ID SPAP7G5 standard; DNA; FUN; 23037 BP. XX AC AL353014; XX SV AL353014.1 XX DT 19-APR-2000 (Rel. 63, Created) DT 19-APR-2000 (Rel. 63, Last updated, Version 1) XX DE S.pombe chromosome I plasmid p7G5. XX KW 60s ribosomal protein l10; amino-acid permease; KW aminoadipate-semialdehyde dehydrogenase; coiled-coil protein; KW confirmed intron; GMP synthase [glutamine-hydrolyzing]; KW low complexity gene free region; lys1; rpl10-2; transfer RNA; KW tRNA Arg anticodon ACG; tRNA Phe anticodon GAA. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-23037 RA Barrell B.G., Rajandream M.A., Saunders D., Wood V., Harris D.; RT ; RL Submitted (19-APR-2000) to the EMBL/GenBank/DDBJ databases. RL Schizosaccharomyces pombe chromosome I sequencing project, Sanger Centre, RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: RL barrell@sanger.ac.uk XX DR GOA; P40976; P40976. DR GOA; Q9P768; Q9P768. DR GOA; Q9P769; Q9P769. DR GOA; Q9P772; Q9P772. DR SPTREMBL; Q9P768; Q9P768. DR SPTREMBL; Q9P771; Q9P771. DR SPTREMBL; Q9P772; Q9P772. DR SPTREMBL; Q9P773; Q9P773. DR SWISS-PROT; P40976; LYS2_SCHPO. DR SWISS-PROT; Q9P769; RL1B_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPAC5H10.01c. CC SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Plasmid p7G5 is overlapped at its 5' end by cosmid SPAC15E1. XX FH Key Location/Qualifiers FH FT source 1..23037 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid p7G5" FT /map="I" FT misc_feature 1..96 FT /note="nominal overlap with cosmid SPAC15E1 S. pombe FT chromosome 1" FT CDS 1..611 FT /codon_start=3 FT /db_xref="SPTREMBL:Q9P773" FT /label=SPAP7G5.01 FT /note="SPAP7G5.01, len:>202aa" FT /partial FT /gene="SPAP7G5.01" FT /gene="SPAC15E1.10" FT /product="hypothetical protein" FT /protein_id="CAB88268.1" FT /translation="RLIFWNKWIYILCANTSSNITATRIFRLDDDQPWNLESLVAEVCP FT VDTDNRLAEHAARTAKDTSANELNYESYQEKSRAPFGFAGPFGAMPGSQPMFPSIGASD FT LYPAGIGGSDMGNDGGMIPTFNHPIFHPENRSRNEQASANRTNIPPGARYDPTGPGDFR FT GFGRDERKPQFPFKGPRSQFPGEPDNDDFMPPGSSDMFM" FT CDS join(complement(2932..2970),complement(2848..2888), FT complement(1108..2647)) FT /db_xref="GOA:Q9P772" FT /db_xref="SPTREMBL:Q9P772" FT /label=SPAP7G5.02c FT /note="SPAP7G5.02c, len:540, SIMILARITY:Saccharomyces FT cerevisiae, GUAA_YEAST, gmp synthase FT [glutamine-hydrolyzing], (524 aa), fasta scores: opt: 2470, FT E():0, (71.0% identity in 527 aa)" FT /gene="SPAP7G5.02c" FT /product="GMP synthase [glutamine-hydrolyzing]" FT /protein_id="CAB88269.1" FT /translation="MSSTEVPGEVSTSVSSYFDTILILDFGSQYSHLIARRLREIHVYA FT ELLPCTQKIEALPFKPIGVILSGGPYSVYDDIAPHVDPAVFELGVPVLGICYGMQEIAW FT LNGRCVEPGIEREYGPATVSMEPEIKTEVFKSFFNSMPKEFEVWMSHGDRLSALPNGYE FT TIGRTKNSPFAVIAHVTKPIIGLQFHPEVTHTPLGLQLIKNFAIEICHAKPNWSMENFV FT DKEILRIRKMIGPSDHVIGAVSGGVDSTVASKVLKEAIGDRFHAIMVDNGLLRLNEAEI FT VRETLNKHLGIQLTVVDASEEFIGKLKGVTDPEKKRKIIGNTFIHVFEREAERIVKETN FT GKVEYLLQGTLYPDVIESISFKGPSQTIKTHHNVGGLLKDMKLKLIEPLRELFKDEVRA FT LGELLGIEHSLVWRHPFPGPGLGIRILGEVNAAQLEIARKADHIFITEIRNHGYYDKIS FT QAFAALLPVKAVGVMGDKRTHEQVIALRAITTSDFMTADWYDGFSIKFLKLVSSRICNE FT VSGVNRVLYDISSKPPATVEME" FT misc_feature complement(1111..1422) FT /note="Match to PF00958 GMP_synt_C, GMP synthase C terminal FT domain Score 174.01" FT misc_feature complement(2101..2646) FT /note="Match to PF00117 GATase, Glutamine amidotransferase FT class-I Score 133.81" FT misc_feature complement(2648..2663) FT /note="ctaaccataattgtag, splice branch and acceptor" FT intron complement(2648..2847) FT /note="confirmed intron" FT misc_feature complement(2842..2847) FT /note="gtacgt, splice donor sequence" FT misc_feature complement(2889..2906) FT /note="ctgatctgaatatcaaag, splice branch and acceptor" FT intron complement(2889..2931) FT /note="confirmed intron" FT misc_feature complement(2926..2931) FT /note="gtaagt, splice donor sequence" FT tRNA 3891..3963 FT /note="tRNA Arg anticodon ACG, Cove score 75.46" FT CDS join(4326..5835,5876..6477) FT /db_xref="SPTREMBL:Q9P771" FT /label=SPAP7G5.03 FT /note="SPAP7G5.03, len:704, predicted to contain FT coiled-coil region, SIMILARITY:Saccharomyces cerevisiae, FT YN19_YEAST, hypothetical 73.4 kd protein in erg24-met2 FT intrgenic region., (661 aa), fasta scores: opt: 274, FT E():7.3e-10, (24.8% identity in 646 aa)" FT /gene="SPAP7G5.03" FT /product="hypothetical coiled-coil protein" FT /protein_id="CAB88270.1" FT /translation="MASSYLSLAARLSQCWISPWSLCCLYILMQFFLFTKDLNTKIGDF FT VNDEQATCNYIQEKVDILLDSPSLIANAAVRVAKDGIQSTVKIILSGISDSLIAAENVF FT IFFIEFSYGTYLCLIQLAIDGILDAVADVGEEIGTAVNDTLHAIADEIEDTVSSLNEVF FT QSAEDSLEKVASWLGEDINLPNVSIPEIQSLRNFTLSSSYDTEFEKLKAGVNFDSAINA FT TKAAISKPFSSARNLILEKVSNYSFDTSMVSSPNKTHVVVCSTDDLTAISSFILSSIYK FT IRKVVIISLLIIIAGLFLISSIYEIWKWCRIRHKAFLLDEHIRSNKFEDTRDLISYIES FT PISWNLKYFISALPLPCFLSVQLRWFITYIFHPPAAMILFISCTSFISGILQLVLLNNI FT REDGSVISALAQNSFHKVESALANVSVAWANSTNQIILKNQENINNNMFGSIHNTTLSL FT NSTLNTFMNELNSSMTSAFGDTFLASTVQNVMNCLLYRKIENFEEVLTWVYNKSHIELP FT LLPTDILSKSIDNQTIYSSLYSSLNSSNSTVSFSGIFDRVEKSVISELNFSFLFFLLWL FT LICAFGLIGVLSSWLKSLFLSLLDLVIPNPKENITLPVQSLAFPVTKSCRPPPIPPRES FT HVYDFQNFQYEEDDCIDYKRSLGLISLSSDLAIDIPISPAIISDIQFNSITTESEETTY FT LLKEKQDRY" FT misc_feature 5836..5841 FT /note="gtttgt, splice donor sequence" FT misc_feature 5865..5875 FT /note="ctaaccaatag, splice branch and acceptor" FT CDS complement(6533..10792) FT /db_xref="GOA:P40976" FT /db_xref="SWISS-PROT:P40976" FT /label=lys1 FT /note="SPAP7G5.04c, len:1420" FT /gene="lys1" FT /gene="SPAP7G5.04c" FT /product="aminoadipate-semialdehyde dehydrogenase" FT /protein_id="CAB88271.1" FT /translation="MSQTAPSDTEYNQRLERWSERLKSQTISHLPTDYSRPVPSRLVEA FT VFERTLPEDAKTALIKVYVAAQAKGILVTPFNILLTIFIILVSRMTGDEDISIGTSSEN FT AIPFVLRTFIQPSDSFLDLLAKVCDLEKEGSSDAVDFSDLINFLNAKLSKKDDPRKTLV FT HLRFYNAPDAPSENFLSTTGLDVDLTVLVSVKKPSDQLTSLRSQFTFPDLQLKLIYNQL FT LFSESRVNIVADQLLKLVVSASKDVTGPIGALDLMTPTQMNVLPDPTVDLDWSGYRGAI FT QDIFASNAAKFPDRECIVVTPSVTIDAPVTSYTYRQIDESSNILAHHLVKNGIERGDVV FT MVYAYRGVDLVVAVMGVLKAGATFSVIDPAYPPARQIIYLSVAKPRALVVLEDAGVLSP FT TVVEYVEKSLELKTYVPALKLAKDGSLTGGSVSKGADDILQHVLHLKSEQTGVVVGPDS FT TPTLSFTSGSEGIPKGVKGRHFSLAYYFDWMAQEFNLSESDRFTMLSGIAHDPIQRDIF FT TPLFLGASLIVPTAEDIGTPGQLAQWANKYKVTVTHLTPAMGQLLAAQADEPIPSLHHA FT FFVGDILTKRDCLRLQVLANNVNVVNMYGTTETQRSVSYFVVPARSQDQTFLESQKDVI FT PAGRGMKNVQLLVINRFDTNKICGIGEVGEIYLRAGGLAEGYLGNDELTSKKFLKSWFA FT DPSKFVDRTPENAPWKPYWFGIRDRMYRSGDLGRYLPTGNVECSGRADDQIKIRGFRIE FT LGEINTHLSRHPNVRENITLVRRDKDEEPTLVAYIVPQGLNKDDFDSATESEDIVVNGL FT KKYRKLIHDIREYLKTKLPSYAIPSVIVPLHKMPLNPNGKIDKPALPFPDTSQLAAASR FT SHSKHGVDETLTATERDIRDIWLRIIPHATDVNKKASFFDIGGHSILATRLIFELRKKF FT AVNVPLGLVFSEPTIEGLAKEIERMKSGEMISVMDIGKEETREPEIEYGKDALDLVDLI FT PKEFPTSKDLGIDEPKTVFLTGANGYLGVFILRDLMTRSSNLKVIALVRASSEEHGLKR FT LKDSCTAYGVWDESWAQKISVVNGDLALENWGIEERKWNKLTEVVDYVIHNGALVHWVY FT PYSKLRGPNVMGTITALKLCSLGKGKSLSFVSSTSTVDTEYYVNLSNEITSKGGNGIPE FT SDPLQGSSKDLHTGYGQSKWVSEYLVRQAGLRGLRGVVVRPGYILGDSKSGAINTDDFL FT VRMVKGCIELGLYPNINNTVNMVPADHVARVVTASAFHPEQGVIVAHVTSHPRLRFNQF FT LGTLSTFGFNTKLSEYVNWRIALERFVINESHDSALYPLLHFVLDNLPANTKAPELDDT FT NTREILKRDASWTNVDVSNGAAILEHEMGLYLSYLVAIGFLPKPTLEGKKLPEVKINEA FT TLEKLASAGGRGGAPTH" FT misc_feature complement(7937..8134) FT /note="Match to PF00550 pp-binding, Phosphopantetheine FT attachment site Score 68.38" FT misc_feature join(complement(8722..9853),complement(8486..8679)) FT /note="Match to PF00501 AMP-binding, AMP-binding enzyme FT Score 292.57" FT misc_feature 11535..12062 FT /note="Match to PF00826 Ribosomal_L10e, Ribosomal L10 Score FT 491.59" FT CDS 11535..12200 FT /db_xref="GOA:Q9P769" FT /db_xref="SWISS-PROT:Q9P769" FT /label=rpl10-2 FT /note="SPAP7G5.05, len:222" FT /gene="rpl10-2" FT /gene="SPAP7G5.05" FT /product="60s ribosomal protein l10" FT /protein_id="CAB88272.1" FT /translation="MARRPARCYRYCKNKPYPKSRYNRAVPDSKIRIFDLGRKRAGVDE FT FPLCIHLVSNEYEQITSEALEAARICANKYLVKIGGKDSFHLRVRAHPFHVVRINKMLS FT CAGADRLQTGMRHAFGKPNGLVARVNIGQVLMSVRTKDSSRATAIEALRRCQYKFPGQQ FT RIIVSKKWGFSQYARDEYIEKRSRGEIIPDGCYAKFLNKRGSLQEKLDLFPEASFNLA" FT misc_feature 12201..17065 FT /note="Low complexity gene free region" FT CDS 17066..18817 FT /db_xref="GOA:Q9P768" FT /db_xref="SPTREMBL:Q9P768" FT /label=SPAP7G5.06 FT /note="SPAP7G5.06, len:584, SIMILARITY:Schizosaccharomyces FT pombe, CAB60021, amino-acid permease, (537 aa), fasta FT scores: opt: 2739, E():0, (78.1% identity in 529 aa)" FT /gene="SPAP7G5.06" FT /product="amino-acid permease" FT /protein_id="CAB88273.1" FT /translation="MSSPDRSIDIDLEKYPSTATKSVYGQSKDDKNVFDIHPTESEVIP FT GEVEYADTPSHQNFLQKFFSDFKPVKADREDGVALKRHLKGRHMQMIAIGGAIGTGLFV FT GSGSSLADGGPASVIIDYTLIGIMMFFTVYALGELAVSYPVAGGFYNYAVRFIDPAWGF FT AVGWNYFMNYFVTFPLELTTCAITFRYWTDINSCAWITIFLVFVICINLFGVRGYGEVE FT FILSTLKVVATTGFIILAIIINCGGVPTDPRGYIGGKIIKNKPFRHSFKGFCSVFTTAG FT FSFSGTEVVGLAAAEAEDPQKSLPRATKQVFWRIAIFYVVSLILIGLLVSPDDPRLMGN FT SSDGSTSPFVLAIKEANIRGLPSVFNAVIIISTVSVANSCTFTASRTLHAMAAKGDAPR FT FFAYTDRLGRPLLAMAVCLLFGFFAYINAAGDVSDTVFDWLLAISGISNFFSWGSINLC FT HIVFRLAMKKQGRSLDQLGFVSPMGIWGSAIGLAFNILCLMAEFYVSLFPIGSKPNAND FT FFQGYLAAPIVIAFFIGYKIYDRSHIPSLSKLDLDTGLRTYPPKDKESEKIRDAKGFFK FT WIWQSLC" FT misc_feature 17303..18685 FT /note="Match to PF00324 aa_permeases, Amino acid permease FT Score 790.74" FT tRNA complement(19705..19777) FT /note="tRNA Phe anticodon GAA, Cove score 69.56" FT misc_RNA complement(20531..20860) FT /note="Schizosaccharomyces pombe late log phase cDNA FT Schizosaccharomyces pombe cDNA clone spc00798; not FT associated with an orf" FT misc_feature complement(20793..23037) FT /note="Chromosome I Centromeric repeat" XX SQ Sequence 23037 BP; 7093 A; 4287 C; 4058 G; 7599 T; 0 other; ctcgtttaat attttggaat aaatggattt atattttgtg tgctaatact tcatcaaata 60 tcacagctac aaggattttc cgtttagatg atgatcagcc ttggaatttg gaatctttag 120 ttgcagaggt ttgtccagtt gatacagata atcggcttgc tgaacatgct gcacgtaccg 180 ctaaagatac ctcggctaat gagttaaatt atgaatcata tcaggagaag agcagagctc 240 catttgggtt tgctggacca tttggtgcaa tgcctggctc acaaccaatg tttccttcta 300 taggagcaag tgatttgtat ccagcaggaa tcggaggatc tgatatgggc aacgatggag 360 gtatgattcc tacattcaat catcctattt ttcatcctga aaacaggtct cgaaatgaac 420 aagcttcagc aaaccgaact aatataccac caggagctcg ttacgatccc acaggccctg 480 gtgattttcg tggattcggc agggatgaga ggaaacctca atttcctttt aaaggcccgc 540 gatctcaatt tcccggtgaa cctgacaatg atgacttcat gccacctggt tcatccgata 600 tgtttatgta aattggtcac tttataagta ttacaagaaa tgttagatga taggatatgt 660 tatttaaata atagtaaaag attttggttt tgattttttt ttcttaatat gtgaatttta 720 atgctcaatt tcggaataaa cgcatactac tggatatctc tacttcttta aataattgag 780 ttttctacta tttgcgtaca aagtttagta agttcctctt ctaaagagcg catttataca 840 agtgttaaga atgaaaccag caggacctaa tgaaaacgtc tagtatttat tttcaatagg 900 acggtcttag caccgaattg ataatttcaa aacatacact cgggcacatg cctactcata 960 aattttttaa gctgttagat gtttattatt taacctcatc taaacttatt tactactacc 1020 tgccactaga atccaagaac taaacaaatt tctaaccaaa agtataaaag atgtaacaaa 1080 aggtaccgta tgctgttagg aacattatta ctccatttcg acagttgccg gaggcttact 1140 gctaatgtca tacaatacac gattaacacc agacacttcg ttgcaaatac gggagctgac 1200 caacttcaaa aacttaatgc taaacccatc gtaccaatca gctgtcataa aatcagaagt 1260 ggtaatagca cgaagagcaa ttacttgttc atgagtacgc ttgtcaccca taacaccgac 1320 agcctttacc ggtaaaagag cagcgaaagc ttgagaaatt ttatcataat agccgtggtt 1380 acgaatttca gtaataaaaa tgtggtcggc tttacgcgca atttcaagct gagcagcatt 1440 aacttcgcca aggatacgaa tgcccaaacc agggcctggg aaaggatgac gccagacaag 1500 gctatgttca ataccaagta attcacccaa agcacgaact tcgtctttga agagctcacg 1560 aaggggttca ataagtttga gcttcatgtc cttcaaaaga ccgccaacat tatggtgggt 1620 tttgattgtc tgagaagggc ccttgaaaga aatactttct atgacatcag gatataatgt 1680 tccctgcaat aagtattcaa ctttaccgtt ggtttcttta acaattcgct cagcctctcg 1740 ttcaaaaaca tgaataaacg tgttaccaat gatctttcgc ttcttctcgg gatcagtaac 1800 acctttcagt tttccaatga actcttcaga agcatcaact actgttaatt gaattcctaa 1860 atgcttattg agggtttcac gaacaatctc tgcttcatta agacgcagca agccattgtc 1920 aaccataatg gcatggaacc gatctccaat agcctctttc agaacctttg aagcaactgt 1980 tgaatctaca ccaccagaaa cagcaccaat gacatgatca cttggtccaa tcattttacg 2040 aatacgaaga atttctttat caacgaaatt ttccatactc cagttgggct tagcatggca 2100 gatttcaatg gcaaagttct taataagttg caaacctaat ggagtgtgag taacttcagg 2160 atggaattgc aaaccaatga tgggctttgt aacatgtgca atgacagcga aaggagaatt 2220 cttggtgcgt ccaattgttt catagccatt gggaagagcg cttagtctgt cgccatgaga 2280 catccaaacc tcaaattctt ttggcatgga gttaaaaaag cttttgaaga cctcggtttt 2340 gatttcaggt tccatactaa ctgtagctgg accgtactct ctctcgatac ctggttcaac 2400 acaacgtcca ttcaaccatg caatttcttg catgccataa caaataccga gtacaggaac 2460 accaagttca aagacagcag gatccacatg aggtgcaatg tcatcgtaaa cagaataggg 2520 gccgccagac aaaataacac caataggctt aaatgggaga gcttctattt tttgagtgca 2580 aggaagtaac tctgcataca cgtgaatctc acgaagacgt ctggcaatca aatgactata 2640 ctgagagcta caattatggt tagtacaaac gaatcaggaa gtcgaaaaga ccactactag 2700 agccattttt attttttatg agataaaaaa taggctcatt gaagaattga tcagagaaga 2760 gataaaaaat tcacaactaa tatatcacaa gcgcgaaact ccttcaatca caatcaaatt 2820 cattttaata taatttttaa aacgtaccca aagtcaagaa ttaaaatggt atcaaaatat 2880 gaagaaacct ttgatattca gatcagtaat gatgctaaca agcaaactta cagaagtaga 2940 gacttccccg ggcacttcag tggaactcat gatgagtaat taaaattaag tctcttttaa 3000 tctaatgaag ttggaatctt tatggcaact ggcaatgacc actggtaacc cctaaatggc 3060 acaaagtact agtatggtga agttgctaaa tccttgcgaa aaaaaatgta gccttttaaa 3120 gatagaccaa tgtaatgcgc atacactatt gtttataacg aattttagtg cagcaatgta 3180 tcgctcgtaa tatttcagat atctcctttt tcgatttctc catataatat aggaggtttt 3240 aaggtgaaaa ttcacttttc ggatgagtta taaagcactc atatatgata tttatgaaat 3300 ttttttatcc tcttatttta ctctttagct gtagtcttcg aattgtatca tagcctttct 3360 ctgccataaa tataagtttt cagaaaataa aatgataaaa aatatcaatt actcatttaa 3420 caagtggtag ccattgttat agcttttttt ttatatcttc tggccatgct cagtttatta 3480 ttattttttt tttcattgat ctgtgaactt gtgtatggtt gtttccattt tattacaatc 3540 catagagcat gcaggcaatt tcttaaaaat aatcgaactc cattcaatta aaagaatgtt 3600 tcagattctg ttctatcaga ataaattgct agttagctta taaaataagt acagttatat 3660 tttattattg actgctataa ctgctataac atgtatatgc agtaacattt ttaacattaa 3720 ataatgttga aaagtttata atatttaaga atcaatcaaa ttttggtaca taatattaaa 3780 acaatttact aaataaaaca taaaaataaa aaaaaagcaa aattatactt atttgcttaa 3840 ttaaaaagat aaaatataaa tttattatcg aagactgcaa tataatagca ggtctcgtgg 3900 cccaatggtt aaggcgcttg actacggatc aagagattcc aggttcgact cctggcggga 3960 tcgatttttt gaaatctaga aattcctagt ttatgtttgt ttaaatgcaa agctgtatga 4020 atatagatat tatcgatgcc ccttgtaatg cattgacaac tactttaatt gtctgttatt 4080 caactattac aggattcgca tatatatctg atttttctaa atactattat taacagttca 4140 acatgattgt tgtttttatt ttatgtttca tttaatgctg tttctaagcc atttacagtt 4200 tccacttctt ttatggtaat tctttgttta attctgagtt tctttgttct ttcgaaaatg 4260 tctaaacaaa gaaatgcaaa accgtctaac acatttatta caaggcagag atcgaacagc 4320 ctgtaatggc gtcttcatat cttagtttgg cagcgaggct ttcacagtgt tggatatcac 4380 cctggtcatt atgctgtctc tatattctca tgcagttttt cttatttacc aaggatttga 4440 acacaaaaat aggagatttt gtcaatgatg aacaagctac ttgtaactac atacaagaaa 4500 aagtcgacat tctccttgat agcccatcct taattgctaa tgcggctgtt agggttgcga 4560 aagatggcat tcaaagtaca gttaagatca ttctttctgg aatatcagac agtctcattg 4620 ctgctgaaaa tgtgtttatt ttctttatcg agtttagcta tggtacctat ctttgtctta 4680 ttcagctggc aatcgatggc atcttggatg cagttgctga tgtcggtgaa gagataggaa 4740 ctgcggtaaa tgatacattg catgcgattg cagatgaaat tgaagataca gtctcttctt 4800 taaacgaagt tttccaaagt gcagaagatt cgctggagaa agttgcctct tggctagggg 4860 aagacatcaa cctgccaaat gtctctattc ctgaaatcca gtctctccga aacttcactt 4920 tatcttcttc atatgataca gaatttgaga agttaaaggc tggtgttaat tttgatagtg 4980 ccattaatgc aacaaaagcg gccattagca aaccgttttc ttctgctcgg aatcttatcc 5040 ttgaaaaagt tagcaactat tcgtttgaca ctagtatggt ctcttctcca aataaaacac 5100 atgtagtggt ttgttcgact gatgatctga cggctatttc atcatttatt ctaagttcta 5160 tatataagat caggaaagtt gtcatcattt ctttgctaat tataattgcg ggattgtttt 5220 tgatttcttc gatttatgaa atttggaaat ggtgtagaat tagacacaaa gcatttcttc 5280 tggacgaaca cataagaagt aataaatttg aagatacccg tgacctaatt tcctatatag 5340 agtctcctat ttcctggaac ttaaaatatt ttatttcagc tcttccttta ccttgttttt 5400 taagtgtgca acttcgatgg ttcatcacat atatatttca tccccctgcc gcaatgattc 5460 tttttattag ttgcacttcc tttatttctg gcattctaca gctggtactt ctcaacaata 5520 ttcgtgaaga tggttcagta atcagtgctc tagcgcaaaa ttcatttcat aaagttgaat 5580 ctgctttagc aaatgtttca gtagcatggg ctaattcaac taaccaaatt attttaaaaa 5640 atcaagaaaa catcaataac aatatgtttg gttccattca taatactaca ctttctttga 5700 actctacgct gaatacgttt atgaatgaac tgaattcgtc aatgacaagt gcgtttggag 5760 acacctttct tgcaagtacc gtacaaaatg ttatgaattg cttgctttac agaaaaattg 5820 agaattttga agaaggtttg ttatactagt ctttcaaatt taatctaacc aatagttttg 5880 acttgggttt ataacaaatc ccatattgaa ttacctcttt tacctactga tattttaagc 5940 aaatctatag ataaccaaac tatctattct tctttatatt cttcactaaa ttcatcaaac 6000 agcacagtga gtttctctgg tatctttgat agagttgaaa agtcagtaat aagtgagcta 6060 aatttttctt tcctattttt tttgctttgg ttattgattt gtgcattcgg cttaattggt 6120 gttttatcat cttggctcaa atcattattc cttagccttc tagatttagt tattccaaat 6180 ccaaaggaga acattacttt accagtacaa tcgttagctt ttcctgttac gaagtcgtgt 6240 aggcctcctc ctattcctcc ccgagaatcg cacgtttatg atttccaaaa ttttcaatat 6300 gaagaagatg actgcataga ctataaaagg tccttgggtt taataagcct atctagtgac 6360 cttgctattg acattcccat ctcaccggca attatttcag atatacaatt taactcaatc 6420 acaacagaaa gtgaagagac aacatattta ttgaaagaaa aacaggatag atattagaag 6480 tctacataga ttctaaattt ttcattttgg ataatttaac tgcttaataa atctaatgag 6540 ttggagcgcc tccacgacca ccagccgatg caagcttctc caaagtagct tcatttattt 6600 tgacttcagg aagcttttta ccttctaaag taggttttgg caaaaatcca atagctacca 6660 gatatgacaa atataagccc atctcatgtt ccaaaattgc agctccatta gaaacatcca 6720 cgttagtcca agatgcatca cgtttcaaga tttcacgtgt gtttgtatca tctaattcag 6780 gagcttttgt attagcagga agattatcta acacaaagtg aagtaaggga tacaaagcac 6840 tatcatgaga ctcattaatg acaaagcgct ccaaagcaat acgccaattg acgtattcgg 6900 aaagcttggt attgaagcca aaagtggaaa gagttcctag gaattggttg aaacgaagtc 6960 ggggatgact agttacgtga gcaacaatta ctccttgttc gggatggaaa gcactggcag 7020 ttaccacgcg agcaacgtga tcggcaggaa ccatatttac agtattattg atgttcgggt 7080 acagacccaa ttcaatgcac cctttgacca ttcgaaccaa aaagtcgtcg gtattaatag 7140 caccagactt ggagtcgcct aaaatgtatc caggacgcac aacaacacca cgaaggccac 7200 gtaatcccgc ttgccttact aaatattcag atacccattt gctttgtccg taaccggtat 7260 gcaaatcttt cgaagaacct tgcaaaggat cggattctgg gattccattt cctccctttg 7320 aagtaatttc gttcgaaagg ttaacgtaat actcagtatc aacagttgat gtggatgaaa 7380 caaaactcaa ggatttacct tttcctaaag agcaaagttt taatgcagta attgtaccca 7440 taacattagg acctctgagt ttagaatatg gataaaccca atgtacaagg gcaccattat 7500 gaataacata atcgacgact tcagtaagct tgttccattt cctttcttct ataccccagt 7560 tttcgagagc aagatcacca ttgacaacag aaattttttg ggcccatgat tcatcccata 7620 caccatacgc ggtacaactg tctttaagac gttttagacc atgttcttcc gatgaggcgc 7680 ggactaaggc aatgactttc aagttagagc ttctggtcat aaggtctctt aatataaaga 7740 caccaaggta gccgttagca ccagttaaga aaacggtttt tggctcatca atacccaagt 7800 ctttagaggt tggaaattct ttaggaatta aatctactaa atcaagtgca tctttaccat 7860 attcaatttc aggttctcta gtctcttctt tgcctatatc catcacgcta atcatctcac 7920 ccgatttcat tctttcaatc tctttggcca aaccttcaat agtaggttca ctgaaaacta 7980 aacctaaagg tacattcaca gcaaattttt tgcgaagttc aaaaattaag cgagtagcta 8040 aaatagaatg tcctccaata tcaaagaaac ttgctttttt gttgacatca gtagcgtgtg 8100 gaatgatacg caaccagata tcacgtatat ccctttcagt ggctgtaaga gtttcatcaa 8160 ctccatgttt agaatgtgaa cgagatgcgg cagcaagttg tgatgtgtct gggaaaggca 8220 gagcaggttt atctatcttt ccattaggat tgagaggcat tttatgaagg ggaacaatta 8280 cagaaggaat agcataacta ggaagtttag tcttaagata ttcccgtata tcatgtataa 8340 gcttcctgta cttcttcaaa ccattgacga caatatcttc cgactcagta gcgctatcaa 8400 agtcatcttt atttaaacct tgaggtacaa tgtatgcaac tagcgtgggt tcttcatcct 8460 tatcacgtcg aacaagggta atattttcac ggacattagg atgacgagaa agatgggtat 8520 taatttcacc taactcaatt cggaaaccac gaattttaat ttgatcgtcg gcacgaccgc 8580 tacattctac attaccagtt gggagatagc ggcccaagtc accagaacga tacatacgat 8640 cgcgtattcc gaaccaataa ggtttccagg gcgcattttc tggagttcgg tctacaaact 8700 tggagggatc agcaaaccaa ctctttaaga attttttgct agtcaattca tcatttccaa 8760 ggtagccctc agccaatcca ccagcacgaa gatatatttc accaacttct ccgataccgc 8820 atatcttgtt agtatcaaaa cgattgatca ccaaaagttg gacattcttc atgccacgtc 8880 cggctggaat gacatctttt tgcgattcca aaaatgtttg atcttgagac cgcgcaggta 8940 ctacaaagta cgaaactgaa cgctgagtct ctgtcgttcc atacatgtta acaacgttaa 9000 cgttgttagc aaggacttgt aagcgaagac aatcacgttt cgtcaaaata tcacctacaa 9060 aaaatgcatg gtgtaatgaa ggaattggct catcagcctg agcagctaac agttgaccca 9120 tagctggggt gagatgagtt acagtaacct tatacttgtt agcccattgg gctaattgac 9180 caggggtgcc aatgtcttca gcagtgggta cgattaagga tgcgccaagg aaaagtggtg 9240 tgaaaatatc tctttgaata ggatcatgag caattccact taacatcgta aaccggtctg 9300 attcagataa attaaattcc tgagccatcc aatcaaaata gtaagcaaga ctgaaatgtc 9360 taccttttac acctttagga attccttcac ttccgctagt aaaactaagt gtgggagtac 9420 tatcagggcc tacaacaacg ccagtttgtt cggacttcaa gtgtaaaacg tgttgcaaga 9480 tatcgtcagc tccttttgag actgatcctc ccgttaaaga accatcttta gcaagtttta 9540 aagctggtac ataagttttt agttcaaggc ttttctcaac atactctacg actgtgggag 9600 acaaaacacc tgcatcttcc aaaacaacta aggctctggg cttagcaacg ctcagatata 9660 taatctgacg agcaggtgga tatgctggat cgataactga gaatgtggca ccagctttaa 9720 gtacacccat gaccgcgaca actaaatcca cacctcgata agcataaacc ataactacat 9780 cacccctctc aattccattc tttacgagat ggtgagccag gatgttagaa gactcgtcga 9840 tttgtcgata cgtgtaacta gtgacaggag catcaattgt gaccgaagga gtgactacta 9900 tgcattctct atcagggaat ttagcagcgt tggatgcgaa aatatcttga atggctccac 9960 gataaccact ccaatcaaga tcaacagttg gatctggaag aacattcatt tgggtaggtg 10020 tcattaggtc cagagcaccg ataggacctg taacatcttt ggaagctgaa accactaact 10080 ttaatagctg atcagccaca atattaaccc tactctcaga aaacaacaac tgattataga 10140 ttaatttcaa ttgtaaatcg gggaaagtaa attgggagcg taaagaagtt aattgatcag 10200 aaggtttttt taccgaaacc agaacagtca aatccacatc taatcccgtg gtagaaagaa 10260 agttttcaga aggagcgtct ggagcattgt aaaaacgaag atgaacaaga gttttacgag 10320 ggtcatcttt cttagaaagt ttagcgttca aaaaattaat taaatcagaa aaatctacag 10380 catcagagga gccttccttt tccagatcgc acactttggc taaaaggtca agaaaagaat 10440 cgcttggttg aatgaaagtt ctcaaaacga atggaattgc attctcagaa ctagtaccga 10500 tgctaatgtc ctcatctcca gtcatgcgac taacgaggat tataaaaatc gtcaaaagaa 10560 tattgaaagg agttactaat attcctttag cttgagcagc aacataaacc ttaataagag 10620 ctgtttttgc atcctcagga agtgttcgtt caaacacggc ttcaacgagt ctgctaggca 10680 cgggacgact ataatctgtt ggaagatgag aaattgtttg actcttaagt ctctcagacc 10740 atcgttcaag acgctgattg tactcagtat cacttggagc cgtctggctc attttgaaag 10800 tatgatatgt tgttggtaac ggagagtgtc aaatgttcga actgcctaaa accttcgttg 10860 tagatgataa attgataatc ttcattcaca aacaaaatcc aaaacatatg tttaatatac 10920 tccaataatg aaattgtttt tgttatatca tttcaaatta gtgtttaagt tatttatcgt 10980 acatattttg taaattcaaa tgtactgctt attattgcaa ttattaaact attgtgcaaa 11040 ataataataa taatttaatt ttataataaa catttgtaca aagtgtcata tcacaaagtt 11100 agtcttcaat tttatttctt cgatatttgt atttattatc aacaacccta cgtgtcagta 11160 agcttgatgt gcaaagccag tattgtagat gactcaataa atcaaatgtg gtatagaatt 11220 gtatatactg atacatttca ctttaaattg attattggca acaagcattt ttgctaaaat 11280 gcttagcgtt gagccacatg tttaaatacg ccttctaaaa ccaaaaacac gctagagcag 11340 agtatataca taacatgtcc aaacagctct aatttactat aaaaatttat tgtattatta 11400 taataatact gtaccggtac aatatatgtg tattgttact taattgtgtt tatagtggtg 11460 actgcttttt cttccaaagt ttgttgtgct gtctttctca attactttcc tgaatcagaa 11520 ccacattttt cacaatggca cgtagacctg ctcgctgcta tcgttattgt aagaataagc 11580 cttaccccaa gtctcgttac aaccgtgccg ttcccgattc caagattcgt attttcgact 11640 tgggtcgtaa gcgtgctggt gttgacgagt tccctctttg catccacttg gtctctaacg 11700 aatacgagca aatcacctca gaagctcttg aagctgctcg tatctgtgcc aacaagtact 11760 tggtcaagat tggtggtaag gatagtttcc accttcgtgt ccgtgcacac cccttccatg 11820 ttgttcgtat caacaaaatg ctttcatgtg ccggtgccga tagattgcaa accggtatgc 11880 gtcacgcctt tggtaagccc aatggtttgg tcgcccgtgt aaacatcggt caagttttga 11940 tgtctgtccg taccaaggat tctagccgtg ctactgccat tgaagccctt cgccgttgtc 12000 aatacaagtt ccccggtcaa cagagaatca ttgtctctaa gaaatggggt ttctctcaat 12060 atgctcgtga tgagtacatt gaaaagcgca gccgtggtga aattattccc gacggttgct 12120 acgccaagtt cttgaataag cgtggtagcc tccaagagaa gttggacctc ttccctgaag 12180 cttcattcaa ccttgcttaa aaagtttaat aaaatttttg tgaaactttt cactttgtat 12240 agaactgttc aaacagtttg gtgttggatg aatcggtaaa ttgactgagg tattgcattt 12300 caggaagttg tatttttttg ttgttgattg tttatcatcc ctctatttca agtaagtcga 12360 ttttaaccag cacttgtaga gataatagcc aaataatatc aacttggggg taacaattta 12420 accgactacc aagttgaaat aggcaatttt taaaacgacc agcaactcaa gcatcccatg 12480 tagttaattg tggggcaaat tttagctatt aagactaaat ttttttctca acaaatctat 12540 tacttggcgt taaaactccg catctacttc cacggagtta tttcggccaa aggacgcata 12600 ttcgctgggt taaagtacgc aaaatgactt tttttatgaa aaaattttat ggaattgtca 12660 attttgtctt tttaaatcga gatgaaaagg tgttttatta tgattatccc tgatttcttt 12720 gcttattttc gatccaaaca ctggttttgc tcagtaccat tatttacaac ttttggtgta 12780 cagggatttt aatagaatac agttgtaaag atgcttgcgc taacttaaaa gctacatgat 12840 gggtaataat tgggtgtatt gggtattggg aaaatactgt caacagcatc tggaattcga 12900 ttaatgtaga aaattatagt tacaatgccc gagtagtcgg tgaacaatgg gggccatcag 12960 tcaagatcag tacagcagtt gacgggacag acaccagctg taatgaatag gtcatgttta 13020 ctacgattcc gcggaaataa taataagcta ctgcagagca gtaaaatcta tcacactata 13080 cgtcaaatga aaaataaata attaaatata tatatatata tatatatata tataggtgtg 13140 ttacacaagg taattttatc aagcttttaa tgtagtagca ctagtatgaa tgagctccat 13200 ttcgcttatt tctacaaaag ggacattaga tagtaagttt attgagatgc gaaaaaactc 13260 gtgcatcgca tgcattcacc acggagatgc atagaattgc aatttttcta tctaacagat 13320 aaccaaatca aattgtttag tcttatcatt tgaatctgtt tggaggcttt gcaaatgtat 13380 aaaagtcagg cacacgaccc ctaaagtcat tttagcaaga tgggacttgg tattgtattt 13440 ttgcaaagtt caatgaccat gaacctcgtt atttggagtg gataagcatc ttagaggaag 13500 ggtgataaaa cgaggagcat gatcgaaaag atggtttgag gaacaagagt gaggataatc 13560 caagtgcctt attgaaaacc gagcgttgag taaatataac gaaaagatgg ggggagtagc 13620 atgctttgct ttcttttgct gttttctcta atagattgac caacaatcag ctttggcccc 13680 cttattcaag ttttggctat cgcgccgcgg cagcacaacc gagtttcgtg gcaaacagta 13740 ggcatttgaa tcaaatattc atataaatat ccttggttta tttataccct gtctaaatgc 13800 aagcaacact attgcttgct gaaggaaaag ggtttgaaag gcaaaaaaaa aactaataag 13860 gattaaggtc agccattcaa tcgataatcg agtatagtcg accatcgaaa acgtttcatt 13920 aacaatcgaa tattccatca gcagttagca tttcattaat ggcttggaca tttctttaac 13980 aatcgagcat ttcaccaagg gtcaagcata cttgatattc aaacaagtca atttcgaaag 14040 tgcctattcc atattgaatt tgtttgaaaa aaaaataaaa taaaaaaagg aagaaaaaaa 14100 aattttctta attctatcca cttggaaatc aaacgtttgc ctcaactctt tctaccttgc 14160 ccagcctatc taacagcagt atgccatatc gactatacta cgaattatgt aaacccatct 14220 agttattggg atggaaatcc gcctctcaaa aaaaaaaaaa aggattgatt ttcaattaaa 14280 taacctacat ttaccaacgt tgattaccta atgacgattg aaaaaaaaaa taaataaata 14340 aagaaaaaaa aaattgcaag cagccggatt tgtcctgata ataataatca acagactcct 14400 caatcagttg tggattgtta gataaaatgt tttatctttt atctcccatt ctttcattta 14460 ttttatctgc tttttatttt tttaattttc tttgtttgtt tcttttttgc agtctcgatg 14520 aaggagaaga acgtctgtaa aaatatcaaa catcgtcgaa aaaaattcta tcaagtggat 14580 aagcgatcgt tcacctgcaa attcttatct ctccccttct tgctgttgca ttgcagtaaa 14640 ctggtaaaag cgagatatcg gtttttccgt gcagcgctga aacctgcgta aagctctaga 14700 atgaaaaaga aaaaagaaag gatcgaaaga ggaaccaaaa tgtcttatgt tccaagtgtg 14760 tgctggtaag ttgggtaaat tcaccaacag taacttgtgc atctctttgt tgccagtgaa 14820 ctttcgcatc taatttgcag ttcatcaatt gagccttaat aagttgtcat tatagagaga 14880 gagagagagg taggaaaaaa aaaagcacat acacacacac aaagcttcat aattacaatt 14940 ccgtttgatg gcttatttca ttgatgcttt gtgtttgttt gctttttttc ttcttacgtt 15000 gaacatttac attatgctat aagtttgtct ttcgaacgtc aatttacaca tggaatggaa 15060 acgtgttttc tactaagcat gtgctttgga agagtgtgtc tcggcttacc cttcttctcc 15120 aggttaattg actgatagta actccggaac gagcggttac tcacttcttg ctccttgttt 15180 ttccgtccta ccctatctct tctctcctag acctctttcc taacggttta ttctcgctta 15240 tcagtttaaa cttgtgccta tacgcacaag gagttgatta tgtttccacg tccaattgtt 15300 atccgtctct ttccgcttcc ttatctgctg caaaactttg gttgcccctg cctcgtaatt 15360 cgattttctg actgtggcta atagctttat gccctcttgt tcatggacgg tggaatggat 15420 gatgacagct tgttacatgc atgtcttctt cttacttatg tttgcaatta aatagatatc 15480 gctcttgtgc ttgcctaatt atgagttcat tatgttcact tgtgcttgta cttaaaattt 15540 catttacgca ttccttgatc tcattcataa agcgttctag ggagcttcac atccgtgcta 15600 gataggatga tctttatttt aatagacgat cggaagtcat tggcttggtt gctagtagat 15660 tgcactcttc caaatagggt aactaagata agacgattat tatttggttt tcgattcttg 15720 ttagctcaat gagtatggga aaatacaact ttcatctcat gtggtcaaca ctgcaattgt 15780 tcgacacaag taattttttt ttggtgctat gtgtttgtca attttgggtc ggggcccagt 15840 cgcgctactc cacttttgat gaaatttgtg aacttttttt ttgcaaccct tttcttgctc 15900 tccaagtgcc agtttcttct ttgctactta ctgcttatct ataaagtatt gttaactaag 15960 ttatcgacac ttaagttttt ggcaaatttc ctctacccgt tacttgatat taccttacgt 16020 caaccgccaa cgatttttcc ttatccatat tgtgcggcta attttcgcat aaaatagggc 16080 ccattcccat tcaattttaa tcttttcttc agacaatcgg ttcgaattgt tttcaaaaga 16140 gcaaaaggtt cgcttcctta gtgattttcc tcccttttat taaaaaaaac ttatacatct 16200 tgcgcttcag gcattgaagt aagaattgtt tgtttgtatt ttgcaattga ttcttctttt 16260 ttttttcgtt tcttctttcg aatcgtgtcc tgttccatct ttagttgctc tttatatttt 16320 tgaaatatac tttctttttt tttacatact ctgtaaaaaa aaaaaaagaa taccttgaaa 16380 aaagggaaac tcccaaactt tttgtattta ttaaaaagct gtattagaaa tagtcatagc 16440 gattttctcc attgccttat tcatacatac acgcgctcaa acatatctgg ctcttaggca 16500 attgaaacca gtttccgaat ttattataga tatttctcaa aaacttttag ctaagcgaaa 16560 tttttttgaa atatatattt tattctaaat tctgcatttt tctaaatctc ttcttgtttt 16620 ttattgcaga cgcatattat acacatatct tttgttgttt tttcgcatct tgcattattt 16680 cacccatccc tttattacgt ttttaatttc ttatccgtcc tcttattttc gctatcagtg 16740 ttgctaatcc caactcattt attaagacat tcgctattta aatacgcact atacgcagcg 16800 agtgtttccc aatcgtttag taacttcttc atctagttgt tgctgagctt tgtcttttaa 16860 aaaagtggtt ctgttactta aaaaaaaggt ggttttctga aaagcttttc tttttctttt 16920 tctttttctt cttttttttt ttaaaaacct gatctcaatc agtcggtcat tttgttttct 16980 ctttaatcat acatctttac tcctctatcc caatatcgtc ttactatttc tctctacctt 17040 ttcaataact ttctctgtct aaagtatgtc gtcgccagat cgctctattg acattgacct 17100 tgaaaaatat ccttcaacgg ctaccaagtc cgtctacggc caatcgaagg atgataaaaa 17160 tgttttcgac attcatccca ccgaatccga agtcatcccc ggtgaagtcg agtatgctga 17220 tactccttcc catcaaaatt tcttgcaaaa gttttttagc gacttcaaac ccgttaaagc 17280 cgaccgcgag gatggtgtcg cattaaagcg tcatctgaaa ggtaggcata tgcaaatgat 17340 tgccattggt ggtgctattg gtactggttt gtttgtgggt tctggtagtt cacttgctga 17400 tggtggaccg gcttctgtta ttatcgatta tactttgatt ggtattatga tgttctttac 17460 tgtctatgct ttaggtgaac ttgctgtttc ttatcctgtc gctggtggtt tctataatta 17520 cgcagttcgt tttatcgatc cagcctgggg ctttgccgtt ggttggaact atttcatgaa 17580 ttatttcgtt acatttccac tggagttaac tacttgtgcc atcactttcc gctactggac 17640 agacattaat agttgtgctt ggattacgat tttcttggta tttgttatat gtatcaatct 17700 tttcggtgtt agaggttatg gtgaagttga atttattcta tctacgctca aagttgttgc 17760 cactactggt tttattattt tggctattat tattaattgc ggtggtgttc ctactgatcc 17820 tcgtggctac atcggtggta aaattattaa aaacaaacct ttccgtcata gctttaaagg 17880 tttttgttcc gtgtttacta ctgccggttt ctccttctca ggtactgaag ttgttggttt 17940 agctgctgct gaagctgaag atcctcaaaa gtctctccct cgtgctacca aacaggtctt 18000 ttggcgtatt gctattttct acgtcgtatc tttaatttta attggtctgc ttgtttcacc 18060 agatgatcct cgtttgatgg gtaatagcag cgatggtagt acctctccct tcgtgttggc 18120 cattaaagaa gcaaacatca gaggccttcc ttccgttttc aatgcagtaa ttatcatttc 18180 taccgtctct gttgcaaatt cttgtacttt cactgctagt cgtactcttc atgctatggc 18240 cgctaaaggt gacgcacctc gcttctttgc atatactgat cgtcttggtc gtcccctcct 18300 cgctatggct gtttgtttgt tgtttggatt ttttgcatat atcaatgccg ccggtgatgt 18360 tagtgacact gttttcgatt ggttattggc tatttccggt atctcaaact tcttctcatg 18420 gggcagtatt aatctttgcc atatcgtctt ccgtcttgct atgaagaaac aaggccgttc 18480 tttggatcaa cttggatttg tatcacctat gggtatttgg ggttctgcta ttggattggc 18540 tttcaacatt ttgtgtctta tggccgaatt ctatgtatct ttgttcccca tcggttcaaa 18600 gccaaatgct aacgattttt tccaaggata tcttgctgct ccaattgtga ttgctttctt 18660 tattggctac aaaatttatg atagaagtca tattccctca ttgagtaaac ttgatttaga 18720 cacgggactt cgtacctatc ctccaaaaga taaagaatct gagaaaattc gtgatgcgaa 18780 gggtttcttt aagtggattt ggcaatctct ttgctaaatt ttattttgca ttatcaattg 18840 atttccaatc aacttattta aaaaaaaaaa agaaaaaaat ttgcacacta tttacttttt 18900 gatgtcttta ggattcgaaa ttttttttta ttttggtttt gacagtgaag aggtcgcctt 18960 taatttagtt taaattactg cactattact tgtacactaa gtgtgagaaa gtatgatgtt 19020 tatcaaaatt tttcaagtac atattttgat tgatttctta atttattact ttggttaata 19080 atatgtgtct aacgttgtaa gtttatatgt tgaagcatta gtgtttaatt attttgtagt 19140 ttttatggtt tctttgtacg tacatttatt aattcgtgtt tgtacttttt attattacgc 19200 ctccgttgtt gtttggtggt tttggtatta tgccttgcat tcgcataaat taaataaaaa 19260 tcgtgtctac ttggtgtttg gactgtttgg aaaatcgtac ctagaaaata taatgttgag 19320 ctccttggtt agcttaatcg caagctgtat aattctttct attaaagatt ttattccata 19380 ataacacgac caatccgtct tcgtaactag atcgcactca ctgtagtacc attaaaaaga 19440 ccgccttatc aagctcaaag tattaacaaa aataaaacta taggctaaat atacgcagtg 19500 tttaaaatat aacattctac ttagagcata tagtcgctgg tagatctgaa cggccacact 19560 ctaaatattc ttaatcatcg cgcaatttta aatttcactt catacctatg ataaaccttg 19620 tttagttgaa actataaaca ctcaattaat ttccttttca acgtcgttaa ttaaaaattt 19680 gattaatgat ctgtgcaaaa aaagtgtcac aaaccgggat cgaaccgatg accaacagat 19740 cttcagtctg tcatgctccc aactacacca ttgcgacttc attgaaaatt cattcatact 19800 tgcaatatat acacaaataa catatatagt agcaaatgaa aaggaattta gtaaatattt 19860 tcattaatta taaggaattc gtaaaaaaag aagctgaatt tattcaccat gctttaaact 19920 tatctgcgtg tattgtagga ccgaactgcc aaaactgtag aaatatattt tttagagcaa 19980 atgtgaataa aatgataacg tatacgctat cgtacgcttg ttggtaaaca ctgcactgat 20040 atgaaatttg ataagtattt aaataaaata gcaaatttta cacatggtgt tgtaaatgct 20100 ttacaaattt cagtctatct gcttgggtta tcagtaagaa tatcatgtgt aattacagaa 20160 aataaaaact attgataaca aaaaaaaaaa ccttattatt taaatttaca aataaacgtt 20220 agcttcgcta cgcatagtta gtaaacaaat tttatatgcc tcaattgcct attagtgctg 20280 aagaaaagcg ttaacactat aagctaactt tataatttcc cagtttcaac tatcagtgta 20340 tcgaatgaat gattatctac agatgttcta tttcaacaca cttagttcaa ttggcaattg 20400 cgtttcacct aacataatca atattagctt catctatgat gttggttaca ttcagcaatt 20460 cttttatgga tttattgcct tgttcttgag tactcgaata taaaatcccg caaaaccata 20520 aaatgtgttt aagaaatttc aagtagattt aatacgaatt taacatttta ctctcgagca 20580 ttgtaaaatc attgctgagt taatttttag tggagcttgt aaatgaggtg aagaagttac 20640 tcccttgaag tttgccaaaa aaaataatga taatgataat aattaacaca tagaaccaag 20700 ctcgcgagga ctcaatccgt ggacgtatca actaaagctt tcaatttttt tagtacaaaa 20760 atattgactg caatattttt acaccatcac agtcttgatt tagcaaaaag ttgcttttga 20820 actagaatgt tggctaaata aatgtgttgc ctgattgtac atgatatatt atcagctttg 20880 tcaagggaaa aaccgagacc gaagaaagtt aaaactgaga gaaattctag atatgctact 20940 ataagtgctc tttgtcatga gagaaacatg attctacgtg tctgattcac gcaaaggatg 21000 catcaatata ccttctttta attacaggat gatgcatttt taatttgtta ttgttgtgaa 21060 ttctatgtca actgtttgct aatataggcg gcgcagagat atgaaaacca aaccgtgaca 21120 atacacctaa gctaaaaggt caacgcacgc ctaaactagc agctcaactc atgattggac 21180 taataattta aaactaaaac taaaacctaa acctatttta caaataaaac tcataattag 21240 gctaacaacc ctacccatca actaacgact tgacggtatg ctattccttc ttttttttaa 21300 agcttcacta ccatcgaaat atatataaca gtagtaaaat tgtaaacttt tatttttata 21360 ccatagtagt atggctatga ttggaaggtt gtagtgtcag tcaagttgga aaaactgttg 21420 gcactttttt tctgaatcaa tggaattctt atcaaacaca tgcaaacgta taaagaagac 21480 ttgaatagat aatctttgaa ttcaaacaaa tcctagtcaa ctgaacaacg catctacctc 21540 agcagtcctt gggaaatgta taaataggca agcattaaac ttttatatat aaaaccatca 21600 agatctctat ttttaactcg gtggtttctt tcacaagact tacttcaaga acgacaacac 21660 atcctgacag ttaattcatt aatactaata ctatcgagga ttctgtcatc caagtggaat 21720 gaacatgggc atcaaaggaa tgtttcctca aagtgagaac tatagtgttg caagagcgaa 21780 tacttggtcg cttagaacaa aacgaattac tgtcattagg atatgctcaa aagtgtggcg 21840 ctatatcttg tatctattgc tacgttcatt cattgatcca acagtatggg tatagaaaga 21900 agacgataag caggagttgc gcaaacgaag ttatggagtt tcttgcatgc atgcatgttt 21960 tggcataaag ctggtacttc gaaatatgcc tatgaaatct ctacctgctt tgcaccctaa 22020 atataacgtg tcgtcttgta gctgcatgtg aattacaacg attgatagat gaaaaacaaa 22080 tcgacttgtt gcccatttca tcgtttcaaa cgactggtag tgttgcttgt gtccataccc 22140 atgctgtgtc catatccata ctatgtccgt gtgttttgct ttattacact tggtcaaaga 22200 aatctatatg atgttcttta cgaaacccac aaagtcacaa ttgtgatctt ccaatgctta 22260 ataaatacga aatcttattt cgatttacag gctgggcatt cacgaaacat agcgttttta 22320 catttctaca ggcacactat aaacaacttg caatatctgc catcacttta tttctccaac 22380 tttgttcaag ttaaaagtgg cagaaagtgt ttcccgatat gagataaccc aacgcatatg 22440 ttgttgcaaa aactaaacgc ccattcatca aacgagtcga gatgagagga atcattgtat 22500 aaaaggctag catgtaaaag ctggaagaag gaaagaacac gggatatgta atggaacatg 22560 ggaaattgat atggacattg atatggacct tgatatggac attgatatga acatgaatat 22620 ggtatagaga actacatcga cacagaaaag aaaacaaaag ttgctaaaat gacaaaggtg 22680 ccgaatcaac aggccatagt accgatggaa tccaaataca atccaagaat cattcaaaca 22740 tcgcaaacat ctttgctcga cattgttgtt ttgaacaact actaagagtt gcaaatgtga 22800 aagcaacaac attcaacgta tctacaaatt tctcgctgtt ttgcatatac atttctattt 22860 aatagtgaat tagcgtataa gaaagaaatg gagctttttt ggattacaag tgataagagt 22920 aggtgtagga gtaggactca tttattgaat ctggtgattt gcgtcggaag gttgagaata 22980 taaagagcgt gtgaaactaa gccatgtaat ctaaaacttt accgaaactt tcagatc 23037 //