taaagtttcc tgattccaaa 600 taatgattaa gtaagcaaac atcgataact gcatttccaa ccgaaacgaa aggttcatta 660 tatcttttca gcccatgttt ataagattta tgagttacaa tttgttctct tagagatttg 720 tctgagatgt aatttttttc accaaaaaca cgactgaaaa agctgtcaat gtcttcttct 780 gtagatgtca tttcatatct gtacttattt tcattacacg caattttccc aattcgacgg 840 acacaattcc atgatgatga tctgaacaca aatttatttt caatttgaag tcctaaacga 900 ttacaatgtc ttgttaacat acggatggca taaaatctta gaaagagctt caagttcctc 960 aaacccttgt atggaaaatc aacttttcga aagaaaagat atctgttttc tgcaactaga 1020 atataggttg tttttaaaaa acattggccg attacgaagt agtaaaatag cgcactacgc 1080 ttgagatcac agtgtacgaa cgtcaaggta tgctaatgtt atcaaactgt ttcaataatt 1140 tacaatttat tttgtgtttt actgttaagt gtatataaac aactactaca aagttattcc 1200 aaagaaacaa ttaattgaaa ggatactgaa gttttggttg aaaatttgtc acaatgaacc 1260 aagatgattt cagaaagctt ttagctactc caaaagccga aacctcccag ttaaaaaatt 1320 tctcatcgaa taaaagtcag cgacttgttt ttggtcgtaa acataagacg gccaaattgg 1380 aagcacccag agccctaatt aaaagaaaac aactaagtca ttctacatcg tcagacatta 1440 cgagacattc taatgcaaaa aattcaggga aagatactca attttatgaa gagccttctt 1500 ccaaacagga tattgagttg cacaaattgc acgagaaact tcgcaatggc caaattacga 1560 caaaagaata ttcagaaaaa tctaaagaat taggcggaga tttgaataca actcatctcg 1620 tgcgtggtct tgatcgaaaa ttgcttgaaa aagttcgctc taatgagcta gccttggatg 1680 attctctgct ttcttcgagt gagaaagaag ttgacgaaga agcagacaag cttttagaga 1740 aagttgctga ggagtcatca catcctgaat ctgtttctat tctagaagaa aaaaagaaga 1800 tacctcttta tcctaatgga caaccgaaat atcgtaaaat tttggaaaat ggaaaaaaag 1860 ttaaatattt gcttgatgaa aatggtgaaa tcctaaaacg gcttgtgaag aaggaaaaaa 1920 agttaaaaaa tgataatgaa cgtttagaaa atgaacatag aaccgagaaa ttaaacgtga 1980 acgctaatag cttagggaaa agctttgtta agcatgatat accacttcca ccagttgatt 2040 tgaagctcga tattttcgag gaggttggag aatatgatcc ttttcatgaa aatgataaag 2100 agcctgctga gttgaaggcg aaggatgctt ttcagcttaa aggtcatcat gaattggatg 2160 cgccttatca taagaaagtc tttgatacaa atcaatatag cgatcttaaa cctacgaatt 2220 ttatgtctca aattcatcga cttgccaaag ttcaggaacg caaagaagaa gaagagcgaa 2280 agaaaggaaa agacggacaa attgttgatg caggtttcgg gcttgtatta tcaaaagacg 2340 atacagcaga tattcacgag ttaggggaat ctgacgatga tgataatgtt aaaaggagaa 2400 agacgaaagg ttaaaagtac tacttcattc agtatgaata tttacgattt aagatttaag 2460 ttacgtgttt ttaaaatatt attatgaggc tacaattatt tatttgcccg ttttacacca 2520 aaaaacctcg attcggggaa ttatgttgag gaagccctgt taaatgatca aacgaacata 2580 tagaaaaagt aagtatatcc atatcatttc atgtaaactt atctactcca aggccttttt 2640 aatggtttgg atttgttcta atacacaact cttagcggta ccaccaatcg cacaacgctt 2700 ctccacactg gattcatagt tgaaaacatc tgcaacatct tcttcatata atgggtgtag 2760 cgatttaaaa tcttcaacac ttagcttatc aatggtagtg tttctttcct cggccattcg 2820 gacagcggac ccggaaatat gatgagtttc acgaaaggga acacctttac gcacaaggta 2880 ttctgccaaa tcagtcgcta gcatgtccgc agtcaagctc ttagcaatat tttctggatt 2940 tacagttaaa gtagaaagaa ctccggttag aatttgaatg gaatccaaaa cagttttgga 3000 agaatcgaaa agcggttctt tatcttcttg gaggtctttg ttatatgttg aaggaatccc 3060 tttaaccgaa accataaagc ccatcatgtt gccaaaaact cggccagact ttccacgaag 3120 aagttctaaa gaatcgggat tttttttttg aggcataata ctacttccag ttgaataagc 3180 atcggaaagg gtaacgaagt tgaactcaga agtagaatat ataataagat cctctgccaa 3240 acgggaaata tgggtcatta ccatactagc ccagaacata aattcaataa cataatcgcg 3300 gtcagctaca gcattcattg aattcataat aaccccttca aaaccaagtt ccttttgtaa 3360 gaacttacga tctacggcga aaggattacc agcaagtgca ccagcgccta aagggagtcg 3420 gttgactcta gaataaattt gtttcaagcg atccaagtca tttaatatag aaaaggcatg 3480 agacaataag aaatgggacc agcgaatagg ctgggctctt tgcaaatgag tgtaaccggg 3540 cataatgata tcaaggtcag actctgcacg agcaacaaaa acttggagta acccaactaa 3600 agatttttgg atgatgtcca actcatcacg tagccaaagg cgcatatcgg tcgtaacttg 3660 atcgttgcga cttcttcctg tatgaagctt accagcaatg cctgtaccaa ttatttctcc 3720 caatctgcgc tcgttagcag tatggatatc ttcgtcagaa ggttgaagag tgaatttatt 3780 tgtcttccat tcatctcgga cagcctctaa accatctaac attttatcca attcatcagc 3840 actaatgatt ccgcgttgtt ctaatgcctt agcataagct ttcgagccat caatgtcggc 3900 attgaacatg cgcttgtcat aatgaataga ctcattataa gctgtcatca agggatcagt 3960 ggcgccagta aatctaccgc cccaaagttt ttgtgaagaa gccattcaga attgttaaaa 4020 cagagtcagt ttttcaagtt ttcaaccaac gcaaaaagga ggtagtacta cttaaaattt 4080 aatttatcta atcttttgag agtatggcta tatgaccgtg taacctcttc cttatcgcaa 4140 cctattgtta tatcacatta acgatacggc gatagatatg aaattgatat tataatcgct 4200 ataataagat ctaacgtatt ggaacgtata aacacttaat aaatgtttac attccgcttc 4260 gttatttctt tccttaagtt tacaaaagat atcatatatg gaagctttgg ttggaatctt 4320 actgtataaa tgtactcaac ctgaatgatt tgttttgtct ttctgattta ttaactcaga 4380 gctaccaaag aatttcgcga gcattagctt agatttaaga aaattgactg ttataaagat 4440 tgagaattct taaaagattt tcttgttagt tgtgattgtt ttttcgattt ttattagaac 4500 gatatttata gatgcctgaa aactcattgg tagataagta ttgttttctc gtttttacta 4560 gtgtctgatc agactaaact ggtttaaaca ttatgatgca tcttccgccc aatttctttt 4620 aagatagcta acgaaaatca attaaaataa acatggacca accgagttta tgaatccacc 4680 aaatatagtg ggattataaa gaagaagaaa atcaacgaag aataaagtga taacagtaca 4740 tgattttcct tttccctctt tactttcgtc tcttactgcc ttaaattata cactgcattt 4800 caaattgtca actatattat tgatttcttt tggcatgaac acatataggg cgtattactt 4860 cgacagtcta acatttactt ataccaagct tctcaaaatt cgtttatagt actcgtcttc 4920 gccaacaaat aacttaacaa tttacgtatg gatatgttgt taacagaacg tctggactca 4980 aaacggaatc cacaaagtgt tatcttcgag aatactctag agccagttta gatcttgcta 5040 gttattttta aatagaagtt attgaaggtt gccgagcaat acaagtgtga tatagtaatg 5100 ttgaatctga accatttatt gtccactagt aaatgtgcaa gaattaatcc atttattgtt 5160 tccatgtaaa acatagaaca gatagcgtaa caaacaacat cgtactttag catttcactt 5220 tgaaaaattt tagtcagagc ttcttgtaca ttgttatcaa gggtcgtaaa tgaattatgt 5280 tagctttctg gagtgtctgc tagacttaaa caattggatt ttagaaaact aaagagtgta 5340 gcccctattt aaatctattt aattgtaata gcttgaatgc tactcaaagg cgtaaatcct 5400 tttttaagcg cttatattcc tgctaaaaga attctagtca aaacgtgtac tagcgtattt 5460 cacagaagtt ccataggttt tctttttctg atgtaggaaa atttaggatc ttccattggt 5520 aagcgtacat tgtactctat cacaactatt acaacatact ttttgctgga tattaactta 5580 acaaaagcca catctttaaa actttgaaaa taacaacttt gctataatgg agccaaaaca 5640 acgagttgtc aagcctttaa aagaaagggt tttacctgtt gtcaaggtaa atatatctat 5700 catgtgtaaa tcagataata aatgttgatt ataagaaaag tttcttattt agttccataa 5760 cgtaactgta atctattact aaaacataga ctaatttgtc agcattattt tattttgatt 5820 cagtgtcata ttgtcttcac tcttttaata cattactaac cgtttattat agaacaccca 5880 gtttgtttgg ttttcggggc aagtaatagt gctaatctct tccgtcttgt atgctcttca 5940 agcaatccct tttcgttccg ctcctccatt tttgtttaaa agcgctgcct ttggtgccat 6000 cgttgcatat gcaattgtcc tttacaaaac ttatagtcca aacttgactt cccgtgcttc 6060 ttggaataag catttctttg cccgtcttat gctcgatgac aatgttcagt attttatttt 6120 agctctttca atgttgattg atcgtcccat cctattttct ctcgctccat atgccattta 6180 cgccactttc cacatctcca cttacttgcg tagtgtgctt ttgcctgcca tttaccctaa 6240 tatttctgac gcgaaaactg cgtcttatgc ttctcgtgtt tctaatttgc taaatcagta 6300 cactcgaagc caatttcaac ctgctatgca acttgttgct tctctcgaaa catttttatt 6360 gttccgtttg ttctttgggg ttttcttacg taaaaactca atttccaggt tggtgggcta 6420 tattttcttt cttcgcatga gatacactaa tagtcacttt actcgtgcat ccattaaagc 6480 cgttagcctt cgaatggatc gtttggttgc agataacaga gttcctcctg ttatcaaaaa 6540 tgcttggcat acattcaaaa cttatgtgtc caagttcggt gcttcacctg taggtactgc 6600 tcaaagccgt cccactgcat caagctctac cactgctccc tcatctactt aaagtgatgc 6660 cttattcctt ttgattgcta gagatttata taaatttcac caatcagtgt gattttaata 6720 tgtctaagtg ctcctggttt ttgagttctt tactattaac gagtagtttc tatttcaccc 6780 aagtaaattt tgaatgttca taccgtttac ctctttctct aaaaacttgt ttgagataat 6840 tccgtttatt tatttttgct cactactcct ctatttcagt tatctttgtt tggggggtct 6900 cctcagactt tagtttagct tttttcaagg aaattgaaat atggatatat gttgtttatc 6960 caaaaactct ttgagtatta aaagattaag aggtaaaaat aatacgtttt attgaatttt 7020 gtagcacaat aaacacatgt atagcagcgc actcttgaaa tctagcaagt tattagttta 7080 cattggataa aataccagtt tcaattgaat ttatgtgatg ttaatgcgtt ttgtttctta 7140 gcatctgcgc aaagtaacgt agcgctgtgt tatggttcac tgggaaacac caacaaagtg 7200 ctcgatgttt ttctgattat cgtaattatt ttgaacgatg tttgatcagt tggagtttta 7260 tcctgctgtc aactatgagg ataatgaaac tcaaaatgat ataaaagtaa gcttagataa 7320 atgtttttac aagggcttac ccaattagct acccgaagtc gccaaacttg aaaatatcga 7380 aacagtgcat tccatttcta aggaaagacg cgactcttta acggaaattt taaatgattc 7440 ttcaagctta ccggcacgtc cgttttctct gcctaatccc aataattcaa ccgtagaaaa 7500 gcagtcgtta tttccatttg aagaaaagat gaaccccata tggataattt ctagacctac 7560 tttctctatt gagcaagacg cggaaaaaaa aattaatgaa cttcaaacgt ttacaaacat 7620 tattgatcag atattgggtc agactaataa cattgagtca acattgttat caatgaaaga 7680 aaagtttgaa agttctgaaa aaaagctgag tgaattctct gaaatgtgtg agaaccttag 7740 tacagatgag gtattaggag cgtgctgcat accacttatc attactaaca ccttgaacag 7800 atgcggtttt ccgaaatagc cgatggcata agaaaaggat taacaatttt tgctcctttg 7860 aaagagctta ctcgagtttt tcggcatcca cctcctgact ttgctggcaa agtttccttt 7920 aaagagcaca ttactcaatt aaatacttgc atcatgttcc ttgaagaaaa tgtacgaaat 7980 tccatgtttt ttattttagc tgacttttta gttggatttt caagaaagtc cgcattacct 8040 tggtcaatac aagaaactgc tatctcaagc gatggatata tttaaaccgt attttatacg 8100 gataattaaa caaactactg atcaagtgct aaaggattcc aaaaaaatgg taggcatata 8160 cttttgggcg tttttgtttt ccccaatcat taacaactat ttaggatgtt cacaaacagc 8220 ttcatagttc actcttctac gcccgattta gtgctgtagg tcataacctt tgccccacta 8280 tcactgaatt atgtaaatta tgctctaaag aaagtttaga tgcttttctt cctgcttttt 8340 atgatgtcta ttttcaatgc cgcacgcggc ttctgaaacc tgtactggat tatcatttga 8400 aaagtttttt tatggagaaa tccatttcaa gctatgtatg tttaacgaaa catatataat 8460 taactaatga taccgtagat ccaaaaatca cttgctcttt tacaacttac tttttttgat 8520 gaaaataagt tattccgtga aattcttatc atggatgatt ttcgatttat gcattattgg 8580 aataatcttt gtcaaagctt ttttgaaaat agtcgttcat taattttgca tgaaaaaaac 8640 cttaccgaac tttgcgaggt gtgttcttat atccaatcat ttcaaaacgc cattttagaa 8700 ggggaaaggg aggacgttga taaaaaggtc gttgaatttc ttaatcctct tgtacttgag 8760 ttgcaagagc gtcttttatt tgtggtacaa actgccattg aaaccgatat tcaacgatat 8820 tcccctacgg aagaagattt aaatcctatt gcagatgaca aaagtttgct cttcgactta 8880 gaaaagttac gcttgaataa tgatgaagaa aagctagacc ccgatgttcc acaaaaactt 8940 gctatggctc aaggctggta tccggtagta caaaaatctt taattatttt gtcgaaaatc 9000 tatcgattgg tgaatgtacg tgtttcattt agactttatc cattaacagt ttttagtctc 9060 aagtatttga cgagatagcc cttgaactcg tgcactcctg cattcgttcc ttggtagatg 9120 cgtaccgcta ttttagccgg aacaatgata agcagttagc aaggcttttt ctaatcaaaa 9180 attttttggt tttaaaagac cagttgaact cattcgatat acattatgct tgtattgaag 9240 ctggcgttga tctgcgaaaa gtatgggata gtgttcgtga atggcgttct aacttgagag 9300 gcgtcttaca acttgtttac gaaacgtttc ctaaatttat tacaaatgcc gtagatacca 9360 ggcaggaact taaccagcag ttacgtgtag cagtaaatgg gtatatcgaa actgcagtta 9420 tacattacac ggaatgctta agtatcggaa acctcgaaag cataaccgag tttcaaaatc 9480 gaattcaaaa gtttcctgag ttgagacagc aaatctcact ctacctttca gaaacgtgga 9540 tcatcgaact gtttttgcag gctattcgag aagaagttgt cagtaaattt caaaattttt 9600 acgaatcaat agttgcaaat gaagatatta caggaagtga ccacaataag agtggaacaa 9660 cttcgttaaa gcatttaaat gaatacgttg aagatattta ctccgttatg agttgaatat 9720 ttaatacgtt gatgacccga ctagattttg aaaacatatt tcatacttat tttttgcata 9780 gtttaatcaa gttgaagaaa tttaccgttt taaaaatcgt ttcaaaatta taaatgtatt 9840 tctatttgac attttgtatg ctgtgcattt aatttttttt tttatttata aaccactggt 9900 aagtatcggt atataaaaac aatttctttt cttcttcgta aatatagtga aaattcaatt 9960 ggggattata tagtattgtc gatattagac cgagcaactt cttgtcatat ttaacaaatg 10020 taaatatatt atattatgat atgcaaaacc tgagtattgc aaagtctgtg ggttcgaact 10080 ctgtaggtcg gataatatat atgtatatat ataatggatg tcaataatca cacggtcttt 10140 aacctgcaac aaccatgtct tctactttcg agcaagctgc cgctgacgtt aaagaattaa 10200 aggaaactcc taacagtgat gaattattaa aggtattttt ttcttaaccc cctttttttg 10260 tagcttagct tactaatttg ttgtactagc tttacgcatt atttaagcaa gccactgttg 10320 gtgataacaa cactgaaaag ccaggtctct tagatcttaa ggggaaattc aaatggaatg 10380 cttgggaaga acttaaggga aaatcgaaag aagacgctgc ttctgagtat atctctttcg 10440 ttgatgagct taagaccaag tatggaatga agtaacgctt ttgcctgtga acagtagttc 10500 tttcgatgat tattagacct tacactcgta aattcttgga attacgacaa acgattaatt 10560 actgtatgtg aagcatttgt tagtttacaa atgttcagcc ctatttaatc aaagatacca 10620 atgatcatat tgtttatacc tctaatgttt atcattcatt cctttatcat ttcgaaaata 10680 tgccaagtag acagaaaaat tccagtgtga atgagataga aagaatcatg tatgcttact 10740 cttacatatc taaaaatgtg agtatcctat tgtaagctgt agcatccaaa tcttttttaa 10800 accataaaac tagtataaca attcaacatg ggttattcac atagcttacg caaagatgtc 10860 aaagactcgc atagggtaca atcgtgaagt tcgaaattta cataaaagtt ctttatggct 10920 tattcatatc cacgacgcat cttatgcact ttccttcgtg catatggtcg aaagctttgt 10980 ttatgttctt aagtggttct tcattagtga tatattcatc cactttgaag tggccttgca 11040 tgtactcatc aacaaagttc ggcaattcag aacgcccttt aactcctcca aaagctgaac 11100 ccaacacttg acgaccagtt actacaagga atggacgaaa atcaagggtt ttaccagctg 11160 cggcgacgcc tataacacac agtttacccc aacctttgtg gcagaattga agttcctgct 11220 gcatgacagt gacatttcca gtgcaatcaa atgcatagtc aacaccacca tcagtcacat 11280 caataacata ctgtacgagg tctttaactt tagaagaatc gataaagtca gtagcaccaa 11340 atttcttggc atatacttcc ttatctgcat tgatatcaat agcaatgatt ctcgaagcac 11400 cagctgcaac cgcaccctgc attgcagcga gacctacgca tccacatcca acaacagcta 11460 ccgttgaacc agactcaacc ttagcagagt gtgtcacagc accaaatcca gttgtgacac 11520 cgcagcccaa caagcaaata ctgcgaagag gtgcggagtg tgaaatagcc acaagcgaga 11580 tatcagctac aactgtgtat tgactaaagc tagaacatcc catgtaatga agcaacgttt 11640 tatcgcgaca ggaaaagcga ctagtaccgt caggcattaa acctcgacct tgtgtttcac 11700 gaattttgga gcacaaatta gttttaccac tacgacagaa tttacactct ttacattccg 11760 gagtatatag caaaataaca tggtctccag gacgcacgtt gataacccct tcgccaatgc 11820 tttccacaat accagcaccc tcatgaccaa gaacaatagg gaatgcgcct tctggatcta 11880 caccagacag cgtgtaagca tctgtgtgac aaacagcact ccaatcgact ttcacacgaa 11940 cctcatgagc ttttggaggg gcaacctgaa tactgtagta tcacctccca ttctgcccgt 12000 tgatgagcag aagagaagtc aaaagttagt aataaaattc aagtataaat tcttttcctt 12060 ttgtcatcat tatacttact cctctataga taaaggttcc tttgcacccc aagctacggc 12120 tgcctaaaac gaatgttatt agtacacaga aagaaaaaat aaaagataat tatccatata 12180 ctcatggatg aacaataata tcaaaagtaa acctttggtg gacttacagc accaatatca 12240 tttacacttt agacaatgat ttacgttttc tttttcatac cttgcaagtg atcgttttac 12300 cttcgaaaga catgtttcat taaagactat ctcagaatgt gtatttggta gaaagactgt 12360 tacagtttta acatttaggt ctacttactt attacatatg cttactacta gataggtcgc 12420 gactcggatg aaaattgtcg atcatcgtcg atcttgtatc tcaatagtca cttgctagat 12480 agagagatat acatacaaaa ataaagaatc aatattaaaa agtacaattt aaaatacagt 12540 gctagcatag aaacatatgt tacgaaaaca ttagtttgtt tataattcaa tacttgaagc 12600 cttcttctac taaatgttat tttatatgat tgttttttat ttttattttt ttttgaaaaa 12660 tactttaaat aatgaggctt caaatcatta acatacactg ttaaagttga gtaatataaa 12720 tctgcgttat taggcaaggg aatgagaatg tttctattca ataaacttga tggaaattcc 12780 aaaagttaat cgataaaaat aatattctta atatttaatt tattattcgt acatgggatt 12840 tacgatatag tacaagacca tgggcttcca tataattcag ttacgcagct cgttaattta 12900 cattatgtat cagctcggct taattaaata tttcagacag agagagttga tatcagctgc 12960 acctacgttt agtgctagcc gtcttttaaa gtacgaagaa agccctgtat ctgggttcaa 13020 tataaattct acttctttgg tttttttggt ctattctttc ttttggttat cttcttctgg 13080 gattatttga taccatgggc aattcactat ttaaggggtt ttcaaagcca tttagtcggt 13140 tgttttctaa caaggaaatg cgtatcttaa tgctaggtct ggatgcagct ggaaaaacga 13200 gtatgttttt tattcggatg gatttttaca gtcttcattc cgtataatcg tgcttaactt 13260 ggtgttttaa taatggtaac tcttttatta acattttagc tatcttatac aaattaaaac 13320 tcaatcaaag gtaaagagca ctaaacagca ttcttcgatt gtgtcaaggt atcgtatgcg 13380 ctgcttctgt attagcatag tagatataga tttcattacg aagactgttg gttaattaat 13440 cagtgaagtc tactgtcgcg cattatcttg agttgcaatt atgcttccgt aaatgaaatt 13500 gatttttctt gtgttcatta actaacagcc agtgttgtca ccattcccac tgtgggtttt 13560 aacgtcgaaa cagtcactta caaaaacatc aagtttaacg tttgggtata tttataatca 13620 atcttgggtc gagcatgttc taacgttgat ttgtttgtag gatgttggag gtcaagataa 13680 aatacgacct ttatggcggc attattttac tggaaccaaa ggattaattt ttgttgttga 13740 ctctgccgac agcaatcgta tatcagaagc tcgtcaagaa ttgcatcgca ttatttcaga 13800 tcgtgaaatg cgggactgtc ttcttttggt gttggctaat aaacaggatt tgcctggagg 13860 taaggttgcg aatccgaata acttatgcta acactatggt agctctttca cctgctcaaa 13920 ttaccgatgt tttgcagcta gacaaattga aggatcgttt atggaacgtt cagccaacat 13980 gtgctcttac aggagacggg ctgttggagg gtctggcttg gctaagtcaa aacgcaaagt 14040 taaaataatt tgcttctttg atttgttaat acatggtgtt tatttcgttc gttatcccaa 14100 gaattgcaaa taattacatc gatcagcttc cgttctatcc ctttatcgtt gcttaattaa 14160 atctgtacag tctttactat tcattttctt tctttagcat ataactttac tattgccaat 14220 cgtttcccta ttcctactat cactttataa tgtgcttcat tcggccaaat acatttggat 14280 aacagccatt tttgtcaata aaatatttct taatttaata cagaaaagtg atcaataacc 14340 agataatata attatcgcac acttcttatc caacaaaatc taaaaccagt tattttaagc 14400 gaagtctcat gatatgtatc caaaaacatc tagacaaact tgatttaatg tagacaagtt 14460 aaagttcttt tacggcgttt ataaatgcct tgatcttttc aagatcttgt ttcccgtcag 14520 tctccacccc actcgataca tcgactacag ctgggcggct aacagatata gcatcttgta 14580 catttttagg tgttagacca ccagctaaga cataagatac tggaatgaaa gatgcagctt 14640 cccagtctac tttcttgcct aaacctcctg actctccacc gacatatgca tcaatcaaag 14700 gtacaatatg atagttgggc cttgaaattt cagaagaatt tagcggaaac accttaataa 14760 caggtctatc gagcatatgt atccattcga aaggttcttg tccatgaagc tggacaatat 14820 ccaagttcac ttctgctatt atagaacgaa tgtattctaa tggttgattt tggaacacac 14880 cgactaacaa agggtgcgga gaggaagcaa gattttcata ctgatgatca aaccaacttt 14940 gaccagtcac tgctttcttt ggggaaatgt gttttctatt ggttgtatga acaaaatgtg 15000 aaatttcctt ggccacggac aagtccactt ttcgtttgct cttttccaca aaaattaacc 15060 ctatcaaatc gcctcctgat tctacaatgg ttttagcagc taacaatgaa cgagtaccac 15120 ataccttcac taggggtgtt gatgtttttt taccattaga tatctcgcta gaagaaagat 15180 taagtaactc tcgtgcaaaa gcggcaggat ccgaagctct cataagagat tcaccaacaa 15240 gaactgctga tacaccttga ctactataat gggcaacatc agcaggacta ctaattccac 15300 tgagagctgc aagaataaca tcatctggga ccatttcggc taattttgat gtagtggaaa 15360 ggtctacttc aaaactatgc aaattcctgt tattaacgcc gataacttta gcaccaagtt 15420 ctatagcagt cttcatttcc tcagcacagt taacctctac taacggttcc atgcccaaag 15480 atttagaaaa tttatagagg gactctaatt gttcacggct taacatcgca acgattagca 15540 atacactatc agcaccattc aaacgagcct ccataatttg ataagggtca ataatgaaat 15600 cctttctcaa aattgcaggc cgattagcta catgctcaac agcttttcgc gcaacaaaca 15660 aatcattcaa tgagcctttg aaccattttg gttctgttaa cacagatatg actgaggcgc 15720 caacctgagc ataagtaaga gcttggatag cagcatttgc gtctaactta atgtcacctt 15780 tagaagggga agcacgtttg acttcagcca ttaaagctgg tttagattgc tttaatctct 15840 cataaaaatt tatacatgga ggtgctatgt taaggttcaa atatgtttgc aaatcaccca 15900 cagaaagacc aggctttctt ttactttcag caatgtcaat aagtctctgc gcgtggattt 15960 tctcaaggat agattcttgt ttgcgaattt tagttgaaga aacagaattc gaattttcac 16020 gcatagccgc gttaaatgcg ttattttttg taggcataac aatgccattt tcttcccagg 16080 ttccagcagt gagattcaaa aaattctgaa tatactcttt gccatactca ctaaggatac 16140 tttcaggatg gtattgaaca ccctcaatag catacttttt atggcgtgca cccattatta 16200 caccattctc ggtccagctt gtaacgtcca aacaatcagg aagtgatgaa atttttccag 16260 caagagaatg atatcttgtt acagaaatat tttgaggtat tccttggtaa aatccgagac 16320 cgtcgtgatt tattttagaa acttttccat gtatgatttc accagcggaa tcaactttac 16380 cacccattgt ctcaaaaata cactgaagtc ccatacacac accaagtata ggaatctttc 16440 cagcaaatct cgaaatagcc tcgttacaaa taccaccatc acgcgcagga tgtccaggcc 16500 caggtgagag aactagtttt aaaggattaa gtttttctaa ttcatcgaca gtgatttcat 16560 cattgcgaaa aaccataata ggatatcgtt tttccagatt agaaagatat tgaacaacgt 16620 tccaggtgaa actgtcataa ttatctatca taacaattgg tctttcagca acttctttaa 16680 ctgcattttc tgaggcgtct cctttgacgc tttcaccaac gtcaactttt tcagacattt 16740 tcagcttgtt ataattgaga cgtgctaacg ttaattttcc aaaaactcaa aaccaaaaat 16800 gctgaatgaa aaagtagccg atgatggcaa atgacaattt cgacttttga atgatcggga 16860 aagatagtat agaagcgatg tttcttgcta atgtattttg cgaactgcaa cgaaaaatat 16920 atttggtttt aagacattgc aactaagaaa tcatcgcata atgaacgtta gcaaataacg 16980 ataacaatcg ttgtactatt gtactagaat tagcaggtaa agaagaagtt tgacgaggag 17040 aaaacgaaat tttttttata ctggggttag ggaataacga aatcataaaa ataatcttta 17100 attaggcata aaaaaataat taaaaaattg gtgtttcaat tgtcggttca tttaaaactg 17160 ttaatataat aaagttgtaa accaaatgac taaacagtga ttttaaaagt atcctatagc 17220 tgttgtttac tctggtaatt cgacacgtaa aatacatgat ttctcgactt caacaattct 17280 tgggaatttt tagaaattta cagttagtgc tagatattgg aatgccacta aaattagtgt 17340 attcgttgag gaagatcaat ttataaattt tgtttcaaga ttttattgaa atctctatga 17400 gaatattata tcgtttcaca attcatacag ctttataatg tagacaaaaa aaagatgagg 17460 gtacttaaat tttatacaat accaaaagga ttgatgataa atgtgataac tgtcaacgtc 17520 tattaatttg agaaatataa attaaatgga caacagtcat tgttaaacta ggtcacagaa 17580 ctatcttatt gtgtttcgtt gaaatattat gtagacatac tgcacgtagt ctacattcac 17640 ctccacttaa actcacgaac aaccaaattt ttttgattgc ttaccaattt ccatttcccc 17700 ccatttatct ctaaatagat aagatggcaa accctagaca aaggaataag caaagatctg 17760 gaaagcctcg tttaaccagg cgtaatgcta acaaaaaggc gaaggccaaa atttacggaa 17820 attttgtgat tcaacaaaat tgggataaac atgcaacctt aaggcagaag taagttaata 17880 agtattgctt tatttgtttt atacaaatga aaattgagga aaaagttttg cgctccttct 17940 tggtcttatg ttcttttctt tcttatagaa ttgctattaa caaataaata gttatgcgag 18000 gttgggtctt ttagctactc ctaattatgt tacgggaggt gttgagaagc tttatcctga 18060 tcctaaacgt gaaaatgagg atcgtgagct tacctcagag gaattggatg aattgaaaaa 18120 atctttacca cctggtcaag caattgttag aagagatgat gacggaaata ttattgagat 18180 tattcacgga gaggcaaaaa cacttgatga tgttttagac aaagaaatta gcattgcacc 18240 ggctaaaacg gaggttgttc gtcaactaga agaagaagct gtaaaaaaag cagctcgaca 18300 gtctaacaaa atgcttcctt taagtgcatt tgaacatgca tatattcaaa gacttataaa 18360 taagtacgga actgaagatt ttgaaagtat ggccaaagac gttaaattaa attctaaatt 18420 atttaacgga tctaagctca aaaatttgta tattcgcatg aaggctacaa agtaaacatc 18480 aatggtgata tacggacggt aaaatggtga ttgtgttcta ggtatattta aattaataaa 18540 tttttatttc aatactatta attctattag aaagcaaata ttgagacgac taatttgtat 18600 gaaacaataa ttacacagta tgtatttctt cgtgatccaa ttttgtatta tactatcgaa 18660 aaagtagtga atgaaaacat gtatttaaaa gaaattgctt aaatggatat cagctaacta 18720 tacaattata aatgagcgtt agacaattcg aggacaaatg agagaaataa aaaccggatt 18780 atgctatgtg aatgcaattg aacactaaaa cgaaatttcg gggagaaatc gattccaatg 18840 ataaaaatga tgttctaagg gagcaaaaat tgccaactta agatataata cacttgttat 18900 gttttataag aaacttttta gatgtctttt tgggaaccga aacctttgta acttttgttt 18960 gcgaaacagg gggcgcagaa gtaacagggg tagatgagac agctggtgcg tgcggtggag 19020 aagtttcaga ggctgtaaca ggtatttctt ttataacgtc ttgatttggg tattgtgatg 19080 aagttatgtt ttctggttcg ggctcctgaa tctgattctc tagaagtgcc aaccgctcaa 19140 ttgcttcact atgtcctgct ttagcagcct cattatacca gtatgttgcc tgttctgtat 19200 tacctcttgt atcgaataaa taacccatca ggaattgagc attagcatta ccagccatag 19260 aggctctttc agcatgcata aaggctaaat cctcatcaac gggtatacca tccgagccgt 19320 tcaggtacca ttttgcaacc gcgagatcag cttctgtttc ccccctttta gcggcagcac 19380 tgtaatagaa caaagaatat cgaggaacga cagggcagcc gtattttccg aactcataga 19440 cagctcccat tcgtaattga gccgatgaat gacccaaaaa agcagctttc gcaaaacttt 19500 taagtgcagt tgcttcatct atgggaactc taatattttc agaccctaaa tctactaatc 19560 caggatgttc atgaagattc accaaagcat gactatacag tccggatgga acatcggcat 19620 cagctgtatc tgcgcttcgt tcgagaagtt ctagtccact agcgtgcctg tgtgcatatt 19680 ctccaacacc gtccaacatc ccttccaaaa ttaaaagcga tagtctccaa cagcatgcac 19740 tgtcattctc tgaaacaccc ttttcaaaat attcgacggc ttcttctagg ttaccttgat 19800 cttccaataa cactcctaat ctgtacaagc ttcgtgtata gcctagatta gcagaagaag 19860 agtataagtc ccaggcccgc tggatatcag actctacatc aaaggcacct gtctcgtaga 19920 //