ID SPBC1347 standard; DNA; FUN; 25930 BP. XX AC AL035548; XX SV AL035548.1 XX DT 24-FEB-1999 (Rel. 59, Created) DT 24-OCT-2002 (Rel. 73, Last updated, Version 4) XX DE S.pombe chromosome II cosmid c1347. XX KW actin like protein; casein kinase i homolog; cdc23; centractin; cki1; dnaj; KW fkbp39; meu14; oligoribonuclease; Peptidyl Prolyl cis-trans isomerase; KW protein kinase; ribose methyltransferase. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-25930 RA Wood V., Rajandream M.A., Barrell B.G., Rieger M; RT ; RL Submitted (24-FEB-1999) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and Biotechnologische und molekularbiologische RL Forschung, Angelhofweg 39, D-69259 Wilhelmsfeld, Germany XX DR GOA; O42709; O42709. DR GOA; O74191; O74191. DR GOA; O94623; O94623. DR GOA; O94625; O94625. DR GOA; O94626; O94626. DR GOA; O94628; O94628. DR GOA; O94630; O94630. DR GOA; O94631; O94631. DR GOA; P40233; P40233. DR SPTREMBL; O94623; O94623. DR SPTREMBL; O94624; O94624. DR SPTREMBL; O94627; O94627. DR SPTREMBL; O94628; O94628. DR SPTREMBL; O94629; O94629. DR SPTREMBL; O94630; O94630. DR SPTREMBL; O94631; O94631. DR SPTREMBL; O94756; O94756. DR SWISS-PROT; O42709; CC23_SCHPO. DR SWISS-PROT; O74191; FKB4_SCHPO. DR SWISS-PROT; O94625; SPJ1_SCHPO. DR SWISS-PROT; O94626; ORN_SCHPO. DR SWISS-PROT; P40233; CKI1_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c1347 it is overlapped at the 5' by cosmid 215, CC EMBL entry SPBC215 accession number AL033534 CC and at the 3' end by cosmid 56F2, EMBL entry SPBC56F2 CC accession number AL023288. XX FH Key Location/Qualifiers FH FT source 1..25930 FT /chromosome="II" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c1347" FT /map="IIL" FT misc_feature 1..29 FT /note="SPBC215.15, see c215 for full length CDS" FT misc_feature 1..995 FT /note="nominal overlap with cosmid SPBC215, EM:AL033534 S. FT pombe chromosome 2" FT CDS complement(378..3185) FT /db_xref="GOA:O94623" FT /db_xref="SPTREMBL:O94623" FT /gene="SPBC1347.01c" FT /gene="SPBC215.16c" FT /product="putative deoxycytidyl transferase; possibly FT involved in mutagenic translesion DNA synthesis; similar FT to S. cerevisiae REV1; putative damage inducible protein; FT PF00817 IMS, impB/mucB/samB family domain; BRCT domain" FT /protein_id="CAB37432.1" FT /translation="MAFNQRKRRRPVGIADFDEANDEAYESVGFHDYADYFSRKQRKLQ FT NQNAALYKSIDEDSKSDLFHGLAIAINGYTKPSYTELRQMIVSNGGTFIQYVDGKTSIS FT YLVCSFLTPSKARQWKHQKVVKPEWIVDCIKQKKILPWINYRTFQASSAQATLSFVASK FT PSQPEGNLEDIQTSSQEEEHDNEKDKTKESKAKGFLDDLSGLSASSLHNYQLLKNPNVR FT NSTTQNQDFLENFFSSSRLHHLSTWKADFKNEIQAMTTASEPVRPIMKDKSKKSRFLLH FT VDFDCFFASVSTRFSHELRLKPVAVAHGIKNSEIASCNYEARKFGIKNGMYVGTAKNLC FT PSLRVVDYDFGAYESVSREFYTILVNTLHDYIKVISIDEALLDITSSVSSFQDCFEIAE FT SIRSQVREKTNCEVSVGIGPNVLLARLALRKAKPHNVYSLSIENVFDVLSPLSVQDLPG FT VGSSQAQKLFNLYGVRTIGQLQRIEKFNLQETFGVNYGLHLYNISRGIDTDIINNETPR FT RSISVDVNWGVRFVFQEDGIDFLKRLLHELLSRMGKCQVLLHQIQLRILKRADGAPFSP FT PKYLGAGEVTSFTKSSTFTSATNSFDLIWKKVTSMYKTINVDPGDVRGIGLQALKIIKD FT NSKIRKDYRSIQSITSRNKVSLKGASVDISSKDKEIISQKKQLSPKLIPSTPYDLPSSS FT QISSSALAQLPPSMQSDIQQQLRLQKRSITEYPSQLDPLFMVELPTPIRNEVNDNHEIA FT MNKRLSLKSHADNKIDERGKKKIRQENAFDKLLQISKKSKTINKPNVDYLTLKELPKDL FT QKQILKESNLQKSDLISEVKLEKPHIVTFQHVQSLEDLRGLLTKWYSKASKGPNIHDVN FT YFANYVCRVIREEKNLGKAQMMLKWLYQLNRKECNKPWEKAIDKIIETVQGECLQRNIP FT PLMIF" FT misc_feature complement(1284..2342) FT /note="Pfam match to entry PF00817 IMS, impB/mucB/samB FT family" FT misc_feature complement(2745..3011) FT /note="Pfam match to entry PF00533 BRCT, BRCA1 C Terminus FT (BRCT) domain" FT CDS 3584..4669 FT /db_xref="GOA:O74191" FT /db_xref="SWISS-PROT:O74191" FT /gene="fkbp39" FT /gene="SPBC1347.02" FT /EC_number="5.2.1.8" FT /product="peptidyl prolyl cis-trans isomerase (FKBP-type) FT (EMBL:AF017990); similar to S. pombe SPAC27F1.06C FT (paralog); similar to S. cerevisae FPR3 and FPR4" FT /protein_id="CAB37433.1" FT /translation="MSLPIAVYSLSVKGKDVPAVEESTDASIHLTMASIDAGEKSNKPT FT TLLVKVRPRIPVEDEDDEELDEQMQELLEESQREFVLCTLKPGSLYQQPLNLTITPGDE FT VFFSASGDATIHLSGNFLVDEEDEEEEESDEDYDLSPTEEDLVETVSGDEESEEESESE FT DNSASEEDELDSAPAKKAQVKKKRTKDESEQEEAASPKKNNTKKQKVEGTPVKEKKVAF FT AEKLEQGPTGPAAKKEKQQASSNAPSSPKTRTLKGGVVVTDVKTGSGASATNGKKVEMR FT YIGKLENGKVFDKNTKGKPFAFILGRGEVIRGWDVGVAGMQEGGERKITIPAPMAYGNQ FT SIPGIPKNSTLVFEVKLVRVH" FT misc_feature 4382..4657 FT /note="Pfam match to entry PF00254 FKBP, FKBP-type FT peptidyl-prolyl cis-trans isomerases" FT CDS join(5321..5402,5444..6369) FT /db_xref="SPTREMBL:O94756" FT /gene="meu14" FT /gene="SPBC1347.03" FT /product="predicted coiled-coil region; meiotic expression FT upregulated (PMID 11447128)" FT /protein_id="CAB37434.1" FT /translation="MPKSSNLKMQRKGSLRENGLVKGLNKNKFSISKLKELSHADDSRK FT SHRIIRSGKSSGEAYKQAGKGLMNLGNHLSDWGAKSSNLSLNDISDKIGVLVSELGETE FT IEFVKAFNENRIKFKAIRAMEDSIAPSRAHRQRLISSIEREEERDPLSPKLTDLQNQLV FT RTEAENLVGEMQLDNTSREVFKSSFQGLMDAFQLRAQKQMTLSYYASQLAELINDEVAY FT PGDNPAAYSQKYATQIMHQCVESMARLLAPVTSETTEHVGSDCEFTRKSSSSVEFSDHS FT QDSGDPSQQNILQVKNVQAVLSIPEAESYKAQLLSSIAEEQKKKELQAKSTVFL" FT misc_feature 5403..5408 FT /note="gtaaga, splice donor sequence" FT misc_feature 5432..5443 FT /note="ttaatgacatag, splice branch and acceptor" FT CDS 7057..8100 FT /db_xref="SPTREMBL:O94624" FT /gene="SPBC1347.04" FT /product="putative mitochondrial inner membrane protein; FT possibly involved in import of mitochondrial inner membrane FT proteins; translocation channel component; similar to S. FT cerevisiae TIM54" FT /protein_id="CAB37435.1" FT /translation="MLKTIKSYMPGRNMSIFLGFVAGISGAIYYDRRQKNLIIEKYCSQ FT VRHLADQPMAPLELPRKLKVYLHGPPGDGIYVAREEFEEYIRPIFNAAAIEFETVESKG FT EGNLLEQVARTVYNKRHNISEVSEPEKNLLSVLKPSVDPPAIVLLGRHALKEFLYGVRY FT GFSDDIMKRKLETEKLEANNKEEKEEKEGKDDKDDKEDSNDTKNDKKISKNEVDSSLIE FT ASPLTGQVPPKFLDTIAIFPLPNLLGFSNTPKRLSRFFKRRELADELGAIAVNVALSRD FT VTKFPKQDGTLLLAEEETDWPKQFFTRSDLENRIWTAPFLQDSDEIRFFENIDIFDSTK FT AKQDKYE" FT 3'UTR complement(8190..8311) FT /note="mRNA from AB029547" FT CDS join(complement(9449..9567),complement(8417..9393), FT complement(8312..8361)) FT /db_xref="GOA:O94625" FT /db_xref="SWISS-PROT:O94625" FT /gene="SPBC1347.05c" FT /product="DNAJ domain protein; similar to S. cerevisiae FT SCJ1" FT /protein_id="CAB37436.2" FT /translation="MFTNNFSQKQILGVSKDASESEIRKAYRQLTKQWHPDKNPGNEEA FT QEKFIEINKAHEVLSDPEQRKIYDAYGEEGLNGQPGGPGGGPGEGFPGGGFGFDPFGDI FT FDNIFGGRRRQNAVRRGPSMEQIVQIHLSSFYTGGSFTLEIPVKRTCSVCSGQGFNPKY FT SADKAIESCPVCGGSGFRVIEHMIAPGFRQQMRMPCNACNGNGRTIKHKCPRCKGERVA FT EVVESFDIKVPAGAPEGYRIGFRGKADEIPGMEAGDIIVILEAAGGDYGWTRKDNDLYR FT KETISVREALLGNWKRKIQKLDGSFMEVKRSAGEVVHPGETERVKNQGMPIYNLHKGKT FT TSAHGSAYIEWEVKFPKKLKGKFLKDLNNLFEKYDNEFDEL" FT intron complement(8362..8416) FT /note="confirmed intron" FT misc_feature complement(8890..9156) FT /note="Pfam match to entry PF00684 DnaJ_CXXCXGXG, DnaJ FT central domain (4 repeats)" FT misc_feature complement(9352..9540) FT /note="Pfam match to entry PF00226 DnaJ, DnaJ domain" FT misc_feature complement(9394..9409) FT /note="ctaataaatgttctag, splice branch and acceptor" FT intron complement(9394..9448) FT /note="confirmed intron" FT misc_feature complement(9443..9448) FT /note="gtaagt, splice donor sequence" FT 5'UTR complement(9568..9735) FT /note="mRNA from AB029547" FT misc_RNA 10138..10331 FT /note="mRNA from AU013717, not attatched to a CDS" FT 3'UTR complement(10582..10737) FT /note="mRNA from SP06929" FT CDS join(complement(12036..12161),complement(10738..11952)) FT /db_xref="GOA:P40233" FT /db_xref="SWISS-PROT:P40233" FT /gene="cki1" FT /gene="SPBC1347.06c" FT /product="serine/threonine protein kinase; casein kinase I FT (PMID 8125945); regulator of phosphatidylinositol FT 4-phosphate 5-kinase (PMID 9873063); similar to S. pombe FT cki2 and cki3 (paralogs); similar to S. cerevisiae CKI1 and FT CKI2" FT /EC_number="2.7.1.-" FT /protein_id="CAB37437.1" FT /translation="MSGQNNVVGVHYKVGRRIGEGSFGVIFEGTNLLNNQQVAIKFEPR FT RSDAPQLRDEYRTYKLLAGCTGIPNVYYFGQEGLHNILVIDLLGPSLEDLLDLCGRKFS FT VKTVAMAAKQMLARVQSIHEKSLVYRDIKPDNFLIGRPNSKNANMIYVVDFGMVKFYRD FT PVTKQHIPYREKKNLSGTARYMSINTHLGREQSRRDDLEALGHVFMYFLRGSLPWQGLK FT AATNKQKYERIGEKKQSTPLRELCAGFPEEFYKYMHYARNLAFDATPDYDYLQGLFSKV FT LERLNTTEDENFDWNLLNNGKGWQSLKSRNAETENQRSSKPPAPKLESKSPALQNHAST FT QNVVSKRSDYEKPFAEPHLNSASDSAEPNQNSLPNPPTETKATTTVPDRSGLATNQPAP FT VDVHDSSEERVTREQVQNATKETEAPKKKKSFWASILSCCSGSNEDT" FT misc_feature complement(11391..12128) FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain" FT misc_feature complement(11953..11972) FT /note="ctgattgattttgcttatag, splice branch and acceptor" FT intron complement(11953..12035) FT /note="confirmed intron" FT misc_feature complement(12030..12035) FT /note="gtaagt, splice donor sequence" FT 5'UTR join(complement(12306..12339),complement(12162..12262)) FT /note="mRNA from SP06929" FT intron complement(12263..12305) FT /note="confirmed intron" FT CDS join(12939..12978,13060..13145,13265..13330,13393..13743) FT /db_xref="GOA:O94626" FT /db_xref="SWISS-PROT:O94626" FT /gene="SPBC1347.07" FT /product="putative oligoribonuclease; similar to S. FT cerevisae REX2" FT /EC_number="3.1.-.-" FT /protein_id="CAB37438.1" FT /translation="MSNLKQPLVWIDCEMTGLEVGKHVLMEVAAIITDGNLRPVEEKFD FT AVIKLDEKQLSEMNDWCIEQHGKSGLTERCRQSNLTVKDVENQLLAYIKKYIPKKREAL FT IAGNSVHADVRFLSVEMPKIIEHLHYRIIDVSTIKELAKRWCPDIPAYDKKGDHRALSD FT ILESIGELQHYRSYWLS" FT misc_feature 12979..12984 FT /note="gttagt, splice donor sequence" FT misc_feature 13045..13059 FT /note="ctaatatgattgaag, splice branch and acceptor" FT misc_feature 13146..13151 FT /note="gtaact, splice donor sequence" FT misc_feature 13250..13264 FT /note="ctaactaaggcgtag, splice branch and acceptor" FT misc_feature 13331..13336 FT /note="gttact, splice donor sequence" FT misc_feature 13373..13392 FT /note="ctaataaacag, splice branch and acceptor" FT CDS complement(13867..14748) FT /db_xref="SPTREMBL:O94627" FT /gene="SPBC1347.08c" FT /product="conserved eukaryotic protein; low similarity to FT human HEMBA1005185, D. melanogaster CG11164, and C. FT elegans F21D5.6.; conserved motif FT {R/H}S{W/F}{VIY}...V.{S/E}.G.{L/I}{H/Y}..{T/A}P{V/I}{D/N} FT {L/P}; no apparent S. cerevisiae ortholog" FT /protein_id="CAB37439.1" FT /translation="MQGKIFILPKDSTNQQFVELSHPLTGRPLRYLLTNDHLLQILQVG FT DSSKQRSWFVGDHVVSDGYLYVCTPIDLLALVLPIIQELTWSRRKEPNRYVSFEDFIEH FT FDNMGPHYPRVSEVLSPNLLNTLHRICKVNEPVGSLPKTFQLDESSVVKILLRKAKVAQ FT ENLPPSIVTELKKQLAPLDLRTPLPQDLLELSCKWHAASLVCEDLQPEWYNKLAYWQEE FT LAPLHAYTKNLEESRKILVEKEALLNSKKRPQNSDITSSLLKKPNRKQATKKSKYFSGE FT GMTKISSFFTKK" FT CDS 16477..17331 FT /db_xref="GOA:O94628" FT /db_xref="SPTREMBL:O94628" FT /gene="SPBC1347.09" FT /product="putative methyltransferase; similar to S. FT cerevisiae COQ3" FT /protein_id="CAB37440.1" FT /translation="MSDIVYANVSHYNKIEASKYDNPSTLAISKVISSKILQFEDNSET FT SLRHDLPKYDQDRLLLTSDDDLTNVNNFWKKSGMSILDFACGTGLISQHLFPYCKQIVG FT IDVSQDMVDVYNEKFRKMNIPKERACAYVLSLDDLDGNGDEPFSTEFDAVVCSMAYHHI FT KDLQEVTNKLSKLLKPNGRLFVADLIKGGDTFHGNLHPDEIAKLGVAHHGGFTPQSILN FT LFKNASLSNAEVIGKAQANVWVDEAKYQRSTQSKDAKTLDLANGEKLYEVKLQLMVISG FT IKT" FT CDS 18466..20247 FT /db_xref="GOA:O42709" FT /db_xref="SWISS-PROT:O42709" FT /gene="cdc23" FT /gene="SPBC1347.10" FT /product="cell division cycle protein; required for FT initiation of DNA replication; essential (PMID 9745018); FT chromatin associated throughout the cell cycle; similar to FT S. cerevisiae MCM10" FT /protein_id="CAB37441.1" FT /translation="MHDPFIAEENDLDLEEKRLQRQLNEIQEKKRLRSAQKEASSENAE FT VIQVPRSPPQQVRVLTVSSPSKLKSPKRLILGIDKGKTGKDVSLGKGPRGPLPKPFHER FT LAEARNQERKRSDKLKTMKKNRKQSFQRKRNILEDGKSEEEKFPMKCDEIDPYSRQAIV FT IRYISDEVAKENIGGNQVYLIHQLLKLVRAPKFEAPEVDNYVVMGIVASNSGTRETVNG FT NKYCMLTLTDLKWQLECFLFGKAFERYWKIQSGTVIALLNPEVLKPKNPDIGRFSLKLD FT SEYDVLLEIGRSKHLGYCSSRRKSGELCKHWLDKRAGDVCEYHVDLAVQRSMSTRTEFA FT SSMATMHEPRARREKRFRGQGFQGYFAGEKYSAIPNAVAGLYDAEDAVQTERERKERYK FT KQRAQAEREREILVRLSKRCCASSSSSSNSNNLSTGMSMRTLGHQYLNLQGSGVKNLHD FT KGNPTALSKDSEIDSSTKKPSVLASFNASIMNPKSSLPSFSNSAILGTNDAASGTPVPQ FT DTTSTKVSPAVVFTSSPRIFSPQSLRKIGFDPTHSADASTTHSTATGLSRSGSLKNIKF FT RYEFTESDDEDDLEIVP" FT CDS 21234..21554 FT /db_xref="SPTREMBL:O94629" FT /gene="SPBC1347.11" FT /product="hypothetical protein; sequence orphan" FT /protein_id="CAB37442.1" FT /translation="MFSILKQGVISKSLLAATSLKATASRFSFSTSVASRVDGTKNGWS FT FTASNVADQTTDIGINSESAMSCNDQEQPLSFYVQTVRDDLNSPNWGAEQRKGAFDWEV FT SA" FT misc_feature 22737..23825 FT /note="Pfam match to entry PF00022 actin, Actin" FT CDS join(22964..22980,23024..23054,23124..23188,23228..24254) FT /db_xref="GOA:O94630" FT /db_xref="SPTREMBL:O94630" FT /gene="SPBC1347.12" FT /product="actin-like protein; centractin" FT /protein_id="CAB37443.1" FT /translation="MTVTEIFDNQPICIDNGSGFIKAGFAGDDIPKCLFPTCVGRIKHE FT RVMPSSIQKDMFVGSEAQNLRGLLKIQRPIERGIIQNWSDMEEIWSYIYSDQQLNTLPE FT EHPLLLTEPPLANIRNKEKIAEYFYETLNVPALSFSLQPVLALYASARTTGIVLECGDG FT LTHSVPIYDGFSIPSAIQQEEIGGRDVTDYLQLQLRKSGHELVSSAEKEIVREIKEKCC FT YVASDFRSEIESWTEHKPQIHTYQLPDNQTITLGTECFSAPEVLFNPEMMGSEASGLHI FT QLFKSILLSDIDLRSTLYSNIVLSGGSTLLRGFGERFISELRAISGKKNQVKIYASPER FT MHNAWLGGSILASLSTFRRLLITSEEYKNDQNVIFRRRF" FT misc_feature 22981..22986 FT /note="gtgcgt, splice donor sequence" FT misc_feature 23010..23023 FT /note="ttgacgcgttttag, splice branch and acceptor" FT misc_feature 23055..23060 FT /note="gtgcgt, splice donor sequence" FT misc_feature 23107..23123 FT /note="ttgacaaaactatctag, splice branch and acceptor" FT misc_feature 23189..23194 FT /note="gtatga, splice donor sequence" FT misc_feature 23217..23227 FT /note="ctaatatacag, splice branch and acceptor" FT CDS join(complement(25178..25465),complement(24867..25082), FT complement(24547..24820),complement(24376..24503)) FT /db_xref="GOA:O94631" FT /db_xref="SPTREMBL:O94631" FT /gene="SPBC1347.13c" FT /product="putative ribose methyltransferase; similar to S. FT cerevisiae PET56" FT /protein_id="CAB37444.1" FT /translation="MIRSRVNLAREVPKKAKAHLSKERRLIKEDSEFVFGTHSVKNALA FT TRKRECRALYVQNADIHSEFEEFLNKLQYKIPIKSVNKEHLNQITACRPHNGVVLEASS FT LNVPTISDLLFPAGEEYNNKNGQDSPHNDLNEGKSSSSDNYPPLYVYVDGITDPQNMGA FT VIRSAYILGAKGILLSKKHNTFLSPVVSKASAGALEVFNISHVKNPMVFLRNSVLKGWK FT VIGTKPALPDNKDQIYTPHKIKTELMNEPKILVLGSEKGLRTNILTQCSHYVSIPGGDK FT YVDSLNVSVAAGILLYSLVN" FT misc_feature complement(24504..24517) FT /note="ctaactttataaag, splice branch and acceptor" FT intron complement(24504..24546) FT /note="confirmed intron" FT misc_feature complement(24541..24546) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(24575..25027) FT /note="Pfam match to entry PF00588 SpoU_methylase, SpoU FT rRNA Methylase family" FT misc_feature complement(24821..24835) FT /note="ctaattgggtttaag, splice branch and acceptor" FT misc_feature complement(24861..24866) FT /note="gtaagc, splice donor sequence" FT misc_feature complement(24899..25930) FT /note="nominal overlap with cosmid SPBC56F2, EM:AL023288 S. FT pombe chromosome 2" FT misc_feature complement(25083..25103) FT /note="gtattctcactaacatgttag, splice branch and acceptor" FT misc_feature complement(25172..25177) FT /note="gtacgt, splice donor sequence" FT misc_feature complement(25906..25930) FT /note="SPBC56F2.12, see c56F2 for complete CDS" XX SQ Sequence 25930 BP; 8391 A; 4590 C; 4705 G; 8244 T; 0 other; ggcagcttct caatgaactg agcaactgaa attaatgagt tcatcttctt tcgcttccaa 60 acctaatcac attttatgat ggtcgtaatg tgttttaact ttctatctca ataagcataa 120 ttcttttttt ttttgcaaaa gaaaaaattt ttgtagtgac ttatagattt ctttgtcctt 180 tgctctcttt aaaacaataa aaactgtgag gttacgctta tcattgactg gttttagtag 240 ttaaaagaac tacagtggtt acatgtaaac aacataatag atacatttga ttaaaggtca 300 ttattaaaaa gcataaacat atctacttaa gcgcaaaatc tttcccaaaa tccttattga 360 atttggaaaa caaagcatta aaaaatcatt aatggaggta tgtttctctg caaacattct 420 ccttgaacag tttcaattat tttgtcgatg gctttttccc aaggcttatt acattccttt 480 ctattaagtt gatacagcca ctttagcatc atctgtgcct ttcctaggtt tttttcttct 540 cgtataactc tacacacgta atttgcaaaa taattcacat catgaatatt aggtccttta 600 gacgctttac tgtaccattt tgttaacaac cctcgtaaat cctctagcga ttgtacgtgt 660 tgaaatgtga caatatgagg tttctctagc tttacttcag aaatgaggtc cgatttttgt 720 aaattgctct cttttaggat ttgcttctgt aagtcttttg gaagttcctt tagtgttaaa 780 taatcaacgt taggcttgtt aattgttttt gacttcttag aaatttgtaa aagtttatca 840 aatgcatttt cttgccttat ttttttcttt cctcgttcat ctattttatt atccgcgtga 900 gattttaatg acaaacgttt gttcatggca atctcatgat tatcgtttac ttcatttctt 960 ataggagtag gtaattcaac cataaacaaa ggatctaact ggcttggata ttccgtaata 1020 cttcgctttt gcaacctcaa ttgctgctgt atatcagact gcatcgaagg tggtaattga 1080 gctagagcac tggaactgat ttgagaagat gacggcagat catacggtgt tgatggaata 1140 agttttggag acagctgctt cttttgacta attatttctt tatctttact tgatatgtca 1200 acagatgcac cttttagcga cactttattt cgagaagtta tgctctgtat agagcggtaa 1260 tcttttctaa ttttagagtt gtctttaata attttgagag cttgtaatcc tataccacgt 1320 acatctcctg gatcgacatt aattgtttta tacattgagg tcaccttctt ccatattaag 1380 tcaaacgaat tagtagcaga agtaaaagtt gaagattttg taaatgaagt gacttcccca 1440 gctccaaggt actttggtgg actgaaaggg gctccatcag cccttttcaa aatccgaagc 1500 tgaatttgat gcaaaagcac ttggcattta cccattctgg aaagcaactc atgaagcaac 1560 cgttttaaga aatctatccc atcctcttga aaaacgaaac gaacacccca attaacatct 1620 acggatatgg acctccgtgg ggtttcatta ttgattatat cggtatcaat tcctctggaa 1680 atattgtata aatgcagacc gtaatttacc ccaaaagtct cttgaagatt gaatttttca 1740 attctttgca gctgcccaat agtacgcaca ccgtacaaat taaaaagttt ctgcgcttgt 1800 gaagagccca cccctggtaa atcttgaaca gacaaaggac tcaatacatc aaaaacattt 1860 tctattgaca aagaataaac gttgtgaggc ttcgccttcc taagtgcaag tcttgctaag 1920 agaacatttg ggccaatacc aacgctaact tcgcaattgg ttttctcgcg aacctgcgag 1980 cggatagact cggcaatctc aaagcaatct tgaaaagatg aaacactaga agttatatct 2040 agaagagcct cgtctatact tataacctta atatagtcgt gaagtgtatt aacaaggata 2100 gtgtaaaatt ctctagaaac agattcgtat gctccaaaat cataatcaac aacccgtaat 2160 gaaggacaca ggtttttagc tgttccaacg tacataccat tttttatgcc aaacttccga 2220 gcctcataat tacaactagc tatttcggaa ttttttatac catgagcaac agcaacgggc 2280 ttcagtcgta gctcatgaga aaagcgtgtt gaaacggaag caaaaaagca atcaaaatca 2340 acatgaagaa ggaaacgaga tttttttgat ttatctttca taattggacg aacaggttca 2400 gaagcagtag tcattgcttg gatttcattt ttaaaatcag ctttccaagt acttaagtga 2460 tgtaaacgag aggagctaaa gaaattctca agaaaatctt gattttgagt ggttgaattt 2520 cggacattgg gattttttaa caattgatag ttgtgcagtg aagacgctga taatccactc 2580 aaatcatcta aaaatccctt tgctttactc tcttttgttt tatctttttc attatcatgt 2640 tcttcttcct gcgagcttgt ttgaatatct tctaagttac cttcgggttg gctaggttta 2700 gaggcgacaa aagaaagggt agcttgagcc gatgaagctt gaaaggtacg ataatttatc 2760 cacggaagaa ttttcttctg tttgatgcaa tccactatcc attctggttt aaccactttc 2820 tgatgcttcc attggcgagc tttggaagga gtgagaaatg aacacaccaa atatgatatg 2880 cttgtttttc catcaacata ttgtataaaa gtacctccat ttgaaactat catttgccgt 2940 aattcggtat aagacggctt tgtatatcca ttaatcgcta ttgcaagtcc atgaaagaga 3000 tcagatttag aatcttcatc aatacttttg tatagagcgg cattttgatt ttgaagcttt 3060 ctttgtttcc gggaaaaata atctgcatag tcgtggaacc caacactttc gtatgcctca 3120 tcgtttgctt cgtcaaagtc tgcaatccct actgggcgtc gacgcttcct ttgattaaaa 3180 gccatccagc gcgcttctca ctttcagtaa atataagtat taatatgttt ctgaaaggaa 3240 aataatacaa ataataatgt agccacttaa gcggaaaaag tgtaattaat aaacaaacaa 3300 tgtttataaa gaaaaactaa ctgcaagagc ttttttcttt cattatttaa ccttatccca 3360 aaactcgtga agccaaacta tttcaaagta aaaaacaacg aaatatcaaa aataattact 3420 acgcgtttgt tgtgatgcac gctcgtccaa atttaattaa ttttgagtat aatttgcaaa 3480 tcgcggtaat acgcactacc cttacttaat ggaatacaca acggtttatg tatcaaaatt 3540 ttttacatcc tctaccacct cacctcttag gcaagaataa gtcatgtctc ttccaattgc 3600 tgtttatagt ctttcggtaa agggaaaaga tgttcccgct gtggaggaat ctacagatgc 3660 atctattcat ttgactatgg catccattga tgccggcgaa aagtctaata aaccaactac 3720 tttattggtg aaggttcgtc cccgtatccc cgttgaagat gaagatgacg aagaacttga 3780 cgaacaaatg caagagcttc tggaagaaag ccagcgtgaa tttgttttat gtactttgaa 3840 gcctggttcc ttataccaac agcctttaaa tttgaccatt actcctggcg acgaagtctt 3900 cttcagtgca tctggcgatg caaccatcca cttgtctggt aactttttgg ttgacgaaga 3960 agatgaggaa gaggaagaat ctgacgagga ttacgatttg tctcctactg aggaggatct 4020 tgtcgagact gtcagcggtg atgaggaaag tgaagaggaa tctgagtcgg aagataattc 4080 agcatctgag gaggatgaat tggattcagc tcctgctaaa aaggcacagg ttaaaaaaaa 4140 acgtactaag gatgaatccg agcaagaaga ggctgcttct cctaagaaaa acaataccaa 4200 gaagcaaaag gttgagggta cccctgttaa ggaaaagaag gttgcatttg ccgaaaaact 4260 tgaacaagga cctactggtc ccgctgctaa gaaagaaaag caacaagctt cttctaatgc 4320 accttctagt cccaagactc gtactttaaa aggaggcgtg gttgtaactg atgttaaaac 4380 tgggagcggt gcgtctgcta ccaatgggaa aaaagttgaa atgagatata ttgggaagct 4440 cgaaaatgga aaggtttttg acaaaaacac taaaggtaaa ccctttgctt ttatccttgg 4500 tcgtggtgag gttattcgcg ggtgggacgt cggcgttgct ggaatgcaag aaggcggtga 4560 gcgtaagatt acaattcctg ctcccatggc ttacggcaac cagagcattc caggaattcc 4620 caagaattct accttagttt ttgaagtcaa gcttgttcgc gttcactaaa ttttcatgtt 4680 gaagatgaac atactttaac tcccgtgttt aagaagatcg cggattaaac tatgtattct 4740 attaactctt tttatcgcct atctttttct taggtttcaa aaaaaatcag ggtatcattt 4800 tgtatttgag ttaggaaatt tttttttagt taagtgttac aaacactttg gatataggac 4860 ttttggatga tttggattgt tgggtgataa aggagatata atcaatatac aattttttag 4920 aaagagctgt ttgtatgtgt atgagcatta agagaaaaga gaatagcgct tccttgatcg 4980 atactagtta aggatgttta aattatggaa ttttgagttt gagtaaatat aaacgagaac 5040 attccgaaaa actctattaa aagtaaaaaa aaacatattg ataataaaag agccattatc 5100 tgattatcgc taaataagtc tacaaacagc tgtttgttta cgaaattctt aaaattaatt 5160 atcgtaataa tcaacttaaa aaaaaacaag cagttttaga atttaaagaa ttatttttat 5220 tatttgtctt ttttctatat tgtttatttg aaaattgtgc ttctgtttac aggcaaatct 5280 taaggcgggc atatattttt ctgaaacgta aacaatcaac atgcccaaat caagcaactt 5340 gaaaatgcag agaaaaggct ctttaagaga aaacggtctc gtgaagggtt taaataaaaa 5400 tagtaagata taaattggtg tgataaataa gttaatgaca tagaattttc gatcagcaag 5460 ttaaaagaac tatctcatgc agatgactca aggaaaagtc accgcatcat tagatccggt 5520 aaaagttcag gtgaagctta caagcaagct ggaaaaggat taatgaacct tggtaatcat 5580 ctgagtgact ggggagcaaa atccagtaat ctgagtttga atgatattag cgataaaatt 5640 ggagttcttg ttagtgaact gggagaaaca gaaatcgagt ttgttaaagc attcaatgaa 5700 aacagaatta agttcaaagc cattagagct atggaagata gcatcgcacc ctcacgagca 5760 catcgacaac gattaatctc aagcattgaa cgtgaggagg aacgagatcc tctttctcct 5820 aaacttacag atttacaaaa tcaattagta agaacggaag cagaaaattt agtaggagag 5880 atgcagcttg ataatacttc tcgagaagta ttcaagtcat catttcaagg attgatggat 5940 gctttccagt taagagcaca aaagcaaatg actttgagtt attatgcaag ccaacttgct 6000 gaattgatta atgatgaagt ggcttaccca ggggataacc cagctgctta cagtcaaaaa 6060 tatgcaacac aaattatgca tcaatgcgta gagtccatgg ctcggcttct tgcaccagta 6120 actagtgaaa ctactgaaca tgtaggttca gattgtgaat ttactagaaa atcgtcttcc 6180 tcagtggaat tctcggatca tagccaagat tctggagatc caagtcagca gaatatcttg 6240 caagtgaaaa acgttcaagc agtgctttca atccctgaag ctgaatctta caaggcccag 6300 ctactttcct ctattgcaga agagcaaaag aaaaaagagt tgcaagcaaa atccactgtt 6360 ttcttgtagt tatcataaca aactaagaaa cgtcaatcgg attctcaacc caaaaaacat 6420 gtatgtctta gcatgtcgat taattgaagt aaactaaatt caatatattt atccaattga 6480 tccttccaaa gctttagtag atagcatggt taagttgttt gatttcttta tagaaagcat 6540 cttgaaacca ataatggagg atgtttattt ggtctctact tatttaattt atcgtatcct 6600 taaaatttat tgttccaatg agaacttagt actatcgtac aaaaatgtcc tcaaacagaa 6660 ttctcaatat ccctgttcca tttttatctt ttcaaataat aaaaataaaa taaaaaaatt 6720 agatttcctc ttaggccttt atttttgctt aatgggataa ggttgcctcg agaggttgta 6780 tctcatatac acaaggtaga acttttgcat accccaattt acttaactac ttggattttg 6840 gaagttggtg gaaaacttct ttcaaaaatc aaatattcac tattacaacc ttcttaattt 6900 tcattttgac ttttagaagt tttccttttt gaaaatccat atattgattc gcaaataaac 6960 gtgtgtattt catttgtgtg agttcgcata tttcatgttg tgaactttaa aaagagggag 7020 aaaccgatag atacgttttt tggtttgttt ttcacaatgt taaaaacaat aaagtcttat 7080 atgcctggtc gaaatatgtc catatttttg ggattcgtgg caggcatatc tggagcaatt 7140 tattatgatc ggcgtcagaa aaatttaata attgaaaagt attgctctca agtacgccat 7200 ttggctgatc aaccgatggc acctcttgag ttaccgagaa aattgaaggt atatcttcat 7260 ggacctccag gggatggaat atacgttgca cgggaagaat ttgaagaata cattagacct 7320 atatttaatg ctgcagccat tgaatttgaa accgtggagt ccaaaggtga agggaattta 7380 ttggaacaag tagcgaggac ggtttacaac aagaggcata acatttctga agtttctgaa 7440 ccggaaaaaa acctcttatc agttttaaaa ccaagtgttg atcctcctgc tattgtttta 7500 ttaggaaggc atgccctcaa agagttcctg tacggcgttc gatatggatt ttccgacgat 7560 attatgaaaa gaaaacttga aacagaaaaa ttggaagcca ataataaaga ggagaaagaa 7620 gagaaagaag gaaaagatga caaagatgac aaagaggata gtaatgatac aaagaacgat 7680 aaaaaaatta gcaaaaacga agtagactct tctctgatag aagcaagtcc gttgactggt 7740 caagttccac caaaattttt ggatactatt gctatttttc ccttaccaaa tcttttaggg 7800 ttttctaaca ctcctaagcg actttcaaga ttttttaaaa gaagagagct agctgatgaa 7860 ttaggcgcaa ttgccgtaaa cgttgcatta agcagggatg taactaagtt tccaaaacaa 7920 gacggcactt tacttctagc tgaagaggaa acagattggc cgaagcaatt ttttacaaga 7980 tctgatttgg aaaaccgcat ttggacagct ccctttctac aggactctga tgagatacgt 8040 ttttttgaaa acattgatat ctttgattca acgaaagcca aacaagataa gtatgaatga 8100 agtgatgtct attctaaaat ttgaagaata aaacaaatat atgaaattaa gtactgtgta 8160 tgaagaatta ctaggtagcc ataaacagta aaaggaaaaa taaaagaatg gcgtatttat 8220 gtatataaga tagtcaacag taaatgcaaa ggattttggt aaataagcta gttaaattaa 8280 aaacgtagca gcggcttcaa aaaactccgt tttaaagctc atcaaattcg ttatcatact 8340 tttcaaataa gttattgagg tctgaataca ttggttagtt taacaaaact tatatagtct 8400 gcgagatgta acataccttt caaaaacttt cctttcaact ttttaggaaa tttgacctcc 8460 cactctatat aagcacttcc atgtgcagaa gtggtttttc ctttatgaag gttgtaaatt 8520 ggcattcctt gatttttcac tctctccgtt tccccaggat gcacaacttc gccagctgac 8580 cgcttaacct ccataaagga tccatccagt ttttgtattt tacgtttcca atttccgagt 8640 aaagcttccc taaccgaaat agtttccttt ctatatagat cattatcttt tctagtccat 8700 ccataatcac caccagcagc ctcaaggata acgatgatat ctccagcttc cataccagga 8760 atttcatcag ctttaccacg aaaaccgata cggtaacctt caggagcacc agctggtact 8820 ttaatgtcaa agctttcaac aacttcagca acacgctcac ctttgcagcg agggcattta 8880 tgcttgatcg tacgtccatt tccattacaa gcgttacatg gcatacgcat ttgctgacga 8940 aaacctggag cgatcatgtg ttcaatgact ctgaaccctg aaccaccgca aacagggcaa 9000 ctttcgatag ctttatcagc ggagtattta ggattaaagc cctgaccact acaaacactg 9060 caagttctct tcaccggaat ttccaaggta aaactgcctc cggtgtaaaa agatgaaaga 9120 tgaatttgaa ctatttgctc catgctaggt cctctgcgaa cggcattttg acgtctacgt 9180 ccgccaaata tgttatcgaa tatatcacca aatggatcaa atccgaaacc tccacctggg 9240 aatccttcac ctggaccacc accaggacca ccaggttgac cgtttaatcc ttcttctcca 9300 taagcatcat aaatcttacg ttgctcagga tcagaaagga cttcatgggc cttgttaatt 9360 tcaataaact tctcctgtgc ttcttcatta cctctagaac atttattagc tttaggcttt 9420 catttgtttg catgcttgtt taacttacgg atttttgtca gggtgccatt gtttcgtcaa 9480 ttgtctatat gctttgcgaa tctcagattc agatgcatct ttactgactc caaggatctg 9540 tttttgagag aagttgttag tgaacatttt tctttaattt tcttctcaat cctacgatca 9600 catgcactta cttgatagta gtcagcagca gatacaactg cttgaatgca aactaaaaat 9660 cctaatataa aatgaaaaag attgaaatgc attaactatg tttaggaagc gagttggagt 9720 ttagctcact ttaacaaggg aatggtatta tgtagaaaga ttttcttgaa gaaatccagg 9780 acaagtttgc aacgcctcgg tatactcatc gccgtggtta tcgaaaccat aaatttaatt 9840 taacattgtt tagaaatgtc ataaaagtta ctatatgaaa atatttttat taatacaatt 9900 aatccatttc aaggatccac ataggttatt taaatagtcc aaatagttga taattttata 9960 tttgtttcaa cgaatatcgg gtggaattgt tggtagcaat atttcgaaat atttttacat 10020 gctaatttta ttactaaatt ttttagttcc aaaaaccaac tactcattat ttcagagggt 10080 aagtatgcct ttagtcattt gaggcagagt aaggatgata aataataata taatatctat 10140 gtacacgtaa atacatatac acataatata tataatatag atagatagat gtgggtgttc 10200 aaacctctac acatatgtac gagagtccaa ataactaaaa atagactgac aagcagtatt 10260 caacgacctt tatgctcaag gaacgcataa tatcatcgga agtgatcaaa agacaaaatg 10320 ttgaacgaga caaagattat aaacggaaaa aaacataaaa gcaaagaacc tgtgcaaata 10380 taagatatca ttgctttaat cacaataagt aacctccagt ttgacaatac gcgaagaagc 10440 ctaaagaaaa gtaattattt caaacgtaca ttttacagat ttataaaaaa ggatagatta 10500 ccgggaagga agaaaaaatg caaaagttaa ccctgctagc aattctaaga agaaggattt 10560 ggacaaagaa ataaaatgaa aagaaagtgt ataattaaat gaatgaagca cagaaaatcg 10620 ttacggcaca aaaaataaat cacaaaaaca cttttgtcaa ctgaaagcct gattatccat 10680 accagtctga agaacaaaat aatcaagaaa ttcctaaata ctagtagaac atattattca 10740 tgtgtcttca ttggagccag aacaacaaga aagaatactg gcccaaaatg attttttctt 10800 tttaggtgct tctgtttctt tcgtagcatt ttgtacttgc tctcgggtaa cccgttcttc 10860 agaagaatca tgaacatcaa cgggtgctgg ttgattagtt gctaaaccgg aacgatcagg 10920 cacagttgtg gtagctttcg tctccgttgg cggattaggt aaagaatttt gattgggttc 10980 agcagaatcg cttgcagaat tcagatgcgg ctcggcaaaa ggcttttcat aatcagagcg 11040 tttggaaact acgttctgag tacttgcatg attttgcagg gctggtgact ttgattccaa 11100 tttgggtgct ggtggtttgc ttgaacgttg attttctgtc tctgcgtttc gcgacttcaa 11160 gctttgccaa cctttaccgt tattcaatag attccagtca aaattttcat cctcagtagt 11220 atttaatcgc tctaggactt tcgaaaatag gccttgcaaa taatcataat ctggagtagc 11280 atcgaatgcc aaattacgag cataatgcat atacttgtag aattcttccg ggaaaccagc 11340 acacaactcg cgtaacgggg tactttgctt tttctcacca attcgttcat atttttgctt 11400 attggtggca gccttcaatc cttgccaagg taggctacct ctaagaaaat acatgaatac 11460 atgacccaag gcttccaaat cgtctcgacg ggattgctcc cgacccaaat gagtattaat 11520 agacatgtaa cgagcagtac ccgagaggtt ctttttctcc cggtaaggta tgtgctgttt 11580 ggtaactgga tcacgataaa attttaccat gccaaagtct actacgtaga tcatattagc 11640 atttttactg tttggtcgac cgatcaaaaa attatcaggc ttaatgtctc gataaacgag 11700 actcttctca tggatagatt gcactcttgc caacatctgt tttgcggcca tagcaactgt 11760 ttttacacta aatttacggc cgcagagatc gagcaaatct tctaaacttg gcccaagaag 11820 gtcaatcacc aaaatgttat gtaacccttc ttggccaaaa taataaacat tcggaatacc 11880 cgtacatcct gccagcaact tgtaagtacg gtattcatca cgtaattgag gagcatcact 11940 gcgtcttggt tcctataagc aaaatcaatc agtaatgaag gaaacaagaa aaatatccag 12000 cttcaaagca tggcatcaaa tggattctca cttacaaatt taatggctac ttgttgatta 12060 ttcaacaaat tcgtcccttc aaaaataaca ccaaacgagc cttcgccaat tcttcttcca 12120 actttgtagt ggacaccgac tacattgttt tgtccactca ttatctttga acgatttgtg 12180 ctggagattt gtcaaatatg atgtctccgt tttccgctat cgaatgcaaa aaactaggtt 12240 gtaagcgatt cctgtttaaa tacttttatg aattagattg aatcacaaag atctcctata 12300 caaaccttga aattacaact attcaagccg ttattgagaa aagaggtgga tggtgttgga 12360 acggatgttt ttagtggtgc tttagttacg gaagtgtcat gtgcatcact tccctctatt 12420 cctgcctgat taaggggtta ggtaatgctg tctttggaat acaaacactg tttcaaaacg 12480 tttaaataaa catactatta ctagttttca ttgcaaaaat caatcgatag ctaagttttt 12540 aattttaaaa aatcccggat attaaaatcc aacttacaac gaagtacttt cattaagtaa 12600 taataccgta ttttcatatg caaggtgcat tcttaaataa tagaatcatt ttgcagtcat 12660 atcacattaa aaaacgcttg tatagcaaac gcactagctc gttgcattcg cgcttcttgc 12720 agccaacata tcgcaaaaat atttgtcaaa tttccaaacc cattttccag caagacttat 12780 caacgaatac gagtatgttt agattcagtc tatcaagtta tcatttctac aatttacatg 12840 tttaagtttc tttttgtcga tgtgtacctc agtttttaaa cttttactaa tataaagatt 12900 tcatctcaaa attgaaaagt ccattctcca acctcaaaat gtcgaattta aagcagcccc 12960 ttgtttggat tgattgcggt tagtgagctt tagtataatc ttagctttta aaatgcatta 13020 cgatggtttt ataggtaact tgtactaata tgattgaaga gatgaccggg ttagaggtgg 13080 gaaagcatgt attgatggag gtcgcggcaa tcattactga tggaaatctt cgccccgttg 13140 aagaggtaac ttttaattgt gaacattgaa acatcggctt ttaacttgag atgtttcaag 13200 agaaacaaat gcatggtttc gaagttgagc gtttattaag gctgtcatac taactaaggc 13260 gtagaaattt gatgctgtta ttaaactcga cgaaaagcaa ttgagtgaaa tgaatgactg 13320 gtgtattgag gtatcttttc ttgcttttag ttcattcacg gatgtcaatt ttctaattat 13380 actaataaac agcaacatgg gaaaagtggt cttacggaaa gatgtagaca gagtaattta 13440 acagtgaaag acgttgaaaa ccagttgtta gcatacatta aaaaatacat tccaaaaaaa 13500 cgagaagcgt taatcgctgg aaacagtgtc catgcagacg taaggttttt atctgtcgag 13560 atgccaaaga taatcgaaca tttgcattac agaattatcg atgtttctac tattaaggaa 13620 ttagccaaac gctggtgccc ggatattcct gcttatgata aaaagggtga tcatcgcgca 13680 ttgtcggata ttcttgaaag tattggtgaa cttcaacatt accgctctta ttggctttct 13740 tgaaacattg ctcaagaaag aagaattcca cttttacagc aattgacaat atcttgtaaa 13800 catgccaaaa aaattaaggg tactatgcta agaaaaaaat aaaagcaaaa tcatacctcg 13860 gtgatcttac ttttttgtaa agaatgaaga tattttcgtc attccttctc ctgagaagta 13920 tttggacttc ttggtggcct gcttccgatt gggctttttt aaaagacttg atgtaatatc 13980 actgttttgt ggacgttttt tagaatttaa caaagcttcc ttttctacca aaatctttct 14040 tgattcttct aagtttttag tgtaagcgtg cagtggggcc aattcttcct gccagtaggc 14100 taatttgtta taccattcag gttgaagatc ttcacaaacc aatgaagcgg catgccactt 14160 gcatgacaat tctagtaaat cttgtggaag cggcgtgcgg aggtccaaag gcgctaactg 14220 ttttttaagt tcggttacaa tactaggggg aagattttct tgagcaacct tggctttcct 14280 tagtaaaatt ttaacaacag aagattcatc cagttgaaag gtcttgggca aagatcctac 14340 tggctcgttt actttacaaa tccgatgtaa tgtgttcaac aaattcggag agaggacttc 14400 tgacactcgt ggataatgag gacccatatt atcaaagtgt tcaatgaagt cttcaaacga 14460 gacatatcga ttcggttctt tccggcgact ccaagtaagt tcctgaatga ttggaagcac 14520 aagcgcgagt aagtctatcg gggtgcaaac atagagatat ccgtccgata ctacatgatc 14580 ccctacaaac caagaccttt gttttgaaga atccccaact tgaaggattt gtaaaaggtg 14640 atcgtttgtt aataaataac gaagtggtct cccggtcaag ggatgtgaga gttcaacaaa 14700 ttgttgattt gtagaatctt tgggtagtat gaatatcttt ccctgcattt tttaagttta 14760 aattatgaaa ccccaaaatt tgtgaggcaa tcacgtctga aacttcgtac cactatttgc 14820 aacaaaagta aaaaatgcaa agatatcaat tgaaaacaac tctgagtact tgcaaacaca 14880 attttttaat tagaaagatt tcgttgtgta actttcagct aaagatgagt attttgtaaa 14940 agtattgaca acgatttggg tatatcaaaa tttaaaacag tgacgactct agttgtacat 15000 atacgaaaga aattaagcat ataaaattga ttgttcctct taagataatc atgaagttga 15060 tataaaagat ggctgaagta agaggagatt cgtaccgact ttttgttgtc tgttcaagac 15120 acgttgttag tcaagaactc catctttata agaaagcagt acaaaaaaat gaaatgcata 15180 ttcttaaaaa agaaatataa cagtcgatgt tgaagtcaag agcggcaatc ttagttatga 15240 gaaattcaat ggtaaaccac ggtagtgaat tgaatagaaa gcttgcggct tcaagtacca 15300 aaaaaaaaca gcattggtta aattgaaaag ccaaagtata gatatcctta ataaactaat 15360 aaaatagaca ttgagtattt tctcatctta ataattgcta gattgactat actaactgtt 15420 tatcacatcg aatttttttt tttttaatga aaaaaaactg gttgcggacg ttatacataa 15480 agagtgtata atggtgaaca agactaagtc tacatgttct actacgttga ttgtaaagta 15540 atgaaaaacg tgaagtacat tagttgaaaa ttagtgaagt aactaaaagc gaacgaatat 15600 gaccttcctt gcttgcaagt acctcaaagg tggttgatgt gttatttaaa ccattgatga 15660 atgaatcttc ctcgtgtaca ttctttcggt gtaagtctca aaatgggtta taacattatt 15720 acattgctac cgcatttttt gtgacatgaa tagatcaact tccaaattac tgtttcatta 15780 gcgaagctcc tttttgtatt tttacttaac agtaaatact tacagtgatc tgagcaattt 15840 atggagcctt tcttgcgggc cactttgaga gccatgcagc aagtcagcta gactaacaat 15900 ttaggccaaa tgattcgtac tttttaacga atatcttgaa tcatgcttaa ttgcttcatt 15960 taacacccta cctagggatt tactcaaaac gattcatgta aacaatactt tacaattcaa 16020 tgcaaatagt gtgttggaac gaaacccaat ttagcttctt aaattatgcg cagcggtttc 16080 cagtagtata taaaaagtcc aagcttattt acaaaattcg ggtattaggg taatacaaaa 16140 atgagcgtta tacaaaagca aaaggacggt cacaggaatc ctaatctgtc gaatacaata 16200 atttagttaa aataagaagc tactgaagtt tctatattaa caggctcttt tctgtctaac 16260 atccaataat agttctaaac aaattctcgc ttaataagtt ttagttatat taatcataaa 16320 aagggaaatt gtgctaatct ttcataatcg tggtaccttg tgacataaat tttcagtcat 16380 aaccatttaa agatagtcct tgattatctt tttttttaat attcctatta gcaagacttc 16440 accgttcatt aacaatataa aaggaactaa aatatcatgt cggatatagt ttatgccaac 16500 gtgtctcatt acaacaaaat agaagcatcg aaatatgaca atccaagtac cttggcgatt 16560 tccaaagtga tttcttcaaa aattttacag tttgaagaca attccgaaac cagcctaaga 16620 catgatctcc caaaatatga tcaagatagg ctgcttttaa cttcggatga tgatttgaca 16680 aatgtaaata atttttggaa gaaaagtggt atgagtatat tggattttgc ttgtggaact 16740 ggtttaatta gccaacacct gttcccttac tgtaaacaaa ttgttggcat agacgtttcc 16800 caagacatgg tggacgttta taatgaaaaa tttagaaaga tgaacattcc caaagaaaga 16860 gcctgtgcat atgttttaag tttggatgat ttggatggca acggcgatga accattttct 16920 actgaatttg atgctgttgt atgctccatg gcatatcatc atatcaagga cctacaggaa 16980 gtgactaata agctttctaa acttttaaaa cctaatggtc gattatttgt cgcagattta 17040 ataaaggggg gtgatacttt tcatggtaat ttgcatcctg atgaaatagc taagcttggc 17100 gtagctcatc atggtggatt tactccgcaa tcaattttga atttattcaa aaatgcatct 17160 ttgtcaaacg ctgaagtcat tggtaaagct caggcaaatg tgtgggtcga tgaagctaag 17220 tatcaacggt caacccagtc aaaagacgct aaaaccttag atttagctaa cggagagaag 17280 ctgtatgagg taaaattaca gctgatggtt attagtggta tcaaaacatg atccccttaa 17340 tttttaatta gggataaaca aatgaatggt ctgggtaccc gattttagaa ggtgaagcaa 17400 tcagaccagg aattgcttca tttaaacaag tattgatgtc cattaaattg atagcttatg 17460 ataacttata acactgtgag tcccggtgat tcatttaaac gaaactacat actgagcatt 17520 cagaaaggac taaacttcat tgaaacgaca atttcgaata tgatcaacca aatattatgt 17580 gggattacag gcttttttta tacaatactg gaaatttcgt tatatgattt ttcttcataa 17640 gttggtttca aaagaactgg ccaactgttg tcacaaagat tttaatatta agcgcaaatt 17700 tgaatagaca acggaaacta ggcaatctct tccaccaaat gtaaaaaaaa gttcgacgtt 17760 taaaatttaa ctgttcaaaa tacccctttt aaataagtta ctatatgcat ttgaatactg 17820 tagacacatc ttttatgatt ctatatagac aaatatcgta agtttatatt atgtaaatga 17880 attcgtgata tcgaacgtgt atactcatta aattagcgca tctattttaa ccttttatta 17940 ttcaaactgc agttatgttg tttacctata gcatgtgtag tatagagagg atttaatttt 18000 gcacattatg cttgtttatg cactacattt tgcatcctta aacacatgtc ctttagatgt 18060 ccgctaactg tttacattcc tatatgttta accgcgattt ttaagtattg gaaaataaga 18120 atatcttgtt aaaaagattt ataattatta cttgcttcct tttccaggac taaagaattt 18180 cctgtttttg gcactaaact tttcaacaat atcttcgcat ttcaaaatac aaatgtggca 18240 gtattaaatt tatcctgtta tttgttttgg ctactcatac aatagagaag aaaattttat 18300 tgatcagagt ttttttaatt tcctgaaaag ctagttttct agggttgggt tgaaaagttt 18360 cagtattcgt gagaaattga ctatatctaa caggcggggg gtttttttta tcattgactt 18420 tggaggttta agattaagag gaaaccaagt ttaattaatg caagtatgca tgatcccttc 18480 attgcagaag aaaatgactt ggacctggaa gaaaagaggt tacagaggca gctaaatgaa 18540 attcaagaaa agaagcgtct acgaagtgct caaaaggagg cttcttcgga gaacgctgaa 18600 gttattcagg ttccaagatc tcctcctcag caagttcgtg tccttacagt cagctcgcct 18660 agtaaactaa aaagtcccaa gcgattgata ttaggaatcg ataaaggaaa gacggggaaa 18720 gatgtttcat taggaaaagg gcctcgaggg cctctaccaa aaccatttca cgaacgactt 18780 gcagaggcaa ggaaccaaga aaggaagagg agcgataaat tgaaaacgat gaaaaaaaat 18840 agaaagcaat cgttccagag gaagcgaaac atacttgaag atggaaaaag tgaagaggag 18900 aaatttccta tgaaatgtga tgaaatcgat ccttattcaa gacaagccat tgttattcga 18960 tacataagtg atgaggttgc taaggaaaat atagggggaa atcaagttta tctcattcac 19020 caactactca aactagtaag agctcctaaa tttgaagcgc cagaagttga caactatgta 19080 gttatgggca ttgttgccag taatagtgga accagagaaa ctgtgaatgg gaataaatat 19140 tgtatgctaa cactgactga cttgaaatgg caactggagt gcttcctgtt tggaaaggcg 19200 tttgaacgat actggaagat ccagagtggt actgtcattg cgcttctcaa tcctgaagta 19260 ctaaagccaa agaacccaga cattggacgc ttttctctga agctggattc tgagtacgat 19320 gtacttttag agattggtcg ctccaaacac cttggctatt gttccagccg aagaaaaagc 19380 ggtgaactat gtaaacattg gctcgacaag cgtgccggag atgtatgtga atatcacgtt 19440 gacctcgctg tccagcggtc catgtctacg cgaacggagt ttgcttcaag tatggcgact 19500 atgcacgagc ctcgcgcacg acgtgaaaag cgatttcgtg gacaagggtt ccaaggatac 19560 tttgctgggg aaaagtattc cgcaattcct aacgcagtag ctggtttgta tgatgcagaa 19620 gacgccgttc agaccgagag ggagcgcaag gaacgataca aaaaacaacg agcgcaggct 19680 gaacgcgagc gtgaaatttt ggtgcgatta tcgaagcgat gttgcgcttc ctcttcgtct 19740 agctctaact cgaataacct ctctacggga atgtcgatgc gaacactcgg ccatcagtat 19800 ctaaatttac aaggttccgg cgttaaaaat ttacatgaca agggtaatcc cactgctctt 19860 tctaaagata gcgaaattga ttcatcgacg aaaaaaccat ccgttctggc ctcttttaat 19920 gcatctataa tgaaccctaa atcctctcta ccatcttttt ctaactctgc tattctcggc 19980 actaacgatg cggcatcagg gacacccgtt ccacaagata ctacatccac caaagtttcc 20040 ccagcggtag tgtttacctc ttcgccgagg attttttccc cccaaagtct acgaaaaata 20100 ggtttcgatc caacgcattc cgcagatgca tctacaacgc actccacagc gactggactt 20160 tcacgatccg gctccctaaa aaatatcaaa ttccgatatg aatttactga gagtgatgat 20220 gaggatgact tagaaatagt tccctgaatt ttacgttgtt tttctataca ttatgatgaa 20280 aattaattat ttaaattact aaccaactta ctaattaatt agctagctaa tggatatagc 20340 tatgatttca aatgaatgtt cttttgttta catgcgacac actttgctat catgaaactt 20400 tcaacccttt gttaaacctt tcttctaaat cctaatcctt agtaaatccc aatggaatat 20460 ttgaaacgct tattaaacac agtcgctctt ttcatttgtg atgtcaactg tttgaattca 20520 atgtgcgaag tctccctttt ttgttctgct agcttctctc tcatacaaga acggccgtta 20580 cagcttttga catcacattg tttattaatc aaacgaacgt aagcttactt tcatatggta 20640 tgatgggctt gtaagcaata ctaagatagc cagccaaact gaggtactgt cgacaccttt 20700 agcttacgat tgctttcgtc taggtatcgg actttacact gctagtcgcc tattttaacg 20760 ttgcgccgta tggaacgggt atcgcattct tatcagtaag gaaagctatc tgaattcgtc 20820 acaaaggaaa aggcaaataa atagtctaaa actatataaa tgcgggcttc catctaagag 20880 acctcgccat ccaacaattg ttgcgtccca cctaaacagt gtctaatcaa agtcaattgc 20940 gagacattct aaagtaaaaa gttaatacat tttagctact actaaatact tcttttgata 21000 ttctttttag tgaacaataa agaatattgg tttgatcaac acggtcatct tcagaaaaaa 21060 aattttttat tcgttggttt aattagttaa gaaaattttt tttttctttc ttcgctgacg 21120 tctcgataat taaatctgcg aacggtgata cttctattct acacatttct atttaatcac 21180 tgttattttc ttttcttttt aatttcatca ataaacattt ttgattcatc gctatgtttt 21240 ctattcttaa acaaggtgtc atctccaagt ctcttttagc cgctacctct ttaaaggcaa 21300 cggcttcaag attttccttc tctactagtg ttgcttcccg tgttgacggt actaagaatg 21360 gttggtcttt taccgcatcc aatgttgctg atcaaaccac cgatatcggc attaactctg 21420 agtcggctat gagctgtaac gaccaagagc aacctctttc cttttacgtt caaactgtca 21480 gagatgactt gaactctcct aattggggag ctgagcaaag aaagggtgca tttgattggg 21540 aagtaagcgc ttaaacccga atattgtata caagaagaaa acccgatttc cgttatgatc 21600 agaagaaaat aataaaaagg gaaaacaaaa aattggaaaa ttgaatgttt tatcttattc 21660 gataaaagca ttaaacaatc taacaatgca atctttttta attcgttatt ttcgcttttc 21720 tttttttttt actcttcttg atgtaattgt taagacatgg attttatttt tatttttcta 21780 aggaatttcg attattggaa ttcttttacc acccccatcc ctctttttat taccagtttc 21840 aacacattgg ttcccctgct ttagaatgtt tatcgatata agccgtgaac ggttccttgc 21900 ttttaccatt tttaaatgag gcaagacata tgtattatta gtttataccc ccaagacttg 21960 ttagtcttta tattattagt ttgtctactt gttgactata atgatagtcg ctgataaagt 22020 tgaagtttcc accttaatct ttgttatttt atatccaatt cgccatggtc acattgattt 22080 gattgaattt tcggttgctg gattacaaaa aagaaatgcc aaatgcgata caactgttac 22140 atttagattc agaataggaa attgtttgta taattaaaaa atagaaattg tttattttaa 22200 tacattacta ctgattaatg agtagatgaa tggtggaaga ttgtaaacaa ttatgaagac 22260 aaggtcagca ttgtctttcc gtctagctaa gaagcaaccc gatgtgcaat ttataaagta 22320 gtgcggttta gtgttgatac gttatctttt tgatagtttg attagttatt tcgaaaacac 22380 gttaaaaatg cagtgaattt tgtacagtct tctttacaat ccattcaaca acaattacga 22440 gtacgagcgg ctttatgatg ggtctaacca agatgtaaac ataaccatta ttaagcatat 22500 actacaattc aactgaagaa acaaattcaa tcgaaagggt tgtcgtaatt tctttatatg 22560 gttttcattc aaaaagccta ttgaatgaaa caacttatgt atgataattg cagggtatag 22620 tgatacataa cgaagcttaa tactgctaag tttcttgtca agcatgctac tttctttaga 22680 caattcccaa ttgctttaac taatagctgt tagtgaccaa tttccattgg tttaaggtat 22740 ttttttaaaa aattggtacg attgttgttc ctcctgttag tataaaattt cttggcaaag 22800 cccaaaacct tcaaagttgc gtcttctatt actgtttacc cgccatttcc ttcattattg 22860 ctagtgctct caaatttcaa gccgcttaaa gaataattta aacccttaat aaaactttct 22920 tttaaaacct ccgagtctca actttgatat ttcagctttt tggatgactg ttactgaaat 22980 gtgcgtgtct tttgaaagaa ttctatttat tgacgcgttt tagctttgat aatcagccga 23040 tatgtatcga caatgtatgc cagactcttt ttagccggct atttcctgtt aaactgtcta 23100 gttatattga caaaactatc tagggctctg gatttattaa agctggattc gctggcgatg 23160 atattcccaa atgccttttt ccgacttggt atgaagttta tttctcatac tagatactaa 23220 tatacagtgt tggaagaatt aagcatgagc gtgtcatgcc aagtagtatc caaaaagata 23280 tgtttgttgg ttctgaggct caaaatcttc gcgggttgct taaaattcaa cgtccaattg 23340 aacggggaat catccaaaat tggtccgata tggaagagat ttggagctat atttattcag 23400 atcaacagct caatacttta ccggaagaac atcccttgct tttaaccgaa cctcctttgg 23460 ctaacatccg aaacaaagaa aaaattgcag agtattttta tgaaacgtta aacgttccag 23520 cattgagctt ttccttgcag cctgtattgg cactgtatgc ctccgcacgt acaactggca 23580 ttgttcttga atgtggagat ggcttgactc atagtgttcc tatttatgat gggttttcca 23640 ttccatcagc tatacaacaa gaggaaattg gaggtcgtga cgttacagat tatttgcaat 23700 tgcaacttcg aaaatctggc cacgaactcg tcagctcggc ggagaaagaa attgtccggg 23760 aaattaaaga aaaatgttgc tacgtagcat ctgactttag atcagaaata gaatcatgga 23820 ctgaacacaa accgcagatt catacatatc aactcccaga caaccaaact ataactttgg 23880 gtacagaatg cttttctgcg cctgaggttt tattcaaccc ggaaatgatg ggttctgagg 23940 cgtctggtct tcacatacaa ttgttcaagt ctattttatt gtccgacatc gatttaaggt 24000 caaccttata ttcaaacatt gtactttctg gaggttcaac gttattgaga ggatttgggg 24060 agagattcat ctctgagtta cgtgcaattt ctgggaaaaa aaatcaagtt aaaatttatg 24120 cttcccctga acgtatgcat aatgcttggc ttggcggctc aatattagcc agtctaagta 24180 catttcgtcg gcttttaatt acttcagagg agtataaaaa tgatcaaaac gtaattttta 24240 ggcgaagatt ttgaaactta aaacgagtat tgcagtttat cgctcttcat ttgaaacttt 24300 taaaaccaat attacattgt accagtctaa agctttaaaa tttggtatat cttttaaaca 24360 atcagtctaa tattttcaat tcactaagct atacaaaaga ataccagcag ctactgagac 24420 gtttaatgaa tcaacgtatt tatcaccgcc gggaattgaa acataatgag aacattgcgt 24480 taaaatgttc gttcttaaac cctctttata aagttagcaa taaaggcatt catacaatac 24540 acttactttc acttcctagt acaagtattt tcggttcatt cattagttct gttttgattt 24600 tatgcggggt gtaaatttga tctttgttat ctggcaaagc tggcttggtc cctatgactt 24660 tccaaccttt taaaactgag ttcctcaaaa agaccatagg atttttcacg tggctaatgt 24720 tgaagacttc aagagctcca gctgaagctt tactaacgac cggtgacaag aatgtattat 24780 gtttttttga taataaaatc cctttagcgc ctaaaatata cttaaaccca attagaaatt 24840 ttaaatagta gcaaacgata gcttacagcg cttcgaataa cggcacccat attttgagga 24900 tctgttatac cgtcaacgta aacataaagt ggaggatagt tatcggacga tgagctttta 24960 ccctcattca aatcattatg tggagaatcc tgcccatttt tgttgttgta ctcttcccca 25020 gctgggaaaa gtaaatctga tattgttgga acattcaacg aggatgcctc caaaacaacc 25080 ccctaacatg ttagtgagaa tacaaacaca agtgcatttt cggtgtcttg taaaatcgta 25140 aagggttatg gaccacaaaa attctcagaa aacgtacatt gtgaggtcgg catgctgtga 25200 tttgatttaa atgttcttta ttcacacttt ttattggtat tttgtactgt agtttgttca 25260 aaaattcttc aaattcacta tgaatgtcag cattttgaac ataaagtgct cgacattctc 25320 ttttgcgcgt tgcaagggca ttttttactg aatgcgttcc aaatacgaat tccgaatcct 25380 ctttaattaa ccgccgctcc ttggacaaat gcgctttggc ttttttgggc acctcgcgtg 25440 ctaaattaac acgacttcgt atcattttcg tggttacaaa taagtaaaaa cttactagtg 25500 tcgtttcgta attagcatac actggatatt gtgatgttca aaccaaataa ggattttgta 25560 caaaagtttt agtctaaaaa cacaaaatat tagcaacttt tacatagtaa gcggaaaaag 25620 aattaagtat aaactaaaaa atgagaatta aattggttta aatacaacat aatattatat 25680 gattagacga gaagattgaa taatatttaa aactttaaag aagttaccat catgcaccaa 25740 agaaattaac tgatgtaaaa aagtgtacaa gagattatga catgaagggc aaagaaatat 25800 acaaaatcat tattcgaata gccaatggat atttaaaccg aaatgattaa tatgaaacaa 25860 tatataacct aaaatttaaa aagtatatga atattcttaa atattctagt gcttgttgtg 25920 ttcaggacgg 25930 //