ID   SPUNK4     standard; DNA; FUN; 31812 BP.
XX
AC   AL031180;
XX
SV   AL031180.3
XX
DT   04-AUG-1998 (Rel. 56, Created)
DT   23-MAR-2001 (Rel. 67, Last updated, Version 6)
XX
DE   S.pombe chromosome I cosmid c2E11.
XX
KW   alpha-trehalose-phosphate synthase; BRCT domain;
KW   cation-transporting atpase; dipeptidyl aminopeptidase;
KW   dna-directed rna polymerase ii subunit; gtp binding protein;
KW   pheromone response; phosphoprotein; protease;
KW   putative 2-hydroxyacid dehydrogenase; rpb7.
XX
OS   Schizosaccharomyces pombe (fission yeast)
OC   Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes;
OC   Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
XX
RN   [1]
RP   1-31812
RA   Murphy L., Harris D., Barrell B.G., Rajandream M.A., Wood V.;
RT   ;
RL   Submitted (03-AUG-1998) to the EMBL/GenBank/DDBJ databases.
RL   Schizosaccharomyces pombe chromosome I sequencing project, Sanger Centre,
RL   Hinxton Hall, Hinxton, Cambridge CB10 1RQ E-mail: barrell@sanger.ac.uk
XX
DR   GOA; O14072; O14072.
DR   GOA; O14073; O14073.
DR   GOA; O14074; O14074.
DR   GOA; O14075; O14075.
DR   GOA; O14077; O14077.
DR   GOA; O14078; O14078.
DR   GOA; O14079; O14079.
DR   GOA; O14081; O14081.
DR   SPTREMBL; Q9C0U3; Q9C0U3.
DR   SPTREMBL; Q9P803; Q9P803.
DR   SWISS-PROT; O14072; ATC4_SCHPO.
DR   SWISS-PROT; O14073; YEA8_SCHPO.
DR   SWISS-PROT; O14074; YEA9_SCHPO.
DR   SWISS-PROT; O14075; YEAA_SCHPO.
DR   SWISS-PROT; O14076; YEAB_SCHPO.
DR   SWISS-PROT; O14077; YEAC_SCHPO.
DR   SWISS-PROT; O14078; YEAD_SCHPO.
DR   SWISS-PROT; O14079; YEAE_SCHPO.
DR   SWISS-PROT; O14080; YEAF_SCHPO.
DR   SWISS-PROT; O14081; TPSX_SCHPO.
DR   SWISS-PROT; O14082; YEAH_SCHPO.
XX
CC   Notes:
CC   Cosmid c2E11 was found to be chimeric, and was split into UNK4 ans UNK5.
CC   This fragment was generated from the original 3' region.
CC   Details of yeast sequencing at the Sanger Centre are available on
CC   the World Wide Web.
CC   (URL, http://www.sanger.ac.uk/Projects/S_pombe)
CC   Protein coding regions (CDS) have been predicted with the help
CC   of computer analysis using the Genefinder program in PomBase
CC   (an ACEDB database) with additional predictions for the
CC   branch-acceptor sites supplied by the program Sp3splice.
CC   CAUTION: It is possible that for any individual CDS we may have
CC   underestimated or overestimated the number of introns/exons or
CC   we may not have chosen the correct splice donor/acceptor sites.
CC   CDS are numbered using the following system eg SPAC5H10.01c.
CC   SP (S. pombe), A (chromosome 1), c5H10 (cosmid name),
CC   .01 (first CDS), c (complementary strand).
CC   The more significant matches with motifs in the PROSITE
CC   database are also included but some of these may be fortuitous.
CC   The length in codons is given for each CDS.
CC   IMPORTANT: This sequence MAY NOT be the entire insert of
CC   the sequenced clone.  It may be shorter because we only
CC   sequence overlapping sections once, or longer, because we
CC   arrange for a small overlap between neighbouring submissions.
CC   Cosmid c2E11 was found to be chimeric, and was split into UNK4 ans UNK5.
CC   This fragment was generated from the original 3'region.
CC   Cosmid SPACUNK4 is overlapped at its 5' end by cosmid SPAC8F11,
CC   EM:AL109738 and at its 3' end by small insert clone SPAPYUK71,
CC   EM:AL109734.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..31812
FT                   /chromosome="I"
FT                   /db_xref="taxon:4896"
FT                   /organism="Schizosaccharomyces pombe"
FT                   /strain="972h-"
FT                   /clone="cosmid c2E11 -chimeric"
FT                   /map="IL"
FT   CDS             complement(1..426)
FT                   /db_xref="SPTREMBL:Q9P803"
FT                   /label=SPACUNK4.18
FT                   /note="SPACUNK4.18, len:141, SIMILARITY:Streptococcus
FT                   thermophilus., Q56049, epsl., (307 aa), fasta scores: opt:
FT                   115, E():0.47, (33.3% identity in 69 aa)"
FT                   /partial
FT                   /gene="SPACUNK4.18"
FT                   /gene="SPAC8F11.10c"
FT                   /product="putative polysaccharide polymerization protein"
FT                   /protein_id="CAB72353.1"
FT                   /translation="MFANINIRKSVWLFLLAAVSCTLFIYGVTRTDLQTLKNPSSLTSP
FT                   SSSTSVDKKKPLFTKSPRNSASCESTITLQSNLLFTYYKHYFAGIKKVALIGFPDHPNK
FT                   GDSAIYVAEKKLLDALNIEVVYITAQEADYSASELKSI"
FT   misc_feature    1..1741
FT                   /note="nominal overlap with cosmid SPAC8F11, EM:AL109738 S.
FT                   pombe chromosome 1"
FT   CDS             complement(2133..3350)
FT                   /db_xref="SWISS-PROT:O14082"
FT                   /label=SPACUNK4.17
FT                   /note="SPACUNK4.17, len:405, SIMILARITY:Schizosaccharomyces
FT                   pombe, YB64_SCHPO, hypothetical 43.0 kd protein c12c2.04 in
FT                   chromosome ii., (384 aa), fasta scores: opt: 1561, E():0,
FT                   (58.5% identity in 378 aa)"
FT                   /gene="SPACUNK4.17"
FT                   /product="putative sugar oxidoreductase; possible sorbitol
FT                   utilisation"
FT                   /protein_id="CAA20147.1"
FT                   /translation="MQNIKDEAYKTYQNVKDEISSHLPQSAPEPTGPPFKCAIFGCGGI
FT                   NFGTAEGPWNNSQKLELVLGHRLQVVALLSPHKSSHERVLKQKAETEYASSYANTREFY
FT                   SADEYLEYLDSHPEEKPDAYIIGIPPETHGSTQKGADLELAILKRFPDASLFIEKPISA
FT                   APVEDAFAVARRLPSESVISVGYMLRYLKTVQKAKEIIKEKNLKVVSTVAKYNSAYIHN
FT                   SKKFWWIMSESGGPVVEQGTHFCDLSRYFGGDVEIDSIKVNRVEWDDPSGKLNAMPVDE
FT                   KTIPPEERIPRFTAASWKYKDGGVGAFTHNITLQGAKYDTCIEVQADGYYLRIVDLYEE
FT                   PVLYVRSPDSDEEKVYKYPNDDPYYSEFKIFLDAAEGKGDKNLIHSDFLDAVKTYELTK
FT                   AITEAK"
FT   misc_feature    complement(2376..3248)
FT                   /note="Pfam match to entry PF01408 GFO_IDH_MocA,
FT                   Oxidoreductase family, score 1.70, E-value 0.00011"
FT   CDS             4989..5318
FT                   /db_xref="SPTREMBL:Q9C0U3"
FT                   /label=SPACUNK4.19
FT                   /note="SPACUNK4.19, len:114aa"
FT                   /gene="SPACUNK4.19"
FT                   /product="very hypothetical protein"
FT                   /protein_id="CAC34972.1"
FT                   /translation="MGSPSLTKTINASLSLHSITQPITLLKTMHYVLQLTILPSAMQHY
FT                   ATLRNFTHPACSVNKQAEQGKEQQQYAMKSQFQFRSGICSKVRSDELGFKGNSLQLNDL
FT                   PKNPY"
FT   CDS             6620..9454
FT                   /db_xref="GOA:O14081"
FT                   /db_xref="SWISS-PROT:O14081"
FT                   /label=SPACUNK4.16c
FT                   /note="SPACUNK4.16c, len:944,
FT                   SIMILARITY:Schizosaccharomyces pombe, CAB52715, putative
FT                   alpha,alpha-trehalose-phosphate synthase., (891 aa), fasta
FT                   scores: opt: 1938, E():0, (38.0% identity in 850 aa)"
FT                   /product="putative alpha-trehalose-phosphate synthase"
FT                   /gene="SPACUNK4.16c"
FT                   /protein_id="CAA20146.1"
FT                   /translation="MGRILIAHLFLPSSVGFSFDTVPHDEVGSKFMQKEESKDWIADTP
FT                   LDESAIVSEEESDDDSLLSDLPEEIDSTNAQSNIATPSPGTVAAAISGIQPPPKTPSSD
FT                   SPSLENSLSNLNDLFKSRGRHMAFSKNDGTNLSLPPSRHQSPPPSSVLASQRHHRRHDS
FT                   ELEEFARRASRSLSFSMNGTPQRRMTFDAEAWKNVIFKIKPSSFGNASFYNAISAATRS
FT                   KQFDDHLFVGTCGIPTDSLPDSLKERISHDYITEHSSLVVYPTDTDFVGHYNHYCKNIL
FT                   WPTFHYQIPDNPKSKAYEDHSWANYVKVNKAFADTIVDNYEQDDMIWINDYHLLLVPEM
FT                   VRERLPRAKIGFFLHIPFPSSEVFRCLATRQEILKGMLGANILGFQIPEFAYHFLQTCS
FT                   RLVNIDIRKNGVVSFENRQIDVIALPISIDPGFIDRCLASPPVEHWAKVLQDRFRGKHI
FT                   ILSHDKLDPIRGLRSKLISFERFLQKYPEYRENTILLQVAPESLQDSEHLPHISDIVTR
FT                   INSAYSNIASRHVPVILLRQKLGYAQFLALMMISDALIDNSLREGISLTSHQFIYVQRK
FT                   RHRPLILSEFVGSASILNDNAIIVNPWDYSKTAEAFRTALTMSEEECQKRNKAMCNLIL
FT                   RHDAASWAVTFQSLIKESWKEQIDMQRIPAFTAQLIKEPYQNAQKRLILLYFEGTISTW
FT                   GSQYHNVMTSLQRTINLLNMLTSDPKNTVYVFSALSCQELEQLFQRVPKLGIVAENGCF
FT                   VRSPPKGDATMPVSKKEIAELWKNKVLGTDLTWMKTVSEIFEYYAERTTGAYVENKDAT
FT                   VILHLREAEDDEAAMWAAKECCESVNNFNVPCSATIQNDMVVCRSNKVSKRLAAEDIYS
FT                   ANGGDYDFIFAASNDPDDDTVFSWMKNFKQSKKEVVPFTFSVCVSEHGNSTNADAESSG
FT                   VFGFLQALEKVYSA"
FT   misc_feature    7130..8575
FT                   /note="Match to PF00982 TrehaloseP_syn,
FT                   Trehalose-6-phosphate synthase domain Score 879.40"
FT   CDS             complement(10206..10832)
FT                   /db_xref="SWISS-PROT:O14080"
FT                   /label=SPACUNK4.15
FT                   /note="SPACUNK4.15, len:208aa"
FT                   /product="hypothetical protein"
FT                   /gene="SPACUNK4.15"
FT                   /protein_id="CAA20145.1"
FT                   /translation="MPQFFRTQPLTDRTTSHGFAEVSSEDHCYCVWLVPAISSDIELRY
FT                   RTFVDWAVCHKVDFEEMQLPTAPHITLARGIKLKPNQSFKSVLQYIASKRKSPLNIKFG
FT                   KVAIGDSFYKRVYIQVEKTPGLEELQNAAYDLADTSDPFNVIEHPYMPVIYAKSICSDY
FT                   STSDPIETISSIGQASWGKACFLELIQLNKANHQGYVCDRIEFTV"
FT   CDS             join(complement(13941..13955),complement(12643..13884),
FT                   complement(12285..12590))
FT                   /db_xref="GOA:O14079"
FT                   /db_xref="SWISS-PROT:O14079"
FT                   /label=SPACUNK4.14
FT                   /note="SPACUNK4.14, len:520aa"
FT                   /note="SPACUNK4.14, len:520, SIMILARITY:Candida albicans,
FT                   O94002, sec12 homologue., (841 aa), fasta scores: opt: 181,
FT                   E():0.0045, (24.5% identity in 274 aa)"
FT                   /gene="SPACUNK4.14"
FT                   /product="hypothetical BRCT domain containing protein"
FT                   /protein_id="CAA20144.1"
FT                   /translation="MGVMTVPNTPQKPNLQQQKFEAINANEDQIDYSSNLEQNYNSLIR
FT                   QGSDQVIPLSRFASEKSALELEKELFSERIPESQSAAEPVLKVENSENDLDEKLVLDGQ
FT                   HVEGDHSSDTEEEVVSEDQKQLNKTDDESTFIESHQIYIQGETKSPSSVSQSLSGDPSL
FT                   KPAEVFDRKQSAEINSPIEKDVNPQQNISDSSIKNNSIHSDEVNPEVRPDLTPSNENEE
FT                   SKRSAPEIALKEKESTSQDESNREAEEAPISTNYSFPSSSLEDQPDKNVQSSAVENKNK
FT                   HTNLVTSSFNLTKPMKSFIRRNGLRVQESVTDETDFVILGSPPLRRTHKFLLATSLGIP
FT                   LVSSQYLTDCIKSGKVLDFRSYKYKDEEAEAKWGFRLDDIHRRTCFNGKRLYITKAIRD
FT                   SMVGDSIHGLYSILETSGAEIVGDIKRAQEKDTIILAQPDNDQEGRNMSATGLNVYKIE
FT                   LVALSILRDRIDFDEFLIDYDADSPTKVIGKRNVSKASRTGQGRKRSSRSSWNKPSAKE
FT                   QRT"
FT   misc_feature    complement(12591..12611)
FT                   /note="ctaatgatttaaatag, splice branch and acceptor"
FT   misc_feature    complement(12637..12642)
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    complement(12811..13047)
FT                   /note="Match to PF00533 BRCT, BRCA1 C Terminus (BRCT)
FT                   domain Score 40.72"
FT   misc_feature    complement(13885..13901)
FT                   /note="ctaacctattttccaag, splice branch and acceptor"
FT   misc_feature    complement(13935..13940)
FT                   /note="gtatgt, splice donor sequence"
FT   CDS             join(14443..14627,14693..14733,14825..15822)
FT                   /db_xref="GOA:O14078"
FT                   /db_xref="SWISS-PROT:O14078"
FT                   /label=SPACUNK4.13c
FT                   /note="SPACUNK4.13c, len:407, SIMILARITY:Arabidopsis
FT                   thaliana, AAD25745, t5i8.3 protein., (394 aa), fasta
FT                   scores: opt: 1071, E():0, (45.8% identity in 384 aa)"
FT                   /gene="SPACUNK4.13c"
FT                   /product="conserved gtp binding protein"
FT                   /protein_id="CAA20143.1"
FT                   /translation="MRGIVTRIVLSTQKCLPSVNCTRRYYSKQKDISIVRQRLGRPGNH
FT                   LKIGIVGMPNIGKSTLFQILTKTNLGNPANYPFATIDPVHAKAPVLDSQYELLCEIYQP
FT                   KTRIPAQLTIYDTAGLTRNSSKGEGLGNAFLSNIRSVDALFQLVRAFPEAQVPHVEKSV
FT                   DPVRDLQIIQEELLLKDAEFLESYLKKEGRSPKTCAKALDTARRALEVVLGKGRQISKA
FT                   EWNDEQIPILNSLNLLTAKPVVYLVNMDQDDYLSDEQEALKGIKEWVEKNSFGDQVIPL
FT                   SVLFEEQLFMLTPEEAAQECASLGKNSQLSEIICAGYSALNLIHYFTASEKIVQAWTIA
FT                   DGSKAPDAAGIIHSDFKKKFVAGEVIKFSDFEKYKSVDACKSVGKCKTKGKDYTVEPGD
FT                   IIFWKIAR"
FT   misc_feature    14596..14619
FT                   /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
FT   misc_feature    14628..14633
FT                   /note="gtacgt, splice donor sequence"
FT   misc_feature    14677..14692
FT                   /note="ttaacaataaatatag, splice branch and acceptor"
FT   misc_feature    14734..14739
FT                   /note="gtacgt, splice donor sequence"
FT   misc_feature    14804..14824
FT                   /note="ctaacaaaacaaatttataag, splice branch and acceptor"
FT   CDS             16140..19049
FT                   /db_xref="GOA:O14077"
FT                   /db_xref="SWISS-PROT:O14077"
FT                   /label=SPACUNK4.12c
FT                   /note="SPACUNK4.12c, len:969, SIMILARITY:Rattus norvegicus,
FT                   IDE_RAT, insulin-degrading enzyme, (1019 aa), fasta scores:
FT                   opt: 2197, E():0, (37.2% identity in 975 aa)"
FT                   /product="protease, possible pheromone response"
FT                   /gene="SPACUNK4.12c"
FT                   /protein_id="CAA20142.1"
FT                   /translation="MDGKPQVEVIVNGQVVPNLDDREYRLIKLENDLEVLLVRDPETDN
FT                   ASAAIDVHIGSQSNPRELLGLAHFCEHLLFMGTKKYPDENEYRKYLESHNGISNAYTAS
FT                   NNTNYYFEVSHDALYGALDRFAQFFIDPLFLEECKDREIRAVDSEHCKNLQSDSWRFWR
FT                   LYSVLSNPKSVFSKFNTGNIETLGDVPKELGLDVRQELLKFYDKYYSANIMKLVIIGRE
FT                   PLDVLQDWAAELFSPIKNKAVPIPKFPDPPYTDNEVRKICYVKPVKNLRRLDIVFPIPG
FT                   QYHKYKCRPAEYVCHLLGHEGEGSYLAYLKSLGLATSLIAFNVSITEDADIIVVSTFLT
FT                   EEGLTDYQRVIKILFEYIRLLDQTNAHKFLFEETRIMSEAQFKTRQKTPAYQYAHVVAS
FT                   KLQREYPRDKVLYYSSVLTEFDPKGIQEVVESLRPNNFFAILAAHSIEKGLDNKEKFYG
FT                   IDYGLEDLDSQFIDSLLHIKTSSELYLPLANEFIPWSLEVEKQPVTTKLKVPNLVRNDK
FT                   FVRLWHKKDDTFWVPKANVFINFISPIARRSPKVSVSTTLYTRLIEDALGEYSYPASLA
FT                   GLSFSLSPSTRGIILCISGFTDKLHVLLEKVVAMMRDLKVHPQRFEILKNRLEQELKDY
FT                   DALEAYHRSNHVLTWLSEPHSWSNAELREAIKDVQVGDMSDFISDLLKQNFLESLVHGN
FT                   YTEEDAKNLIESAQKLIDPKPVFASQLSRKRAIIVPEGGNYIYKTVVPNKEEKNSAIMY
FT                   NLQISQLDDERSGALTRLARQIMKEPTFSILRTKEQLGYIVFTLVRQVTPFINLNIFVQ
FT                   SERSSTYLESRIRALLDQFKSEFLEMSDEDFSKHKSSLINFMLEKHTNLKEESSMYWLR
FT                   ICDGFYDFTRLEKQAEIVSTITKDEFYSFFINNIHYEGENTKKISVHVVSQRCEDEVYE
FT                   IPNVTIIENGNMFKESMTLSKAAFPLKPFDEIDRSLLFN"
FT   misc_feature    16236..16655
FT                   /note="Pfam match to entry PF00675 Insulinase, Insulinase (
FT                   proteinase M16)"
FT   misc_feature    16302..16373
FT                   /note="PS00143 Insulinase family, zinc-binding region signa
FT                   ture"
FT   CDS             join(19259..19285,19341..19880)
FT                   /db_xref="SWISS-PROT:O14076"
FT                   /label=SPACUNK4.11c
FT                   /note="SPACUNK4.11c, len:188, SIMILARITY:Plasmodium
FT                   falciparum., CAB63561, hypothetical garp protein., (673
FT                   aa), fasta scores: opt: 137, E():0.53, (31.4% identity in
FT                   105 aa)"
FT                   /product="similarity to phosphoproteins"
FT                   /gene="SPACUNK4.11c"
FT                   /protein_id="CAA20141.1"
FT                   /translation="MSSKLLSMKFMQRARGIDPKQAEEELSKNIVTDEHWSLAGKVDFL
FT                   PQKMTRNVEYESGYGGLIEENDLESHSNEPNLVQGRASFGLFNKELGEENVDEKDVSKN
FT                   EEVDVNGTKITDTSELTERERRKQELVSKKAEASRKMEVKAPAKESKKRKVNELSQDVI
FT                   SLHSPKESNARKTKKNKNKKKKKRN"
FT   misc_feature    19286..19291
FT                   /note="gtacga, splice donor sequence"
FT   misc_feature    19323..19340
FT                   /note="ctaacctgtattttgtag, splice branch and acceptor"
FT   misc_feature    complement(20150..21904)
FT                   /note="primary transcript EM_FUN:SPD185, D89185, Fission ye
FT                   ast mRNA"
FT   CDS             join(complement(21533..21628),complement(20411..21276),
FT                   complement(20317..20359))
FT                   /db_xref="GOA:O14075"
FT                   /db_xref="SWISS-PROT:O14075"
FT                   /label=SPACUNK4.10
FT                   /note="SPACUNK4.10, len:334, SIMILARITY:Candida albicans,
FT                   O94020, ynl274c homologue., (342 aa), fasta scores: opt:
FT                   865, E():0, (41.7% identity in 338 aa)"
FT                   /product="putative 2-hydroxyacid dehydrogenase"
FT                   /gene="SPACUNK4.10"
FT                   /protein_id="CAA20140.1"
FT                   /translation="MTLSGKPAALLVGTLKHAHKEWEALGKYAELKTYSDGTREDFLAK
FT                   CKTEFQNVKAICRTYNSKFYMGIFDKEIIDNLPPSVKFICHLGAGYETVDVAACTARGI
FT                   QVSHVPKAVDDATADVGIFLMLGALRGFNQGIFELHKNNWNANCKPSHDPEGKTLGILG
FT                   LGGIGKTMAKRARAFDMKIVYHNRTPLPEEEAEGAEFVSFDDLLAKSDVLSLNLPLNAH
FT                   TRHIIGKPEFQKMKRGIVIVNTARGAVMDEAALVEALDEGIVYSAGLDVFEEEPKIHPG
FT                   LLENEKVILLPHLGTNSLETQYKMECAVLMNVKNGIVNDSLPNLVPEQRGDIE"
FT   misc_feature    complement(20360..20375)
FT                   /note="ctaactttttttctag, splice branch and acceptor"
FT   intron          complement(20360..20410)
FT                   /note="confirmed intron"
FT   misc_feature    complement(20405..20410)
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    complement(20494..21105)
FT                   /note="Match to PF00389 2-Hacid_DH, D-isomer specific
FT                   2-hydroxyacid dehydrogenases Score 236.79"
FT   misc_feature    complement(20620..20670)
FT                   /note="PS00671 D-isomer specific 2-hydroxyacid
FT                   dehydrogenases signature 3"
FT   misc_feature    complement(20689..20757)
FT                   /note="PS00670 D-isomer specific 2-hydroxyacid
FT                   dehydrogenases signature 2"
FT   misc_feature    complement(20815..20898)
FT                   /note="PS00065 D-isomer specific 2-hydroxyacid
FT                   dehydrogenases NAD-binding signature"
FT   misc_feature    complement(20863..20886)
FT                   /note="PS00017 ATP/GTP-binding site motif A (P-loop)"
FT   misc_feature    complement(21277..21291)
FT                   /note="ctaatgtcgttttag, splice branch and acceptor"
FT   intron          complement(21277..21532)
FT                   /note="confirmed intron"
FT   misc_feature    complement(21527..21532)
FT                   /note="gtaaag, splice donor sequence"
FT   CDS             complement(23073..24092)
FT                   /db_xref="GOA:O14074"
FT                   /db_xref="SWISS-PROT:O14074"
FT                   /label=SPACUNK4.09
FT                   /note="SPACUNK4.09, len:339aa"
FT                   /product="hypothetical product"
FT                   /gene="SPACUNK4.09"
FT                   /protein_id="CAA20139.1"
FT                   /translation="MQMNSLNDPKHLVKAVVRGEIKCLDVRAQSKYEISHLRKSVNIPS
FT                   EKISKCWYQLPAKQEELFVVEDQGDKIETEETGTCAQQLKKRGWNIAGHFMFSHKIWED
FT                   LSLPQNELLESGPNRNLLFEPCPYLKEVMPVVEKGIKTNNARVLDIGCGSGRDLAWICF
FT                   RESGKHWMVSALDAEKRAIQRFSELFSGLGLEDRIEGKKVAKVDASGLWKLYTRDGKQE
FT                   PNATAISLADMLADFQNVPEGDVYKYDLVLQIRFLNRALLRQSSSLLRNNGFLFLCTFV
FT                   NDGVHQYEHPRGSDHRFEKGEAAAIVSESDGRIRVLKDEIGFIEDGRPVQILLAQKVE"
FT   CDS             complement(24320..26701)
FT                   /db_xref="GOA:O14073"
FT                   /db_xref="SWISS-PROT:O14073"
FT                   /label=SPACUNK4.08
FT                   /note="SPACUNK4.08, len:793, SIMILARITY:Aspergillus
FT                   oryzae., O42812, prolyl dipeptidyl peptidase precursor,
FT                   (771 aa), fasta scores: opt: 1514, E():0, (35.7% identity
FT                   in 782 aa)"
FT                   /product="dipeptidyl aminopeptidase"
FT                   /gene="SPACUNK4.08"
FT                   /protein_id="CAA20138.1"
FT                   /translation="MNDFSFEDKGLISRSGFGSRHVRRVVKALALIFSLLILYLTISNV
FT                   SDSPPKRDSLSLDDIVLQKYKPSYKQVNWIDSQGLKDTFLVKYGDLINIQDPYNLNKTL
FT                   FSVSDLVYNGIQLDYDSYSISFDAKYVLVSVNKSQRWRHSSFAQYYLYNTETKDVNMLG
FT                   QDNEHWTISLAEWSPTGHQLSFVYNNDLYVRKNDGNVQRLTYDGTVDVFNGLTDWIYEE
FT                   EVLSSPSTIWWSPDSDKIAFLKLNESEIPTYHYPLYTAELDPSLPEFDYNKDMAIKYPK
FT                   PGNPNPSVSLFVADLNSNASSNFSLWHNEPLAEPVVQNVLWVNTSSVLVQFTNRNSTCI
FT                   TARLLDTELKSIHTVKTECLEEGWYEVQQSAKMFPLNNSLVWENWSDGYFDILALDDYN
FT                   HLAFIPFNGSSPIYLTSGAWDVTDGPIHIDGDFGNVYFLATLKDSTERHLYYVSLDTLE
FT                   IYGITDNGEDEGYYSTSFSPFGDFYVLNYHGPDVPWQELRSTKDKDYCLSLETNSRLKQ
FT                   QLSSITLPSVEYGKLTFNDTTFNFMERRPRNFDVNKKYPVLFFAYGGPGSQQVAKLFRV
FT                   DFQAYLASHPDFEFIVVTLDGRGTGFNGNAFRYSVSRHLGEWESYDQGQAGKFWADLPF
FT                   VDENHVGIWGWSYGGYLTLKTLETQDVFSYGMAVAPVTDWRLYDSVYTERYMDLPQYNK
FT                   EGYKNSQIHDYEKFKQLKRFFVAHGTGDDNVHFQHSMHLMDGLNLANCYNYDMAVFPDS
FT                   AHSISYHNASLSIYHRLSEWIGDALGRIDPSTGVRQHRWD"
FT   misc_feature    complement(24746..24838)
FT                   /note="PS00708 Prolyl endopeptidase family serine active si
FT                   te"
FT   misc_feature    complement(24746..24982)
FT                   /note="Match to PF00326 Peptidase_S9, Prolyl oligopeptidase
FT                   family Score 74.59"
FT   misc_feature    complement(24986..26539)
FT                   /note="Match to PF00930 DPPIV_N_term, Dipeptidyl peptidase
FT                   IV (DPP IV) N-terminal region Score 905.74"
FT   misc_feature    complement(25826..25852)
FT                   /note="PS00221 MIP family signature"
FT   CDS             27160..30795
FT                   /db_xref="GOA:O14072"
FT                   /db_xref="SWISS-PROT:O14072"
FT                   /label=SPACUNK4.07c
FT                   /note="SPACUNK4.07c, len:1211, SIMILARITY:Saccharomyces
FT                   cerevisiae, ATC6_YEAST, probable calcium-transporting
FT                   atpase 6, (1215 aa), fasta scores: opt: 3613, E():0, (49.9%
FT                   identity in 1232 aa)"
FT                   /gene="SPAPYUK71.01"
FT                   /gene="SPACUNK4.07c"
FT                   /product="P-type calcium ATPase"
FT                   /protein_id="CAA20137.1"
FT                   /translation="MGSKALITSPDISSGQLYIKLPTFFHLYVWPFALFVYPYIGYVYQ
FT                   NKLYSEEVRYLTYIAVGTIHALFWLAGEWNTKVYCLMTCRKTDKVEQATHILVTPSKIG
FT                   ESSSVEPITKLVLPDSQTIQYSFSFQRKRFIYEPEKGCFANITFPMDEPSTIGTLKKST
FT                   GLTNIQSEIFLYRYGKNCFDIPIPTFGTLFKEHAVAPFFVFQIFCCVLWCLDDYWYFSL
FT                   FSMFMIIALECSVVWQRQRTLTEFRTMSIKPYEIQVYRNKHWFPISTEDLLPNDVVSVL
FT                   HNKEDSGLPCDLLLLSGSCVVNEAMLSGESTPLVKESIELRPEEAVIDVDELDKNAVLF
FT                   GGTRVLQVTQSPFCKLKTPDNGVPAIVLRTGFETSQGSLVRTMVFSSEKVTANNRESLY
FT                   FILFLLVFAIAASGYVWHVGSKTERSRYKLMLDCVMIITSVVPSELPMELSMAVNASLG
FT                   ALSKYYIYCTEPFRIPLSGHLDICCFDKTGTLTEEHMVVQGIAGVNRKDPYSLEKLSDA
FT                   SNDAILAIATAHTLVLLEQEGETPKVVGDPMEKATVENLGWSIEKKNFVSAPEGSVFYK
FT                   GKVQIIRNFQFSSALKRQSSVSNVRVSGGSFKTFVSVKGAPEVIATMLREVPKDYEKIY
FT                   KDYGRKGSRVLALGYKYFKNYIPENQVSDLSRESIESDLVFAGFLIFTSPLKEDARQTV
FT                   QMLNNSSHRCMMITGDNPLTAVYVAEQVGIVEKPTLVLDIKHENEKILEWKSTDDTINL
FT                   PMNPHKSLEASLYEKYDLCITGRALSQIINPDVIMSIFTHAWVYARVSPSQKEFMISTL
FT                   KHNGYITLMCGDGTNDVGALKQAHVGVALLNASEEDMLEMQERARNQKLMGVYEKQIQL
FT                   AKRFNLPTPPVPPALCHAFPPGPNNPHREKTQEGLNKVLEDLETKKASDVQLTEAEKAA
FT                   ERRANLANKMFDTLANASDDEAPKLKLGDASVAAPFTSKLAVVSSITNIVRQGRCTLVA
FT                   LVQMHKILALNCLITAYSLSVLHLDGIKFGDTQYTISGMLMSVCFYCVSRARPLETLSK
FT                   ERPQAGIFNTYIIGSVLGQFAIHIVTLIYITRVVYLYEDPLEKVDLEETFKPSLLNTAI
FT                   YLLQLIQQVSTFAINYQGRPFREALSENKGMYYGLLGIAFVAIAGVTEFSPELNAKLQL
FT                   VKMAYNFQIQLLATMVVDYAACWIIEELMKKYFRDNKPKEIVLRN"
FT   misc_feature    28027..28200
FT                   /note="Pfam match to entry PF00122 E1-E2_ATPase, E1-E2
FT                   ATPase, score 15.00, E-value 0.0018"
FT   misc_feature    28588..28653
FT                   /note="Pfam match to entry PF00122 E1-E2_ATPase, E1-E2
FT                   ATPase, score 15.50, E-value 0.0014"
FT   misc_feature    28612..28632
FT                   /note="PS00154 E1-E2 ATPases phosphorylation site"
FT   misc_feature    29161..29679
FT                   /note="Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 ATPa
FT                   ses"
FT   misc_feature    29623..29691
FT                   /note="PS01229 Hypothetical cof family signature 2"
FT   misc_feature    30422..31812
FT                   /note="nominal overlap with small insert clone SPAPYUK71,
FT                   EM:AL109734 S. pombe chromosome 1"
FT   CDS             31389..31812
FT                   /label=rpb7
FT                   /note="SPACUNK4.06c, len:>141"
FT                   /partial
FT                   /gene="rpb7"
FT                   /gene="SPAPYUK71.02"
FT                   /gene="SPACUNK4.06c"
FT                   /product="DNA-directed RNA polymerase II subunit"
FT                   /protein_id="CAA20136.1"
FT                   /translation="MPFFLKELSLTISLHPSYFGPRMQDYLKAKLLADVEGTCSGQYGY
FT                   IICVLDSNTIDIDKGRVVPGQGFAEFEVKYRAVLWRPFRGEVVDAIVTTVNKMGFFANI
FT                   GPLNVFVSSHLVPPDMKFDPTANPPNYSGEDQVIEKG"
XX
SQ   Sequence 31812 BP; 9791 A; 6013 C; 5966 G; 10042 T; 0 other;
     gatcgacttc aactcagaag cagagtagtc agcctcttga gcagtaatgt agacaacctc        60
     aatattcaaa gcatccaaaa gctttttctc agcaacatag attgcactat cacccttgtt       120
     ggggtggtca ggaaacccaa tgagcgcaac cttcttgatg cctgcaaagt aatgcttgta       180
     ataagtgaag agtaagttgg attgcagagt gatggtggat tcacaggaag cactatttct       240
     gggtgatttg gtgaaaaggg gctttttctt gtcaaccgaa gtagacgagg aaggagaagt       300
     tagactacta gggttcttca aagtttgcaa gtcggtgcgt gtcacgccgt agataaacag       360
     cgtgcaagac acggcagcaa ggagaaaaag ccacacggac tttcgaatat taatgtttgc       420
     gaacattttg agttgagaaa aaaaaagaaa ggaagaaaaa cgatagaata aaagaacgac       480
     acacgtctat cgtcgtaaaa atttttaatg acaggagaaa ttaaattcga taatcccgga       540
     acaataatta gcgaggtgtg agtattaagt tggataggat aatgattatc aaactaaatt       600
     tagaaaaaaa aaaattagca tttgatcgac aaaaaatttc aatgtagtca aattacacca       660
     aataataaca cttaccaatt atttaaccaa gtgtattata aattaggaga aggaatcttc       720
     gcagcaccgt ttggtgtagt gtttggttaa aggcaacctc taaatgctag gacgcaaagg       780
     gtaatttcga ataccgtgtg ctatcaccaa acttttcaat tcgtaaagcc gagctagtat       840
     gactctagaa gtaatttaca ccacactttc ttcttttact ggtggccggg cttcaatttt       900
     gacattttta tttcacgtta cagcttacat ctaattgcga ttttccgagg cgtttgcgtt       960
     tccgatgatc agatctgata gaaggtgaaa aactttccat cccaacgata atagaggagg      1020
     ttaacgcaca tagactcttt acgttatatt ctcatatcaa atatgaaatt ttttatgaga      1080
     atatgtaaag tctttgctcc tttctcaatg tttacaaaaa taattttatc gagagatttt      1140
     tcaataaatt acctggatag aatattcatt gttaggtgca ccccggaagg cttttgccga      1200
     aaactccgcc tcaagttata cgccccgtca tcttttaaac tcagacaatg tccactccga      1260
     ccataaagtt tgctgtttac atgtcagcta agaaaatggt aggagcgcct ttgttgggct      1320
     cgtaagtgtc aattgtaaac aatgaccaga caataaacaa agaaagagtc tcttttacaa      1380
     tcataagtac gtgcctgaat gctttgtttt ctctactgtg ttgggtactt gtttacaatt      1440
     tggcatggca ggttgagctt gcaatttgca ggggttaaag caaaccatgc ctgcgtacaa      1500
     aggtggtagg catatcaacc tgtgttggga tacggtgagg agcacagtag tgggaaggag      1560
     aaaaattctc aaagcaaaat catgccctga gtatgaaaat tgctgagaaa gttgttgttg      1620
     tttgattttg gagatatggt agacgcaaat tacgcttgct attactagaa ttaactagcc      1680
     tgtacttatt gaatgatcaa gattactttg acactttgtg tttacaacat gtttgttagc      1740
     ttttttgcta ctaaattaat ttggctaaaa acaaaatgtt ccactttgaa atcttttccc      1800
     tcgatactta tttatttgtt gatcactctt gtttacatcc gtatttccta catacacttt      1860
     aattcccttc ccgcataatc tatgcaaaca aaaaaaaaat tatttattca ttctaatccg      1920
     cgttctgcgg cacccattgt aataaaatca taatcaacat tataccaaat catcatgggt      1980
     atcttttcaa ggcatgacta aactatttag agtatccata taccatacat atttccttaa      2040
     acaaacaaac attttatatg caaaattgac ataaacttga tttctttttc tcttgcaaac      2100
     ttggaaatca ccgtcccaaa aaaataaaac acctacttgg cttcagtgat ggccttggta      2160
     agctcatagg tcttgacggc atccaaaaag tcggaatgga taaggttctt gtcaccctta      2220
     ccttcagcag catccaagaa gatcttgaac tcactgtagt atgggtcatc attggggtat      2280
     ttgtaaacct tttcttcgtc cgaatcagga gagcgaacat acaagacggg ctcttcataa      2340
     agatcaacga tacgaaggta gtaaccatca gcctgaactt caatgcaagt atcatacttg      2400
     gcaccttgaa gagtaatgtt gtgagtaaaa gcaccaacac caccgtcctt gtacttccat      2460
     gaggcagcgg taaagcgggg aatacgctcc tctggaggaa ttgtcttctc atcaactggc      2520
     atagcattta atttgccgct agggtcatcc cactcaacac ggttgacctt gatactatca      2580
     atctcaacat caccaccaaa gtagcgagag agatcacaaa agtgggtacc ttgctcgacg      2640
     actggaccac cagactcaga catgatccac cagaacttct tcgagttgtg aatgtaggca      2700
     gagttgtact tggctacagt actgacaacc ttcaagttct tttccttgat tatctccttg      2760
     gccttttgaa ctgtcttcaa ataacgaagc atgtagccga cagagataac ggattcagag      2820
     ggcaaacgac gggcgacagc aaaagcatcc tcgacgggag cggcagaaat tggtttttcg      2880
     atgaaaagag aggcatcagg gaatcgcttg aggatggcca attccaaatc ggctcccttt      2940
     tgggtagagc catgggtctc aggaggaatg ccaataatgt aggcatcggg cttctcctcg      3000
     gggtggctgt ctaagtattc gaggtattca tcggcagaat aaaattcacg agtgttggca      3060
     taagaagagg cgtactcagt ctcagccttt tgcttaagga cacgttcgtg ggaactcttg      3120
     tgaggggaca agagagcaac aacttgtaaa cgatgaccaa gaacgagttc aagcttttgg      3180
     gaattattcc aaggaccctc agcagtacca aaattaatac caccgcatcc aaagatagcg      3240
     cacttaaaag gagggccagt gggttcggga gcggattgtg gaagatggga agaaatttcg      3300
     tccttgacgt tttggtaggt tttgtaagct tcgtctttaa tgttttgcat catgatatag      3360
     aaattttaga atagagaagt tttgtttcgt tgaagaaaat ggagagttga aaaaaaaaag      3420
     attaaaatat ttgtaaatgt gaaaaatcgt aatcgtcaaa aatatacaat caaacgcagc      3480
     cttttaaatt gtagcaaaaa aaaagctttt aataaaagga cgagacaaat tgtaagtcgt      3540
     atataaatat ataaaaaaga gaaaatctag caaaaataca ataaataaat tgtagtggga      3600
     tttgccaagt ttttaaaaga gaaaagtgtt tttttttgtt acactgtaaa tagaatagaa      3660
     ttcacaagct ggagaaaagt ggtttgaaga agaggaaaag cacctctatt tataatattt      3720
     gaagaagtca ttcatttcat ttgtttcaac aattttacat attcatttgt ttacgtatgt      3780
     tggaatttgg tagccggtat agcatcatta gcggtatttg aaggcagcgt catggctgtt      3840
     ttaattacat tgtatgacaa aatttgcttt acgaggtgtt ctaaccgata atcgagtgag      3900
     cgttctgata tttcctggat ggaaaaaaat tttcgcatgt ttacaacaaa tacatcactg      3960
     gcttttgata tgatatcatg taacaagtaa acttcgataa ggtgcagctt agaggtgatt      4020
     tcgttaagtt gtagcaatag ggtaaggatt gtaagaagaa aatattaggg agaaagagag      4080
     aaggagacaa aaaatagaat tagagattga gaattttgaa aagaatcttg ttatgttagt      4140
     cgtcaaaaac aaaagagtaa aagaaatcaa agaatagtgg tagacaggaa agacgtttgg      4200
     aaattgctgc gagtagttca acgacaatat cgactttgca aatagactct attagagttg      4260
     cttggagtgt aaattcattt ttgttggtag ggtcaccctt gattatcttt tctttcgatc      4320
     gctacttaac gaatcatgat ggttcgttgc tgtagaaatt taatgtactg tctttctatg      4380
     caaatcatcg aaaaactcga caaatgcgaa gaatcgtgat ttccaaaaac taaactaaaa      4440
     aaccaaaaca atgcgacatt tcgaaaactg cgacaattca tgaaattggt atcaaaaaat      4500
     caaaaatcga catttttatg aggtatagat tgttattact atttctattt attttttctc      4560
     cttctttatt tattaattct atttattttt ttttctcctt ctttttttat tattatttat      4620
     atttcttttt tctctattct ctgctaaact tagcgtatcc ttgccaatgg cttataatga      4680
     tttacgcagc cttaaatgga tcagtaacct tccttattct ttgcttcctc tcgactcggt      4740
     tcctatactg ttcctttact taaccttcgt tccttttttc catatcactt catcgcacct      4800
     ctcaatgcat gatatcagga tgacgccatt tgatgataga acacagggcc aaaggggata      4860
     ggagcaaaaa tattcatttc atcatttagc tctcatcttc ggcttttact cgtacctaaa      4920
     agccaatgaa tgaaagaaag gaaaggctag ctttcaacct aaaagtcaaa taattatttc      4980
     ttgctccaat gggttctccc tctttaacaa aaacgattaa cgcatctcta tcgcttcatt      5040
     ccataacaca gcccattacg ttactaaaaa caatgcatta cgtgttgcag cttacaatac      5100
     ttccttccgc tatgcaacat tacgcaacat tacgcaactt tacacatccg gcctgctctg      5160
     taaacaaaca agccgaacag ggtaaagaac aacaacaata tgcaatgaaa tcccagtttc      5220
     agtttcgcag tggtatttgt agcaaagttc gttccgatga gcttggtttc aaaggaaatt      5280
     cactacaatt gaatgatcta cccaagaatc cttactaatt cgtagtcgac aaaaaaacta      5340
     aacgagattt tatgatttta gtagactttt cttttctcct ttctctttgc ttttgttttc      5400
     ccttttgtct aaaaattttt tatagttctt tttcaacttc aatggctgtc tactagtcta      5460
     caacattctc ttagtgtgcg accataaacc attgtgtttg cttcgtagaa agatgggtgt      5520
     aaaatcataa atgatattat atatgtaaat atactatttt cttgcagacg tgcgaaataa      5580
     ccttacttgg aaagttccct agagcttaac gttgttcatc catatcgtga ttttgcaatt      5640
     gccaactttg aaactttaga aggacaacga aatcctttcg cattccttat tttttttctt      5700
     tggcaatggc ttgacgttcc ttatttcctt ttggttttac ttagcttagc ctagcctagc      5760
     ctagcctagc ttgaccagcc tttccatcgt acagactaaa acatctttgt cccccacttc      5820
     gtccttggat tctttcgccc accgcactag aacagaaaag cggcatccca cataaaccaa      5880
     gaccaaatta tcccacttca ttggggccat taatgaattt gtcaagacaa accgttgaga      5940
     cctcttaatg acccccattc gttctttttt cttttttttt ttgcttccga ctgttctttc      6000
     ccatcccatc cctatcattc atcaccccat cgccatccgg gcccccactc ggacccactt      6060
     tccttccttc ctttgtttca aaggcgaatt gcgtaccaca gtacatttcg ttattttcaa      6120
     aactgttcac ttttggcact gacgtttggc gatagctaat ttgggatttt cctagcaaaa      6180
     tatcccattc attcgctttt ttttagccgt gtttggaaga aaagggcgca aaaagatatg      6240
     ccaatttctg ctttttgaga tctaaatttt ttatatttcc acggtttgtt cctcttgtga      6300
     tctggcttgc ttcccttctc tctcttcctt gccttgcctt actagaaggt tcccgctaat      6360
     tccatcatcg aatcgctcac cttcatcttt tgcacatacc cctcttcctt gtcattcccc      6420
     acgtttctgc gtttaccgca tcgttcgccg aattttctat ttctttcagc gaatactctc      6480
     gtcgttacac agtgcatgaa tgtaaatgat ctcatgcaca attgctcttt caaacttgcc      6540
     ctttaccaac cactccattc ccaagttttt ggatattcag cactggttat agacgcactt      6600
     gtttaagtaa tcggtttaca tggggagaat tttaatagca catttgtttc ttccttcctc      6660
     agttggattc tccttcgata cagtcccgca cgatgaagtt ggatccaagt ttatgcaaaa      6720
     ggaagagtcg aaggattgga ttgccgatac ccctttagat gagagtgcca tcgtatcgga      6780
     agaggaatca gacgatgact ctttgctctc agacctcccc gaggagattg actcgacgaa      6840
     tgcacaaagt aatattgcga ccccttctcc cggtacagta gctgcggcga tcagcgggat      6900
     tcaacctcct cctaaaacgc cttcgtcgga ctccccgtcg ttggagaatt cgttgtcaaa      6960
     cctcaatgac ttgttcaagt cgagaggccg ccatatggct ttttccaaaa atgacggcac      7020
     caatctctct ctccctcctt ctcgtcacca gtctcctcct ccctctagtg tccttgcgtc      7080
     gcaacgccat caccgtcgcc atgacagtga attagaagag tttgctcgtc gtgcctctcg      7140
     ctctttatcc tttagtatga atggaacacc ccagcgacgt atgacttttg acgcagaagc      7200
     ttggaaaaac gttatcttta aaatcaaacc cagctccttt ggtaacgcaa gtttttacaa      7260
     tgccatcagt gctgccaccc gttccaagca attcgacgac catctttttg tcggtacctg      7320
     cggcatcccc accgactctc ttcccgattc cctgaaagaa cgtatttctc acgactacat      7380
     aactgaacac agcagtcttg ttgtctatcc cactgatacc gattttgtgg gtcactacaa      7440
     tcattactgc aagaatatcc tttggcccac cttccactac caaatccccg acaatccaaa      7500
     gtctaaggca tacgaggatc attcctgggc taattatgtt aaagtcaaca aagcatttgc      7560
     tgataccatt gttgataact acgaacagga cgatatgatt tggattaatg actatcattt      7620
     actgttagtt cctgaaatgg tccgtgaacg tcttcctcgc gcaaagatcg gctttttctt      7680
     gcacattccc tttccttcct cagaagtctt ccgttgtctg gcgacgcgtc aagaaatttt      7740
     gaagggcatg ctcggtgcaa acattttggg cttccagatt cccgaatttg cttatcattt      7800
     tcttcagacc tgttctcgac tagtcaacat tgacattcgc aagaatggcg tcgtctcttt      7860
     tgaaaaccgc cagatagatg tgattgccct tccgatctcc atcgacccag gattcatcga      7920
     tcgctgcctt gccagtccac cagtggagca ttgggccaag gtattgcagg atcgattcag      7980
     aggtaaacat attatccttt ctcacgacaa gcttgacccc attcgtggtt tgcgctccaa      8040
     gttaatttct tttgagcgat ttttacaaaa gtaccccgag tatcgtgaaa acaccatttt      8100
     acttcaggtt gcccccgaat ccctacagga cagtgagcat cttcctcaca tctccgacat      8160
     tgtcacccga ataaactctg cctattccaa cattgcctct cgtcacgtgc ccgttatttt      8220
     gctgagacag aaacttggtt atgcacagtt tttggcttta atgatgatat ccgatgcctt      8280
     aattgacaat tccttacgtg agggaattag cttgactagc catcaattta tttatgtgca      8340
     gcgcaagaga cacaggccat taattcttag tgaattcgtt ggcagcgcct ctatcttgaa      8400
     tgacaatgcc attattgtca acccatggga ttacagcaaa acagcagagg ctttccgcac      8460
     tgcattaacc atgtctgaag aagagtgcca aaaacgcaac aaggcaatgt gtaatttgat      8520
     tctccgtcac gatgctgctt cttgggcagt tactttccag agtttgatta aggaatcttg      8580
     gaaggaacaa atcgatatgc aacggattcc agcattcacc gcacaactta tcaaggagcc      8640
     ctatcaaaat gcacaaaagc gcttgatttt actttatttt gaaggaacca tttccacttg      8700
     gggttctcaa taccataacg ttatgacgag tttgcaacgt actatcaatt tgctgaacat      8760
     gttgacgtct gatcctaaaa acactgttta cgttttcagt gcgcttagct gtcaggagct      8820
     ggagcaacta tttcaacgtg ttccaaagtt gggtatcgtt gccgaaaatg gttgctttgt      8880
     tagatcgcct cctaaaggtg atgcaacaat gccagtttcc aagaaggaaa ttgccgagtt      8940
     gtggaaaaat aaggtattag gcaccgattt aacttggatg aagacggttt ctgaaatttt      9000
     cgagtactat gccgagcgta ctaccggtgc atatgtggag aataaagatg ccacagttat      9060
     tttgcacctt cgtgaagctg aagatgatga ggcagccatg tgggcagcca aagaatgctg      9120
     tgaatctgtt aacaacttca atgttccctg tagcgctact attcaaaatg atatggtcgt      9180
     ttgccgatcc aacaaagtat ccaaacgcct tgctgctgag gatatatact cggctaatgg      9240
     tggagattat gactttattt ttgcagctag taacgaccct gatgatgata cagtcttttc      9300
     atggatgaaa aatttcaagc aaagtaagaa agaagttgta ccatttacat tctctgtttg      9360
     tgtctctgaa catggtaatt ctaccaatgc cgatgctgaa agttctggtg tatttgggtt      9420
     cttgcaagcg cttgagaaag tttactccgc ttaaattata atggtctgca atttatgagc      9480
     agtttacgtg ttattttttt ttggttttat gtattgattt tacaaaacac cgtgatttgt      9540
     gaaatcctga tgacgatagt tgttgatgct tcttatgtaa gataaaattt ggaaatgtta      9600
     catctattct cagcttttgt ttgatagaaa acgttagttg aagcataaag gtagataaat      9660
     gaataaataa ataagtcatg tttacaaagg attggtcgat aagtatttga gatgccatat      9720
     caacgtagta gttaactaat attatgatct atttattgat atagaaaggt tccgccgtgt      9780
     gaatagttac cgctgcatgt tatttcattg aatcacgtac atgggtaatt tatataacgc      9840
     gaaatattgt ttttagtagc tgcagacaag taaatagttt ccttagtcaa agtttaaaag      9900
     taaagcagga aaggtgatca ccagatgcat ttaagttagt gaaaaagata ctataaaggt      9960
     agaaattgtt aatacatgaa gcaaaaaaaa ttaagggttt gaataatcca tttaagcgag     10020
     attgttttca ccttaataaa accattaagg gataaaaata aataaagtta caaaaaggct     10080
     ttttaaatct tcattaaaat actaaagcga aataactagg tatcatcctg ctatatctct     10140
     ttttgtttag gtatatttgc aaagtatcaa taagaaaaaa aaaaaaaaga ttggaaagca     10200
     aatgattaga cggtaaattc aatacgatca cagacgtatc cttgatggtt ggccttgttt     10260
     aattgaatga gttcaagaaa acaggccttt ccccaactgg cttgaccgat tgaagaaatc     10320
     gtctcaatgg ggtcggaagt agagtagtca gagcaaatac tctttgcata aatgacaggc     10380
     atatagggat gttcgatgac attaaaagga tcagaagtat cggccaagtc ataagcagca     10440
     ttttgcaatt cttccaagcc gggagttttc tctacctgaa tatatacacg tttgtagaag     10500
     gaatccccaa tagcgacttt gccgaacttt atgttcaaag gagacttgcg cttggaagcg     10560
     atatattgca aaacactctt aaacgattga tttggtttca gcttgatacc acgagctaaa     10620
     gtaatgtgag gagcggtagg taactgcatt tcttcaaagt cgactttgtg acacacagcc     10680
     cagtcgacaa acgttcgata tctcaactca atatcagagg aaatggcagg tacgagccaa     10740
     acacaataac aatggtcttc ggaagaaact tcagcaaaac catgacttgt agtcctatcg     10800
     gtcaaaggct gggtcctgaa aaattggggc atgatgaagg agaaagctag atttcctaat     10860
     tacaaggggc tggaaaaaat aaagagtaaa aaaaatttaa aaggttgtca gcagtgaaaa     10920
     ttgtatgcaa cgctataatg gtgttgaaaa gaggaaaaat aaatataaaa tacgtataaa     10980
     tccttcgcca atttatttca acaaatatgt agtcaatatt ttgcgtattt tttttaatac     11040
     cacactattc ttctttatta gtaaatgaaa ctccaaaaaa aattttcaca tacagttaaa     11100
     tttctgtttc aagagtaaaa ccgatatttc cttgttcgct tcgaaacctg tcaatgcgct     11160
     tttttcgatt gcaaggacag aacactaaaa aatataaaat acactcaagc aaagaatgta     11220
     tttaacactt gatttatttt ccaaattgct tgtataagaa atagaacttg attaatattg     11280
     ttgaacagtg agttggttcg ttggtctgct tataacagct ggtgctttca ccacactatg     11340
     atgtcatcgt agcgatgcga taaatagaaa cagcacacag gtcactttct cgtccgaggt     11400
     ttagcgctca tttggccgtg tgcggaagca tgtgcgggtc tctaaattca cgctttataa     11460
     atggtaagat ggcgcaaaaa actgtgtatt ccatttaaca gcatatttgg gtaaacctat     11520
     aagtgcctga tatacatatt gcgcatttta tgaataaatt ttatacagtg aagtgcaatg     11580
     cattgcagaa tcatttgtta gatatgcggt atgcttgatc tgatatgacg agtggatttg     11640
     ctgtgttttg tagtcaataa acaaacaact aaaccttttc aaaaaataaa ataaaattgc     11700
     aagactaaaa agaagcacta taatgaggcc cctttatttt tatgtttcgg aattacctcc     11760
     ttttacttcc tcttaaaacc gcaaataagt atatgcgttt ttctactcat aaagattttt     11820
     accttttata tcttttaatc gtgtagaaat ttgttattta tttttattaa ccttttgtac     11880
     ttcatttcat atcattttat ttatttcttt atttgttttt ttaattgaga tgtaataatt     11940
     ataaatttcg ggaattggtc aaactatttt ttttcataca ttatctggaa aatagaaaaa     12000
     aaagcgtatt gaaatcgatt catttatgtt gagtatcttg aatttattgg ttcaagattt     12060
     taacaatcaa ctaacagatc gcatatttca ttaaataacc gtgtaggttt tttatccttc     12120
     gcccttaaat acgctcgttt atttaatatc attattaaaa ttctattttt gtataatttc     12180
     taatggtcct ccttcataga agaaactcaa gaatatatgt ttgcaaatat acttctataa     12240
     ataaataata gacaaagtaa acgatgtcct ctttaccttt aattttatgt tctttgctcc     12300
     tttgcacttg gtttgttcca agatgaacga gaggatcgtt ttcttccttg cccggttcgg     12360
     gatgcctttg agacatttct ttttccaatt actttggtgg gactgtcagc atcatagtca     12420
     atcaaaaatt catcaaaatc aattcgatca cgcaagatgg ataaagctac tagttcaatc     12480
     ttgtacacat ttaaaccagt agcactcata ttccgtcctt cttgatcgtt gtcaggttga     12540
     gcaagtataa ttgtgtcctt ctcttgagcc cttttaatat caccaacaat ctatttaaat     12600
     cattagccta tcataactag atattctcca tctttcactt acctcagctc cagatgtttc     12660
     caaaattgag taaagtccgt gtatagaatc ccctaccatc gaatctcgaa ttgcctttgt     12720
     aatgtatagt cttttcccat tgaaacacgt tcttctgtgg atatcgtcca aacgaaatcc     12780
     ccacttggct tctgcttcct cgtctttata tttgtagcta cgaaaatcta aaactttacc     12840
     tgattttata cagtctgtca agtattgaga agagacaagt ggtataccta gagaagtcgc     12900
     cagtaaaaac ttatgtgtcc tccgaagtgg aggtgaacca aggatgacaa agtcggtttc     12960
     gtctgtgaca ctttcttgca cccttagacc atttctcctt ataaaacttt tcatcggttt     13020
     agttaggttg aaactcgacg ttaccagatt tgtgtgcttg tttttatttt caactgccga     13080
     ggactgcaca ttcttgtcag gttgatcctc taaagatgat gaggggaaag aataattagt     13140
     ggaaattggt gcctcttctg cttctctgtt actttcatcc tgggatgtgg attccttctc     13200
     tttgagagcg atttccggcg cacttctttt actttcttca ttttcgttgg agggggttaa     13260
     atctggccta acctctggat ttacttcatc actgtgaatg ctattgttct ttatagagct     13320
     gtccgatatg ttttgctgtg gattcacatc cttctcaatt ggtgagttta tttcagcact     13380
     ttgctttcta tcaaatacct ctgctggctt caaggatggg tctccactca atgattgcga     13440
     gacagaagaa ggagattttg tttctccttg tatataaatt tggtgtgatt caataaatgt     13500
     tgactcatcg tcggtcttat tcaactgttt ttgatcttca gaaacaacct cctcttcagt     13560
     gtcagaacta tggtcgcctt ccacatgttg accgtccaat accaattttt cgtccaaatc     13620
     attctcagag ttttcaactt taagaacagg ctcagcggca gattgcgatt ctggaattct     13680
     ctcagaaaag agttcctttt ccaattctaa agcacttttt tctgaagcga atcgcgaaag     13740
     gggaatgacc tggtcagatc cttgcctaat taaagaattg taattttgtt ccaagttact     13800
     tgaataatca atttgatctt cattcgcatt gatcgcttca aatttttgtt gctgcaaatt     13860
     tggcttctgc ggggtattag ggaccttgga aaataggtta gtgtcttttt gacaatagta     13920
     taatgaggga atgcacatac agtcataact cccattttgg atccttcatt cacgtttgca     13980
     ttatcctcct ctaattttga aaaaattaca ggagtatcgt tgattcttac tctctaaaaa     14040
     agtatataat tagcttactc aattaatcaa tagaaaaaag ataataccgt ttcgtcaaaa     14100
     acataataaa gaagcttttt gtcgctagca gatggaagca ccgttgtatc ggctatttta     14160
     actatagctc gaatatttcg aataaaaagt tgatgttcta tatttaagaa ttcaacaaga     14220
     acatcatctg tttccatttc cttcagatgg gaaccatcag tagctagaaa acccccagaa     14280
     tttaccatcc tacacctctg atttccaaac tgtatctcca ttttacaaat cctgctattg     14340
     atcgtataaa aatttcaagg aggaattaac aattaatgtt ttggttactg cgtgaaaaag     14400
     cttagcaaca actctgtgat taattcatcg aatggttaag aaatgcgtgg tatagttaca     14460
     aggatagtgt tgtcaacgca aaagtgtcta ccttctgtaa attgtactag gagatactat     14520
     tcaaaacaaa aggatatttc tattgttcgg caacgattgg gacgacctgg aaatcatttg     14580
     aaaattggca ttgtaggaat gcccaacatt gggaaatcca ccttattgta cgtttgttca     14640
     agggtttaac tgataaattt gcttcattga tcggtattaa caataaatat agtcaaattc     14700
     ttacaaagac aaacctggga aatcctgcta actgtacgtt gtcatatttt agtcaagtat     14760
     tagttttgat tataagtgat ataatatttt gtatttctgt tgtctaacaa aacaaattta     14820
     taagaccctt tcgctacaat cgatcccgtt catgcaaaag cccctgtact tgattcacag     14880
     tatgaattgc tttgtgaaat ttatcagcct aaaacgcgta tcccagcgca attaactatt     14940
     tatgatactg cagggttgac aaggaattca agcaagggag aaggtcttgg aaatgcgttt     15000
     ctttcaaaca ttagatccgt cgatgctttg tttcaattgg tacgtgcatt tccagaggct     15060
     caagttcctc atgttgaaaa gtcagttgat ccagtaagag atctacaaat aatacaggaa     15120
     gagctattgt taaaagacgc agagttttta gaatcatatt taaaaaagga gggccgctcg     15180
     cccaaaacat gtgcaaaagc tcttgatacg gcacgaagag cattagaagt agtattagga     15240
     aaaggccgtc aaatatctaa agctgaatgg aatgacgagc agattcccat tttaaattct     15300
     ttaaacttac tcactgccaa accggtggtg tatctggtaa atatggatca agacgattat     15360
     ctttccgatg aacaagaagc attaaaagga atcaaagaat gggttgagaa aaatagtttt     15420
     ggtgatcaag tgatacctct ctcagttctg tttgaagaac agctattcat gcttacgcct     15480
     gaagaggcgg cgcaggaatg cgctagtttg ggcaaaaatt ctcaattatc agaaattatt     15540
     tgtgcgggat attctgcact taatttgata cattatttca cagctagtga aaaaatcgtt     15600
     caagcttgga ctattgccga cggctctaag gcgcctgacg cggccggtat aatacattca     15660
     gatttcaaga agaagttcgt tgcaggagaa gttataaagt tttctgattt cgaaaagtac     15720
     aaatcagtag atgcttgtaa aagcgtagga aagtgcaaaa cgaaagggaa agattatact     15780
     gtcgaacccg gggatattat tttctggaaa attgctcgtt agtgataatc taaattaaat     15840
     taaattaatt atagtaagat ttcattaata ccgttttcat aatgtttctt ttcaagtgtt     15900
     tattagttat ttgtttacaa aactttatac ttgtaggata gctttaatta cattaaatta     15960
     tttagtgcat cggtgtattt tgttaaattg gcctctaaac agtaatgcct acgtactgtg     16020
     tgtatgtaaa cacataattc aacctattgc catatttctt acatattacc ctttttttgg     16080
     gtgtaatagc agtagtcaga attctgggtt gttttatctt ttcctttcat aaataaaaaa     16140
     tggatgggaa accgcaagtt gaagtgatag ttaatggaca agttgttcca aatttggatg     16200
     atagagagta tcgtcttatt aagttggaaa acgacctcga ggttttgcta gtgagagatc     16260
     cggaaacaga taatgcaagt gcagctattg acgttcacat cggcagtcaa agcaatccac     16320
     gagagttgtt aggattggcg cacttttgtg agcatctgtt gtttatgggg actaagaagt     16380
     atcctgatga aaatgaatac agaaaatatc tcgaatctca taatggaatt tcaaacgcct     16440
     atacagcctc taataataca aattattact tcgaagtgtc tcatgatgct ctatatggtg     16500
     ctttagatcg ttttgctcaa ttttttattg accctctctt cttagaagaa tgtaaagatc     16560
     gtgaaattcg ggctgtcgat tctgaacatt gtaaaaactt gcaatcagac agttggagat     16620
     tttggcggtt gtacagtgtt ttgtctaatc caaaaagcgt gttttcgaag tttaacacgg     16680
     gaaacataga gacgcttggt gatgttccaa aagagttagg tttagatgtt cgccaagaat     16740
     tacttaaatt ttatgataaa tattattctg ccaatattat gaagcttgta attattggac     16800
     gcgaacctct tgatgttttg caagattggg cagctgaatt gttttccccc ataaaaaaca     16860
     aagctgtccc cattcccaaa tttccagatc ctccctatac agataatgag gtacgcaaga     16920
     tttgttatgt aaagccagta aaaaatttac gacgtttgga tatcgttttt ccaattcctg     16980
     gtcaatatca taagtataaa tgccgtccag ctgaatatgt atgtcattta ctaggccatg     17040
     aaggagaagg ctcttattta gcttatttaa agagcttagg gcttgcaacc tcccttatag     17100
     cctttaatgt ctcaatcacc gaagatgcag acatcattgt tgtttcaacc tttttgactg     17160
     aggagggttt gactgattac cagagggtta ttaaaatttt atttgaatat ataagattgc     17220
     tcgaccagac aaatgctcac aagtttttat ttgaagaaac ccgtatcatg tcagaggctc     17280
     aatttaaaac gagacaaaaa acccctgctt accagtatgc gcatgttgtt gctagcaagc     17340
     ttcaacgaga atatcctcgt gataaagtcc tttattattc ctcagtactc actgaatttg     17400
     accctaaagg tattcaggag gttgttgaga gtcttcgtcc taataacttt tttgccattt     17460
     tagctgctca ttcaattgag aaaggacttg ataataaaga gaagttctat ggcatagatt     17520
     acggattgga ggatttggat tctcagttta tagactcttt gctacatatt aagacatcca     17580
     gtgaacttta cttgcctttg gcaaatgaat tcattccttg gtctttagaa gttgaaaagc     17640
     agccagtaac gacgaaactg aaagtgccga atttggtgcg aaatgacaaa tttgtaagat     17700
     tatggcataa aaaggatgac actttttggg tacctaaagc taacgttttc ataaatttca     17760
     tatctccaat cgccaggagg tctcccaaag tttctgtgtc gacgacactt tacacgcgat     17820
     taatagaaga tgctctagga gaatattctt atcctgctag cttagctggt ctttcctttt     17880
     cactttcacc atctactcgt ggcataatac tttgtatttc agggtttact gataaattac     17940
     atgtactttt ggaaaaagta gtcgcaatga tgcgtgatct caaagttcat ccgcaaagat     18000
     ttgaaatatt aaagaatcgc ttggaacaag aacttaaaga ttatgatgct ttggaagcat     18060
     atcatcgttc aaaccatgta ctcacatggt tgagcgaacc gcattcgtgg tcaaatgctg     18120
     agttacgtga agctattaaa gatgtccagg tgggcgatat gtctgatttt attagtgatt     18180
     tattaaaaca aaacttttta gaatctttgg tacatggaaa ctataccgag gaagatgcca     18240
     aaaatcttat tgaatccgct caaaaactga ttgacccaaa accagtcttt gcatcccagt     18300
     tgagccgtaa aagggctata atagttcctg aaggtggtaa ttatatttac aaaactgtgg     18360
     tgccaaacaa ggaagagaaa aattctgcta ttatgtataa tcttcaaatc agccagcttg     18420
     acgatgaaag atctggagcc ctaactcgac tagcacggca aataatgaag gaacccactt     18480
     tctccatctt gcgtactaaa gaacaacttg gttatattgt ttttacttta gttcgtcaag     18540
     tcacgccttt tataaatttg aatatttttg tgcaaagtga gagaagtagt acatacttag     18600
     agtccagaat tcgtgccttg ttggatcaat tcaaaagcga atttttagaa atgtccgacg     18660
     aggatttcag taagcacaaa tcaagcttga ttaactttat gctcgaaaag catacaaact     18720
     taaaagagga atcttctatg tattggttac gtatttgtga tggattttat gactttacca     18780
     gattggaaaa gcaagcagaa attgtgtcta ccattaccaa ggatgagttt tacagtttct     18840
     tcataaacaa cattcattat gaaggagaaa atactaaaaa aatatctgtg catgttgttt     18900
     ctcaacgctg tgaagatgaa gtttacgaaa ttcccaatgt tactatcatt gaaaatggca     18960
     acatgttcaa ggaaagcatg acattgagta aagcggcttt cccacttaaa ccctttgatg     19020
     aaatcgatag gtctttatta tttaattagt tttttttccc taatccgatt ctcaaattta     19080
     ctgattttat attctcatct taatttcagt tttgcattct ggcactgcgg tttttctcgc     19140
     tatccaaaca agtgtgacga gacctactct tctgctagct gcaaagtctc tttttcatag     19200
     attttgtaag caatagtaaa acaattgttt ttttttatga taagatattt attttaaaat     19260
     gtcgtctaaa cttctttcta tgaaagtacg aaatttagtc aaatttttaa gaaaaatttc     19320
     tactaacctg tattttgtag tttatgcaac gcgctcgagg cattgacccg aagcaagcag     19380
     aagaagagtt aagcaagaac attgttacag atgagcattg gagtcttgca ggaaaagttg     19440
     attttttacc ccaaaagatg actcgtaatg tagaatatga atcgggttat gggggtctga     19500
     ttgaagaaaa cgatcttgaa agtcattcaa atgaacctaa tttagtacaa ggaagagcta     19560
     gctttggatt atttaataag gaactaggag aggaaaatgt ggatgaaaaa gatgtttcta     19620
     agaatgaaga ggttgatgta aacggtacta aaataacgga cacatcggag cttacagaaa     19680
     gagaacgtcg taaacaagaa ttagtgtcta aaaaggcgga ggcatcccgt aaaatggagg     19740
     tgaaggcccc ggcaaaggaa tccaaaaaga ggaaagttaa tgagttgtct caagatgtca     19800
     tttctctaca ttcccccaaa gagtccaatg cccgaaaaac aaagaaaaat aaaaacaaaa     19860
     agaagaaaaa acgcaactaa gagttgctca tttttttttt caatttgact ggacgttcat     19920
     tgtatgaata agggatgtga agcatttttg ggtactgtaa atattaatta aaattttctg     19980
     aattattatc atggtccttt ctaactgtgt attattaaac ctggagaaaa aaagagaacc     20040
     gctacatatc aacgatgctt ttttgctatt aagatgtaaa tgtaagagtt tgaaactaca     20100
     gcagtagttc atcgttgtcg ttttacgaaa tctgctaggg agaaagaatg agaaagaaca     20160
     gtagaaatat gtatttacta tataatgaaa atagtcatga atagaccata atttgagacg     20220
     aatgaatcaa tatttgaacg accgtataac ataagcatat aaaaacattt aagtcgattt     20280
     acgtaaagcc gaggtaagta gacagaaaaa cataatctac tctatatcac cacgttgttc     20340
     aggaaccaaa ttgggaagtc tagaaaaaaa gttagaaatt gaaagaaagg ggaaaaacat     20400
     aaggacttac gaatcattga caattccatt tttgacgttc atgagaacag cgcattccat     20460
     tttgtattgg gtctcaagac tgtttgtacc taaatgagga agaagaatca ccttttcgtt     20520
     ctccaaaaga ccaggatgaa ttttgggctc ttcttcaaat acgtcaagac cggcagagta     20580
     aacgatgcct tcgtcgagag cttcgacgag agcagcttca tccataacgg caccacgtgc     20640
     agtgttgacg atgacaattc cacgcttcat cttttgaaat tctggttttc caatgatatg     20700
     ccgggtgtga gcattcaagg gcaaattgag ggaaagcaca tctgacttgg ctaaaagatc     20760
     gtcaaatgag acaaactcgg caccttcagc ttcttcctcg ggaaggggag tacgattgtg     20820
     atatacgatt ttcatgtcaa aggcgcgagc acgcttggcc atggtcttac caataccgcc     20880
     caaacccaaa ataccaagcg ttttaccctc gggatcatga gagggtttgc aatttgcatt     20940
     ccagttgttc ttgtgtaact caaagatacc ttggttaaat ccacgaaggg cacctaacat     21000
     taagaagata ccaacgtcgg cggttgcatc gtcgacagcc ttgggaacgt gggagacttg     21060
     aataccacga gcggtacaag cagccacatc aacagtttca taaccagcac ccaaatggca     21120
     gataaacttg acggatgggg gcaaattatc aatgatttcc ttgtcaaaaa tgcccatgta     21180
     aaacttggag ttgtaagtac gacagatggc ctttacattt tgaaactcgg ttttgcattt     21240
     ggccaagaag tcttcgcgag tgccatcgct gtaggtctaa aacgacatta gtaaacaaga     21300
     acaggtaaac acaactaagc gcatatgttg aggttttgtc gggaagctag gagatccgct     21360
     agatagccaa gaaatccaac agaatcgcag aagcagagga cgagggagaa gaagcaacag     21420
     aacaacaaac aagcaatcac tcttgaattt tttagttcca tatcctctgc tcatccttca     21480
     acctccatct cccactactg tcccttcttc cctcccttct ctatttcttt accttcaact     21540
     ctgcatattt tccaagagct tcccactcct tatgagcgtg cttcaaagtg ccaacgagta     21600
     aagctgcagg ttttccacta agagtcatga tgaatacaag tcgttgagag gatgagacga     21660
     tcgattgatt attttacaga accttcgtgc ttgagttctg gtatagttga tatcttgaat     21720
     aaaggctttc tgtcaaacaa aagcaaatcg cacacacaaa cacacaaaaa aaccgctgta     21780
     caactattta gaaatctcga gttgagtaca acaaagaatg tgatggagat gtggggaaag     21840
     caggatattc ttcgcttttt atgcttttct gaatgaacaa aaaggcaacg attgtaacag     21900
     cgatagttga acttaggttt agtaagattg gttaaacagc ggagaactga ggtgtttaat     21960
     gtctagatcc cgcactctgc gttcttttct tacgtacaca cgcactctaa ataagactat     22020
     accaacctga accaacttgg tcaaatctta aggattagtg tgcctgctgt tccactgcac     22080
     ttaaatagtc ttaccggctt atctatgatg ttcgttatct atggatcacg tgggagacga     22140
     aggaggagca cggtacatga tgctgatata tggagattag gaggatgggc gtggtacatg     22200
     gaattgtaag cgagcgtgca aagtagaaag aaaagtccac taacaagagg agaggaagta     22260
     gaaagggaga atgtgtgagt ggggggatgc gagtgatcgc tgagtgcaag catctgtaga     22320
     gttagtggta agaaaacatg gttaggaagg atggaattga aactggttta aaaactcgaa     22380
     ttgtagtggt acaaaatgaa acacataaaa gtagcgatgc aaaaacattg gatcaaaata     22440
     tccgcatatt ccgaggacaa atacgttgcg aacacaacta ctttttactc atcttccatt     22500
     tgtttgtcgc catagattga atcgatagtg taggggagct cccaacttat agatgatcaa     22560
     cacttttttc gcaaccaaaa tagtcacttt ggtagtacaa gtttaggaca ttttttccag     22620
     gtgtgcatgc agagacaaat gggactcgta aattggtact aattcgtttg tttgtttgaa     22680
     aatcaccgac acacattcgt ctacacaaat catcgcaatc tcattgtata caaagtgccg     22740
     gttcacactt ccacaattta taacccagat gcttcattag cttagaagca gataaatctg     22800
     cttgacttgt ttcttagtca tagtattcat ttcatctaca aaagtgttag agacacaatc     22860
     tagttattcc cacttgcttc ttagtaatgt ttatgttgta aacaatattt cctcaataca     22920
     accaagtcat ttcctagtca tattatgtct catcaacaaa ttattacata cgcacacttc     22980
     aaaccagatc aataaaactc ccttgttaca atcaaacttt taataaagca aataattttt     23040
     tcaataaacc ttctaaatgt tttttcctct ccctactcta ccttttgagc aagcaaaatt     23100
     tgcactggac ggccgtcttc gataaatcca atctcatctt ttaaaaccct aattcgtcca     23160
     tccgactctg aaactattgc tgccgcttct cctttttcga atctatgatc acttcctcta     23220
     ggatgttcat actgatgcac cccatcgttg acaaatgtac acaagaagag aaatccgtta     23280
     tttctcaata atgaagaact ttgtctcagc aacgcacggt ttaagaatcg aatttgtaga     23340
     actaaatcgt atttgtaaac atcaccttct ggaacgtttt gaaaatcagc tagcatatct     23400
     gccaaagaga ttgccgttgc gtttggctct tgttttccat ctctagtata caatttccat     23460
     aatcccgatg catctacttt agcaactttt tttccttcta tcctatcctc tagacctaaa     23520
     ccgctgaaaa gctccgaaaa tctttgaatc gcgcgctttt cagcatctaa tgcagaaacc     23580
     atccaatgtt taccgctctc tctaaaacat atccatgcca aatccctccc agatccacat     23640
     ccaatgtcta aaactcttgc attatttgtc tttattcctt tttcaacgac tggcatgacc     23700
     tcttttaaat acggacatgg ttcaaatagt aaatttcgat ttggaccgct ttccaaaagc     23760
     tcattctgag gtaaagataa atcttcccat attttatgac tgaacataaa gtgtccagct     23820
     atattccatc ctctcttctt caattgttga gcgcaggttc ctgtctcttc cgtctctatt     23880
     ttatctccct ggtcttcgac aacgaagagt tcctcttgct ttgctggtaa ttgataccag     23940
     catttagaaa ttttttcact tggaatattg actgactttc gtaaatggct gatttcgtac     24000
     ttggattgag cacgaacatc taaacattta atctcacctc gaaccacggc ctttacgaga     24060
     tgttttggat catttaaact attcatttgc atattcaagg gtcacataat cttcaatcga     24120
     attgacttga acaatttacg cacaagttaa tgccgtttta gaactttgga agttggttac     24180
     tcgaaagagc acataaagtt agcttaagaa aattacatta taattgaaat atctaaatta     24240
     aaatgaccaa ggtcacttga caagtgaaaa gtttaaaatt aaaggcagta cataaacatt     24300
     aaatatttgt catcgtttct caatcccatc gatgttgtcg aacaccggta gacggatcta     24360
     ttcttcctaa cgcatctcca atccactcac ttagacgatg ataaatagac aaactagcgt     24420
     tatggtagct aatagagtgt gcgctatcgg gaaaaaccgc catgtcatag ttataacagt     24480
     ttgcgaggtt aagtccatcc atcaaatgca ttgagtgttg aaaatgaaca ttatcatcac     24540
     ccgttccatg tgcaacaaag aacctcttta actgtttaaa cttttcgtag tcatgaattt     24600
     gcgaattttt gtagccttct ttattatatt gcggaaggtc catgtatctt tcggtatata     24660
     cagaatcata aagacgccaa tcagttaccg gggctacagc cattccatac gaaaaaacgt     24720
     cttgtgtttc caatgtcttc aatgtcagat accctccata actccaaccc catataccta     24780
     catgattctc atcaacaaat ggcaaatccg cccaaaattt accagcttgg ccttgatcgt     24840
     atgattccca ttctcctaaa tgccttgaca cagaatatct aaaagcatta ccattaaatc     24900
     cagtccctct tccatccaat gttaccacaa tgaattcaaa gtctggatga gaagcgagat     24960
     aagcttgaaa gtcaactctg aacaatttag caacttgctg agatccaggg cctccataag     25020
     caaaaaataa aactgggtac tttttgttaa catcaaaatt tctgggtcgt cgttccataa     25080
     aattaaacgt tgtatcatta aaagttaatt tcccgtattc aacactcggt aacgtaattg     25140
     aagacaactg ctgtttcaaa cgtgagtttg tttctaaaga cagacaataa tctttgtctt     25200
     tagttgatcg aagctcttgc catggaacgt caggtccatg ataatttaga acataaaaat     25260
     ctccaaaagg ggaaaacgag gtagagtagt aaccctcatc ttctccatta tctgtaattc     25320
     cgtaaatttc taatgtatcg agagatacat aataaagatg cctttcggta gaatctttta     25380
     aagtggccaa aaaatataca tttccaaaat ctccatctat gtgtattggg ccgtctgtta     25440
     catcccaggc gccagatgtt aaataaatag gagaagaacc attaaatgga ataaatgcca     25500
     aatggttata atcatctaaa gctaaaatat caaaatatcc atccgaccaa ttttcccaaa     25560
     caagagaatt atttaaagga aacattttag cagactgttg aacctcatac caaccttctt     25620
     ccaaacattc cgttttcact gtatgtatac ttttcaactc cgtatccaac aacctcgctg     25680
     taatgcaagt gctattacga ttggtaaatt gaaccaatac actagaggta ttgacccaga     25740
     gtacattttg aacgactggt tctgccaaag gttcgttatg ccacagtgaa aaattagagg     25800
     aagcgttaga attaaggtca gcgacaaaca aagaaacaga aggattcgga ttacctggct     25860
     ttggatattt aattgccatg tccttgttat aatcaaattc cggcaaactg ggatctagct     25920
     cagcggtgta taaaggatag tgataagtag ggatctctga ttcatttagc ttaagaaaag     25980
     caattttatc tgaatccgga gaccaccaaa tcgttgaagg actggaaagt acttcttctt     26040
     cataaatcca atctgtcaac ccattaaata cgtcaacggt accgtcataa gtaagtcttt     26100
     gaacatttcc atcgtttttt cgaacataca aatcattatt atagacgaag gaaagttgat     26160
     gaccagtagg tgaccattcc gcaaggctta tagtccaatg ctcgttgtcc tgacccagca     26220
     tattgacatc cttagtttcg gtattataaa gataatattg tgcaaatgat gaatgtctcc     26280
     accgttgaga cttattgacc gagactaaca cgtactttgc gtcaaaagat atagaataac     26340
     tgtcataatc gagctggatt ccattataca ctaaatctga aaccgagaac agagttttgt     26400
     taagattata aggatcttgt atattaatca aatcaccgta ttttactaaa aaagtatcct     26460
     tcaagccttg gctatcaatc caattgactt gtttgtatga aggtttgtat ttttgaagaa     26520
     caatatcatc taaactcagc gagtctcttt tcggaggaga atcgctaacg ttggaaattg     26580
     tcaagtaaag aattaacaaa ctgaatatca aagccaaagc tttaaccact cgtcgaacat     26640
     gacgactacc aaagccactt cgactaatca aacccttgtc ctcaaaacta aaatcattca     26700
     tttaggtagt aattgatctt caaaaagtag aatagtatat atatatatat atccgtaaag     26760
     aatgaccaag cgtgttaaag gatcaaggaa gatatcagaa aagtaaaggg tttgtattgt     26820
     tcacaattaa tttacagttt aacgtcttca cgaaataaaa gtggctgtct cagcattaaa     26880
     ggcgagtacc ctgatagaat actgaagttg cgtttattga gttcagtagc gtcaatccaa     26940
     gaaaaatatt gttttagttt aaaaacaaaa taaaaattaa aaaaattaaa cccttttgga     27000
     aacagtaatg tatattcctt cgaaatcgtt atgcttgttg gtgtacagaa atataagagc     27060
     gatactgaaa ttgtgctgta ccaaaacctg cccaacacac cacattagaa tactgactgt     27120
     aagtagtaat tgcttcagtt atctagaaaa aggaattata tggggagtaa ggctttaatt     27180
     actagcccag acataagttc tgggcaactt tatataaagt tgcccacatt ttttcattta     27240
     tatgtgtggc cttttgcatt atttgtgtac ccctatattg gatatgtata tcaaaacaaa     27300
     ctctattctg aagaggttcg ttatttaaca tacattgctg tcggtactat tcatgcatta     27360
     ttctggctag ctggtgaatg gaacacgaag gtttactgtc tcatgacttg tcgaaaaact     27420
     gacaaggtcg aacaagctac tcatatcctt gttactccta gtaaaatagg agaatcatct     27480
     agtgtggagc caatcactaa gttggttctt cctgactcac aaacgattca gtacagcttc     27540
     tcttttcaac gtaaacggtt tatctatgaa ccagaaaaag gatgcttcgc aaatataact     27600
     tttccaatgg atgaaccttc aactattggg actctcaaaa aaagtacagg gcttaccaat     27660
     attcaatctg aaatatttct ttatcgttat ggtaaaaatt gcttcgatat acctattcct     27720
     acctttggta ctttattcaa ggagcacgca gttgctccat tttttgtctt ccaaattttt     27780
     tgctgtgttt tgtggtgtct tgatgactac tggtactttt ctcttttctc aatgttcatg     27840
     attattgctc ttgaatgttc agtagtatgg caacgtcaac gtacattgac cgaatttcgt     27900
     actatgagca ttaaacctta tgaaattcaa gtttatcgca ataagcattg gttccctatc     27960
     tctaccgaag atttgcttcc aaatgatgtc gtatctgtcc ttcacaataa ggaagacagt     28020
     gggcttccat gtgatcttct tttactttca ggttcttgtg tagtaaatga ggctatgctt     28080
     tctggagaat ctacacctct ggttaaggaa tctattgagt tgcgccccga agaagctgtt     28140
     attgatgtcg atgagcttga caaaaacgct gttttgtttg gaggaactag ggttcttcaa     28200
     gtaactcaat cgccgttttg caaacttaag actccagata atggtgttcc tgcaattgtt     28260
     cttcgtaccg gatttgaaac aagtcagggt tctttggtac gtaccatggt attttcttcg     28320
     gaaaaggtca ctgcaaacaa tcgagaaagt ctttacttta ttctattttt gctagtgttc     28380
     gctattgcag cctctggata tgtttggcat gtcggcagta aaactgagcg tagcagatac     28440
     aaattaatgc tcgattgtgt tatgattatt acttctgttg tcccttctga actccctatg     28500
     gagctttcta tggctgtcaa tgcctcatta ggtgctcttt ctaaatatta tatttattgt     28560
     actgagccat ttcgtatacc actctccggt catttggata tctgttgctt tgataagacg     28620
     ggtaccttaa ctgaagagca tatggttgtt caaggtattg ctggagttaa tagaaaggat     28680
     ccttatagtc ttgaaaaatt aagcgatgct tctaacgatg cgatactggc aattgctacg     28740
     gcacatacct tagttttgct ggaacaagaa ggtgaaactc ccaaagtcgt tggtgacccc     28800
     atggaaaagg ctacggttga aaacttgggt tggtctattg agaaaaagaa ttttgtttca     28860
     gcacctgaag gttctgtttt ttataaaggt aaagttcaaa tcattcgaaa cttccaattt     28920
     tcttcagctt taaaaagaca gtcttctgtt tccaacgtaa gagtgtctgg aggaagtttt     28980
     aaaacttttg tttcggtaaa aggagcccct gaagtgattg ctactatgtt gcgggaggtc     29040
     cctaaggatt atgaaaaaat ttataaagat tatggtcgta aagggtctcg agtactcgcc     29100
     ctaggttata aatattttaa aaattatatc cctgagaatc aagtttctga tttgagccgt     29160
     gaatctattg agtctgacct tgtatttgcg ggattcctta tttttacttc tcctcttaaa     29220
     gaggatgcta ggcaaactgt gcaaatgcta aacaattctt cgcatcgttg catgatgata     29280
     actggtgaca atcctctgac cgccgtatat gtagctgaac aagttggtat tgttgaaaag     29340
     ccaaccctcg tattggatat taagcatgag aatgaaaaga ttttagagtg gaagagcaca     29400
     gatgatacaa tcaatttacc catgaatcct cataaatcgt tggaagcttc gttgtacgaa     29460
     aagtatgatc tttgtattac cggtcgtgct ttgtctcaaa ttatcaatcc ggacgttatt     29520
     atgtcaattt ttactcacgc ttgggtttat gcgcgtgttt ctccttctca aaaagaattc     29580
     atgatctcaa ctttgaaaca caatggatat ataactctta tgtgtggtga tggtaccaat     29640
     gatgtgggtg ctcttaaaca agcacacgtt ggtgtagctt tattaaatgc ttcggaagaa     29700
     gatatgcttg aaatgcaaga gagagctcgt aatcagaagt tgatgggcgt ttatgaaaag     29760
     caaattcaac ttgctaaaag atttaatctt ccaactcctc ctgttccacc tgcactttgc     29820
     catgctttcc ctcctggtcc taacaaccct catcgtgaaa agactcaaga aggcttaaat     29880
     aaggtcctgg aagatttgga aactaagaaa gctagtgatg ttcaattaac ggaagctgag     29940
     aaagctgctg aaagacgggc aaatctggct aacaagatgt ttgacacttt agcaaacgct     30000
     tctgatgatg aggcaccgaa acttaagcta ggagacgctt ctgttgctgc accatttact     30060
     tctaaattag ctgtagtttc ttcgataacc aacattgtgc gtcaaggtcg ttgtacttta     30120
     gttgccctcg ttcaaatgca taagattttg gctctcaact gtttgatcac tgcttactcg     30180
     ttgtcagtac ttcatctgga tggaattaaa tttggtgata ctcaatacac tatttcggga     30240
     atgttaatgt ctgtttgttt ttactgtgtt tcacgggctc gtccacttga aactctttca     30300
     aaagaaaggc ctcaagctgg aatttttaac acttacataa ttggttctgt tttaggtcag     30360
     tttgctattc atatcgttac ccttatctat ataactcgtg tcgtttatct gtatgaggat     30420
     cctttagaaa aggtggattt agaagaaacc ttcaagcctt ctttgttgaa tactgccatt     30480
     tatttgcttc aacttattca acaagtctca acgtttgcta tcaattatca gggccgtcct     30540
     ttccgtgaag ctttaagtga aaataaagga atgtactatg gccttttggg cattgccttt     30600
     gtcgctattg ctggtgtaac tgagttttcg cctgaactca acgcaaaact tcagttagtt     30660
     aaaatggctt ataatttcca gatacaactg ttagccacaa tggttgtaga ttacgcggct     30720
     tgttggatta ttgaagagct tatgaaaaaa tacttccgtg acaacaagcc gaaggaaatt     30780
     gttcttcgta attaagaaca attatataag tgggttacac ctacttatct gtacaagctt     30840
     agataaatat tcatttgaac aaactgatga gtaattgcat tactcactga tgggcaagga     30900
     tgtcaatttt cttcggtcag tatacaatat ttatcaccat tttcaatttg attacttgtt     30960
     atgaatattt tacatagact caatgattga ttcattcttg gcatatttga tttattaatt     31020
     tggaatagtg taagtgagct ttttatagga cgtaatagat gcttattaga gataaaataa     31080
     tattcacttg ttaaaatcct tctcagtagc aaggtgaaag gcatataaaa tttgggatat     31140
     ttctataagc gctatcccat gatactggga cttcgtaaat cctcgaacgc tcagcatata     31200
     tcaagcaatt gcgaaaaccg ctgaaaaatt gggataattt aatttaataa aaagagctaa     31260
     gctcatttaa agtttttttt tttaatgttc atcatttttg ccctattttg aaccaaaatt     31320
     ttacagtttt aatacgcatc gaccgatcga gttgaattgg ggcttttctg cattaactta     31380
     tcgatacaat gcctttcttc ctcaaagagc tttcgttaac gatttctctg catcccagtt     31440
     acttcggtcc tagaatgcag gactatttaa aggcaaaatt gttggcggac gtggaaggca     31500
     catgctcagg tcaatatggc tatataattt gcgttttgga cagtaatact atagatattg     31560
     ataaagggag ggtagttcct gggcaagggt ttgccgaatt tgaggtaaag tatcgtgcag     31620
     tgttatggag accatttcgt ggggaagtgg tcgatgcaat tgttacaaca gtaaataaaa     31680
     tgggattctt cgcaaatata ggaccattaa atgtctttgt ctcatctcat ttggtgcctc     31740
     cagatatgaa gtttgaccct actgcaaacc ctcctaatta ttctggtgag gatcaagtta     31800
     ttgaaaaggg gt                                                         31812
//