ID SPAP17E12 standard; DNA; FUN; 19082 BP. XX AC AL691405; XX SV AL691405.1 XX DT 13-MAR-2002 (Rel. 71, Created) DT 13-MAR-2002 (Rel. 71, Last updated, Version 2) XX DE S.pombe chromosome I BAC pB17E12. XX KW 6-phosphofructo-2-kinase; csn2; cytochrome c oxidase assembly; KW fructose-2,6-bisphosphatase; mitochondrial carrier protein; PCI domain; KW peroxisomal biogenesis; putative Oligosaccharyltransferase gamma subunit; KW putative SAM-dependent methyltransferase; ribosomal protein L18; KW ribosomal protein L37; rpl18-2; rpl37; signalosome subunit 2; SMN protein. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-19082 RA O'Neil S., Harris D., Wood V., Rajandream M.A., Barrell B.G.; RT ; RL Submitted (12-APR-2001) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk XX DR GOA; Q8TFH0; Q8TFH0. DR GOA; Q8TFH1; Q8TFH1. DR GOA; Q8TFH2; Q8TFH2. DR GOA; Q8TFH3; Q8TFH3. DR GOA; Q8TFH4; Q8TFH4. DR GOA; Q8TFH7; Q8TFH7. DR GOA; Q9HFR0; Q9HFR0. DR REMTREMBL; CAD27499; CAD27499. DR SPTREMBL; Q8TFH0; Q8TFH0. DR SPTREMBL; Q8TFH1; Q8TFH1. DR SPTREMBL; Q8TFH2; Q8TFH2. DR SPTREMBL; Q8TFH3; Q8TFH3. DR SPTREMBL; Q8TFH4; Q8TFH4. DR SPTREMBL; Q8TFH5; Q8TFH5. DR SPTREMBL; Q8TFH6; Q8TFH6. DR SPTREMBL; Q8TFH7; Q8TFH7. DR SPTREMBL; Q8TFH8; Q8TFH8. DR SPTREMBL; Q8TFH9; Q8TFH9. DR SPTREMBL; Q9P347; Q9P347. DR SWISS-PROT; P59289; R37A_SCHPO. DR SWISS-PROT; Q9HFR0; CSN2_SCHPO. XX CC Notes: CC This identifier should be SPAPB17E12, because the clone was a bac. CC However, this identifier is too long for EMBL, CC so it has been submitted with identifier SPAP17E12, CC which omits the *B* CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC BAC pB17E12 is overlapped at the 5' end by cosmid c1420, CC EMBL entry SPAC1420, accession number AL121732, and at the CC 3' end by cosmid c1565, EMBL entry SPAC1565, accession number AL390274. XX FH Key Location/Qualifiers FH FT source 1..19082 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="BAC pB17E12" FT /map="IL" FT misc_feature 1..110 FT /note="nominal overlap with SPAC1420 S. pombe chromosome 1" FT CDS complement(<1..283) FT /db_xref="SPTREMBL:Q8TFH9" FT /note="182 (-2) 1 36 TR:Q9UTM2 Q9UTM2 PUTATIVE CYTOCHROME C FT OXIDASE ASSEMBLY PROTEIN (FRAGMENT). [0]" FT /gene="cox11" FT /gene="SPAPB17E12.01c" FT /gene="SPAC1420.04c" FT /product="putative cytochrome c oxidase assembly protein; FT putative requirement for heme A synthesis" FT /protein_id="CAD27494.1" FT /translation="MPILTCRYKILFLYNLRNCFTFQNQRCLIPYGTTTTIRWYNANFQ FT AVQNNFSDYKNELISSHRPEASSLLDFLVKDQKKSGDISLHTKFNLYVD" FT CDS join(867..1033,1139..1487,1562..1753) FT /db_xref="SPTREMBL:Q9P347" FT /gene="yip1-b" FT /gene="SPAPB17E12.02" FT /product="structural similarity with SMN protein; yip1p; FT putative smn1/yab8 interacting protein; based on 2 hybrid FT data and similar to human SIP1; possibly involved in FT spliceosomal snRNP biogenesis; no apparent S. cerevisiae FT ortholog" FT /protein_id="CAD27495.1" FT /translation="MPSKRKRNPLQYQTSGSLDEETNQRSAFPQIDNNSASESLEYDIP FT LDGLDYLATVREEARKLVPFVAARREPETRETIPLRKLEIEAGKKSFDPFLRYLLNIID FT KEGERLEQYMESSSLDASILPKNLQQWRVYIEHKAPCWAILAVVDLATVLEILESLSSW FT LEKDAIDLQSQWIFCFCYKLPELLNGEDISTLRSVLKSLRSTHTSFPALQMSASALQAV FT LVYRYGQKDLFQT" FT misc_feature 1034..1039 FT /note="gtacga, splice donor sequence" FT misc_feature 1126..1138 FT /note="ctgacaagttcag, splice branch and acceptor" FT misc_feature 1488..1493 FT /note="gttggt, splice donor sequence" FT misc_feature 1547..1561 FT /note="ctaacatttttctag, splice branch and acceptor" FT CDS join(2006..2089,2132..2503,2600..3079) FT /db_xref="SPTREMBL:Q8TFH8" FT /note="pB17E12.cand.2 score = 15.17" FT /gene="SPAPB17E12.03" FT /product="putative peroxisomal biogenesis protein; similar FT to S. cerevisiae PEX12" FT /protein_id="CAD27496.1" FT /translation="MDSPSLLEVLQVQQVEKLISPSLRFILAYFTHRYPRFLLRAYNSF FT DGIYLLVKLLLEKSQLKKWNATSVERRFQLKRVIAVRDSSIIAEEFPQESESATSLNGI FT DVLKKLFLTYCIPYLLEKCESLTTVKENHTAVSILSLQARDKQKGALSWLYYLLYALGK FT TPYTNLADHILRQRVIYNVENIHSRKLISTREKSSLLTSIADHSMEGFLIIIQLIDWWQ FT SNNYESHLKKGEVAFTELAPPKLPFEINVSTTDICKICGEKIKNPAVLSTGFVFCYPCI FT QVWLQRHPFKCPVTNLELSRKGESFWRLMI" FT misc_feature 2090..2095 FT /note="gtaagt, splice donor sequence" FT misc_feature 2118..2131 FT /note="ttaatctctttcag, splice branch and acceptor" FT misc_feature 2504..2509 FT /note="gtattt, splice donor sequence" FT misc_feature 2583..2599 FT /note="ctaatacctacttacag, splice branch and acceptor" FT CDS join(complement(4607..4629),complement(4470..4564), FT complement(4348..4429),complement(4248..4308), FT complement(3142..4194)) FT /db_xref="GOA:Q9HFR0" FT /db_xref="SWISS-PROT:Q9HFR0" FT /note="pB17E12.C.cand.5 score = 25.59" FT /gene="csn2" FT /gene="SPAPB17E12.04c" FT /product="COP9/signalosome complex subunit 2; contains PCI FT domain; no apparent S. cerevisiae ortholog" FT /protein_id="CAD27497.1" FT /translation="MSNDFMLEDDENYDFEFEDDDDDMIEPYVDVENCYYNSKSLKEEN FT PESALTSFYSIVEKCEGEQNEWAFKALKQITKINFQLKKYDDMLQSYQRLLGYTNWLSI FT TKNYSEKSIYNIVEYASSCENTEFLEKFYDVTTKALQNLNNERLMLKVLMHVARFLLTQ FT KNYHKFKYLLRQMHELLSDENNSVADQNRGTHLLELYSLEIQMYSDIEDNKRLKELYQS FT SLRVKTAIPHPRIMGIIRECGGKMHMQENQWSEAQTNFFESFKSYDEAGSSDRIRVLKY FT LVLANMLSESEINPFDSPETQPYKDNPHIIAMTKLVEAYQIRDITAVERILQTYQHDIL FT DDDFIRQYVDKILYSIRSQVLIELVKPYTSVKLSLLAKKLGVSISIIEQALVGLIIDER FT VNGKIDMVNEVFTISQPKNTIHNQLVEDVQKLWNTATK" FT misc_feature complement(3184..3390) FT /note="Match to PCI Score 45.78" FT misc_feature complement(4195..4213) FT /note="ctaattattgggttttaag, splice branch and acceptor" FT misc_feature complement(4242..4247) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(4309..4321) FT /note="ctaactcttatag, splice branch and acceptor" FT misc_feature complement(4342..4347) FT /note="gtatga, splice donor sequence" FT misc_feature complement(4430..4444) FT /note="ctaatcgattttaag, splice branch and acceptor" FT misc_feature complement(4464..4469) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(4565..4578) FT /note="ttaataataaacag, splice branch and acceptor" FT misc_feature complement(4601..4606) FT /note="gtaagg, splice donor sequence" FT CDS join(5652..5886,5954..5988) FT /db_xref="SWISS-PROT:P59289" FT /gene="rpl37" FT /gene="SPAPB17E12.05" FT /product="60S ribosomal protein L37" FT /protein_id="CAD27498.1" FT /translation="MTKGTQSFGMRHNKSHTICRRCGKRSFHIQKSTCACCGYPAAKTR FT SYNWGAKAKRRRTTGTGRMSYLKKVHRSFKNGFRAGKPTSAATA" FT misc_feature 5655..5816 FT /note="Match to Ribosomal_L37e Score 152.71" FT misc_feature 5887..5892 FT /note="gtaagt, splice donor sequence" FT intron 5887..5953 FT /note="confirmed intron" FT misc_feature 5938..5953 FT /note="ttaacattttatttag, splice branch and acceptor" FT CDS join(6790..6967,7054..7138,7140..7225,7286..7387, FT 7430..7536,7575..7868) FT /db_xref="PSEUDO:CAD27499.1" FT /db_xref="REMTREMBL:CAD27499" FT /note="pseudo or frameshifted" FT /pseudo FT /gene="SPAPB17E12.06" FT misc_feature 6968..6973 FT /note="gtgaat, splice donor sequence" FT misc_feature 7038..7053 FT /note="ctaattactcgattag, splice branch and acceptor" FT misc_feature 7226..7231 FT /note="gtataa, splice donor sequence" FT misc_feature 7270..7285 FT /note="ctaatgagacttaaag, splice branch and acceptor" FT misc_feature 7388..7393 FT /note="gtatgt, splice donor sequence" FT misc_feature 7416..7429 FT /note="ttgacatctttaag, splice branch and acceptor" FT misc_feature 7537..7542 FT /note="gtaata, splice donor sequence" FT misc_feature 7563..7574 FT /note="ctaaacttctag, splice branch and acceptor" FT CDS join(complement(8257..9091),complement(7902..8209)) FT /db_xref="GOA:Q8TFH7" FT /db_xref="SPTREMBL:Q8TFH7" FT /note="pB17E12.C.cand.4 score = 18.48" FT /gene="SPAPB17E12.07c" FT /product="putative tRNA splicing endonuclease subunit" FT /protein_id="CAD27500.1" FT /translation="MSKNHEVYKDALPISLAYPLPPIILTNPLTWIPYIYRYLFRKTPR FT QVQWQCQLHESDLSCVVTDSEAIKKFWTSGFFGKGNLSRSEPTWHTRTKRSLGLLGFDE FT DLVAEEVTARRRFQRKQFKAQRAYRENRARERQLLLENGKPIPASLEEDAELPEYLTKS FT LKDFSRVSENPYHITSVPNVEHLQLTFPEAFFLASLGVLRINYENPNFELLPILKLFAN FT IVANSVALTHDYSLQQSHEDPIIEPDNKFLTELAAYFYFRQQGWVVKNGTKFSVDFLLY FT KKGPVFSHAEFAILLIPCVGNKQKYNMQWHEVHCLNRVIAQVKKSLILCYVQCPSIEDF FT NKIWKNQASMNEWDWAESVLRQYLIRCVTLRRWVPSRNRD" FT misc_feature complement(8210..8223) FT /note="ttaacaagaaatag, splice branch and acceptor" FT intron complement(8210..8256) FT /note="Intron predicted by HMM_intron, Score=19.44" FT misc_feature complement(8251..8256) FT /note="gtaagt, splice donor sequence" FT intron complement(9127..9309) FT /note="Intron predicted by HMM_intron, Score=13.18" FT CDS join(9968..9990,10070..10442) FT /db_xref="SPTREMBL:Q8TFH6" FT /gene="SPAPB17E12.08" FT /product="hypothetical protein; sequence orphan" FT /protein_id="CAD27501.1" FT /translation="MVFYLNGELIHYSIGPTIIRLFSLNVINFSFLSLSVSFITHGDNA FT YLLPAWIAISCFQTAAYIVQDWITSPIIRTLPFRSSSSSSSNYRHNLDFLEITVFAVVP FT VGIASFFTMVMLIWQLYKYPDSFLVSA" FT misc_feature 9991..9996 FT /note="gtaagc, splice donor sequence" FT misc_feature 10051..10069 FT /note="ctaactatatttgtactag, splice branch and acceptor" FT CDS join(10818..11177,11224..11475) FT /db_xref="SPTREMBL:Q8TFH5" FT /note="pB17E12.cand.5 score = 14.72" FT /gene="SPAPB17E12.09" FT /product="hypothetical protein; sequence orphan" FT /protein_id="CAD27502.1" FT /translation="MQDRFLKENTEIINLSSSIHPNRDSYLDSQSDPLNQNLYNIETEN FT VKDLNIEDVDYYEKLQNFKIVDENIDPGLRTYSKRSVGVNNTFQNPCNRKIEGYIKEIE FT RLSNSNKNLQAAVLQMAVSDTDDPRLKEEYKQTEKELLREISGNHKSKILKLEEELNDL FT KHSMKEMQLYMTKIIDKAMNNASLENLFSLDENNTKIHDK" FT misc_feature 11178..11183 FT /note="gtatga, splice donor sequence" FT misc_feature 11207..11223 FT /note="ctgactgctctcattag, splice branch and acceptor" FT CDS join(complement(12458..12652),complement(12234..12284), FT complement(11531..12190)) FT /db_xref="GOA:Q8TFH4" FT /db_xref="SPTREMBL:Q8TFH4" FT /note="pB17E12.C.cand.3 score = 17.36" FT /gene="SPAPB17E12.10c" FT /product="putative SAM-dependent methyltransferase; FT putative rRNA large subunit methyltransferase; similar to FT S. cerevisiae YGL136C" FT /protein_id="CAD27503.1" FT /translation="MSMRIWSRSSSAYSAIARSSSWFNNSLFSSCLLRFYSNPPKKTKK FT NTLISLRKSAETANEKFIEKINKEHQLFKPGQIVVDLGCAPGIWSTIAARHVGLFGRVI FT ACDIIPCRLPENSSMIQGNILSMEIQLEIAKAAIRSRNSFFRNQQDHNSASIPYLQSVF FT EEERDTKEKAKIEDLSADVIMSDLGPPFPMVQGFEFWISKLPYLAMQTNEHLAVKDELD FT SLYLAQAALLFAIKALKPDGIFLCKVLESSHLRSFAEDLSMCFKCVKKIQFKTKIKDEL FT YAVYFCSGKQLSCHSKLLNI" FT misc_feature complement(12191..12203) FT /note="ctaatcaatttag, splice branch and acceptor" FT misc_feature complement(12228..12233) FT /note="gtaggt, splice donor sequence" FT misc_feature complement(12285..12296) FT /note="ctaactattaag, splice branch and acceptor" FT misc_feature complement(12452..12457) FT /note="gtaagt, splice donor sequence" FT CDS join(13247..13452,13504..13621,13680..13759,13876..14222, FT 14269..14447) FT /db_xref="GOA:Q8TFH3" FT /db_xref="SPTREMBL:Q8TFH3" FT /note="pB17E12.cand.6 score = 18.62" FT /gene="SPAPB17E12.11" FT /product="putative Oligosaccharyltransferase gamma subunit; FT member of a complex of 8 ER proteins that transfers core FT oligosaccharide from dolichol carrier to Asn-X-Ser/Thr FT motif; similar to S. cerevisiae OST3 and multiple alignment FT with human n33; OST family" FT /protein_id="CAD27504.1" FT /translation="MNFFKILSFFSLFVITCFAKLDLNSKTDADGVIQITGRLFHRIVN FT GKQDFTTVALFSADSSTMNCDVCRLIEPEFKALANSYKLKYGLDSGIRFTYADFGKNKN FT LFQDFSIESVPNFWIFKPKSIQAIHVDLSHGVTASHLAAIVEKHTGKIADIVYKQDQAK FT RVGAFLSYIIVGAALFFTRKIIVKIFTSRKVWAALTIITVITLSSGYMFTRIRFSPYSQ FT RGEHGENLWLAGSQQFQFGAEVQVVSLLYTALTMSSIFLAIVAPKVEGAKRQTLFVIIW FT LAFLWIGYSFLVDIFKRKVSMYPFKLLI" FT misc_feature 13453..13458 FT /note="gtaagc, splice donor sequence" FT misc_feature 13491..13503 FT /note="ctaacgttgttag, splice branch and acceptor" FT misc_feature 13622..13627 FT /note="gtatgt, splice donor sequence" FT misc_feature 13664..13679 FT /note="ctaattgtactcatag, splice branch and acceptor" FT misc_feature 13760..13765 FT /note="gtaagt, splice donor sequence" FT misc_feature 13863..13875 FT /note="ctaacttacttag, splice branch and acceptor" FT misc_feature 14223..14228 FT /note="gtaagt, splice donor sequence" FT misc_feature 14256..14268 FT /note="ctaacatttttag, splice branch and acceptor" FT CDS complement(14648..15601) FT /db_xref="GOA:Q8TFH2" FT /db_xref="SPTREMBL:Q8TFH2" FT /note="pB17E12.C.cand.2 score = 11.19" FT /gene="SPAPB17E12.12c" FT /product="mitochondrial carrier protein" FT /protein_id="CAD27505.1" FT /translation="MQKDKFGPCAPSRIPLLSNDLISMLSGGVAATVSRTAVSPLERMK FT IIFQVQNNKEYTSLTSTLVKIWNREGLIGFFRGNGTNCLRAFPYGAVQFATFNMLKQRA FT LKNRSHQNLENHERLLFGAIAGAASCATTYPLDIARTRLSIETAGLTSRSLAINNVANN FT SLKVKPLTLWSTLLYIVQHEGGYPALYNGLPATLLNVVPYVSICFFTFEFCKQKFFSNA FT DLTAFQKLFLGGFTGIIGQTLTFPADVLRRRFQVNRIPGIGHNYKNIKSAIFHIYKTEG FT INGFFRGYSSNMLKIIPVMSITWYTYETVSKMLHDL" FT misc_feature complement(14654..14929) FT /note="Match to mito_carr Score 92.03" FT misc_feature complement(14933..15253) FT /note="Match to mito_carr Score 81.05" FT misc_feature complement(15281..15541) FT /note="Match to mito_carr Score 100.35" FT CDS join(15744..15746,15818..16378) FT /db_xref="GOA:Q8TFH1" FT /db_xref="SPTREMBL:Q8TFH1" FT /note="pB17E12.cand.7 score = 21.37" FT /gene="rpl18-2" FT /gene="SPAPB17E12.13" FT /product="60S ribosomal protein L18" FT /protein_id="CAD27506.1" FT /translation="MGIDIERHHVRKSQRSKPASENVYLKLLVKLYRFLARRTDSRFNK FT AILKRLFQSKTNRPPISISKIAALTSRKSASLEGKTTVIVGTVTDDERLLTVPKLSVAA FT LRFTKSARARILKAGGEVLTLDQLALRAPTGSNTVLLRGKKHAREAYRHFGFGPHKHKA FT PYVRSEGRKFERARGRRKSRAFKV" FT misc_feature 15747..15752 FT /note="gtaagt, splice donor sequence" FT misc_feature 15802..15817 FT /note="ctaataaatttattag, splice branch and acceptor" FT misc_feature 15845..16375 FT /note="Match to Ribosomal_L18e Score 461.74" FT CDS complement(17033..18457) FT /db_xref="GOA:Q8TFH0" FT /db_xref="SPTREMBL:Q8TFH0" FT /note="pB17E12.C.cand.1 score = 43.30" FT /gene="SPAPB17E12.14c" FT /product="6-phosphofructo-2-kinase; FT fructose-2,6-bisphosphatase" FT /protein_id="CAD27507.1" FT /translation="MVGLPARGKSYIVNKLVRYYNWLQYNCKAFNVGNFRRKHASHSHD FT DASFFDPSNEEASKLRESFAMDTLDALLQWFEEEDGVVGIFDATNSTSKRRKAIVDHLS FT KVPYVTTLFIESICNDEQLIAANMRMKLVGPDYKDLNPEQSLRDFQERVRMYERKYEPL FT GKSEEDLNLRYIKVINVGKKVVAFNIRGFLAGQAVFFLLNFNLSPRQIWVTRHGESVDN FT VRGRIGGNAELTPLGRQFSEDLALFIDEKRDEFQERLYNDYSKESHLLQHGSHSFNGKQ FT FETSFNCLTPSENTVNDPQVLDPEDEERLEKPYSVWTSMMQRSIQTAAYFDEEQYDIKA FT MRMLNEICSGICDGLTYEEIKSIYPKEYEARKLDKLNYRYPGSGGESYLDVIYRLQSVI FT VEIERMKHHVLVIGHRVITRIIIAYFLGCRREDIAYLNVPLHTVYCIEPQPYGTDFYQY FT NYDPNTRKFSRVPFSL" FT misc_feature complement(17105..17824) FT /note="Match to PGAM Score 195.93" FT misc_feature 18210..18881 FT /note="PCR from cosmid" FT misc_feature complement(18458..19039) FT /note="possible N term of SPAPB17A12.14c" FT misc_feature 18973..19082 FT /note="nominal overlap with SPAC1565 S. pombe chromosome 1" XX SQ Sequence 19082 BP; 6157 A; 3332 C; 3322 G; 6271 T; 0 other; cgtccacata tagattaaat tttgtatgca aactaatatc accacttttc ttttgatcct 60 ttaccaaaaa gtcgagtaaa ctggaagctt ctggacgatg tgaagagatc aattcgtttt 120 tataatcaga aaagttgttt tgaacagctt gaaaatttgc attataccac ctaatggtag 180 tggttgttcc atatggtatg agacatcgct gattttgaaa agtaaagcaa ttccgtaaat 240 tataaagaaa cagaatttta tatctgcatg ttagaatggg catatgtgct gctcaaaaca 300 ccaattcacc aatgaacaat gggatttggg gataaagcac tgatctgtat attgtgtaga 360 gtaagtgcct gattaagtgg ccgcagatgg tgttacttgc gttgacagaa gaatgaatag 420 tacaatttcc tacatatcta tatgttttat gtttattaaa ttagttcaag gataggcaat 480 tctgtctgag tgaatattct cccagtttta gcttcttata cacttcaaaa aaatgcaaaa 540 ctttgaactt ctttgaaaat aagaacaagt aataaatttt atgatagtaa aggaattatc 600 aagaaatagc taaaattagt tttagcatta cacttgatca agatagactc ttcacattga 660 tagttctaca gatacctctt taaccttacc attctattat actagggtaa tcttcgattt 720 acgaaacatt ccttgttaac taactacaaa cgaaaagttg ccggaaaaaa acagcctaca 780 ttccttgagt attttcatga aaattcggta attcttttcc atttggttta tatgagaagt 840 ttgcaattgt acaataataa ttcaaaatgc cctcgaaaag aaaaagaaat cctttacaat 900 atcagacttc aggatcatta gatgaggaaa caaatcaacg cagcgctttt ccacaaatcg 960 acaacaatag tgcttcagaa tctttggaat atgatatacc acttgatggt ttagattatt 1020 tagcaactgt gaggtacgaa catttatata tgaatttttg tgaaaatcga aatttgcaac 1080 atgaatgctt taatctaatc attgtaacaa taattgggct ttttactgac aagttcagag 1140 aagaagctcg caagctagtt ccatttgtag cggcgcgtcg tgagcctgaa acaagagaaa 1200 ccattcctct tcgcaaattg gaaatcgagg ccggcaaaaa aagctttgac ccgtttttac 1260 gatacttact aaacataatt gataaagaag gggaaaggct tgagcaatat atggaatctt 1320 cttcattgga cgcatctatt ttacctaaaa atttacaaca atggcgtgta tatattgagc 1380 ataaagctcc ttgttgggcc atattagcag tggttgattt ggcaactgtt ttggagatcc 1440 tagaaagctt gtccagctgg cttgaaaagg acgcaattga tttacaggtt ggtaacaagg 1500 atctcatgct actttgctgg tgtatttttg ttcattctaa aatttgctaa catttttcta 1560 gagtcaatgg attttttgct tttgttataa acttcctgag cttttgaatg gagaagatat 1620 atcgacccta cgttcagtac tcaagtcttt acgaagtacg catacttctt ttcctgctct 1680 gcagatgtca gcatctgccc ttcaagcagt cttagtttat cgatatggac aaaaagatct 1740 ctttcaaaca tagagtctat aaatcttggt cgaaaaaaat ttaggtacac atgttcatat 1800 agcatacgtt tgtttatagg gaaaaaatta aaattgatag cttgttttaa atatgttttt 1860 aggatattat tccattaaat aactgtttaa aatttcagtt tttatttgca aatttacagt 1920 aagtactcaa actacaaaga ttctaatgga tctagttcag tcctttcctt gcttcaacgc 1980 acttgtctaa ggagctattc agtcaatgga ttcgccttca ttattggaag ttttacaagt 2040 tcaacaggtg gaaaaactta tatcaccttc attaaggttt atactagcag taagtaaaat 2100 aaataaatga tgataaatta atctctttca gtatttcaca catcgatatc caagattttt 2160 attacgggca tataattctt ttgatggtat ttatttattg gtaaaacttt tacttgagaa 2220 atctcagctt aaaaaatgga atgctacatc tgttgaaaga aggtttcaac tcaaacgagt 2280 aatagcggtt cgtgacagta gtataatcgc tgaggaattc ccacaagaat cagagtccgc 2340 tacttcgctc aatgggattg acgtgttaaa aaagttgttt ttaacttatt gcataccata 2400 tttgcttgaa aagtgcgaat cgttaacaac ggttaaagaa aatcatactg ccgtttctat 2460 tctctcatta caggctcgtg acaagcagaa aggggcttta agtgtatttt attcgaaaat 2520 taagatccta cttgtcaggt tgaagaaaat tttgcatttt gtatttcgtt tgataagaaa 2580 atctaatacc tacttacagt ggttgtacta tttactttat gctttgggta aaactcctta 2640 tacaaacctt gctgatcaca tattaagaca acgtgtgatt tataatgtgg aaaatatcca 2700 ttctcgaaaa ctaatttcta ccagagagaa atcttctcta ttaacgtcta ttgccgatca 2760 cagcatggaa ggatttttga tcattataca attgattgat tggtggcaat ctaataatta 2820 tgaatctcat cttaaaaaag gggaagtcgc ttttactgaa ttggcaccgc caaagttacc 2880 ttttgagatt aatgtttcca ctaccgacat ttgtaaaata tgtggagaaa aaataaaaaa 2940 tccagcggtt ttgtcgaccg gtttcgtctt ctgttaccca tgcattcaag tatggttaca 3000 gcgacatcca ttcaaatgtc ctgtaacgaa tttggaatta tcaagaaaag gcgaatcctt 3060 ttggagacta atgatttaaa agctctgctt tttcattttt acttttatta ttttctaagc 3120 agaaggttga gggatacttt actacttcgt ggcagtattc cacaactttt gcacatcttc 3180 aactagctga ttatgtatgg tattttttgg ttgtgagatg gtgaatacct cattaaccat 3240 gtcaattttt ccatttacac gttcatcaat gatcaatcca accaatgctt gttcaataat 3300 agaaatagag acacctagtt tcttagcaag caagctcagc ttcaccgaag tatacggctt 3360 aactaattca atcaacacct ggcttcttat gctatacaaa attttgtcaa catattgacg 3420 aataaaatca tcgtccaaaa tatcgtgttg ataggtttgg agtattcttt caactgcagt 3480 tatatcacgg atttggtatg cttccactag ttttgtcata gcaatgatat gcggattatc 3540 cttataaggt tgagtctctg gagaatcgaa tggattaatt tcagattcgc taagcatgtt 3600 ggccaaaact agatacttca aaacgcgaat tctatccgaa gaaccggcct catcatatga 3660 tttaaaagac tcaaaaaaat ttgtttgagc ttctgaccat tgattttctt gcatatgcat 3720 tttacctccg cactccctaa tgatacccat aattcgggga tgcggtattg cagtttttac 3780 tcgtagtgaa ctttgatata attcttttag ccgtttgtta tcttcaatat cggaatacat 3840 ttggatttct agagaataca actctaaaag atgagttcca cggttttgat ctgcaacaga 3900 attattttcg tccgacaaaa gctcatgcat ttgccgtaat aaatacttaa atttgtgata 3960 gttcttttga gtaaggagga aacgtgccac gtgcattaaa acttttagca tcagtcgttc 4020 attgtttaga ttttgtaacg ctttggtcgt aacgtcgtaa aacttttcca aaaattcggt 4080 gttttcacaa ctagaagcat attctactat attataaatt gatttttcag aataattttt 4140 ggtaatgctt aaccaattgg tataacccaa caatcgttga taactttgca acatcttaaa 4200 acccaataat tagaaacagg ttaaaattta gatccatttt tacttacgtc gtcatatttt 4260 tttaattgaa aattaatttt tgtgatttgt tttagagctt tgaatgccct ataagagtta 4320 gaatcaccat tgctcccaaa ttcataccat tcattttgtt cgccttcaca cttctccact 4380 atactgtaga aagaagttaa cgcggactcg ggattctcct cttttagtgc ttaaaatcga 4440 ttagttgtaa ttcaaatctc ctaacttaca tttggaattg tagtaacagt tttctacatc 4500 gacataaggc tcaatcatgt catcatcatc gtcttcgaat tcaaaatcat aattctcatc 4560 atctctgttt attattaatc aaattgtgca caagcagcga ccttactcta gcataaaatc 4620 attagacatc gtaaggaggt taaagttgaa ggcagaagac aggcatgtat ggaatagtgt 4680 gtaaactttg ttactacgaa acgattaatc ggtgctaagc tagatataag tttctgacga 4740 aaattaattg tagtaattac aataagtaaa tataattcta aagttttgat aaaagctata 4800 acgctaatat tgcgtaaaca attggatgaa acgaaaacac cctggtatag taaagttgat 4860 ttgtttcata aattttgtat atgttataaa caaaacttta tgtacttgaa attatttttt 4920 ataaagtgag aacgcccagt tgttcattaa agtactgctt ggacatattt gaacagagct 4980 ggagtaccta atttcaataa ttctttattt ttgaaacact aaaagtttta gagatcaaaa 5040 tagcaattga aaagtatttt tttttttatt aaaaaaaaaa tttattaaat tttcctttgt 5100 tggaacatat tttagaacat gggagtgcca gttaaaacta aaaataatat tgttttgaaa 5160 aactacatct taaagtaaat gatcatcgaa tgtgctgtca gtactacgac aaacagacct 5220 ccgatataaa ccgacacttt aagtacttaa gttaattatt attcttagca tcgtatagat 5280 actgtcaaaa ttttttgtaa aatataaaag ttcaaagtac taaagcatca ccatcatgca 5340 tcaaataata acgccctaga tatttgttca ctaaatatgt aaacaaaaga tgattgaagt 5400 acagtaacaa tagacgagct atgagagtag tgaggtttgt tttaaatacc ttattgtgct 5460 aatactgaaa cacattgtaa tcttatcgcg cattttatca ataaagtagt gtagtgtgca 5520 caacttatac gctactttgt ttggtagtcg tgactgtctt tctcgaggtt ttgctaattc 5580 atcgtacaca ttaaaatcta tcagtaacct tctgccatcg gccctaatag tttcgagaag 5640 cagtttcaaa aatgactaag ggtactcaat cattcggtat gagacataac aagtctcata 5700 ccatttgccg tcgttgtgga aagcgttctt tccacattca aaagagcacc tgcgcatgct 5760 gtggttatcc cgctgccaag actcgtagtt acaactgggg tgctaaggcc aagagaagaa 5820 gaactactgg cactggccgt atgagctatt tgaagaaggt tcatcgcagc tttaagaacg 5880 gattccgtaa gtaattgcac gatcggtgga gatcctgttg tatttttcgt ttatttatta 5940 acattttatt taggtgctgg caagcctact tccgctgcta ctgcttaggt attgcattaa 6000 tcgatttatt ctcgaaggag gttcatttct ttcaatgagt gaagtgcgta gtaatgttaa 6060 atgtattcat cgtatgctta taatgtaatt taagttcagt aaaaattggc ttttttgtac 6120 cgactttgcc ttgtattgat acaaacgtga taaatctttt tacgtcttaa aaatagtcta 6180 ttacaggata tttgtggtgt ttccagcacc acaaatacta aaaaccgtgg cagcagacat 6240 gaaaggattt tacgtgcaaa aataaatcac ttcactcgtg ttattttggg tgttttaatt 6300 tctcattttt atctcttccc aatacttgaa atataagctg gccaaagaat gctggtagta 6360 cagtttgttt gtgtgatttt ttctagaatt taaacaatta tatttgcatt ccattccgat 6420 atttttcacg aagcattgtc aatcggtatt ttaactggta ataaatttga tactatggtg 6480 gtaaaagata aaagataata ataattgtta tttttagtat aatatattac cgttaagctg 6540 tttattttga taaaacattt tggttgttta agtaatttta ataatgaatc gtgtttaatt 6600 aatttatctc agaacaaata atggtttcca ctgtttcatt cttttaatga ctcaattctg 6660 caaaatattc agcaaatttt atttatttat ttattagaat ttggtttatt agactgcaaa 6720 agcttaagca tattctgatt ccctgatttc ttattacaaa acaatttcga ggttacatcg 6780 acgataccaa tggatcaaaa taaatcgaca caggcaactg gaaatggaaa gaagacagag 6840 gaaataaatg aattgcttga aagttttata aaagaaggtc ctaaattact ttgggggtcg 6900 acgaatttga aatacgaaga ccaaataagt cgttcgtcag aacatgaact tcagcaatat 6960 agggttcgtg aatttctaaa aaagcatgag tttatatttt ataatttttt aaagatgtcc 7020 gtgaaaaaga aattgtacta attactcgat taggaacttt ttactcgatt gaagttttct 7080 tatatcgagc aagggacgaa ggagtacgtc gcagattatt tttacaagtt ttaaatatgt 7140 attaacaatt tgaaaaggag atatttaaga gccatactgg atgacccacc tatgctcgtt 7200 gaagcggaag acaatgaaaa attaggtata atatatattg aattttattt ctgcagactt 7260 ttatttttac taatgagact taaagaaacg acaaattctt ctcttaaggg gaggcttaaa 7320 tccgaaaaaa gagaagttga tttgctcaca gaagagttaa agacaacgtc tagggaatta 7380 tcttctagta tgttaactgg aatttttttt acttattgac atctttaaga ttatgaatca 7440 gtgatggaag agtgcaaaaa cacaaagtct acactctcca agctcgaaag tctggaaagt 7500 gaattgttaa aactacaaca agattcttca acaaaggtaa taaatgtttg gattataaga 7560 tgctaaactt ctagactccc attttaccag aggttgaagc agctattcat gacctcgaaa 7620 gcgaattaaa catcactaat gaatccatag aaactatcga tgggaagata gacaatgatg 7680 aaaaatactt tatacaacta accaaaaacc tttctttact tgaaaaggaa tataaaatag 7740 cttctgagag gtctaatcaa attaaagcag caatccacac tagaacgccc gatgctgacg 7800 caaaaaaaca agtgcaaaat tggtatacct cgatgcttga aatttatgat caacttcttc 7860 aaaaataaat aaaaaaccaa ttttagtaat aatgtatgac actaatctct attcctgcta 7920 ggaacccagc gccttaaggt tacacatcga attaaatatt gtcgaagtac agactctgcc 7980 caatcccatt cattcattga ggcttgattt ttccatattt tattaaagtc ttcaatgcta 8040 ggacattgaa catagcataa tattaggctc tttttcactt gcgcaattac ccgatttaga 8100 caatgaactt catgccattg catgttatat ttttgtttgt ttccaacaca tggaattagc 8160 aaaatagcaa actcggcatg gctgaaaact ggaccctttt tgtacaatac tatttcttgt 8220 taaaaaaatc tgaagcgatg tatataataa acttacaaaa atccaccgaa aatttggttc 8280 cgttttttac aacccaacct tgctgacgaa agtagaaata agcagccaat tcagttaaaa 8340 atttgttgtc cggctcaata atagggtctt catggctttg ctgtaaagaa taatcatgag 8400 taagggcaac tgaattagca actatgttgg caaaaagctt taaaataggt aaaagttcaa 8460 aattagggtt ttcgtagttg attcgaagga ctcccaaaga agctaaaaaa aaggcttccg 8520 gaaatgttag ctgtaggtgc tcaacattag gcactgaagt aatatggtat ggattttcgg 8580 aaactcggga aaagtcttta agagatttcg ttaaatactc aggaagttct gcatcttctt 8640 ctaaagatgc tggaatcggc ttgccatttt ctaatagtaa ttgcctctca cgagcacgat 8700 tttccctata agctctttgt gctttaaatt gttttcgctg aaatctccta cgcgcggtaa 8760 cttcctcagc tacaaggtct tcatcaaatc caagaagtcc cagcgatcgc ttagttcgtg 8820 tatgccaagt tggctcgcta cgagacaaat ttccttttcc aaaaaaacct gatgtccaaa 8880 attttttaat agcttcacta tctgttacaa cacagctgag gtcactttca tgaagctgac 8940 attgccattg tacttgcctg ggtgtctttc taaataggta ccgatatata tatggtatcc 9000 aggttaaagg attagtaaga ataataggag gaagaggata agctaaagaa atagggagcg 9060 catccttata aacttcatga tttttcgaca ttttttgtga cagtaaaagt agtaacacat 9120 taaatactaa atttatatta gcacataaat tagagaaaaa gtatgtttgt ttctcttatt 9180 tgcagactgt tcgagttaca gatggcatac atccaagaat tgggttcaga actagcaatt 9240 actgcaacta ccctaatttg gtggtgataa atatttacaa ttctttagct ttctttgatt 9300 tacacatacc gggatagaaa ttctaaaaaa acagtataca ggaagcatta aatttaaatg 9360 cttttgcata aataaaacaa tttctgtata aaaaaaaaca ctttattgac atactagagg 9420 gcgttattct taaatttttt gttcctaagc ctactcgtgt tttttctgtt tgtacaaata 9480 cttatacctt ttgttctaaa aggaatttaa tattaagaat cggtttcata agaagttata 9540 cacaattcgg atttactatt cttttgtttc agctaaacga cttaaaagag caattgaatc 9600 cttggtttat ggttttcact tatgttttat ctcaactgtt cagtcaattt tcatttctta 9660 aatttttttc ctttttttaa cactccttaa tgaaacagta cttgaacaca gttatttcca 9720 accctagacc agcacaagcg ttgggaatca atcaaccatt tgtagtattt tgctttatta 9780 catctcgtgc tctttcattt gtacctgcga tttactggtg cttcaaatgt ttacatctag 9840 cttttgttgc tgacaagttc aaatggctcc cattaacatc ggccctatgg actctggtaa 9900 taactcgtgg ataatgcata atactaattt ttataggtat ctgcttattt atcttttgtc 9960 ttggcgaatg gttttttact taaatggtga gtaagcatag tagttcattc catgatgttt 10020 attactaaac cgcttaattc atttgcttag ctaactatat ttgtactagg ctgatccatt 10080 actcaattgg acctaccatt ataaggctct tttcactcaa cgtgataaat ttttcattcc 10140 tatcattaag cgttagtttt attacacatg gcgacaacgc ttatttactt ccagcctgga 10200 ttgctatctc ttgtttccag actgcagcct acatagttca agattggatc acctctccca 10260 taattagaac acttcctttt cgttcctcat ccagttcatc ttccaattat cgacacaatc 10320 tcgatttttt agagatcacc gtttttgctg tcgtgccagt gggtattgca agttttttta 10380 cgatggttat gcttatttgg caactttaca aatacccgga ttctttttta gtgtctgcgt 10440 aagtcattgt ttggatgaat tgggactatt tggactaaca cgaaatgttg ccttcagttg 10500 accattgaca gtctctacaa aattatttaa cgttaattat tcttttttta atctgtttgt 10560 aaattttcat tagtcattaa gtttgctaga atactttttg acaattgtgt tgttctgttc 10620 ttttaattct ttgcatatgg gatatactta catgaaatat aatttgattg ttattttttg 10680 ataaaatata gtttatcttc tgaattactt gacaggttca cgaagatcct tatgattttt 10740 cgaatgttcc gtttaagttg tttacatttg tcacatagag taaacataac gtatcctcaa 10800 caaacttcat tttaaaaatg caagaccgct ttttaaagga aaatacggaa ataataaact 10860 tatcttcaag cattcatccc aatagggata gttatttgga ttctcaatcc gaccccttaa 10920 accaaaacct ctataatatt gaaacagaaa acgttaaaga tttaaatatt gaagatgtag 10980 attattatga aaagttgcaa aatttcaaaa ttgttgacga aaacattgat ccaggtttaa 11040 ggacatactc caaaaggtct gttggggtga ataatacttt ccaaaatccc tgtaatagaa 11100 aaattgaggg ctatataaaa gaaattgaaa gactcagtaa cagcaataaa aatcttcaag 11160 cagctgtact tcaaatggta tgattatatt tagtataatg caaggtctga ctgctctcat 11220 taggccgtct cggacaccga tgatccaagg ttaaaagagg aatataagca aacagagaag 11280 gaattactta gagaaatttc cggcaaccat aagtctaaaa ttctaaaatt agaagaagag 11340 ttaaatgatt taaagcactc catgaaagaa atgcaattgt acatgacaaa aatcatagac 11400 aaagcaatga acaacgcttc gctcgaaaat ctgttttctc tagatgagaa taacacaaaa 11460 atccacgaca aataagttca ggaaaaggga aagaatgttc ctcttatcaa caaactatgt 11520 actaaaacct ttaaatgttc aaaagcttag aatgacatga cagctgcttc ccggaacaaa 11580 aataaactgc atatagctca tctttaattt tagttttaaa ttgaattttt tttacacatt 11640 taaagcacat agataaatcc tcagcaaaac ttcgtaaatg tgaactttcc aatactttac 11700 aaaggaaaat tccatctggt ttcagtgctt ttatggcaaa taataaagct gcctgggcaa 11760 gataaagcga atccaactcg tccttaactg ctaaatgctc attagtttgc atagctaaat 11820 aaggtaattt tgaaatccaa aattcgaatc cctgaaccat tggaaatggg ggacctaaat 11880 cactcattat aacatctgct gacaaatctt caattttggc tttctctttt gtatctcttt 11940 cttcttcaaa gactgactgc aagtagggaa tagaagcaga attatgatct tgttgatttc 12000 gaaaaaaaga gtttcgacta cgaatggctg ccttagctat ttcaagctga atttccatac 12060 ttagtatatt accttgaatc atactggagt tttcagggag cctacaagga attatatcac 12120 atgcaataac tctaccaaac aaaccaacat gtcgagcagc tattgtactc catattccag 12180 gtgcacaacc ctaaattgat tagttgcgta taaaaatttg accatttacc taccaaatca 12240 acaacaatct gaccaggttt gaaaagctga tgctctttgt ttatcttaat agttagcaat 12300 aaacaactcc atagaaaaat attaattgaa ccttgaaaag ttcagcagat atacggaata 12360 tgtacgacag tttcttagat gcagtatgct cctaagaata ccttgcaacg gacgtctgtt 12420 gacatttcga cgggaccctt ttaacaattg aacttacttt ctcaatgaat ttttcatttg 12480 ctgtctcagc tgactttctc agagatatta aagtattctt ttttgtcttt ttaggagggt 12540 tggaataaaa acgtaataaa caacttgaaa agagagaatt gttaaaccaa gaagaacttc 12600 tggctatggc cgaataagca gaggaacttc tactccaaat tctcatagac atattatttt 12660 gtggaaagca ttatctaaca tgaatagtca ctgatagtaa atatcaacat ataataattc 12720 atgggcaatg taaaaacttg actaggagat tttgataaat taggaaaaaa aaggtataaa 12780 aaattgttga ccaggtgagt ttgttagtaa agaaatgctt tttgatcgag gagactatgg 12840 ttgcggaaca acgtaaatat atacgaaaat attaaatgtc tggcaagaat tataaactat 12900 tattatggat cgactgcagg tatatttgga gtaaatggca aatataaaca aaatatattt 12960 acaaactata aagtaattag tccctggaag taaaaaatta taatatactc taaagctaat 13020 gataataact tatattatta aacctttaat agaaagaaaa tttatttaac taatcccaag 13080 aaatcaaaag ctttctgttt attctttgaa atctcttaag tttgtttaat gaattgcaac 13140 ttcataggta acaaatataa cgaatctctg cgcatcgacg gtttgcttag cgggggcagc 13200 cattaagcag aaatgaggct gccaaggaca aactattgaa ggcaagatga atttcttcaa 13260 aatcctctcg tttttctccc tctttgtaat tacatgcttt gcaaaattag atttaaattc 13320 aaaaacggat gctgatggag ttattcaaat taccggcaga ttgtttcatc gaatcgtaaa 13380 tggaaaacaa gatttcacca cagtagctct tttctcagcc gattcctcta ccatgaactg 13440 tgatgtttgt cggtaagctc agaaaatatt atattaagtt gatttatttt ctaacgttgt 13500 tagtctcatt gaaccggaat ttaaagcgct tgctaattcg tacaagttaa aatatggtct 13560 tgacagtgga atacgtttta cctacgctga ttttggaaag aataagaatc tttttcagga 13620 cgtatgtgat gcagtcttgt aaattttccc aactttatca atactaattg tactcatagt 13680 tttccattga aagcgtccct aatttttgga tttttaaacc aaaatctatt caagctatcc 13740 acgtagactt aagccatggg taagtccaaa cactcatctt tcctccgaaa ttgtttgttt 13800 gcgaatactt ttttttagta attcgccgta ctatttttag tttttttgaa gaaataaaaa 13860 aactaactta cttagtgtca ctgcttctca tcttgctgct attgtagaaa agcatactgg 13920 gaaaatcgcc gatattgtat ataagcaaga tcaagccaaa cgggttggtg cttttctttc 13980 ctatattatc gttggagctg ctttattctt tacccgtaaa attattgtca aaatctttac 14040 aagtcgcaaa gtttgggccg ccttaaccat tatcaccgtt attactttaa gtagtggtta 14100 catgtttact cgcattcgtt tcagtcctta tagtcaacgt ggtgaacacg gtgaaaacct 14160 ttggcttgct ggttctcaac aatttcaatt tggtgctgaa gttcaagttg tttccctatt 14220 gtgtaagttt gtcgttaaaa ttttaaagtg attctctaac atttttagat accgctttaa 14280 ccatgtcttc catcttcctt gcaatcgttg ctcctaaagt cgaaggagcc aaacgccaaa 14340 ctttgttcgt tataatatgg ttggcattcc tttggattgg ttatagtttc cttgttgata 14400 tttttaagag gaaagttagt atgtatccat ttaagcttct aatttaaaga aatgtatgac 14460 ttaatgaatg ctgcttgagc ctactgctat tcattctttg actatgttgt atccgggaaa 14520 gttcgggttc ttatgcataa aatcattatt aatttacaaa aatttctaat atgatatctg 14580 tagtatattt caatagtagg ggtatgttgg gtagcatcat tttgaaattg acaagacgac 14640 tcttaattta aagatcgtga agcattttac taacagtttc atatgtatac catgtaatac 14700 tcataacagg gataattttc aacatattgc tcgaatagcc acgaaaaaat ccattgattc 14760 cttcggtttt atatatatga aatattgcgc tttttatatt tttataattg tgtccaatac 14820 caggaattct attcacttga aatcgccgtc gaagtacatc agcaggaaat gttagtgttt 14880 ggccaataat cccggtaaac ccacccaaaa agagcttttg aaaagcagtc aagtcagcat 14940 ttgagaaaaa tttttgtttg caaaattcaa atgtaaaaaa acatattgag acatacggaa 15000 cgacgttcaa taaagtggca gggagaccat tataaagggc aggatatcca ccctcatgct 15060 gaactatgta taatagagta gaccacaaag taagaggttt tactttcaaa gaattattag 15120 cgacattatt gattgctaag cttcgtgatg ttagtccagc tgtctcaatg gacaaacgcg 15180 ttcgtgcaat gtccaaagga tatgtcgtag cgcaactggc agcaccagca attgcgccaa 15240 aaagaagcct ttcatgattt tccaaattct gatgtgatct attttttaag gctctttgtt 15300 tgagcatatt gaaagtcgcg aattgtacgg ccccgtaagg aaacgctctc aagcagttcg 15360 taccattgcc ccgaaaaaaa cctatgaggc cttcacggtt ccatattttg acaagtgtcg 15420 aagtgagaga agtatattct ttgttgtttt gaacctgaaa aatgatcttc attcgttcca 15480 gtgggcttac cgctgtccga ctaacggtag cagcaactcc tccggataac atagaaatca 15540 aatcattgct caacagaggt atcctagaag gtgcacaagg gccaaatttg tccttttgca 15600 tgatccttca caccaatatc atgtatcccc caaaaacaat gtgctcaaac actcataact 15660 aaccctaccc taaaaacaaa acaaaacagt cacacgacaa tacacaactt tagaatgaga 15720 attgacacct acaccgagcc aagatggtaa gtaaatgtcg taactggttg ttttccggtt 15780 ttcgtgagtg agaattttaa actaataaat ttattagggt attgacatcg agagacacca 15840 cgtcagaaag tctcagcgca gcaagcctgc ctccgagaat gtgtacttga agcttttggt 15900 aaaattgtac cgattcttgg cccgtcgtac ggattctcgt ttcaacaagg caattttgaa 15960 gcgtcttttt cagtccaaga ccaaccgccc tcctatctct atttctaaga ttgctgctct 16020 tactagccgt aagagcgctt ctctcgaggg taaaactacc gttatcgtcg gaaccgttac 16080 tgatgatgag cgtttgttga ctgtccccaa gctttccgtt gccgcccttc gttttaccaa 16140 gtctgctcgc gctcgcatct tgaaggctgg tggtgaagtt ttgactcttg atcaacttgc 16200 tctccgtgct cccactggaa gcaacaccgt cctcttgcgt ggtaagaaac atgctcgtga 16260 agcttaccgt cacttcggtt tcggccccca taagcacaag gctccttatg tccgttctga 16320 aggtcgtaag tttgagagag ctcgtggtcg tagaaagtct cgtgccttca aggtataagc 16380 atgttagtat acaatataca tgcccaaaag tttttcaagt taatatgggt gcattcttta 16440 tatttgaggt ttgtattgta agtatgttgt tctagtagtt ttcggcttac aaattgcttg 16500 tgtaatattc tttttttgtc gctttagtac aatagttcta gacagtttag taagatgtgg 16560 aatgtttgta tttaaaaatt tctaccgtac agcatcgtat atgaaggaac aattagcgct 16620 ttaggagatg gctgccaatc tatcttaaga gtctccccgc agtagtatct atttggcact 16680 ttttcactgg gaatgcaaac aactattgga ccttgtttat aatactttat tatccacaaa 16740 acgacagata aataaaaaaa ccagatataa attagtagta aacccaaaaa aagagactag 16800 aagcgaactc ctgccagaat ctagaagaga taaatcataa aaacattata ttccaactca 16860 ttaaatatat aaaccttctc aaaaacttta tttttcttaa aaaaattctg acaaaagagt 16920 ataaaaaatg ccgcgtcctc gagttcaaac tacggaaggg cagtgatcaa cagattacat 16980 gtttgaagtc ctaagacatt ttgtctagta tcatgacaat taaaatatat attcaaagtg 17040 agaaagggac tcttgaaaac tttctcgtat taggatcgta attatattgg taaaaatcag 17100 taccatatgg ttgcggctcg atgcagtaaa cagtgtgaag tggtacattc aaataagcga 17160 tatcttctcg acgacaaccc aagaaatatg caataattat acgagtaatc acgcgatgac 17220 caattaccaa aacatgatgt ttcatccgct caatttcaac aattacactc tgtaatctat 17280 agataacatc aagatagctt tcaccaccag atccgggata ccgataattt aatttgtcta 17340 gttttcgagc ttcatattcc tttggataaa ttgacttgat ttcctcgtac gtcaatccat 17400 cacatatacc agaacagatc tcatttaaca tacgcatggc ttttatatca tattgttctt 17460 cgtcaaaata tgcagcggtc tgtatactac gctgcatcat agacgtccaa acactataag 17520 gtttttctaa tcgctcttca tcctctggat ctaaaacttg gggatcatta acagtatttt 17580 cggagggtgt taggcaattg aagctggttt caaattgttt accattaaaa gaatgggagc 17640 cgtgctgtaa caagtgtgat tccttagaat aatcgttgta taaacgctct tgaaattcat 17700 ctcgcttttc gtcaataaac aaagctaagt cttcgctaaa ttgtctgccc agaggtgtca 17760 actcagcgtt accaccaatt cggcctctaa cattgtcaac ggactcgcca tgacgcgtca 17820 cccaaatttg tcgtggagaa aggttgaagt ttagcaaaaa gaacacggcc tgtcctgcaa 17880 ggaatccacg gatgttaaat gcgacaactt tcttcccgac atttattacc tttatatacc 17940 ttaggttcag gtcttcttca gactttccaa gcggttcgta tttcctttca tacatacgaa 18000 cacgttcctg aaaatctcgc aaagactgct cagggttgag atccttgtaa tcagggccaa 18060 ctagcttcat tctcatgttg gcggcaataa gttgttcatc attacatatg gactcaataa 18120 acaaagtagt cacataagga actttactaa gatggtcaac aatggccttt cttcgtttgg 18180 aggtagagtt tgtggcatca aagatgccga caactccatc ctcttcttcg aaccactgaa 18240 gcaaagcatc caacgtatcc atggcaaacg attctctaag cttggaagcc tcttcgttag 18300 aaggatcgaa gaaagaggca tcatcgtgac tatggctagc atgttttcgg cgaaaattac 18360 caacgttaaa cgccttgcaa ttatattgca gccaattata atatctaaca agcttattta 18420 caatgtaaga tttccctcta gctggtaagc ccaccataat gattgcaagc ttttcctctg 18480 ggggattggt cgcctcggaa ccgttattgg aagaaacgat ggatgtttga cccggaatac 18540 tcatggaaga gccctttttc cgtaaatgat gatgaaaagg aatgggcgaa ggcggtgcag 18600 tatcgcttgc aggatgaaaa ctcggaacgc gatgctgttg tgacataggt ctgtgcgttt 18660 gacgtatgga agtcaactgt tttggaagag caaaataacc gccagaagag actcgcttta 18720 catctggtcg actccctagg ttcagagtgg gagacaatgc aggggaagga attggatgga 18780 cgggagaatt ttgaagcgat gagtctgaaa aattggcaga gttcgatgtt aacgtcgata 18840 ctggtgaaga aaatggtcga tcttcagaag taaccgaatc ggtgttggtg aaagaatgat 18900 cgtttgccga aagcttggga gaaccaaatt tatcaagctg gtcaacatca tcttttacag 18960 gaatagccgt gcgatcagga ttgtaataat gagtacggga ctgcaactcc gagtcatcct 19020 tgttattatt attcgacatg gcaaatatgc aacaagagat aagtttcgag cagaaggtag 19080 tt 19082 //