ID   SPBC1105   standard; DNA; FUN; 34982 BP.
XX
AC   AL096851;
XX
SV   AL096851.1
XX
DT   16-JUL-1999 (Rel. 60, Created)
DT   07-MAR-2002 (Rel. 71, Last updated, Version 4)
XX
DE   S.pombe chromosome II cosmid c1105.
XX
KW   abp1; ars binding protein; conserved hypothetical; exo-beta-1,3-glucanase;
KW   hhf3; hht3; histone h3; histone h3.3; histone h4.3; homocitrate synthase;
KW   ribosomal protein; ubiquitin conjugating enzyme; zinc finger.
XX
OS   Schizosaccharomyces pombe (fission yeast)
OC   Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes;
OC   Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
XX
RN   [1]
RP   1-34982
RA   McDougall R.C., Rajandream M.A., Barrell B.G., Ramsperger U., Bothe G.,
RA   Pohl T;
RT   ;
RL   Submitted (16-JUL-1999) to the EMBL/GenBank/DDBJ databases.
RL   European Schizosaccharomyces genome sequencing project, Sanger Centre, The
RL   Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail:
RL   barrell@sanger.ac.uk and GATC GmbH, Fritz-Arnold-Str 23, D-78467 Konstanz,
RL   Germany
XX
DR   GOA; P09322; P09322.
DR   GOA; P10651; P10651.
DR   GOA; P49777; P49777.
DR   GOA; Q9URU6; Q9URU6.
DR   GOA; Q9Y812; Q9Y812.
DR   GOA; Q9Y813; Q9Y813.
DR   GOA; Q9Y818; Q9Y818.
DR   GOA; Q9Y819; Q9Y819.
DR   GOA; Q9Y821; Q9Y821.
DR   GOA; Q9Y822; Q9Y822.
DR   GOA; Q9Y823; Q9Y823.
DR   SPTREMBL; Q9URU6; Q9URU6.
DR   SPTREMBL; Q9Y811; Q9Y811.
DR   SPTREMBL; Q9Y812; Q9Y812.
DR   SPTREMBL; Q9Y813; Q9Y813.
DR   SPTREMBL; Q9Y814; Q9Y814.
DR   SPTREMBL; Q9Y815; Q9Y815.
DR   SPTREMBL; Q9Y816; Q9Y816.
DR   SPTREMBL; Q9Y817; Q9Y817.
DR   SPTREMBL; Q9Y818; Q9Y818.
DR   SPTREMBL; Q9Y819; Q9Y819.
DR   SPTREMBL; Q9Y820; Q9Y820.
DR   SPTREMBL; Q9Y822; Q9Y822.
DR   SPTREMBL; Q9Y823; Q9Y823.
DR   SPTREMBL; Q9Y824; Q9Y824.
DR   SWISS-PROT; P09322; H4_SCHPO.
DR   SWISS-PROT; P10651; H33_SCHPO.
DR   SWISS-PROT; P49777; ABP1_SCHPO.
DR   SWISS-PROT; Q9Y821; PMC4_SCHPO.
XX
CC   Notes:
CC   Details of yeast sequencing at the Sanger Centre are available on
CC   the World Wide Web.
CC   (URL, http://www.sanger.ac.uk/Projects/S_pombe/)
CC   During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced
CC   by the Sanger Centre.  The sequencing of the S. pombe genome is now
CC   being continued with funding from The European Commission.
CC   Fourteen European sequencing laboratories, including the Sanger Centre,
CC   are participating in the project.
CC   Protein coding regions (CDS) have been predicted with the help
CC   of computer analysis using the Genefinder program in PomBase
CC   (an ACEDB database) with additional predictions for the
CC   branch-acceptor sites supplied by the program Sp3splice.
CC   CAUTION: It is possible that for any individual CDS we may have
CC   underestimated or overestimated the number of introns/exons or
CC   we may not have chosen the correct splice donor/acceptor sites.
CC   CDS are numbered using the following system eg SPBC25H2.01c.
CC   SP (S. pombe), B (chromosome 2), c25H2 (cosmid name),
CC   .01 (first CDS), c (complementary strand).
CC   The more significant matches with motifs in the PROSITE
CC   database are also included but some of these may be fortuitous.
CC   The length in codons is given for each CDS.
CC   IMPORTANT: This sequence MAY NOT be the entire insert of
CC   the sequenced clone.  It may be shorter because we only
CC   sequence overlapping sections once, or longer, because we
CC   arrange for a small overlap between neighbouring submissions.
CC   Cosmid c1105 is overlapped at the 3' end by cosmid c887
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..34982
FT                   /chromosome="II"
FT                   /db_xref="taxon:4896"
FT                   /organism="Schizosaccharomyces pombe"
FT                   /strain="972h-"
FT                   /clone="cosmid c1105"
FT                   /map="IIR"
FT   CDS             join(1..434,477..941,984..1051)
FT                   /codon_start=2
FT                   /db_xref="SPTREMBL:Q9Y824"
FT                   /note="SPBC1105.01, len:307, LOW SIMILARITY:some to,
FT                   Saccharomyces cerevisiae, tr:Q12754, hypothetical 137.5 kD
FT                   protein, (1228 aa), fasta scores: opt: 389, E():3.5e-18,
FT                   (27.5% identity in 273 aa)"
FT                   /partial
FT                   /gene="SPBC1105.01"
FT                   /gene="SPBPB7E8.03"
FT                   /product="hypothetical protein; similar to S. cerevisiae
FT                   YPL012W- null lethal"
FT                   /protein_id="CAB50964.1"
FT                   /translation="ISAIVPVISRLYDSMNSVGDGSQALPKYVALERLKTWKLLFKLLP
FT                   NDEFHLLPSAIAEVVLFSKHHDDDLRAMAFELLVEVGNRMKNGGKINMSLIDGEEPNKT
FT                   VVEANINEYISMISANLMNDSLNLKVSTIFALTRIFYEFSDYIDDDYVNAVLEEVQSSL
FT                   QSNNQEIARAAVGFIKMYITSFTKSKVLFHLDTLLPLILRWIKEHNAYVKLKAKQLLDR
FT                   MLRVFSLKELEAFAENETDKEWLQRIWRVRRSRGDKKVVDNKRDASDSEDLAIKNPMNK
FT                   KAKVGKVDFRKHEKKLNKASMHRDKFSTGMHTSKRVQKKN"
FT   misc_feature    435..440
FT                   /note="gtatgc, splice donor sequence"
FT   misc_feature    462..476
FT                   /note="ctaactttaatccag, splice branch and acceptor"
FT   misc_feature    942..947
FT                   /note="gtatgt, splice donor sequence"
FT   misc_feature    972..983
FT                   /note="ctaacatttcag, splice branch and acceptor"
FT   CDS             complement(1597..2853)
FT                   /db_xref="GOA:Q9Y823"
FT                   /db_xref="SPTREMBL:Q9Y823"
FT                   /note="SPBC1105.02c, len:418, SIMILARITY:Saccharomyces
FT                   cerevisiae, HOSM_YEAST, putative homocitrate synthase,
FT                   mitochondrial isozyme (ec 4.1.3.21),(440 aa), fasta scores:
FT                   opt: 2111, E():0, (78.4% identity in 399 aa)"
FT                   /gene="SPBC1105.02c"
FT                   /gene="lys4"
FT                   /product="putative homocitrate synthase; mitochondrial
FT                   isozyme ; involved in lysine metabolism; similar to S.
FT                   cerevisiae LYS21"
FT                   /protein_id="CAB50965.1"
FT                   /translation="MSVSEANGTETIKPPMNGNPYGPNPSDFLSRVNNFSIIESTLREG
FT                   EQFANAFFDTEKKIQIAKALDNFGVDYIELTSPVASEQSRQDCEAICKLGLKCKILTHI
FT                   RCHMDDARVAVETGVDGVDVVIGTSQYLRKYSHGKDMTYIIDSATEVINFVKSKGIEVR
FT                   FSSEDSFRSDLVDLLSLYKAVDKIGVNRVGIADTVGCATPRQVYDLIRTLRGVVSCDIE
FT                   CHFHNDTGMAIANAYCALEAGATHIDTSILGIGERNGITPLGALLARMYVTDREYITHK
FT                   YKLNQLRELENLVADAVEVQIPFNNYITGMCAFTHKAGIHAKAILANPSTYEILKPEDF
FT                   GMSRYVHVGSRLTGWNAIKSRAEQLNLHLTDAQAKELTVRIKKLADVRTLAMDDVDRVL
FT                   REYHADLSDADRITKEASA"
FT   misc_feature    complement(1924..2733)
FT                   /note="Match to PF00682 HMGL-like, HMGL-like Score 383.51"
FT   CDS             complement(3832..4479)
FT                   /db_xref="GOA:Q9Y822"
FT                   /db_xref="SPTREMBL:Q9Y822"
FT                   /note="SPBC1105.03c, len:215, SIMILARITY:Saccharomyces
FT                   cerevisiae, RM16_YEAST, mitochondrial 60s ribosomal protein
FT                   l16 , (232 aa), fasta scores: opt: 542, E():2.1e-29, (47.1%
FT                   identity in 153 aa)"
FT                   /gene="SPBC1105.03c"
FT                   /product="mitochondrial ribosomal protein L16"
FT                   /protein_id="CAB50966.1"
FT                   /translation="MALQQYNKFPFFFSGILGPTRLNGLQMPPIQTMVRWGHQYAPRSI
FT                   RNQKAQKGRVPIPIGGSLRGTQLEWGEYGMRLKDRSIRFHAKQLETAEQILKRILKPIK
FT                   AARVYTRFCCNVPVCVKGNETRMGKGKGAFEYWAARIPIGRVLFEIGGDGMRKELAEHA
FT                   LKQAAFHLPGKYEIIVKQTPKRLGTTLIHETPITTETSKMNYQEITSTTTAV"
FT   misc_feature    complement(3946..4362)
FT                   /note="Match to PF00252 Ribosomal_L16, Ribosomal protein
FT                   L16 Score 133.40"
FT   CDS             complement(6317..7885)
FT                   /db_xref="GOA:P49777"
FT                   /db_xref="SWISS-PROT:P49777"
FT                   /note="SPBC1105.04c, len:522, identical to
FT                   Schizosaccharomyces pombe, ABP1_SCHPO, ARS binding protein
FT                   1, except for a single amino acid difference at aa 336
FT                   (C-S)"
FT                   /gene="abp1"
FT                   /gene="SPBC1105.04c"
FT                   /gene="cbp1"
FT                   /product="ARS binding protein; binds to centromeric DNA
FT                   sequences; required for mitotic and meiotic chromosome
FT                   segregation"
FT                   /protein_id="CAB50967.1"
FT                   /translation="MGKIKRRAITEHEKRALRHYFFQLQNRSGQQDLIEWFREKFGKDI
FT                   SQPSVSQILSSKYSYLDNTVEKPWDVKRNRPPKYPLLEAALFEWQVQQGDDATLSGETI
FT                   KRAAAILWHKIPEYQDQPVPNFSNGWLEGFRKRHILHAINEQPTESVVLNNTEPPNDPL
FT                   SRVYDVTRLTNINDIFTMQETGLFWKLVPNGTPEVEDIKGITRFKARITLTVCCNASGT
FT                   ERLPLWVIGYSQSPRVFRAANVKPEVMNFKWRSNGKASMTTAIMEEWLRWFDACMEGRK
FT                   VILLIDSYTPHLRAVENIRNSGNDLRNTTVITLPSTSASISQPCSEGVIYALKACYRKH
FT                   WVQYILEQNELGRNPYNTTNVLRAILWLVKAWTTDISPEIIENAFNLSGVLGLFNESAV
FT                   TSRALDEMIHPLRELVSEFSVQAAMRIEDFISPSEENIVDSSEDIINQIASQYMDDRAF
FT                   ETDEEESTEFQITTKDAMKAIELLLNYEAQQPDGNPAITISLLNYQKLLEARGGNVNLS
FT                   RLRST"
FT   CDS             10684..11907
FT                   /db_xref="GOA:Q9URU6"
FT                   /db_xref="SPTREMBL:Q9URU6"
FT                   /note="SPBC1105.05, len:407, SIMILARITY:Hansenula anomala,
FT                   CAA11018, exo-beta-1,3-glucanase, (427 aa), fasta scores:
FT                   opt: 942, E():0, (43.1% identity in 420 aa)"
FT                   /gene="SPBC1105.05"
FT                   /gene="exg1"
FT                   /product="exo-beta-1,3-glucanase"
FT                   /protein_id="CAB50968.1"
FT                   /translation="MLSFTSVFSFFLHALLLKTAFSYVIKRNNPVFDYTSEKVRGVNIG
FT                   GWLVLENWITPQLFTQFSSMSNPPTDEWGFCEVLGADEAASQLAAHYSSFYTESDFATI
FT                   ASWGVNVLRIPIGYWAFNVVDGEPYVQGQEYWLDQALTWAEQYGLKVWIDLHGVPGSQN
FT                   GFENSGKTGSIGWQQNDTVTRTLDIITYVANKYTQSQYASVVIGIETVNEPLGYGLDMD
FT                   QLKQYDLDAYNIVNPLSSSVATIIHDAYVDLSIWDYGVVSPSSYNLVMDVHRYQLYESD
FT                   ECSKTLDDHLSDVCSIGDSIASSPYITVTGEWSGTLADCTIFEEGVDSSTFIGPNSGDI
FT                   STWTDEYKGAVRLFIETQLDQFERGAGWIYWTAKTGGPSPTWDMGLLIEYGVFPQPFTD
FT                   RQYSSYCG"
FT   CDS             13035..13754
FT                   /db_xref="GOA:Q9Y821"
FT                   /db_xref="SWISS-PROT:Q9Y821"
FT                   /note="SPBC1105.06, len:239,"
FT                   /gene="SPBC1105.06"
FT                   /gene="pmc4"
FT                   /product="RNA polymerase II holoenzyme and mediator
FT                   subcomplex component;  similar to S. cerevisiae MED4;
FT                   involved in regulating RNA polymerase II activity"
FT                   /protein_id="CAB50969.1"
FT                   /translation="MEYQRAIDSIEECLNKQLRLSSEKVDQYVLIENWTSLVGHLKTLH
FT                   SLISNYTNGRELQNEISSLLKQDKELDLQIQDCMREMTSIYDTHLPKTVSGRKRQKVNA
FT                   ETLLDYGRKLSKFSSAPPGYNPETGQDAKAPVHYPWPSEDQMRKTLLFQFSTSMVPNLS
FT                   ATASQLFSEQPPKTNEPTETETEIDANKAVEEKTKMNYPASPTFTTQEENKEVESPANK
FT                   DVFAGFDLFDPEMEEDF"
FT   CDS             join(complement(15419..15550),complement(15195..15352),
FT                   complement(14650..15147),complement(14343..14594),
FT                   complement(14012..14300))
FT                   /db_xref="SPTREMBL:Q9Y820"
FT                   /note="SPBC1105.07c, len:442, SIMILARITY:some to,
FT                   Caenorhabditis elegans., YPI7_CAEEL, hypothetical 83.8 kD
FT                   protein c27f2.7 in chromosome iii., (731 aa), fasta scores:
FT                   opt: 328, E():7.6e-15, (27.3% identity in 286 aa)"
FT                   /gene="SPBC1105.07c"
FT                   /product="conserved protein; putative PINT domain"
FT                   /protein_id="CAB50970.1"
FT                   /translation="MSLNDFLQTLSNAVGEKNSNTLEKCIILDPSEPSFQQLSKTLFLD
FT                   RKGKNKLNGTIQKEFGRIRGWKELVTTYFEYVENAASSPDQRKWELLQNLYSNLTTCFS
FT                   HIDGAWLCTIVKRVSKLYVKLSLQLDTSTPTLEDSFDGNGFIQRKYVSDASRNVLRTFN
FT                   SILSDRQQNINPSKKDAIFCIANLLCLLYFRLKQIRLCQTIQANVISSGADISRATMAE
FT                   LVTFRYYLGRCHLYQRKIHQAKDHLLFSFLQCPDECYHQKRLSLIYLTTCLLILGKSPT
FT                   KGLLEKYKLTAAFEPLIKALKSGDIKSFRLSLEDNSRRKWFIKRGIYLTLLDRCEIILW
FT                   RNLFRKVFLFTFEQSQKTPHVSGSYLLTAARLSTNDNSYDMDDVECICVSLIDQGYIKG
FT                   YIIHASSTLVLKKDPSFGFSVIESLMPIARNDHAEKEFFHANA"
FT   misc_feature    complement(14301..14313)
FT                   /note="ctaatttaaaaag, splice branch and acceptor"
FT   misc_feature    complement(14337..14342)
FT                   /note="gtacgt, splice donor sequence"
FT   misc_feature    complement(14595..14607)
FT                   /note="ctaatcaaaaaag, splice branch and acceptor"
FT   misc_feature    complement(14644..14649)
FT                   /note="gtatgt, splice donor sequence"
FT   misc_feature    complement(15148..15166)
FT                   /note="ctcacttttgtttttctag, splice branch and acceptor"
FT   misc_feature    complement(15189..15194)
FT                   /note="gtaatt, splice donor sequence"
FT   misc_feature    complement(15353..15367)
FT                   /note="ctaaccgtgataaag, splice branch and acceptor"
FT   misc_feature    complement(15413..15418)
FT                   /note="gtatgt, splice donor sequence"
FT   CDS             join(15907..16105,16254..17944)
FT                   /db_xref="GOA:Q9Y819"
FT                   /db_xref="SPTREMBL:Q9Y819"
FT                   /note="SPBC1105.08, len:629, SIMILARITY:Caenorhabditis
FT                   elegans., Q94422, zk858.6 protein., (656 aa), fasta scores:
FT                   opt: 1472, E():0, (37.9% identity in 610 aa)"
FT                   /gene="SPBC1105.08"
FT                   /product="putative endosomal membrane protein; similar to
FT                   S. cerevisiae EMP70"
FT                   /protein_id="CAB50971.1"
FT                   /translation="MLLPSIPSCSFSFVVFVSVLLQTCFSFQLTPLSPKNYPPGASIDT
FT                   TVNTISPFIGDGRGSDIFNYEYYDERFHFCRPENIAKQSESLGSVLFGDRLYNSPIEIK
FT                   MLENQDCVPLCASIIPSSDVSFIRDLISKNYVVNWNIDNLPVATYLEGTNSKNYSLSPG
FT                   FPLGKNTEKGVILFNHYDIVIEYHTTSSDQHRVVGAYVKPVSKESTLVDGNPVCSSSSN
FT                   PQYLPEGADLTLVTSYSVSWKYSDTPWATRWDKYMHIESRQIRWIFIIHSAIIDTFLIF
FT                   VVSIILYRTLNRDINKYNSAFVDQEDVQEDFGWKLVHGDVFRPPRRPMLFSILLGTGAQ
FT                   LLFMSSGIVLFAIFGIVAPSRRGSLATATVALFIISGFVSGYVSALSYKLMQGMLRKRN
FT                   LLLTPFVVPGFMLAAALFFNMVFWSKSSSSTVPFSSWLLLIFLYLLFTVPLSFVGSLIG
FT                   FRSREFVPPVRTNQIPRQIPSHSIWLSSFPSAIIGGSIPFLVILIELFSILDSLWFHPL
FT                   YFMFGFSFFCFGILVTTCIMVSIITVYFQLCSENYNWWWRSFITPGFCGIYVFIFSVFY
FT                   WFFKISSSSLATAVLYFGYSLLISVLVFFLCGSVGFFGAFLFVNKIYASIKID"
FT   misc_feature    16106..16111
FT                   /note="gtacgt, splice donor sequence"
FT   misc_feature    16239..16253
FT                   /note="ctaacttcactttag, splice branch and acceptor"
FT   CDS             join(18421..18465,18548..18691,18770..18799,18876..19101,
FT                   19172..19230)
FT                   /db_xref="GOA:Q9Y818"
FT                   /db_xref="SPTREMBL:Q9Y818"
FT                   /note="SPBC1105.09, len:167, SIMILARITY:Zea mays, O22656,
FT                   ubiquitin-conjugating enzyme e2, (169 aa), fasta scores:
FT                   opt: 795, E():0, (65.7% identity in 169 aa)"
FT                   /gene="SPBC1105.09"
FT                   /EC_number="6.3.2.19"
FT                   /gene="ubc15"
FT                   /product="ubiquitin-conjugating enzyme"
FT                   /protein_id="CAB50972.1"
FT                   /translation="MPSSASEQLLRKQLKEIQKNPPQGFSVGLVDDKSIFEWEVMIIGP
FT                   EDTLYEGGFFHATLSFPQDYPLMPPKMKFTTEIWHPNVHPNGEVCISILHPPGDDKYGY
FT                   EDAGERWLPVHSPETILISVISMLSSPNDESPANIDAAKEFRENPQEFKKRVRRLVRRS
FT                   IEMI"
FT   misc_feature    18466..18471
FT                   /note="gtaagc, splice donor sequence"
FT   misc_feature    18535..18547
FT                   /note="ctgatagatatag, splice branch and acceptor"
FT   misc_feature    join(18548..18691,18770..18799,18876..19101,19172..19212)
FT                   /note="Match to PF00179 UQ_con, Ubiquitin-conjugating
FT                   enzyme Score 221.29"
FT   misc_feature    18692..18697
FT                   /note="gtatgt, splice donor sequence"
FT   misc_feature    18752..18769
FT                   /note="ctaacctcgaaaaattag, splice branch and acceptor"
FT   misc_feature    18800..18805
FT                   /note="gtatat, splice donor sequence"
FT   misc_feature    18863..18875
FT                   /note="ctaacggtaacag, splice branch and acceptor"
FT   misc_feature    19102..19107
FT                   /note="gtgagt, splice donor sequence"
FT   misc_feature    19158..19171
FT                   /note="ctaactttttccag, splice branch and acceptor"
FT   CDS             join(20219..20305,20421..24227)
FT                   /db_xref="SPTREMBL:Q9Y817"
FT                   /note="SPBC1105.10, len:1297, SIMILARITY:Saccharomyces
FT                   cerevisiae, YJ03_YEAST, hypothetical 154.9 kD protein in
FT                   cpr7-pet191 intergenic region., (1357 aa), fasta scores:
FT                   opt: 639, E():0, (25.0% identity in 1337 aa)"
FT                   /gene="SPBC1105.10"
FT                   /product="possibly involved in regulation of (H+)-ATPase in
FT                   vacuolar membrane; similar to S. cerevisiae RAV1"
FT                   /protein_id="CAB50973.1"
FT                   /translation="MPLAFTNPGTPLKRTAAYDNVQWNQNRILTFGTRYTVLIIVNNYE
FT                   SYQNIQFGESIGAVALDQRTGFLAIAHGQVLDIYKPADSLKWTHHYNYITQLSEDITQL
FT                   SWGYNFDLLLCASSYTKLINFSEDKPRLVWSQNRISDSFLSSTISSDACFIASIETKNP
FT                   LAKVWQRTSPQGTVSSCDDFSYLVHPCRVRFSQWSKHLHPDASGSTPFLSTVGYDNVLR
FT                   IWQVGSRFGSQLMHLSCFLNLRKYYKSDQPPYCCFIDKDDFTIALAHAISRHSGQVHKD
FT                   RILNRLLALASGQPHIFLLFTFECLYIFSLVIDQETLSSFELINQVPTNFPKGALQPDG
FT                   FIPIYRTSKHEFYDYNIILFFQNSAREYMFSLTDFFYSDFELRVSYDFYGHDYPIKSLT
FT                   RTSNGHGIVSRDVNRICMFQSYISQDGKNQLICRFRLLLGESDFILPLYAGEYAAVLNL
FT                   NSLKLWHCNEAIPPTLLCTCRQVPTSPIITFFILPVQNNDNSALCALTEGGHAWFWSVS
FT                   NEAHDGSAVLRFIDRVNFTKNLNIASAVDVMGWSSTLNLSSLSSFDQEVFQSISKDGLL
FT                   QTWMARVLGDDKAEISEISKVQTSIKSATMIKGSTSKKVAVVSENNRRLSIFDTRSSEF
FT                   SEKEEFSSVFDDYGPINDLDWTSTPNSHSILAVGFLHDVILLCQNRRSYMNDIPCWSRI
FT                   RRYNLLEYTNSLISDSSWLDNGTLVTAIGNGLFYFDNSLPEDQSLLFPASLKRSAKNIF
FT                   DLAYQLNGILPVFHPQLLQQLLLRNQPFLFTNILLRFYLCLKDDVDMHFLLNMDCSEFY
FT                   CCDEEISKDLLIKSLSQNSAEILNPAELDFEETSVSKHLGLYIDEMIKKLTALLKVKKV
FT                   KTLTRSSQFLLLNLIEAFNKARALRDSLDLNGKRYCIMLNQYVLSKHQRQLTSLPTREM
FT                   AWAFHSSNKAVLLDHTKKLHGKPLLWNAVEEYAIPFWLNEQLLKDVFLELSRNHYAEID
FT                   DRNPENVSLYHIALHKINVFRDLWRLASWHKESARTVKLLSNDFSKKKWKVVASKNAFA
FT                   LLSKHRYFYASAFFLLADSCYDAAKVCIRNLKSISLAIAMTRVYEGDDGPTLKRLINEY
FT                   VLPLAVSQNDRWLTNWSFTILKQEKKALQSLVSPIRSLVSDNDFIQLYTSDKNDQEIHE
FT                   NKDSQRNSTNEPVRNKFPSDDPAFILLYECLRSSNVQIDESLEYRFVLHNANVYCQLGC
FT                   DLIALGLLRNWKFQKNPATAHLETEDYMVTDKQSAVEKTHDSPKLGKTLMGQDIRPTPD
FT                   DVPEFNESAFSFE"
FT   misc_feature    20306..20311
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    20406..20420
FT                   /note="ttaactaaatggtag, splice branch and acceptor"
FT   CDS             complement(24665..25075)
FT                   /db_xref="GOA:P10651"
FT                   /db_xref="SWISS-PROT:P10651"
FT                   /note="SPBC1105.11c, len:136"
FT                   /gene="hht3"
FT                   /gene="SPBC1105.11c"
FT                   /gene="h3.3"
FT                   /product="histone h3"
FT                   /protein_id="CAB50974.1"
FT                   /translation="MARTKQTARKSTGGKAPRKQLASKAARKAAPATGGVKKPHRYRPG
FT                   TVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQEAVEAYLVSL
FT                   FEDTNLCAIHGKRVTIQPKDMQLARRLRGERS"
FT   CDS             25313..25624
FT                   /db_xref="GOA:P09322"
FT                   /db_xref="SWISS-PROT:P09322"
FT                   /note="SPBC1105.12, len:103"
FT                   /gene="SPBC1105.12"
FT                   /gene="hhf3"
FT                   /gene="h4.3"
FT                   /product="histone h4"
FT                   /protein_id="CAB50975.1"
FT                   /translation="MSGRGKGGKGLGKGGAKRHRKILRDNIQGITKPAIRRLARRGGVK
FT                   RISALVYEETRAVLKLFLENVIRDAVTYTEHAKRKTVTSLDVVYSLKRQGRTIYGFGG"
FT   misc_feature    25316..25597
FT                   /note="Match to PF00125 histone, Core histone H2A/H2B/H3/H4
FT                   Score 47.19"
FT   CDS             complement(27306..27734)
FT                   /db_xref="SPTREMBL:Q9Y816"
FT                   /note="SPBC1105.13c, len:142,"
FT                   /gene="SPBC1105.13c"
FT                   /product="hypothetical protein; sequence orphan; low
FT                   correlation score; shows expression on microarray"
FT                   /protein_id="CAB50976.1"
FT                   /translation="MITEFIKSFLLFFFLPFFLSMPMIFATLGEFTDDQTHHYSTLPSC
FT                   DLLLIRGEVKENARCFLHNPKISHQHHSFWSLIEGCLEALQFGLLAILQGLFSQFAWEA
FT                   CSCTFACMLLTSERTEPSYPFSEITEVSRGGLHFVKLN"
FT   CDS             28477..30390
FT                   /db_xref="SPTREMBL:Q9Y815"
FT                   /note="SPBC1105.14, len:637, SIMILARITY:some to,
FT                   Saccharomyces cerevisiae, MSN2_YEAST, zinc finger protein
FT                   msn2, (704 aa), fasta scores: opt: 299, E():2.3e-08, (21.6%
FT                   identity in 672 aa)"
FT                   /gene="SPBC1105.14"
FT                   /product="zinc finger protein; zf-C2H2 type; putative
FT                   transcriptional activator; multistress response genes;
FT                   similar to S. cerevisiae MSN2"
FT                   /protein_id="CAB50977.1"
FT                   /translation="MDTTNNTYARSISSNGNDNFPTPDWQFNGSQLQQNRKSKMNGRSV
FT                   TNVFPNAFSDAEFEQISMPELNLKRFNPTTLEENNSDLSDMSSWDYMMNVPIRVYNDAD
FT                   TMDPFSLDTIPDSSMDMPFDPLASDYGNAANFPSVPSSLGSNHQFITTPPVNGSNEPTS
FT                   AQTNHIITANSSPSGNAGSNASASMSVPPPLTPSASTINDQPFSNSFDLPSQVIADGTG
FT                   AISDINGNPFPMNSPPLDMEPLPSISMDASDSVSEQLVKDASLPSGPFSTDYLENGSDL
FT                   KRSLGHNQKSDRVSKDVSPQHQANPSTLNNPLKTQNFDSSKNLYTDNKDSSLVSPTGLQ
FT                   SRMEQNPEVRAHPMKDSATSTALRRSHALGAAADSLLPQENSAQIYDGKDVSMVNDNMH
FT                   SDVRQDSFNKESIKQRIPSLSPPITRSYNAKHRPSLVLGTSVNPHSLSPSQPPVVVPSN
FT                   TTISSSPPLTSPVKTSANIPNLLPTSELDSSNAPHSQSAATHDLNDVKSYYNTRSSHSV
FT                   VPNPTNQKVSITGAAADGPNGSAPVDTTPTNSSTTATGAQRKRRKFKFGKQIGPVRCTL
FT                   QNRVTGEICNTVFSRTYDLIRHQDTIHAKTRPVFRCEICGDQRHFSRHDALVRHLRVKH
FT                   GR"
FT   CDS             complement(30949..31851)
FT                   /db_xref="SPTREMBL:Q9Y814"
FT                   /note="SPBC1105.15c, len:300, SIMILARITY:Saccharomyces
FT                   cerevisiae, YHM7_YEAST, hypothetical 33.1 kD protein in
FT                   ssf1-dys1 intergenic region., (280 aa), fasta scores: opt:
FT                   185, E():1.8e-05, (27.6% identity in 304 aa)"
FT                   /gene="SPBC1105.15c"
FT                   /product="hypothetical protein; similar to S. cerevisiae
FT                   YHR067W"
FT                   /protein_id="CAB50978.1"
FT                   /translation="MSAKVVLKDFLSQAPIDKLKATLSGHLPVSCITMDAKITSLQPGY
FT                   HFLFFSLASPESNLNSDGYESLYSPKPNNPFSFKRRIWLHGVLRFHRPLHLFQTSECHE
FT                   LIQEESVKSPSITKEVEACLPKSSFLTKPTSEKQTKHVYIRRKIYDSQHQLCIEEDRTL
FT                   AYLNRQELAIPKTLRSKSIPQHSWVFTPTPIMVFRYSALMFNAHMIHWNATYATKSENY
FT                   PNLVLPGPLLVTSMLEYFRSVYPQMSKNMKRFEFRLLSPAFVNQPLRICISETGNLWID
FT                   RFTTDLDPPSLIARGRVYT"
FT   CDS             complement(33106..33429)
FT                   /db_xref="GOA:Q9Y813"
FT                   /db_xref="SPTREMBL:Q9Y813"
FT                   /note="SPBC1105.16c, len:107, LOW SIMILARITY: Pyrococcus
FT                   horikoshii., O59248, 120aa long hypothetical protein, (120
FT                   aa), fasta scores: opt: 149, E():0.00037, (25.3% identity
FT                   in 99 aa)"
FT                   /gene="SPBC1105.16c"
FT                   /product="putative RNase P subunit; similar to S.
FT                   cerevisiae RPR2;  possibly involved in tRNA processing"
FT                   /protein_id="CAB50979.1"
FT                   /translation="MSTKSKDQHARVSYLYQASQLLFRNVQEPTLSRHYISTAKDVSQK
FT                   SVMRIHPDIKRTICKGCNSLLVPGKSCSIRFEEPSRKNPSIDRVLWICKKCAFKKRFSD
FT                   KSC"
FT   CDS             34147..34509
FT                   /db_xref="GOA:Q9Y812"
FT                   /db_xref="SPTREMBL:Q9Y812"
FT                   /note="SPBC1105.17, len:120, variant, as missing approx. 25
FT                   N-terminalresidues which are common to other Histone H3s,
FT                   SIMILARITY:Plasmodium falciparum., Q27719, histone h3, (136
FT                   aa), fasta scores: opt: 449, E():3.7e-25, (66.1% identity
FT                   in 118 aa)"
FT                   /gene="SPBC1105.17"
FT                   /gene="cnp1"
FT                   /product="inner centromere protein; histone H3 variant;
FT                   essential; required for equal chromosome segregation;
FT                   similar to S. cerevisiae CSE4"
FT                   /protein_id="CAB50980.1"
FT                   /translation="MAKKSLMAEPGDPIPRPRKKRYRPGTTALREIRKYQRSTDLLIQR
FT                   LPFSRIVREISSEFVANFSTDVGLRWQSTALQCLQEAAEAFLVHLFEDTNLCAIHAKRV
FT                   TIMQRDMQLARRIRGA"
FT   misc_feature    34150..34503
FT                   /note="Match to PF00125 histone, Core histone H2A/H2B/H3/H4
FT                   Score 38.21"
FT   CDS             complement(34750..34982)
FT                   /codon_start=3
FT                   /db_xref="SPTREMBL:Q9Y811"
FT                   /note="SPBC1105.18c, len:76, SIMILARITY:Saccharomyces
FT                   cerevisiae, Q05863, chromosome xii cosmid 8003., (155 aa),
FT                   fasta scores: opt: 101, E():1.3, (29.0% identity in 62 aa).
FT                   Overlaps and extends cosmid c887 CDS SPBC887.21c"
FT                   /partial
FT                   /gene="SPBC1105.18c"
FT                   /gene="SPBC887.21c"
FT                   /product="hypothetical protein; similar to S. cerevisiae
FT                   YLR281C"
FT                   /protein_id="CAB50981.1"
FT                   /translation="SQDTRSREQNRCIARKRLTEKVDEFKHGNDSLLARKVQRIVKKKK
FT                   QREKKSKRKYGNKIDDQDSSLNNNEAKQDVI"
FT   misc_feature    34979..34982
FT                   /note="nominal overlap with cosmid SPBC887, EM:AL033388 S.
FT                   pombe chromosome 2"
XX
SQ   Sequence 34982 BP; 10931 A; 6399 C; 6211 G; 11441 T; 0 other;
     gatctctgct atagttcccg ttatatcccg gttatatgat tcgatgaaca gcgttggtga        60
     tggcagtcag gcactaccca aatatgtcgc acttgaacga cttaagactt ggaagctttt       120
     atttaaactc cttcctaacg acgagtttca tcttttgcct tctgccatcg cagaagttgt       180
     gttattttct aagcaccatg acgatgactt gcgtgctatg gcttttgagt tgctagtgga       240
     ggtaggaaat cggatgaaga atggggggaa gataaatatg tctctaatcg atggagagga       300
     accaaataaa acagttgtgg aagcaaacat taatgaatat atttcaatga tttctgctaa       360
     cctcatgaac gattctttga acttgaaagt ttctacgatt tttgctctca caagaatctt       420
     ttatgagttt tctggtatgc attatatatc ttgtaaattt tctaacttta atccagatta       480
     catagatgat gattatgtaa atgctgtact tgaagaagtg cagtcgagtt tacagtctaa       540
     caatcaagaa atcgctcgtg ccgccgtagg ttttatcaaa atgtatatca cttcttttac       600
     aaagtctaag gttttatttc atttggatac tttacttcct ttaattcttc gatggatcaa       660
     agagcataat gcgtatgtca agttaaaggc caaacaactt ctggatcgta tgctgagagt       720
     gttttcatta aaggaactag aagcatttgc agagaatgag actgataaag aatggttgca       780
     acgaatttgg cgcgtacgtc gttcaagagg tgataaaaaa gtcgtggata ataaaaggga       840
     tgcttccgat agtgaagatt tggcaatcaa aaatcctatg aacaaaaaag caaaagttgg       900
     taaagtggat tttcgaaaac acgagaagaa acttaacaaa ggtatgtttt tttaataaga       960
     atctttgttg actaacattt cagcttctat gcatcgtgat aaattttcga ctgggatgca      1020
     cacgtctaaa agggttcaaa aaaagaatta aggaagagta tatctgtacg aatgcataga      1080
     atggataatt ttaggtgcca tattttttag agtaatttca tttaagaaaa atcactggtt      1140
     acaaggggtt taaattattt tttacaaaag gtaataatag gtttgaaaaa ttatataaaa      1200
     atacgcatta actttacata aaatgaagta gcaaggaagt aattccttga gcgtgctaat      1260
     ataaattttc aaattaaaat attttatttt aatagaataa aaacgataaa taatgtttgt      1320
     catatatcac cttaaaacat aaaacgaccc aaaagtaaaa gcaaccagat ataacattgc      1380
     aataaggctt gaagcaggaa taattgtgat ctttaaaaga acacataaag agaaaaaaac      1440
     ttttttaatg atcaatatca agacactacg taaaagaacc agcacttgca acgaaaaaaa      1500
     attttttaat agatatacat gcgaaacata tatacaatgc aagccaagaa gagaggagtt      1560
     aaatttttaa aattggggct aataatcact tccaatttaa gcagacgctt ctttggtgat      1620
     tctatcagca tcactcaagt cagcatggta ttcacgtaga acacgatcaa catcatccat      1680
     ggctaaagta cggacatcag ccaatttctt gatgcgaacg gtaagttcct tggcttgggc      1740
     atcagtaaga tgaaggttaa gctgctcagc acgagatttg atggcattcc aaccagtcaa      1800
     acgagagcca acatgaacat aacgactcat gccaaagtcc tcgggcttaa gaatttcata      1860
     tgtagaaggg ttagcgagaa tagctttagc atggatacca gccttatggg taaaagcaca      1920
     cattccggta atgtaattgt tgaaaggaat ttgaacttca acggcatcag cgacaaggtt      1980
     ttcaagctca cgtaactggt taagcttgta tttgtgggta atgtattccc tatcggtgac      2040
     atacatacga gccaacaagg caccaagagg agtaatacca ttacgctcac caataccaag      2100
     aatggaagta tcgatatggg tagcaccagc ttccaatgcg caataggcat tagcaatagc      2160
     cataccagtg tcattgtgaa aatgacattc aatatcacaa gagacaacac cacgtaaggt      2220
     acgaataaga tcgtagactt ggcgaggagt agcgcaacca acggtgtcag caataccaac      2280
     acggttgacg ccaatcttgt ctacagcctt gtagagagaa aggagatcga caagatcaga      2340
     acggaaagaa tcctcagatg aaaagcggac ttcaataccc ttgctcttga caaagttgat      2400
     aacttcggta gcgctgtcaa taatgtaagt catgtccttt ccatgggaat atttgcgaag      2460
     atattgagaa gttccgataa caacatcaac accatcaact ccagtctcaa cagcgacacg      2520
     agcgtcatcc atatgacagc gaatatgagt taaaatttta cactttaagc ccaatttgca      2580
     aatagcttcg caatcttggc gggactgctc agaagccacg ggagaagtca attcaatgta      2640
     atcgacacca aagttgtcca atgccttagc aatttgaatt ttcttctcgg tgtcgaaaaa      2700
     agcgtttgcg aattgctcac cttcacgaag agtagactca ataatggaaa agttattgac      2760
     acgtgaaaga aaatcagatg ggttgggacc ataagggttt ccattcatag gaggcttgat      2820
     ggtctcagta ccattagctt cggacacaga catgttgatg actttaaaat gcaaaaaaag      2880
     gaaaaggaaa agcgaatttt ctaaaatgaa ttaagtataa atatataaat tatacaattc      2940
     aacaacttat tgtcccgaaa cctgttagct ttgaattttt taagctaaat cttttatcac      3000
     tgtagaggag acaactaaga gcaaggatgc acgtatgtat gaatttcaaa aaattcgacc      3060
     ctaccctatt tatttactga aagaaacagt cactaccaac tcgtaggcaa ccgcggtaat      3120
     ttatggtaga aaattgattt acagatcccg atcgatcttg atgagattta atcagatcta      3180
     tggtagtaat gattaagtta ctgatccact caacagtgga ttgctaagct aggttctaga      3240
     aggtatagtg attttttttg taaacgttgt aaatatttta gtggagttga tttgaataat      3300
     ttcattcgta attccatagt aaaatcagtt tcatattatt taaagtgtac tttttgattc      3360
     acttcatgat ttcgcacata tacaacgtgc cgttttttac atcccgaaaa aaagtcccca      3420
     acggagcaga gagcagcaaa taagattttc gccaaaaaca ctcattaccg ttaccaactt      3480
     ttcaggacca aagaaatttg atgttttaac gaaattgccg agccgtaatc aaagtgaatc      3540
     aaaagtggtt catatttcgc caacaaaaat taagcaactc tctcattggg gatgaaagtt      3600
     cccatttcga aaatagataa tgaaacatag cgcaaaatgt acaatgtttt aaggcatttc      3660
     tggcaaattt cattcactaa aacatagaat aactacaacg attgaaaaga agctcatgaa      3720
     tgtctgtaca aagatgcagc attaagttca caaactaagt aagtgagaag tatgacagaa      3780
     aagtaattat tgaatgggtt aaaaatagat aaattcagct taacttttcc cttaaacagc      3840
     tgtagtagta ctggtaattt cctgatagtt cattttgctt gtctcggtgg taatgggggt      3900
     ttcatgaatc agtgtggtac ccaatctttt gggggtttgc ttgacgataa tctcatactt      3960
     gcctggaagg tgaaaagcgg cttgcttcaa tgcatgctca gctaactctt tacgcattcc      4020
     atcaccacca atttcaaaaa gtacacgacc gattggtatc cgtgcagccc agtattcaaa      4080
     agctcctttg cctttgccca tacgagtttc atttcctttt acgcatactg gcacattgca      4140
     acaaaaacgt gtgtataccc gagcagcctt gataggtttt aatatacgct tgagaatctg      4200
     ttcggcagtt tcgagttgct tggcatgaaa tcttatactt cgatctttta atcgcatacc      4260
     atattctccc cattcaagtt gagtaccacg tagtgaacct cctatgggta tagggactct      4320
     tcctttctga gctttttggt ttctgatgct tctgggtgca tactggtgtc cccaacgaac      4380
     catcgtttgg ataggcggca tttgtaaacc attcaacctc gtaggtccta aaataccaga      4440
     aaaaaagaaa ggaaatttat tgtattgttg taaagccata ttatataagt ttttatgttg      4500
     tgagggtttc aaaaagtcat aaaacaacgt gtttttatta tcatgcaaaa gtcgttcttt      4560
     aaagttactc agaaatattc aaaataatca aatttaagta ttatatttct ttttttatgg      4620
     gaaaatggta acaatagtaa cgataatagg cctgctattt tttgtatgag aagggggtta      4680
     aaggatactt ggattctgta tgtgttgctg ccacttatcc taactaagtt ccgggaagaa      4740
     gccggacaat aactgaacat tagctataat tatttatttg tttgtttatt agtttgtaaa      4800
     aaaaaaaaaa aaaattatct taagcattag gcaaaaaaga ttattttcat agatactgaa      4860
     tttaacgtgc gttttatgct caacacatta tttgattcag catcatcatt tcaatgacaa      4920
     caatgcgtga atagaaataa aacagtgact attttagcta tttcaaataa tatacttagc      4980
     tcatttcttg tcaaggaatt cttgtccttg aagaataaca aaacgttcaa ctgtttagtg      5040
     cctcagtatt ggtatttgga atgttaagac tgtcttaaaa aaatcttctg atgtacgttt      5100
     ataaaccatt agaaggatcc tctatcgagc taaacattat tgtatggaca atcgaacgta      5160
     agaatgccaa gcgcaactct tttgtcccct gtagcaagaa cttgctcaca tcatgattat      5220
     aaaaaaaaca aaaaatggga ttaggaaatt atgaaggatc tgctaaaatc ttgcgcattg      5280
     atctacgtat cgcgggaaaa gaagaattgt tctgcaaagc gtgaatagcc tgatattccc      5340
     agttttctaa cgtcttttga gcagcttcct tctttaatga atttgtatat gattgggata      5400
     aagacgctgt tctcgtagaa aacgtcgacg aagaactagt tgttgacata ctttaataaa      5460
     tattccgaat ggacacaacc ttgaagactt gccaattcga atttctctga ttttactgat      5520
     tcttgctgta aaaagtctta aaaaattcca ataagctata acacgcttga ttgttcaagc      5580
     aaaggatttg agttatttgt agaaatagaa atgtgcttac tcgccatagt tatgaacatc      5640
     gccatgttag tctaggtctc gaagagaaat cgttatttca tgttacgtat aacatcaaag      5700
     ttcgttattg attatttctt atatcattac atcatatacc tttgtaatgc ttaactgtaa      5760
     agtaagctta tttacagtac gaagcagtta gcaaaagaga agtacatttt tataaaatca      5820
     atcatgcgta aatggattaa attcgggttt cacagtaata atttatcatt ttttgaagct      5880
     ctaaccccta cggttcaact atttacaatc taatctcgac cttaaaaaaa caaatatgcc      5940
     tcaataaaaa aaaaaaattt cttacattta gccggttttt atttttaaag ataaatagta      6000
     tcaatattaa aagcacttga ttgcgagaca tgaattacaa aatgtataat attcaatttc      6060
     attagctcgt atagcgattt tgcgtttaag aaacttcgaa aaggtttttt taaaaaaatt      6120
     aaaataaaaa caaagaaaaa tcaaataagc tcatcagttg caatcgggta ttaaaaatag      6180
     agcaacaagt taaaatgaag gaataaaagc aaattactca ttaggtaagg gatccaaact      6240
     caacaaaaag aaaattaaaa ctactaaaat acaaaccaaa aacaaaaaag tcaaatatgc      6300
     acaacgaata cagacattag gtgcttctca aacgagaaag attcacgtta ccaccccttg      6360
     cctcaaggag cttctgataa tttaatagac taatcgtgat tgcaggattt ccatcgggtt      6420
     gttgagcttc atagtttagc aaaagctcga tcgccttcat agcgtcttta gtggtaatct      6480
     ggaattcagt agattcttct tcgtccgtct cgaaagcgcg atcatccatg tactgcgaag      6540
     caatttgatt gattatatcc tcagaggaat caacaatatt ctcttctgaa ggacttataa      6600
     aatcctctat acgcatagca gcttgaacag aaaactctga gacgagctca cgaagtggat      6660
     gaatcatttc atccaaggca cgcgaggtaa cggcagattc attgaataga ccaagaacac      6720
     cggaaagatt gaaggcattt tcaataattt ctggtgatat gtctgtcgtc catgctttca      6780
     ccaaccataa aatagctctt aaaacattag tagtattata gggattgcgt cccaactcat      6840
     tttgttccaa tatatattga acccagtgtt tgcgatagca tgcttttaga gcatagatca      6900
     caccctcact acaaggctgg gaaatagagg ctgaagtaga tggtaaagta attacagttg      6960
     tatttctgag gtcattacca gagtttcgaa tgttttcaac agcacgcaaa tgtggagtat      7020
     agctatcaat aagaagtatg actttgcgac cttccataca cgcatcaaac caacgtagcc      7080
     attcctccat tatagctgtg gtcatggatg ccttaccatt acttctccat ttgaaattca      7140
     ttacttcggg ttttacatta gcagcccgaa acactctggg agattgtgag tatccaataa      7200
     cccataaagg caaacgttcg gttcccgaag cattacaaca cacggttagt gtaatacgag      7260
     ctttgaatcg agtaatacct tttatatctt cgacttcggg agtgccattt ggaaccaatt      7320
     tccaaaaaag accggtctct tgcattgtga agatatcatt aatattcgtt aatcgcgtga      7380
     catcgtaaac acgagagaga ggatcattag gtggttccgt attattcaaa accacagact      7440
     cggtgggttg ttcattaatt gcatgaagta tatggcgctt cctgaaacct tccaaccatc      7500
     cattgctaaa gttcggaacc ggttgatctt gatactcggg aattttgtgc caaagaatag      7560
     cggcggctct cttaattgtt tcaccggaaa gtgtagcatc gtcaccctgt tgaacttgcc      7620
     attcaaataa agcggcctct aaaagagggt atttcggtgg tctgttacgt ttcacgtccc      7680
     atggtttttc tacagtattg tccagatacg agtatttgga ggataagatc tgagagacgg      7740
     aaggctgtga aatatctttg ccaaactttt cacggaacca ttcgataaga tcttgttgac      7800
     cggaacggtt ttgaagttga aaaaagtagt gcctaagagc gcgtttttca tgttctgtaa      7860
     tggctcttct tttgattttt cccattactc gatagcttta ttatttctaa tgtcttgaag      7920
     tgaaaatata aggatagcag agcaaaggtt tcttgcctta ataaaacgac actaacagtc      7980
     acgagttcgt aatattatac tgaacagcgt aacgtaatat ctaagcttaa tatctgttaa      8040
     gcgatgaaac aaacagcggt aaacagtata gtgagtttca tcttcaaaaa tcaacatatg      8100
     gtcgtaccag gtttggcttt cctaattcat ctgggccaat tttttgcagt ggtataaaaa      8160
     aatgaattat tcctggtgct atttcatggt ttccaaataa aagtttttgg tcgacataaa      8220
     ctggattacc agtaagagta ttgttagttt tgtatttagt atatttgtga aattgcgtaa      8280
     aattgctcaa taatagtgcg atgaaggaaa aatggaacaa ggaattaaaa aaaaaataat      8340
     tccgctcagg ggacgaaggg actaaattat ggaaaaagta gtaacaattg attattgatg      8400
     gggttactat aaaatattaa aaaaaaaggt caaactctat aaatgatgta tttaaattta      8460
     tttttattct cttttttttt tttttttttt ttaattttta tattcttcag taaaaactaa      8520
     taatttttgc taggattgca ttcaagtcaa tctaaaaaaa agcaatttgt gtagcaattc      8580
     acatattttt ttacaattga cggtatcatg aattttactg taacttacta actgataaat      8640
     tttctttatt tcgtggatat atactagtct acagaacatg aacatatatg gaagacagta      8700
     gatgaacgaa cattctacac ttacaaacgg acagttagtt atcgccttgg aaattcaact      8760
     tgctaataaa attatattaa atgatatgca tatttaattc cattttccga aatcatattt      8820
     tcttcaaaaa atagcattca aacgcctcaa actcattatc actccattct taattgccaa      8880
     cctatattac caaatgccga tggtgcacat tgccagataa tcggttatta gatccgggtc      8940
     tagagaacga aaccattgca gttgttaaaa tagcatatct tcacaagcca ttgtaaaata      9000
     aaaatatcaa gatatcagat attcattaac ggtgtatcaa gaaatttgag cgcagttaac      9060
     ttacagaacc tcaagtagat aggtatcggt cgcatacctt atctttcgtc ctagttcact      9120
     tgcgaatgtt catactacat gacgccagtc taattactac ttattcatcc ccgtttgtaa      9180
     ataacgactc ggtaaatgct acctcggtta attggacttt gtaaatgtta acagacttag      9240
     cgcgacaaac ctttgagcgg cagcatggta tagcagagga tgaagtgaaa attgggttgt      9300
     tttaatcaga attcaaaaag tatggttttc tatgtaggat cctgaagaaa actgcttgga      9360
     ctccttagtg gcagagcaga tgacaatgaa aaagaaagtc tttttttttt tttaattttc      9420
     ttttcgaatc ctttctttct catttattta tttatttttt tgatatgtct tgtgccccac      9480
     taattgaacg gccacagcag tgtgacgagg taaattagat cgaaatagta tacattttaa      9540
     ggacctgctg atgaagtaaa taaaaagggt tgatatcgtt aaattggtaa gtcacatgtt      9600
     ggtttccgac attgagttga gaagaatcat gtaaacatta ccaaattcat taccgaaaca      9660
     atatgaatta aataaataaa taaataatat ttagagttca atccagccga attggcattt      9720
     ttttacttag caactaactg tctcaaacgc accctggcag caaaggcgtg aaggtagaga      9780
     gcgtgtacaa atgctaatgt tttgtcggct ttttacagcg cttcgttgct atttacaatg      9840
     aatccagcgc gttgtttacg gtataacgac gcggtaagcc acaataaacg gtcgattgct      9900
     acctctcgtc caatctacct ggtaaccgct acctaaatgt aaacaaaaca gtacgcaaat      9960
     ccaagcagta aacaataaaa ccagccatta ggttagccaa ttaaggagtc aaaaagtgtc     10020
     catatttgtc gatcattgtt tacttggtag tgattggttg tcaaattttc tttatcgtag     10080
     catactctag agcgctccgt gagttgagaa attggtataa aagatactca tgcccagttc     10140
     ctttgttcca ttgtttaatt caaagacgaa agctctaatt tagatatcct ttcttttctt     10200
     tctttacctt tttctttctt tttattttta gaagtcgctt gcattttcta ttttacacac     10260
     tttcctttac atacagcccg attatctgtt ttcttcgtta acattgttat cgtgagtttc     10320
     agtttttctt cctttttttt tttttgctgt ctgtatcgat atccttttta aaaggaactt     10380
     cttttttttg aatcggccaa tcactctgtc caattgtaca ttgctatttt gtgtggaact     10440
     gtttttgtac ttcctttgtt cttacattgc gcggtccata aaggtgctca tatatatacc     10500
     ccttttcttt atacctattc tctcttctgc tttgaagaac acataaatat atacacactc     10560
     acttgctttt ctcttagaat ttgagacgtg cttttgaatt gaactaaact ggtttcttaa     10620
     cagtttttcg ttctcttatt cgttctttat atctatattc tatctcttta taatatcatt     10680
     aaaatgctct cttttacatc ggttttttct tttttcttgc atgcattgct tctcaagaca     10740
     gcattttcct atgtaatcaa gcgaaataac cccgtttttg actatacctc ggaaaaagtc     10800
     cgtggtgtaa acattggtgg ctggttggtg ctggaaaatt ggatcactcc acaattgttt     10860
     actcaattta gcagtatgtc gaatcctccc actgatgaat ggggcttttg tgaggttctt     10920
     ggtgcagatg aagctgcctc tcaattagct gctcattata gctcattcta cactgaatct     10980
     gatttcgcta ctatagcttc ttggggtgtt aatgttttgc gtattcctat tgggtattgg     11040
     gcctttaatg tggtagacgg cgaaccatat gttcaagggc aagagtactg gctcgatcaa     11100
     gctcttactt gggctgaaca atatggcctt aaggtttgga ttgacttgca tggtgttcca     11160
     ggcagccaaa atggatttga aaactctggt aagactggtt ccattggatg gcagcaaaat     11220
     gacactgtaa ctcgtactct tgacattatt acctatgttg ctaataagta tacccaatct     11280
     caatatgcca gcgtggttat tggaattgag acggtaaatg agcctttggg ctatggtctg     11340
     gatatggatc aacttaagca atacgattta gatgcctata atatcgtcaa tcctctttcc     11400
     agctctgttg ctactatcat tcacgatgcc tatgttgatc tttctatttg ggattatggt     11460
     gttgtatctc cttcttcata caatcttgtt atggatgtcc atcgttatca actttacgag     11520
     tcggatgagt gctcaaagac tctcgatgat catctttcag atgtttgctc cattggtgat     11580
     tccattgctt cctctcccta cattactgtt actggcgaat ggtccggaac tttagcagac     11640
     tgcacgattt tcgaagaagg agttgactct tcgacattta ttggaccaaa cagcggtgat     11700
     atttccactt ggacggatga atataaggga gctgttcgtc tgtttatcga aactcagtta     11760
     gatcaatttg aacgcggtgc tggttggatt tactggactg ctaaaactgg tggaccaagt     11820
     cctacttggg atatgggatt acttattgaa tacggcgtat tccctcaacc tttcactgat     11880
     agacaatata gctcttactg cggttaagca aagccatatc aaagttaaaa aaaaatttta     11940
     tctattctag ctgtataaca ctaatttata tctcacacat cgttgtcatg tcctgtcctt     12000
     gcatttatca tctactatca tttaacgtgc tgctatctac tatccattca gtctttgttt     12060
     gtttggcatt atctttagac attagttttt aatatatatt gttgttttcg aaatctttta     12120
     gttatgtgat attaatattt tggtagcaag ttcctactaa attaatattt agcttaatag     12180
     tttacgttca atattgcata ttttttcgaa ctctatatta acagtagctg tactttggag     12240
     aaagttgacc gagaaatctt tttaaagttg tccaattgaa ttttcaatta tcaagtatct     12300
     tcagtttact tatatgaaat gtattttctg ctctactctt ataagtcagt attgagccac     12360
     atagacggac cactttgagt tagtctcgga aaagcaaatc gacagaatag gttttcactc     12420
     agccacaggt gacatatgtt taaaatactt ttataaaaat tacatttaaa ttgagcgatt     12480
     tcttggtaaa gtaatattac acattttctg atctgatata ggctttatac gcattaaacg     12540
     aaataagctc attaagcatt ctttaacgaa ctcgcttttt taatttaatg agatatctaa     12600
     ttcactagta tgtattcatt atgttgtccc taacaagatc aaaattgtta cactgtaaat     12660
     gtaacgtagt ttgtcgacta atttatacga ataatagctt tcttcttgcc caaattagtg     12720
     aaatttgtta gacaatttaa acaattaaaa tcatatacag aattaaattg actaattcta     12780
     tttaatcgag agtaacttaa gtattgttcg tcgagcgtat ataccagctg ctacttattg     12840
     cccttgtgga ggaggacatt actgtaattt accgtgtttt agcacattaa accttttaag     12900
     gatgtctgtt taactaacgg ttacggatgt ttaaggagta aaaagtcgag tctgcaaaat     12960
     aactgtaacc tgacctacta gatgatcgag caattgttga gtagttagta tatagtaatc     13020
     acatatgctc cccaatggaa tatcaaagag ccattgattc tattgaagaa tgtctcaata     13080
     aacagttaag actgtcatcc gaaaaggttg accaatatgt actaatagaa aactggacct     13140
     cattagtagg ccacttgaaa accttacact ctttaatatc aaattacaca aatggtagag     13200
     aattacaaaa tgaaattagt tctttgctga agcaggataa ggaactggat ttacaaattc     13260
     aagactgcat gagagaaatg acctcaattt atgataccca tcttccaaaa acagtgtcgg     13320
     ggagaaaacg acaaaaagtt aatgctgaaa cactccttga ttatggtaga aaactttcca     13380
     agttttcctc tgcacctcct gggtacaatc ccgagacggg tcaagatgca aaagctcctg     13440
     tgcattatcc ttggccatcg gaggaccaga tgcgaaaaac tctgttgttt cagttttcaa     13500
     ctagcatggt tccaaattta tcggctacag cgtcccaatt attttctgaa cagcctccaa     13560
     agacgaacga gccaacggaa acagaaacag aaattgatgc gaacaaagcc gttgaagaaa     13620
     aaactaaaat gaattatcct gcctctccaa cattcactac gcaagaggaa aataaagaag     13680
     tagaatcgcc agctaataag gatgtctttg caggatttga tctttttgat ccagaaatgg     13740
     aagaagattt ttgattctaa attgtgttat ttgtcaagtg atatctggta ttttactttt     13800
     ctaattatag agttttttgc tttgaccaaa tacccttttg ttttaaaaat gaataaaatt     13860
     acgctttgcc gtttagactg tatttattta gctttcagac ttcgcaaagc aagatgattg     13920
     aacactgttc cttgcttaac atttgtcaat tcaaatttaa ttaattttaa gtataatttt     13980
     cgaacaatct acgttttctg agttcattta attatgcgtt agcatgaaaa aattcctttt     14040
     ctgcgtgatc attccttgct atgggcataa ggctctctat tacagaaaaa ccgaacgatg     14100
     ggtctttttt aaggactaaa gttgatgatg catgaatgat ataaccttta atatatcctt     14160
     ggtcaattag agaaacacag atacattcga catcgtccat gtcatatgag ttatcatttg     14220
     tacttaaacg ggccgcggtt aacaagtaag aaccagatac gtgcggggtt ttttggcttt     14280
     gctcaaaagt aaaaagaaac ctttttaaat tagtcgaata ttttaaaaaa tctcaaacgt     14340
     acacctttct aaataaattc ctccacagga tgatttcaca tctatccaat aaagttagat     14400
     atattcctcg tttgataaac catttcctcc tggaattgtc ctccaaagat aatctgaacg     14460
     acttgatatc accacttttc aaagctttta ttaaaggttc gaatgctgca gtcaatttgt     14520
     atttttctaa tagccctttt gttggcgatt ttcctaatat aagtaaacac gttgtaagat     14580
     agattagaga aagccttttt tgattagtaa atataaacga atcctatttt tgagtaaaat     14640
     aaaacatacc ttttttgatg ataacactca tcagggcact gaagaaacga aaaaagtaga     14700
     tggtcctttg cctgatgaat tttgcgttga taaagatgac accttcctaa ataataacga     14760
     aacgttacta attccgccat tgtagcgcga gaaatatcgg cacccgaaga gatgacatta     14820
     gcttgaatag tttggcaaag acgaatttgc tttaagcgaa aatatagtaa acaaagtaaa     14880
     ttggcaatac agaatatcgc atccttcttc gaagggttaa tgttttgttg acgatcactc     14940
     agtatactat tgaacgttcg taagacgttc ctagatgcat cgctcacgta tttcctctgt     15000
     atgaacccat taccatcaaa agaatcttct aaagtaggtg tagatgtatc tagctgaagg     15060
     gagagcttta cataaagctt tgaaacgcgt tttacaattg tacacaacca tgctccatcg     15120
     atatgggaga agcaagttgt caagttacta gaaaaacaaa agtgagaaat aataaacaaa     15180
     aagtttttaa ttacctatac aagttttgta acaattccca ttttcgttga tcaggagaag     15240
     atgcagcatt ttcaacgtac tcaaaatagg tagttaccaa ttccttccaa cctcttattc     15300
     ttccaaattc tttttgaatg gttccgttta acttattttt cccctttcta tcctttatca     15360
     cggttagtta atgttataac ctgaagacaa ttacttgtag tgcaagcctg cgacatacca     15420
     aaaaaagagt tttactgagc tgttgaaacg agggctctga tggatctaaa ataatacatt     15480
     tctccaacgt attggagttt ttctctccaa cagcgttact caaagtttgc agaaagtcat     15540
     ttaaggacat tccaacctgt tccttcgcaa cttttagtac taaactttca attattatgt     15600
     aacgataaat aagttataac aagaaaactc aacagatatg ttttcgctta catcgatgtt     15660
     ctccaactct cacgttctga acctcatata cgaataacga aagttagcag gtcgtaaacc     15720
     ggtatacgag gattgttaat agcacaataa agagacatac taagagtaca gcagcattcc     15780
     tcaaattaaa tgctaccagc atcaatcccc aaaaccgtag cactttatat tgatttagtc     15840
     ttaatcatct cggtttgaaa agattctgtt tcgagtcttt gccaagaatt agggaaatag     15900
     taaaatatgc ttttacctag tattccctcg tgttcattta gctttgttgt tttcgtttcc     15960
     gttcttctcc aaacctgttt tagttttcaa ttaactccct taagtccgaa aaactatcct     16020
     cccggtgctt caattgatac aactgtcaat accatttcac catttattgg agatggacgg     16080
     ggttctgaca tctttaatta tgaatgtacg tggttgatag ctcacatgaa ggttcatgtg     16140
     tttttttaaa aactttacaa ttttaaatta ggaaaacact atagaaatat gatttaatga     16200
     aggatataac attttctctc gaactttttt gcttgttact aacttcactt tagactacga     16260
     tgagcgtttc cacttctgtc gaccagagaa tatcgcaaaa caatctgagt cacttggaag     16320
     tgtgcttttt ggcgaccgtc tctacaactc tcccattgaa ataaaaatgc ttgaaaacca     16380
     ggattgtgtt cccttgtgtg cctcgataat tcccagttca gatgtcagtt ttattagaga     16440
     tttaatctcc aaaaactacg ttgttaactg gaacatagat aatctgcccg tagcaacata     16500
     tttagaaggg actaactcaa agaactactc attatcgcca ggctttccat taggcaagaa     16560
     tacggagaag ggagtaattc tattcaatca ttatgatata gttatagaat atcatacgac     16620
     atctagtgac caacaccgtg ttgtgggtgc ttatgtaaaa cctgtctcaa aggagtctac     16680
     tttagttgat ggaaacccag tttgttcttc gtcttcaaat ccacagtatt taccggaagg     16740
     agctgatctt actctcgtga cctcttactc agtctcttgg aaatattccg atactccatg     16800
     ggctacccga tgggacaaat atatgcacat tgaatctagg caaattcgat ggatctttat     16860
     tatccattcc gcaattattg acacatttct aatttttgtg gtttctatta ttttgtacag     16920
     aacgctaaat cgtgacatta ataaatataa tagcgccttt gtcgatcaag aagatgttca     16980
     agaagatttt ggttggaagc tagttcatgg tgatgtattt cgtccacctc gtagacccat     17040
     gctattttct atccttttag ggactggtgc acaacttctt tttatgagct ctggtatcgt     17100
     tttatttgca atttttggca ttgttgcacc ctctcgtcgt ggaagtttag ctacagcaac     17160
     ggtggcctta ttcattatat caggtttcgt ttctggttat gtatctgcat tatcctacaa     17220
     actgatgcaa ggtatgctta gaaagcgaaa tcttctgtta actccttttg tcgtacctgg     17280
     ttttatgctt gcggcagctc ttttctttaa catggtattt tggagtaaaa gttcatcatc     17340
     aactgtaccc ttttcaagct ggcttctact cattttcctg tatctattgt ttactgtacc     17400
     attaagcttt gtcggttctt taatcggctt tcgttctcga gagttcgtcc cacctgttag     17460
     gacaaaccaa atccctcgtc aaattccatc tcatagtatt tggctttcga gttttcctag     17520
     tgcgattatc ggtggatcta taccattcct cgtaatcctt attgaattgt tttctatcct     17580
     tgacagttta tggtttcacc cattgtattt catgttcggt ttctcgttct tttgcttcgg     17640
     tattttagta accacttgta tcatggtttc cattatcact gtttatttcc aattgtgttc     17700
     cgaaaactac aactggtggt ggcgctcttt cataacacct ggattttgtg gaatctatgt     17760
     atttatattt tcagtatttt actggttttt taaaatctca tcatcttccc ttgctactgc     17820
     cgttctttat ttcggctata gtttactgat ttctgttttg gtatttttct tatgtggatc     17880
     ggttggtttc tttggcgcct ttctctttgt taacaaaatt tatgcgtcca ttaaaattga     17940
     ttgattattc gaggcatttg tacatacctc tttatttatt gttcaatttg agctttctcc     18000
     gttacaaacc ttattaatca acaaaatgac ttggagaaca ctctctttta tattcaaata     18060
     atttcatagg aatatgccgt tttttttcgg tcatccaata tataactaca gtttgtttta     18120
     ctttgtgtaa taaaacctta ggtactatat catagaagaa atttgaaaat tgtaatctta     18180
     accaaaatgt ttacttagag taaattaaat ttatgttttc tacgttaaaa gctttattat     18240
     atgttacata aataatacaa aaaaggaata ttactctaac tatatttacg aagctcgccc     18300
     aaaccttttt caactaccag tatttcgcct tcagctcaac cctactttaa aaattgtctt     18360
     tatattactt tttctcagtt taccaaatat ttagaacgta attattaaaa tatcggaagt     18420
     atgccttctt ctgctagtga acaacttctt cgaaaacaac taaaggtaag cgcacgaaat     18480
     cttcatatcc aaatattcat gattgtacat agtatcttaa ttcttgaaca catactgata     18540
     gatataggaa attcaaaaaa atcctccaca gggttttagc gttggtttag tcgatgataa     18600
     atccattttt gaatgggaag ttatgatcat tggaccagaa gatacattat atgaaggtgg     18660
     ttttttccat gcaacattat cgtttcctca agtatgtatt tatgtttcac agaaaaataa     18720
     tatttgttgt ataaggtaaa caagctggtc actaacctcg aaaaattagg attatcctct     18780
     gatgcctcca aagatgaagg tatagtaaat acattgattt tttaattgat agaaactaca     18840
     tagtctatgc ctaaaaacga ttctaacggt aacagttcac aacggaaatt tggcacccta     18900
     atgttcatcc gaatggcgaa gtttgcatat cgattcttca cccaccagga gatgacaagt     18960
     atggatacga ggatgctgga gaacgttggc ttccggtaca ctctccggaa accatattga     19020
     ttagtgtaat ttccatgctt tcttccccta atgatgagtc ccctgccaat atagatgctg     19080
     ccaaggaatt tcgagaaaat cgtgagtata tactaaccta caaacaaaaa aatttactct     19140
     ttaataatca aatcgtacta actttttcca gcacaagaat ttaagaaaag agttcgtcga     19200
     cttgttcgca ggtcaattga aatgatttga agataatgtt caacctaggt ccctaatttc     19260
     ctatatttag aaaaaaggct atgaaggaaa ttcaagtcgc tgcatagaaa acctcctaag     19320
     tcaactagca gtaaagctta ctcaaaaagt ctgtagcttt acaagttgaa ttgcatattt     19380
     tatgccatct ttgaagtatt gccgttgccc attttttgaa taagtttagc aaactgttca     19440
     tttattatca catataatga aatattggca gaacggttga cattttaaaa ctaacagctt     19500
     ttgattcttt tctgttttta ttataaagct ttcaagtttt tcaagtgtta caaccgcaag     19560
     tgatttatcc tacttcttta ccaattacag ccataattta gataaacaac aaataaaaat     19620
     ctacatttca cgattgaatt tttttctttg aacaaacgtc agctaatact tcgtgaattg     19680
     atagttttcc attgaaaatt ttctattcaa gtaattattt tcgcttatac gctcatactt     19740
     tatcagcgac ggtttcaatt ccgcgttttg cacaacatac attgaatgca gcgataaatc     19800
     tcagtctatt atattttaca ctaactagct caatgtctcc tacgtatccg aatgactgat     19860
     tcaatgatta atcaaaccaa ttaaagaatc tagcgaaact tcgttgagtt tgaaaattaa     19920
     atactcagag taaccattta agatgaatat taaaattgca ttaagaaccg tgaaagcatt     19980
     gccttttcat ttagcgtttt tttattgcat tatgcttaaa cttttcagaa tgacaattaa     20040
     tattacgcta ttccgcagta tggtggtgtt cacactggtt caaatgcgta tatggaacgt     20100
     agacagctat taggtcaaat cagatattaa tagcttttat cattgtcatt tctcccttaa     20160
     ctatttgcaa gtcgaaaaaa atccaatttt agctcatgca cagcgttctg cagtaaacat     20220
     gcctctggca ttcacaaatc ccggtacacc tctaaaacgt acagctgcct acgacaatgt     20280
     acaatggaac caaaatcgaa tattagtaag tgaatggacg caaacgatat gcgtttgtct     20340
     gctagtggtt aaactgcaga acgaaagcag catgtcaaag tattgtttcc aattgaagta     20400
     attgtttaac taaatggtag acatttggaa ctcgctatac cgtattaatt attgtaaata     20460
     actacgaatc ttatcaaaat atacaatttg gagagtctat tggtgcagtg gctttggacc     20520
     aacgtacggg gtttctagca atagcacatg gacaagtttt ggatatttat aagcccgccg     20580
     attctttgaa atggactcat cattacaatt atataactca gctttctgaa gatattactc     20640
     aactatcttg gggatacaat tttgatctgt tgctttgtgc ttcgtcatac actaaactta     20700
     taaatttctc tgaagacaaa cccaggttgg tttggtcgca gaacagaatc tcggattcat     20760
     tccttagtag cactatttct tccgatgctt gttttatagc ttctatcgaa acaaaaaatc     20820
     cacttgctaa agtttggcag cgaacatctc ctcaaggtac agttagctca tgtgatgatt     20880
     tcagctatct tgttcatcct tgtcgcgtaa ggttttccca atggtctaaa caccttcatc     20940
     cggacgccag tggatcgact cccttcctga gtacggtagg ctatgataac gttctaagaa     21000
     tttggcaagt tggtagccga tttggttctc aattaatgca tctttcttgt tttcttaact     21060
     tgagaaaata ctacaaatct gatcaaccac catactgctg ttttattgat aaggacgatt     21120
     ttactatagc attagcacat gctataagtc gccattctgg tcaagtgcat aaggatcgca     21180
     ttttaaatag gcttctggct ttggccagtg gacaaccaca tatatttttg ctatttactt     21240
     ttgaatgttt gtacatattt tctctagtaa ttgaccagga aactttgtca tcttttgagc     21300
     ttattaatca agttccaacg aactttccca aaggcgctct tcaacctgac ggatttatac     21360
     ctatttacag gacctcaaaa cacgaatttt acgattataa catcatttta ttttttcaaa     21420
     attccgcccg tgaatacatg tttagtctta ccgatttctt ttatagtgac tttgagttaa     21480
     gagttagtta cgatttttat ggacatgatt atcccataaa aagcttaaca agaacctcta     21540
     atggtcatgg aattgtatcc cgagatgtta atcgtatctg tatgtttcaa tcatacatat     21600
     cgcaagacgg gaaaaatcag ttaatttgca ggttcagatt attacttgga gaatctgact     21660
     ttatattacc tctttatgct ggtgaatatg cagcagtact caacttaaat tctttaaaat     21720
     tatggcattg caatgaagca attcctccaa cccttctctg tacatgtcgt caagtcccta     21780
     ctagtccgat aataaccttc tttattcttc ctgttcaaaa caacgataat tccgccctat     21840
     gtgctttgac ggaaggaggc catgcctggt tttggagtgt ctctaacgaa gctcatgatg     21900
     gttctgctgt acttcggttt atagatcggg taaattttac aaagaattta aatatcgcat     21960
     cggctgtaga tgtcatgggt tggtcttcta ctttaaattt gagcagttta tcttcatttg     22020
     atcaagaggt atttcaatca atatcaaaag acggtttatt acagacttgg atggcaagag     22080
     tattgggaga cgataaagcg gaaatatcgg aaatttccaa agtgcaaact agcatcaaat     22140
     ctgcaactat gatcaaaggc tcaacatcca agaaagttgc tgttgtatct gagaacaatc     22200
     gtcgactttc aattttcgac acgcgtagtt cagaattctc tgaaaaggaa gaattttcct     22260
     ctgtttttga tgattatgga ccaataaatg acttggattg gacttctact cccaattccc     22320
     attctatctt ggctgttggc tttctacatg atgttattct tttgtgccaa aatcgccgat     22380
     cttatatgaa cgatattcca tgttggtctc gtattcgtag atacaatctt ttagaatata     22440
     caaattcatt aatatctgac tcttcttggt tggataatgg gactttagtt actgccattg     22500
     gtaacggact tttttatttt gataattcac ttcccgaaga tcagtcttta ctgttccctg     22560
     catcattgaa acgttccgca aaaaatattt ttgatcttgc ataccagctt aatggaattt     22620
     taccagtttt tcatcctcaa ttgttgcagc agcttttact tagaaaccaa ccctttctat     22680
     ttactaatat tttgctaagg ttttacttgt gtttgaaaga tgatgtagat atgcattttc     22740
     tcttaaatat ggactgcagt gagttttact gctgtgacga agaaatttct aaagaccttt     22800
     taataaaaag tctcagccaa aattctgcgg aaattctaaa tcctgcggaa ttggattttg     22860
     aagagaccag tgtctcaaag catttaggat tatacattga tgaaatgata aagaagttga     22920
     ctgcattatt aaaagtaaag aaagtcaaaa ccctcactcg atcatctcag tttttacttc     22980
     ttaatttaat cgaggcattc aataaggcaa gagcattgcg agattcattg gacctcaacg     23040
     gaaaaagata ttgcattatg ctaaaccagt acgttttatc aaaacatcaa cgtcaattaa     23100
     caagcttgcc cacccgagag atggcgtggg cttttcatag ctctaacaaa gctgttctgt     23160
     tggaccacac taaaaagctt catggaaaac cattgttatg gaatgctgtt gaagaatatg     23220
     cgataccgtt ttggctaaat gagcagctac tgaaagatgt atttttagag ctgtctcgca     23280
     atcattacgc tgagattgac gataggaacc cagagaatgt tagtttatat cacattgctc     23340
     tacacaaaat aaatgtattt cgtgatcttt ggcgtcttgc tagttggcat aaggaatcag     23400
     ctcgaacggt taagttgctt tcgaatgact tttcaaaaaa gaagtggaaa gtggttgcat     23460
     ccaagaatgc ttttgcactt ttaagcaagc acagatattt ttatgcttct gcattttttc     23520
     ttttggcaga tagttgctat gatgccgcaa aagtatgtat ccgtaattta aaaagcattt     23580
     cattagccat cgcaatgact cgagtctatg aaggcgacga tggtccgacc ttaaagaggc     23640
     taataaacga gtatgtactt cctttggctg tatctcaaaa cgatagatgg ctcaccaatt     23700
     ggagtttcac tattttaaaa caggaaaaaa aggccttgca aagtttggta tctcccattc     23760
     gctcgctggt cagcgataat gactttatac aactttatac atccgataaa aacgaccaag     23820
     aaattcacga aaataaagat tcacaacgaa atagtactaa cgaacccgta cgaaataagt     23880
     ttccgtctga tgatcctgcc ttcattttgt tatatgaatg tttaagatcc agcaacgtgc     23940
     aaattgatga aagtcttgaa tatcgatttg ttttgcataa tgctaatgtg tattgccaat     24000
     taggatgtga cctaatagca cttgggcttt tgcgtaattg gaaattccaa aaaaatcctg     24060
     caactgctca tcttgaaact gaggattata tggtaactga caagcagtct gcagtggaaa     24120
     aaactcacga ctcccccaaa cttggaaaaa ctcttatggg acaagatatc cggccaacac     24180
     cggacgatgt ccccgaattt aatgaatctg cgttcagctt cgagtaatta attaattatc     24240
     gatacgagtt tttaaaaata ctacaaaaaa tcaaatacgg tcaaccctta gtttatcgtg     24300
     tttcaataat gatattaaaa attaatttac tattaaatag catataagaa tacagatgaa     24360
     gttcctcagc gtttcattta cacaattgcg caggacgtaa agagagaatt aaaaatttct     24420
     atacatttcg aaaataaaaa cgtccgcggt ataactcgaa aaaagaaaac aaaaatataa     24480
     atagatagtg cagctcacgg aaacaaaaaa ttagacttgc atatcgtttg ttacattcca     24540
     caacactcaa ggttaaattt tgtttcgaaa ggcaaagtaa atgagggaag gattacaatg     24600
     ggatagacga ccaaaagatt ccaaatcaca ccatcagatg gcaaccacaa tttggtaaag     24660
     ttgcttatga gcgttcaccg cgaagacgac gagccaattg catatccttg ggttgaatag     24720
     ttacacgctt tccgtgaata gcacacaagt tagtgtcttc aaatagagag acaagatagg     24780
     cctcaacagc ttcttggaga gcaccaatgg cagaagactg gaaacgcaag tcagtcttga     24840
     aatcttgggc gatttcacgg accaagcgtt ggaaaggtag cttacgaatc aaaagttcag     24900
     tagacttttg ataacgacga atttcacgaa gagcgactgt accgggacga taacgatgag     24960
     gcttcttaac accaccagta gcgggagcag ccttacgggc agccttagag gcaagttgct     25020
     tacgaggagc cttaccacca gttgatttac gtgcagtttg cttagtacga gccattattt     25080
     tctagtgttc tgataattgc cctgtgtaga taaaaacaaa ttatagggag attacgctgt     25140
     ataaatatgt ccctacatcc aactttgatc acaaccctaa ccctttaatt aaattgacgt     25200
     aagttaatag ggacggcgca ttaatatata ttgtgaaatg ccgcataccc tactagcaat     25260
     agaagcactg tttatagtag taactctatt tcgttaatat taatagtgca atatgtctgg     25320
     ccgtggtaaa ggtggaaaag gtttaggaaa gggtggtgcc aagcgtcacc gtaagatcct     25380
     tcgtgacaat attcaaggta ttactaagcc tgccattcgt cgtcttgctc gtcgtggtgg     25440
     tgttaagcgt atttccgctt tagtttacga agagactcgt gctgtcctca agctcttctt     25500
     ggaaaatgtt attcgtgatg ctgtcaccta tactgagcat gccaagcgta agactgttac     25560
     atctttggat gttgtctact ctttgaagcg tcaaggccgt accatttatg gtttcggtgg     25620
     ttaaattcga tatcaattgc cgactccgaa ttttttgttt cgagtctatc aattttatgt     25680
     gtacactata actattctat atatacatgc caaacgagaa tgtttttcat ctgggcgata     25740
     tcagaagaag cattatcaat ttgctagtgc aattcataga caaaaaggcg tttggtcttt     25800
     gtgagaaatt tttcatatcg cgttgtatca cggctgaata ctccatctga caagaagatg     25860
     aatttttctt cgtggatttg tgattaatac atttattgaa tgaaatgatt aatataatgt     25920
     tcattaaacc cgaatcgtat cgtgatattt ataagtagta caaatatagt aaacgcgcaa     25980
     gtttttcttt aggtaattgt ttgtgcgacc ttaagcaaat taacctagtt gatgcgttac     26040
     actgttcttc gtgtcatctt tctgggtatg gggaaagtgt gtctagtgaa tggggttaaa     26100
     gaaggttatc taagcgacta gttgatagca aacagttgca tagccaggaa gattgtgaat     26160
     tgtacggtac atcgtagttg tgaggtaata cgcaactttc taattgagag atatcaaatt     26220
     gaatcagctc gatcgcatac ttagatactt attaagtgtt gtaatttcgt caaataaaac     26280
     ttttaacaat gtaaaaaagt acgtactttc ttccgctcct tgcttaatac cacaataaat     26340
     gaatttacct aatctgtatc taacaaccac atagtcaacg ggactaacaa attccagtaa     26400
     agtgttaagg ataaaaagct ttcagcaatg agagcgtacg actctttctc taatctgaca     26460
     tgttttcttt tgtgtttata aagcattcgt tttgtattga caaatttttc aattaccttg     26520
     ggtaggtgaa ttatttttgg gcatatgaca tcagaacgcg ttgaacaatt aagttcactt     26580
     tgacaaaaat acagattttt tatcactaca cgtcgtttac tttatatttt acttcatctt     26640
     attacaaggt tactctgtaa ttgtaacgtt tgacgaagcc cataatccaa tcctcttttt     26700
     cgttgcagag gaaaataagg aagagtaagt acgtaaagcc tacgaaaaga aagagaaata     26760
     taaaaaagta tacgtttgtc agtgcaatat tgaatggtaa gtttattaat tgttccactc     26820
     atcgactaaa taataaagta gaaagacgag acatttatgt gtatgctaga acacactgga     26880
     atccatttgt tcacgagttg ttctcgtaat aacataatga ttggtattgc cgtgtgtgaa     26940
     tgccagtgat tattgatgtt tgaaagacta caactgataa aaagatagtt gcactagtga     27000
     taaaagtctg ttgaaattgg tatgctctaa aagtcatttg tacttgagta agcagtcata     27060
     tgcgtgttgg ctatccatct gtttgacttg tttgaaaata atacacatgg gttatgcttt     27120
     tcacaagaaa gtagaataat tgattcctac atctgcatca tccatatcga tcggtaaagt     27180
     atactttatc ctacgaattg gtttcatagt taaatcactc ctctgcttag cagctccgca     27240
     tccccttcgt gtactagcca atctcatcga catcgacaaa ttgacttcac ctgagttaag     27300
     catacttaat tcaacttaac gaagtgcaac ccaccacgac tgacctctgt aatctcggaa     27360
     aacggataag acggttcagt acgttcgcta gtaagaagca tgcatgcaaa ggtacaagag     27420
     caggcttccc atgcaaactg agaaaataat ccctgaagaa ttgctagtaa gccaaattgc     27480
     agcgcctcca aacatccttc tattaaggac cagaaagaat gatgctgatg actaattttt     27540
     gggttatgca agaagcatct ggcattttct ttaacttctc cacgaataag gagaaggtca     27600
     cacgacggaa gcgtggaata atgatgagtt tgatcgtcgg taaactcccc cagagtagcg     27660
     aagatcatcg gcatcgaaag aaagaaggga aggaaaaaaa aaagtaaaaa cgacttgatg     27720
     aattccgtga tcatgtaggg taacggaaga cgagattacc gagtttaagt aagcaatcga     27780
     ggtctgcatt gcgatgccga tatggtgatc gggaacatga agcacttgat tgacttgaac     27840
     atgtagggag gaaatttttt tagcgttttt agacttttca tttagctgct atcttaggag     27900
     tagcgtgaca cggcgcaaac gaaaaacaag acatttgttg taccaaacat cctcaattcc     27960
     atcgcatctc taaagtacga gtaactagag taagatgcaa atcaacgtcg tgatatgacc     28020
     taaaagtatc gtggacttga ttcatccttc aatctcatct ttccccgact ccgcctcttc     28080
     attttgacct cattctatga ttgcttttgg aatgaagctt gcagcgtatt ccttcattag     28140
     tgcgttatga ctaaccgcga tatataaggt gatttaagta ctggaagctc gctttccata     28200
     tgagaggaca gcgtagagcg caagtcgcag attgaaggaa tgtaattggg gttcgcttac     28260
     acattacgcg cttttatttg aaaagaacga atcagcagca ctgccagcgc attctgacat     28320
     ttccatgcta cttcattggc ggcctctgat tggctcaatc aatgtaaaac gacgtcaatt     28380
     gctaaccaat gttgtttgac aagggtggtt ttttcaatca gacgcttgac gtcattcttt     28440
     atatatacat tgcctcgcgc atctttgctg ggtagtatgg acactacaaa caacacatat     28500
     gcaagatcaa tttctagtaa tgggaacgat aactttccca ctccagattg gcaatttaat     28560
     ggatcccaat tgcaacaaaa tcgtaaatcc aaaatgaatg gtcgctctgt gactaatgta     28620
     tttccgaatg cattctcgga tgctgaattc gagcaaatct cgatgcccga actcaattta     28680
     aagcgtttta accctactac gttagaagaa aataactcag atttatctga tatgtcctcc     28740
     tgggactata tgatgaacgt tcccattcgt gtctacaacg atgctgacac aatggacccc     28800
     ttctccctcg acactattcc cgattcctcg atggacatgc catttgatcc cttagcatct     28860
     gactatggta acgctgctaa ctttccaagt gtcccttcgt cccttggcag caatcatcaa     28920
     tttatcacca cacctcctgt caacgggtcg aacgaaccta cctcggctca aacgaatcac     28980
     attattactg ctaacagttc ccccagtgga aatgctggga gtaacgcatc tgcaagcatg     29040
     tccgtccctc ctcctcttac tccatctgct tccaccatta atgaccagcc cttctccaac     29100
     tctttcgatt tacctagtca ggtgattgct gatggcactg gcgcgatttc cgacatcaac     29160
     ggtaatccat ttcccatgaa ttctccacct ttggatatgg aaccgttgcc ctcgatatcc     29220
     atggatgcaa gtgactctgt ctccgaacaa cttgtaaagg acgcctctct tcctagtggt     29280
     cctttttcaa ccgattattt ggagaatgga agtgacttaa aaaggtcact gggtcacaat     29340
     caaaagtcag acagagtctc aaaagatgtc tcacctcaac accaagcaaa tccctctacc     29400
     cttaacaatc ctctcaagac ccaaaatttt gattcctcta agaaccttta taccgacaac     29460
     aaggattcct cccttgtatc tccaacggga cttcaatccc gtatggaaca aaatccggaa     29520
     gtgcgggcgc atcctatgaa ggactcggcg acgagcactg cgttacgccg ttctcatgct     29580
     ctgggagctg ctgctgactc tcttcttcct caagaaaact ccgctcagat atatgatggg     29640
     aaggatgtat ctatggtcaa tgataacatg cactccgatg ttcggcagga cagcttcaat     29700
     aaagaatcta ttaaacaacg catcccttct ttgtctcctc cgataacgcg atcatacaat     29760
     gccaagcatc gcccctcctt ggtgcttggt acgtcggtaa atccacattc actttctcct     29820
     tcacagcctc ctgttgtcgt accttcaaat actacgatca gctcctctcc tccactcact     29880
     tctcctgtta aaacctctgc taatatacct aacttattac cgacttcaga gttagacagt     29940
     tccaacgctc ctcactctca atcggctgct actcatgacc taaatgacgt taagtcgtat     30000
     tacaatacta ggtcttctca ttccgtggta cctaatccaa ccaaccaaaa agtaagcatc     30060
     accggtgctg ctgctgatgg ccccaacgga tctgctcctg ttgacaccac tcctacaaat     30120
     tcttctacta ctgctacggg tgctcagagg aagcgtagga agtttaaatt tggtaaacaa     30180
     attggtccag ttcggtgtac tcttcagaac agagttacag gagaaatttg taacacagtg     30240
     ttttctagga cgtatgattt gatccgtcac caggatacga tacatgctaa gacacgacct     30300
     gtatttcgat gtgagatttg tggcgatcaa cgccatttca gtagacatga tgccttggtt     30360
     aggcatctcc gtgtgaaaca cggtagataa attgaaagga gtctcttctg ccacaaatat     30420
     taaaaaaagg ttattgcatt atctattgtc atttttcacc tcttacgctt cttcattgat     30480
     tccttgttta tgaattttaa aaaaagttgc attttgctaa ttattttcaa gaaaaaaatt     30540
     ggtaccgtta ttatttcaca gcccttttga aagtgctttt tcctttgtct cctttcatgt     30600
     acatttatca tcttaatttt gcctcttcat ttcatcgtat cctcaagctt catgtgtaat     30660
     ttcaaacccc ttctccgtct aacggtttcc ttttttattt tggacggtca taagtgtttt     30720
     tatattttgt tttcattttt attgggattg gttaatattg tttttttttt cttaccaagt     30780
     tactgttaaa tgttaataaa aaattttgtg tgttttcacc ttaaattgaa tacctatcat     30840
     gtaatttgat ttagttttac atacttaaat tttaatatta gtaagtagta tttgtaattt     30900
     agaaatattt tttctgccgg tattaattat tattgttttt cagttatgtt aggtatagac     30960
     gcggcctcta gcaatcaaag acggtggatc aaggtctgta gtaaatcgat caatccatag     31020
     gttacctgtc tctgagatac atatgcgtag tggttgattg acaaacgcgg gagataataa     31080
     tcgaaactca aatcttttca tgttctttga catttgggga taaacagaac gaaagtactc     31140
     taacatacta gtcactagaa gaggacctgg aagaacgaga tttggataat tttcggactt     31200
     tgtagcgtat gtcgcattcc aatggatcat atgagcatta aacattaatg ctgaatagcg     31260
     aaacaccata ataggtgtag gtgtgaatac ccaagagtgt tgtggaatac ttttgctacg     31320
     taaagttttt ggtatagcca gttcttgtcg atttaaatag gctaatgttc tatcttcctc     31380
     gatacataat tgatgctgac tgtcgtaaat ttttcttcga atatatacat gctttgtctg     31440
     tttttctgaa gtaggctttg ttagaaaaga actttttgga agacaagctt caacttcttt     31500
     tgtaattgat ggagatttca cagattcttc ctgaatcaat tcatgacatt ccgaagtttg     31560
     gaaaagatgt aaaggtctat gaaaacgaag gactccatgt aaccatattc ggcgcttaaa     31620
     agaaaaagga ttatttggct ttggggaata aagactttca tatccatctg aattcaaatt     31680
     tgattcagga gatgctaaag agaaaaaaag aaaatggtaa ccaggctgta atgatgttat     31740
     tttagcatcc attgttatgc aactaacagg caaatgacca cttaaagtag cttttaactt     31800
     atcaattggc gcttgagata agaaatcctt taaaacgacc tttgctgaca tcgatgatta     31860
     ctttctgaaa cgctttgcac attgactttt caagtaggca atttatcaat actgaaggtg     31920
     atctattaga aattattata aattagccga agcaattatc cctaagaaga cctcaacttt     31980
     taaaatcgga aaggacaaat ctttgaagca ataagctctt aattttatgg aacctaataa     32040
     ctttaacagc tacacattac taattgcttt tggcacgacc caaattgctt aaggtatacg     32100
     tgtaatgctt gttttatacc gttagtggag acttgacctc ttttagcaat gaagtactag     32160
     caaaatttat gataatcgca catctaataa aagataattt caccaaatga aaaaaaaaac     32220
     cacctaagca attaatatac gatttaagtc acatacattt aaattaagcc cttgttggtg     32280
     aatctttatt aattattaat cgtttatgaa cgctgaagta ccttaacctg ttaattgtaa     32340
     agatcatttc tatataatgt taataggtca tcaatgagcc gctttttcat tttcaaatcg     32400
     aatttgacat tgaggtgttg atttacatct attgaaaatg aaggagcaac cgatttgcct     32460
     atatattttc atgcctcttt ttttgcttgt tttttgtttc atattcatca atgtacaacg     32520
     tgctattgga ttacaacacg ttattatggt aaaccgaacg ataacgagat tcattcgttg     32580
     taaccacata atacaaaaag caactttact gttttgagaa agagcaagca taccatgaac     32640
     tatcttgaag gtacgatcga ttttgcagga caattaaggt gtcaaaagta tatgaactat     32700
     ggtctatgta caagtgctgt atgtcaggga taaaatctca tttatttact aatatatcta     32760
     taggttattt cgtacattta tgggtattta gttcaagatt cttattgtgt gattaaattg     32820
     tttttaattt tagcatcgtt ggtggctctt gtaagctagt ttttttgctt ctagtcatgt     32880
     aatattaaca ttcatttaaa aataggtgtg tcttcctgct tggtctatgt acaacaaaaa     32940
     ccctttaaaa tttcaaaaga aaaaggagta agcgggaaat ggggaatctt tctttacttg     33000
     aatcgcaatc tcgcgaaatt aaagaaccaa aataccaaac aaaagttgct ccggctttat     33060
     agaatacaaa taatctttca ttccaaaagt aatgctaaac atgttttaac aacttttgtc     33120
     cgaaaacctt tttttaaacg cacatttttt gcatatccac aatacacgat cgatagatgg     33180
     atttttccgt gatggttcct caaatcttat tgaacatgac tttcctggta ccaataaaga     33240
     gttacatcct ttacatatgg tgcgctttat atctgggtgt attcgcatta ctgatttttg     33300
     tgaaacatcc ttggctgtag agatatagtg tctcgacaat gtaggttctt gaacgtttct     33360
     aaaaagtaat tgcgaagcct ggtataaata tgataccctt gcatgttggt cctttgactt     33420
     tgtactcatc tcgaccgttt atgtttaaaa cacttgagct attaaaggaa ttgcaaaaca     33480
     gagaacaaac aactttccgt ttttataatg gaatgcaaaa gtcaaaaaaa ttatttttaa     33540
     cttaacaatt taattatgtt tcttataaaa atccttcatt aaattaatta ataaatagtt     33600
     aatgcttgtt gcagtctgat tttaccatag gtcaaatttt taatttgttt ttccacggta     33660
     aactgcgtta tgtaattctt tgtaaaagag tacgataaat ttttaaggct tttggatcaa     33720
     ttataaccga gatataaaga gagcacatat gtttattcaa ttaaaaaaaa atcggtcttg     33780
     agtttcgctt gggtttatat gattaatttc tcttacctat aaatagtgag aaatcatata     33840
     ttcgtaagct attattaata cttgttcttt ttagctgatg atgtggaacg aacaagagcc     33900
     taatattttc atgtatttta atgattttct tgtaaaacag tagctttagt attttctgac     33960
     aaagaacttc tgtttgattg tttacatttt taaatagtga gctaaataat ttagagtcta     34020
     tgctagtcgc gacgcgtcaa acccctgtca aaaccaaaac tcattgtatc gagctcttgc     34080
     atttgttcca acaattactg tttaaaaacc tttattccca aaagaaattg ataggaacaa     34140
     cttaatatgg caaagaaatc tttaatggct gagcctggag atcctattcc acggccacgt     34200
     aaaaagagat atcgtccagg tactacggcg ttaagagaga ttcgaaaata tcaaaggtct     34260
     acagacttat taatacaaag gctcccgttt tcaagaattg tacgagagat atcttcagaa     34320
     tttgtagcca atttttcaac ggatgttggt ttgcgctggc aatctacggc actgcaatgt     34380
     cttcaggaag cggctgaagc gttcttggtt catctatttg aagatacgaa tttatgtgct     34440
     attcatgcta aacgagtgac gattatgcaa cgagacatgc aattagccag gaggattcgt     34500
     ggtgcttgac actatatatt caacaaaaaa aaatagtttt acgcttaatc atattgaaat     34560
     tggaattgct aaggtatgat cagtttaatt gatatcaggt gattttgaga cagatcttta     34620
     gctactcatt ataagactct aagcatgcta tctaccaaag aattattaaa aaaaatgtac     34680
     gaatatgctc ataatgaatg ataaatctca ctcctagtta atgccatgtg agtaccgaag     34740
     caacgcaaat tagatcacgt cttgtttcgc ttcattatta ttcaggctgg aatcctggtc     34800
     atcaatctta tttccatact tccttttact ttttttctct cgctgttttt tcttcttgac     34860
     aatacgttga acttttcttg ctaaaagact atcgttcccg tgtttgaatt catctacttt     34920
     ctccgttaac cgtttccttg caatacaacg attttgttca cgtgaacgtg tgtcttgaga     34980
     tc                                                                    34982
//