ID SPAPYUK71 standard; DNA; FUN; 8821 BP. XX AC AL109734; XX SV AL109734.1 XX DT 03-AUG-1999 (Rel. 60, Created) DT 29-NOV-1999 (Rel. 61, Last updated, Version 3) XX DE S.pombe chromosome I plasmid pYUK71. XX KW C2 domain family; calcium-transporting ATPase; eft1; eft2; KW elongation factor 2; RNA polymerase II subunit; rpb7. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-8821 RA Stevens K., Churcher C., McDougall R., Rajandream M.A., Barrell B.G.; RT ; RL Submitted (02-AUG-1999) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk XX DR GOA; O14072; O14072. DR GOA; O14459; O14459. DR GOA; O14460; O14460. DR SWISS-PROT; O14072; ATC4_SCHPO. DR SWISS-PROT; O14459; RPB7_SCHPO. DR SWISS-PROT; O14460; EF2_SCHPO. DR SWISS-PROT; Q9UT00; YKH3_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid pYUK71 is overlapped at the 5' end by cosmid SPUNK4. XX FH Key Location/Qualifiers FH FT source 1..8821 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid pYUK71" FT /map="IL" FT CDS 1..374 FT /codon_start=3 FT /db_xref="GOA:O14072" FT /db_xref="SWISS-PROT:O14072" FT /label=SPAPYUK71.01 FT /note="SPAPYUK71.01, len:123, SIMILARITY:Saccharomyces FT cerevisiae, ATC6_YEAST, probable calcium-transporting FT atpase 6, (1215 aa), fasta scores: opt: 450, E():4.8e-25, FT (53.8% identity in 117 aa)" FT /partial FT /gene="SPAPYUK71.01" FT /product="probable calcium-transporting ATPase 6" FT /gene="SPACUNK4.07c" FT /protein_id="CAB52144.1" FT /translation="LEKVDLEETFKPSLLNTAIYLLQLIQQVSTFAINYQGRPFREALS FT ENKGMYYGLLGIAFVAIAGVTEFSPELNAKLQLVKMAYNFQIQLLATMVVDYAACWIIE FT ELMKKYFRDNKPKEIVLRN" FT misc_feature complement(1..1391) FT /note="nominal overlap with SPUNK4, EM:AL031180 S. pombe FT chromosome 1" FT CDS join(968..1441,1509..1553) FT /db_xref="GOA:O14459" FT /db_xref="SWISS-PROT:O14459" FT /label=rpb7+ FT /note="SPAPYUK71.02, len:172" FT /gene="SPAPYUK71.02" FT /product="RNA polymerase II subunit rpb7" FT /gene="rpb7" FT /gene="SPAC2UNK4.06c" FT /protein_id="CAB52145.1" FT /translation="MPFFLKELSLTISLHPSYFGPRMQDYLKAKLLADVEGTCSGQYGY FT IICVLDSNTIDIDKGRVVPGQGFAEFEVKYRAVLWRPFRGEVVDAIVTTVNKMGFFANI FT GPLNVFVSSHLVPPDMKFDPTANPPNYSGEDQVIEKGSNVRLKIVGTRTDATEIFAIAT FT MKEDYLGVL" FT misc_feature 1208..1444 FT /note="Match to PF00575 S1, S1 RNA binding domain Score FT 34.67" FT misc_feature 1442..1447 FT /note="gtaagt, splice donor sequence" FT intron 1442..1508 FT /note="confirmed intron" FT misc_feature 1493..1508 FT /note="ctaacataatatctag, splice branch and acceptor" FT CDS complement(2049..5726) FT /db_xref="SWISS-PROT:Q9UT00" FT /label=SPAPYUK71.03c FT /note="SPAPYUK71.03c, len:1225, SIMILARITY:Saccharomyces FT cerevisiae, YNI7_YEAST, hypothetical 132.5 kd protein in FT top2-mkt1 intergenic region., (1178 aa), fasta scores: opt: FT 1406, E():0, (26.1% identity in 1098 aa)" FT /gene="SPAPYUK71.03c" FT /product="putative C2 domain family protein" FT /protein_id="CAB52146.1" FT /translation="MSSQAEPSKGASNADPNEKVEKMHLPTDTAGGGVKVKVKEQEASP FT SDKNNLNPQSAGVSEVQVQDDTGARGSGARDLKVPKQMQAPKSSEEKSDVDGVPTRPVS FT ERELRKRDAMQFIQRHQKVRNILAQYCPWLTDERLQLCIELKILFMQHFQDSRLVLYTA FT VMSFLFGYLRFGFLSLFIIMAVCIQYYRICDRRVKVNFKDDYTRYLSTRKLENDSETVT FT WLNTFLQQFWYIFEPSLSERITEITDQILSENVPSFIDSMALSEFTLGTKSPRMGFIRS FT YPKTEEDTVMMDLRLAFSPNDISDLTGREIAACIKPKIALDLKIGKSIASAKMPVLIED FT LSFTGNLRVKVKLIDKYPYAKTVGLTFTEKPVFSYILKPLGGDKFGFDIGNIPGLTTFI FT TEQIHNTLGPMMYSPNVYELDIESMMGAAGLNTALGAVEFKLRKGDGFKDGLGGAVDPY FT VVIKNSADRVIGKSKVAHNTGSPVFNETFYSVLNSFSENLNLEVYDFNDIRSDKLLGSA FT VLPLATLEAMPVTNDAFVELTLKGKTVGRLNYDMKFHAVVPDSGEEITKVDGPGVLQFT FT VHQCKELSNDPSKRPTAYAKLIINNKEVYTTRKIKKNNNPSWEESFGTLLPEGKNATLG FT VQIFTEESEHPFGTANVSLQDLFAATKTGLLWFPLQHAPSGRVRMSVMWKPAQLNNDSI FT SSMALATPIGAIRIHLRSANNLHSKIPGKKCDSYARIMSHNTKQFRTVVIASNVNPFWD FT EYMYAPVITKHDIFFLQVMNYNSSGEDKLIGQTPINISNFINQGENGALMEYHDPRELT FT VPLSSTRGIKGNATITFKCDFFPSAVTTSLSPDVTPAPKASSTVATDKVNIEVLPESQK FT TPTAVDNTSTSRGSTSVKTSKPKKISELLMPSEAVNAALDFESGFMGFDIISYKIAKPA FT QELAIFLDDLPHHIFLSSALNVTGGATLHEYGNTFIRQLEYSQCTFKLLDGDKEVGSKT FT MLSRDLISKGATKPLEIAFPDGASILVAFRLTPVPVKLEEVEMYENMGEMTVDVIKATD FT LPAADSNGKSDPFVVFELQGEEVYRTKTHKRTLNPTFNESFEVELPCKQTCNFVANVFD FT WDFGNKDDHLGSCVIDCKLLQQQQQTNYEIPLDSKQGVLYLRITLSPKWVLRSKRAGNS FT SLVEGILGQTASIVGMPLKGISTVGNVAVDGVASVANLTNKMRKGISRGFKGIHHEKAK FT " FT misc_feature complement(2364..2609) FT /note="Match to PF00168 C2, C2 domain Score 83.57" FT misc_feature complement(3369..3611) FT /note="Match to PF00168 C2, C2 domain Score 20.01" FT misc_feature complement(4173..4406) FT /note="Match to PF00168 C2, C2 domain Score 25.32" FT CDS complement(6381..8821) FT /codon_start=3 FT /db_xref="GOA:O14460" FT /db_xref="SWISS-PROT:O14460" FT /label=eft2 FT /note="SPAPYUK71.04c, len:812" FT /partial FT /gene="eft2" FT /gene="SPAPYUK71.04c" FT /product="elongation factor 2" FT /gene="SPAC513.01c" FT /protein_id="CAB52147.1" FT /translation="GKSTLTDSLVQKAGIISAAKAGDARFMDTRADEQERGVTIKSTAI FT SLFAEMTDDDMKDMKEPADGTDFLVNLIDSPGHVDFSSEVTAALRVTDGALVVVDTIEG FT VCVQTETVLRQALGERIRPVVVVNKVDRALLELQISQEELYQNFARVVESVNVVISTYY FT DKVLGDCQVFPDKGTVAFASGLHGWAFTVRQFANRYAKKFGIDRNKMMQRLWGENYFNP FT KTKKWSKSATDANGNSNQRAFNMFILDPIYRIFDAVMNSRKDEVFTLLSKLEVTIKPDE FT KELEGKALLKVVMRKFLPAADALMEMIVLHLPSPKTAQQYRAETLYEGPMDDECAVGIR FT NCDANAPLMIYVSKMVPTSDRGRFYAFGRVFSGTVRSGLKVRIQGPNYVPGKKDDLFIK FT AIQRTVLMMGSRIEPIEDCPAGNIIGLVGVDQFLVKSGTLTTSEVAHNMKVMKFSVSPV FT VQVAVEVKNGNDLPKLVEGLKRLSKSDPCVLCTTSESGEHIVAGAGELHLEICLKDLQE FT DHAGIPLKISPPVVSYRESVSEPSSMTALSKSPNKHNRIFMTAEPMSEELSVAIETGHV FT NPRDDFKVRARIMADEFGWDVTDARKIWCFGPDTTGANVVVDQTKAVAYLNEIKDSVVA FT AFAWASKEGPMFEENLRSCRFNILDVVLHADAIHRGGGQIIPTARRVVYASTLLASPII FT QEPVFLVEIQVSENAMGGIYSVLNKKRGHVFSEEQRVGTPLYNIKAYLPVNESFGFTGE FT LRQATAGQAFPQLVFDHWSPMSGDPLDPTSKPGQIVCEARKRKGLKENVPDYTEYYDRL FT " FT misc_feature complement(6486..7001) FT /note="Match to PF00679 EFG_C, Elongation factor G FT C-terminus Score 227.11" FT misc_feature complement(7206..8819) FT /note="Match to PF00009 GTP_EFTU, Elongation factor Tu FT family Score 618.95" FT misc_feature 8720..8821 FT /note="nominal overlap with cosmid SPAC513, EM:AL122032 S. FT pombe chromosome 1" XX SQ Sequence 8821 BP; 2793 A; 1769 C; 1752 G; 2507 T; 0 other; ctttagaaaa ggtggattta gaagaaacct tcaagccttc tttgttgaat actgccattt 60 atttgcttca acttattcaa caagtctcaa cgtttgctat caattatcag ggccgtcctt 120 tccgtgaagc tttaagtgaa aataaaggaa tgtactatgg ccttttgggc attgcctttg 180 tcgctattgc tggtgtaact gagttttcgc ctgaactcaa cgcaaaactt cagttagtta 240 aaatggctta taatttccag atacaactgt tagccacaat ggttgtagat tacgcggctt 300 gttggattat tgaagagctt atgaaaaaat acttccgtga caacaagccg aaggaaattg 360 ttcttcgtaa ttaagaacaa ttatataagt gggttacacc tacttatctg tacaagctta 420 gataaatatt catttgaaca aactgatgag taattgcatt actcactgat gggcaaggat 480 gtcaattttc ttcggtcagt atacaatatt tatcaccatt ttcaatttga ttacttgtta 540 tgaatatttt acatagactc aatgattgat tcattcttgg catatttgat ttattaattt 600 ggaatagtgt aagtgagctt tttataggac gtaatagatg cttattagag ataaaataat 660 attcacttgt taaaatcctt ctcagtagca aggtgaaagg catataaaat ttgggatatt 720 tctataagcg ctatcccatg atactgggac ttcgtaaatc ctcgaacgct cagcatatat 780 caagcaattg cgaaaaccgc tgaaaaattg ggataattta atttaataaa aagagctaag 840 ctcatttaaa gttttttttt ttaatgttca tcatttttgc cctattttga accaaaattt 900 tacagtttta atacgcatcg accgatcgag ttgaattggg gcttttctgc attaacttat 960 cgatacaatg cctttcttcc tcaaagagct ttcgttaacg atttctctgc atcccagtta 1020 cttcggtcct agaatgcagg actatttaaa ggcaaaattg ttggcggacg tggaaggcac 1080 atgctcaggt caatatggct atataatttg cgttttggac agtaatacta tagatattga 1140 taaagggagg gtagttcctg ggcaagggtt tgccgaattt gaggtaaagt atcgtgcagt 1200 gttatggaga ccatttcgtg gggaagtggt cgatgcaatt gttacaacag taaataaaat 1260 gggattcttc gcaaatatag gaccattaaa tgtctttgtc tcatctcatt tggtgcctcc 1320 agatatgaag tttgacccta ctgcaaaccc tcctaattat tctggtgagg atcaagttat 1380 tgaaaagggg tcgaatgtca gacttaagat tgtcggtaca aggactgatg caaccgaaat 1440 tgtaagtttc ccaatagttc acaatattta ttttgcttaa ttaatcgtgt tactaacata 1500 atatctagtt tgccattgca acaatgaaag aggattatct aggcgttctt taaaaagata 1560 aaattttaat ttgtctttta tttctcatgt tcattaattc aatgctaacc atcgcgtata 1620 ctgttattat taagttcctt tctaggtctc aaagtttatt catgtagttg taaaagcgca 1680 taccaacgtt tatcgatcta aattttggct ctattctgtg gtaatgttat ggctaaaagc 1740 tgcgcaatat ctttaaaaaa aaattttaac tttatatacc ctttacacaa caatagaatt 1800 tccctaatta ttgtatataa tcgcaatatc aatcgacgat ttccttatga atacaatctt 1860 gggctagcat tttatctatt aggagtgcat aagtctttat cgttcttcgg taaatagaaa 1920 accatgaaaa tattcaaata ccttataatc aaagtatgca tttaacataa tgataatata 1980 ttactcaaat aagtcagaat gcgaaaaccg aattgtaata aagaactaat aaataacaga 2040 atggaaagtc actttgcctt ctcgtgatga attcctttaa aaccacggct tattcctttt 2100 cgcattttgt tcgtaaggtt agccaccgag gcaaccccat caacagcaac attacctaca 2160 gtactaatgc ctttaagagg cataccaaca atcgaagcag tctgtccaag aattccttcg 2220 acaagagaag aatttccggc gcgtttggaa cgaaggaccc attttgggct cagagttata 2280 cgaagataaa gaactccttg tttgctatcc aaaggaattt catagttagt ctgttgttgc 2340 tgttgaagaa gcttgcagtc gattacacaa gagcccaaat gatcgtcctt gttaccaaaa 2400 tcccaatcaa aaacattagc aacaaaatta caggtttgct tgcaaggaag ttcgacctcg 2460 aaactttcat taaaagtagg atttaacgtc cgcttgtgcg ttttagtccg gtacacttct 2520 tctccttgca actcgaaaac aacgaaagga tcagactttc cattggaatc tgcggcaggg 2580 agatccgtgg cttttatgac atcgacggtc atttctccca tattttcgta catttcaact 2640 tcctcaagtt tcacaggaac aggagttagc ctaaaagcga ccaaaatcga agcaccatca 2700 ggaaatgcaa tttccagagg tttagtagcg cctttactaa ttaaatcgcg actcagcata 2760 gttttgctac caacctcctt atcaccatct agcagcttga aagtacattg agaatattca 2820 agttgtctga tgaaagtatt gccgtactca tgcagggtag caccaccggt gacgtttaag 2880 gcagatgata agaaaatatg atgaggtaaa tcgtctaaaa atatagctaa ctcttgggct 2940 ggcttagcta ttttatacga aattatgtcg aaacccatga agccagattc aaagtctaaa 3000 gctgcattta cagcttcaga cggcataagc agttctgaaa tcttctttgg ttttgaggtt 3060 ttaacagacg tagaccctcg agaagttgaa gtgttgtcga ctgctgtagg cgttttttgg 3120 ctttccggaa gcacttcgat atttacttta tcagttgcaa cagttgatga agctttagga 3180 gcgggtgtca catcagggct gagcgaggtt gtgacagcgg atgggaaaaa gtcacatttg 3240 aaagttattg ttgcattacc ctttataccc cgggtagagg acaaaggtac agttagttct 3300 cgagggtcat ggtattccat taaagcacca ttttcgcctt gattgataaa atttgatatg 3360 ttgatagggg tctgtccaat gagtttgtct tcaccagatg aattgtaatt catcacttgt 3420 aaaaagaaga tgtcatgttt ggtaattacg ggtgcataca tgtattcatc ccaaaacgga 3480 tttacattgc tagcaatgac cactgtccta aactgtttcg tattgtggga catgatgcgt 3540 gcgtaagaat cacatttttt accaggaatc ttagagtgca aattattcgc cgaacgtaaa 3600 tggatacgaa ttgcaccgat gggagtagca agagccatcg aagaaatact gtcgttattt 3660 aactgagcag gtttccacat aacagacata cgtactctac cggatggagc atgttgtaat 3720 ggaaaccata aaagacccgt cttagtagca gcaaacaagt cctgcaaaga tacattagcg 3780 gtcccaaaag gatgctctga ttcctccgtg aatatttgaa cacccagagt agcattcttc 3840 ccttctggaa gaagagtacc aaaggattct tcccatgatg gattattgtt tttcttaatc 3900 tttctggtcg tatagacttc tttattgtta ataatcaatt tggcataagc ggtaggtcgt 3960 ttcgatggat cattgctaag ctctttgcat tgatgcacag taaattgcag aacaccaggg 4020 ccatcgactt tagtaatttc ttcgccagaa tcaggcacaa ctgcatggaa tttcatgtca 4080 taatttaaac gaccaacagt cttgcctttt aaagtcaatt ctacaaacgc atcatttgtc 4140 acaggcatag cttccagagt agctaatggt agtacagcac tgcccagaag tttgtcactt 4200 cgaatatcgt taaaatcata tacctccaaa ttcaggttct ctgaaaacga attcaaaacg 4260 gaataaaaag tttcgttgaa taccggcgaa ccagtgttgt gagccacttt agatttacca 4320 ataacacgat ccgctgaatt ttttataaca acatatggat caacagctcc acctaaaccg 4380 tctttaaaac catctccctt gcgtaactta aattctacgg ctccgagagc agtatttaag 4440 ccagcggcac ccatcataga ttcgatatcc agctcataca cattgggact gtacatcatt 4500 gggcccaacg tgttatgtat ctgttcggtg ataaacgtag taagacccgg aatgttgcca 4560 atatcaaaac caaacttatc acctccgaga ggtttaagaa tgtaagagaa aacaggtttc 4620 tcggtaaaag tcaaaccgac agtcttggca tacgggtatt tatcaataag ctttacttta 4680 acacgaaggt taccagtgaa ggaaaggtcc tcaattaaaa caggcatttt agctgaagca 4740 atactttttc ctattttcaa atcaagagca atcttaggtt tgatgcaagc agcaatctca 4800 cgacccgtta agtcactaat atcatttgga ctaaatgcta atctcaaatc catcataaca 4860 gtgtcttcct ctgttttagg gtaactacgg ataaatccca ttctcggtga tttggttccc 4920 agagtaaatt cggagagagc catggagtca ataaagctgg ggacattttc tgaaagaatc 4980 tgatccgtaa tttccgttat tctctcactt aaagaaggtt caaaaatata ccaaaattgt 5040 tgtaaaaagg tgtttagcca agtgacagtt tcgctatcat tttctaattt tcgtgtagaa 5100 agatatctcg tatagtcgtc tttgaaattg actttaacac gtcgatcgca aattcggtag 5160 tactggatac aaacagccat aataatgaaa agactcaaaa atccgaagcg caaataacca 5220 aacaaaaatg acatgactgc cgtatacaaa acaagccttg aatcctggaa atgttgcata 5280 aagagaattt taagctcaat gcataattgt aaacgttcat cagtcagcca aggacagtat 5340 tgtgccaaaa tgttcctaac cttttggtgc ctttgaatga attgcatcgc atcccttttc 5400 cttaattccc tctcgctaac aggacgagtg ggcactccat caacgtctga tttctcttca 5460 gatgatttgg gtgcttgcat ttgtttaggg acctttaagt ctctagcacc tgagccacgg 5520 gctccagtat catcctgtac ttgaacctca gaaactccag ctgattgtgg gtttaagtta 5580 ttcttgtctg atggtgaagc ttcttgttcc ttaactttca ccttaacacc accaccagct 5640 gtatcagtag gaagatgcat tttttcaacc ttttcattcg ggtcggcatt gctagcaccc 5700 ttagagggct cagcctgcga agacattgtt tctgcttaaa caatcaaaat aaggtgtagt 5760 ttctgcttta tataaataac tggttaatcc gataaccaaa aaataaatag tttccgtaat 5820 taataaatat tgctagacca aaagagaacg aatagtcaaa aaaaaaaagg tcttatcact 5880 gcttggttcg tgacagatgt tggagattaa agtcacagtg tataactggc tgtcataatg 5940 aatcaagagt acaccaatat ctggccagtt ttactttccc ttaagattcc ttaaaataag 6000 ttggagtttt tggcgctaca cagaacggcg tttaaattca gtaacaggat ttagcataac 6060 aaatagggcg cccttgttaa gttatataat cggtctcata ttgaaacact gtagaataat 6120 agtagtgtcg aaagcggatt gaaaactaaa tatgaaacga cttccttgcg attttcataa 6180 ttataggtgt attttacaca agaaacgttt atctacagga ttgccgagta ttttataaag 6240 gtttaagttt attaattcac atttttttag ctaatcaacg ctacaaaatt aacgcaaggc 6300 taaaaatcct caacacagct gattaagaat cgagttttta aataacctgt attaaatagt 6360 aaaaaccaaa actatatact ttaaaggcgg tcataatatt cagtgtagtc gggaacattt 6420 tccttaagac ccttacgctt acgagcttcg caaacaattt gaccaggttt agaagtagga 6480 tccaatggat caccagacat gggagaccaa tggtcaaata ccaattgagg gaaagcttga 6540 ccagcagtag cttgacgaag ttcaccagtg aaaccgaaag actcgttgac gggaaggtaa 6600 gccttgatgt tgtacaaggg agtaccaaca cgttgctcct cagaaaagac atgaccacgc 6660 ttcttgttaa ggacagagta aataccaccc atagcgtttt cggaaacttg gatttcgacc 6720 aagaaaacgg gctcctggat gatgggagaa gccaaaaggg tagaagcgta gacgacacga 6780 cgagcagtag gaataatttg accaccacca cggtgaatag catcagcgtg caaaacaaca 6840 tcaagaatgt tgaaacggca agaacgcaag ttctcctcaa acatgggacc ctccttggaa 6900 gcccaggcaa aagcagcaac aacggaatcc ttgatttcgt ttaagtaagc aacagccttg 6960 gtttgatcaa caacaacatt ggcaccagtg gtgtcaggac cgaaacacca aatcttacga 7020 gcatcagtga catcccatcc aaactcgtca gccatgatac gagcacgaac cttgaaatca 7080 tcacgaggat tgacgtgacc agtctcaatg gcgacagaga gttcttcact catgggctca 7140 gcagtcatga agatacggtt gtgcttgttg ggagacttag agagagcagt catgctagag 7200 ggctcgctaa cggactcacg gtaagaaacg acgggaggag aaatcttaag agggatacca 7260 gcatggtctt cttgcaaatc cttcaagcaa atctccaagt ggagctcacc agcaccagca 7320 acaatgtgtt caccagattc actggtggta cacaaaacac aagggtcgga tttggaaaga 7380 cgcttaagac cttcaacaag tttaggcaaa tcattaccgt tcttaacctc aacagcgact 7440 tggacgactg gggagacgga aaacttcata accttcatgt tgtgggcaac ttcggaagtg 7500 gtcaaagtac cagatttgac caaaaattga tcaacaccga ccaaaccaat aatgttacca 7560 gcaggacaat cctcaatagg ctcaattctg gaacccatca taaggacggt acgttggata 7620 gccttgatga agagatcgtc cttcttaccg ggaacatagt tagggccttg aatgcggacc 7680 ttcaaaccag aacggacagt accggagaag acacgaccaa aagcatagaa acgaccacga 7740 tcagatgtgg gaaccatctt agaaacgtag atcataagag gagcattggc atcacagtta 7800 cggataccaa cagcacactc gtcgtccatg ggaccttcat acaaagtctc agcacgatat 7860 tgttgagcag tcttaggaga aggaagatga aggacaatca tttccataag ggcatcagca 7920 gcaggcaaga acttgcgcat aacgaccttc aagagagcct taccctcaag ctccttctca 7980 tcgggcttga tggtaacctc gagcttactc aaaagagtga agacctcgtc tttgcggctg 8040 ttcataacag catcgaaaat acgataaatg ggatccaaga tgaacatgtt gaaagcacgt 8100 tggttagagt taccgttagc atcggtagca gacttggacc atttcttggt cttagggttg 8160 aagtagtttt caccccaaag acgttgcatc atcttgttac ggtcaatacc aaacttctta 8220 gcataacggt tggcaaattg acggacagtg aaagcccaac catgaagacc ggaagcaaaa 8280 gctacagtac ccttgtcagg gaaaacttgg cagtcgccaa ggaccttgtc gtaataagta 8340 gaaataacga cgttaacaga ttcaacgaca cgagcaaaat tttgataaag ctcttcttga 8400 gaaatttgaa gttcgagcaa agcacggtca actttgttaa caacaacaac tggtctaata 8460 cgttcaccca aagcttgacg gagcacagtc tcggtttgga cacagacacc ctcaatggta 8520 tcaacaacga ccaaagcacc gtcagtgaca cgaagagcgg cagtaacctc agaagaaaag 8580 tcaacgtgac cgggagagtc aatcaagtta accaagaagt cagtaccatc agcaggctcc 8640 ttcatatcct tcatatcatc gtcagtcatt tcagcaaaca aggaaatggc agtagacttg 8700 atggtaacac cacgctcttg ttcgtcagca cgagtatcca tgaaacgagc atcaccagcc 8760 ttggcagcag aaataatacc ggccttttga accaaagaat cagtcaacgt agacttgccg 8820 t 8821 //