ID   SPBC11C11  standard; DNA; FUN; 22500 BP.
XX
AC   AL031528;
XX
SV   AL031528.1
XX
DT   08-SEP-1998 (Rel. 56, Created)
DT   07-MAR-2002 (Rel. 71, Last updated, Version 4)
XX
DE   S.pombe chromosome II cosmid c11C11.
XX
KW   60s ribosomal protein l5; alp1; FCH domain; Fes/CIP4 homology;
KW   pseudouridine synthase; RNA binding; RNA recognition motif; rpl5-2;
KW   SH3 domain; signal transduction; splicing protein; tRNA-pro; tRNA-Ser;
KW   tubulin-folding cofactor D homolog.
XX
OS   Schizosaccharomyces pombe (fission yeast)
OC   Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes;
OC   Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
XX
RN   [1]
RP   1-22500
RA   Wood V., Rajandream M.A., Barrell B.G., Beck A., Reinhardt R;
RT   ;
RL   Submitted (03-SEP-1998) to the EMBL/GenBank/DDBJ databases.
RL   European Schizosaccharomyces genome sequencing project, Sanger Centre, The
RL   Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail:
RL   barrell@sanger.ac.uk and Max Planck Institut fuer Molekulare Genetik,
RL   Ihnestr. 73, D-14195 Berlin, Germany
XX
DR   GOA; O59720; O59720.
DR   GOA; O59721; O59721.
DR   GOA; O74306; O74306.
DR   GOA; Q10192; Q10192.
DR   GOA; Q10193; Q10193.
DR   GOA; Q10196; Q10196.
DR   GOA; Q10197; Q10197.
DR   GOA; Q10200; Q10200.
DR   SPTREMBL; O59720; O59720.
DR   SPTREMBL; Q9URU5; Q9URU5.
DR   SWISS-PROT; O59721; PUS4_SCHPO.
DR   SWISS-PROT; O74306; RL5B_SCHPO.
DR   SWISS-PROT; Q10192; RL18_SCHPO.
DR   SWISS-PROT; Q10193; SRP1_SCHPO.
DR   SWISS-PROT; Q10195; YBY6_SCHPO.
DR   SWISS-PROT; Q10196; YBY5_SCHPO.
DR   SWISS-PROT; Q10197; ALP1_SCHPO.
DR   SWISS-PROT; Q10198; YBY3_SCHPO.
DR   SWISS-PROT; Q10199; YBY2_SCHPO.
DR   SWISS-PROT; Q10200; YBY1_SCHPO.
XX
CC   Notes:
CC   Details of yeast sequencing at the Sanger Centre are available on
CC   the World Wide Web.
CC   (URL, http://www.sanger.ac.uk/Projects/S_pombe/)
CC   During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced
CC   by the Sanger Centre.  The sequencing of the S. pombe genome is now
CC   being continued with funding from The European Commission.
CC   Fourteen European sequencing laboratories, including the Sanger Centre,
CC   are participating in the project.
CC   Protein coding regions (CDS) have been predicted with the help
CC   of computer analysis using the Genefinder program in PomBase
CC   (an ACEDB database) with additional predictions for the
CC   branch-acceptor sites supplied by the program Sp3splice.
CC   CAUTION: It is possible that for any individual CDS we may have
CC   underestimated or overestimated the number of introns/exons orembl.tab
CC   we may not have chosen the correct splice donor/acceptor sites.
CC   CDS are numbered using the following system eg SPBC25H2.01c.
CC   SP (S. pombe), B (chromosome 2), c25H2 (cosmid name),
CC   .01 (first CDS), c (complementary strand).
CC   The more significant matches with motifs in the PROSITE
CC   database are also included but some of these may be fortuitous.
CC   The length in codons is given for each CDS.
CC   IMPORTANT: This sequence MAY NOT be the entire insert of
CC   the sequenced clone.  It may be shorter because we only
CC   sequence overlapping sections once, or longer, because we
CC   arrange for a small overlap between neighbouring submissions.
CC   Cosmid c11C11 is overlapped by cosmids 17D1 and 3B8.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..22500
FT                   /chromosome="II"
FT                   /db_xref="taxon:4896"
FT                   /organism="Schizosaccharomyces pombe"
FT                   /strain="972h-"
FT                   /clone="cosmid c11C11"
FT                   /map="IIR"
FT   misc_feature    1..1769
FT                   /note="nominal overlap with cosmid SPBC17D1, EM:AL031322 S.
FT                   pombe chromosome 2"
FT   misc_feature    28..40
FT                   /note="ctaatgtgttcag, splice branch and acceptor"
FT   CDS             join(41..739,787..965,1016..1496)
FT                   /db_xref="GOA:Q10200"
FT                   /db_xref="SWISS-PROT:Q10200"
FT                   /note="SPBC11C11.01, len:452, SIMILARITY: LOW to Homo
FT                   sapiens, O15042, kiaa0332, (1028 aa), fasta scores: opt:
FT                   176, E():0.00054, (22.1% identity in 249 aa)"
FT                   /partial
FT                   /gene="SPBC11C11.01"
FT                   /gene="SPBC17D1.08"
FT                   /product="hypothetical protein; contains RRM RNA
FT                   recognition motif; no apparent S. cerevisiae ortholog"
FT                   /protein_id="CAA20683.1"
FT                   /translation="SDDEDDIFLAGERKKYLQNQSYERRKQKYVWSFNNITKSVIRNEH
FT                   GNNLTLQEELLRHEAYEKNEEIANENDVDQGMFIQQNNILNMLVNLMKYFVHMDNISPV
FT                   TTNGSLKESLRKYSSIIAVNIFSETGDLKKGIAIFQDLSDAEQAVQYLSNCKIDGRLIS
FT                   ATITNHPKRLPNAEHLESSTKTKDESQDKDKLTKLDRAKLEWLIQGLNCEKGSIGNLLC
FT                   FAVEHVNNHVEITDAFLKEFFNDQPTDDTKVYDDDYINERGEKKLSLIYLMNDILFNGI
FT                   SGTSLVWRYRFSFEPHVERLLDDLYLFSKRLGGRIKEDIFCKKVVKVIEVWKTWIAFQE
FT                   ETLERAWRNFSGNTPQSPQINSAALKVETKNSWTAISEETEGLQDDEEYNGIPVDVNEL
FT                   LNVEFISQIPMSTETSSSSSPQPTEERKAKFKPSFTQGTFVSKRMRMHAEDLF"
FT   misc_feature    740..745
FT                   /note="gtattt, splice donor sequence"
FT   misc_feature    771..786
FT                   /note="ctaatgtttattgtag, splice branch and acceptor"
FT   misc_feature    966..971
FT                   /note="gtatgg, splice donor sequence"
FT   misc_feature    1001..1015
FT                   /note="ttaattgcgtatcag, splice branch and acceptor"
FT   CDS             join(3189..3257,3352..3443,3509..5181,5230..5408)
FT                   /db_xref="SWISS-PROT:Q10199"
FT                   /note="SPBC11C11.02, len:670,
FT                   SIMILARITY:Schizosaccharomyces pombe, CC15_SCHPO, cell
FT                   division control protein 15.cell division control protein
FT                   15., (927 aa), fasta scores: opt: 647, E():1.2e-27, (26.1%
FT                   identity in 912 aa)"
FT                   /gene="SPBC11C11.02"
FT                   /gene="imp2"
FT                   /product="actin ring component; FCH and SH3 domain protein"
FT                   /protein_id="CAA20684.1"
FT                   /translation="MSQQLSFNASSAKPDKSFSNYFWGANDEGYHALLSRFSDVKHINE
FT                   ELRSFYHERANIEEDYAKRMAKLSRTTFSSLETGCLKESVQVMKAEVDNMAKSHLQISQ
FT                   LLQDDVENAFTRYAASLKDKKKMIVSGIEKVHKDKLSKHQALVKAQDKYHYLCKKVNYY
FT                   VSQQNMLFGKELEKNNAKLNKTQNAITASSSDYQSAVAAVRDSYARWTNEWRSTCDKLQ
FT                   DIEEERRHFLKSVMWTFTLLISRSCFNDDQACERIRKNLEQCSVSQDVLEFIDAKSTGT
FT                   GIPQPPKFYDYYKGEVPDDSVELVQANFQRAQTKIENDNMPLNRPYVLSATARNESSFE
FT                   NTLPNTPSAIQSLTTVSSNSSQNGRSSPKKSFLSKFKLTSRPSTPNVGNTAPDALSSPR
FT                   NDSPLTSAADEQMKHLSLQEEPKQNPTPAAPGAFPNSNTLPPRYNELGSLPSPNSVSFT
FT                   EDSRPNVNTPSRRQQIQEEFGSVLQMENRAVSPVYDSRKNGSRSSFTLRKSRSPKRPSS
FT                   SLSQNASRLPRSLTPGNLEPNYDFGVRVDPASGTAPTDDEPYTDRDSSFVDDTINTKAT
FT                   GNTSNRLSLPAYPTDGGDTSIDNPTSTDGQRILGYVSALYDYDAAIPEEISFRKGDTIA
FT                   VLKLYEDGWWEGFVVGEDDHNRGQFPSNFVREIEV"
FT   misc_feature    3258..3263
FT                   /note="gtatgg, splice donor sequence"
FT   misc_feature    3335..3351
FT                   /note="ctaacattctttattag, splice branch and acceptor"
FT   misc_feature    join(3352..3443,3509..3665)
FT                   /note="Match to FCH ,  Score 94.19"
FT   misc_feature    3444..3449
FT                   /note="gtgaga, splice donor sequence"
FT   misc_feature    3493..3508
FT                   /note="ctaacttcaaccttag, splice branch and acceptor"
FT   misc_feature    5182..5187
FT                   /note="gtatgt, splice donor sequence"
FT   misc_feature    5215..5229
FT                   /note="ctaacttgaatttag, splice branch and acceptor"
FT   misc_feature    5235..5399
FT                   /note="Match to SH3 ,  Score 59.53"
FT   tRNA            5802..5896
FT                   /note="tRNA Ser anticodon GCT, Cove score 39.85"
FT   CDS             join(6056..6083,6133..6316,6360..8022)
FT                   /db_xref="SWISS-PROT:Q10198"
FT                   /note="SPBC11C11.03, len:624, SIMILARITY:Homo sapiens,
FT                   O14777, retinoblastoma-associated protein hec., (642 aa),
FT                   fasta scores: opt: 409, E():2e-15, (22.7% identity in 585
FT                   aa)"
FT                   /gene="SPBC11C11.03"
FT                   /gene="ndc10"
FT                   /gene="tid3"
FT                   /product="centromere-associated spindle component; putative
FT                   spindle pole body; possibly involved in chromosome
FT                   segregation; predicted coiled-coil regions; similar to S.
FT                   cerevisiae NDC80"
FT                   /protein_id="CAA20685.1"
FT                   /translation="MQDSSSYARRYSQAPSSSNLRTTTFGFNGLGTSRTSLAPQRTLVN
FT                   ARQSIDPDGLSSRVLTPTMRPSLAPNTRRSSVRVSNASFISQTPNITSIKDPRPLSDRR
FT                   YQQECATQVVNYLLESGFSQPLGLNNRFMPSTREFAAIFKHLYNKLDPNFRFGARYEED
FT                   VTTCLKALNYPFLDSISRSRLVAIGSPHVWPAILGMLHWVVSLIQCTEKAVAMVYTVEQ
FT                   NSLDDHLVDKVLFDYLVRTYHLYLDESPEESEPEKELKATFNQQNQDLYNQTEALKSTN
FT                   EELINQIKSAEELDSAIQVLEERYRTMQRDEVKFQSAMSGMKSKMESRTNLMKQLQVNI
FT                   EEKESQLQLLKEKRDSLKYQVENQDISISEFEKMVSEREQLDRNLNMIGSKISELRKEV
FT                   FDTDLLIQASIDSLEKKVQKFNSLAYRIGIVPIAAIRSANNDFELEINPEGPNYINLDL
FT                   KNKVRPFINEVRRSITLEFHEEQNKSLKLQEHVDTVNDLIAELQDELRGIESRLTSVLS
FT                   ECNMLRETASEEKNAFDAESDKLERELQQLKLSSHNSMLQLDQRIQSINIEADQIAHAC
FT                   MEYKNNIYKEVAFVLGEIIHFKLHVQDSLEDLKMDYQKELDDLSRSEL"
FT   misc_feature    6084..6089
FT                   /note="gtatgt, splice donor sequence"
FT   misc_feature    6117..6132
FT                   /note="ttaacaataagtttag, splice branch and acceptor"
FT   misc_feature    6317..6322
FT                   /note="gtatga, splice donor sequence"
FT   misc_feature    6343..6359
FT                   /note="ctaatcttgttgcatag, splice branch and acceptor"
FT   CDS             join(complement(11787..11933),complement(10654..11742),
FT                   complement(9623..10609),complement(9201..9583),
FT                   complement(9023..9158),complement(8759..8976),
FT                   complement(8353..8716))
FT                   /db_xref="GOA:Q10197"
FT                   /db_xref="SWISS-PROT:Q10197"
FT                   /note="SPBC11C11.04c, len:1107"
FT                   /gene="SPBC11C11.04c"
FT                   /gene="alp1"
FT                   /product="tubulin-folding cofactor d."
FT                   /protein_id="CAA20686.1"
FT                   /translation="MEEEESLEGIISIDESLITSRLSQILDDVLDDRSSSHSVEKLKDV
FT                   AVKYLQFCQFQPTLLDKLLSKYVPNLASYLLKVKNIGKCNSITVILYQFCKIRGYKAVR
FT                   VLFPVGVQYIKELYTLLNESSNNTWHFHYIVLLWLSQALNTPFPLNSLDDSLDVKKTIY
FT                   TIAIKYLENSGIDKEASCLVLSRLFSRDDGLDLLLGFLHHCESSWFKRSIFYKIGCLFS
FT                   LSSFLKICPRNDCLQTVDVAFQFLNVAREDLVGQENSALRKLLCKCYTRLGIVLLPVNS
FT                   SPNWKYSISNPDSFFQLPDDSNEEVHIYLEVIVDFLLSSVSDIDSFVRWSAAKGLAKII
FT                   SRLPWNLAEQVIDAIIELMTENMFLNPIENTVNISITSPLVWHGAILFFAKLAGAGLIK
FT                   YSKCLHILPLIEVGLSYEVRYGTRVTGQSIRDASCYFVWSFYHCYSKSAIEGLQTNLIL
FT                   CLLQTVLFDNEINVRRAATAALFEVIGRHASIPDGLSLISHINYVSVTDISNCYGDLCM
FT                   KVAHFPQFRSCVFQRLFTNLQHWDVKVQQLSAFSLRQLSIKYPKELSIYLPPILDYLSV
FT                   GNADFIFGYTIGLASIIGGFLSISFPFDINRIHDLLSHKNLLSLKKFSRQQQTKIILGI
FT                   LKGIQQIFANDIRVDRAFFSEAFSVIIAAIDLQEETIIKDISDAYSVLVKFDDMEETLE
FT                   VLLDYIRKCSTSKEARIVYIILQNLPNISFRYQKKICKLLLDIYPQLHSIDYQAPVANA
FT                   LQNIIPFTYEKTESIEEFVKELLQVCSNYLTDTRGDVGSWIRKPAMKAISSLLVKDSSG
FT                   KKLSEDIVWCCISYIIRQTFDKIDSLRGLAYQALEQIRVHYLIRRCEALTNIINRISFR
FT                   NNPNMDGEVLNELNISLLEIPNLRLQAFYGITVFTADGFGSDLAVKCFEFYLSYVYQLE
FT                   DSFKKSNSRYGKRDLLQLYIDILSSEDEIARFYFPIMKSFTSLLAYGCFTDFQNVKGMS
FT                   KAIFIVQRRALTCKSPGGLSAILELYRTLFLSKNELLRHHALKYTANLLLNPIEKVRYQ
FT                   AADTLLYAKSIGLLTFLPNELNQKLLTLDWFVPVSQNATFVKQLRNIIQKQIDKLIADR
FT                   "
FT   misc_feature    complement(8717..8729)
FT                   /note="ctaatgatatcag, splice branch and acceptor"
FT   misc_feature    complement(8753..8758)
FT                   /note="gtatgt, splice donor sequence"
FT   misc_feature    complement(8977..8989)
FT                   /note="ctaactctactag, splice branch and acceptor"
FT   misc_feature    complement(9017..9022)
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    complement(9159..9169)
FT                   /note="ttaaccactag, splice branch and acceptor"
FT   misc_feature    complement(9195..9200)
FT                   /note="gtaaaa, splice donor sequence"
FT   misc_feature    complement(9584..9596)
FT                   /note="ttaacatgaacag, splice branch and acceptor"
FT   misc_feature    complement(9617..9622)
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    complement(10610..10624)
FT                   /note="ctaatccttatttag, splice branch and acceptor"
FT   misc_feature    complement(10648..10653)
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    complement(11743..11758)
FT                   /note="ctaattaaaattctag, splice branch and acceptor"
FT   misc_feature    complement(11781..11786)
FT                   /note="gtatgt, splice donor sequence"
FT   CDS             12987..13841
FT                   /db_xref="GOA:Q10196"
FT                   /db_xref="SWISS-PROT:Q10196"
FT                   /note="SPBC11C11.05, len:284, SIMILARITY:Candida glabrata,
FT                   KRE9_CANGA, cell wall synthesis protein kre9 ., (276 aa),
FT                   fasta scores: opt: 192, E():2.7e-05, (23.8% identity in 260
FT                   aa)"
FT                   /gene="SPBC11C11.05"
FT                   /product="putative cell-wall synthesis protein"
FT                   /protein_id="CAA20687.1"
FT                   /translation="MKTTMLMLVLLVCSYIHYVCAQIRFVTPATTDSMDFTAISFSWEE
FT                   SNTGIPLEDITNTVFYICSGSMDAPQPCAVLYTSPSPSSISQAGPFAISQVFGPAGRLY
FT                   FLWAQSTYAGGIVNDYTDFFTVNGLTGTFDNYEIYASLMALGVYPYVPTLTGFSTFLGV
FT                   WPTGTMRDWYLSQTTGVLRTGPIQNRPDSTFTAATTDIQPLWETSSYSVFTTFAGPPIA
FT                   TSTVFASPTYMYTLYANYASTASKPTIIATPTAGLRRRDSWAQAAPKRGMRLGEHKRGL
FT                   LYS"
FT   CDS             complement(14568..15104)
FT                   /db_xref="SWISS-PROT:Q10195"
FT                   /note="SPBC11C11.06c, len:178"
FT                   /gene="SPBC11C11.06c"
FT                   /product="hypothetical protein; sequence orphan"
FT                   /protein_id="CAA20688.1"
FT                   /translation="MSAKEGSSHPSYAEIVREHAPEQTAAEKAAPQPPEVEEVLSEEPY
FT                   QKNEKVVVLDEEDADAFLHPEEAEAKKESEKPSDGEKKGKTEKLEKEAKSVYSKACNFV
FT                   NAHKVPASAAISINLLSLGAISAYLLKSRQSGTLNNRTLCTCTAIAGIVFTISAVFSKT
FT                   PKTACCASKKSNKST"
FT   tRNA            complement(15727..15798)
FT                   /note="tRNA Pro anticodon TGG, Cove score 57.73"
FT   CDS             16182..16280
FT                   /db_xref="PSEUDO:CAB55861.1"
FT                   /db_xref="SPTREMBL:Q9URU5"
FT                   /note="SPBC11C11.12, similar to part of protein in cob
FT                   intron"
FT                   /pseudo
FT                   /gene="SPBC11C11.12"
FT                   /product="hypothetical protein"
FT   promoter        16939..16947
FT                   /note="Homol E box"
FT   promoter        16960..16967
FT                   /note="Homol D box"
FT   CDS             join(17025..17027,17080..17640)
FT                   /db_xref="GOA:Q10192"
FT                   /db_xref="SWISS-PROT:Q10192"
FT                   /note="SPBC11C11.07, len:187"
FT                   /gene="SPBC11C11.07"
FT                   /gene="rpl18-1"
FT                   /gene="rpl18"
FT                   /product="60S ribosomal protein L18"
FT                   /protein_id="CAA20689.1"
FT                   /translation="MGIDIERHHVKKSQRSKPASENVYLKLLVKLYRFLARRTDSRFNK
FT                   AILKRLFQSKTNRPPISISKIAALTSRKSASSQNKTTVVVGTVTDDERMLTVPKLSIAA
FT                   LRFTKSARARILKAGGEVLTLDQLALRAPTGSNTVLVRGKKHAREAYRHFGFGPHKHKA
FT                   PYVRSEGRKFERARGRRKSRAFKV"
FT   misc_feature    17028..17033
FT                   /note="gtatgt, splice donor sequence"
FT   misc_feature    17064..17079
FT                   /note="ctaatgagtgatttag, splice branch and acceptor"
FT   misc_feature    17107..17637
FT                   /note="Match to Ribosomal_L18e ,  Score 465.94"
FT   CDS             join(18092..18177,18224..18280,18330..19014)
FT                   /db_xref="GOA:Q10193"
FT                   /db_xref="SWISS-PROT:Q10193"
FT                   /note="SPBC11C11.08, len:275"
FT                   /gene="srp1"
FT                   /gene="SPBC11C11.08"
FT                   /product="pre-mRNA splicing factor; RNA-binding protein; no
FT                   apparent S. cerevisiae ortholog"
FT                   /protein_id="CAA20690.1"
FT                   /translation="MSRRSLRTLYVTGFRDGMRARELAYEFEPFGPLIRCDIPIPRTRT
FT                   SRPFAFVEYEDSRDAEDAYYEVHGRRLERGGGVLRVEWAKQPPPSGPGSKRGGRRERGG
FT                   RVHGDSGRLRSRSPSPHEARSRSPYNDERSDRRSMSPRYRSRSRSPDGRSRSPDYDRRS
FT                   PKRNHRSPSPVSFAPQKSPVENETETNVDNGDTKISESNEKSGTEVEQQSAPNSNGNEE
FT                   VNNLEPVGQNESKQEPPKEENSNVSQEQPEQAQPEVSAASEQPESNPTTTESQ"
FT   misc_feature    18116..18334
FT                   /note="Pfam match to entry PF00076 rrm, RNA recognition mot
FT                   if. (aka RRM, RBD, or RNP domain)"
FT   misc_feature    join(18116..18177,18224..18280,18330..18405)
FT                   /note="Match to rrm ,  Score 21.75"
FT   misc_feature    18178..18183
FT                   /note="gtaagt, splice donor sequence"
FT   intron          18178..18223
FT                   /note="confirmed by mRNA"
FT   misc_feature    18207..18223
FT                   /note="ctaatttattcatttag, splice branch and acceptor"
FT   misc_feature    18281..18286
FT                   /note="gtaagt, splice donor sequence"
FT   intron          18281..18329
FT                   /note="confirmed by mRNA"
FT   misc_feature    18310..18329
FT                   /note="ttaaccgtcttattggatag, splice branch and acceptor"
FT   CDS             complement(19954..20838)
FT                   /db_xref="GOA:O74306"
FT                   /db_xref="SWISS-PROT:O74306"
FT                   /note="SPBC11C11.09c, len:294"
FT                   /gene="rpl5-2"
FT                   /gene="SPBC11C11.09c"
FT                   /gene="rpl5b"
FT                   /product="60S ribosomal protein L5"
FT                   /protein_id="CAA20691.1"
FT                   /translation="MPFIKAVKSSPYFSRYQTKYRRRREGKTDYYARKRLIAQAKNKYN
FT                   APKYRLVVRFSNRFVTCQIVSSRVNGDYVLAHAHSSELPRYGIKWGLANWTAAYATGLL
FT                   VARRALAKVGLADKYEGVTEPEGEFELTEAIEDGPRPFKVFLDVGLKRTSTGSRVFGAM
FT                   KGASDGGLFIPHSPNRFPGFDIETEELDDETLRKYIYGGHVAEYMEMLIDDDEERYQKQ
FT                   FSGLIADGIESDQLEDIYAEAYAKIREDPSFQKSGKDAAAFKAESLKYTQRKLTAEERK
FT                   ERFNAKVIEAGRA"
FT   misc_feature    complement(20320..20763)
FT                   /note="Match to Ribosomal_L18p ,  Score 269.35"
FT   CDS             join(20898..21102,21206..22224)
FT                   /db_xref="GOA:O59721"
FT                   /db_xref="SWISS-PROT:O59721"
FT                   /note="SPBC11C11.10, len:407, SIMILARITY:Saccharomyces
FT                   cerevisiae, PUS4_YEAST, pseudouridylate synthase 4, (403
FT                   aa), fasta scores: opt: 436, E():1.2e-20, (32.9% identity
FT                   in 359 aa)"
FT                   /gene="SPBC11C11.10"
FT                   /gene="SPBC3B8.13c"
FT                   /product="putative pseudouridine synthase"
FT                   /EC_number="4.2.1.70"
FT                   /protein_id="CAA20692.1"
FT                   /translation="MTVTNTYNPTLFFTRVVFQRITKFTAKANEENEILFYALFVADLC
FT                   LDMKGGLIAINKPSGRTSAQCLNELKKIISNSELAQYFRPAPPHPNDRNRRRRKSNRLP
FT                   DIKIGHGGTLDPLASGVLVVGLGTGTKQLSSLLSCMKTYRATALFGCSTDTYDSAGKII
FT                   KIAVHIPTKEEILSGLDAFRGDISQLPPLYSALHIQGKRLYEYAREGIPLPESIKARSM
FT                   HCEELILKDFIPKEEHTYTDPDEFASKEAIESEELLRPIEGGAERHDLLAKTEQDINPQ
FT                   DGDEKINAKSPTTNSVTDVAKDQTVTNPKKRKFEVTDLARGSRPAIGPIAVLDMTVSSG
FT                   FYVRSLIHDLGRQVNSEAHMVDLVRLKQGSFALDDENCFDFSEFSAPGWEEKLAAAFKI
FT                   DLKGDETS"
FT   misc_feature    21103..21108
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    complement(21191..22500)
FT                   /note="nominal overlap with comsid SPBC3B8, EM:AL022244
FT                   S.pombe chromosome 2"
FT   misc_feature    21195..21205
FT                   /note="ctaactgacag, splice branch and acceptor"
FT   misc_feature    21289..21753
FT                   /note="Match to TruB_N ,  Score 263.97"
FT   CDS             complement(22379..22500)
FT                   /codon_start=3
FT                   /db_xref="GOA:O59720"
FT                   /db_xref="SPTREMBL:O59720"
FT                   /note="SPBC11C11.11c, len:39"
FT                   /partial
FT                   /gene="SPBC11C11.11c"
FT                   /gene="SPBC3B8.12"
FT                   /product="DEAD/DEAH box helicase"
FT                   /protein_id="CAA20693.1"
FT                   /translation="ITKVIYGGKGRQVRTDKLQSYLKHDANLKRITTLKELKG"
XX
SQ   Sequence 22500 BP; 7224 A; 4082 C; 3994 G; 7200 T; 0 other;
     gatcagtttt aaataaccta atcaagtcta atgtgttcag agtgacgacg aagatgatat        60
     ttttctcgca ggcgaacgta aaaaatatct tcaaaatcaa tcttacgaaa ggaggaagca       120
     aaagtacgta tggtctttta ataacattac taagtctgtc attagaaatg aacacggaaa       180
     caatttgact cttcaggagg aactattaag acatgaagca tatgaaaaaa atgaagagat       240
     agctaatgaa aatgatgttg atcaaggtat gttcattcaa cagaataaca ttctaaatat       300
     gttagtcaat ctaatgaaat attttgtaca catggacaat atttcacccg tgactacgaa       360
     cggttccctt aaagaatccc ttcgaaagta ttcatcaatt attgctgtga atattttttc       420
     tgaaaccgga gacttgaaaa aagggattgc tatttttcaa gatctttcag atgccgaaca       480
     agccgtacag tatttgtcta attgtaaaat tgacggtcga cttatttcag ctacaatcac       540
     gaatcatcca aaacggttgc ctaacgcaga gcacctagag tcttcaacga agacaaagga       600
     tgaatctcag gataaagata aattgacaaa acttgacagg gcaaaattgg agtggttgat       660
     acagggattg aattgtgaaa aaggaagtat tggaaatcta ctctgctttg ctgtagaaca       720
     tgtcaataac catgtagagg tatttttgtt tcaagactat attcgtcatg ctaatgttta       780
     ttgtagatta ctgatgcatt tttgaaagag ttttttaacg atcagcctac tgatgataca       840
     aaagtttacg acgatgacta cataaatgaa agaggtgaaa agaaattgag tttgatatat       900
     ttaatgaacg acattctatt taacggcata tcaggtactt cattagtttg gcggtaccga       960
     tttaggtatg gttttaaaac ttttactatt gaattgaaaa ttaattgcgt atcagttttg      1020
     aacctcatgt tgaaagatta cttgatgatt tatatctttt cagcaagcga ctaggaggaa      1080
     gaataaaaga agatattttt tgtaaaaaag tagttaaggt tatagaagtt tggaagacct      1140
     ggattgcttt tcaggaagaa acactggagc gtgcatggag aaatttttcg ggaaataccc      1200
     ctcaatcacc acaaataaat tctgctgctt tgaaagtgga aacaaagaat agctggacag      1260
     caatttctga agagactgaa ggacttcaag atgacgaaga gtataatggt attcctgtcg      1320
     atgtaaacga attgttaaac gtagaattca tatcgcaaat accaatgagt acggaaacaa      1380
     gctccagttc aagcccgcag cctacggagg aacggaaagc aaagttcaaa cccagtttta      1440
     ctcaaggcac attcgtctca aagcgcatgc gtatgcatgc ggaggattta ttctagaaaa      1500
     tagaagaatg caattgataa aaaagaacta cacttctaca atttagaata tcgcttttca      1560
     tataaacaag gtatgactga tgttaaattt atccattttt aactacccgt aatactatta      1620
     tactttaatg acaacgattt ttgttttctc tttcatcaag cattgtattg aataacttat      1680
     agacgaagaa tgctattgct gctgtgcaaa ctggctttat caattcgata tataaacagt      1740
     tttcgccatg catggctaag atcgtaaagt tcagcatcac aaaaagttgg aggatcatgt      1800
     tttaaaagtg agtataagta cttgtaattt tagacactac attttagcag gggcttcatc      1860
     ggctttcgcc tcagcacttc tcttggagtc ggcagtatcg ctttccgact ttactgcttt      1920
     tccaacgtca tcaaaaaagt tgttaattcc atgtcgcaca cgttcaatac cataaacaat      1980
     cttgtggtcg gctttacgaa cgtcttcttt accttcgcgt tccattattt ataatttcag      2040
     aggatgtaca aaaaattcaa ggttggtcgt attatcaaaa cttcgcaaat gtatagggac      2100
     aaaagcaatt aataacttta atctcaccta gtgtttaagt gtgatagaat gagtatttat      2160
     caccagttgt tttgttaaag aataaaccgc cgaagccggg cggctgctgt atatatagta      2220
     aacatatcag cgtccctacc gccaacccat gacgtaagtc gggttattaa gaaatgcgat      2280
     ctcgtgaaat aaaaaataag attgaaaata atggaaattg gaagaaaaac cgagaattac      2340
     aagggcgttt tgtatgtacc tgataaatga atatgtttaa tctatttgac tcacataaac      2400
     gttgtattta tgtttttttt agtgtttatt tattttttcg attagtgtat ttcactaagt      2460
     aaacaaatta ttatacgatt ttttattcac atcgaatgat gctgcaggta caaatcgagc      2520
     tatctaaaaa atattacttt tcagtacgcc tgaaccgctt gcatagtata ttaagttttt      2580
     gattaatagc atgttgcatt ccattcaaaa atttaatatt ttacatagta aaacgatttg      2640
     agacgggaga tagctataca gaacgtgaag tctgcaaata catacatgct aaatcattgt      2700
     tttattagca taatgtctaa gtctataagt tcgcttaccg gagtttatgg taagtatttt      2760
     ttttcaggac tgccttgggt cgcttctcaa atcacagtat tcacacataa tcaatacaaa      2820
     atagtgagca aaacttgtgc gcttaacaga gataacaatt atagagtctc aaggatgaat      2880
     aaagtggact ttgaatgaat caattgttca ccatatatat ctcagcattt gaaggctttt      2940
     tatctttcca ctgcaatatt ctattgcttt tttttgatag tttaaggctg aaaaatcttc      3000
     attacatcgg ttttcttgat aaatttgtta attgttgaca tgaaaagctg cacctggcaa      3060
     cgcgttgccg tttgtttacc tcgttgttag tttcatttac aatcaacacc accaccatat      3120
     acgaataaag aatactgcca taaaggcgag attgaaaaat ctcttaattc gtgttttttt      3180
     ccgtttacat gtctcaacaa ttaagcttta atgcatcttc agcaaagcct gataaaagtt      3240
     tttcaaatta cttttgggta tggtgtctaa gccaacgtgg atagctcatt atctgccaaa      3300
     actttcgatt tttgtgttaa acacaacacc ttaactaaca ttctttatta gggtgcaaat      3360
     gatgagggtt atcatgcttt actttcgcgt tttagcgatg tgaaacacat taatgaagag      3420
     cttcggtcgt tttatcatga aaggtgagaa atttgaggtg aagcagggtt taacatgcta      3480
     tgatcgttta ttctaacttc aaccttagag cgaacattga agaagattat gccaagcgaa      3540
     tggcaaagtt gtctcgaaca accttcagtt ctttggaaac tggttgcctc aaagaatcag      3600
     tccaagttat gaaagctgaa gttgacaata tggcaaagtc tcatttgcag atttctcagt      3660
     tgcttcagga tgatgtcgaa aatgcgttta cgcggtacgc tgcctcttta aaggacaaga      3720
     aaaagatgat cgtttcgggg atagaaaaag ttcataagga taaactctcc aagcatcaag      3780
     ctcttgttaa agctcaagac aaataccatt acttgtgcaa gaaagtaaat tactatgttt      3840
     ctcagcaaaa catgcttttc ggaaaggagc tagagaagaa caatgcgaaa ttaaacaaga      3900
     ctcagaatgc tatcactgct agttcttctg actatcaatc agctgtagca gctgtcagag      3960
     attcatacgc tcgttggacc aacgaatggc ggtcaacctg tgacaaactt caggacattg      4020
     aagaagaaag aagacatttc ctgaaaagcg tcatgtggac atttacacta cttatctctc      4080
     gtagttgctt taatgatgat caagcatgtg aacgaattcg caaaaatctt gaacagtgca      4140
     gtgtctctca ggatgttttg gaatttattg acgcaaaatc tacaggaacg ggaattcctc      4200
     aacctccaaa attttatgac tattataagg gcgaggttcc cgatgattct gtagagttgg      4260
     ttcaggctaa ttttcagcgg gcccaaacca aaatagaaaa tgacaacatg ccattgaatc      4320
     gtccatacgt cctttctgcc accgctcgta atgagtcgtc cttcgaaaat acccttccta      4380
     atactcctag tgcaattcaa tcgcttacca ctgtttcttc taactcttcc caaaatggta      4440
     gaagctctcc aaagaaaagc tttttgagta agtttaaatt aacgagtcgt ccttcgactc      4500
     caaacgttgg taatacggct ccggatgcat tatcaagtcc gagaaatgac tctcctttaa      4560
     cttcagcggc tgatgaacag atgaagcatc tttctttaca agaagagcca aaacagaatc      4620
     ctacgcctgc tgctcctggt gccttcccta actctaatac actaccacca aggtataacg      4680
     aacttggttc tctaccaagt cctaattctg tttctttcac cgaggactcc cgcccaaatg      4740
     ttaacactcc atcacggcgt caacaaattc aggaagaatt tggtagtgta ctacaaatgg      4800
     agaatcgtgc ggtttcaccc gtttatgatt caagaaagaa tggatctcga agttcattca      4860
     cattgaggaa aagtaggtca ccaaaacgtc cttcctcttc cctttctcag aatgccagcc      4920
     gacttcctcg ttccttaaca ccaggaaatt tagagccaaa ttatgatttc ggtgttcgag      4980
     ttgatccagc aagtggtact gcacctaccg atgacgagcc ttatactgat cgggactctt      5040
     cctttgttga tgatacaata aatacaaaag ctactggaaa cacgtctaac cgactttctt      5100
     tacctgcata tcctacagac ggcggtgaca ccagtattga taatccaaca agtacagatg      5160
     gtcaacgtat tcttggttat ggtatgtcta atctgtccat cgctattaca attactaact      5220
     tgaatttagt atctgcttta tatgattatg atgctgcaat acccgaagag ataagcttca      5280
     ggaagggaga taccattgca gttcttaagc tttatgaaga cggctggtgg gagggatttg      5340
     tcgttggaga ggatgaccat aaccgtgggc aatttccgtc aaattttgtt cgtgaaatcg      5400
     aggtttagct ttcgtattat agtttcgcat tttctcatct tttctcattc tcatttaaat      5460
     ctaaaatact agatttctaa ttttggttgt tttacattat aggatattta gaatgctaca      5520
     cgtttagtta agttatctac attataagat tattatctta taaatcttta tgaattttgc      5580
     agattaaaat gataccgatt gttatatata gcattatgtt caaaatgatt gaattattgt      5640
     cattcattgc accattttct acctaaatat ttctagtaat tctcgtttgc ttctaaaatt      5700
     ctgtaataac ttaaaaaaca tcaaatcttt accaatctaa gttaacacac aggtctataa      5760
     tagcttcatg tataactaat tactatttcc tagtaagctg tgacaacgtg gccgagtggt      5820
     tttaaggcgt tcgcctgcta ttctgtagcc cagcggattc cctttgggag cgcaggttcg      5880
     aatcctgccg ttgtcgatat cttttttaag ttgcaaagcg attcactata aatttttgcg      5940
     gttctatatt ggaaatcgct attcactgtt atttttgtta cttagcaaag tggttttgtt      6000
     gttataacta acgtctccaa cgataaaaga caacaatctg cttgtattac tataaatgca      6060
     agattcttcc tcttacgcga ggcgtatgtt ttcttttttt tcttttgact aataagttaa      6120
     caataagttt agggtattca caggcacctt cttcatctaa tctacgaact actacttttg      6180
     gattcaatgg actgggtact tcaagaacca gtttagcacc tcaaaggact cttgtcaatg      6240
     cacgacagtc cattgatcct gacggtttgt cttctcgtgt gttaacccct acaatgcgcc      6300
     caagtttggc tcctaagtat gataatattt actgaatttg ttctaatctt gttgcatagt      6360
     acccgtcgct ccagcgtgcg cgtttccaat gcatctttta tttcccaaac acctaatatt      6420
     acttctataa aagatccaag accattgtca gacagaagat accaacaaga atgcgctacg      6480
     caagtcgtca actatttatt agaatctgga ttttcacagc cattgggttt aaataatcgt      6540
     ttcatgccat caacgagaga gtttgctgcc atcttcaaac atttgtataa taagttggac      6600
     ccaaatttta gatttggcgc acgctatgaa gaagacgtta ctacttgttt aaaagcactc      6660
     aattatccgt tccttgattc catctcacgc tctaggcttg tcgctatagg ctctcctcat      6720
     gtatggcctg ctatattggg tatgcttcac tgggttgttt cactaattca atgcactgaa      6780
     aaggcagttg ctatggttta taccgtagaa caaaatagcc ttgacgatca tctcgtggac      6840
     aaagttttgt ttgactacct tgttcgcaca tatcatttgt accttgatga atcacccgaa      6900
     gaaagtgaac cagagaaaga attaaaggct acttttaatc aacagaacca ggatttgtac      6960
     aatcagacag aagctttaaa aagtacgaat gaagaattga ttaatcaaat aaaatctgct      7020
     gaggaactgg actctgcaat ccaggtgctt gaagagcgct atcgaactat gcaacgtgat      7080
     gaagttaagt ttcagtctgc gatgagtgga atgaaatcaa aaatggaatc caggactaac      7140
     cttatgaaac aactgcaggt aaatattgaa gaaaaagagt ctcagctaca gcttttaaaa      7200
     gaaaaaaggg actctctgaa gtatcaagtt gaaaatcaag atatttctat aagcgaattc      7260
     gaaaagatgg tctcagagag ggagcaatta gacagaaatt taaacatgat tggaagcaag      7320
     attagtgaat taaggaaaga agtgtttgac acggacttgc tcattcaagc tagcatcgat      7380
     tctttagaaa agaaggtaca aaaattcaac tccttggctt acagaattgg aattgtaccc      7440
     attgccgcta ttcggtctgc caataacgat ttcgaactcg aaattaatcc agaaggccca      7500
     aattatataa atttggacct gaagaataaa gtacgcccat ttattaatga agttagacgt      7560
     tctattacac ttgagtttca tgaagaacaa aataaatccc taaagttaca agaacatgtt      7620
     gataccgtta atgatttgat agctgaatta caagacgagc taagaggtat agaatctcgt      7680
     ttaacttcag tattgtcaga atgtaatatg cttcgtgaaa cggccagtga agaaaaaaat      7740
     gcatttgatg ctgaatcgga taagttagaa agagaattac aacagctcaa actttcttcg      7800
     cataacagca tgcttcaatt agaccagcgt atacaaagta taaatatcga agcggatcaa      7860
     attgcacatg cttgcatgga gtacaaaaac aatatatata aagaggttgc atttgtgctt      7920
     ggtgaaataa tacatttcaa gctacacgtt caagacagtt tggaggattt gaagatggac      7980
     taccaaaagg aattggatga cctatctcgt tcggaactgt aaattctatt catcgtattg      8040
     tgctgtctac tatattcacg gctcatgaat acattttttt atcacgatgg tgtttttgtg      8100
     ttttatgctt taatctctta ctttttaatt acaattctaa tgaaggtaat aataattcaa      8160
     ctctcaattt tcaaatgtaa tttttattgg ttgtgttcct tttatggaca tcaatttagt      8220
     actacataag cacgaactgt tttggctaaa aatttgagat tattcaccag atattttatt      8280
     gattgcagat tttaacgttt ttatacatca tatacacgac tatttaaaaa gctgaaagta      8340
     gttcaaaatt tattatcgat cagctatcag tttatctatt tgtttctgta ttatattcct      8400
     tagctgttta acaaaagttg cgttttgaga tactggtacg aaccaatcca aagtcagtag      8460
     tttttggttt aattcattag ggaggaaagt tagcaaacca attgacttcg catagagcaa      8520
     agtgtcggct gcttggtagc gtactttttc aatcgggttt aatagtaggt ttgccgtata      8580
     ttttaaagca tgatgcctca aaagttcatt tttggaaaga aaaagcgtcc gatataactc      8640
     tagtatcgca gaaagtcccc ctggtgattt acaagtaaga gcccttctct gtacaataaa      8700
     aatcgctttt gacatgctga tatcattagt attttgaaca aaatgtaaaa aaacataccc      8760
     cttaacgttt tgaaagtccg tgaaacaacc atatgctaac aaagatgtga aagatttcat      8820
     gattggaaaa tagaaacgag ctatttcatc ctccgaagaa agtatgtcta tatagagttg      8880
     tagaagatcc cgtttaccat aacgagagtt agatttttta aacgaatctt ctaactggta      8940
     aacataactt agataaaatt caaaacattt aactgcctag tagagttagt atattaagac      9000
     atcgaagcat atgataactt actaagtcac tgccaaaacc atcggcagta aatactgtaa      9060
     ttccgtaaaa agcttgaagc cttaaattag gtatttctag cagagatata ttcagttcat      9120
     ttagtacctc tccatccata tttggattat tcctgaaact agtggttaat agcagaattt      9180
     taattgaaaa ctcattttac ctaatacgat taataatatt agtcaaagct tcgcatcttc      9240
     tgattaggta atgtactctg atttgttcga gtgcttgata tgccaaaccc ctcaaactat      9300
     caattttatc aaatgtttgc cttataatat aggaaataca acaccaaact atatcttcac      9360
     ttaatttttt tccagatgaa tctttgacta atagactgga aatggccttc attgcaggtt      9420
     tgcgaatcca tgagccaaca tctcctcggg tatctgtcaa ataattggag caaacctgaa      9480
     gtaattcttt gacaaattct tcaatgcttt ctgttttttc ataagtaaag ggaataatat      9540
     tttgaagcgc attcgcaaca ggtgcttgat agtctattga gtgctgttca tgttaacatt      9600
     ggtgaaaaaa ttctttactt acgagttggg gataaatatc caataaaagc ttgcatatct      9660
     ttttctggta tcgaaaactt atattcggta aattctgtag aataatgtat acaattctcg      9720
     cttctttact tgttgagcat tttcgtatat agtcaagaag aacctccaat gtttcttcca      9780
     tatcatcaaa tttaacaagt acactgtaag cgtcactgat gtcttttatg attgtttcct      9840
     cctgtaaatc aatagcagcg attataacag aaaatgcttc actgaaaaat gctctgtcaa      9900
     cacgaatatc attggcaaaa atttgttgaa ttccttttaa aattcccaaa ataatttttg      9960
     tttgctgttg ccttgaaaat ttttttaagg acagtaggtt tttgtgcgac agtaaatcat     10020
     ggatacgatt tatatcgaac gggaagctta tggataaaaa tccacctata atacttgcca     10080
     atccaatcgt atagccaaaa ataaaatctg cattaccaac agacaaataa tcaagtatgg     10140
     gaggaagata gatgcttagc tctttgggat atttaataga aagttgtctt agggaaaaag     10200
     cagaaagctg ctgtaccttc acgtcccagt gctgaaggtt tgtaaatagt ctttggaaaa     10260
     cacaggaacg aaactgagga aaatgagcta ctttcataca caagtcacca taacaatttg     10320
     aaatatccgt tacagaaaca tagttaatat gtgatatcaa agaaagccca tcgggaatag     10380
     aagcgtgtct gccaatcacc tcaaataaag cagcagttgc agctctgcgc acatttattt     10440
     cattgtcaaa caataccgtt tgtaagagac ataaaataag attcgtttgt aagccttcaa     10500
     ttgctgactt agagtagcaa tgataaaatg accaaacaaa ataacaggag gcatctctga     10560
     tgctttgtcc tgttactcta gttccatatc ttacttcgta tgataagccc taaataagga     10620
     ttagaatgat ataagaaaac aaagtgtact tactacttcg atcaatggaa gaatatgtaa     10680
     acatttacta tacttaatta aacctgcacc tgctagtttt gcgaagaaaa gtatagctcc     10740
     gtgccaaacc agtggagaag taattgatat gtttacagtg ttttctatgg ggtttaaaaa     10800
     catattttct gtcatcaatt caataatggc atcgataact tgctcagcca aattccaggg     10860
     caaacgactt atgatcttgg ctagcccttt ggctgcagac cagcgtacaa aactgtctat     10920
     gtcgcttaca gatgacaata aaaaatcaac aataacctcc agatatatat gtacttcttc     10980
     gttagagtca tcaggtaatt gaaagaaact atctgggtta ctgatcgagt atttccaatt     11040
     aggggatgaa tttacaggca gcaatacaat tcccaatctt gtataacatt tgcataataa     11100
     tttcctcaac gctgaatttt cttgtccaac taaatcttct cgtgctacat tcagaaactg     11160
     aaacgcaaca tcaactgttt gaagacaatc atttctcgga caaattttaa gaaaagaaga     11220
     taaggaaaaa agacacccaa ttttgtaaaa gatacttctc ttaaaccaac tactctcaca     11280
     gtggtgtaga aagcctagaa gtaaatccaa accgtcatca cgagagaata atcgggacaa     11340
     aacaagacaa gaagcttctt tgtctattcc cgaattttct aagtatttaa ttgctatagt     11400
     gtaaatggtc ttcttcacat ccaaggaatc atctaatgaa tttaacggga atggggtatt     11460
     gagtgcttga gaaagccaca gtaaaactat gtagtgaaaa tgccaggtat tatttgatga     11520
     ttcatttaat aatgtatata attccttaat atattgaacg ccaacaggaa agaggacgcg     11580
     aacagcttta tatcctctta ttttacaaaa ctggtaaagg ataacggtaa ttgagttaca     11640
     ttttccgata tttttcactt tcagtaaata gctagccaag tttggaacgt atttactcag     11700
     tagtttatcg agcaatgtcg gctgaaattg acaaaattgc aactagaatt ttaattagaa     11760
     aggtcacaat atctttttaa acatacatat ttaacagcga cgtctttaag tttttccaca     11820
     gaatgtgaag aacttctatc gtctaaaaca tcatcgagaa tttgcgataa acgtgaggtt     11880
     atcaaagact catctataga aataattcct tctaaagatt cttcttcttc catttttgtt     11940
     taaaatttat gctatgatta tttttgactg taacgacttt aagcaattaa cgcgtgttga     12000
     ataaattatg aaaaacgaat aaagcgaaaa aatatgttaa tctcctttct tttagaattt     12060
     ctttcgtcct aaaaaaaaaa cttggtccct aattttctgt attgccttgg acaatttcct     12120
     cctttgtcac tcatgaggtt gcaaatgata ccaataagaa aataaaacaa gtttgaataa     12180
     ttttagacct gtaagattta ttaacgatta aatttcacaa gctttgatat tgaaaaacat     12240
     tatgaaaagt gggataataa aaaggtaaat tattgtggtg gtgtaatctg tacccactac     12300
     tgatatttca aatctcaaat ctaaacgtga gcagttatta agaatgcttt tggagcaacc     12360
     actgtgatat ttgtaaatga tatattattt ctgcgaatga attaggaata cagccagaca     12420
     gtaagcatat ctggtagtaa agggcctata tattgacagc tctaacgcaa ttatttcata     12480
     gagtagacat aatattcacg acatagattc agtaagttcg catgttattc attcttttgg     12540
     tacaagacta gcatttgata ttacaaatgt atagcagtat cgtttaaata gatctttact     12600
     taaagattct caaacgttac aataattttc ccaagatgtt ggcctttaaa ctagtcggca     12660
     taaatttaca gagcaattgt aagtacttgc taaactgaag agaatttgaa ttagaggttt     12720
     caggttaaaa catattcagt gttaactata tccagcttgt tcgtgatata tatttttgag     12780
     ttaagccgaa atttattgca tgaaataaaa aataaaaaaa aataaaaaaa tcacttttat     12840
     tagcttacaa taaaccaact tttctcgatt atttgtttac acatgtcaaa taaggtgttt     12900
     cgatatacat ccctgttgtc agagcaacga tttatatata tcgcttacca ctaaatttgc     12960
     aaagtctctt caagccgtcg aatttaatga aaaccaccat gttgatgcta gtattgctag     13020
     tctgctcata catacattat gtatgtgcgc aaattcgatt cgtcactccg gcgacaacag     13080
     atagtatgga ttttaccgct atttcgtttt catgggaaga atctaatacg ggaatacctc     13140
     ttgaggacat aaccaacaca gttttttata tatgtagtgg tagcatggat gctcctcaac     13200
     cttgtgcagt cttgtatacg tcccctagtc cttcttctat atcccaagct ggacccttcg     13260
     ctatttctca ggtttttgga ccagctggac gtctttactt tctttgggca caatctacat     13320
     atgctggtgg tatagttaat gactatactg actttttcac tgttaatggt ctaacaggaa     13380
     cttttgataa ttacgaaatt tatgcgtctt tgatggctct tggtgtgtat ccttatgttc     13440
     ctacccttac tggttttagc acttttcttg gtgtatggcc tacaggtaca atgcgagatt     13500
     ggtatctatc tcaaactacc ggtgttctcc gtacaggacc tattcaaaat cgaccagatt     13560
     ctacttttac tgctgctacg accgacatac aaccgctatg ggaaacttcc tcttattccg     13620
     tatttaccac gtttgcaggt cctcccattg ccacctcgac tgtctttgca tctccaacgt     13680
     acatgtatac gttgtatgct aattatgcta gtacggcctc taagcctact ataatcgcaa     13740
     ctccaactgc tggtttaagg agacgagaca gctgggctca agctgctccg aaacgtggga     13800
     tgcgtttagg tgaacacaaa cgtgggttgt tatattccta aattgttaat tttttttaag     13860
     gccaaagcct ttcatgtcat ttagattttt cattagcaca ctaggatatt actgtgtgca     13920
     tttttgtctg cttcctttag ctcaaataca ttgagtcgtt cgtcaaagaa aacaaaatat     13980
     tttggttatt tgttatctaa agtcatgttt tttttcatat ttaccattat gctgtttctg     14040
     tggagttaat ttcacgtaaa agcatcttca agtgcatgag ttatttcttc attcgttcaa     14100
     tttttacttt cctttctccc ttttcattcg ttcttttaca tatttaggca aaaagaactc     14160
     tcggttaaac ccttttcttt agttatcatt ttctacattt aataaataat tatggtttta     14220
     tttagaattt attttgtaaa ttatacttgt ttgaacgcat tgtttaatta agtaatcgcg     14280
     acaaataaat aaattgtgtg atgacagtgc tatgccagaa cgcccaaata gtcggaatca     14340
     attactaaat tcactaagtt aatattgcaa aagcattaca agtaatgttc aattaaatca     14400
     taacattaaa taaaatattg tgatatacta tagaggtatt cttcatcaaa cctgtaaaat     14460
     gcagcagaag tgcagaaaat caagagggga tatgttaatt taagaagatg ataggaataa     14520
     acaatactgg agattttcaa acaatgaatt ccagatttta acgaacatta agttgattta     14580
     ttagactttt tggaagcaca gcatgcagtt ttgggagtct ttgaaaatac agcgctgatt     14640
     gtaaatacaa tgccagcaat agcggtacag gtgcaaagag tacgattgtt aagggttcca     14700
     gattgacggc ttttcaagag atatgcagag atggcgccaa gactgaggag gttgattgat     14760
     atggcagcag aagctggaac tttatgagca ttgacaaaat tgcaagcttt ggagtaaaca     14820
     gatttcgctt ctttttccaa tttctcagtt ttacctttct tttccccatc ggatggtttt     14880
     tctgattcct tctttgcctc cgcctcttcg ggatgtagaa aggcgtcggc atcttcctca     14940
     tctaaaacga caactttttc atttttttgg tagggttctt cactcagaac ttcctcaact     15000
     tcaggaggct gtggtgcggc tttttctgct gctgtttgtt caggagcatg ttctcttaca     15060
     atctcggcat atgagggatg ggagcttcct tcttttgcag acatcttaaa aaatttttca     15120
     gtgaatatga ggagagataa aagtcaaatt ttcttcaaag ttgtaaacac taacgaattt     15180
     gatttaaatt ggtatgttgt ggtgggtata tatgtattaa tagaatttac atactttgcg     15240
     tatacagtat gacgtcctca gttgacatca taatagttta agcactgtac tgaagatact     15300
     catcatctat agtagattcc agcaagttag cgtagaaatc cgtttactaa gtggcattac     15360
     gattctttat cgctgtttaa ggtgatacaa tattttatta tggtgaacag aaaatgaatt     15420
     actttttcct ttttaaatat agtgttatga atgatttaat atttaatgac caaaaaatga     15480
     tagcctatta ctacttgcat gttaaagtgt ttcaaaaagg acagctttaa ccatattcgc     15540
     taaagaaaac taaagaggtt tattataagc acaaactata gtgaacagaa agtatttacg     15600
     gcatttgtga taatatttgc taaatggccg cgtgtttact acccgcagtc aggaatggca     15660
     gaaaacataa aaagttgaaa acttgctttt atactgaatt aaataaaaaa acaaactaaa     15720
     aagttcgggt ttcgacgggg attgaacccg tgaccacttc gacccaaacg aagtatgcta     15780
     ccactacacc acgaaaccac gttacaactc ataatacaaa tagataatat taatggtttt     15840
     ctccttccaa agtaattaag taaatatcat tgattttaaa aaagagctaa atacctaaag     15900
     aaattagcaa tcagagtatg gagaattatc tacttgcaac tactaagctg actgaatcta     15960
     tgccaaaaga agaacatgaa attgcttcaa atcaaattga tagaggacat aacaattact     16020
     taatttcgta gagttaaaat agttaatgtg agctaaacat gcaagtaact taaataatca     16080
     aatattatca ttgattaata attacgttca atttagaaag tgtttgtgca tcgaagcaaa     16140
     tatatttgtt ttagcaacat tctgatccct ttaaatagaa aatgttatct aaacgatcaa     16200
     aaaaatatcc taatctcgta attgatagaa atctctgcaa agatttccta ttaaatcgag     16260
     atatgttcct tattgcctaa aataaattaa aatcaatcct gtagatgact cgtggtctta     16320
     aaatgatact tttagaaaaa aaaaaatagg taaataagta acctaaccaa ttttacgagt     16380
     tatcagatac atagatttga ataatcaatt ataaaaatat attgattaat ttacttatgt     16440
     gcttaatatt tgaaatatgc tagtatttgc aacgtcttcg tgttcgcact ttatatttat     16500
     ttttgttatc ttttaagcgc ccaatagtaa aagaaattgt attccgatca atttttgcaa     16560
     ttttcgtgca gcttaaaaaa aaaatacttc tttgtctact caaaaagcat gaaaaggttt     16620
     acaataaatg aatactgaag ggttccataa agtataatat tttcaatgaa atatggttat     16680
     ataattcaat tattatttgc agtaaaattc aaatgcatct ttttcatata tctagtttta     16740
     taaaacaatt aatttttaga gagttaatga acgtgttcga taaatgcaaa agtaacacct     16800
     accctattcc aaaatctcac tattataaat aaataatcta gcaaatactt atttatattg     16860
     aatcatttat acacctccgt ttatgggttt gctacacaaa taaggcgtac ctagtgactc     16920
     tcgataaacc tccctaaaac ctaccctagc tcaaaaaggc agtcacaaat ttactaccaa     16980
     ttttagcagt gattattgaa acgaacaagc agcgttatat caaaatggta tgtataatat     17040
     gaatacctgt ttgttctatt aagctaatga gtgatttagg gaattgatat cgagagacat     17100
     cacgttaaaa agtctcaacg cagcaagcct gcttcggaga acgtctactt aaagcttttg     17160
     gttaagcttt accgtttttt ggcccgtcgt acagattccc gcttcaacaa ggctattttg     17220
     aagcgtcttt ttcaatccaa gactaaccgt cctcctattt ctatctcaaa gatcgctgct     17280
     ttaactagcc gtaagagtgc ttcttctcag aacaaaacca ccgtcgttgt cggaaccgtt     17340
     accgacgatg agcgtatgtt gactgttcct aagctttcta ttgccgctct tcgttttact     17400
     aaatctgctc gcgctcgtat tttgaaagct ggtggtgaag ttttaaccct cgatcagctt     17460
     gctctacgtg ctcccactgg aagcaacact gttcttgttc gtggtaagaa gcatgctcgt     17520
     gaggcttacc gtcactttgg ctttggtccc cacaagcata aggctcctta tgttcgttct     17580
     gagggccgta agttcgagag agctcgtggt cgcagaaagt ctcgtgcatt caaggtttaa     17640
     attaccttgt tcaagctcgt ttccttttct cacactttat gggatcagct cttagttgct     17700
     tctcatttgg ttagcgttca taaattaggt taccggtgca ttattgatcc ggctttagtg     17760
     tacatcaata gtgttcgttc ccagatatga atacaatgaa aatctaatag cttagttggt     17820
     taacattatt ctctttctaa ttttttaatc gtaaacgtat atgtacttgt aagacgatgc     17880
     ttttattgat ttaatattgg tgttagcagt tactttttgt atttcgcgct gcaggtcatt     17940
     attaattttt ttgtcgtcgg atttcaattt agtgagcacg agtgattttt actaaattcg     18000
     ttagccacac cgtgctattc gctattggat ttccattcct ccttccactt acaccgaatt     18060
     ttggagcaaa aaacgtcttc ttaagaaaaa aatgagtcgc agaagccttc gtacccttta     18120
     tgtgacagga tttcgagatg gaatgcgtgc tcgtgagctt gcttatgaat ttgagccgta     18180
     agttgttttt catgcacttt aaatagctaa tttattcatt tagttttggg cctttaatac     18240
     gttgcgacat cccaatccct agaactcgaa cttcaagacc gtaagtaaat ggctttctaa     18300
     gtaaagattt taaccgtctt attggatagt tttgcattcg ttgagtacga agattcccgt     18360
     gatgctgaag atgcgtatta tgaagtgcac ggacgtcgtc tcgaaagagg tggcggtgtt     18420
     cttcgtgtag aatgggccaa gcaaccacct ccgtcaggcc ctggctccaa acgtggtgga     18480
     agacgcgaac gaggaggtcg tgttcacgga gattctggac ggctacgttc aaggtcacct     18540
     agtccgcacg aagcccgatc tcgttcccct tataatgatg aacgatctga tagaagatca     18600
     atgagccctc gttatcgttc gcgtagtcgt agtcctgatg gacgtagtcg gtctcccgat     18660
     tatgatcgtc gttctcctaa acggaaccat cgttcacctt caccagtctc ttttgcacct     18720
     caaaagagcc cagtagagaa tgaaactgaa acgaatgttg ataatggtga cacaaaaatc     18780
     tctgagtcta acgaaaaatc tggcactgaa gttgaacaac aatctgcacc taactctaat     18840
     ggtaacgagg aagttaataa tcttgaacca gtcggtcaaa acgaaagtaa gcaagagcct     18900
     cctaaggaag agaactcaaa tgtctcacaa gagcaaccag aacaagccca acccgaagtg     18960
     tcagctgctt cagagcaacc agaatccaac cctactacta cagagtctca ataaactttt     19020
     gtacttaatt aaaaaaaggt tttcatgttt taaaaattgt ctatattcct ttacttttgt     19080
     tccaaaattc cgtaacacag ttaatgtcgt ttatccggct aaaactctga aatgtcatgt     19140
     ttgtgtaaat ctgtcctttt tttttcaggg cgctttattt ttttttagaa aataaaaccg     19200
     aagaaaaagc tcaacaattt ccacttttga ctgtgctgat tcgtggcaga ttttgctctg     19260
     aacagatgat ttagaatcca atttcttctc tcgctgttgc ttgaactttt atgccgtagg     19320
     tttatctcac aatataagct ttctttctca catcaattgt gtgatgccgc aaaaattgat     19380
     accatgaatg ttcctttgca tttatttatt tagcggtatg ctactgccaa acgcttgttt     19440
     gaattatggt atgatggtcg cttgtttcct tctttaaggg cacaacagtg tgctcaaaat     19500
     atatttagct tttgcaatta ctatgaaaat actttttgac ttctggattt tgtagactat     19560
     aattttgaca gttcactagt ttgagttaaa aatttttgta ataaaactat ctatttattt     19620
     atttatgcca ttttaatatc atatttcaac tttgttgttc gcacttctaa tttcagagct     19680
     ttttattacc agcagccttt gtttccaagg tattactgtt gaatacaact ttttcaacat     19740
     acatgtgtgt taatatttta cttttagttt ggacaccaaa atcgcataga caatttttaa     19800
     ctatatatca aattcatgaa gttttttagc aaaaaaccgt tattacttta cgtttataaa     19860
     tcataactaa aaaaaacaaa acaagaatat acaacaaagc tacgccaaaa ataaaaattt     19920
     tcttcaatgt caatttttta ttaagcaccc tttttaagca cgaccggcct caataacctt     19980
     ggcgttgaaa cgctctttgc gttcttcagc agtaagcttc ctttgagtat acttaagaga     20040
     ctcagccttg aaagcagcag catccttacc agacttctgg aaagaaggat cctcacggat     20100
     tttggcataa gcctcggcat agatgtcctc aagttgatcg ctctcaatac catcagcaat     20160
     caagccagag aattgctttt gataacgctc ttcatcatca tcaataagca tctccatgta     20220
     ttcagcaaca tgaccaccat agatatactt acggagagtc tcatcatcca attcctcagt     20280
     ttcaatatcg aaaccaggga aacggttggg agagtgggga ataaacaaac caccatcaga     20340
     agcacccttc attgcaccaa agacacggga accggtagaa gtacgcttca aaccaacatc     20400
     caagaaaacc ttgaaggggc gaggaccatc ctcaatagcc tcagtgagct cgaactcacc     20460
     ctcaggttca gtaacaccct catacttatc agcaaggcca accttagcaa gagcacgacg     20520
     agcgaccaaa agaccggtag cgtaggcggc agtccagttg gccaaacccc atttgatacc     20580
     gtaacgagga agctcagaag agtgagcgtg agcaagaaca tagtcaccgt ttactctgga     20640
     agaaactatt tggcatgtga cgaaacgatt ggagaaacga acgaccaaac ggtacttggg     20700
     agcattgtat ttgttcttgg cctgggcaat caaacgctta cgagcgtaat aatcggtttt     20760
     accctcacga cgacgacgat atttcgtctg ataacgtgaa aagtaagggc tgctcttgac     20820
     tgctttgata aagggcatgt cggtaaacgg acaaaagtat gatattattc ctaagtaatt     20880
     ttggatctta agtatttatg acagtcacaa atacttataa ccctacccta tttttcacaa     20940
     gggtagtatt tcaaaggata acgaagttta ctgctaaagc aaatgaagaa aatgaaatct     21000
     tgttttacgc ccttttcgtc gctgatttat gcttagatat gaaaggtgga ttaatagcca     21060
     taaataagcc ttctggtaga acctctgctc aatgcttaaa tggtaagtta tttagggagt     21120
     tttttgtatt tttcttttaa attaccatta atattcaatt acttgcaata attgttgtgc     21180
     aaactaaaat gatcctaact gacagaatta aaaaaaataa tttcaaacag tgagctagct     21240
     caatattttc ggcctgctcc tccacaccct aacgatcgta atcgaagacg aagaaaatca     21300
     aacagactac cagatataaa gattggacat ggaggtacct tagaccctct tgcttctgga     21360
     gttttggtag tgggattggg tacaggaaca aagcaacttt catcattact ttcatgtatg     21420
     aaaacttacc gagcgacagc cctgtttggc tgctcgacag atacctatga ttctgctgga     21480
     aaaataatta agattgctgt acacatccct actaaagagg aaatattatc tggtttagac     21540
     gcttttcgag gtgacatctc tcagttacct cctctttact ctgctctgca tattcaaggt     21600
     aagagactat atgagtatgc acgcgaagga attcctttac ctgaaagtat caaagcacga     21660
     tctatgcatt gcgaagaatt aattttaaaa gattttattc cgaaggaaga acacacctac     21720
     acggatccgg atgaatttgc ttcaaaggag gcaattgaaa gtgaggaact tttaagacct     21780
     attgagggag gtgccgaacg tcatgattta cttgcaaaga cagagcaaga catcaatccc     21840
     caagatggtg atgaaaaaat aaacgcgaag agtcccacta ccaattctgt tacagatgta     21900
     gccaaagatc aaactgtcac aaaccctaaa aaacgaaagt ttgaagtcac tgatttagcg     21960
     cgaggatcac gacctgcaat agggccaatt gcagtccttg atatgacggt ttcttctggt     22020
     ttctacgttc gctctttaat tcatgatttg ggccgacaag taaatagtga agcacacatg     22080
     gtcgatcttg tgagattgaa acaggggtct tttgcactag acgatgaaaa ctgctttgat     22140
     ttttcagaat tttcagctcc aggctgggag gaaaaactcg cagcagcgtt caaaatcgac     22200
     ctgaaaggag acgaaacaag ctgaagcagt cttaatatat ataccagtaa tatacttttt     22260
     agataaggac attcatattt tctttaaaag catataatag acatttcttt tccactccaa     22320
     gcaaatatta tcactggtac agtgaagaaa acgattttta tgaagaacac tgaaaccatc     22380
     aaccctttaa ttccttcaat gtagtaatac gctttaaatt tgcgtcgtgt ttcagataac     22440
     tttgtagctt atctgttcta acttgtcgac cttttcctcc ataaattact ttagtaatca     22500
//